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Panama City

$501+ Cheap flights from Roanoke (ROA) to Panama City (PTY)

This is the cheapest round-trip flight price found by a Cheapflights user in the last 72 hours by searching for a flight departing on 11/21. Fares are subject to change and may not be available on all flights or dates of travel.
ROA — PTY
Nov 28 — Dec 51
Fri 11/28
Fri 12/5
1 adult, Economy
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Find flight deals from Roanoke to Panama City

Cheapest flights from Roanoke to Panama City
Explore the most affordable flight options available from Roanoke to Panama City. Find the lowest fares from popular airlines and budget airlines, with prices last updated on October 29, 2025.

This United Airlines deal was found by Cheapflights users on 10/26. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 11/2110:26 amROA - PTY
2 stops28h 19mUnited Airlines
Mon 12/14:41 pmPTY - ROA
2 stops26h 15mUnited Airlines
Deal found 10/26$501
This United Airlines deal was found by Cheapflights users on 10/27. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 11/37:50 pmROA - PTY
2 stops18h 05mUnited Airlines
Mon 11/104:41 pmPTY - ROA
2 stops19h 18mUnited Airlines
Deal found 10/27$521
This United Airlines deal was found by Cheapflights users on 10/28. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 12/1210:20 amROA - PTY
2 stops27h 35mUnited Airlines
Fri 12/198:55 amPTY - ROA
2 stops14h 35mUnited Airlines
Deal found 10/28$719
This Delta deal was found by Cheapflights users on 10/28. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 11/216:00 amROA - PTY
1 stop13h 59mDelta
Fri 12/53:46 pmPTY - ROA
1 stop8h 25mDelta
Deal found 10/28$760
This American Airlines deal was found by Cheapflights users on 10/28. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 11/2112:53 pmROA - PTY
2 stops24h 50mAmerican Airlines
Fri 12/52:50 pmPTY - ROA
2 stops17h 44mAmerican Airlines
Deal found 10/28$912
This Delta deal was found by Cheapflights users on 10/26. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 11/216:00 amROA - PTY
1 stop13h 59mDelta
Mon 12/13:37 pmPTY - ROA
1 stop8h 38mDelta
Deal found 10/26$1,129
This Avianca deal was found by Cheapflights users on 10/26. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Avianca is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 11/2110:26 amROA - PTY
2 stops14h 14mMultiple Airlines
Sun 11/302:55 amPTY - ROA
2 stops15h 48mMultiple Airlines
Deal found 10/26$2,219
This Avianca deal was found by Cheapflights users on 10/28. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Avianca is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 11/2110:26 amROA - PTY
2 stops14h 14mMultiple Airlines
Thu 12/42:55 amPTY - ROA
2 stops16h 01mMultiple Airlines
Deal found 10/28$3,992

Cheap flight deals from Roanoke to Panama City

Discover tips and strategies to find the most affordable flight options for your journey from Roanoke (ROA) to Panama City (PTY). Learn about various techniques such as flexible date searches, comparing prices across and setting up price alerts. Use these methods to find the cheapest flights available for your travel needs. Data last updated October 29, 2025.

Most accurate provider

FlightHub
3 stars

Most trusted provider

Expedia
3 stars

Round-trip from

$501
(United Airlines)
Provider with most accurate pricing for Roanoke-Panama City Tocumen Intl flight deals.
Search Deals
Provider most trusted by Cheapflights users for Roanoke-Panama City Tocumen Intl flights.
Search Deals
From Roanoke to Panama City Tocumen Intl
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Cheapflights Fare Finder

 
Customize your flight search to find flights from Roanoke to Panama City that fit within your specific budget. Explore options based on user searches and filter the results based on your desired price range. Find flights that match your budget for a cost-effective journey. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated October 29, 2025.
Use the filters below to find and compare flights from Roanoke to Panama City that are best for you.

