$116+ Cheap flights from Detroit Metropolitan Wayne County Airport to Panama City, FL (DTW - ECP)
This is the cheapest round-trip flight price found by a Cheapflights user in the last 72 hours by searching for a flight departing on 1/5. Fares are subject to change and may not be available on all flights or dates of travel.
DTW — ECP
Nov 24 — Dec 11
Round-trip
1 adult, Economy
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Find cheap flights from Detroit to Panama City with Cheapflights
1. Tell us where you want to go
Enter your travel information like dates, passengers, trip type (one-way or round trip), and preferred cabin class then click “Find deals”2. Select your favorite providers
We find the providers serving your travel needs. Choose up to four travel providers to compare side-by-side for flights, hotels, or car rentals.3. Compare prices and book
Review each provider’s pricing and select the best option for you! Book through your favorite provider’s website for a seamless experience.Cheap flight deals from Detroit to Panama City
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Cheapest flights from Detroit to Panama CityExplore the most affordable flight options available from Detroit to Panama City. Find the lowest fares from popular airlines and budget airlines, with prices last updated on October 25, 2026.
Explore the most affordable flight options available from Detroit to Panama City. Find the lowest fares from popular airlines and budget airlines, with prices last updated on October 25, 2026.
This American Airlines deal was found by Cheapflights users on 10/23. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 11/146:25 pm -
1 stop5h 27m
Tue 11/178:19 am -
1 stop6h 24m
Deal found 10/23![American Airlines logo]()
$231
This Southwest deal was found by Cheapflights users on 10/22. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 12/215:40 am -
1 stop4h 40m
Tue 1/57:55 am -
2 stops11h 35m
Deal found 10/22![Southwest logo]()
$242
This American Airlines deal was found by Cheapflights users on 10/21. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 11/187:43 am -
1 stop4h 47m
Wed 11/256:49 pm -
1 stop4h 45m
Deal found 10/21![American Airlines logo]()
$248
This Delta deal was found by Cheapflights users on 10/23. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 11/164:25 pm -
1 stop5h 32m
Tue 11/246:00 am -
1 stop6h 04m
Deal found 10/23![Delta logo]()
$249
This American Airlines deal was found by Cheapflights users on 10/21. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 11/276:00 am -
1 stop5h 39m
Tue 12/16:49 pm -
1 stop4h 45m
Deal found 10/21![American Airlines logo]()
$261
This Southwest deal was found by Cheapflights users on 10/23. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 11/146:10 am -
1 stop4h 20m
Tue 11/177:30 am -
2 stops9h 30m
Deal found 10/23![Southwest logo]()
$263
This Southwest deal was found by Cheapflights users on 10/20. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected ” under the list of providers to see comparable flight deals.
Fri 12/41:25 pm -
1 stop5h 50m
Tue 12/1510:05 am -
2 stops10h 20m
Deal found 10/20![Southwest logo]()
$266
This United Airlines deal was found by Cheapflights users on 10/21. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 11/186:15 am -
2 stops11h 03m
Wed 11/253:05 pm -
1 stop6h 22m
Deal found 10/21![United Airlines logo]()
$278
This Delta deal was found by Cheapflights users on 10/23. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 11/137:48 pm -
1 stop4h 36m
Tue 11/176:00 am -
1 stop4h 30m
Deal found 10/23![Delta logo]()
$279
This Delta deal was found by Cheapflights users on 10/23. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 12/139:08 am -
1 stop6h 53m
Mon 12/146:59 pm -
1 stop4h 57m
Deal found 10/23![Delta logo]()
$294
This United Airlines deal was found by Cheapflights users on 10/20. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 11/175:45 am -
2 stops9h 43m
Tue 11/243:05 pm -
1 stop6h 22m
Deal found 10/20![United Airlines logo]()
$297
This American Airlines deal was found by Cheapflights users on 10/23. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 11/76:25 pm -
1 stop5h 27m
Wed 11/115:41 pm -
1 stop4h 47m
Deal found 10/23![American Airlines logo]()
$307
Best flights from Detroit to Panama CityDiscover carefully curated flight deals from Detroit to Panama City that have cost, travel time, and layovers in mind to ensure you get the best travel experience. Data last updated October 25, 2026.
