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$152+ Cheap flights from O'Hare Intl (ORD) to Panama

This is the cheapest one-way flight price found by a Cheapflights user in the last 72 hours by searching for a flight departing on 12/7. Fares are subject to change and may not be available on all flights or dates of travel.
ORD — PTY
Nov 28 — Dec 51
Fri 11/28
Fri 12/5
1 adult, Economy
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Cheap flight deals from O'Hare Intl to Panama

Keep the following information in mind while searching for O'Hare Intl to Panama flight deals. Data was last updated October 29, 2025.

Most accurate provider

eDreams
3 stars

Most trusted provider

eDreams
3 stars

Round-trip from

$451
(Copa Airlines)

One-way from

$152
(Kiwi.com)

Popular in

October

Cheapest in

November

Average price

$700

Good round-trip deal

$437 or less

Good one-way deal

$162 or less
Provider with most accurate pricing for Chicago (CHI)-Panama City Tocumen Intl flight deals.
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Provider most trusted by Cheapflights users for Chicago (CHI)-Panama City Tocumen Intl flights.
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From Chicago O'Hare Intl to Panama
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One-way flight from Chicago O'Hare Intl to Panama
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High demand for flights, 1% potential price rise
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Cheapest flight prices on average. 1% potential price decrease ($12 potential savings vs. average RT price).
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Average for round-trip flights in October 2025
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Price to beat on a round-trip flight from Chicago O'Hare Intl to Panama.
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Price to beat on a one-way flight from Chicago O'Hare Intl to Panama.
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Find flight deals from O'Hare Intl to Panama

Cheapest flights from O'Hare Intl to Panama
Explore the most affordable flight options available from O'Hare Intl to Panama. Find the lowest fares from popular airlines and budget airlines, with prices last updated on October 29, 2025.

This Copa Airlines deal was found by Cheapflights users on 10/29. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Copa Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 11/72:07 pmORD - PTY
Nonstop5h 28mCopa Airlines
Thu 11/137:50 amPTY - ORD
Nonstop5h 56mCopa Airlines
Deal found 10/29$451
This Avianca deal was found by Cheapflights users on 10/29. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Avianca is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 11/2910:20 pmORD - PTY
1 stop14h 40mAvianca
Wed 12/37:50 pmPTY - ORD
1 stop20h 00mAvianca
Deal found 10/29$455
This American Airlines deal was found by Cheapflights users on 10/28. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 11/67:07 pmORD - PTY
1 stop17h 42mAmerican Airlines
Tue 11/112:49 pmPTY - ORD
1 stop9h 10mAmerican Airlines
Deal found 10/28$466
This American Airlines deal was found by Cheapflights users on 10/29. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 11/3012:52 amORD - PTY
2 stops11h 51mAmerican Airlines
Sat 12/64:43 pmPTY - ORD
2 stops15h 57mAmerican Airlines
Deal found 10/29$470
This American Airlines deal was found by Cheapflights users on 10/28. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 12/97:07 pmORD - PTY
1 stop17h 40mAmerican Airlines
Sun 12/212:53 pmPTY - ORD
1 stop9h 06mAmerican Airlines
Deal found 10/28$471
This Cheapflightsfares deal was found by Cheapflights users on 10/29. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Cheapflightsfares is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 12/110:20 pmORD - PTY
1 stop17h 35mAvianca
Fri 12/52:55 amPTY - ORD
1 stop18h 25mAvianca
Deal found 10/29$474
This Kiwi.com deal was found by Cheapflights users on 10/27. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 12/47:41 pmORD - PTY
1 stop11h 25mMultiple Airlines
Mon 12/810:25 amPTY - ORD
1 stop9h 11mMultiple Airlines
Deal found 10/27$476
This Mytrip deal was found by Cheapflights users on 10/28. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Mytrip is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 11/2710:20 pmORD - PTY
1 stop9h 30mMultiple Airlines
Thu 12/411:25 amPTY - ORD
2 stops13h 44mMultiple Airlines
Deal found 10/28$477
This Mytrip deal was found by Cheapflights users on 10/28. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Mytrip is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 11/1410:20 pmORD - PTY
1 stop17h 35mMultiple Airlines
Sun 11/2311:25 amPTY - ORD
2 stops12h 48mMultiple Airlines
Deal found 10/28$480
This Copa Airlines deal was found by Cheapflights users on 10/28. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Copa Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 11/76:56 amORD - DAV
1 stop11h 44mCopa Airlines
Fri 11/149:53 amDAV - ORD
1 stop15h 12mCopa Airlines
Deal found 10/28$481
This Cheapflightsfares deal was found by Cheapflights users on 10/29. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Cheapflightsfares is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 10/2911:20 pmORD - PTY
1 stop9h 30mAvianca
Mon 12/89:45 amPTY - ORD
1 stop11h 35mAvianca
Deal found 10/29$482
This Cheapflightsfares deal was found by Cheapflights users on 10/29. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Cheapflightsfares is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 11/710:20 pmORD - PTY
1 stop9h 30mAvianca
Wed 11/122:55 amPTY - ORD
1 stop18h 25mAvianca
Deal found 10/29$487

