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Bruxelles-National

$240+ Cheap flights from Des Moines (DSM) to Bruxelles-National (BRU)

This is the cheapest one-way flight price found by a Cheapflights user in the last 72 hours by searching for a flight departing on 4/26. Fares are subject to change and may not be available on all flights or dates of travel.
DSM — BRU
Feb 26 — Mar 51
Thu 2/26
Thu 3/5
1 adult, Economy
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Cheap flight deals from Des Moines to Bruxelles-National

Cheapest flights from Des Moines to Bruxelles-National
Explore the most affordable flight options available from Des Moines to Bruxelles-National. Find the lowest fares from popular airlines and budget airlines, with prices last updated on January 27, 2026.

This Flighttix deal was found by Cheapflights users on 1/25. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Flighttix is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 3/103:28 pm
DSM
-
BRU
2 stops34h 22m
Multiple Airlines
Tue 3/1710:10 am
BRU
-
DSM
1 stop17h 30m
Multiple Airlines
Deal found 1/25$483
This United Airlines deal was found by Cheapflights users on 1/24. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 3/98:00 am
DSM
-
BRU
2 stops23h 15m
United Airlines
Mon 3/1610:00 am
BRU
-
DSM
2 stops34h 22m
United Airlines
Deal found 1/24$485
This Flysmarter deal was found by Cheapflights users on 1/25. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Flysmarter is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 3/105:20 pm
DSM
-
BRU
1 stop32h 40m
KLM
Tue 3/1710:00 am
BRU
-
DSM
1 stop18h 38m
KLM
Deal found 1/25$499
This United Airlines deal was found by Cheapflights users on 1/26. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 3/108:00 am
DSM
-
BRU
2 stops23h 15m
United Airlines
Tue 3/1710:10 am
BRU
-
DSM
1 stop17h 30m
United Airlines
Deal found 1/26$505
This KLM deal was found by Cheapflights users on 1/24. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure KLM is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 3/95:35 am
DSM
-
BRU
1 stop20h 25m
KLM
Mon 3/1610:00 am
BRU
-
DSM
1 stop18h 38m
KLM
Deal found 1/24$508
This United Airlines deal was found by Cheapflights users on 1/25. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 2/255:30 am
DSM
-
BRU
2 stops42h 45m
United Airlines
Sun 3/110:00 am
BRU
-
DSM
3 stops59h 27m
United Airlines
Deal found 1/25$509
This Air Canada deal was found by Cheapflights users on 1/26. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Air Canada is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 3/102:04 pm
DSM
-
BRU
3 stops17h 11m
Air Canada
Tue 3/177:00 am
BRU
-
DSM
3 stops20h 40m
Air Canada
Deal found 1/26$520

Find flight deals from Des Moines to Bruxelles-National

Discover tips and strategies to find the most affordable flight options for your journey from Des Moines (DSM) to Bruxelles-National (BRU). Learn about various techniques such as flexible date searches, comparing prices across and setting up price alerts. Use these methods to find the cheapest flights available for your travel needs. Data last updated January 27, 2026.

Most accurate provider

FlightHub
3 stars

Most trusted provider

FlightHub
3 stars

Round-trip from

$483
(Flighttix)

One-way from

$240
(oojo)
Provider with most accurate pricing for Des Moines-Brussels Bruxelles-National flight deals.
Search Deals
Provider most trusted by Cheapflights users for Des Moines-Brussels Bruxelles-National flights.
Search Deals
From Des Moines to Brussels Bruxelles-National
Search Deals
One-way flight from Des Moines to Brussels Bruxelles-National
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Cheapflights Fare Finder

 
Customize your flight search to find flights from Des Moines to Bruxelles-National that fit within your specific budget. Explore options based on user searches and filter the results based on your desired price range. Find flights that match your budget for a cost-effective journey. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated January 27, 2026.
Use the filters below to find and compare flights from Des Moines to Brussels Bruxelles-National Airport that are best for you.

