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Panama City

$547+ Cheap flights from Spain to Panama City, FL (ECP)

This is the cheapest one-way flight price found by a Cheapflights user in the last 72 hours by searching for a flight departing on 4/22. Fares are subject to change and may not be available on all flights or dates of travel.
MAD — ECP
Apr 9 — Apr 161
Thu 4/9
Thu 4/16
1 adult, Economy
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Cheap flight deals from Spain to Panama City

Cheapest flights from Spain to Panama City
Explore the most affordable flight options available from Spain to Panama City. Find the lowest fares from popular airlines and budget airlines, with prices last updated on March 10, 2026.

This United Airlines deal was found by Cheapflights users on 3/7. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 6/25:55 am
MAD
-
ECP
2 stops36h 07m
United Airlines
Mon 8/312:28 pm
ECP
-
MAD
2 stops18h 32m
United Airlines
Deal found 3/7$798
This United Airlines deal was found by Cheapflights users on 3/9. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 12/41:35 pm
MAD
-
ECP
2 stops33h 42m
United Airlines
Mon 12/76:40 am
ECP
-
MAD
2 stops19h 35m
United Airlines
Deal found 3/9$809
This Trip.com deal was found by Cheapflights users on 3/7. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Trip.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 6/29:50 am
MAD
-
ECP
1 stop20h 11m
Virgin Atlantic
Mon 8/314:10 pm
ECP
-
MAD
1 stop13h 05m
Virgin Atlantic
Deal found 3/7$842
This KLM deal was found by Cheapflights users on 3/7. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure KLM is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 6/29:50 am
MAD
-
ECP
1 stop13h 40m
KLM
Mon 8/319:23 am
ECP
-
MAD
2 stops13h 57m
KLM
Deal found 3/7$886
This American Airlines deal was found by Cheapflights users on 3/5. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 12/412:40 pm
MAD
-
ECP
1 stop18h 15m
American Airlines
Mon 12/72:43 pm
ECP
-
MAD
2 stops15h 52m
American Airlines
Deal found 3/5$960
This Delta deal was found by Cheapflights users on 3/5. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 5/179:50 am
MAD
-
ECP
1 stop16h 19m
Delta
Sat 5/237:41 am
ECP
-
MAD
1 stop21h 34m
Delta
Deal found 3/5$968

Find flight deals from Spain to Panama City

Keep the following information in mind while searching for Spain to Panama City flight deals. Data was last updated March 10, 2026.

Round-trip from

$798
(United Airlines)

One-way from

$547
(Kiwi.com)
From Spain to Panama City NW Florida Beaches
Search Deals
One-way flight from Spain to Panama City NW Florida Beaches
Search Deals

Cheapflights Fare Finder

 
Customize your flight search to find flights from Spain to Panama City that fit within your specific budget. Explore options based on user searches and filter the results based on your desired price range. Find flights that match your budget for a cost-effective journey. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated March 10, 2026.
Use the filters below to find and compare flights from Spain to Panama City that are best for you.

