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Bruxelles-National

$381+ Cheap flights from Des Moines (DSM) to Bruxelles-National (BRU)

This is the cheapest one-way flight price found by a Cheapflights user in the last 72 hours by searching for a flight departing on 1/25. Fares are subject to change and may not be available on all flights or dates of travel.
DSM — BRU
Jan 11 — Jan 181
Sun 1/11
Sun 1/18
1 adult, Economy
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Cheap flight deals from Des Moines to Bruxelles-National

Cheapest flights from Des Moines to Bruxelles-National
Explore the most affordable flight options available from Des Moines to Bruxelles-National. Find the lowest fares from popular airlines and budget airlines, with prices last updated on December 12, 2025.

This United Airlines deal was found by Cheapflights users on 12/11. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 12/278:00 amDSM - BRU
2 stops21h 35mUnited Airlines
Sun 1/114:55 pmBRU - DSM
2 stops36h 35mUnited Airlines
Deal found 12/11$945
This Ovago deal was found by Cheapflights users on 12/11. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Ovago is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 12/2711:35 amDSM - BRU
1 stop14h 20mLufthansa
Sun 1/1110:10 amBRU - DSM
1 stop14h 37mLufthansa
Deal found 12/11$1,344
This Air Canada deal was found by Cheapflights users on 12/11. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Air Canada is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 12/278:00 amDSM - BRU
3 stops16h 50mMultiple Airlines
Sun 1/1110:00 amBRU - DSM
2 stops31h 55mMultiple Airlines
Deal found 12/11$1,453
This Cheapflightsfares deal was found by Cheapflights users on 12/10. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Cheapflightsfares is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 12/2611:35 amDSM - BRU
1 stop14h 20mLufthansa
Thu 1/16:45 amBRU - DSM
2 stops21h 55mLufthansa
Deal found 12/10$1,455
This United Airlines deal was found by Cheapflights users on 12/10. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 12/268:00 amDSM - BRU
1 stop17h 55mUnited Airlines
Thu 1/110:10 amBRU - DSM
1 stop14h 55mUnited Airlines
Deal found 12/10$1,457
This Air Canada deal was found by Cheapflights users on 12/10. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Air Canada is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 12/268:00 amDSM - BRU
3 stops16h 50mMultiple Airlines
Thu 1/110:00 amBRU - DSM
2 stops31h 50mMultiple Airlines
Deal found 12/10$1,748
This Air Canada deal was found by Cheapflights users on 12/10. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Air Canada is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 12/268:00 amDSM - BRU
3 stops16h 50mAir Canada
Thu 1/17:00 amBRU - DSM
3 stops21h 40mAir Canada
Deal found 12/10$2,050
This Air Canada deal was found by Cheapflights users on 12/11. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Air Canada is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 12/278:00 amDSM - BRU
3 stops16h 50mAir Canada
Sun 1/119:40 amBRU - DSM
3 stops19h 10mAir Canada
Deal found 12/11$2,400

Find flight deals from Des Moines to Bruxelles-National

Discover tips and strategies to find the most affordable flight options for your journey from Des Moines (DSM) to Bruxelles-National (BRU). Learn about various techniques such as flexible date searches, comparing prices across and setting up price alerts. Use these methods to find the cheapest flights available for your travel needs. Data last updated December 12, 2025.

Most accurate provider

eDreams
3 stars

Most trusted provider

eDreams
3 stars

Round-trip from

$427
(Ticket)

One-way from

$381
(Mytrip)
Provider with most accurate pricing for Des Moines-Brussels Bruxelles-National flight deals.
Search Deals
Provider most trusted by Cheapflights users for Des Moines-Brussels Bruxelles-National flights.
Search Deals
From Des Moines to Brussels Bruxelles-National
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One-way flight from Des Moines to Brussels Bruxelles-National
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Cheapflights Fare Finder

 
Customize your flight search to find flights from Des Moines to Bruxelles-National that fit within your specific budget. Explore options based on user searches and filter the results based on your desired price range. Find flights that match your budget for a cost-effective journey. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated December 12, 2025.
Use the filters below to find and compare flights from Des Moines to Brussels Bruxelles-National Airport that are best for you.