Fly from

Des Moines

Fly to

Bruxelles-National

Route

Depart

Return

Price

Des MoinesBrussels

DSM - BRU

DSMBRU

Des Moines

Tue 3/10

5:20 pm-8:00 am

1 stop32h 40m

Brussels Bruxelles-National

Tue 3/17

10:00 am-10:38 pm

1 stop18h 38m

$505

Des MoinesBrussels

DSM - BRU

DSMBRU

Des Moines

Mon 3/9

8:00 am-1:15 pm

2 stops23h 15m

Brussels Bruxelles-National

Mon 3/16

10:10 am-2:22 pm

1 stop34h 12m

$505

Des MoinesBrussels

DSM - BRU

DSMBRU

Des Moines

Tue 3/10

5:30 am-1:15 pm

2 stops25h 45m

Brussels Bruxelles-National

Tue 3/17

10:10 am-9:40 pm

1 stop17h 30m

$505

Des MoinesBrussels

DSM - BRU

DSMBRU

Des Moines

Mon 3/9

5:35 am-8:00 am

1 stop20h 25m

Brussels Bruxelles-National

Mon 3/16

10:00 am-10:38 pm

1 stop18h 38m

$508

Des MoinesBrussels

DSM - BRU

DSMBRU

Des Moines

Wed 2/25

5:30 am-7:15 am

2 stops42h 45m

Brussels Bruxelles-National

Sun 3/1

10:00 am-2:27 pm

3 stops59h 27m

$509

Des MoinesBrussels

DSM - BRU

DSMBRU

Des Moines

Sun 4/26

5:00 pm-8:00 pm

2 stops20h 00m

$240

Des MoinesBrussels

DSM - BRU

DSMBRU

Des Moines

Sun 4/26

7:05 pm-8:00 pm

2 stops17h 55m

$247

Des MoinesBrussels

DSM - BRU

DSMBRU

Des Moines

Sat 5/2

3:20 pm-7:50 am

2 stops33h 30m

$247

Des MoinesBrussels

DSM - BRU

DSMBRU

Des Moines

Sat 5/2

8:01 pm-2:10 pm

2 stops35h 09m

$251

Des MoinesBrussels

DSM - BRU

DSMBRU

Des Moines

Sat 5/2

6:45 pm-9:00 am

1 stop31h 15m

$262

Flights are sorted by cheapest round-trip flights first.

Deals found on 1/26

Showing 1-10 of 13 results
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Compare providers for flights from Des Moines to Bruxelles-National

Provider information is updated monthly. Please note that these providers often have deals for this flight, but the availability may vary on a day-by-day basis on Cheapflights.
Use the table below to compare price accuracy, trust ratings, and cancellation policies for each provider offering flight deals from Des Moines to Bruxelles-National in January.
ProviderPrice AccuracyTrust Score*
OvagoPrice Accuracy2 starsTrust Score*3 stars
FlightHubPrice Accuracy3 starsTrust Score*3 stars

*The Trust Score is based on feedback from users after their booking experience. It measures overall satisfaction, helping us identify issues like hidden fees, problems during the ticketing process, and the quality of customer service. This score is our best indicator of the provider's quality and reliability.

  • Most accurate provider: When it comes to deals on Des Moines-Brussels Bruxelles-National Airport flights, users find the pricing of FlightHub to be most consistent on Cheapflights vs. FlightHub Users can find the same prices on Des Moines-Brussels Bruxelles-National Airport flight deals on Cheapflights vs. FlightHub >95% of the time. Price accuracy is based on data collected from Des Moines-Brussels Bruxelles-National Airport flight searches over the past month and is updated monthly.
  • Most trusted provider: When it comes to deals on Des Moines-Brussels Bruxelles-National Airport flights, Cheapflights users trust FlightHub the most. FlightHub has received a user feedback score of 3 out of 3 stars (3 being the best), meaning they have been trusted the most by Cheapflights users looking for Des Moines-Brussels Bruxelles-National Airport flight deals. Provider user feedback score is based on Cheapflights searches over the past month and is updated monthly.

Best time to book a flight from Des Moines to Bruxelles-National

Have a flexible travel schedule? Discover the best time to fly to Bruxelles-National from Des Moines with our price prediction graph.
Estimated round-trip price
Rates are based on past data. Find the cheapest month and day to book your flight based on your travel requirements, then search for cheap deals.

