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Panama City

$509+ Cheap flights from Spain to Panama City, FL (ECP)

This is the cheapest round-trip flight price found by a Cheapflights user in the last 72 hours by searching for a flight departing on 2/20. Fares are subject to change and may not be available on all flights or dates of travel.
MAD — ECP
Sep 8 — Sep 151
Mon 9/8
Mon 9/15
1 adult, Economy
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Cheap flight deals from Spain to Panama City

Keep the following information in mind while searching for Spain to Panama City flight deals. Data was last updated September 3, 2025.

Round-trip from

$509
(United Airlines)
From Spain to Panama City NW Florida Beaches
Search Deals

Find flight deals from Spain to Panama City

Cheapest flights from Spain to Panama City
Explore the most affordable flight options available from Spain to Panama City. Find the lowest fares from popular airlines and budget airlines, with prices last updated on September 3, 2025.

This American Airlines deal was found by Cheapflights users on 9/1. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 9/1711:50 amMAD - ECP
1 stop33h 30mAmerican Airlines
Sun 9/216:59 pmECP - MAD
1 stop27h 31mAmerican Airlines
Deal found 9/1$641
This United Airlines deal was found by Cheapflights users on 9/1. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 9/1712:45 pmMAD - ECP
2 stops28h 09mUnited Airlines
Sun 9/215:06 pmECP - MAD
2 stops31h 59mUnited Airlines
Deal found 9/1$701
This Delta deal was found by Cheapflights users on 9/1. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 9/1710:05 amMAD - ECP
1 stop12h 46mDelta
Sun 9/214:46 pmECP - MAD
2 stops19h 44mDelta
Deal found 9/1$826
This United Airlines deal was found by Cheapflights users on 9/1. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 12/611:15 amMAD - ECP
2 stops35h 56mUnited Airlines
Sun 1/49:52 amECP - MAD
2 stops39h 08mUnited Airlines
Deal found 9/1$921
This KLM deal was found by Cheapflights users on 9/1. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure KLM is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 9/46:00 amMAD - ECP
2 stops17h 17mKLM
Sat 9/139:13 amECP - MAD
1 stop17h 22mKLM
Deal found 9/1$974
This Delta deal was found by Cheapflights users on 9/1. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 9/41:05 pmMAD - ECP
2 stops17h 01mDelta
Sat 9/136:00 amECP - MAD
2 stops18h 50mDelta
Deal found 9/1$976
This KLM deal was found by Cheapflights users on 9/1. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure KLM is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 12/611:00 amMAD - ECP
2 stops18h 43mKLM
Sun 1/46:35 pmECP - MAD
1 stop31h 25mKLM
Deal found 9/1$993

Cheapflights Fare Finder

 
Customize your flight search to find flights from Spain to Panama City that fit within your specific budget. Explore options based on user searches and filter the results based on your desired price range. Find flights that match your budget for a cost-effective journey. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated September 3, 2025.
Use the filters below to find and compare flights from Spain to Panama City that are best for you.

