$721+ Cheap flights from Madrid, Spain (MAD) to Panama City, FL (ECP)
This is the cheapest round-trip flight price found by a Cheapflights user in the last 72 hours by searching for a flight departing on 2/26. Fares are subject to change and may not be available on all flights or dates of travel.
MAD — ECP
Mar 14 — Mar 211
1 adult, Economy
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Find cheap flights from Madrid to Panama City with Cheapflights
1. Tell us where you want to go
Enter your travel information like dates, passengers, trip type (one-way or round trip), and preferred cabin class then click “Find deals”2. Select your favorite providers
We find the providers serving your travel needs. Choose up to four travel providers to compare side-by-side for flights, hotels, or car rentals.3. Compare prices and book
Review each provider’s pricing and select the best option for you! Book through your favorite provider’s website for a seamless experience.Cheap flight deals from Madrid to Panama City
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Cheapest flights from Madrid to Panama CityExplore the most affordable flight options available from Madrid to Panama City. Find the lowest fares from popular airlines and budget airlines, with prices last updated on February 12, 2026.
Explore the most affordable flight options available from Madrid to Panama City. Find the lowest fares from popular airlines and budget airlines, with prices last updated on February 12, 2026.
This Delta deal was found by Cheapflights users on 2/10. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 2/266:00 am
MAD
- ECP
2 stops23h 39m
Delta
Mon 3/29:26 am
ECP
- MAD
2 stops19h 04m
Delta
Deal found 2/10![Delta logo]()
$721
This KLM deal was found by Cheapflights users on 2/11. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure KLM is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 2/2611:15 am
MAD
- ECP
1 stop35h 02m
Multiple Airlines
Mon 3/22:05 pm
ECP
- MAD
2 stops14h 25m
Multiple Airlines
Deal found 2/11![Multiple Airlines logo]()
$726
This KLM deal was found by Cheapflights users on 2/10. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure KLM is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 2/2611:15 am
MAD
- ECP
1 stop15h 15m
KLM
Mon 3/22:05 pm
ECP
- MAD
1 stop12h 10m
KLM
Deal found 2/10![KLM logo]()
$729
This Virgin Atlantic deal was found by Cheapflights users on 2/11. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Virgin Atlantic is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 2/2611:15 am
MAD
- ECP
1 stop13h 04m
Virgin Atlantic
Mon 3/24:04 pm
ECP
- MAD
1 stop10h 11m
Virgin Atlantic
Deal found 2/11![Virgin Atlantic logo]()
$730
This United Airlines deal was found by Cheapflights users on 2/9. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 10/2812:35 pm
MAD
- ECP
2 stops31h 42m
United Airlines
Sun 11/14:55 pm
ECP
- MAD
2 stops37h 05m
United Airlines
Deal found 2/9![United Airlines logo]()
$881
This American Airlines deal was found by Cheapflights users on 2/9. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 10/2812:40 pm
MAD
- ECP
1 stop16h 44m
American Airlines
Sun 11/11:19 pm
ECP
- MAD
2 stops33h 26m
American Airlines
Deal found 2/9![American Airlines logo]()
$974
Best flights from Madrid to Panama CityDiscover carefully curated flight deals from Madrid to Panama City that have cost, travel time, and layovers in mind to ensure you get the best travel experience. Data last updated February 12, 2026.
Discover carefully curated flight deals from Madrid to Panama City that have cost, travel time, and layovers in mind to ensure you get the best travel experience. Data last updated February 12, 2026.
This Delta deal was found by Cheapflights users on 2/10. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 2/266:00 am
MAD
- ECP
2 stops23h 39m
Delta
Mon 3/29:26 am
ECP
- MAD
2 stops19h 04m
Delta
Deal found 2/10![Delta logo]()
$721
This KLM deal was found by Cheapflights users on 2/11. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure KLM is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 2/2611:15 am
MAD
- ECP
1 stop35h 02m
Multiple Airlines
Mon 3/22:05 pm
ECP
- MAD
2 stops14h 25m
Multiple Airlines
Deal found 2/11![Multiple Airlines logo]()
$726
This KLM deal was found by Cheapflights users on 2/10. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure KLM is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 2/2611:15 am
MAD
- ECP
1 stop15h 15m
KLM
Mon 3/22:05 pm
ECP
- MAD
1 stop12h 10m
KLM
Deal found 2/10![KLM logo]()
$729
This Virgin Atlantic deal was found by Cheapflights users on 2/11. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Virgin Atlantic is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 2/2611:15 am
MAD
- ECP
1 stop13h 04m
Virgin Atlantic
Mon 3/24:04 pm
ECP
- MAD
1 stop10h 11m
Virgin Atlantic
Deal found 2/11![Virgin Atlantic logo]()
$730
This American Airlines deal was found by Cheapflights users on 2/9. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 6/243:55 pm
MAD
- ECP
1 stop24h 41m
American Airlines
Mon 9/71:10 pm
ECP
- MAD
1 stop11h 45m
American Airlines
Deal found 2/9![American Airlines logo]()
$987
This Delta deal was found by Cheapflights users on 2/9. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 6/241:05 pm
MAD
- ECP
2 stops26h 12m
Delta
Mon 9/77:05 pm
ECP
- MAD
2 stops17h 30m
Delta
Deal found 2/9![Delta logo]()
$983
Last-minute flights from Madrid to Panama CityDiscover last-minute flight deals from Madrid to Panama City. Data last updated February 12, 2026 and is based on user searches.
