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Panama City

$641+ Cheap flights from Frankfurt (FRA) to Panama City, FL (ECP)

This is the cheapest round-trip flight price found by a Cheapflights user in the last 72 hours by searching for a flight departing on 2/23. Fares are subject to change and may not be available on all flights or dates of travel.
FRA — ECP
Feb 25 — Mar 41
Wed 2/25
Wed 3/4
1 adult, Economy
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Cheap flight deals from Frankfurt to Panama City

Cheapest flights from Frankfurt to Panama City
Explore the most affordable flight options available from Frankfurt to Panama City. Find the lowest fares from popular airlines and budget airlines, with prices last updated on January 26, 2026.

This American Airlines deal was found by Cheapflights users on 1/26. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 10/79:20 am
FRA
-
ECP
2 stops31h 50m
American Airlines
Fri 10/233:49 pm
ECP
-
FRA
2 stops19h 26m
American Airlines
Deal found 1/26$641
This American Airlines deal was found by Cheapflights users on 1/26. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 9/159:20 am
FRA
-
ECP
1 stop16h 30m
American Airlines
Wed 9/232:36 pm
ECP
-
FRA
2 stops16h 14m
American Airlines
Deal found 1/26$644
This Flighttix deal was found by Cheapflights users on 1/26. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Flighttix is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 2/210:15 am
FRA
-
ECP
2 stops33h 49m
British Airways
Sat 2/73:27 pm
ECP
-
FRA
2 stops32h 48m
British Airways
Deal found 1/26$646
This American Airlines deal was found by Cheapflights users on 1/26. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 10/812:10 pm
FRA
-
ECP
2 stops37h 25m
American Airlines
Thu 10/227:32 pm
ECP
-
FRA
2 stops39h 43m
American Airlines
Deal found 1/26$647
This American Airlines deal was found by Cheapflights users on 1/26. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 9/159:20 am
FRA
-
ECP
2 stops31h 55m
American Airlines
Sat 9/263:53 pm
ECP
-
FRA
2 stops19h 57m
American Airlines
Deal found 1/26$648
This American Airlines deal was found by Cheapflights users on 1/26. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 10/46:40 am
FRA
-
ECP
2 stops20h 52m
American Airlines
Fri 10/2311:46 am
ECP
-
FRA
2 stops23h 29m
American Airlines
Deal found 1/26$649
This American Airlines deal was found by Cheapflights users on 1/26. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 9/186:10 am
FRA
-
ECP
2 stops21h 22m
American Airlines
Wed 9/237:00 pm
ECP
-
FRA
2 stops16h 15m
American Airlines
Deal found 1/26$652
This American Airlines deal was found by Cheapflights users on 1/26. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 9/179:20 am
FRA
-
ECP
1 stop31h 25m
American Airlines
Mon 9/287:00 pm
ECP
-
FRA
2 stops17h 45m
American Airlines
Deal found 1/26$655
This Delta deal was found by Cheapflights users on 1/25. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 2/111:50 am
FRA
-
ECP
2 stops17h 50m
Delta
Sat 2/286:00 am
ECP
-
FRA
2 stops18h 50m
Delta
Deal found 1/25$656
This Expedia deal was found by Cheapflights users on 1/26. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Expedia is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 2/211:50 am
FRA
-
ECP
2 stops17h 50m
KLM
Sat 2/74:45 pm
ECP
-
FRA
2 stops35h 20m
KLM
Deal found 1/26$658
This American Airlines deal was found by Cheapflights users on 1/26. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 10/46:40 am
FRA
-
ECP
2 stops20h 52m
American Airlines
Sat 10/243:49 pm
ECP
-
FRA
1 stop33h 26m
American Airlines
Deal found 1/26$660

Find flight deals from Frankfurt to Panama City

Discover tips and strategies to find the most affordable flight options for your journey from Frankfurt (FRA) to Panama City (ECP). Learn about various techniques such as flexible date searches, comparing prices across and setting up price alerts. Use these methods to find the cheapest flights available for your travel needs. Data last updated January 26, 2026.