Discover carefully curated flight deals from Detroit to Panama City that have cost, travel time, and layovers in mind to ensure you get the best travel experience. Data last updated October 25, 2026.
This United Airlines deal was found by Cheapflights users on 10/23. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 11/76:15 am -
2 stops11h 03m
Wed 11/113:05 pm -
1 stop6h 22m
Deal found 10/23![United Airlines logo]()
$312
This Delta deal was found by Cheapflights users on 10/22. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 12/236:25 am -
1 stop4h 50m
Tue 1/56:00 am -
1 stop4h 22m
Deal found 10/22![Delta logo]()
$312
This Southwest deal was found by Cheapflights users on 10/24. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 12/215:40 am -
1 stop4h 40m
Fri 12/254:10 pm -
1 stop4h 15m
Deal found 10/24![Southwest logo]()
$339
This United Airlines deal was found by Cheapflights users on 10/21. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 1/98:35 am -
1 stop6h 46m
Wed 1/132:56 pm -
1 stop6h 49m
Deal found 10/21![United Airlines logo]()
$331
This United Airlines deal was found by Cheapflights users on 10/22. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 12/511:08 am -
2 stops11h 30m
Tue 12/159:05 am -
2 stops10h 47m
Deal found 10/22![United Airlines logo]()
$383
This Southwest deal was found by Cheapflights users on 10/24. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 12/66:50 am -
2 stops8h 35m
Sun 12/137:00 am -
2 stops9h 15m
Deal found 10/24![Southwest logo]()
$430
This Southwest deal was found by Cheapflights users on 10/24. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 12/256:00 am -
1 stop4h 30m
Mon 1/411:25 am -
1 stop7h 10m
Deal found 10/24![Southwest logo]()
$443
This Southwest deal was found by Cheapflights users on 10/24. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 12/106:55 am -
2 stops9h 15m
Sun 12/137:00 am -
2 stops9h 15m
Deal found 10/24![Southwest logo]()
$444
Last-minute flights from Detroit to Panama CityDiscover last-minute flight deals from Detroit to Panama City. Data last updated October 25, 2026 and is based on user searches.
Discover last-minute flight deals from Detroit to Panama City. Data last updated October 25, 2026 and is based on user searches.
This American Airlines deal was found by Cheapflights users on 10/23. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 11/76:25 pm -
1 stop5h 27m
Wed 11/115:41 pm -
1 stop4h 47m
Deal found 10/23![American Airlines logo]()
$307
This Delta deal was found by Cheapflights users on 10/23. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 11/125:20 am -
1 stop4h 25m
Thu 11/121:34 pm -
1 stop6h 39m
Deal found 10/23![Delta logo]()
$314
This Delta deal was found by Cheapflights users on 10/23. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 11/137:48 pm -
1 stop4h 36m
Tue 11/176:00 am -
1 stop4h 30m
Deal found 10/23![Delta logo]()
$279
This American Airlines deal was found by Cheapflights users on 10/23. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 11/146:25 pm -
1 stop5h 27m
Tue 11/178:19 am -
1 stop6h 24m
Deal found 10/23![American Airlines logo]()
$231
This Southwest deal was found by Cheapflights users on 10/23. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 11/146:10 am -
1 stop4h 20m
Tue 11/177:30 am -
2 stops9h 30m
Deal found 10/23![Southwest logo]()
$263
This Delta deal was found by Cheapflights users on 10/23. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 11/155:20 am -
1 stop6h 10m
Tue 11/175:16 pm -
1 stop6h 41m
Deal found 10/23![Delta logo]()
$294
This Delta deal was found by Cheapflights users on 10/23. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 11/167:48 pm -
1 stop4h 36m
Mon 11/235:16 pm -
1 stop4h 00m
Deal found 10/23![Delta logo]()
$249
