Panama

$152+ Cheap flights from Charleston (CHS) to Panama

This is the cheapest one-way flight price found by a Cheapflights user in the last 72 hours by searching for a flight departing on 2/24. Fares are subject to change and may not be available on all flights or dates of travel.
CHS — PTY
ene. 22 — ene. 291
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Cheap flight deals from Charleston to Panama

Cheapest flights from Charleston to Panama
Explore the most affordable flight options available from Charleston to Panama. Find the lowest fares from popular airlines and budget airlines, with prices last updated on diciembre 23, 2025.

This United Airlines deal was found by Cheapflights users on 12/22. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
dom. 12/286:30 amCHS - PTY
1 stop13h 08mUnited Airlines
mié. 12/3111:55 pmPTY - CHS
1 stop9h 15mUnited Airlines
Deal found 12/22$454
This American Airlines deal was found by Cheapflights users on 12/22. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
sáb. 12/274:13 pmCHS - PTY
2 stops21h 40mAmerican Airlines
vie. 1/22:53 pmPTY - CHS
1 stop17h 54mAmerican Airlines
Deal found 12/22$670
This American Airlines deal was found by Cheapflights users on 12/22. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
lun. 12/228:08 pmCHS - PTY
2 stops19h 46mAmerican Airlines
mar. 1/64:31 pmPTY - CHS
1 stop16h 16mAmerican Airlines
Deal found 12/22$780
This United Airlines deal was found by Cheapflights users on 12/21. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
dom. 12/215:00 pmCHS - PTY
1 stop26h 38mUnited Airlines
dom. 1/44:41 pmPTY - CHS
1 stop23h 29mUnited Airlines
Deal found 12/21$1,104
This United Airlines deal was found by Cheapflights users on 12/21. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
sáb. 12/276:30 amCHS - PTY
1 stop13h 08mUnited Airlines
dom. 1/44:41 pmPTY - CHS
1 stop29h 16mUnited Airlines
Deal found 12/21$1,207
This Gurufare deal was found by Cheapflights users on 12/21. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Gurufare is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
sáb. 12/277:10 pmCHS - PTY
2 stops20h 44mGOL
dom. 1/44:55 pmPTY - CHS
1 stop7h 50mGOL
Deal found 12/21$1,209

Find flight deals from Charleston to Panama

Keep the following information in mind while searching for Charleston to Panama flight deals. Data was last updated diciembre 23, 2025.

Most accurate provider

eDreams
3 stars

Most trusted provider

eDreams
3 stars

Round-trip from

$390
(United Airlines)

One-way from

$152
(Delta)

Popular in

April

Cheapest in

September

Average price

$680
Provider with most accurate pricing for Charleston-Panama City Tocumen Intl flight deals.
Provider most trusted by Cheapflights users for Charleston-Panama City Tocumen Intl flights.
From Charleston to Panama
One-way flight from Charleston to Panama
Highest demand for flights based on searches. 11% potential increase in price ($72 potential increase over avg. RT price).
Cheapest flight prices on average. 5% potential price decrease ($30 potential savings vs. average RT price).
Average for round-trip flights in December 2025

Cheapflights Fare Finder

 
Customize your flight search to find flights from Charleston to Panama that fit within your specific budget. Explore options based on user searches and filter the results based on your desired price range. Find flights that match your budget for a cost-effective journey. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated diciembre 23, 2025.
Use the filters below to find and compare flights from Charleston to Panama that are best for you.

Fly from

Charleston

Fly to

Panama

Route

Depart

Return

Price

CharlestonPanama City

CHS - PTY

CHSPTY

Charleston

mar. 4/14

7:40 pm-4:04 am

1 stop9h 24m

Panama City Tocumen Intl

sáb. 4/18

7:55 am-9:59 pm

1 stop13h 04m

$390

CharlestonPanama City

CHS - PTY

CHSPTY

Charleston

sáb. 3/14

7:02 pm-2:22 pm

2 stops20h 20m

Panama City Tocumen Intl

mar. 3/17

1:44 pm-10:17 am

2 stops19h 33m

$394

CharlestonPanama City

CHS - PTY

CHSPTY

Charleston

jue. 1/22

7:42 pm-3:38 pm

2 stops19h 56m

Panama City Tocumen Intl

lun. 1/26

2:27 pm-11:58 pm

1 stop9h 31m

$394

CharlestonPanama City

CHS - PTY

CHSPTY

Charleston

lun. 1/5

6:30 am-7:38 pm

1 stop13h 08m

Panama City Tocumen Intl

mar. 1/13

4:41 pm-4:17 pm

1 stop23h 36m

$443

CharlestonPanama City

CHS - PTY

CHSPTY

Charleston

mar. 4/14

6:31 pm-12:15 pm

2 stops18h 44m

Panama City Tocumen Intl

sáb. 4/18

1:55 pm-10:59 am

2 stops20h 04m

$443

CharlestonPanama City

CHS - PTY

CHSPTY

Charleston

mar. 2/24

5:27 am-1:50 pm

1 stop8h 23m

$152

CharlestonPanama City

CHS - PTY

CHSPTY

Charleston

mar. 2/24

5:06 pm-1:50 pm

2 stops20h 44m

$211

CharlestonPanama City

CHS - PTY

CHSPTY

Charleston

mar. 2/24

5:00 pm-8:50 am

3 stops39h 50m

$219

Flights are sorted by cheapest round-trip flights first.