Fly from

Spain

Fly to

Panama City

Route

Depart

Return

Price

MadridPanama City

MAD - ECP

MADECP

Madrid Barajas

Fri 2/20

11:15 am-11:52 am

2 stops31h 37m

Panama City NW Florida Beaches

Tue 2/24

9:00 am-9:15 am

2 stops17h 15m

$509

MadridPanama City

MAD - ECP

MADECP

Madrid Barajas

Wed 9/17

11:50 am-2:20 pm

1 stop33h 30m

Panama City NW Florida Beaches

Sun 9/21

6:59 pm-5:30 am

1 stop27h 31m

$641

MadridPanama City

MAD - ECP

MADECP

Madrid Barajas

Wed 9/17

12:45 pm-9:54 am

2 stops28h 09m

Panama City NW Florida Beaches

Sun 9/21

5:06 pm-8:05 am

2 stops31h 59m

$701

MadridPanama City

MAD - ECP

MADECP

Madrid Barajas

Fri 2/20

6:00 am-7:38 pm

2 stops20h 38m

Panama City NW Florida Beaches

Tue 2/24

9:23 am-9:00 am

1 stop16h 37m

$782

MadridPanama City

MAD - ECP

MADECP

Madrid Barajas

Wed 9/17

10:05 am-3:51 pm

1 stop12h 46m

Panama City NW Florida Beaches

Sun 9/21

4:46 pm-7:30 pm

2 stops19h 44m

$826

MadridPanama City

MAD - ECP

MADECP

Madrid Barajas

Wed 10/1

12:40 pm-9:12 pm

1 stop15h 32m

$802

MadridPanama City

MAD - ECP

MADECP

Madrid Barajas

Thu 10/2

1:00 pm-6:29 pm

1 stop12h 29m

$912

MadridPanama City

MAD - ECP

MADECP

Madrid Barajas

Tue 9/30

12:40 pm-9:12 pm

1 stop15h 32m

$912

MadridPanama City

MAD - ECP

MADECP

Madrid Barajas

Mon 9/29

4:20 pm-11:31 am

2 stops26h 11m

$917

MadridPanama City

MAD - ECP

MADECP

Madrid Barajas

Fri 10/3

12:40 pm-9:12 pm

1 stop15h 32m

$936

Flights are sorted by cheapest round-trip flights first.

Deals found on 8/31

Showing 1-10 of 11 results
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Best time to book a flight from Spain to Panama City

Have a flexible travel schedule? Discover the best time to fly to Panama City from Spain with our price prediction graph.
Estimated round-trip price
Rates are based on past data. Find the cheapest month and day to book your flight based on your travel requirements, then search for cheap deals.

Cheapflights Insights

Everything you need to know about your flight from Spain to Panama City

What is the cheapest month to book a flight from Spain to Panama City, Florida?

Currently, January is the cheapest month in which you can book a flight from Spain to Panama City, Florida (average of $346). Flying from Spain to Panama City, Florida in March is currently the most expensive (average of $460). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.

What is the cheapest time of day to fly from ES to ECP?

Find hourly flight availability from Spain to Panama City. Discover flight options and departure times throughout the day, allowing you to choose a departure time that suits your schedule. Data last updated September 3, 2025.

Regardless of the time of day you decide to fly, the ticket price will remain around the same. Book flights from Spain to Panama City, Florida as you normally would.

Related info for your journey

Find useful and relevant information for your journey from Spain to Panama City. Access travel guides, tips, and recommendations to enhance your travel experience. Get information about local attractions, weather, transportation options, and more.

  • What airport do you fly into for flights to Panama City from Spain?

    Panama City NW Florida Beaches (ECP) is the airport you will fly into if you book a flight from Spain to Panama City. It is only a 16.0 mi journey from NW Florida Beaches (ECP) to Panama City’s city center.

  • How long is the flight from Spain to Panama City, Florida?

    There are many flights that can get you from Spain to Panama City, Florida in 31h 37m. Fly via United Airlines or American Airlines to get the fastest option. The distance between Spain and Panama City, Florida is about 4513 mi. When browsing for deals, the options you’ll see will be for both nonstop flights and flights with stops.

  • Can I find deals for flights from Spain to Panama City that include hotel bookings?

    Yes. In addition to deals on Spain to Panama City flights, Cheapflights offers vacation packages that include both flights and hotel.

  • How can I find direct flights from Spain to Panama City?

    After entering your origin and destination, apply the non-stop filter on the search result page to find direct flights from Spain to Panama City.

  • Can I find deals for business class flights from Spain to Panama City?

    Yes. Cheapflights offers flight deals from Spain to Panama City by cabin class. In addition to browsing deals, you can also filter by cabin class on the search results page after making a search.

  • What is the cheapest month to book a flight from Spain to Panama City, Florida?

    Currently, January is the cheapest month in which you can book a flight from Spain to Panama City, Florida (average of $346). Flying from Spain to Panama City, Florida in March is currently the most expensive (average of $460). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.

See more FAQs

Traveling to a place near Panama City?

Book flights to Panama City if you plan to visit one of these locations
Mexico Beach

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