This United Airlines deal was found by Cheapflights users on 10/20. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 11/175:45 am -
2 stops9h 43m
Tue 11/243:05 pm -
1 stop6h 22m
Deal found 10/20![United Airlines logo]()
$297
This American Airlines deal was found by Cheapflights users on 10/21. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 11/187:43 am -
1 stop4h 47m
Wed 11/256:49 pm -
1 stop4h 45m
Deal found 10/21![American Airlines logo]()
$248
This United Airlines deal was found by Cheapflights users on 10/21. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 11/186:15 am -
2 stops11h 03m
Wed 11/253:05 pm -
1 stop6h 22m
Deal found 10/21![United Airlines logo]()
$278
This Delta deal was found by Cheapflights users on 10/23. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 11/225:20 am -
1 stop4h 25m
Mon 11/235:16 pm -
1 stop4h 00m
Deal found 10/23![Delta logo]()
$312
This American Airlines deal was found by Cheapflights users on 10/21. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 11/276:00 am -
1 stop5h 39m
Tue 12/16:49 pm -
1 stop4h 45m
Deal found 10/21![American Airlines logo]()
$261
One-way flights from Detroit to Panama CitySearch for one-way flight options from Detroit to Panama City. Find affordable one-way fares based on user searches. Data last updated October 25, 2026.
Search for one-way flight options from Detroit to Panama City. Find affordable one-way fares based on user searches. Data last updated October 25, 2026.
This Southwest deal was found by Cheapflights users on 10/22. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 1/56:00 am -
1 stop4h 30m
Wed 12/3112:00 am -
Nonstop0h 00m
Deal found 10/22![Southwest logo]()
$116
This Delta deal was found by Cheapflights users on 10/19. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 12/191:43 pm -
1 stop6h 53m
Wed 12/3112:00 am -
Nonstop0h 00m
Deal found 10/19![Delta logo]()
$134
This Southwest deal was found by Cheapflights users on 10/22. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 1/16:00 am -
1 stop4h 30m
Wed 12/3112:00 am -
Nonstop0h 00m
Deal found 10/22![Southwest logo]()
$146
This Delta deal was found by Cheapflights users on 10/20. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 11/237:48 pm -
1 stop4h 36m
Wed 12/3112:00 am -
Nonstop0h 00m
Deal found 10/20![Delta logo]()
$170
This Delta deal was found by Cheapflights users on 10/22. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 11/225:20 am -
1 stop4h 25m
Wed 12/3112:00 am -
Nonstop0h 00m
Deal found 10/22![Delta logo]()
$188
This American Airlines deal was found by Cheapflights users on 10/21. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 11/227:43 pm -
1 stop5h 04m
Wed 12/3112:00 am -
Nonstop0h 00m
Deal found 10/21![American Airlines logo]()
$192
This Delta deal was found by Cheapflights users on 10/20. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 11/45:20 am -
1 stop3h 54m
Wed 12/3112:00 am -
Nonstop0h 00m
Deal found 10/20![Delta logo]()
$201
This Southwest deal was found by Cheapflights users on 10/19. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 12/225:40 am -
1 stop4h 40m
Wed 12/3112:00 am -
Nonstop0h 00m
Deal found 10/19![Southwest logo]()
$215
This Southwest deal was found by Cheapflights users on 10/19. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 12/195:40 am -
2 stops13h 20m
Wed 12/3112:00 am -
Nonstop0h 00m
Deal found 10/19![Southwest logo]()
$240
Find flight deals from Detroit to Panama City
Discover tips and strategies to find the most affordable flight options for your journey from Detroit (DTW) to Panama City (ECP). Learn about various techniques such as flexible date searches, comparing prices across and setting up price alerts. Use these methods to find the cheapest flights available for your travel needs. Data last updated October 25, 2026.