Deals found on 12/22

Best time to book a flight from Charleston to Panama

Have a flexible travel schedule? Discover the best time to fly to Panama from Charleston with our price prediction graph.
Estimated round-trip price
Rates are based on past data. Find the cheapest month and day to book your flight based on your travel requirements, then search for cheap deals.

Cheapflights Insights

Everything you need to know about your flight from Charleston to Panama

What is the cheapest month to book a flight from Charleston to Panama?

Currently, July is the cheapest month in which you can book a flight from Charleston to Panama (average of $230). Flying from Charleston to Panama in April is currently the most expensive (average of $508). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.

What is the cheapest time of day to fly from CHS to PA?

Find hourly flight availability from Charleston to Panama. Discover flight options and departure times throughout the day, allowing you to choose a departure time that suits your schedule. Data last updated diciembre 23, 2025.

It’s optimal to fly from Charleston to Panama at noon. By choosing this option you can save up to 42% on the cost of your flight, compared to a flight in the evening.

Reviews of airlines servicing Panama

Get insights into the airlines that provide service to Panama. Read reviews, discover amenities, and learn about the overall travel experience offered by airlines. Use this information to make informed decisions when choosing an airline for your flight to Panama. Reviews last updated diciembre 23, 2025.
Get a feel of what it's like to fly with Delta, United Airlines, and American Airlines from Charleston to Panama by reading reviews from past customers. Users have also rated airlines in terms of entertainment options, comfort, food, crew/service, and boarding process.

Boarding

8.1

Crew

8.5

Comfort

7.9

Food

7.3

Overall

7.9

Entertainment

7.9

Reviews

1 / 20
6.0
Good

Jim,Nov 2025

AVL - ATL

The exit row seats without a seat in front are great for leg room but don’t have a fold out entertainment console so you’re forced to use the screen several feet in front of you (there is, at least, a remote). Best to bring a tablet loaded with entertainment or a book.

Boarding

8.1

Crew

8.5

Comfort

7.9

Food

7.3

Overall

7.9

Entertainment

7.9

Reviews

1 / 20
6.0
Good

Jim,Nov 2025

AVL - ATL

The exit row seats without a seat in front are great for leg room but don’t have a fold out entertainment console so you’re forced to use the screen several feet in front of you (there is, at least, a remote). Best to bring a tablet loaded with entertainment or a book.

Boarding

8.1

Crew

8.5

Comfort

7.9

Food

7.3

Overall

7.9

Entertainment

7.9

Reviews

1 / 20
6.0
Good

Jim,Nov 2025

AVL - ATL

The exit row seats without a seat in front are great for leg room but don’t have a fold out entertainment console so you’re forced to use the screen several feet in front of you (there is, at least, a remote). Best to bring a tablet loaded with entertainment or a book.

Boarding

8.1

Crew

8.5

Comfort

7.9

Food

7.3

Overall

7.9

Entertainment

7.9

Reviews

1 / 20
6.0
Good

Jim,Nov 2025

AVL - ATL

The exit row seats without a seat in front are great for leg room but don’t have a fold out entertainment console so you’re forced to use the screen several feet in front of you (there is, at least, a remote). Best to bring a tablet loaded with entertainment or a book.

Related info for your journey

Find useful and relevant information for your journey from Charleston to Panama. Access travel guides, tips, and recommendations to enhance your travel experience. Get information about local attractions, weather, transportation options, and more.
  • What airport do you fly from for flights from Charleston to Panama?

    For a flight from Charleston to Panama, you will be flying from Charleston. Charleston (CHS) is just 10.2 mi from the center of the city.

  • How long is the flight from Charleston to Panama?

    United Airlines and American Airlines can get you from Charleston to Panama in just under 9h 24m. Your travel time can differ by up to 10h 56m. Airlines will cover a distance of 1645 mi. Both multi-stop and nonstop flights can be found to your destination and back.

  • Can I find deals for flights from Charleston to Panama that include hotel bookings?

    Yes. In addition to deals on Charleston to Panama flights, Cheapflights offers vacation packages that include both flights and hotel.

  • How can I find direct flights from Charleston to Panama?

    After entering your origin and destination, apply the non-stop filter on the search result page to find direct flights from Charleston to Panama.

  • Can I find deals for business class flights from Charleston to Panama?

    Yes. Cheapflights offers flight deals from Charleston to Panama by cabin class. In addition to browsing deals, you can also filter by cabin class on the search results page after making a search.

  • What is the cheapest month to book a flight from Charleston to Panama?

    Currently, July is the cheapest month in which you can book a flight from Charleston to Panama (average of $230). Flying from Charleston to Panama in April is currently the most expensive (average of $508). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.

See more FAQs

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Alternative routes for Charleston to Panama

See prices for flight routes from nearby airports that may be better suited for you.

Top 3 airlines flying from Charleston to Panama

Discover the top 3 airlines that operate flights from Charleston to Panama. Compare their services, reliability, and customer satisfaction ratings to choose the airline that best suits your travel preferences and needs. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated diciembre 23, 2025.
AirlineCheapestAverageFlexibilityOn-time
DeltaCheapest$349Average$469FlexibilityNo cancel feeOn-timeN/A
American AirlinesCheapest$363Average$526FlexibilityNo cancel feeOn-time71%
United AirlinesCheapest$369Average$473FlexibilityNo cancel feeOn-time69%

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