Discover last-minute flight deals from Madrid to Panama City. Data last updated February 12, 2026 and is based on user searches.
This Delta deal was found by Cheapflights users on 2/10. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 2/266:00 am
MAD
- ECP
2 stops23h 39m
Delta
Mon 3/29:26 am
ECP
- MAD
2 stops19h 04m
Delta
Deal found 2/10![Delta logo]()
$721
This KLM deal was found by Cheapflights users on 2/11. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure KLM is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 2/2611:15 am
MAD
- ECP
1 stop35h 02m
Multiple Airlines
Mon 3/22:05 pm
ECP
- MAD
2 stops14h 25m
Multiple Airlines
Deal found 2/11![Multiple Airlines logo]()
$726
This KLM deal was found by Cheapflights users on 2/10. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure KLM is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 2/2611:15 am
MAD
- ECP
1 stop15h 15m
KLM
Mon 3/22:05 pm
ECP
- MAD
1 stop12h 10m
KLM
Deal found 2/10![KLM logo]()
$729
This Virgin Atlantic deal was found by Cheapflights users on 2/11. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Virgin Atlantic is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 2/2611:15 am
MAD
- ECP
1 stop13h 04m
Virgin Atlantic
Mon 3/24:04 pm
ECP
- MAD
1 stop10h 11m
Virgin Atlantic
Deal found 2/11![Virgin Atlantic logo]()
$730
One-way flights from Madrid to Panama CitySearch for one-way flight options from Madrid to Panama City. Find affordable one-way fares based on user searches. Data last updated February 12, 2026.
Search for one-way flight options from Madrid to Panama City. Find affordable one-way fares based on user searches. Data last updated February 12, 2026.
This Kiwi.com deal was found by Cheapflights users on 2/12. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 3/238:50 pm
MAD
- ECP
3 stops32h 14m
Multiple Airlines
Deal found 2/12![Multiple Airlines logo]()
$776
This Kiwi.com deal was found by Cheapflights users on 2/12. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 3/246:30 am
MAD
- ECP
3 stops22h 34m
Multiple Airlines
Deal found 2/12![Multiple Airlines logo]()
$795
This Kiwi.com deal was found by Cheapflights users on 2/12. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 3/215:30 pm
MAD
- ECP
3 stops54h 28m
Multiple Airlines
Deal found 2/12![Multiple Airlines logo]()
$797
This American Airlines deal was found by Cheapflights users on 2/12. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 3/2412:30 pm
MAD
- ECP
1 stop15h 47m
American Airlines
Deal found 2/12![American Airlines logo]()
$815
This Kiwi.com deal was found by Cheapflights users on 2/9. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 3/56:35 am
MAD
- ECP
3 stops35h 50m
Multiple Airlines
Deal found 2/9![Multiple Airlines logo]()
$827
This Kiwi.com deal was found by Cheapflights users on 2/12. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 3/257:05 pm
MAD
- ECP
3 stops47h 40m
Multiple Airlines
Deal found 2/12![Multiple Airlines logo]()
$840
This Kiwi.com deal was found by Cheapflights users on 2/12. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 3/224:55 pm
MAD
- ECP
3 stops36h 09m
Multiple Airlines
Deal found 2/12![Multiple Airlines logo]()
$857
This American Airlines deal was found by Cheapflights users on 2/9. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 3/511:00 am
MAD
- ECP
2 stops17h 22m
American Airlines
Deal found 2/9![American Airlines logo]()
$895
This American Airlines deal was found by Cheapflights users on 2/11. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 2/1812:40 pm
MAD
- ECP
1 stop15h 42m
American Airlines
Deal found 2/11![American Airlines logo]()
$896
Find flight deals from Madrid to Panama City
Discover tips and strategies to find the most affordable flight options for your journey from Madrid (MAD) to Panama City (ECP). Learn about various techniques such as flexible date searches, comparing prices across and setting up price alerts. Use these methods to find the cheapest flights available for your travel needs. Data last updated February 12, 2026.
