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$212+ Cheap flights from Sioux Falls (FSD) to Missouri

This is the cheapest round-trip flight price found by a Cheapflights user in the last 72 hours by searching for a flight departing on 11/9. Fares are subject to change and may not be available on all flights or dates of travel.
FSD — STL
Nov 15 — Nov 221
Sat 11/15
Sat 11/22
1 adult, Economy
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Cheap flight deals from Sioux Falls to Missouri

Keep the following information in mind while searching for Sioux Falls to Missouri flight deals. Data was last updated October 16, 2025.

Most accurate provider

FlightHub
3 stars

Most trusted provider

FlightHub
3 stars

Round-trip from

$212
(Kiwi.com)

Popular in

December

Cheapest in

April

Average price

$377
Provider with most accurate pricing for Sioux Falls Joe Foss Field-Lambert-St Louis flight deals.
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Provider most trusted by Cheapflights users for Sioux Falls Joe Foss Field-Lambert-St Louis flights.
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From Sioux Falls Joe Foss Field to Missouri
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Highest demand for flights based on searches. 10% potential increase in price ($39 potential increase over avg. RT price).
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Cheapest flight prices on average. 2% potential price decrease ($11 potential savings vs. average RT price).
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Average for round-trip flights in October 2025
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Find flight deals from Sioux Falls to Missouri

Cheapest flights from Sioux Falls to Missouri
Explore the most affordable flight options available from Sioux Falls to Missouri. Find the lowest fares from popular airlines and budget airlines, with prices last updated on October 16, 2025.

This Kiwi.com deal was found by Cheapflights users on 10/15. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 11/92:18 pmFSD - STL
1 stop18h 49mFrontier
Wed 11/127:45 pmSTL - FSD
1 stop17h 43mFrontier
Deal found 10/15$212
This United Airlines deal was found by Cheapflights users on 10/15. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 11/88:00 amFSD - STL
1 stop4h 28mUnited Airlines
Wed 11/124:55 pmSTL - FSD
1 stop6h 49mUnited Airlines
Deal found 10/15$229
This American Airlines deal was found by Cheapflights users on 10/16. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 10/311:32 pmFSD - STL
1 stop4h 50mAmerican Airlines
Tue 11/41:20 pmSTL - FSD
1 stop7h 50mAmerican Airlines
Deal found 10/16$234
This American Airlines deal was found by Cheapflights users on 10/15. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 11/16:00 amFSD - MCI
1 stop7h 00mAmerican Airlines
Wed 11/55:15 amMCI - FSD
1 stop7h 08mAmerican Airlines
Deal found 10/15$234
This Delta deal was found by Cheapflights users on 10/15. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 10/305:20 amFSD - STL
1 stop3h 31mDelta
Mon 11/34:45 pmSTL - FSD
1 stop6h 12mDelta
Deal found 10/15$239
This American Airlines deal was found by Cheapflights users on 10/15. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 11/11:27 pmFSD - MCI
1 stop7h 42mAmerican Airlines
Tue 11/46:05 amMCI - FSD
1 stop4h 23mAmerican Airlines
Deal found 10/15$239
This Kiwi.com deal was found by Cheapflights users on 10/15. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 11/92:18 pmFSD - STL
1 stop18h 49mMultiple Airlines
Wed 11/127:45 pmSTL - FSD
2 stops38h 01mMultiple Airlines
Deal found 10/15$257
This United Airlines deal was found by Cheapflights users on 10/15. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 10/308:47 amFSD - SGF
1 stop7h 35mUnited Airlines
Mon 11/33:20 pmSGF - FSD
1 stop6h 26mUnited Airlines
Deal found 10/15$257
This American Airlines deal was found by Cheapflights users on 10/16. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 11/211:16 pmFSD - STL
1 stop6h 14mAmerican Airlines
Fri 11/288:40 amSTL - FSD
1 stop4h 33mAmerican Airlines
Deal found 10/16$259
This United Airlines deal was found by Cheapflights users on 10/16. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 10/313:15 pmFSD - SGF
1 stop6h 58mUnited Airlines
Tue 11/48:00 amSGF - FSD
1 stop6h 40mUnited Airlines
Deal found 10/16$264
This Kiwi.com deal was found by Cheapflights users on 10/16. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 10/312:32 pmFSD - STL
1 stop18h 35mMultiple Airlines
Tue 11/47:45 pmSTL - FSD
2 stops39h 04mMultiple Airlines
Deal found 10/16$267
This United Airlines deal was found by Cheapflights users on 10/15. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 10/245:14 pmFSD - STL
1 stop6h 44mUnited Airlines
Sun 10/265:24 pmSTL - FSD
1 stop4h 22mUnited Airlines
Deal found 10/15$269

Cheapflights Fare Finder

 
Customize your flight search to find flights from Sioux Falls to Missouri that fit within your specific budget. Explore options based on user searches and filter the results based on your desired price range. Find flights that match your budget for a cost-effective journey. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated October 16, 2025.
Use the filters below to find and compare flights from Sioux Falls to Missouri that are best for you.

