OR Tambo

$640+ Cheap flights from South Carolina to OR Tambo (JNB)

This is the cheapest one-way flight price found by a Cheapflights user in the last 72 hours by searching for a flight departing on 3/13. Fares are subject to change and may not be available on all flights or dates of travel.
CHS — JNB
Mar 7 — Mar 141
We work with more than 300 partners to bring you better travel deals

Find cheap flights from South Carolina to OR Tambo with Cheapflights

1. Tell us where you want to go

Enter your travel information like dates, passengers, trip type (one-way or round trip), and preferred cabin class then click “Find deals”

2. Select your favorite providers

We find the providers serving your travel needs. Choose up to four travel providers to compare side-by-side for flights, hotels, or car rentals.

3. Compare prices and book

Review each provider’s pricing and select the best option for you! Book through your favorite provider’s website for a seamless experience.

Cheap flight deals from South Carolina to OR Tambo

Cheapest flights from South Carolina to OR Tambo
Explore the most affordable flight options available from South Carolina to OR Tambo. Find the lowest fares from popular airlines and budget airlines, with prices last updated on February 5, 2026.

This Delta deal was found by Cheapflights users on 2/3. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 2/165:25 am
CLT
-
JNB
1 stop30h 35m
Delta
Tue 3/39:55 pm
JNB
-
CLT
2 stops27h 53m
Delta
Deal found 2/3$1,125
This Ovago deal was found by Cheapflights users on 2/4. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Ovago is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 4/14:52 pm
CLT
-
JNB
1 stop20h 48m
Kenya Airways
Wed 4/159:55 pm
JNB
-
CLT
1 stop28h 21m
Kenya Airways
Deal found 2/4$1,136
This Gurufare deal was found by Cheapflights users on 2/3. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Gurufare is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 11/126:00 am
CLT
-
JNB
2 stops24h 05m
Ethiopian Air
Thu 11/192:30 pm
JNB
-
CLT
3 stops30h 34m
Ethiopian Air
Deal found 2/3$1,140
This Ovago deal was found by Cheapflights users on 2/3. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Ovago is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 5/2111:58 am
CLT
-
JNB
1 stop25h 42m
SAUDIA
Mon 5/259:55 pm
JNB
-
CLT
1 stop21h 34m
SAUDIA
Deal found 2/3$1,144
This KAYAK deal was found by Cheapflights users on 2/4. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure KAYAK is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 7/610:07 am
CLT
-
JNB
1 stop27h 33m
Multiple Airlines
Thu 7/169:55 pm
JNB
-
CLT
1 stop21h 35m
Multiple Airlines
Deal found 2/4$1,146
This Virgin Atlantic deal was found by Cheapflights users on 2/2. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Virgin Atlantic is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 7/67:59 pm
CLT
-
JNB
1 stop17h 41m
Virgin Atlantic
Thu 7/169:55 pm
JNB
-
CLT
1 stop28h 26m
Virgin Atlantic
Deal found 2/2$1,147
This KLM deal was found by Cheapflights users on 2/4. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure KLM is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 11/112:59 pm
CLT
-
JNB
2 stops26h 06m
KLM
Fri 11/2011:59 pm
JNB
-
CLT
2 stops28h 51m
KLM
Deal found 2/4$1,163
This KLM deal was found by Cheapflights users on 2/4. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure KLM is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 3/82:30 pm
CLT
-
JNB
2 stops25h 35m
KLM
Mon 3/2311:59 pm
JNB
-
CLT
2 stops28h 39m
KLM
Deal found 2/4$1,164
This KLM deal was found by Cheapflights users on 2/2. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure KLM is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 11/1212:59 pm
CLT
-
JNB
2 stops26h 06m
KLM
Thu 11/1911:59 pm
JNB
-
CLT
2 stops28h 51m
KLM
Deal found 2/2$1,165
This Etihad Airways deal was found by Cheapflights users on 2/4. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Etihad Airways is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 8/277:00 am
CHS
-
JNB
2 stops43h 20m
Multiple Airlines
Thu 9/249:50 am
JNB
-
CHS
2 stops39h 19m
Multiple Airlines
Deal found 2/4$1,211
This American Airlines deal was found by Cheapflights users on 2/2. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 3/186:22 pm
GSP
-
JNB
2 stops34h 03m
American Airlines
Wed 3/2510:00 pm
JNB
-
GSP
2 stops28h 02m
American Airlines
Deal found 2/2$1,216
This American Airlines deal was found by Cheapflights users on 2/4. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 3/101:58 pm
MYR
-
JNB
2 stops35h 37m
American Airlines
Tue 3/2410:00 pm
JNB
-
MYR
2 stops30h 28m
American Airlines
Deal found 2/4$1,240