Most accurate provider | FlightHub 3 stars |
|---|---|
Most trusted provider | FlightHub 3 stars |
Round-trip from | $231 (American Airlines) |
One-way from | $116 (Southwest) |
Popular in | March |
Cheapest in | January |
Average price | $343 |
Cheapflights Fare Finder
Customize your flight search to find flights from Detroit to Panama City that fit within your specific budget. Explore options based on user searches and filter the results based on your desired price range. Find flights that match your budget for a cost-effective journey. Over the last 7 days, Cheapflights users made 7,457,451 searches. Data last updated October 25, 2026.
Use the filters below to find and compare flights from Detroit Metropolitan Wayne County Airport to Panama City that are best for you.
Fly from
Fly to
Route
Depart
Return
Cheapest round-trip
DetroitPanama City
DTW Detroit Metropolitan Wayne County - ECP Panama City NW Florida Beaches
DTWECP
Detroit Metropolitan Wayne County
Tue 1/5
8:50 am-6:15 pm
2 stops10h 25m
Panama City NW Florida Beaches
Wed 12/31
12:00 am-1:00 am
Nonstop0h 00m
$127
DetroitPanama City
DTW Detroit Metropolitan Wayne County - ECP Panama City NW Florida Beaches
DTWECP
Detroit Metropolitan Wayne County
Sat 12/19
1:43 pm-7:36 pm
1 stop6h 53m
Panama City NW Florida Beaches
Wed 12/31
12:00 am-1:00 am
Nonstop0h 00m
$134
DetroitPanama City
DTW Detroit Metropolitan Wayne County - ECP Panama City NW Florida Beaches
DTWECP
Detroit Metropolitan Wayne County
Fri 1/1
6:00 am-9:30 am
1 stop4h 30m
Panama City NW Florida Beaches
Wed 12/31
12:00 am-1:00 am
Nonstop0h 00m
$146
DetroitPanama City
DTW Detroit Metropolitan Wayne County - ECP Panama City NW Florida Beaches
DTWECP
Detroit Metropolitan Wayne County
Sun 11/22
5:20 am-8:45 am
1 stop4h 25m
Panama City NW Florida Beaches
Wed 12/31
12:00 am-1:00 am
Nonstop0h 00m
$188
DetroitPanama City
DTW Detroit Metropolitan Wayne County - ECP Panama City NW Florida Beaches
DTWECP
Detroit Metropolitan Wayne County
Sun 11/22
7:43 pm-11:47 pm
1 stop5h 04m
Panama City NW Florida Beaches
Wed 12/31
12:00 am-1:00 am
Nonstop0h 00m
$192
Quickest round-trip
DetroitPanama City
DTW Detroit Metropolitan Wayne County - ECP Panama City NW Florida Beaches
DTWECP
Detroit Metropolitan Wayne County
Wed 11/4
5:20 am-8:14 am
1 stop3h 54m
Panama City NW Florida Beaches
Wed 12/31
12:00 am-1:00 am
Nonstop0h 00m
$201
DetroitPanama City
DTW Detroit Metropolitan Wayne County - ECP Panama City NW Florida Beaches
DTWECP
Detroit Metropolitan Wayne County
Tue 12/22
5:40 am-9:20 am
1 stop4h 40m
Panama City NW Florida Beaches
Wed 12/31
12:00 am-1:00 am
Nonstop0h 00m
$215
DetroitPanama City
DTW Detroit Metropolitan Wayne County - ECP Panama City NW Florida Beaches
DTWECP
Detroit Metropolitan Wayne County
Wed 11/4
6:00 am-3:10 pm
2 stops10h 10m
Panama City NW Florida Beaches
Wed 12/31
12:00 am-1:00 am
Nonstop0h 00m
$255
DetroitPanama City
DTW Detroit Metropolitan Wayne County - ECP Panama City NW Florida Beaches
DTWECP
Detroit Metropolitan Wayne County
Sat 11/7
6:15 am-4:18 pm
2 stops11h 03m
Panama City NW Florida Beaches
Wed 11/11
3:05 pm-10:27 pm
1 stop6h 22m
$312
DetroitPanama City
DTW Detroit Metropolitan Wayne County - ECP Panama City NW Florida Beaches
DTWECP
Detroit Metropolitan Wayne County
Wed 12/23
6:25 am-10:15 am
1 stop4h 50m
Panama City NW Florida Beaches
Tue 1/5
6:00 am-11:22 am
1 stop4h 22m
$312
Showing 1-10 of 18 resultsSorted by cheapest first
Compare providers for flights from Detroit to Panama City
Provider information is updated monthly. Please note that these providers often have deals for this flight, but the availability may vary on a day-by-day basis on Cheapflights.
