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Panama City

$649+ Cheap flights from Lisbon (LIS) to Panama City, FL (ECP)

This is the cheapest round-trip flight price found by a Cheapflights user in the last 72 hours by searching for a flight departing on 2/11. Fares are subject to change and may not be available on all flights or dates of travel.
LIS — ECP
Feb 26 — Mar 51
Thu 2/26
Thu 3/5
1 adult, Economy
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Cheap flight deals from Lisbon to Panama City

Cheapest flights from Lisbon to Panama City
Explore the most affordable flight options available from Lisbon to Panama City. Find the lowest fares from popular airlines and budget airlines, with prices last updated on January 27, 2026.

This American Airlines deal was found by Cheapflights users on 1/25. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 2/116:30 am
LIS
-
ECP
2 stops20h 49m
American Airlines
Sun 2/154:34 pm
ECP
-
LIS
2 stops19h 11m
American Airlines
Deal found 1/25$649
This American Airlines deal was found by Cheapflights users on 1/26. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 9/156:35 am
LIS
-
ECP
2 stops33h 40m
American Airlines
Thu 9/2411:14 am
ECP
-
LIS
2 stops29h 46m
American Airlines
Deal found 1/26$651
This American Airlines deal was found by Cheapflights users on 1/26. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 9/156:35 am
LIS
-
ECP
2 stops19h 57m
American Airlines
Fri 9/253:53 pm
ECP
-
LIS
2 stops25h 17m
American Airlines
Deal found 1/26$656
This American Airlines deal was found by Cheapflights users on 1/26. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 9/206:35 am
LIS
-
ECP
2 stops33h 40m
American Airlines
Mon 9/287:00 pm
ECP
-
LIS
2 stops40h 55m
American Airlines
Deal found 1/26$663
This American Airlines deal was found by Cheapflights users on 1/26. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 9/206:35 am
LIS
-
ECP
2 stops33h 40m
American Airlines
Fri 9/253:53 pm
ECP
-
LIS
2 stops59h 12m
American Airlines
Deal found 1/26$685
This American Airlines deal was found by Cheapflights users on 1/26. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 9/156:35 am
LIS
-
ECP
2 stops37h 37m
American Airlines
Sun 9/273:29 pm
ECP
-
LIS
2 stops42h 36m
American Airlines
Deal found 1/26$706
This American Airlines deal was found by Cheapflights users on 1/26. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 9/151:40 pm
LIS
-
ECP
2 stops35h 10m
American Airlines
Sat 9/267:00 pm
ECP
-
LIS
2 stops17h 05m
American Airlines
Deal found 1/26$711
This American Airlines deal was found by Cheapflights users on 1/26. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 9/198:25 am
LIS
-
ECP
2 stops16h 25m
American Airlines
Sat 9/262:36 pm
ECP
-
LIS
2 stops15h 14m
American Airlines
Deal found 1/26$722
This American Airlines deal was found by Cheapflights users on 1/26. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 9/207:20 am
LIS
-
ECP
2 stops41h 30m
American Airlines
Sat 9/267:00 pm
ECP
-
LIS
2 stops46h 00m
American Airlines
Deal found 1/26$723
This Delta deal was found by Cheapflights users on 1/26. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 9/215:35 am
LIS
-
ECP
2 stops20h 02m
Delta
Thu 9/244:10 pm
ECP
-
LIS
2 stops19h 40m
Delta
Deal found 1/26$983
This United Airlines deal was found by Cheapflights users on 1/26. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 9/2012:55 pm
LIS
-
ECP
2 stops30h 14m
United Airlines
Thu 9/242:15 pm
ECP
-
LIS
2 stops14h 50m
United Airlines
Deal found 1/26$1,163

Find flight deals from Lisbon to Panama City

Discover tips and strategies to find the most affordable flight options for your journey from Lisbon (LIS) to Panama City (ECP). Learn about various techniques such as flexible date searches, comparing prices across and setting up price alerts. Use these methods to find the cheapest flights available for your travel needs. Data last updated January 27, 2026.

Round-trip from

$648
(American Airlines)
From Lisbon Humberto Delgado to Panama City NW Florida Beaches
Search Deals

Cheapflights Fare Finder

 
Customize your flight search to find flights from Lisbon to Panama City that fit within your specific budget. Explore options based on user searches and filter the results based on your desired price range. Find flights that match your budget for a cost-effective journey. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated January 27, 2026.
Use the filters below to find and compare flights from Lisbon to Panama City that are best for you.

Fly from

Lisbon

Fly to

Panama City

Route

Depart

Return

Price

LisbonPanama City

LIS - ECP

LISECP

Lisbon Humberto Delgado

Wed 2/11

6:30 am-9:19 pm

2 stops20h 49m

Panama City NW Florida Beaches

Sun 2/15

4:34 pm-5:45 pm

2 stops19h 11m

$649

LisbonPanama City

LIS - ECP

LISECP

Lisbon Humberto Delgado

Sat 6/27

7:10 am-10:34 pm

2 stops21h 24m

$993

LisbonPanama City

LIS - ECP

LISECP

Lisbon Humberto Delgado

Sat 6/27

7:10 am-6:23 pm

2 stops17h 13m

$1,059

Flights are sorted by cheapest round-trip flights first.

Deals found on 1/27

Best time to book a flight from Lisbon to Panama City

Have a flexible travel schedule? Discover the best time to fly to Panama City from Lisbon with our price prediction graph.
Estimated round-trip price
Rates are based on past data. Find the cheapest month and day to book your flight based on your travel requirements, then search for cheap deals.

Related info for your journey

Find useful and relevant information for your journey from Lisbon to Panama City. Access travel guides, tips, and recommendations to enhance your travel experience. Get information about local attractions, weather, transportation options, and more.

  • How long is the flight from Lisbon to Panama City, Florida?

    A quick flight from Lisbon to Panama City, Florida can take about 20h 49m. American Airlines provides one of the quickest options available for as low as $649. There are 4271 mi between Lisbon and Panama City, Florida.

  • Can I find deals for flights from Lisbon to Panama City that include hotel bookings?

    Yes. In addition to deals on Lisbon to Panama City flights, Cheapflights offers vacation packages that include both flights and hotel.

  • How can I find direct flights from Lisbon to Panama City?

    After entering your origin and destination, apply the non-stop filter on the search result page to find direct flights from Lisbon to Panama City.

  • Can I find deals for business class flights from Lisbon to Panama City?

    Yes. Cheapflights offers flight deals from Lisbon to Panama City by cabin class. In addition to browsing deals, you can also filter by cabin class on the search results page after making a search.

See more FAQs

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