Fly from

Des Moines

Fly to

Bruxelles-National

Route

Depart

Return

Price

Des MoinesBrussels

DSM - BRU

DSMBRU

Des Moines

Sat 1/24

7:50 am-7:50 am

2 stops17h 00m

Brussels Bruxelles-National

Sat 1/31

10:00 am-2:33 pm

2 stops35h 33m

$427

Des MoinesBrussels

DSM - BRU

DSMBRU

Des Moines

Mon 1/26

5:30 am-1:15 pm

2 stops24h 45m

Brussels Bruxelles-National

Mon 2/2

10:00 am-2:33 pm

2 stops35h 33m

$484

Des MoinesBrussels

DSM - BRU

DSMBRU

Des Moines

Sun 1/25

5:09 pm-1:15 pm

2 stops37h 06m

Brussels Bruxelles-National

Sun 2/1

10:00 am-9:50 pm

2 stops42h 50m

$484

Des MoinesBrussels

DSM - BRU

DSMBRU

Des Moines

Thu 1/22

1:35 pm-1:15 pm

2 stops16h 40m

Brussels Bruxelles-National

Thu 1/29

10:00 am-2:33 pm

2 stops35h 33m

$484

Des MoinesBrussels

DSM - BRU

DSMBRU

Des Moines

Sun 1/25

4:30 pm-9:35 am

3 stops34h 05m

$381

Des MoinesBrussels

DSM - BRU

DSMBRU

Des Moines

Sat 5/2

6:45 pm-9:00 am

1 stop31h 15m

$387

Des MoinesBrussels

DSM - BRU

DSMBRU

Des Moines

Sat 1/24

6:48 pm-7:50 am

2 stops30h 02m

$393

Des MoinesBrussels

DSM - BRU

DSMBRU

Des Moines

Sun 1/25

6:48 pm-7:50 am

2 stops30h 02m

$394

Des MoinesBrussels

DSM - BRU

DSMBRU

Des Moines

Sun 1/25

3:35 pm-8:55 am

1 stop10h 20m

$395

Des MoinesBrussels

DSM - BRU

DSMBRU

Des Moines

Sat 1/24

7:50 am-8:55 am

1 stop18h 05m

$399

Flights are sorted by cheapest round-trip flights first.

Deals found on 12/11

Showing 1-10 of 11 results
1
2

Compare providers for flights from Des Moines to Bruxelles-National

Provider information is updated monthly. Please note that these providers often have deals for this flight, but the availability may vary on a day-by-day basis on Cheapflights.
Use the table below to compare price accuracy, trust ratings, and cancellation policies for each provider offering flight deals from Des Moines to Bruxelles-National in December.
ProviderPrice AccuracyTrust Score*
eDreamsPrice Accuracy3 starsTrust Score*3 stars
OvagoPrice Accuracy2 starsTrust Score*2 stars
FlightHubPrice Accuracy3 starsTrust Score*1 star

*The Trust Score is based on feedback from users after their booking experience. It measures overall satisfaction, helping us identify issues like hidden fees, problems during the ticketing process, and the quality of customer service. This score is our best indicator of the provider's quality and reliability.

  • Most accurate provider: When it comes to deals on Des Moines-Brussels Bruxelles-National Airport flights, users find the pricing of eDreams to be most consistent on Cheapflights vs. eDreams Users can find the same prices on Des Moines-Brussels Bruxelles-National Airport flight deals on Cheapflights vs. eDreams >95% of the time. Price accuracy is based on data collected from Des Moines-Brussels Bruxelles-National Airport flight searches over the past month and is updated monthly.
  • Most trusted provider: When it comes to deals on Des Moines-Brussels Bruxelles-National Airport flights, Cheapflights users trust eDreams the most. eDreams has received a user feedback score of 3 out of 3 stars (3 being the best), meaning they have been trusted the most by Cheapflights users looking for Des Moines-Brussels Bruxelles-National Airport flight deals. Provider user feedback score is based on Cheapflights searches over the past month and is updated monthly.

