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$470+ Cheap flights from Biloxi, MS to Panama

This is the cheapest round-trip flight price found by a Cheapflights user in the last 72 hours by searching for a flight departing on 2/23. Fares are subject to change and may not be available on all flights or dates of travel.
MSY — PTY
ene. 29 — feb. 51
jue. 1/29
jue. 2/5
1 adult, Economy
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Cheap flight deals from Biloxi to Panama

Best flights from Biloxi to Panama
Discover carefully curated flight deals from Biloxi to Panama that have cost, travel time, and layovers in mind to ensure you get the best travel experience. Data last updated diciembre 30, 2025.

This United Airlines deal was found by Cheapflights users on 12/27. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
lun. 2/234:55 pmGPT - PTY
1 stop25h 43mUnited Airlines
vie. 2/274:41 pmPTY - GPT
1 stop27h 53mUnited Airlines
Deal found 12/27$470
This American Airlines deal was found by Cheapflights users on 12/29. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
vie. 1/236:33 pmGPT - PTY
2 stops17h 54mAmerican Airlines
vie. 1/304:50 pmPTY - GPT
2 stops26h 13mAmerican Airlines
Deal found 12/29$520
This United Airlines deal was found by Cheapflights users on 12/28. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
jue. 2/267:05 amGPT - PTY
1 stop9h 02mUnited Airlines
jue. 3/511:35 amPTY - GPT
1 stop9h 10mUnited Airlines
Deal found 12/28$491
This United Airlines deal was found by Cheapflights users on 12/29. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
vie. 1/235:13 pmGPT - PTY
1 stop25h 25mUnited Airlines
vie. 1/308:55 amPTY - GPT
1 stop11h 53mUnited Airlines
Deal found 12/29$544
This United Airlines deal was found by Cheapflights users on 12/28. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
mié. 2/115:13 pmGPT - PTY
1 stop20h 32mUnited Airlines
mié. 2/184:41 pmPTY - GPT
1 stop21h 39mUnited Airlines
Deal found 12/28$598

Find flight deals from Biloxi to Panama

Keep the following information in mind while searching for Biloxi to Panama flight deals. Data was last updated diciembre 30, 2025.

Most accurate provider

eDreams
3 stars

Most trusted provider

eDreams
3 stars

Round-trip from

$470
(United Airlines)

Popular in

December

Cheapest in

April

Average price

$983
Provider with most accurate pricing for Gulfport Biloxi Regional-Panama City Tocumen Intl flight deals.
Search Deals
Provider most trusted by Cheapflights users for Gulfport Biloxi Regional-Panama City Tocumen Intl flights.
Search Deals
From Biloxi to Panama
Search Deals
Highest demand for flights based on searches. 21% potential increase in price ($189 potential increase over avg. RT price).
Search Deals
Cheapest flight prices on average. 5% potential price decrease ($34 potential savings vs. average RT price).
Search Deals
Average for round-trip flights in December 2025
Search Deals

Cheapflights Fare Finder

 
Customize your flight search to find flights from Biloxi to Panama that fit within your specific budget. Explore options based on user searches and filter the results based on your desired price range. Find flights that match your budget for a cost-effective journey. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated diciembre 30, 2025.
Use the filters below to find and compare flights from Biloxi to Panama that are best for you.

Fly from

Biloxi

Fly to

Panama

Route

Depart

Return

Price

GulfportPanama City

GPT - PTY

GPTPTY

Gulfport Biloxi Regional

lun. 2/23

4:55 pm-7:38 pm

1 stop25h 43m

Panama City Tocumen Intl

vie. 2/27

4:41 pm-7:34 pm

1 stop27h 53m

$470

GulfportPanama City

GPT - PTY

GPTPTY

Gulfport Biloxi Regional

jue. 2/26

7:05 am-5:07 pm

1 stop9h 02m

Panama City Tocumen Intl

jue. 3/5

11:35 am-7:45 pm

1 stop9h 10m

$491

GulfportPanama City

GPT - PTY

GPTPTY

Gulfport Biloxi Regional

vie. 1/23

6:33 pm-1:27 pm

2 stops17h 54m

Panama City Tocumen Intl

vie. 1/30

4:50 pm-6:03 pm

2 stops26h 13m

$520

GulfportPanama City

GPT - PTY

GPTPTY

Gulfport Biloxi Regional

vie. 1/23

5:13 pm-7:38 pm

1 stop25h 25m

Panama City Tocumen Intl

vie. 1/30

8:55 am-7:48 pm

1 stop11h 53m

$544

GulfportPanama City

GPT - PTY

GPTPTY

Gulfport Biloxi Regional

mié. 2/11

5:13 pm-2:45 pm

1 stop20h 32m

Panama City Tocumen Intl

mié. 2/18

4:41 pm-1:20 pm

1 stop21h 39m

$598

Flights are sorted by cheapest round-trip flights first.

