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Bruxelles-National

$484+ Cheap flights from Knoxville (TYS) to Bruxelles-National (BRU)

This is the cheapest round-trip flight price found by a Cheapflights user in the last 72 hours by searching for a flight departing on 4/8. Fares are subject to change and may not be available on all flights or dates of travel.
TYS — BRU
Jan 25 — Feb 11
Sun 1/25
Sun 2/1
1 adult, Economy
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Cheap flight deals from Knoxville to Bruxelles-National

Best flights from Knoxville to Bruxelles-National
Discover carefully curated flight deals from Knoxville to Bruxelles-National that have cost, travel time, and layovers in mind to ensure you get the best travel experience. Data last updated December 26, 2025.

This United Airlines deal was found by Cheapflights users on 12/24. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 4/82:25 pmTYS - BRU
2 stops23h 35mUnited Airlines
Wed 4/229:25 amBRU - TYS
2 stops43h 04mUnited Airlines
Deal found 12/24$484
This Cheapflightsfares deal was found by Cheapflights users on 12/25. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Cheapflightsfares is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 1/312:25 pmTYS - BRU
1 stop10h 50mLufthansa
Sat 2/711:55 amBRU - TYS
1 stop13h 32mLufthansa
Deal found 12/25$487
This United Airlines deal was found by Cheapflights users on 12/25. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 2/42:25 pmTYS - BRU
2 stops16h 50mUnited Airlines
Sun 2/810:00 amBRU - TYS
2 stops40h 52mUnited Airlines
Deal found 12/25$485

Find flight deals from Knoxville to Bruxelles-National

Discover tips and strategies to find the most affordable flight options for your journey from Knoxville (TYS) to Bruxelles-National (BRU). Learn about various techniques such as flexible date searches, comparing prices across and setting up price alerts. Use these methods to find the cheapest flights available for your travel needs. Data last updated December 26, 2025.

Most accurate provider

eDreams
3 stars

Most trusted provider

eDreams
3 stars

Round-trip from

$484
(United Airlines)
Provider with most accurate pricing for Knoxville McGhee Tyson-Brussels Bruxelles-National flight deals.
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Provider most trusted by Cheapflights users for Knoxville McGhee Tyson-Brussels Bruxelles-National flights.
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From Knoxville McGhee Tyson to Brussels Bruxelles-National
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Cheapflights Fare Finder

 
Customize your flight search to find flights from Knoxville to Bruxelles-National that fit within your specific budget. Explore options based on user searches and filter the results based on your desired price range. Find flights that match your budget for a cost-effective journey. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated December 26, 2025.
Use the filters below to find and compare flights from Knoxville to Brussels Bruxelles-National Airport that are best for you.

Fly from

Knoxville

Fly to

Bruxelles-National

Route

Depart

Return

Price

KnoxvilleBrussels

TYS - BRU

TYSBRU

Knoxville McGhee Tyson

Wed 4/8

2:25 pm-8:00 pm

2 stops23h 35m

Brussels Bruxelles-National

Wed 4/22

9:25 am-10:29 pm

2 stops43h 04m

$484

KnoxvilleBrussels

TYS - BRU

TYSBRU

Knoxville McGhee Tyson

Wed 2/4

2:25 pm-1:15 pm

2 stops16h 50m

Brussels Bruxelles-National

Sun 2/8

10:00 am-8:52 pm

2 stops40h 52m

$485

KnoxvilleBrussels

TYS - BRU

TYSBRU

Knoxville McGhee Tyson

Sat 1/31

2:25 pm-7:15 am

1 stop10h 50m

Brussels Bruxelles-National

Sat 2/7

11:55 am-7:27 pm

1 stop13h 32m

$487

Flights are sorted by cheapest round-trip flights first.

Deals found on 12/24

Compare providers for flights from Knoxville to Bruxelles-National

Provider information is updated monthly. Please note that these providers often have deals for this flight, but the availability may vary on a day-by-day basis on Cheapflights.
Use the table below to compare price accuracy, trust ratings, and cancellation policies for each provider offering flight deals from Knoxville to Bruxelles-National in December.
ProviderPrice AccuracyTrust Score*
FlightHubPrice Accuracy3 starsTrust Score*1 star
eDreamsPrice Accuracy3 starsTrust Score*3 stars
OvagoPrice Accuracy2 starsTrust Score*2 stars

*The Trust Score is based on feedback from users after their booking experience. It measures overall satisfaction, helping us identify issues like hidden fees, problems during the ticketing process, and the quality of customer service. This score is our best indicator of the provider's quality and reliability.

  • Most accurate provider: When it comes to deals on Knoxville-Brussels Bruxelles-National Airport flights, users find the pricing of eDreams to be most consistent on Cheapflights vs. eDreams Users can find the same prices on Knoxville-Brussels Bruxelles-National Airport flight deals on Cheapflights vs. eDreams >95% of the time. Price accuracy is based on data collected from Knoxville-Brussels Bruxelles-National Airport flight searches over the past month and is updated monthly.
  • Most trusted provider: When it comes to deals on Knoxville-Brussels Bruxelles-National Airport flights, Cheapflights users trust eDreams the most. eDreams has received a user feedback score of 3 out of 3 stars (3 being the best), meaning they have been trusted the most by Cheapflights users looking for Knoxville-Brussels Bruxelles-National Airport flight deals. Provider user feedback score is based on Cheapflights searches over the past month and is updated monthly.