Cheapflights Fare Finder

 
Customize your flight search to find flights from O'Hare Intl to Panama that fit within your specific budget. Explore options based on user searches and filter the results based on your desired price range. Find flights that match your budget for a cost-effective journey. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated October 29, 2025.
Use the filters below to find and compare flights from Chicago O'Hare Intl Airport to Panama that are best for you.

Fly from

O'Hare Intl

Fly to

Panama

Route

Depart

Return

Price

ChicagoPanama City

ORD - PTY

ORDPTY

Chicago O'Hare Intl

Thu 11/27

6:56 am-1:22 pm

Nonstop5h 26m

Panama City Tocumen Intl

Thu 12/4

7:56 am-12:52 pm

Nonstop5h 56m

$451

ChicagoPanama City

ORD - PTY

ORDPTY

Chicago O'Hare Intl

Fri 12/12

2:07 pm-8:35 pm

Nonstop5h 28m

Panama City Tocumen Intl

Thu 12/18

7:56 am-12:52 pm

Nonstop5h 56m

$451

ChicagoPanama City

ORD - PTY

ORDPTY

Chicago O'Hare Intl

Fri 11/28

2:07 pm-8:35 pm

Nonstop5h 28m

Panama City Tocumen Intl

Tue 12/2

7:20 pm-12:05 am

Nonstop5h 45m

$451

ChicagoPanama City

ORD - PTY

ORDPTY

Chicago O'Hare Intl

Thu 2/5

2:22 pm-8:35 pm

Nonstop5h 13m

Panama City Tocumen Intl

Tue 2/10

7:20 pm-12:04 am

Nonstop5h 44m

$507

ChicagoPanama City

ORD - PTY

ORDPTY

Chicago O'Hare Intl

Thu 1/8

7:35 am-2:00 pm

Nonstop5h 25m

Panama City Tocumen Intl

Mon 1/12

7:40 pm-12:24 am

Nonstop5h 44m

$520

ChicagoPanama City

ORD - PTY

ORDPTY

Chicago O'Hare Intl

Thu 12/11

2:07 pm-8:35 pm

Nonstop5h 28m

Panama City Tocumen Intl

Fri 1/9

7:40 pm-12:24 am

Nonstop5h 44m

$539

ChicagoPanama City

ORD - PTY

ORDPTY

Chicago O'Hare Intl

Thu 2/19

7:34 am-2:00 pm

Nonstop5h 26m

Panama City Tocumen Intl

Mon 2/23

7:55 am-12:31 pm

Nonstop5h 36m

$563

ChicagoPanama City

ORD - PTY

ORDPTY

Chicago O'Hare Intl

Wed 2/25

2:22 pm-8:35 pm

Nonstop5h 13m

Panama City Tocumen Intl

Sun 3/1

7:20 pm-12:04 am

Nonstop5h 44m

$563

ChicagoPanama City

ORD - PTY

ORDPTY

Chicago O'Hare Intl

Thu 2/12

7:34 am-2:00 pm

Nonstop5h 26m

Panama City Tocumen Intl

Mon 2/16

7:20 pm-12:04 am

Nonstop5h 44m

$563

ChicagoPanama City

ORD - PTY

ORDPTY

Chicago O'Hare Intl

Thu 4/2

3:13 pm-8:35 pm

Nonstop5h 22m

Panama City Tocumen Intl

Mon 4/6

7:40 pm-1:24 am

Nonstop5h 44m

$563

Flights are sorted by cheapest round-trip flights first.

