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Panama City

$614+ Cheap flights from Spain to Panama City, FL (ECP)

This is the cheapest one-way flight price found by a Cheapflights user in the last 72 hours by searching for a flight departing on 3/2. Fares are subject to change and may not be available on all flights or dates of travel.
MAD — ECP
Feb 21 — Feb 281
Sat 2/21
Sat 2/28
1 adult, Economy
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Cheap flight deals from Spain to Panama City

Cheapest flights from Spain to Panama City
Explore the most affordable flight options available from Spain to Panama City. Find the lowest fares from popular airlines and budget airlines, with prices last updated on January 22, 2026.

This United Airlines deal was found by Cheapflights users on 1/21. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 10/2812:35 pm
MAD
-
ECP
2 stops31h 42m
United Airlines
Sun 11/16:40 am
ECP
-
MAD
2 stops26h 20m
United Airlines
Deal found 1/21$868
This Delta deal was found by Cheapflights users on 1/20. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 1/236:00 am
MAD
-
ECP
2 stops20h 50m
Delta
Tue 1/2712:15 pm
ECP
-
MAD
2 stops22h 25m
Delta
Deal found 1/20$881
This American Airlines deal was found by Cheapflights users on 1/19. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 10/2812:40 pm
MAD
-
ECP
1 stop16h 44m
American Airlines
Sun 11/15:04 pm
ECP
-
MAD
1 stop29h 41m
American Airlines
Deal found 1/19$954
This KLM deal was found by Cheapflights users on 1/22. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure KLM is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 1/2311:00 am
MAD
-
ECP
2 stops18h 38m
Multiple Airlines
Tue 1/2712:15 pm
ECP
-
MAD
2 stops16h 15m
Multiple Airlines
Deal found 1/22$1,156
This American Airlines deal was found by Cheapflights users on 1/20. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 1/231:00 pm
MAD
-
ECP
1 stop32h 54m
American Airlines
Tue 1/277:02 am
ECP
-
MAD
2 stops15h 48m
American Airlines
Deal found 1/20$1,245
This United Airlines deal was found by Cheapflights users on 1/20. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 2/1411:15 am
MAD
-
ECP
2 stops35h 56m
United Airlines
Sat 2/216:30 am
ECP
-
MAD
2 stops19h 45m
United Airlines
Deal found 1/20$4,803

Find flight deals from Spain to Panama City

Keep the following information in mind while searching for Spain to Panama City flight deals. Data was last updated January 22, 2026.

Round-trip from

$4,803
(United Airlines)

One-way from

$614
(Kiwi.com)
From Spain to Panama City NW Florida Beaches
Search Deals
One-way flight from Spain to Panama City NW Florida Beaches
Search Deals

Cheapflights Fare Finder

 
Customize your flight search to find flights from Spain to Panama City that fit within your specific budget. Explore options based on user searches and filter the results based on your desired price range. Find flights that match your budget for a cost-effective journey. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated January 22, 2026.
Use the filters below to find and compare flights from Spain to Panama City that are best for you.

Fly from

Spain

Fly to

Panama City

Route

Depart

Return

Price

MadridPanama City

MAD - ECP

MADECP

Madrid Barajas

Sat 2/14

11:15 am-4:11 pm

2 stops35h 56m

Panama City NW Florida Beaches

Sat 2/21

6:30 am-9:15 am

2 stops19h 45m

$4,803

MadridPanama City

MAD - ECP

MADECP

Madrid Barajas

Sat 2/14

6:00 am-7:30 pm

2 stops20h 30m

Panama City NW Florida Beaches

Sat 2/21

12:10 pm-9:15 am

1 stop14h 05m

$4,827

MadridPanama City

MAD - ECP

MADECP

Madrid Barajas

Sat 2/14

1:00 pm-11:49 pm

1 stop17h 49m

Panama City NW Florida Beaches

Sat 2/21

12:44 pm-9:25 am

1 stop13h 41m

$5,060

MadridPanama City

MAD - ECP

MADECP

Madrid Barajas

Mon 3/2

12:00 pm-11:25 am

3 stops54h 25m

$614

MadridPanama City

MAD - ECP

MADECP

Madrid Barajas

Mon 3/2

12:00 pm-12:44 pm

1 stop31h 44m

$756

MadridPanama City

MAD - ECP

MADECP

Madrid Barajas

Mon 3/2

11:00 am-9:22 pm

2 stops17h 22m

$765

MadridPanama City

MAD - ECP

MADECP

Madrid Barajas

Thu 2/12

10:15 pm-4:15 pm

3 stops49h 00m

$843

MadridPanama City

MAD - ECP

MADECP

Madrid Barajas

Wed 2/11

12:55 am-3:08 pm

1 stop21h 13m

$870

MadridPanama City

MAD - ECP

MADECP

Madrid Barajas

Thu 2/12

1:15 pm-11:49 pm

2 stops17h 34m

$888

Flights are sorted by cheapest round-trip flights first.

Deals found on 1/22

Best time to book a flight from Spain to Panama City

Have a flexible travel schedule? Discover the best time to fly to Panama City from Spain with our price prediction graph.
Estimated round-trip price
Rates are based on past data. Find the cheapest month and day to book your flight based on your travel requirements, then search for cheap deals.

Cheapflights Insights

Everything you need to know about your flight from Spain to Panama City

What is the cheapest month to book a flight from Spain to Panama City, Florida?

Currently, November is the cheapest month in which you can book a flight from Spain to Panama City, Florida (average of $545). Flying from Spain to Panama City, Florida in July is currently the most expensive (average of $1,160). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.

Related info for your journey

Find useful and relevant information for your journey from Spain to Panama City. Access travel guides, tips, and recommendations to enhance your travel experience. Get information about local attractions, weather, transportation options, and more.

  • What airport do you fly into for flights to Panama City from Spain?

    Panama City NW Florida Beaches (ECP) is the airport you will fly into if you book a flight from Spain to Panama City. It is only a 16.0 mi journey from NW Florida Beaches (ECP) to Panama City’s city center.

  • How long is the flight from Spain to Panama City, Florida?

    There are many flights that can get you from Spain to Panama City, Florida in 17h 49m. Fly via United Airlines, Delta, or American Airlines to get the fastest option. The distance between Spain and Panama City, Florida is about 4513 mi. When browsing for deals, the options you’ll see will be for both nonstop flights and flights with stops.

  • Can I find deals for flights from Spain to Panama City that include hotel bookings?

    Yes. In addition to deals on Spain to Panama City flights, Cheapflights offers vacation packages that include both flights and hotel.

  • How can I find direct flights from Spain to Panama City?

    After entering your origin and destination, apply the non-stop filter on the search result page to find direct flights from Spain to Panama City.

  • Can I find deals for business class flights from Spain to Panama City?

    Yes. Cheapflights offers flight deals from Spain to Panama City by cabin class. In addition to browsing deals, you can also filter by cabin class on the search results page after making a search.

  • What is the cheapest month to book a flight from Spain to Panama City, Florida?

    Currently, November is the cheapest month in which you can book a flight from Spain to Panama City, Florida (average of $545). Flying from Spain to Panama City, Florida in July is currently the most expensive (average of $1,160). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.

See more FAQs

Traveling to a place near Panama City?

Book flights to Panama City if you plan to visit one of these locations
Mexico Beach

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