Most accurate provider | FlightHub 3 stars |
|---|---|
Most trusted provider | FlightHub 3 stars |
Round-trip from | $721 (Delta) |
Cheapflights Fare Finder
Customize your flight search to find flights from Madrid to Panama City that fit within your specific budget. Explore options based on user searches and filter the results based on your desired price range. Find flights that match your budget for a cost-effective journey. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated February 12, 2026.
Use the filters below to find and compare flights from Madrid to Panama City that are best for you.
Fly from
Madrid
Fly to
Panama City
Route
Depart
Return
Price
MadridPanama City
MAD - ECP
MADECP
Madrid Barajas
Thu 2/26
6:00 am-10:39 pm
2 stops23h 39m
Panama City NW Florida Beaches
Mon 3/2
9:26 am-11:30 am
2 stops19h 04m
$721
MadridPanama City
MAD - ECP
MADECP
Madrid Barajas
Thu 2/26
11:15 am-3:17 pm
1 stop35h 02m
Panama City NW Florida Beaches
Mon 3/2
2:05 pm-11:30 am
2 stops14h 25m
$726
MadridPanama City
MAD - ECP
MADECP
Madrid Barajas
Thu 2/26
11:15 am-7:30 pm
1 stop15h 15m
Panama City NW Florida Beaches
Mon 3/2
2:05 pm-9:15 am
1 stop12h 10m
$729
MadridPanama City
MAD - ECP
MADECP
Madrid Barajas
Thu 2/26
11:15 am-5:19 pm
1 stop13h 04m
Panama City NW Florida Beaches
Mon 3/2
4:04 pm-9:15 am
1 stop10h 11m
$730
MadridPanama City
MAD - ECP
MADECP
Madrid Barajas
Wed 6/24
1:05 pm-8:17 am
2 stops26h 12m
Panama City NW Florida Beaches
Mon 9/7
7:05 pm-7:35 pm
2 stops17h 30m
$983
MadridPanama City
MAD - ECP
MADECP
Madrid Barajas
Wed 6/24
3:55 pm-9:36 am
1 stop24h 41m
Panama City NW Florida Beaches
Mon 9/7
1:10 pm-7:55 am
1 stop11h 45m
$987
MadridPanama City
MAD - ECP
MADECP
Madrid Barajas
Mon 3/23
8:50 pm-11:04 pm
3 stops32h 14m
$776
MadridPanama City
MAD - ECP
MADECP
Madrid Barajas
Tue 3/24
6:30 am-11:04 pm
3 stops22h 34m
$795
MadridPanama City
MAD - ECP
MADECP
Madrid Barajas
Sat 3/21
5:30 pm-5:58 pm
3 stops54h 28m
$797
MadridPanama City
MAD - ECP
MADECP
Madrid Barajas
Tue 3/24
12:30 pm-10:17 pm
1 stop15h 47m
$815
Showing 1-10 of 15 results
Compare providers for flights from Madrid to Panama City
Provider information is updated monthly. Please note that these providers often have deals for this flight, but the availability may vary on a day-by-day basis on Cheapflights.
Use the table below to compare price accuracy, trust ratings, and cancellation policies for each provider offering flight deals from Madrid to Panama City in February.
| Provider | Price Accuracy | Trust Score* |
|---|---|---|
| Price Accuracy3 stars | Trust Score*3 stars | |
| Price Accuracy2 stars | Trust Score*2 stars |
- Most accurate provider: When it comes to deals on Madrid-Panama City, Florida flights, users find the pricing of FlightHub to be most consistent on Cheapflights vs. FlightHub Users can find the same prices on Madrid-Panama City, Florida flight deals on Cheapflights vs. FlightHub >95% of the time. Price accuracy is based on data collected from Madrid-Panama City, Florida flight searches over the past month and is updated monthly.
- Most trusted provider: When it comes to deals on Madrid-Panama City, Florida flights, Cheapflights users trust FlightHub the most. FlightHub has received a user feedback score of 3 out of 3 stars (3 being the best), meaning they have been trusted the most by Cheapflights users looking for Madrid-Panama City, Florida flight deals. Provider user feedback score is based on Cheapflights searches over the past month and is updated monthly.
Best time to book a flight from Madrid to Panama City
Have a flexible travel schedule? Discover the best time to fly to Panama City from Madrid with our price prediction graph.
MAD-ECP
Estimated round-trip price
Rates are based on past data. Find the cheapest month and day to book your flight based on your travel requirements, then search for cheap deals.
Related info for your journey
Find useful and relevant information for your journey from Madrid to Panama City. Access travel guides, tips, and recommendations to enhance your travel experience. Get information about local attractions, weather, transportation options, and more.
Traveling to a place near Panama City?
Book flights to Panama City if you plan to visit one of these locationsMexico Beach
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