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Bruxelles-National

$453+ Cheap flights from Des Moines (DSM) to Bruxelles-National (BRU)

This is the cheapest one-way flight price found by a Cheapflights user in the last 72 hours by searching for a flight departing on 10/26. Fares are subject to change and may not be available on all flights or dates of travel.
DSM — BRU
oct. 11 — oct. 181
sáb. 10/11
sáb. 10/18
1 adult, Economy
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Cheap flight deals from Des Moines to Bruxelles-National

Discover tips and strategies to find the most affordable flight options for your journey from Des Moines (DSM) to Bruxelles-National (BRU). Learn about various techniques such as flexible date searches, comparing prices across and setting up price alerts. Use these methods to find the cheapest flights available for your travel needs. Data last updated septiembre 11, 2025.

Round-trip from

$586
(FlightHub)

One-way from

$453
(Delta)
From Des Moines to Brussels Bruxelles-National
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One-way flight from Des Moines to Brussels Bruxelles-National
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Find flight deals from Des Moines to Bruxelles-National

Cheapest flights from Des Moines to Bruxelles-National
Explore the most affordable flight options available from Des Moines to Bruxelles-National. Find the lowest fares from popular airlines and budget airlines, with prices last updated on septiembre 11, 2025.

This FlightHub deal was found by Cheapflights users on 9/9. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure FlightHub is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
jue. 10/1610:50 amDSM - BRU
2 stops26h 00mScandinavian Airlines
mar. 10/2810:20 amBRU - DSM
2 stops18h 10mScandinavian Airlines
Deal found 9/9$586
This Rumbo deal was found by Cheapflights users on 9/10. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Rumbo is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
dom. 10/262:13 pmDSM - BRU
2 stops18h 17mScandinavian Airlines
dom. 11/23:10 pmBRU - DSM
2 stops38h 20mScandinavian Airlines
Deal found 9/10$644
This lastminute.com deal was found by Cheapflights users on 9/10. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure lastminute.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
sáb. 10/2510:50 amDSM - BRU
2 stops40h 50mScandinavian Airlines
sáb. 11/13:10 pmBRU - DSM
2 stops38h 20mScandinavian Airlines
Deal found 9/10$646
This Delta deal was found by Cheapflights users on 9/9. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
jue. 10/166:05 amDSM - BRU
2 stops19h 35mDelta
mar. 10/2810:00 amBRU - DSM
2 stops18h 30mDelta
Deal found 9/9$666
This American Airlines deal was found by Cheapflights users on 9/11. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
dom. 10/261:48 pmDSM - BRU
2 stops15h 42mAmerican Airlines
dom. 11/211:20 amBRU - DSM
2 stops20h 01mAmerican Airlines
Deal found 9/11$668
This American Airlines deal was found by Cheapflights users on 9/11. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
vie. 10/241:48 pmDSM - BRU
2 stops14h 37mAmerican Airlines
vie. 10/3111:45 amBRU - DSM
2 stops27h 15mAmerican Airlines
Deal found 9/11$701
This KLM deal was found by Cheapflights users on 9/10. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure KLM is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
dom. 10/262:13 pmDSM - BRU
2 stops13h 57mKLM
dom. 11/28:05 amBRU - DSM
2 stops15h 47mKLM
Deal found 9/10$708

Cheapflights Fare Finder

 
Customize your flight search to find flights from Des Moines to Bruxelles-National that fit within your specific budget. Explore options based on user searches and filter the results based on your desired price range. Find flights that match your budget for a cost-effective journey. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated septiembre 11, 2025.
Use the filters below to find and compare flights from Des Moines to Brussels Bruxelles-National Airport that are best for you.

Fly from

Des Moines

Fly to

Bruxelles-National

Route

Depart

Return

Price

Des MoinesBrussels

DSM - BRU

DSMBRU

Des Moines

jue. 10/16

10:50 am-7:50 pm

2 stops26h 00m

Brussels Bruxelles-National

mar. 10/28

10:20 am-10:30 pm

2 stops18h 10m

$586

Des MoinesBrussels

DSM - BRU

DSMBRU

Des Moines

dom. 10/26

2:13 pm-2:30 pm

2 stops18h 17m

Brussels Bruxelles-National

dom. 11/2

3:10 pm-10:30 pm

2 stops38h 20m

$644

Des MoinesBrussels

DSM - BRU

DSMBRU

Des Moines

sáb. 10/25

10:50 am-10:40 am

2 stops40h 50m

Brussels Bruxelles-National

sáb. 11/1

3:10 pm-11:30 pm

2 stops38h 20m

$646

Des MoinesBrussels

DSM - BRU

DSMBRU

Des Moines

jue. 10/16

5:47 am-8:40 am

1 stop19h 53m

Brussels Bruxelles-National

mar. 10/28

10:00 am-10:30 pm

2 stops18h 30m

$666

Des MoinesBrussels

DSM - BRU

DSMBRU

Des Moines

dom. 10/26

1:48 pm-11:30 am

2 stops15h 42m

Brussels Bruxelles-National

dom. 11/2

11:20 am-12:21 am

2 stops20h 01m

$668

Des MoinesBrussels

DSM - BRU

DSMBRU

Des Moines

vie. 10/24

1:48 pm-11:25 am

2 stops14h 37m

Brussels Bruxelles-National

vie. 10/31

11:45 am-9:00 am

2 stops27h 15m

$701

Des MoinesBrussels

DSM - BRU

DSMBRU

Des Moines

dom. 10/26

2:13 pm-10:10 am

2 stops13h 57m

Brussels Bruxelles-National

dom. 11/2

8:05 am-4:52 pm

2 stops15h 47m

$708

Des MoinesBrussels

DSM - BRU

DSMBRU

Des Moines

dom. 10/26

6:05 am-8:00 am

2 stops19h 55m

$453

Des MoinesBrussels

DSM - BRU

DSMBRU

Des Moines

dom. 10/26

11:26 am-7:55 am

1 stop14h 29m

$568

Des MoinesBrussels

DSM - BRU

DSMBRU

Des Moines

dom. 10/26

1:05 pm-7:55 am

1 stop12h 50m

$668

Flights are sorted by cheapest round-trip flights first.