Most accurate provider

FlightHub
3 stars

Most trusted provider

FlightHub
3 stars

Round-trip from

$637
(American Airlines)

Popular in

January

Cheapest in

September

Average price

$1,015
Provider with most accurate pricing for Frankfurt am Main-Panama City NW Florida Beaches flight deals.
Search Deals
Provider most trusted by Cheapflights users for Frankfurt am Main-Panama City NW Florida Beaches flights.
Search Deals
From Frankfurt am Main to Panama City NW Florida Beaches
Search Deals
Highest demand for flights based on searches. 10% potential increase in price ($90 potential increase over avg. RT price).
Search Deals
Cheapest flight prices on average. 3% potential price decrease ($23 potential savings vs. average RT price).
Search Deals
Average for round-trip flights in January 2026
Search Deals

Cheapflights Fare Finder

 
Customize your flight search to find flights from Frankfurt to Panama City that fit within your specific budget. Explore options based on user searches and filter the results based on your desired price range. Find flights that match your budget for a cost-effective journey. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated January 26, 2026.
Use the filters below to find and compare flights from Frankfurt am Main Airport to Panama City that are best for you.

Fly from

Frankfurt

Fly to

Panama City

Route

Depart

Return

Price

Frankfurt am MainPanama City

FRA - ECP

FRAECP

Frankfurt am Main

Mon 2/23

10:15 am-11:49 pm

2 stops20h 34m

Panama City NW Florida Beaches

Mon 3/2

3:38 pm-6:10 pm

2 stops19h 32m

$641

Frankfurt am MainPanama City

FRA - ECP

FRAECP

Frankfurt am Main

Thu 2/5

10:15 am-1:04 pm

2 stops33h 49m

Panama City NW Florida Beaches

Sun 2/8

1:34 pm-7:15 am

2 stops34h 41m

$652

Frankfurt am MainPanama City

FRA - ECP

FRAECP

Frankfurt am Main

Mon 5/4

2:15 pm-11:12 pm

2 stops15h 57m

Panama City NW Florida Beaches

Tue 5/26

6:00 am-8:40 am

2 stops19h 40m

$684

Frankfurt am MainPanama City

FRA - ECP

FRAECP

Frankfurt am Main

Thu 3/26

1:50 pm-4:11 pm

1 stop32h 21m

Panama City NW Florida Beaches

Wed 4/8

10:10 am-11:15 am

1 stop18h 05m

$724

Frankfurt am MainPanama City

FRA - ECP

FRAECP

Frankfurt am Main

Thu 2/5

1:50 pm-9:59 pm

1 stop15h 09m

Panama City NW Florida Beaches

Sun 2/8

6:30 am-6:35 am

2 stops17h 05m

$724

Frankfurt am MainPanama City

FRA - ECP

FRAECP

Frankfurt am Main

Thu 6/18

10:40 am-8:17 am

1 stop28h 37m

Panama City NW Florida Beaches

Sun 6/28

12:05 pm-9:50 am

1 stop14h 45m

$754

Frankfurt am MainPanama City

FRA - ECP

FRAECP

Frankfurt am Main

Mon 3/30

1:55 pm-9:59 pm

1 stop15h 04m

Panama City NW Florida Beaches

Fri 4/10

6:30 am-11:15 am

1 stop21h 45m

$771

Frankfurt am MainPanama City

FRA - ECP

FRAECP

Frankfurt am Main

Sun 3/29

8:50 am-9:35 am

2 stops31h 45m

Panama City NW Florida Beaches

Wed 4/8

6:30 am-8:55 am

2 stops19h 25m

$771

Frankfurt am MainPanama City

FRA - ECP

FRAECP

Frankfurt am Main

Mon 3/30

1:55 pm-9:59 pm

1 stop15h 04m

Panama City NW Florida Beaches

Sun 4/12

2:19 pm-6:30 am

1 stop33h 11m

$771

Flights are sorted by cheapest round-trip flights first.

