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$455+ Cheap flights from Roanoke (ROA) to Panama City (PTY)

This is the cheapest round-trip flight price found by a Cheapflights user in the last 72 hours by searching for a flight departing on 3/1. Fares are subject to change and may not be available on all flights or dates of travel.
ROA — PTY
Oct 11 — Oct 181
Sat 10/11
Sat 10/18
1 adult, Economy
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Cheap flight deals from Roanoke to Panama City

Discover tips and strategies to find the most affordable flight options for your journey from Roanoke (ROA) to Panama City (PTY). Learn about various techniques such as flexible date searches, comparing prices across and setting up price alerts. Use these methods to find the cheapest flights available for your travel needs. Data last updated September 11, 2025.

Round-trip from

$455
(Delta)
From Roanoke to Panama City Tocumen Intl
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Cheapest flights from Roanoke to Panama City
Explore the most affordable flight options available from Roanoke to Panama City. Find the lowest fares from popular airlines and budget airlines, with prices last updated on September 11, 2025.

This Delta deal was found by Cheapflights users on 9/10. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 10/256:00 amROA - PTY
1 stop7h 56mDelta
Sat 11/12:21 pmPTY - ROA
1 stop8h 48mDelta
Deal found 9/10$515
This United Airlines deal was found by Cheapflights users on 9/10. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 10/257:30 pmROA - PTY
2 stops19h 15mUnited Airlines
Sat 11/13:41 pmPTY - ROA
2 stops20h 18mUnited Airlines
Deal found 9/10$517
This United Airlines deal was found by Cheapflights users on 9/11. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 9/187:35 pmROA - PTY
2 stops19h 39mUnited Airlines
Mon 9/223:30 pmPTY - ROA
2 stops28h 49mUnited Airlines
Deal found 9/11$522
This American Airlines deal was found by Cheapflights users on 9/11. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 12/268:00 pmROA - PTY
2 stops19h 54mAmerican Airlines
Mon 12/294:56 pmPTY - ROA
2 stops17h 36mAmerican Airlines
Deal found 9/11$716
This Kiwi.com deal was found by Cheapflights users on 9/11. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 10/239:20 pmROA - PTY
1 stop21h 20mMultiple Airlines
Sun 10/269:11 amPTY - ROA
1 stop10h 19mMultiple Airlines
Deal found 9/11$750
This Avianca deal was found by Cheapflights users on 9/10. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Avianca is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 10/77:30 pmROA - PTY
2 stops15h 55mMultiple Airlines
Mon 10/133:25 amPTY - ROA
2 stops18h 59mMultiple Airlines
Deal found 9/10$1,191
This Avianca deal was found by Cheapflights users on 9/11. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Avianca is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 10/237:30 pmROA - PTY
2 stops15h 55mAvianca
Sat 10/252:55 amPTY - ROA
2 stops14h 48mAvianca
Deal found 9/11$1,211
This Delta deal was found by Cheapflights users on 9/10. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 10/76:00 amROA - PTY
1 stop7h 56mDelta
Tue 10/142:21 pmPTY - ROA
1 stop8h 48mDelta
Deal found 9/10$1,260
This Delta deal was found by Cheapflights users on 9/11. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 12/266:00 amROA - PTY
1 stop14h 00mDelta
Mon 12/298:00 amPTY - ROA
1 stop16h 05mDelta
Deal found 9/11$1,749
This Avianca deal was found by Cheapflights users on 9/11. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Avianca is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 12/267:55 pmROA - PTY
2 stops14h 25mMultiple Airlines
Sun 12/282:55 amPTY - ROA
2 stops15h 56mMultiple Airlines
Deal found 9/11$2,140

Cheapflights Fare Finder

 
Customize your flight search to find flights from Roanoke to Panama City that fit within your specific budget. Explore options based on user searches and filter the results based on your desired price range. Find flights that match your budget for a cost-effective journey. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated September 11, 2025.
Use the filters below to find and compare flights from Roanoke to Panama City that are best for you.