Deals found on 9/11

Showing 1-10 of 11 results
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Best time to book a flight from Des Moines to Bruxelles-National

Have a flexible travel schedule? Discover the best time to fly to Bruxelles-National from Des Moines with our price prediction graph.
Estimated round-trip price
Rates are based on past data. Find the cheapest month and day to book your flight based on your travel requirements, then search for cheap deals.

Reviews of airlines servicing Bruxelles-National

Get insights into the airlines that provide service to Bruxelles-National. Read reviews, discover amenities, and learn about the overall travel experience offered by airlines. Use this information to make informed decisions when choosing an airline for your flight to Bruxelles-National. Reviews last updated septiembre 11, 2025.
Get a feel of what it's like to fly with United Airlines from Des Moines to Brussels Bruxelles-National Airport by reading reviews from past customers. You can also see how each airline compares in terms of entertainment options, comfort, food, crew/service, and boarding process.
United Airlines
7.4
Good
8,937 reviews

Comfort

7.3

Entertainment

7.1

Overall

7.4

Food

6.6

Crew

8.1

Boarding

7.7

Reviews

1 / 20
4.0
Okay

Thomas,Mar 2025

SFO - TPE

When I asked for an extra snack, I got an unhappy look from the stewardess. Geez, does one extra snack really affect the bottom line??
United Airlines
7.4
Good
8,937 reviews
United Airlines
7.4
Good
8,937 reviews

Comfort

7.3

Entertainment

7.1

Overall

7.4

Food

6.6

Crew

8.1

Boarding

7.7

Reviews

1 / 20
4.0
Okay

Thomas,Mar 2025

SFO - TPE

When I asked for an extra snack, I got an unhappy look from the stewardess. Geez, does one extra snack really affect the bottom line??

Related info for your journey

Find useful and relevant information for your journey from Des Moines to Bruxelles-National. Access travel guides, tips, and recommendations to enhance your travel experience. Get information about local attractions, weather, transportation options, and more.

  • What airport do you fly from for flights from Des Moines to Brussels Bruxelles-National?

    Most people fly from Des Moines (DSM) if they book a flight from Des Moines to Brussels Bruxelles-National. On average, Des Moines has 0 outbound flights to Brussels Bruxelles-National per day from 1 airline. Des Moines is conveniently located just 3.6 mi from Des Moines’s city center.

  • How long is the flight from Des Moines to Brussels Bruxelles-National Airport?

    Scandinavian Airlines and Delta can get you from Des Moines to Brussels Bruxelles-National Airport in just under 19h 53m. Your travel time can differ by up to 6h 07m. Airlines will cover a distance of 4377 mi. When browsing for deals, the options you’ll see will be for both nonstop flights and flights with stops.

  • What is the cheapest airline to fly from Des Moines to Brussels Bruxelles-National Airport round-trip?

    Currently priced at $705, United Airlines will fly you from Des Moines to Brussels Bruxelles-National Airport and back. In addition to United Airlines, many other airlines offer competitively priced options for your trip.

  • What are the cheapest airlines to fly from Des Moines to Brussels Bruxelles-National Airport one-way?

    $453 is the cheapest one-way deal found within the past few days, from Delta. You may also be able to find cheap deals on United Airlines and Lufthansa, with prices starting from $568 and $668, respectively.

  • Can I find deals for flights from Des Moines to Bruxelles-National that include hotel bookings?

    Yes. In addition to deals on Des Moines to Bruxelles-National flights, Cheapflights offers vacation packages that include both flights and hotel.

  • How can I find direct flights from Des Moines to Bruxelles-National?

    After entering your origin and destination, apply the non-stop filter on the search result page to find direct flights from Des Moines to Bruxelles-National.

  • Can I find deals for business class flights from Des Moines to Bruxelles-National?

    Yes. Cheapflights offers flight deals from Des Moines to Bruxelles-National by cabin class. In addition to browsing deals, you can also filter by cabin class on the search results page after making a search.

  • What is the cheapest month to book a flight from Des Moines to Brussels Bruxelles-National Airport?

    Currently, November is the cheapest month in which you can book a flight from Des Moines to Brussels Bruxelles-National Airport (average of $614). Flying from Des Moines to Brussels Bruxelles-National Airport in June is currently the most expensive (average of $1,077). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.

See more FAQs

Traveling to a place near Brussels Bruxelles-National Airport?

Book flights to Brussels Bruxelles-National Airport if you plan to visit one of these locations
Charleroi
Mons
Mechelen
Zaventem

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Alternative routes for Des Moines to Bruxelles-National

See prices for flight routes from nearby airports that may be better suited for you.
Omaha to Bruxelles-National flights

Top airline flying from Des Moines to Bruxelles-National

Discover the top airline that operate flights from Des Moines to Bruxelles-National. Compare their services, reliability, and customer satisfaction ratings to choose the airline that best suits your travel preferences and needs. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated septiembre 11, 2025.
AirlineCheapestAverageFlexibilityOn-time
United AirlinesCheapest$705Average$1,100FlexibilityNo cancel feeOn-time69%

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