Deals found on 1/26

  • Most accurate provider: When it comes to deals on Frankfurt am Main Airport-Panama City, Florida flights, users find the pricing of FlightHub to be most consistent on Cheapflights vs. FlightHub Users can find the same prices on Frankfurt am Main Airport-Panama City, Florida flight deals on Cheapflights vs. FlightHub >95% of the time. Price accuracy is based on data collected from Frankfurt am Main Airport-Panama City, Florida flight searches over the past month and is updated monthly.
  • Most trusted provider: When it comes to deals on Frankfurt am Main Airport-Panama City, Florida flights, Cheapflights users trust FlightHub the most. FlightHub has received a user feedback score of 3 out of 3 stars (3 being the best), meaning they have been trusted the most by Cheapflights users looking for Frankfurt am Main Airport-Panama City, Florida flight deals. Provider user feedback score is based on Cheapflights searches over the past month and is updated monthly.

Best time to book a flight from Frankfurt to Panama City

Have a flexible travel schedule? Discover the best time to fly to Panama City from Frankfurt with our price prediction graph.
Estimated round-trip price
Rates are based on past data. Find the cheapest month and day to book your flight based on your travel requirements, then search for cheap deals.

Cheapflights Insights

Everything you need to know about your flight from Frankfurt am Main Airport to Panama City

What is the cheapest month to book a flight from Frankfurt am Main Airport to Panama City, Florida?

Currently, July is the cheapest month in which you can book a flight from Frankfurt am Main Airport to Panama City, Florida (average of $448). Flying from Frankfurt am Main Airport to Panama City, Florida in December is currently the most expensive (average of $674). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.

Related info for your journey

Find useful and relevant information for your journey from Frankfurt to Panama City. Access travel guides, tips, and recommendations to enhance your travel experience. Get information about local attractions, weather, transportation options, and more.

  • What airport do you fly into for flights to Panama City from Frankfurt am Main?

    For a flight from Frankfurt am Main to Panama City, you will be flying into NW Florida Beaches. Panama City NW Florida Beaches (ECP) is just 16.0 mi from the center of the city. NW Florida Beaches is the only Panama City airport and it handles 0 inbound flights from Frankfurt am Main per day. 0 airlines have flights to Panama City NW Florida Beaches from Frankfurt am Main on a regular basis.

  • How long is the flight from Frankfurt am Main Airport to Panama City, Florida?

    Airlines like American Airlines and Delta fly from Frankfurt am Main Airport to Panama City, Florida in about 15h 57m. The time it takes to get you to your destination can typically vary by up to 4h 37m. Frankfurt am Main Airport and Panama City, Florida are separated by a distance of 4819 mi. When browsing for deals, the options you’ll see will be for both nonstop flights and flights with stops.

  • Can I find deals for flights from Frankfurt to Panama City that include hotel bookings?

    Yes. In addition to deals on Frankfurt to Panama City flights, Cheapflights offers vacation packages that include both flights and hotel.

  • How can I find direct flights from Frankfurt to Panama City?

    After entering your origin and destination, apply the non-stop filter on the search result page to find direct flights from Frankfurt to Panama City.

  • Can I find deals for business class flights from Frankfurt to Panama City?

    Yes. Cheapflights offers flight deals from Frankfurt to Panama City by cabin class. In addition to browsing deals, you can also filter by cabin class on the search results page after making a search.

  • What is the cheapest month to book a flight from Frankfurt am Main Airport to Panama City, Florida?

    Currently, July is the cheapest month in which you can book a flight from Frankfurt am Main Airport to Panama City, Florida (average of $448). Flying from Frankfurt am Main Airport to Panama City, Florida in December is currently the most expensive (average of $674). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.

See more FAQs

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