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$158+ Cheap flights from Charleston (CHS) to Panama

This is the cheapest one-way flight price found by a Cheapflights user in the last 72 hours by searching for a flight departing on 8/28. Fares are subject to change and may not be available on all flights or dates of travel.
CHS — PTY
Aug 7 — Aug 141
Thu 8/7
Thu 8/14
1 adult, Economy
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Cheap flight deals from Charleston to Panama

Keep the following information in mind while searching for Charleston to Panama flight deals. Data was last updated August 2, 2025.

Round-trip from

$374
(American Airlines)

One-way from

$158
(American Airlines)

Popular in

March

Cheapest in

November

Average price

$456
From Charleston to Panama
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One-way flight from Charleston to Panama
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Highest demand for flights based on searches. 19% potential increase in price ($120 potential increase over avg. RT price).
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Cheapest flight prices on average. 3% potential price decrease ($17 potential savings vs. average RT price).
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Average for round-trip flights in August 2025
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Find flight deals from Charleston to Panama

Cheapest flights from Charleston to Panama
Explore the most affordable flight options available from Charleston to Panama. Find the lowest fares from popular airlines and budget airlines, with prices last updated on August 2, 2025.

This American Airlines deal was found by Cheapflights users on 8/1. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 12/16:32 pmCHS - PTY
2 stops19h 04mAmerican Airlines
Thu 12/42:45 pmPTY - CHS
1 stop9h 32mAmerican Airlines
Deal found 8/1$374
This United Airlines deal was found by Cheapflights users on 7/30. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 9/45:16 pmCHS - PTY
1 stop21h 58mUnited Airlines
Mon 9/83:30 pmPTY - CHS
1 stop24h 05mUnited Airlines
Deal found 7/30$406
This Mytrip deal was found by Cheapflights users on 8/1. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Mytrip is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 12/75:40 pmCHS - PTY
2 stops18h 55mMultiple Airlines
Mon 12/83:40 pmPTY - CHS
3 stops19h 05mMultiple Airlines
Deal found 8/1$672
This Delta deal was found by Cheapflights users on 8/1. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 11/195:30 amCHS - PTY
1 stop8h 22mDelta
Sat 11/298:05 amPTY - CHS
1 stop7h 34mDelta
Deal found 8/1$681

Cheapflights Fare Finder

 
Customize your flight search to find flights from Charleston to Panama that fit within your specific budget. Explore options based on user searches and filter the results based on your desired price range. Find flights that match your budget for a cost-effective journey. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated August 2, 2025.
Use the filters below to find and compare flights from Charleston to Panama that are best for you.

Fly from

Charleston

Fly to

Panama

Route

Depart

Return

Price

CharlestonPanama City

CHS - PTY

CHSPTY

Charleston

Mon 12/1

6:32 pm-1:36 pm

2 stops19h 04m

Panama City Tocumen Intl

Thu 12/4

2:45 pm-12:17 am

1 stop9h 32m

$374

CharlestonPanama City

CHS - PTY

CHSPTY

Charleston

Thu 9/4

5:16 pm-2:14 pm

1 stop21h 58m

Panama City Tocumen Intl

Mon 9/8

3:30 pm-4:35 pm

1 stop24h 05m

$406

CharlestonPanama City

CHS - PTY

CHSPTY

Charleston

Fri 1/16

6:30 am-8:04 pm

1 stop13h 34m

Panama City Tocumen Intl

Sun 2/1

3:27 pm-11:39 pm

1 stop8h 12m

$409

CharlestonPanama City

CHS - PTY

CHSPTY

Charleston

Sun 12/7

5:40 pm-12:35 pm

2 stops18h 55m

Panama City Tocumen Intl

Mon 12/8

3:40 pm-10:45 am

3 stops19h 05m

$672

CharlestonPanama City

CHS - PTY

CHSPTY

Charleston

Thu 8/28

6:06 pm-2:30 pm

2 stops21h 24m

$158

CharlestonPanama City

CHS - PTY

CHSPTY

Charleston

Thu 8/28

8:17 pm-5:16 pm

3 stops21h 59m

$315

Flights are sorted by cheapest round-trip flights first.

Deals found on 7/31

Best time to book a flight from Charleston to Panama

Have a flexible travel schedule? Discover the best time to fly to Panama from Charleston with our price prediction graph.
Estimated round-trip price
Rates are based on past data. Find the cheapest month and day to book your flight based on your travel requirements, then search for cheap deals.

Cheapflights Insights

Everything you need to know about your flight from Charleston to Panama

What is the cheapest month to book a flight from Charleston to Panama?

Currently, October is the cheapest month in which you can book a flight from Charleston to Panama (average of $478). Flying from Charleston to Panama in December is currently the most expensive (average of $634). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.

What is the cheapest time of day to fly from CHS to PA?

Find hourly flight availability from Charleston to Panama. Discover flight options and departure times throughout the day, allowing you to choose a departure time that suits your schedule. Data last updated August 2, 2025.