Use the table below to compare price accuracy, trust ratings, and cancellation policies for each provider offering flight deals from Detroit to Panama City in October.
| Provider | Price Accuracy | Trust Score* |
|---|---|---|
| Price Accuracy1 star | Trust Score*3 stars | |
| Price Accuracy3 stars | Trust Score*3 stars |
- Most accurate provider: When it comes to deals on Detroit Metropolitan Wayne County Airport-Panama City, Florida flights, users find the pricing of FlightHub to be most consistent on Cheapflights vs. FlightHub Users can find the same prices on Detroit Metropolitan Wayne County Airport-Panama City, Florida flight deals on Cheapflights vs. FlightHub >95% of the time. Price accuracy is based on data collected from Detroit Metropolitan Wayne County Airport-Panama City, Florida flight searches over the past month and is updated monthly.
- Most trusted provider: When it comes to deals on Detroit Metropolitan Wayne County Airport-Panama City, Florida flights, Cheapflights users trust FlightHub the most. FlightHub has received a user feedback score of 3 out of 3 stars (3 being the best), meaning they have been trusted the most by Cheapflights users looking for Detroit Metropolitan Wayne County Airport-Panama City, Florida flight deals. Provider user feedback score is based on Cheapflights searches over the past month and is updated monthly.
Best time to book a flight from Detroit to Panama City
Have a flexible travel schedule? Discover the best time to fly to Panama City from Detroit with our price prediction graph.
DTW-ECP
Estimated round-trip price
Rates are based on past data. Find the cheapest month and day to book your flight based on your travel requirements, then search for cheap deals.
Cheapflights Insights
Everything you need to know about your flight from Detroit Metropolitan Wayne County Airport to Panama City
Prices
More
How far ahead should I book a flight from Detroit Metropolitan Wayne County Airport to Panama City, Florida?
The price you pay for your flight from Detroit Metropolitan Wayne County Airport to Panama City, Florida may vary depending on when you book. For the best chance of a lower fare, look to book 87 days in advance of your trip. Fares are likely to increase a fortnight or so before your departure date.
What is the cheapest month to book a flight from Detroit Metropolitan Wayne County Airport to Panama City, Florida?
Currently, January is the cheapest month in which you can book a flight from Detroit Metropolitan Wayne County Airport to Panama City, Florida (average of $285). Flying from Detroit Metropolitan Wayne County Airport to Panama City, Florida in March is currently the most expensive (average of $780). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.
How much does it cost to fly round-trip from Detroit Metropolitan Wayne County Airport to Panama City, Florida?
Airfare is below average for this route at the moment.
Detroit Metropolitan Wayne County Airport to Panama City, Florida flights typically cost between $344 and $603 in November.The cheapest round-trip price found within the last 5 days was $231 on American Airlines (Nov 14-Nov 17).
What’s the top layover airport for flights from Detroit Metropolitan Wayne County Airport to Panama City, Florida?
Share of 1-stop round-trip flights from Detroit Metropolitan Wayne County Airport to Panama City, Florida chosen by Cheapflights users in the past 12 months, using the same layover each way.