Fly from

Roanoke

Fly to

Panama City

Route

Depart

Return

Price

RoanokePanama City

ROA - PTY

ROAPTY

Roanoke

Sun 3/1

6:00 am-2:02 pm

1 stop8h 02m

Panama City Tocumen Intl

Wed 4/8

2:20 pm-11:49 pm

1 stop8h 29m

$455

RoanokePanama City

ROA - PTY

ROAPTY

Roanoke

Sat 10/25

6:00 am-12:56 pm

1 stop7h 56m

Panama City Tocumen Intl

Sat 11/1

2:21 pm-12:09 am

1 stop8h 48m

$515

RoanokePanama City

ROA - PTY

ROAPTY

Roanoke

Sat 10/25

7:30 pm-1:45 pm

2 stops19h 15m

Panama City Tocumen Intl

Sat 11/1

3:41 pm-12:59 pm

2 stops20h 18m

$517

RoanokePanama City

ROA - PTY

ROAPTY

Roanoke

Tue 10/7

6:00 am-2:03 pm

2 stops9h 03m

Panama City Tocumen Intl

Tue 10/14

3:15 pm-2:22 pm

2 stops22h 07m

$522

RoanokePanama City

ROA - PTY

ROAPTY

Roanoke

Thu 10/23

7:30 pm-6:37 pm

2 stops24h 07m

Panama City Tocumen Intl

Sun 10/26

3:41 pm-11:59 am

2 stops19h 18m

$522

RoanokePanama City

ROA - PTY

ROAPTY

Roanoke

Sun 3/1

5:19 pm-3:00 pm

2 stops21h 41m

Panama City Tocumen Intl

Wed 4/8

1:55 pm-12:19 pm

2 stops21h 24m

$639

RoanokePanama City

ROA - PTY

ROAPTY

Roanoke

Fri 12/26

8:00 pm-3:54 pm

2 stops19h 54m

Panama City Tocumen Intl

Mon 12/29

2:53 pm-8:42 am

2 stops17h 49m

$716

RoanokePanama City

ROA - PTY

ROAPTY

Roanoke

Thu 10/23

9:20 pm-5:40 pm

1 stop21h 20m

Panama City Tocumen Intl

Sun 10/26

9:11 am-8:30 pm

1 stop10h 19m

$750

RoanokePanama City

ROA - PTY

ROAPTY

Roanoke

Tue 10/7

7:30 pm-10:25 am

2 stops15h 55m

Panama City Tocumen Intl

Mon 10/13

3:25 am-11:24 pm

2 stops18h 59m

$1,191

RoanokePanama City

ROA - PTY

ROAPTY

Roanoke

Thu 10/23

7:30 pm-10:25 am

2 stops15h 55m

Panama City Tocumen Intl

Sat 10/25

2:55 am-6:43 pm

2 stops14h 48m

$1,211

Flights are sorted by cheapest round-trip flights first.

Deals found on 9/11

Best time to book a flight from Roanoke to Panama City

Have a flexible travel schedule? Discover the best time to fly to Panama City from Roanoke with our price prediction graph.
Estimated round-trip price
Rates are based on past data. Find the cheapest month and day to book your flight based on your travel requirements, then search for cheap deals.

Cheapflights Insights

Everything you need to know about your flight from Roanoke to Panama City

What is the cheapest month to book a flight from Roanoke to Panama City?

Currently, October is the cheapest month in which you can book a flight from Roanoke to Panama City (average of $478). Flying from Roanoke to Panama City in December is currently the most expensive (average of $634). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.

What is the cheapest time of day to fly from ROA to PTY?

Find hourly flight availability from Roanoke to Panama City. Discover flight options and departure times throughout the day, allowing you to choose a departure time that suits your schedule. Data last updated September 11, 2025.

Regardless of the time of day you decide to fly, the ticket price will remain around the same. Book flights from Roanoke to Panama City as you normally would.

Related info for your journey

Find useful and relevant information for your journey from Roanoke to Panama City. Access travel guides, tips, and recommendations to enhance your travel experience. Get information about local attractions, weather, transportation options, and more.

  • How long is the flight from Roanoke to Panama City?

    Delta, United Airlines, and American Airlines can get you from Roanoke to Panama City in just under 8h 02m. Your travel time can differ by up to 11h 13m. The distance from Roanoke to Panama City is about 1951 mi. When browsing for deals, the options you’ll see will be for both nonstop flights and flights with stops.

  • Can I find deals for flights from Roanoke to Panama City that include hotel bookings?

    Yes. In addition to deals on Roanoke to Panama City flights, Cheapflights offers vacation packages that include both flights and hotel.

  • How can I find direct flights from Roanoke to Panama City?

    After entering your origin and destination, apply the non-stop filter on the search result page to find direct flights from Roanoke to Panama City.

  • Can I find deals for business class flights from Roanoke to Panama City?

    Yes. Cheapflights offers flight deals from Roanoke to Panama City by cabin class. In addition to browsing deals, you can also filter by cabin class on the search results page after making a search.

  • What is the cheapest month to book a flight from Roanoke to Panama City?

    Currently, October is the cheapest month in which you can book a flight from Roanoke to Panama City (average of $478). Flying from Roanoke to Panama City in December is currently the most expensive (average of $634). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.

See more FAQs

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