Fly from

Fly to

Route

Depart

Return

Price

Cheapest round-trip

MadridPanama City

MAD - ECP

MADECP

Madrid Barajas

Tue 6/2

5:55 am-11:02 am

2 stops36h 07m

Panama City NW Florida Beaches

Mon 8/31

2:28 pm-4:00 pm

2 stops18h 32m

$798

MadridPanama City

MAD - ECP

MADECP

Madrid Barajas

Tue 6/2

9:50 am-11:01 pm

1 stop20h 11m

Panama City NW Florida Beaches

Mon 8/31

4:10 pm-12:15 pm

1 stop13h 05m

$842

MadridPanama City

MAD - ECP

MADECP

Madrid Barajas

Tue 6/2

9:50 am-4:30 pm

1 stop13h 40m

Panama City NW Florida Beaches

Mon 8/31

9:23 am-6:20 am

2 stops13h 57m

$886

MadridPanama City

MAD - ECP

MADECP

Madrid Barajas

Sun 5/17

9:50 am-7:09 pm

1 stop16h 19m

Panama City NW Florida Beaches

Sat 5/23

7:41 am-12:15 pm

1 stop21h 34m

$968
Quickest round-trip

MadridPanama City

MAD - ECP

MADECP

Madrid Barajas

Sun 4/5

1:05 pm-11:04 pm

2 stops16h 59m

Panama City NW Florida Beaches

Sun 4/12

6:43 pm-12:15 pm

1 stop10h 32m

$999

MadridPanama City

MAD - ECP

MADECP

Madrid Barajas

Sun 5/17

10:50 am-10:05 pm

2 stops18h 15m

Panama City NW Florida Beaches

Sat 5/23

9:00 am-8:50 am

3 stops40h 50m

$1,141

MadridPanama City

MAD - ECP

MADECP

Madrid Barajas

Sun 4/5

3:55 pm-12:09 pm

1 stop27h 14m

Panama City NW Florida Beaches

Sun 4/12

12:33 pm-9:05 am

1 stop13h 32m

$1,175

MadridPanama City

MAD - ECP

MADECP

Madrid Barajas

Sat 8/1

3:55 pm-9:34 am

1 stop24h 39m

Panama City NW Florida Beaches

Fri 8/14

5:25 pm-2:25 pm

1 stop14h 00m

$1,181

MadridPanama City

MAD - ECP

MADECP

Madrid Barajas

Mon 4/20

7:35 pm-10:58 am

2 stops22h 23m

Panama City NW Florida Beaches

Fri 4/24

10:48 am-12:50 pm

2 stops19h 02m

$1,318

MadridPanama City

MAD - ECP

MADECP

Madrid Barajas

Sat 8/1

2:35 pm-10:46 pm

2 stops15h 11m

Panama City NW Florida Beaches

Fri 8/14

9:23 am-6:20 am

2 stops13h 57m

$1,405

Flights are sorted by cheapest round-trip flights first.

Deals found on 3/5

Showing 1-10 of 17 resultsSorted by cheapest first
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Best time to book a flight from Spain to Panama City

Have a flexible travel schedule? Discover the best time to fly to Panama City from Spain with our price prediction graph.
Estimated round-trip price
Rates are based on past data. Find the cheapest month and day to book your flight based on your travel requirements, then search for cheap deals.

Cheapflights Insights

Everything you need to know about your flight from Spain to Panama City
No data available for this route at this time. Please check back soon.

Related info for your journey

Find useful and relevant information for your journey from Spain to Panama City. Access travel guides, tips, and recommendations to enhance your travel experience. Get information about local attractions, weather, transportation options, and more.

  • What airport do you fly into for flights to Panama City from Spain?

    Panama City NW Florida Beaches (ECP) is the airport you will fly into if you book a flight from Spain to Panama City. It is only a 16.0 mi journey from NW Florida Beaches (ECP) to Panama City’s city center.

  • How long is the flight from Spain to Panama City, Florida?

    There are many flights that can get you from Spain to Panama City, Florida in 13h 40m. Fly via United Airlines, Virgin Atlantic, or KLM to get the fastest option. The distance between Spain and Panama City, Florida is about 4513 mi. When browsing for deals, the options you’ll see will be for both nonstop flights and flights with stops.

  • Can I find deals for flights from Spain to Panama City that include hotel bookings?

    Yes. In addition to deals on Spain to Panama City flights, Cheapflights offers vacation packages that include both flights and hotel.

  • How can I find direct flights from Spain to Panama City?

    After entering your origin and destination, apply the non-stop filter on the search result page to find direct flights from Spain to Panama City.

  • Can I find deals for business class flights from Spain to Panama City?

    Yes. Cheapflights offers flight deals from Spain to Panama City by cabin class. In addition to browsing deals, you can also filter by cabin class on the search results page after making a search.

See more FAQs

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