Find flight deals from South Carolina to OR Tambo

Keep the following information in mind while searching for South Carolina to OR Tambo flight deals. Data was last updated February 5, 2026.

Round-trip from

$1,125
(Delta)

One-way from

$640
(FlightHub)
From South Carolina to Johannesburg OR Tambo
One-way flight from South Carolina to Johannesburg OR Tambo

Cheapflights Fare Finder

 
Customize your flight search to find flights from South Carolina to OR Tambo that fit within your specific budget. Explore options based on user searches and filter the results based on your desired price range. Find flights that match your budget for a cost-effective journey. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated February 5, 2026.
Use the filters below to find and compare flights from South Carolina to Johannesburg OR Tambo Airport that are best for you.

Fly from

South Carolina

Fly to

OR Tambo

Route

Depart

Return

Price

CharlotteJohannesburg

CLT - JNB

CLTJNB

Charlotte Douglas

Mon 2/16

5:25 am-7:00 pm

1 stop30h 35m

Johannesburg OR Tambo

Tue 3/3

9:55 pm-6:48 pm

2 stops27h 53m

$1,125

CharlotteJohannesburg

CLT - JNB

CLTJNB

Charlotte Douglas

Mon 7/6

10:07 am-7:40 pm

1 stop27h 33m

Johannesburg OR Tambo

Thu 7/16

9:55 pm-1:30 pm

1 stop21h 35m

$1,146

CharlotteJohannesburg

CLT - JNB

CLTJNB

Charlotte Douglas

Mon 7/6

7:59 pm-7:40 pm

1 stop17h 41m

Johannesburg OR Tambo

Thu 7/16

9:55 pm-8:21 pm

1 stop28h 26m

$1,147

CharlotteJohannesburg

CLT - JNB

CLTJNB

Charlotte Douglas

Sun 3/8

2:30 pm-10:05 pm

2 stops25h 35m

Johannesburg OR Tambo

Mon 3/23

11:59 pm-10:38 pm

2 stops28h 39m

$1,164

CharlotteJohannesburg

CLT - JNB

CLTJNB

Charlotte Douglas

Sun 3/8

7:50 am-1:05 pm

2 stops23h 15m

Johannesburg OR Tambo

Mon 3/23

2:30 pm-2:11 pm

3 stops29h 41m

$1,164

CharlotteJohannesburg

CLT - JNB

CLTJNB

Charlotte Douglas

Wed 4/1

11:23 am-9:20 pm

2 stops27h 57m

Johannesburg OR Tambo

Wed 4/15

6:00 pm-4:26 pm

2 stops28h 26m

$1,164

CharlotteJohannesburg

CLT - JNB

CLTJNB

Charlotte Douglas

Tue 3/10

12:43 pm-10:05 pm

2 stops27h 22m

Johannesburg OR Tambo

Tue 3/17

7:20 pm-9:33 pm

2 stops32h 13m

$1,164

CharlotteJohannesburg

CLT - JNB

CLTJNB

Charlotte Douglas

Fri 2/27

10:32 am-10:05 pm

2 stops28h 33m

Johannesburg OR Tambo

Sun 3/8

7:20 pm-7:12 pm

2 stops29h 52m

$1,164

CharlotteJohannesburg

CLT - JNB

CLTJNB

Charlotte Douglas

Mon 3/30

3:26 pm-9:20 pm

2 stops23h 54m

Johannesburg OR Tambo

Wed 4/15

6:00 pm-4:26 pm

2 stops28h 26m

$1,166

GreenvilleJohannesburg

GSP - JNB

GSPJNB

Greenville

Wed 3/18

6:22 pm-10:25 am

2 stops34h 03m

Johannesburg OR Tambo

Wed 3/25

10:00 pm-8:02 pm

2 stops28h 02m

$1,216

Flights are sorted by cheapest round-trip flights first.

Deals found on 2/4

Showing 1-10 of 55 results
1
2
3
...
6

Best time to book a flight from South Carolina to OR Tambo

Have a flexible travel schedule? Discover the best time to fly to OR Tambo from South Carolina with our price prediction graph.
Estimated round-trip price
Rates are based on past data. Find the cheapest month and day to book your flight based on your travel requirements, then search for cheap deals.

Cheapflights Insights