Deals found on 10/28

Showing 1-10 of 34 results
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Best time to book a flight from O'Hare Intl to Panama

Have a flexible travel schedule? Discover the best time to fly to Panama from O'Hare Intl with our price prediction graph.
Estimated round-trip price
Rates are based on past data. Find the cheapest month and day to book your flight based on your travel requirements, then search for cheap deals.

Cheapflights Insights

Everything you need to know about your flight from Chicago O'Hare Intl Airport to Panama

What is the cheapest month to book a flight from Chicago O'Hare Intl Airport to Panama?

Currently, November is the cheapest month in which you can book a flight from Chicago O'Hare Intl Airport to Panama (average of $392). Flying from Chicago O'Hare Intl Airport to Panama in April is currently the most expensive (average of $464). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.

What is the cheapest time of day to fly from ORD to PA?

Find hourly flight availability from O'Hare Intl to Panama. Discover flight options and departure times throughout the day, allowing you to choose a departure time that suits your schedule. Data last updated October 29, 2025.

A simple way to save on the total cost of your ticket is to fly from Chicago O'Hare Intl Airport to Panama in the afternoon. If you’re flexible enough to do this you can expect to save up to 40% on your trip compared to booking a flight in the evening.

What is the cheapest day to fly from Chicago O'Hare Intl Airport to Panama?

Use this chart to determine the cheapest time to fly round-trip from O'Hare Intl to Panama. Price data was last updated on December 16, 2024.

Travelers seeking maximum savings on their Chicago O'Hare Intl Airport to Panama flight should consider departing on Monday evenings when fares are most often at their lowest. Saturday mornings flights should be avoided if possible as fares are typically the most expensive at this time.

Reviews of airlines servicing Panama

Get insights into the airlines that provide service to Panama. Read reviews, discover amenities, and learn about the overall travel experience offered by airlines. Use this information to make informed decisions when choosing an airline for your flight to Panama. Reviews last updated October 29, 2025.
Peruse reviews from past customers who have flown with Delta, Copa Airlines, and United Airlines from Chicago O'Hare Intl Airport to Panama to help guide your decision. You can also see how each airline stacks up in terms of entertainment options, comfort, food, crew/service, and boarding process.
Delta
7.9
Good
7,994 reviews

Food

7.3

Boarding

8.2

Comfort

7.9

Entertainment

7.9

Overall

7.9

Crew

8.5

Reviews

1 / 20
8.0
Excellent

Matthew,Oct 2025

GSP - ATL

This is always a full flight since it is the connecting route to primary destinations through Atlanta. That said, the crew handles the full load well. Not much more to say, it is a short flight with no in-flight services due to the length.
Delta
7.9
Good
7,994 reviews
Delta
7.9
Good
7,994 reviews

Food

7.3

Boarding

8.2

Comfort

7.9

Entertainment

7.9

Overall

7.9

Crew

8.5

Reviews

1 / 20
8.0
Excellent

Matthew,Oct 2025

GSP - ATL

This is always a full flight since it is the connecting route to primary destinations through Atlanta. That said, the crew handles the full load well. Not much more to say, it is a short flight with no in-flight services due to the length.
Copa Airlines
7.6
Good
1,562 reviews
Delta
7.9
Good
7,994 reviews

Food

7.3

Boarding

8.2

Comfort

7.9

Entertainment

7.9

Overall

7.9

Crew

8.5

Reviews

1 / 20
8.0
Excellent

Matthew,Oct 2025

GSP - ATL

This is always a full flight since it is the connecting route to primary destinations through Atlanta. That said, the crew handles the full load well. Not much more to say, it is a short flight with no in-flight services due to the length.
United Airlines
7.4
Good
9,001 reviews
Delta
7.9
Good
7,994 reviews

Food

7.3

Boarding

8.2

Comfort

7.9

Entertainment

7.9

Overall

7.9

Crew

8.5

Reviews

1 / 20
8.0
Excellent

Matthew,Oct 2025

GSP - ATL

This is always a full flight since it is the connecting route to primary destinations through Atlanta. That said, the crew handles the full load well. Not much more to say, it is a short flight with no in-flight services due to the length.
American Airlines
7.2
Good
11,032 reviews
Delta
7.9
Good
7,994 reviews

