In terms of precipitation, rainfall in Panama ranges from 0.4 - 13.4 inches per month. October is typically the wettest month, when rainfall can reach 13.4 in. February is typically the driest time to visit Panama when rainfall is around 0.4 in.

If weather is an important factor for your trip to Panama, use this chart to help with planning. For those seeking warmer temperatures, February is the ideal time of year to visit, when temperatures reach an average of 80.6 F. Travelers looking to avoid the cold should look outside of January, when temperatures are typically at their lowest (around 78.8 F).

Can I find deals for flights from Biloxi to Panama that include hotel bookings?

Yes. In addition to deals on Biloxi to Panama flights, Cheapflights offers vacation packages that include both flights and hotel.

How can I find direct flights from Biloxi to Panama?

After entering your origin and destination, apply the non-stop filter on the search result page to find direct flights from Biloxi to Panama.

Can I find deals for business class flights from Biloxi to Panama?

Yes. Cheapflights offers flight deals from Biloxi to Panama by cabin class. In addition to browsing deals, you can also filter by cabin class on the search results page after making a search.

Find Cheap Flights from Biloxi to Panama

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Cheap flight deals from Biloxi to Panama

Most accurate provider	eDreams 3 stars
Most trusted provider	eDreams 3 stars
Popular in	December
Cheapest in	April
Average price	$775

Provider with most accurate pricing for Gulfport Biloxi Regional-Panama City Tocumen Intl flight deals.

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Provider most trusted by Cheapflights users for Gulfport Biloxi Regional-Panama City Tocumen Intl flights.

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Highest demand for flights based on searches. 17% potential increase in price ($151 potential increase over avg. RT price).

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Cheapest flight prices on average. 4% potential price decrease ($29 potential savings vs. average RT price).

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Average for round-trip flights in November 2025

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Cheapflights Insights

Everything you need to know about your flight from Biloxi to Panama

What is the cheapest month to book a flight from Biloxi to Panama?

Currently, September is the cheapest month in which you can book a flight from Biloxi to Panama (average of $346). Flying from Biloxi to Panama in January is currently the most expensive (average of $466). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.

What is the cheapest time of day to fly from B1L to PA?

One of the essential ways to save on airfare from Biloxi to Panama is to remain as flexible as possible. Flights that are in the morning tend to be the most expensive. A flight at noon could potentially save you up to 32% on airfare.

Reviews of airlines servicing Panama

Read through reviews of airlines operating flights from Biloxi to Panama, such as United Airlines. Reviews also offer insight into each airline's entertainment options, comfort, food, crew/service, and boarding process.

United Airlines

7.4

Good

8,997 reviews

Reviews

1 / 20

2.0

Mediocre

Sebrena,Oct 2025

IAH - RSW

The worst that I have ever experienced in my life so bad if it was free I'm not ever going to use your Airline again I dont believe ..... very disappointed 😞 😔0000000000000

United Airlines

7.4

Good

8,997 reviews

United Airlines

7.4

Good

8,997 reviews

Reviews

1 / 20

2.0

Mediocre

Sebrena,Oct 2025

IAH - RSW

The worst that I have ever experienced in my life so bad if it was free I'm not ever going to use your Airline again I dont believe ..... very disappointed 😞 😔0000000000000

Related info for your journey

Can I find deals for flights from Biloxi to Panama that include hotel bookings?
Yes. In addition to deals on Biloxi to Panama flights, Cheapflights offers vacation packages that include both flights and hotel.
How can I find direct flights from Biloxi to Panama?
After entering your origin and destination, apply the non-stop filter on the search result page to find direct flights from Biloxi to Panama.
Can I find deals for business class flights from Biloxi to Panama?
Yes. Cheapflights offers flight deals from Biloxi to Panama by cabin class. In addition to browsing deals, you can also filter by cabin class on the search results page after making a search.
What is the cheapest month to book a flight from Biloxi to Panama?
Currently, September is the cheapest month in which you can book a flight from Biloxi to Panama (average of $346). Flying from Biloxi to Panama in January is currently the most expensive (average of $466). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.

See more FAQs

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Alternative routes for Biloxi to Panama

Top 3 airlines flying from Biloxi to Panama

Airline	Cheapest	Average	Flexibility	On-time
American Airlines	Cheapest$385	Average$489	FlexibilityNo cancel fee	On-time71%
United Airlines	Cheapest$391	Average$535	FlexibilityNo cancel fee	On-time69%
Delta	Cheapest$411	Average$526	FlexibilityNo cancel fee	On-timeN/A

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Cheap flights from Biloxi, MS to Panama

Find cheap flights from Biloxi to Panama with Cheapflights

1. Tell us where you want to go

2. Select your favorite providers

3. Compare prices and book

Cheap flight deals from Biloxi to Panama

Keep the following information in mind while searching for Biloxi to Panama flight deals. Data was last updated November 2, 2025.

Most accurate provider

Most trusted provider

Popular in

Cheapest in

Average price

Cheapflights Insights

Everything you need to know about your flight from Biloxi to Panama

What is the cheapest month to book a flight from Biloxi to Panama?

What is the cheapest time of day to fly from B1L to PA?

Reviews of airlines servicing Panama

Read through reviews of airlines operating flights from Biloxi to Panama, such as United Airlines. Reviews also offer insight into each airline's entertainment options, comfort, food, crew/service, and boarding process.

Related info for your journey

Find useful and relevant information for your journey from Biloxi to Panama. Access travel guides, tips, and recommendations to enhance your travel experience. Get information about local attractions, weather, transportation options, and more.

Can I find deals for flights from Biloxi to Panama that include hotel bookings?

How can I find direct flights from Biloxi to Panama?

Can I find deals for business class flights from Biloxi to Panama?

What is the cheapest month to book a flight from Biloxi to Panama?

Browse thousands of different options on Cheapflights for your next trip

Toggle through the tabs below to find thousands of options on Cheapflights for your next trip.

Alternative routes for Biloxi to Panama

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Top 3 airlines flying from Biloxi to Panama

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