Nashville (BNA) – chosen by Cheapflights users on 44% of 1-stop itineraries from Detroit Metropolitan Wayne County Airport to Panama City, Florida on Cheapflights.
What’s the cheapest layover airport for flights from Detroit Metropolitan Wayne County Airport to Panama City, Florida?
Average round-trip fare for 1-stop flights from Detroit Metropolitan Wayne County Airport to Panama City, Florida, chosen by Cheapflights users in the past 12 months, with the same layover each way.
Charlotte (CLT) is the most affordable 1-stop option, with an average round-trip price of $314.
What’s the fastest layover option from Detroit Metropolitan Wayne County Airport to Panama City, Florida?
Shortest average travel time for 1-stop one-way flights from Detroit Metropolitan Wayne County Airport to Panama City, Florida, based on itineraries clicked by Cheapflights users over the past 12 months, grouped by layover airport.
Flights via Charlotte (CLT) have the shortest average one-way travel time for 1-stop routes: 4h 59m.
Which airport typically offers the quickest layover for flights from Detroit Metropolitan Wayne County Airport to Panama City, Florida?
Average layover duration for 1-stop one-way flights from Detroit Metropolitan Wayne County Airport to Panama City, Florida, chosen by Cheapflights users in the last 12 months, grouped by stopover airport.
Flights via Charlotte (CLT) offer the fastest connection on this route, with an average layover time of 1h 12m.
Reviews of airlines servicing Panama City
Get insights into the airlines that provide service to Panama City. Read reviews, discover amenities, and learn about the overall travel experience offered by airlines. Use this information to make informed decisions when choosing an airline for your flight to Panama City. Reviews last updated October 25, 2026.
Peruse reviews from past customers who have flown with Southwest,Delta, andUnited Airlines from Detroit Metropolitan Wayne County Airport to Panama City to help guide your decision. You can also see how each airline stacks up in terms of entertainment options, comfort, food, crew/service, and boarding process.
Crew
8.6
Comfort
8.0
Food
7.0
Boarding
8.1
Overall
7.9
Entertainment
7.4
Reviews
1 / 20
8.0
ExcellentPatricia,Oct 2026
DAL - TPA
Crew
8.6
Comfort
8.0
Food
7.0
Boarding
8.1
Overall
7.9
Entertainment
7.4
Reviews
1 / 20
8.0
ExcellentPatricia,Oct 2026
DAL - TPA
Crew
8.6
Comfort
8.0
Food
7.0
Boarding
8.1
Overall
7.9
Entertainment
7.4
Reviews
1 / 20
8.0
ExcellentPatricia,Oct 2026
DAL - TPA
Crew
8.6
Comfort
8.0
Food
7.0
Boarding
8.1
Overall
7.9
Entertainment
7.4
Reviews
1 / 20
8.0
ExcellentPatricia,Oct 2026
DAL - TPA
Crew
8.6
Comfort
8.0
Food
7.0
Boarding
8.1
Overall
7.9
Entertainment
7.4
Reviews
1 / 20
8.0
ExcellentPatricia,Oct 2026
DAL - TPA
Related info for your journey
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Top 4 airlines flying from Detroit to Panama City
Discover the top 4 airlines that operate flights from Detroit to Panama City. Compare their services, reliability, and customer satisfaction ratings to choose the airline that best suits your travel preferences and needs. Over the last 7 days, Cheapflights users made 7,457,451 searches. Data last updated October 25, 2026.
| Airline | Cheapest | Average | Flexibility | On-time |
|---|---|---|---|---|
| Cheapest$239 | Average$388 | FlexibilityNo cancel fee | On-time71% | |
| Cheapest$239 | Average$409 | FlexibilityNo cancel fee | On-timeN/A | |
| Cheapest$258 | Average$457 | FlexibilityNo cancel fee | On-time63% | |
| Cheapest$278 | Average$400 | FlexibilityNo cancel fee | On-time69% |