Reviews of airlines servicing Bruxelles-National

Get insights into the airlines that provide service to Bruxelles-National. Read reviews, discover amenities, and learn about the overall travel experience offered by airlines. Use this information to make informed decisions when choosing an airline for your flight to Bruxelles-National. Reviews last updated January 27, 2026.
Get a feel of what it's like to fly with United Airlines from Des Moines to Brussels Bruxelles-National Airport by reading reviews from past customers. You can also see how each airline compares in terms of entertainment options, comfort, food, crew/service, and boarding process.
United Airlines
7.4
Good
9,205 reviews

Crew

8.1

Comfort

7.3

Food

6.6

Overall

7.4

Boarding

7.7

Entertainment

7.1

Reviews

1 / 20
10.0
Excellent

Dane,Jan 2026

TYS - IAD

It was a short flight, so no time for amenities. Just glad everything was quick and easy from boarding to arriving at my destination with my family
United Airlines
7.4
Good
9,205 reviews
United Airlines
7.4
Good
9,205 reviews

Crew

8.1

Comfort

7.3

Food

6.6

Overall

7.4

Boarding

7.7

Entertainment

7.1

Reviews

1 / 20
10.0
Excellent

Dane,Jan 2026

TYS - IAD

It was a short flight, so no time for amenities. Just glad everything was quick and easy from boarding to arriving at my destination with my family

Related info for your journey

Find useful and relevant information for your journey from Des Moines to Bruxelles-National. Access travel guides, tips, and recommendations to enhance your travel experience. Get information about local attractions, weather, transportation options, and more.

  • What airport do you fly from for flights from Des Moines to Brussels Bruxelles-National?

    Most people fly from Des Moines (DSM) if they book a flight from Des Moines to Brussels Bruxelles-National. On average, Des Moines has 0 outbound flights to Brussels Bruxelles-National per day from 1 airline. Des Moines is conveniently located just 3.6 mi from Des Moines’s city center.

  • How long is the flight from Des Moines to Brussels Bruxelles-National Airport?

    KLM and United Airlines can get you from Des Moines to Brussels Bruxelles-National Airport in just under 23h 15m. Your travel time can differ by up to 9h 25m. Airlines will cover a distance of 4377 mi. When browsing for deals, the options you’ll see will be for both nonstop flights and flights with stops.

  • What is the cheapest airline to fly from Des Moines to Brussels Bruxelles-National Airport round-trip?

    Currently priced at $707, United Airlines will fly you from Des Moines to Brussels Bruxelles-National Airport and back. In addition to United Airlines, many other airlines offer competitively priced options for your trip.

  • Can I find deals for flights from Des Moines to Bruxelles-National that include hotel bookings?

    Yes. In addition to deals on Des Moines to Bruxelles-National flights, Cheapflights offers vacation packages that include both flights and hotel.

  • How can I find direct flights from Des Moines to Bruxelles-National?

    After entering your origin and destination, apply the non-stop filter on the search result page to find direct flights from Des Moines to Bruxelles-National.

  • Can I find deals for business class flights from Des Moines to Bruxelles-National?

    Yes. Cheapflights offers flight deals from Des Moines to Bruxelles-National by cabin class. In addition to browsing deals, you can also filter by cabin class on the search results page after making a search.

See more FAQs

Traveling to a place near Brussels Bruxelles-National Airport?

Book flights to Brussels Bruxelles-National Airport if you plan to visit one of these locations
Mons
Hasselt
Charleroi
Mechelen
Zaventem

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Alternative routes for Des Moines to Bruxelles-National

See prices for flight routes from nearby airports that may be better suited for you.
Omaha to Bruxelles-National flights

Top airline flying from Des Moines to Bruxelles-National

Discover the top airline that operate flights from Des Moines to Bruxelles-National. Compare their services, reliability, and customer satisfaction ratings to choose the airline that best suits your travel preferences and needs. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated January 27, 2026.
AirlineCheapestAverageFlexibilityOn-time
United AirlinesCheapest$707Average$1,444FlexibilityNo cancel feeOn-time69%

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