Regardless of the time of day you decide to fly, the ticket price will remain around the same. Book flights from Charleston to Panama as you normally would.

Reviews of airlines servicing Panama

Get insights into the airlines that provide service to Panama. Read reviews, discover amenities, and learn about the overall travel experience offered by airlines. Use this information to make informed decisions when choosing an airline for your flight to Panama. Reviews last updated August 2, 2025.
Get a feel of what it's like to fly with Delta, United Airlines, and American Airlines from Charleston to Panama by reading reviews from past customers. Users have also rated airlines in terms of entertainment options, comfort, food, crew/service, and boarding process.
Delta
8.0
Very good
7,983 reviews

Entertainment

7.9

Boarding

8.2

Comfort

7.9

Food

7.3

Overall

8.0

Crew

8.5

Reviews

1 / 20
10.0
Excellent

Kim,May 2025

PIH - SLC

This trip was fine even with delay I had plenty of time to get connection flight!
Delta
8.0
Very good
7,983 reviews
Delta
8.0
Very good
7,983 reviews

Entertainment

7.9

Boarding

8.2

Comfort

7.9

Food

7.3

Overall

8.0

Crew

8.5

Reviews

1 / 20
10.0
Excellent

Kim,May 2025

PIH - SLC

This trip was fine even with delay I had plenty of time to get connection flight!
United Airlines
7.4
Good
8,904 reviews
Delta
8.0
Very good
7,983 reviews

Entertainment

7.9

Boarding

8.2

Comfort

7.9

Food

7.3

Overall

8.0

Crew

8.5

Reviews

1 / 20
10.0
Excellent

Kim,May 2025

PIH - SLC

This trip was fine even with delay I had plenty of time to get connection flight!
American Airlines
7.2
Good
10,000 reviews
Delta
8.0
Very good
7,983 reviews

Entertainment

7.9

Boarding

8.2

Comfort

7.9

Food

7.3

Overall

8.0

Crew

8.5

Reviews

1 / 20
10.0
Excellent

Kim,May 2025

PIH - SLC

This trip was fine even with delay I had plenty of time to get connection flight!

Related info for your journey

Find useful and relevant information for your journey from Charleston to Panama. Access travel guides, tips, and recommendations to enhance your travel experience. Get information about local attractions, weather, transportation options, and more.

  • What airport do you fly from for flights from Charleston to Panama?

    For a flight from Charleston to Panama, you will be flying from Charleston. Charleston (CHS) is just 10.2 mi from the center of the city.

  • Can I find deals for flights from Charleston to Panama that include hotel bookings?

    Yes. In addition to deals on Charleston to Panama flights, Cheapflights offers vacation packages that include both flights and hotel.

  • How can I find direct flights from Charleston to Panama?

    After entering your origin and destination, apply the non-stop filter on the search result page to find direct flights from Charleston to Panama.

  • Can I find deals for business class flights from Charleston to Panama?

    Yes. Cheapflights offers flight deals from Charleston to Panama by cabin class. In addition to browsing deals, you can also filter by cabin class on the search results page after making a search.

  • What is the cheapest month to book a flight from Charleston to Panama?

    Currently, October is the cheapest month in which you can book a flight from Charleston to Panama (average of $478). Flying from Charleston to Panama in December is currently the most expensive (average of $634). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.

See more FAQs

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Alternative routes for Charleston to Panama

See prices for flight routes from nearby airports that may be better suited for you.
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Columbia to Guatemala City flights
Columbia to San José flights
Charleston to San Salvador flights
Charleston to Guatemala City flights
Augusta to Guatemala City flights
Columbia to San Pedro Sula flights
Savannah to Guatemala City flights
Augusta to San José flights
Columbia to Philip S.W.Goldson flights
Greenville to Liberia flights
Savannah to Panama City flights
Savannah to Coxen Hole flights
Greenville to San Salvador flights
Myrtle Beach to Panama City flights
Augusta to Panama City flights
Hilton Head Island to San José flights
Savannah to San Pedro Sula flights
Augusta to Philip S.W.Goldson flights
Columbia to Liberia flights
Columbia to San Salvador flights
Charleston to Managua flights
Savannah to San Salvador flights
Savannah to Philip S.W.Goldson flights
Myrtle Beach to Guatemala City flights
Hilton Head Island to Liberia flights
Greenville to San Pedro Sula flights
Augusta to San Pedro Sula flights

Top 3 airlines flying from Charleston to Panama

Discover the top 3 airlines that operate flights from Charleston to Panama. Compare their services, reliability, and customer satisfaction ratings to choose the airline that best suits your travel preferences and needs. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated August 2, 2025.
AirlineCheapestAverageFlexibilityOn-time
DeltaCheapest$331Average$471FlexibilityNo cancel feeOn-timeN/A
American AirlinesCheapest$362Average$544FlexibilityNo cancel feeOn-time71%
United AirlinesCheapest$391Average$476FlexibilityNo cancel feeOn-time69%

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