Fly from

Roanoke

Fly to

Panama City

Route

Depart

Return

Price

RoanokePanama City

ROA - PTY

ROAPTY

Roanoke

Fri 11/21

10:26 am-2:45 pm

2 stops28h 19m

Panama City Tocumen Intl

Mon 12/1

4:41 pm-6:56 pm

2 stops26h 15m

$501

RoanokePanama City

ROA - PTY

ROAPTY

Roanoke

Fri 2/20

10:15 am-2:45 pm

2 stops28h 30m

Panama City Tocumen Intl

Fri 2/27

4:41 pm-10:13 am

2 stops17h 32m

$517

RoanokePanama City

ROA - PTY

ROAPTY

Roanoke

Fri 12/12

10:20 am-1:55 pm

2 stops27h 35m

Panama City Tocumen Intl

Fri 12/19

8:55 am-11:30 pm

2 stops14h 35m

$719

RoanokePanama City

ROA - PTY

ROAPTY

Roanoke

Fri 11/21

6:00 am-7:59 pm

1 stop13h 59m

Panama City Tocumen Intl

Fri 12/5

3:46 pm-12:11 am

1 stop8h 25m

$760

RoanokePanama City

ROA - PTY

ROAPTY

Roanoke

Fri 2/20

6:00 am-2:02 pm

1 stop8h 02m

Panama City Tocumen Intl

Fri 2/27

3:27 pm-11:49 pm

1 stop8h 22m

$778

RoanokePanama City

ROA - PTY

ROAPTY

Roanoke

Fri 11/21

12:53 pm-1:43 pm

2 stops24h 50m

Panama City Tocumen Intl

Fri 12/5

2:50 pm-8:34 am

2 stops17h 44m

$912

RoanokePanama City

ROA - PTY

ROAPTY

Roanoke

Fri 11/21

6:00 am-7:59 pm

1 stop13h 59m

Panama City Tocumen Intl

Mon 12/1

3:37 pm-12:15 am

1 stop8h 38m

$1,129

RoanokePanama City

ROA - PTY

ROAPTY

Roanoke

Fri 11/21

10:26 am-12:40 am

2 stops14h 14m

Panama City Tocumen Intl

Sun 11/30

2:55 am-6:43 pm

2 stops15h 48m

$2,219

RoanokePanama City

ROA - PTY

ROAPTY

Roanoke

Fri 2/20

6:00 am-3:14 pm

2 stops9h 14m

Panama City Tocumen Intl

Fri 2/27

4:04 pm-10:39 am

3 stops18h 35m

$2,281

Flights are sorted by cheapest round-trip flights first.

Deals found on 10/26

Compare providers for flights from Roanoke to Panama City

Provider information is updated monthly. Please note that these providers often have deals for this flight, but the availability may vary on a day-by-day basis on Cheapflights.
Use the table below to compare price accuracy, trust ratings, and cancellation policies for each provider offering flight deals from Roanoke to Panama City in October.
ProviderPrice AccuracyTrust Score*
ExpediaPrice Accuracy2 starsTrust Score*3 stars
FlightHubPrice Accuracy3 starsTrust Score*1 star

*The Trust Score is based on feedback from users after their booking experience. It measures overall satisfaction, helping us identify issues like hidden fees, problems during the ticketing process, and the quality of customer service. This score is our best indicator of the provider's quality and reliability.

  • Most accurate provider: When it comes to deals on Roanoke-Panama City flights, users find the pricing of FlightHub to be most consistent on Cheapflights vs. FlightHub Users can find the same prices on Roanoke-Panama City flight deals on Cheapflights vs. FlightHub >95% of the time. Price accuracy is based on data collected from Roanoke-Panama City flight searches over the past month and is updated monthly.
  • Most trusted provider: When it comes to deals on Roanoke-Panama City flights, Cheapflights users trust Expedia the most. Expedia has received a user feedback score of 3 out of 3 stars (3 being the best), meaning they have been trusted the most by Cheapflights users looking for Roanoke-Panama City flight deals. Provider user feedback score is based on Cheapflights searches over the past month and is updated monthly.

Best time to book a flight from Roanoke to Panama City

Have a flexible travel schedule? Discover the best time to fly to Panama City from Roanoke with our price prediction graph.
Estimated round-trip price
Rates are based on past data. Find the cheapest month and day to book your flight based on your travel requirements, then search for cheap deals.

Cheapflights Insights

Everything you need to know about your flight from Roanoke to Panama City

What is the cheapest month to book a flight from Roanoke to Panama City?

Currently, August is the cheapest month in which you can book a flight from Roanoke to Panama City (average of $234). Flying from Roanoke to Panama City in June is currently the most expensive (average of $615). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.

What is the cheapest time of day to fly from ROA to PTY?

Find hourly flight availability from Roanoke to Panama City. Discover flight options and departure times throughout the day, allowing you to choose a departure time that suits your schedule. Data last updated October 29, 2025.

It’s optimal to fly from Roanoke to Panama City in the evening. By choosing this option you can save up to 64% on the cost of your flight, compared to a flight at noon.

Related info for your journey

Find useful and relevant information for your journey from Roanoke to Panama City. Access travel guides, tips, and recommendations to enhance your travel experience. Get information about local attractions, weather, transportation options, and more.

  • How long is the flight from Roanoke to Panama City?

    United Airlines and Delta can get you from Roanoke to Panama City in just under 13h 59m. Your travel time can differ by up to 14h 20m. The distance from Roanoke to Panama City is about 1951 mi. When browsing for deals, the options you’ll see will be for both nonstop flights and flights with stops.

  • Can I find deals for flights from Roanoke to Panama City that include hotel bookings?

    Yes. In addition to deals on Roanoke to Panama City flights, Cheapflights offers vacation packages that include both flights and hotel.

  • How can I find direct flights from Roanoke to Panama City?

    After entering your origin and destination, apply the non-stop filter on the search result page to find direct flights from Roanoke to Panama City.

  • Can I find deals for business class flights from Roanoke to Panama City?

    Yes. Cheapflights offers flight deals from Roanoke to Panama City by cabin class. In addition to browsing deals, you can also filter by cabin class on the search results page after making a search.

  • What is the cheapest month to book a flight from Roanoke to Panama City?

    Currently, August is the cheapest month in which you can book a flight from Roanoke to Panama City (average of $234). Flying from Roanoke to Panama City in June is currently the most expensive (average of $615). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.

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