Deals found on 12/27

Best time to book a flight from Biloxi to Panama

Have a flexible travel schedule? Discover the best time to fly to Panama from Biloxi with our price prediction graph.
Estimated round-trip price
Rates are based on past data. Find the cheapest month and day to book your flight based on your travel requirements, then search for cheap deals.

Cheapflights Insights

Everything you need to know about your flight from Biloxi to Panama

What is the cheapest month to book a flight from Biloxi to Panama?

Currently, September is the cheapest month in which you can book a flight from Biloxi to Panama (average of $346). Flying from Biloxi to Panama in January is currently the most expensive (average of $487). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.

Reviews of airlines servicing Panama

Get insights into the airlines that provide service to Panama. Read reviews, discover amenities, and learn about the overall travel experience offered by airlines. Use this information to make informed decisions when choosing an airline for your flight to Panama. Reviews last updated diciembre 30, 2025.
Read through reviews of airlines operating flights from Biloxi to Panama, such as United Airlines. Reviews also offer insight into each airline's entertainment options, comfort, food, crew/service, and boarding process.
United Airlines
7.4
Good
9,122 reviews

Crew

8.1

Overall

7.4

Food

6.6

Boarding

7.7

Comfort

7.3

Entertainment

7.1

Reviews

1 / 20
10.0
Excellent

Michelle,Dec 2025

DEN - MKE

I liked that the plane waited 5 minutes for a family whose incoming plane was late. This was the last flight of the day to MKE. Flight attendants actually checked in throughout the flight. Although, not really friendly. Happy to see screens on seat backs again. This is my first time not flying first class in over 10 years. It was economy plus.
United Airlines
7.4
Good
9,122 reviews
United Airlines
7.4
Good
9,122 reviews

Crew

8.1

Overall

7.4

Food

6.6

Boarding

7.7

Comfort

7.3

Entertainment

7.1

Reviews

1 / 20
10.0
Excellent

Michelle,Dec 2025

DEN - MKE

I liked that the plane waited 5 minutes for a family whose incoming plane was late. This was the last flight of the day to MKE. Flight attendants actually checked in throughout the flight. Although, not really friendly. Happy to see screens on seat backs again. This is my first time not flying first class in over 10 years. It was economy plus.

Related info for your journey

Find useful and relevant information for your journey from Biloxi to Panama. Access travel guides, tips, and recommendations to enhance your travel experience. Get information about local attractions, weather, transportation options, and more.

  • How long is the flight from Biloxi to Panama?

    Departing from Biloxi to Panama will take you 17h 54m. There are 1600 mi between Biloxi and Panama. Both multi-stop and nonstop flights can be found to your destination and back.

  • Can I find deals for flights from Biloxi to Panama that include hotel bookings?

    Yes. In addition to deals on Biloxi to Panama flights, Cheapflights offers vacation packages that include both flights and hotel.

  • How can I find direct flights from Biloxi to Panama?

    After entering your origin and destination, apply the non-stop filter on the search result page to find direct flights from Biloxi to Panama.

  • Can I find deals for business class flights from Biloxi to Panama?

    Yes. Cheapflights offers flight deals from Biloxi to Panama by cabin class. In addition to browsing deals, you can also filter by cabin class on the search results page after making a search.

  • What is the cheapest month to book a flight from Biloxi to Panama?

    Currently, September is the cheapest month in which you can book a flight from Biloxi to Panama (average of $346). Flying from Biloxi to Panama in January is currently the most expensive (average of $487). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.

See more FAQs

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Alternative routes for Biloxi to Panama

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Top 3 airlines flying from Biloxi to Panama

Discover the top 3 airlines that operate flights from Biloxi to Panama. Compare their services, reliability, and customer satisfaction ratings to choose the airline that best suits your travel preferences and needs. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated diciembre 30, 2025.
AirlineCheapestAverageFlexibilityOn-time
American AirlinesCheapest$385Average$433FlexibilityNo cancel feeOn-time71%
United AirlinesCheapest$391Average$533FlexibilityNo cancel feeOn-time69%
DeltaCheapest$411Average$521FlexibilityNo cancel feeOn-timeN/A

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