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Panama City

$88+ Cheap flights from Florida Keys to Panama City, FL (ECP)

This is the cheapest one-way flight price found by a Cheapflights user in the last 72 hours by searching for a flight departing on 11/5. Fares are subject to change and may not be available on all flights or dates of travel.
EYW — ECP
Aug 21 — Aug 281
Thu 8/21
Thu 8/28
1 adult, Economy
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Cheap flight deals from Florida Keys to Panama City

Keep the following information in mind while searching for Florida Keys to Panama City flight deals. Data was last updated August 16, 2025.

Round-trip from

$186
(Delta)

One-way from

$88
(Delta)
From Florida Keys to Panama City NW Florida Beaches
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One-way flight from Florida Keys to Panama City NW Florida Beaches
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Find flight deals from Florida Keys to Panama City

Cheapest flights from Florida Keys to Panama City
Explore the most affordable flight options available from Florida Keys to Panama City. Find the lowest fares from popular airlines and budget airlines, with prices last updated on August 16, 2025.

This Delta deal was found by Cheapflights users on 8/14. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 9/47:30 pmMIA - ECP
1 stop4h 36mDelta
Wed 9/105:02 pmECP - MIA
1 stop6h 22mDelta
Deal found 8/14$186
This Delta deal was found by Cheapflights users on 8/14. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 9/66:00 amMIA - ECP
1 stop4h 55mDelta
Mon 9/86:00 amECP - MIA
1 stop3h 52mDelta
Deal found 8/14$197
This Southwest deal was found by Cheapflights users on 8/14. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 9/135:50 amMIA - ECP
1 stop8h 20mSouthwest
Sat 9/209:45 amECP - MIA
2 stops9h 50mSouthwest
Deal found 8/14$202
This Delta deal was found by Cheapflights users on 8/13. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 9/104:25 pmMIA - ECP
1 stop4h 23mDelta
Wed 9/242:05 pmECP - MIA
1 stop6h 18mDelta
Deal found 8/13$237
This Delta deal was found by Cheapflights users on 8/14. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 9/227:38 pmMIA - ECP
1 stop4h 25mDelta
Thu 9/254:46 pmECP - MIA
1 stop6h 37mDelta
Deal found 8/14$252
This Southwest deal was found by Cheapflights users on 8/14. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 9/44:40 pmMIA - ECP
1 stop5h 20mSouthwest
Wed 9/107:40 amECP - MIA
2 stops8h 00mSouthwest
Deal found 8/14$281
This Delta deal was found by Cheapflights users on 8/14. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 9/127:38 pmMIA - ECP
1 stop4h 25mDelta
Sun 9/146:00 amECP - MIA
1 stop4h 01mDelta
Deal found 8/14$287
This American Airlines deal was found by Cheapflights users on 8/14. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 9/145:18 amMIA - ECP
1 stop5h 24mAmerican Airlines
Sun 9/216:59 pmECP - MIA
1 stop4h 35mAmerican Airlines
Deal found 8/14$293
This Delta deal was found by Cheapflights users on 8/15. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 9/227:38 pmMIA - ECP
1 stop4h 25mDelta
Tue 9/306:00 amECP - MIA
1 stop6h 28mDelta
Deal found 8/15$296
This Delta deal was found by Cheapflights users on 8/14. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 9/136:10 pmEYW - ECP
1 stop5h 53mDelta
Tue 9/166:00 amECP - EYW
1 stop3h 55mDelta
Deal found 8/14$297
This Southwest deal was found by Cheapflights users on 8/14. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 9/66:05 amMIA - ECP
2 stops9h 35mSouthwest
Mon 9/811:25 amECP - MIA
2 stops9h 45mSouthwest
Deal found 8/14$297
This American Airlines deal was found by Cheapflights users on 8/15. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 9/1312:00 pmEYW - ECP
2 stops10h 12mAmerican Airlines
Tue 9/166:32 amECP - EYW
2 stops11h 27mAmerican Airlines
Deal found 8/15$1,049

Cheapflights Fare Finder

 
Customize your flight search to find flights from Florida Keys to Panama City that fit within your specific budget. Explore options based on user searches and filter the results based on your desired price range. Find flights that match your budget for a cost-effective journey. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated August 16, 2025.
Use the filters below to find and compare flights from Florida Keys to Panama City that are best for you.

