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$481+ Cheap flights from Roanoke (ROA) to Panama City (PTY)

This is the cheapest round-trip flight price found by a Cheapflights user in the last 72 hours by searching for a flight departing on 10/24. Fares are subject to change and may not be available on all flights or dates of travel.
ROA — PTY
Feb 26 — Mar 51
Thu 2/26
Thu 3/5
1 adult, Economy
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Cheap flight deals from Roanoke to Panama City

Cheapest flights from Roanoke to Panama City
Explore the most affordable flight options available from Roanoke to Panama City. Find the lowest fares from popular airlines and budget airlines, with prices last updated on January 27, 2026.

This United Airlines deal was found by Cheapflights users on 1/26. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 10/247:00 am
ROA
-
PTY
2 stops12h 37m
United Airlines
Wed 10/287:55 am
PTY
-
ROA
2 stops26h 51m
United Airlines
Deal found 1/26$481
This United Airlines deal was found by Cheapflights users on 1/27. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 4/117:59 pm
ROA
-
PTY
2 stops19h 15m
United Airlines
Sun 4/1910:00 am
PTY
-
ROA
2 stops22h 49m
United Airlines
Deal found 1/27$501
This United Airlines deal was found by Cheapflights users on 1/26. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 1/3112:40 pm
ROA
-
PTY
2 stops28h 27m
United Airlines
Sun 3/14:41 pm
PTY
-
ROA
2 stops17h 27m
United Airlines
Deal found 1/26$542
This Delta deal was found by Cheapflights users on 1/27. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 4/116:00 am
ROA
-
PTY
1 stop8h 03m
Delta
Sun 4/192:27 pm
PTY
-
ROA
1 stop8h 58m
Delta
Deal found 1/27$577
This Ovago deal was found by Cheapflights users on 1/25. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Ovago is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 3/27:59 pm
ROA
-
PTY
1 stop17h 51m
LATAM Airlines
Wed 4/292:20 pm
PTY
-
ROA
1 stop9h 03m
LATAM Airlines
Deal found 1/25$629
This Delta deal was found by Cheapflights users on 1/25. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 1/316:00 am
ROA
-
PTY
1 stop7h 55m
Delta
Sun 3/13:15 pm
PTY
-
ROA
1 stop8h 51m
Delta
Deal found 1/25$923
This Ovago deal was found by Cheapflights users on 1/25. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Ovago is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 3/27:59 pm
ROA
-
PTY
1 stop17h 51m
Multiple Airlines
Wed 4/2910:55 pm
PTY
-
ROA
2 stops19h 15m
Multiple Airlines
Deal found 1/25$2,047
This American Airlines deal was found by Cheapflights users on 1/25. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 3/28:00 pm
ROA
-
PTY
3 stops17h 40m
American Airlines
Wed 4/291:49 pm
PTY
-
ROA
2 stops21h 44m
American Airlines
Deal found 1/25$2,301
This American Airlines deal was found by Cheapflights users on 1/27. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 4/117:45 pm
ROA
-
PTY
3 stops17h 51m
American Airlines
Sun 4/191:49 pm
PTY
-
ROA
2 stops17h 47m
American Airlines
Deal found 1/27$2,306

Find flight deals from Roanoke to Panama City

Discover tips and strategies to find the most affordable flight options for your journey from Roanoke (ROA) to Panama City (PTY). Learn about various techniques such as flexible date searches, comparing prices across and setting up price alerts. Use these methods to find the cheapest flights available for your travel needs. Data last updated January 27, 2026.

Most accurate provider

FlightHub
3 stars

Most trusted provider

FlightHub
3 stars

Round-trip from

$481
(United Airlines)
Provider with most accurate pricing for Roanoke-Panama City Tocumen Intl flight deals.
Search Deals
Provider most trusted by Cheapflights users for Roanoke-Panama City Tocumen Intl flights.
Search Deals
From Roanoke to Panama City Tocumen Intl
Search Deals

Cheapflights Fare Finder

 
Customize your flight search to find flights from Roanoke to Panama City that fit within your specific budget. Explore options based on user searches and filter the results based on your desired price range. Find flights that match your budget for a cost-effective journey. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated January 27, 2026.
Use the filters below to find and compare flights from Roanoke to Panama City that are best for you.

