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Panama City

$615+ Cheap flights from Madrid, Spain (MAD) to Panama City, FL (ECP)

This is the cheapest round-trip flight price found by a Cheapflights user in the last 72 hours by searching for a flight departing on 11/12. Fares are subject to change and may not be available on all flights or dates of travel.
MAD — ECP
oct. 17 — oct. 241
vie. 10/17
vie. 10/24
1 adult, Economy
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Cheap flight deals from Madrid to Panama City

Discover tips and strategies to find the most affordable flight options for your journey from Madrid (MAD) to Panama City (ECP). Learn about various techniques such as flexible date searches, comparing prices across and setting up price alerts. Use these methods to find the cheapest flights available for your travel needs. Data last updated septiembre 17, 2025.

Round-trip from

$615
(American Airlines)
From Madrid Barajas to Panama City NW Florida Beaches
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Find flight deals from Madrid to Panama City

Cheapest flights from Madrid to Panama City
Explore the most affordable flight options available from Madrid to Panama City. Find the lowest fares from popular airlines and budget airlines, with prices last updated on septiembre 17, 2025.

This American Airlines deal was found by Cheapflights users on 9/16. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
mié. 11/121:00 pmMAD - ECP
1 stop32h 07mAmerican Airlines
mié. 1/143:38 pmECP - MAD
1 stop34h 47mAmerican Airlines
Deal found 9/16$615
This American Airlines deal was found by Cheapflights users on 9/17. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
mié. 11/1212:55 amMAD - ECP
1 stop18h 33mAmerican Airlines
mié. 1/146:48 amECP - MAD
1 stop19h 37mAmerican Airlines
Deal found 9/17$624
This American Airlines deal was found by Cheapflights users on 9/15. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
mar. 9/2312:40 pmMAD - ECP
1 stop15h 32mAmerican Airlines
lun. 9/293:53 pmECP - MAD
1 stop15h 32mAmerican Airlines
Deal found 9/15$651
This American Airlines deal was found by Cheapflights users on 9/16. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
jue. 10/24:00 pmMAD - ECP
1 stop26h 07mAmerican Airlines
lun. 10/61:47 pmECP - MAD
2 stops13h 43mAmerican Airlines
Deal found 9/16$658
This American Airlines deal was found by Cheapflights users on 9/15. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
jue. 10/301:00 pmMAD - ECP
1 stop28h 28mAmerican Airlines
jue. 11/611:04 amECP - MAD
1 stop11h 41mAmerican Airlines
Deal found 9/15$729

Cheapflights Fare Finder

 
Customize your flight search to find flights from Madrid to Panama City that fit within your specific budget. Explore options based on user searches and filter the results based on your desired price range. Find flights that match your budget for a cost-effective journey. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated septiembre 17, 2025.
Use the filters below to find and compare flights from Madrid to Panama City that are best for you.

Fly from

Madrid

Fly to

Panama City

Route

Depart

Return

Price

MadridPanama City

MAD - ECP

MADECP

Madrid Barajas

mié. 11/12

12:40 pm-2:52 pm

1 stop33h 12m

Panama City NW Florida Beaches

mié. 1/14

11:12 am-8:55 am

2 stops14h 43m

$615

MadridPanama City

MAD - ECP

MADECP

Madrid Barajas

mié. 11/12

12:55 am-12:28 pm

1 stop18h 33m

Panama City NW Florida Beaches

mié. 1/14

6:48 am-9:25 am

1 stop19h 37m

$624

MadridPanama City

MAD - ECP

MADECP

Madrid Barajas

vie. 1/16

12:55 am-2:19 pm

1 stop20h 24m

Panama City NW Florida Beaches

sáb. 2/7

6:48 am-9:25 am

1 stop19h 37m

$630

MadridPanama City

MAD - ECP

MADECP

Madrid Barajas

vie. 10/17

12:40 pm-9:34 pm

1 stop15h 54m

$830

MadridPanama City

MAD - ECP

MADECP

Madrid Barajas

vie. 10/17

12:40 pm-9:34 pm

1 stop15h 54m

$3,191

Flights are sorted by cheapest round-trip flights first.

Deals found on 9/15

Best time to book a flight from Madrid to Panama City

Have a flexible travel schedule? Discover the best time to fly to Panama City from Madrid with our price prediction graph.
Estimated round-trip price
Rates are based on past data. Find the cheapest month and day to book your flight based on your travel requirements, then search for cheap deals.

Cheapflights Insights

Everything you need to know about your flight from Madrid to Panama City

What is the cheapest month to book a flight from Madrid to Panama City, Florida?

Currently, January is the cheapest month in which you can book a flight from Madrid to Panama City, Florida (average of $346). Flying from Madrid to Panama City, Florida in March is currently the most expensive (average of $459). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.

Related info for your journey

Find useful and relevant information for your journey from Madrid to Panama City. Access travel guides, tips, and recommendations to enhance your travel experience. Get information about local attractions, weather, transportation options, and more.

  • How long is the flight from Madrid to Panama City, Florida?

    A quick flight from Madrid to Panama City, Florida can take about 33h 12m. American Airlines provides one of the quickest options available for as low as $615. The distance between Madrid and Panama City, Florida is about 4513 mi.

  • Can I find deals for flights from Madrid to Panama City that include hotel bookings?

    Yes. In addition to deals on Madrid to Panama City flights, Cheapflights offers vacation packages that include both flights and hotel.

  • How can I find direct flights from Madrid to Panama City?

    After entering your origin and destination, apply the non-stop filter on the search result page to find direct flights from Madrid to Panama City.

  • Can I find deals for business class flights from Madrid to Panama City?

    Yes. Cheapflights offers flight deals from Madrid to Panama City by cabin class. In addition to browsing deals, you can also filter by cabin class on the search results page after making a search.

  • What is the cheapest month to book a flight from Madrid to Panama City, Florida?

    Currently, January is the cheapest month in which you can book a flight from Madrid to Panama City, Florida (average of $346). Flying from Madrid to Panama City, Florida in March is currently the most expensive (average of $459). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.

See more FAQs

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