Best time to book a flight from Des Moines to Bruxelles-National

Have a flexible travel schedule? Discover the best time to fly to Bruxelles-National from Des Moines with our price prediction graph.
Estimated round-trip price
Rates are based on past data. Find the cheapest month and day to book your flight based on your travel requirements, then search for cheap deals.

Reviews of airlines servicing Bruxelles-National

Get insights into the airlines that provide service to Bruxelles-National. Read reviews, discover amenities, and learn about the overall travel experience offered by airlines. Use this information to make informed decisions when choosing an airline for your flight to Bruxelles-National. Reviews last updated December 12, 2025.
Get a feel of what it's like to fly with United Airlines from Des Moines to Brussels Bruxelles-National Airport by reading reviews from past customers. You can also see how each airline compares in terms of entertainment options, comfort, food, crew/service, and boarding process.
United Airlines
7.4
Good
9,095 reviews

Entertainment

7.1

Food

6.6

Boarding

7.7

Comfort

7.3

Crew

8.1

Overall

7.4

Reviews

1 / 20
10.0
Excellent

Sunderesh,Dec 2025

AUS - EWR

Smooth flight from Austin to Newark. The crew was friendly.
United Airlines
7.4
Good
9,095 reviews
United Airlines
7.4
Good
9,095 reviews

Entertainment

7.1

Food

6.6

Boarding

7.7

Comfort

7.3

Crew

8.1

Overall

7.4

Reviews

1 / 20
10.0
Excellent

Sunderesh,Dec 2025

AUS - EWR

Smooth flight from Austin to Newark. The crew was friendly.

Related info for your journey

Find useful and relevant information for your journey from Des Moines to Bruxelles-National. Access travel guides, tips, and recommendations to enhance your travel experience. Get information about local attractions, weather, transportation options, and more.

  • What airport do you fly from for flights from Des Moines to Brussels Bruxelles-National?

    Most people fly from Des Moines (DSM) if they book a flight from Des Moines to Brussels Bruxelles-National. On average, Des Moines has 0 outbound flights to Brussels Bruxelles-National per day from 1 airline. Des Moines is conveniently located just 3.6 mi from Des Moines’s city center.

  • How long is the flight from Des Moines to Brussels Bruxelles-National Airport?

    Air Canada and United Airlines can get you from Des Moines to Brussels Bruxelles-National Airport in just under 17h. Your travel time can differ by up to 7h 45m. Airlines will cover a distance of 4377 mi. When browsing for deals, the options you’ll see will be for both nonstop flights and flights with stops.

  • What is the cheapest airline to fly from Des Moines to Brussels Bruxelles-National Airport round-trip?

    Currently priced at $757, United Airlines will fly you from Des Moines to Brussels Bruxelles-National Airport and back. In addition to United Airlines, many other airlines offer competitively priced options for your trip.

  • Can I find deals for flights from Des Moines to Bruxelles-National that include hotel bookings?

    Yes. In addition to deals on Des Moines to Bruxelles-National flights, Cheapflights offers vacation packages that include both flights and hotel.

  • How can I find direct flights from Des Moines to Bruxelles-National?

    After entering your origin and destination, apply the non-stop filter on the search result page to find direct flights from Des Moines to Bruxelles-National.

  • Can I find deals for business class flights from Des Moines to Bruxelles-National?

    Yes. Cheapflights offers flight deals from Des Moines to Bruxelles-National by cabin class. In addition to browsing deals, you can also filter by cabin class on the search results page after making a search.

See more FAQs

Traveling to a place near Brussels Bruxelles-National Airport?

Book flights to Brussels Bruxelles-National Airport if you plan to visit one of these locations
Mons
Hasselt
Charleroi
Mechelen
Zaventem

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Alternative routes for Des Moines to Bruxelles-National

See prices for flight routes from nearby airports that may be better suited for you.
Omaha to Bruxelles-National flights

Top airline flying from Des Moines to Bruxelles-National

Discover the top airline that operate flights from Des Moines to Bruxelles-National. Compare their services, reliability, and customer satisfaction ratings to choose the airline that best suits your travel preferences and needs. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated December 12, 2025.
AirlineCheapestAverageFlexibilityOn-time
United AirlinesCheapest$757Average$1,444FlexibilityNo cancel feeOn-time69%

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