Fly from

Roanoke

Fly to

Panama City

Route

Depart

Return

Price

RoanokePanama City

ROA - PTY

ROAPTY

Roanoke

Mon 3/2

5:33 pm-7:38 pm

2 stops26h 05m

Panama City Tocumen Intl

Wed 4/29

7:55 am-9:57 am

2 stops25h 02m

$481

RoanokePanama City

ROA - PTY

ROAPTY

Roanoke

Sat 4/11

7:59 pm-2:14 pm

2 stops19h 15m

Panama City Tocumen Intl

Sun 4/19

10:00 am-9:49 am

2 stops22h 49m

$501

RoanokePanama City

ROA - PTY

ROAPTY

Roanoke

Sat 4/11

6:00 am-1:03 pm

1 stop8h 03m

Panama City Tocumen Intl

Sun 4/19

2:27 pm-12:25 am

1 stop8h 58m

$577

RoanokePanama City

ROA - PTY

ROAPTY

Roanoke

Mon 3/2

7:59 pm-1:50 pm

1 stop17h 51m

Panama City Tocumen Intl

Wed 4/29

2:20 pm-12:23 am

1 stop9h 03m

$629

RoanokePanama City

ROA - PTY

ROAPTY

Roanoke

Mon 3/2

7:59 pm-1:50 pm

1 stop17h 51m

Panama City Tocumen Intl

Wed 4/29

10:55 pm-7:10 pm

2 stops19h 15m

$2,047

RoanokePanama City

ROA - PTY

ROAPTY

Roanoke

Mon 3/2

8:00 pm-1:40 pm

3 stops17h 40m

Panama City Tocumen Intl

Wed 4/29

1:49 pm-12:33 pm

2 stops21h 44m

$2,301

RoanokePanama City

ROA - PTY

ROAPTY

Roanoke

Sat 4/11

5:00 am-12:36 pm

2 stops8h 36m

Panama City Tocumen Intl

Sun 4/19

9:13 am-7:10 pm

1 stop8h 57m

$5,309

Flights are sorted by cheapest round-trip flights first.

Deals found on 1/25

Compare providers for flights from Roanoke to Panama City

Provider information is updated monthly. Please note that these providers often have deals for this flight, but the availability may vary on a day-by-day basis on Cheapflights.
Use the table below to compare price accuracy, trust ratings, and cancellation policies for each provider offering flight deals from Roanoke to Panama City in January.
ProviderPrice AccuracyTrust Score*
ExpediaPrice Accuracy1 starTrust Score*3 stars
FlightHubPrice Accuracy3 starsTrust Score*3 stars

*The Trust Score is based on feedback from users after their booking experience. It measures overall satisfaction, helping us identify issues like hidden fees, problems during the ticketing process, and the quality of customer service. This score is our best indicator of the provider's quality and reliability.

  • Most accurate provider: When it comes to deals on Roanoke-Panama City flights, users find the pricing of FlightHub to be most consistent on Cheapflights vs. FlightHub Users can find the same prices on Roanoke-Panama City flight deals on Cheapflights vs. FlightHub >95% of the time. Price accuracy is based on data collected from Roanoke-Panama City flight searches over the past month and is updated monthly.
  • Most trusted provider: When it comes to deals on Roanoke-Panama City flights, Cheapflights users trust FlightHub the most. FlightHub has received a user feedback score of 3 out of 3 stars (3 being the best), meaning they have been trusted the most by Cheapflights users looking for Roanoke-Panama City flight deals. Provider user feedback score is based on Cheapflights searches over the past month and is updated monthly.

Best time to book a flight from Roanoke to Panama City

Have a flexible travel schedule? Discover the best time to fly to Panama City from Roanoke with our price prediction graph.
Estimated round-trip price
Rates are based on past data. Find the cheapest month and day to book your flight based on your travel requirements, then search for cheap deals.

Related info for your journey

Find useful and relevant information for your journey from Roanoke to Panama City. Access travel guides, tips, and recommendations to enhance your travel experience. Get information about local attractions, weather, transportation options, and more.

  • How long is the flight from Roanoke to Panama City?

    United Airlines and Delta can get you from Roanoke to Panama City in just under 8h 03m. Your travel time can differ by up to 18h 02m. The distance from Roanoke to Panama City is about 1951 mi. When browsing for deals, the options you’ll see will be for both nonstop flights and flights with stops.

  • Can I find deals for flights from Roanoke to Panama City that include hotel bookings?

    Yes. In addition to deals on Roanoke to Panama City flights, Cheapflights offers vacation packages that include both flights and hotel.

  • How can I find direct flights from Roanoke to Panama City?

    After entering your origin and destination, apply the non-stop filter on the search result page to find direct flights from Roanoke to Panama City.

  • Can I find deals for business class flights from Roanoke to Panama City?

    Yes. Cheapflights offers flight deals from Roanoke to Panama City by cabin class. In addition to browsing deals, you can also filter by cabin class on the search results page after making a search.

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