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Panama City

$458+ Cheap flights from Madrid, Spain (MAD) to Panama City, FL (ECP)

This is the cheapest one-way flight price found by a Cheapflights user in the last 72 hours by searching for a flight departing on 2/16. Fares are subject to change and may not be available on all flights or dates of travel.
MAD — ECP
Nov 26 — Dec 31
Wed 11/26
Wed 12/3
1 adult, Economy
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Find flight deals from Madrid to Panama City

Cheapest flights from Madrid to Panama City
Explore the most affordable flight options available from Madrid to Panama City. Find the lowest fares from popular airlines and budget airlines, with prices last updated on October 27, 2025.

This American Airlines deal was found by Cheapflights users on 10/26. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 12/171:15 pmMAD - ECP
2 stops16h 55mAmerican Airlines
Fri 1/27:15 amECP - MAD
1 stop15h 30mAmerican Airlines
Deal found 10/26$976
This American Airlines deal was found by Cheapflights users on 10/25. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 12/512:55 amMAD - ECP
1 stop25h 16mAmerican Airlines
Sun 1/47:15 amECP - MAD
1 stop15h 30mAmerican Airlines
Deal found 10/25$1,011
This Delta deal was found by Cheapflights users on 10/27. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 10/281:05 pmMAD - ECP
2 stops27h 14mDelta
Wed 11/121:32 pmECP - MAD
2 stops21h 08mDelta
Deal found 10/27$1,219
This United Airlines deal was found by Cheapflights users on 10/26. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 12/175:55 amMAD - ECP
3 stops22h 54mUnited Airlines
Fri 1/26:15 amECP - MAD
2 stops20h 00mUnited Airlines
Deal found 10/26$1,282
This American Airlines deal was found by Cheapflights users on 10/27. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 10/2810:25 amMAD - ECP
2 stops18h 28mAmerican Airlines
Wed 11/128:21 amECP - MAD
1 stop14h 24mAmerican Airlines
Deal found 10/27$1,326
This United Airlines deal was found by Cheapflights users on 10/27. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 10/286:00 amMAD - ECP
3 stops21h 49mUnited Airlines
Wed 11/126:30 amECP - MAD
2 stops23h 45mUnited Airlines
Deal found 10/27$1,590
This Air France deal was found by Cheapflights users on 10/27. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Air France is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 10/2810:05 amMAD - ECP
1 stop19h 05mMultiple Airlines
Wed 11/125:00 pmECP - MAD
1 stop33h 15mMultiple Airlines
Deal found 10/27$1,967

Cheap flight deals from Madrid to Panama City

Discover tips and strategies to find the most affordable flight options for your journey from Madrid (MAD) to Panama City (ECP). Learn about various techniques such as flexible date searches, comparing prices across and setting up price alerts. Use these methods to find the cheapest flights available for your travel needs. Data last updated October 27, 2025.

Most accurate provider

eDreams
3 stars

Most trusted provider

eDreams
3 stars

Round-trip from

$718
(United Airlines)

One-way from

$458
(American Airlines)
Provider with most accurate pricing for Madrid Barajas-Panama City NW Florida Beaches flight deals.
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Provider most trusted by Cheapflights users for Madrid Barajas-Panama City NW Florida Beaches flights.
Search Deals
From Madrid Barajas to Panama City NW Florida Beaches
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One-way flight from Madrid Barajas to Panama City NW Florida Beaches
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Cheapflights Fare Finder

 
Customize your flight search to find flights from Madrid to Panama City that fit within your specific budget. Explore options based on user searches and filter the results based on your desired price range. Find flights that match your budget for a cost-effective journey. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated October 27, 2025.
Use the filters below to find and compare flights from Madrid to Panama City that are best for you.