Fly from

Sioux Falls

Fly to

Missouri

Route

Depart

Return

Price

Sioux FallsSt. Louis

FSD - STL

FSDSTL

Sioux Falls Joe Foss Field

Sun 11/9

2:18 pm-9:07 am

1 stop18h 49m

Lambert-St Louis

Wed 11/12

7:45 pm-1:28 pm

1 stop17h 43m

$212

Sioux FallsSt. Louis

FSD - STL

FSDSTL

Sioux Falls Joe Foss Field

Sat 11/8

6:30 am-12:37 pm

1 stop6h 07m

Lambert-St Louis

Wed 11/12

5:40 pm-10:27 pm

1 stop4h 47m

$229

Sioux FallsSt. Louis

FSD - STL

FSDSTL

Sioux Falls Joe Foss Field

Sat 11/15

5:14 pm-9:54 pm

1 stop4h 40m

Lambert-St Louis

Wed 11/19

1:35 pm-8:23 pm

1 stop6h 48m

$229

Sioux FallsSt. Louis

FSD - STL

FSDSTL

Sioux Falls Joe Foss Field

Fri 12/5

5:27 pm-10:47 pm

1 stop5h 20m

Lambert-St Louis

Mon 12/8

1:20 pm-9:04 pm

1 stop7h 44m

$229

Sioux FallsSt. Louis

FSD - STL

FSDSTL

Sioux Falls Joe Foss Field

Sat 11/8

8:00 am-12:28 pm

1 stop4h 28m

Lambert-St Louis

Wed 11/12

4:55 pm-11:44 pm

1 stop6h 49m

$229

Sioux FallsSt. Louis

FSD - STL

FSDSTL

Sioux Falls Joe Foss Field

Sat 11/15

5:14 pm-9:54 pm

1 stop4h 40m

Lambert-St Louis

Tue 11/18

5:24 pm-9:46 pm

1 stop4h 22m

$229

Sioux FallsSt. Louis

FSD - STL

FSDSTL

Sioux Falls Joe Foss Field

Fri 10/31

1:32 pm-6:22 pm

1 stop4h 50m

Lambert-St Louis

Tue 11/4

1:20 pm-9:10 pm

1 stop7h 50m

$234

Sioux FallsKansas City

FSD - MCI

FSDMCI

Sioux Falls Joe Foss Field

Sat 11/1

6:00 am-1:00 pm

1 stop7h 00m

Kansas City

Wed 11/5

5:15 am-12:23 pm

1 stop7h 08m

$234

Sioux FallsSt. Louis

FSD - STL

FSDSTL

Sioux Falls Joe Foss Field

Thu 10/30

5:20 am-8:51 am

1 stop3h 31m

Lambert-St Louis

Mon 11/3

4:45 pm-10:57 pm

1 stop6h 12m

$239

Sioux FallsKansas City

FSD - MCI

FSDMCI

Sioux Falls Joe Foss Field

Sat 11/1

1:27 pm-9:09 pm

1 stop7h 42m

Kansas City

Tue 11/4

6:05 am-10:28 am

1 stop4h 23m

$239

Flights are sorted by cheapest round-trip flights first.

Deals found on 10/15

Showing 1-10 of 32 results
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Best time to book a flight from Sioux Falls to Missouri

Have a flexible travel schedule? Discover the best time to fly to Missouri from Sioux Falls with our price prediction graph.
Estimated round-trip price
Rates are based on past data. Find the cheapest month and day to book your flight based on your travel requirements, then search for cheap deals.

Cheapflights Insights

Everything you need to know about your flight from Sioux Falls to Missouri

What is the cheapest month to book a flight from Sioux Falls to Missouri?

Currently, February is the cheapest month in which you can book a flight from Sioux Falls to Missouri (average of $203). Flying from Sioux Falls to Missouri in July is currently the most expensive (average of $313). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.

What is the cheapest time of day to fly from FSD to MO?

Find hourly flight availability from Sioux Falls to Missouri. Discover flight options and departure times throughout the day, allowing you to choose a departure time that suits your schedule. Data last updated October 16, 2025.

It’s optimal to fly from Sioux Falls to Missouri in the evening. By choosing this option you can save up to 39% on the cost of your flight, compared to a flight in the morning.

How much does it cost to fly round-trip from Sioux Falls to Missouri?