Fly from

Florida Keys

Fly to

Panama City

Route

Depart

Return

Price

MiamiPanama City

MIA - ECP

MIAECP

Miami

Thu 9/4

7:30 pm-11:06 pm

1 stop4h 36m

Panama City NW Florida Beaches

Wed 9/10

5:02 pm-12:24 am

1 stop6h 22m

$186

MiamiPanama City

MIA - ECP

MIAECP

Miami

Mon 9/8

7:05 am-11:31 am

1 stop5h 26m

Panama City NW Florida Beaches

Thu 9/11

2:29 pm-11:15 pm

1 stop7h 46m

$197

MiamiPanama City

MIA - ECP

MIAECP

Miami

Mon 9/22

7:38 pm-11:03 pm

1 stop4h 25m

Panama City NW Florida Beaches

Thu 9/25

6:54 pm-12:23 am

1 stop4h 29m

$197

MiamiPanama City

MIA - ECP

MIAECP

Miami

Sat 9/6

6:00 am-9:55 am

1 stop4h 55m

Panama City NW Florida Beaches

Mon 9/8

6:00 am-10:52 am

1 stop3h 52m

$197

MiamiPanama City

MIA - ECP

MIAECP

Miami

Sat 9/13

5:50 am-1:10 pm

1 stop8h 20m

Panama City NW Florida Beaches

Sat 9/20

9:45 am-8:35 pm

2 stops9h 50m

$202

MiamiPanama City

MIA - ECP

MIAECP

Miami

Wed 9/10

4:25 pm-7:48 pm

1 stop4h 23m

Panama City NW Florida Beaches

Wed 9/24

2:05 pm-9:23 pm

1 stop6h 18m

$237

MiamiPanama City

MIA - ECP

MIAECP

Miami

Thu 9/4

4:40 pm-9:00 pm

1 stop5h 20m

Panama City NW Florida Beaches

Wed 9/10

7:40 am-4:40 pm

2 stops8h 00m

$281

MiamiPanama City

MIA - ECP

MIAECP

Miami

Tue 10/7

4:35 pm-7:55 pm

1 stop4h 20m

Panama City NW Florida Beaches

Fri 10/10

6:17 pm-11:09 pm

1 stop3h 52m

$286

Key WestPanama City

EYW - ECP

EYWECP

Key West

Sat 9/13

6:10 pm-11:03 pm

1 stop5h 53m

Panama City NW Florida Beaches

Tue 9/16

6:00 am-10:55 am

1 stop3h 55m

$297

Key WestPanama City

EYW - ECP

EYWECP

Key West

Sat 9/13

12:00 pm-9:12 pm

2 stops10h 12m

Panama City NW Florida Beaches

Tue 9/16

6:32 am-6:59 pm

2 stops11h 27m

$1,049

Flights are sorted by cheapest round-trip flights first.

Deals found on 8/14

Showing 1-10 of 21 results
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2
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Best time to book a flight from Florida Keys to Panama City

Have a flexible travel schedule? Discover the best time to fly to Panama City from Florida Keys with our price prediction graph.
Estimated round-trip price
Rates are based on past data. Find the cheapest month and day to book your flight based on your travel requirements, then search for cheap deals.

Cheapflights Insights

Everything you need to know about your flight from Florida Keys to Panama City

What is the cheapest month to book a flight from Florida Keys to Panama City, Florida?

Currently, January is the cheapest month in which you can book a flight from Florida Keys to Panama City, Florida (average of $346). Flying from Florida Keys to Panama City, Florida in March is currently the most expensive (average of $460). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.

Reviews of airlines servicing Panama City

Get insights into the airlines that provide service to Panama City. Read reviews, discover amenities, and learn about the overall travel experience offered by airlines. Use this information to make informed decisions when choosing an airline for your flight to Panama City. Reviews last updated August 16, 2025.
See what other customers who have flown with Delta and American Airlines from Florida Keys to Panama City have to say. You can also see how each airline stacks up in terms of entertainment options, comfort, food, crew/service, and boarding process.
Delta
8.0
Very good
7,985 reviews

Food

7.3

Crew

8.5

Boarding

8.2

Overall

8.0

Comfort

7.9

Entertainment

7.9

Reviews

1 / 20
6.0
Good

pilar,May 2025

RSW - ATL

The stewardess was not very nice because I requested two glasses of water. She didn’t even offer the snacks to me. She seemed angry and I felt very bad about her reaction. Also, the flight was full and you could not move. The airline should provide seats for obese people in consideration to the rest pf the passengers.
Delta
8.0
Very good
7,985 reviews
Delta
8.0
Very good
7,985 reviews

Food

7.3

Crew

8.5

Boarding

8.2

Overall

8.0

Comfort

7.9

Entertainment

7.9

Reviews

1 / 20
6.0
Good

pilar,May 2025

RSW - ATL

The stewardess was not very nice because I requested two glasses of water. She didn’t even offer the snacks to me. She seemed angry and I felt very bad about her reaction. Also, the flight was full and you could not move. The airline should provide seats for obese people in consideration to the rest pf the passengers.
American Airlines
7.2
Good
10,000 reviews
Delta
8.0
Very good
7,985 reviews

Food

7.3

Crew

8.5

Boarding

8.2

Overall

8.0

Comfort

7.9

Entertainment

7.9

Reviews

1 / 20
6.0
Good

pilar,May 2025

RSW - ATL

The stewardess was not very nice because I requested two glasses of water. She didn’t even offer the snacks to me. She seemed angry and I felt very bad about her reaction. Also, the flight was full and you could not move. The airline should provide seats for obese people in consideration to the rest pf the passengers.

Related info for your journey

Find useful and relevant information for your journey from Florida Keys to Panama City. Access travel guides, tips, and recommendations to enhance your travel experience. Get information about local attractions, weather, transportation options, and more.

  • What airport do you fly into for flights to Panama City from Florida Keys?

    Most people fly into Panama City NW Florida Beaches (ECP) if they book a flight to Panama City from Florida Keys. NW Florida Beaches is conveniently located just 16.0 mi from Panama City’s city center.

  • Can I find deals for flights from Florida Keys to Panama City that include hotel bookings?

    Yes. In addition to deals on Florida Keys to Panama City flights, Cheapflights offers vacation packages that include both flights and hotel.

  • How can I find direct flights from Florida Keys to Panama City?

    After entering your origin and destination, apply the non-stop filter on the search result page to find direct flights from Florida Keys to Panama City.

  • Can I find deals for business class flights from Florida Keys to Panama City?

    Yes. Cheapflights offers flight deals from Florida Keys to Panama City by cabin class. In addition to browsing deals, you can also filter by cabin class on the search results page after making a search.

  • What is the cheapest month to book a flight from Florida Keys to Panama City, Florida?

    Currently, January is the cheapest month in which you can book a flight from Florida Keys to Panama City, Florida (average of $346). Flying from Florida Keys to Panama City, Florida in March is currently the most expensive (average of $460). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.

See more FAQs

Traveling to a place near Panama City?

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