Everything you need to know about your flight from South Carolina to Johannesburg OR Tambo Airport
No data available for this route at this time. Please check back soon.

Related info for your journey

Find useful and relevant information for your journey from South Carolina to OR Tambo. Access travel guides, tips, and recommendations to enhance your travel experience. Get information about local attractions, weather, transportation options, and more.
  • How long is the flight from South Carolina to Johannesburg OR Tambo Airport?

    Airlines like Delta, Virgin Atlantic, and American Airlines fly from South Carolina to Johannesburg OR Tambo Airport in about 17h 41m. The time it takes to get you to your destination can typically vary by up to 16h 22m. Airlines will cover a distance of 8263 mi. When browsing for deals, the options you’ll see will be for both nonstop flights and flights with stops.

  • What are the most popular routes from South Carolina to Johannesburg OR Tambo Airport?

  • Can I find deals for flights from South Carolina to OR Tambo that include hotel bookings?

    Yes. In addition to deals on South Carolina to OR Tambo flights, Cheapflights offers vacation packages that include both flights and hotel.

  • How can I find direct flights from South Carolina to OR Tambo?

    After entering your origin and destination, apply the non-stop filter on the search result page to find direct flights from South Carolina to OR Tambo.

  • Can I find deals for business class flights from South Carolina to OR Tambo?

    Yes. Cheapflights offers flight deals from South Carolina to OR Tambo by cabin class. In addition to browsing deals, you can also filter by cabin class on the search results page after making a search.

See more FAQs

Traveling to a place near Johannesburg OR Tambo Airport?

Book flights to Johannesburg OR Tambo Airport if you plan to visit one of these locations
Sandton
Kempton Park
Edenvale

Browse thousands of different options on Cheapflights for your next trip

Toggle through the tabs below to find thousands of options on Cheapflights for your next trip.

Alternative routes for South Carolina to OR Tambo

See prices for flight routes from nearby airports that may be better suited for you.

Top 2 airlines flying from South Carolina to OR Tambo

Discover the top 2 airlines that operate flights from South Carolina to OR Tambo. Compare their services, reliability, and customer satisfaction ratings to choose the airline that best suits your travel preferences and needs. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated February 5, 2026.
AirlineCheapestAverageFlexibilityOn-time
DeltaCheapest$1,032Average$1,682FlexibilityNo cancel feeOn-timeN/A
British AirwaysCheapest$1,183Average$1,188FlexibilityNo cancel feeOn-time70%

100% Free

Cheapflights is completely free to use, so you can start saving the moment you arrive.

Book with Flexibility

Our users can plan ahead with confidence and find flights with no change fees

Travel Smart

Millions of people come to us for their flight needs every year. We help make travel planning easy by providing useful insights and data-driven graphs that can inform your decisions.