Reviews of airlines servicing Missouri

Get insights into the airlines that provide service to Missouri. Read reviews, discover amenities, and learn about the overall travel experience offered by airlines. Use this information to make informed decisions when choosing an airline for your flight to Missouri. Reviews last updated October 16, 2025.
Read reviews from past customers who have flown Delta, United Airlines, and American Airlines from Sioux Falls to Missouri. Reviews also offer insight into each airline's entertainment options, comfort, food, crew/service, and boarding process.
Delta
8.0
Very good
7,984 reviews

Crew

8.5

Boarding

8.2

Entertainment

7.9

Overall

8.0

Food

7.3

Comfort

7.9

Reviews

1 / 20
8.0
Excellent

Matthew,Oct 2025

GSP - ATL

This is always a full flight since it is the connecting route to primary destinations through Atlanta. That said, the crew handles the full load well. Not much more to say, it is a short flight with no in-flight services due to the length.
Delta
8.0
Very good
7,984 reviews
Delta
8.0
Very good
7,984 reviews

Crew

8.5

Boarding

8.2

Entertainment

7.9

Overall

8.0

Food

7.3

Comfort

7.9

Reviews

1 / 20
8.0
Excellent

Matthew,Oct 2025

GSP - ATL

This is always a full flight since it is the connecting route to primary destinations through Atlanta. That said, the crew handles the full load well. Not much more to say, it is a short flight with no in-flight services due to the length.
United Airlines
7.4
Good
8,982 reviews
Delta
8.0
Very good
7,984 reviews

Crew

8.5

Boarding

8.2

Entertainment

7.9

Overall

8.0

Food

7.3

Comfort

7.9

Reviews

1 / 20
8.0
Excellent

Matthew,Oct 2025

GSP - ATL

This is always a full flight since it is the connecting route to primary destinations through Atlanta. That said, the crew handles the full load well. Not much more to say, it is a short flight with no in-flight services due to the length.
American Airlines
7.2
Good
11,043 reviews
Delta
8.0
Very good
7,984 reviews

Crew

8.5

Boarding

8.2

Entertainment

7.9

Overall

8.0

Food

7.3

Comfort

7.9

Reviews

1 / 20
8.0
Excellent

Matthew,Oct 2025

GSP - ATL

This is always a full flight since it is the connecting route to primary destinations through Atlanta. That said, the crew handles the full load well. Not much more to say, it is a short flight with no in-flight services due to the length.

Related info for your journey

Find useful and relevant information for your journey from Sioux Falls to Missouri. Access travel guides, tips, and recommendations to enhance your travel experience. Get information about local attractions, weather, transportation options, and more.

  • What airport do you fly from for flights from Sioux Falls to Missouri?

    Most people fly from Sioux Falls Joe Foss Field (FSD) if they book a flight from Sioux Falls to Missouri. Sioux Falls Joe Foss Field is conveniently located just 2.6 mi from Sioux Falls’s city center.

  • How long is the flight from Sioux Falls to Missouri?

    A quick flight from Sioux Falls to Missouri can take about 4h 40m. Frontier provides one of the quickest options available for as low as $229. There are 470 mi between Sioux Falls and Missouri. This flight may include one or multiple stops.

  • What are the cheapest airlines to fly from Sioux Falls to Missouri one-way?

    To fly one-way, consider booking your trip with Frontier, which is currently one of the cheapest options available, starting at $245. Delta flights start at $322 while deals on United Airlines start at $357 one-way.

  • What are the most popular routes from Sioux Falls to Missouri?

    The most popular flight routes from Sioux Falls to Missouri are Sioux Falls Joe Foss Field - Lambert-St Louis, Sioux Falls Joe Foss Field - Kansas City and Sioux Falls Joe Foss Field - Springfield-Branson.

  • Can I find deals for flights from Sioux Falls to Missouri that include hotel bookings?

    Yes. In addition to deals on Sioux Falls to Missouri flights, Cheapflights offers vacation packages that include both flights and hotel.

  • How can I find direct flights from Sioux Falls to Missouri?

    After entering your origin and destination, apply the non-stop filter on the search result page to find direct flights from Sioux Falls to Missouri.

  • Can I find deals for business class flights from Sioux Falls to Missouri?

    Yes. Cheapflights offers flight deals from Sioux Falls to Missouri by cabin class. In addition to browsing deals, you can also filter by cabin class on the search results page after making a search.

  • What is the cheapest month to book a flight from Sioux Falls to Missouri?

    Currently, February is the cheapest month in which you can book a flight from Sioux Falls to Missouri (average of $203). Flying from Sioux Falls to Missouri in July is currently the most expensive (average of $313). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.

See more FAQs

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Top 3 airlines flying from Sioux Falls to Missouri

Discover the top 3 airlines that operate flights from Sioux Falls to Missouri. Compare their services, reliability, and customer satisfaction ratings to choose the airline that best suits your travel preferences and needs. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated October 16, 2025.
AirlineCheapestAverageFlexibilityOn-time
American AirlinesCheapest$198Average$348FlexibilityNo cancel feeOn-time71%
DeltaCheapest$228Average$347FlexibilityNo cancel feeOn-timeN/A
United AirlinesCheapest$241Average$365FlexibilityNo cancel feeOn-time69%

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