Fly from

Madrid

Fly to

Panama City

Route

Depart

Return

Price

MadridPanama City

MAD - ECP

MADECP

Madrid Barajas

Fri 2/20

8:35 am-9:56 pm

2 stops20h 21m

Panama City NW Florida Beaches

Tue 2/24

6:30 am-9:15 am

2 stops19h 45m

$718

MadridPanama City

MAD - ECP

MADECP

Madrid Barajas

Fri 2/20

6:00 am-3:17 pm

2 stops16h 17m

Panama City NW Florida Beaches

Tue 2/24

9:23 am-9:15 am

1 stop16h 52m

$780

MadridPanama City

MAD - ECP

MADECP

Madrid Barajas

Fri 2/20

1:00 pm-8:17 pm

1 stop14h 17m

Panama City NW Florida Beaches

Tue 2/24

12:40 pm-9:25 am

1 stop13h 45m

$911

MadridPanama City

MAD - ECP

MADECP

Madrid Barajas

Wed 12/17

1:15 pm-11:10 pm

2 stops16h 55m

Panama City NW Florida Beaches

Fri 1/2

7:15 am-5:45 am

2 stops15h 30m

$976

MadridPanama City

MAD - ECP

MADECP

Madrid Barajas

Fri 12/5

12:55 am-7:11 pm

1 stop25h 16m

Panama City NW Florida Beaches

Sun 1/4

7:15 am-5:45 am

1 stop15h 30m

$1,011

MadridPanama City

MAD - ECP

MADECP

Madrid Barajas

Mon 2/16

1:00 pm-11:50 pm

1 stop17h 50m

$458

MadridPanama City

MAD - ECP

MADECP

Madrid Barajas

Wed 2/18

1:00 pm-9:54 pm

1 stop15h 54m

$458

MadridPanama City

MAD - ECP

MADECP

Madrid Barajas

Wed 2/18

11:00 pm-10:42 pm

3 stops30h 42m

$739

MadridPanama City

MAD - ECP

MADECP

Madrid Barajas

Mon 2/16

7:25 am-9:56 pm

3 stops21h 31m

$1,578

MadridPanama City

MAD - ECP

MADECP

Madrid Barajas

Wed 11/12

5:00 pm-11:07 pm

2 stops37h 07m

$3,302

Flights are sorted by cheapest round-trip flights first.

Deals found on 10/26

Showing 1-10 of 14 results
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Compare providers for flights from Madrid to Panama City

Provider information is updated monthly. Please note that these providers often have deals for this flight, but the availability may vary on a day-by-day basis on Cheapflights.
Use the table below to compare price accuracy, trust ratings, and cancellation policies for each provider offering flight deals from Madrid to Panama City in October.
ProviderPrice AccuracyTrust Score*
eDreamsPrice Accuracy3 starsTrust Score*3 stars
FlightHubPrice Accuracy3 starsTrust Score*1 star
AranGrantPrice Accuracy2 starsTrust Score*3 stars

*The Trust Score is based on feedback from users after their booking experience. It measures overall satisfaction, helping us identify issues like hidden fees, problems during the ticketing process, and the quality of customer service. This score is our best indicator of the provider's quality and reliability.

  • Most accurate provider: When it comes to deals on Madrid-Panama City, Florida flights, users find the pricing of eDreams to be most consistent on Cheapflights vs. eDreams Users can find the same prices on Madrid-Panama City, Florida flight deals on Cheapflights vs. eDreams >95% of the time. Price accuracy is based on data collected from Madrid-Panama City, Florida flight searches over the past month and is updated monthly.
  • Most trusted provider: When it comes to deals on Madrid-Panama City, Florida flights, Cheapflights users trust eDreams the most. eDreams has received a user feedback score of 3 out of 3 stars (3 being the best), meaning they have been trusted the most by Cheapflights users looking for Madrid-Panama City, Florida flight deals. Provider user feedback score is based on Cheapflights searches over the past month and is updated monthly.

Best time to book a flight from Madrid to Panama City

Have a flexible travel schedule? Discover the best time to fly to Panama City from Madrid with our price prediction graph.
Estimated round-trip price
Rates are based on past data. Find the cheapest month and day to book your flight based on your travel requirements, then search for cheap deals.

Cheapflights Insights

Everything you need to know about your flight from Madrid to Panama City

What is the cheapest month to book a flight from Madrid to Panama City, Florida?

Currently, November is the cheapest month in which you can book a flight from Madrid to Panama City, Florida (average of $533). Flying from Madrid to Panama City, Florida in July is currently the most expensive (average of $1,160). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.

Related info for your journey

Find useful and relevant information for your journey from Madrid to Panama City. Access travel guides, tips, and recommendations to enhance your travel experience. Get information about local attractions, weather, transportation options, and more.

  • How long is the flight from Madrid to Panama City, Florida?

    A quick flight from Madrid to Panama City, Florida can take about 16h 17m. United Airlines provides one of the quickest options available for as low as $780. The distance between Madrid and Panama City, Florida is about 4513 mi. Both multi-stop and nonstop flights can be found to your destination and back.

  • Can I find deals for flights from Madrid to Panama City that include hotel bookings?

    Yes. In addition to deals on Madrid to Panama City flights, Cheapflights offers vacation packages that include both flights and hotel.

  • How can I find direct flights from Madrid to Panama City?

    After entering your origin and destination, apply the non-stop filter on the search result page to find direct flights from Madrid to Panama City.

  • Can I find deals for business class flights from Madrid to Panama City?

    Yes. Cheapflights offers flight deals from Madrid to Panama City by cabin class. In addition to browsing deals, you can also filter by cabin class on the search results page after making a search.

  • What is the cheapest month to book a flight from Madrid to Panama City, Florida?

    Currently, November is the cheapest month in which you can book a flight from Madrid to Panama City, Florida (average of $533). Flying from Madrid to Panama City, Florida in July is currently the most expensive (average of $1,160). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.

See more FAQs

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