Food

7.3

Boarding

8.2

Comfort

7.9

Entertainment

7.9

Overall

7.9

Crew

8.5

Reviews

1 / 20
8.0
Excellent

Matthew,Oct 2025

GSP - ATL

This is always a full flight since it is the connecting route to primary destinations through Atlanta. That said, the crew handles the full load well. Not much more to say, it is a short flight with no in-flight services due to the length.
Avianca
6.6
Okay
2,468 reviews
Delta
7.9
Good
7,994 reviews

Food

7.3

Boarding

8.2

Comfort

7.9

Entertainment

7.9

Overall

7.9

Crew

8.5

Reviews

1 / 20
8.0
Excellent

Matthew,Oct 2025

GSP - ATL

This is always a full flight since it is the connecting route to primary destinations through Atlanta. That said, the crew handles the full load well. Not much more to say, it is a short flight with no in-flight services due to the length.

Related info for your journey

Find useful and relevant information for your journey from O'Hare Intl to Panama. Access travel guides, tips, and recommendations to enhance your travel experience. Get information about local attractions, weather, transportation options, and more.

  • How long is the flight from Chicago O'Hare Intl Airport to Panama?

    Departing from Chicago O'Hare Intl Airport to Panama will take you 5h 26m. The distance from Chicago O'Hare Intl Airport to Panama is about 2330 mi. This flight may include one or multiple stops.

  • What are the most popular routes from Chicago O'Hare Intl Airport to Panama?

    When deciding which route to take from Chicago O'Hare Intl Airport to Panama consider Chicago O'Hare Intl - Panama City Tocumen Intl, Chicago O'Hare Intl - David Enrique Malek or Chicago O'Hare Intl - Panama City Marcos A. Gelabert Intl as they are the most popular.

  • What are the most reliable airlines from Chicago O'Hare Intl Airport to Panama?

    The top 3 most reliable airlines when flying from Chicago O'Hare Intl Airport to Panama are United Airlines (90%), EVA Air (89%) and Copa Airlines (60%).

  • What are the cheapest flights from Chicago O'Hare Intl Airport to Panama?

    On average you can expect to pay $757 for a flight from Chicago O'Hare Intl Airport to Panama. The cheapest flight overall is $133 while the most popular route, (Chicago O'Hare Intl - Panama City Tocumen Intl) is currently priced at $451.

  • Can I find deals for flights from O'Hare Intl to Panama that include hotel bookings?

    Yes. In addition to deals on O'Hare Intl to Panama flights, Cheapflights offers vacation packages that include both flights and hotel.

  • How can I find direct flights from O'Hare Intl to Panama?

    After entering your origin and destination, apply the non-stop filter on the search result page to find direct flights from O'Hare Intl to Panama.

  • Can I find deals for business class flights from O'Hare Intl to Panama?

    Yes. Cheapflights offers flight deals from O'Hare Intl to Panama by cabin class. In addition to browsing deals, you can also filter by cabin class on the search results page after making a search.

  • What is the cheapest month to book a flight from Chicago O'Hare Intl Airport to Panama?

    Currently, November is the cheapest month in which you can book a flight from Chicago O'Hare Intl Airport to Panama (average of $392). Flying from Chicago O'Hare Intl Airport to Panama in April is currently the most expensive (average of $464). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.

See more FAQs

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Top 5 airlines flying from O'Hare Intl to Panama

Discover the top 5 airlines that operate flights from O'Hare Intl to Panama. Compare their services, reliability, and customer satisfaction ratings to choose the airline that best suits your travel preferences and needs. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated October 29, 2025.
AirlineCheapestAverageFlexibilityOn-time
AviancaCheapest$334Average$457FlexibilityNo cancel feeOn-time71%
Copa AirlinesCheapest$464Average$672FlexibilityNo cancel feeOn-time70%
United AirlinesCheapest$479Average$653FlexibilityNo cancel feeOn-time69%
DeltaCheapest$479Average$658FlexibilityNo cancel feeOn-timeN/A
American AirlinesCheapest$589Average$737FlexibilityNo cancel feeOn-time71%

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