Best time to book a flight from Knoxville to Bruxelles-National

Have a flexible travel schedule? Discover the best time to fly to Bruxelles-National from Knoxville with our price prediction graph.
Estimated round-trip price
Rates are based on past data. Find the cheapest month and day to book your flight based on your travel requirements, then search for cheap deals.

Cheapflights Insights

Everything you need to know about your flight from Knoxville to Brussels Bruxelles-National Airport

What is the cheapest time of day to fly from TYS to BRU?

Find hourly flight availability from Knoxville to Bruxelles-National. Discover flight options and departure times throughout the day, allowing you to choose a departure time that suits your schedule. Data last updated December 26, 2025.

A simple way to save on the total cost of your ticket is to fly from Knoxville to Brussels Bruxelles-National Airport in the afternoon. If you’re flexible enough to do this you can expect to save up to 38% on your trip compared to booking a flight in the evening.

Reviews of airlines servicing Bruxelles-National

Get insights into the airlines that provide service to Bruxelles-National. Read reviews, discover amenities, and learn about the overall travel experience offered by airlines. Use this information to make informed decisions when choosing an airline for your flight to Bruxelles-National. Reviews last updated December 26, 2025.
Read through reviews of airlines operating flights from Knoxville to Brussels Bruxelles-National Airport, such as United Airlines. Reviews also offer insight into each airline's entertainment options, comfort, food, crew/service, and boarding process.
United Airlines
7.4
Good
9,115 reviews

Overall

7.4

Comfort

7.3

Crew

8.1

Food

6.6

Boarding

7.7

Entertainment

7.1

Reviews

1 / 20
10.0
Excellent

Michelle,Dec 2025

DEN - MKE

I liked that the plane waited 5 minutes for a family whose incoming plane was late. This was the last flight of the day to MKE. Flight attendants actually checked in throughout the flight. Although, not really friendly. Happy to see screens on seat backs again. This is my first time not flying first class in over 10 years. It was economy plus.
United Airlines
7.4
Good
9,115 reviews
United Airlines
7.4
Good
9,115 reviews

Overall

7.4

Comfort

7.3

Crew

8.1

Food

6.6

Boarding

7.7

Entertainment

7.1

Reviews

1 / 20
10.0
Excellent

Michelle,Dec 2025

DEN - MKE

I liked that the plane waited 5 minutes for a family whose incoming plane was late. This was the last flight of the day to MKE. Flight attendants actually checked in throughout the flight. Although, not really friendly. Happy to see screens on seat backs again. This is my first time not flying first class in over 10 years. It was economy plus.

Related info for your journey

Find useful and relevant information for your journey from Knoxville to Bruxelles-National. Access travel guides, tips, and recommendations to enhance your travel experience. Get information about local attractions, weather, transportation options, and more.

  • What airport do you fly from for flights from Knoxville to Brussels Bruxelles-National?

    Located just 11.3 mi from the city center, Knoxville McGhee Tyson is the airport most travelers will use when flying to Brussels Bruxelles-National from Knoxville. Booking flights from McGhee Tyson (TYS) to Brussels Bruxelles-National should be relatively easy as there are 0 daily outbound flights to Brussels Bruxelles-National from 1 airline.

  • How long is the flight from Knoxville to Brussels Bruxelles-National Airport?

    United Airlines and Lufthansa can get you from Knoxville to Brussels Bruxelles-National Airport in just under 10h 50m. Your travel time can differ by up to 12h 45m. There are 4289 mi between Knoxville and Brussels Bruxelles-National Airport. This flight may include one or multiple stops.

  • What is the cheapest airline to fly from Knoxville to Brussels Bruxelles-National Airport round-trip?

    Our cheapest airline available from Knoxville to Brussels Bruxelles-National Airport is United Airlines. Our recent data shows that you can find tickets from as low as $603 on this airline.

  • Can I find deals for flights from Knoxville to Bruxelles-National that include hotel bookings?

    Yes. In addition to deals on Knoxville to Bruxelles-National flights, Cheapflights offers vacation packages that include both flights and hotel.

  • How can I find direct flights from Knoxville to Bruxelles-National?

    After entering your origin and destination, apply the non-stop filter on the search result page to find direct flights from Knoxville to Bruxelles-National.

  • Can I find deals for business class flights from Knoxville to Bruxelles-National?

    Yes. Cheapflights offers flight deals from Knoxville to Bruxelles-National by cabin class. In addition to browsing deals, you can also filter by cabin class on the search results page after making a search.

See more FAQs

Traveling to a place near Brussels Bruxelles-National Airport?

Book flights to Brussels Bruxelles-National Airport if you plan to visit one of these locations
Mons
Hasselt
Charleroi
Mechelen
Zaventem

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Alternative routes for Knoxville to Bruxelles-National

See prices for flight routes from nearby airports that may be better suited for you.
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Top airline flying from Knoxville to Bruxelles-National

Discover the top airline that operate flights from Knoxville to Bruxelles-National. Compare their services, reliability, and customer satisfaction ratings to choose the airline that best suits your travel preferences and needs. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated December 26, 2025.
AirlineCheapestAverageFlexibilityOn-time
United AirlinesCheapest$603Average$1,314FlexibilityNo cancel feeOn-time69%

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