$80+ Cheap flights from Sioux Falls (FSD) to Missouri
This is the cheapest one-way flight price found by a Cheapflights user in the last 72 hours by searching for a flight departing on 2/26. Fares are subject to change and may not be available on all flights or dates of travel.
FSD — STL
Mar 15 — Mar 221
1 adult, Economy
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Find cheap flights from Sioux Falls to Missouri with Cheapflights
1. Tell us where you want to go
Enter your travel information like dates, passengers, trip type (one-way or round trip), and preferred cabin class then click “Find deals”2. Select your favorite providers
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Cheapest flights from Sioux Falls to MissouriExplore the most affordable flight options available from Sioux Falls to Missouri. Find the lowest fares from popular airlines and budget airlines, with prices last updated on February 13, 2026.
Explore the most affordable flight options available from Sioux Falls to Missouri. Find the lowest fares from popular airlines and budget airlines, with prices last updated on February 13, 2026.
This Frontier deal was found by Cheapflights users on 2/11. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Frontier is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 2/262:16 pm
FSD
- MCI
1 stop6h 13m
Frontier
Wed 3/44:39 pm
MCI
- FSD
1 stop20h 42m
Frontier
Deal found 2/11![Frontier logo]()
$161
This United Airlines deal was found by Cheapflights users on 2/9. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 3/316:00 am
FSD
- SGF
1 stop4h 39m
United Airlines
Sat 4/46:30 pm
SGF
- FSD
1 stop4h 39m
United Airlines
Deal found 2/9![United Airlines logo]()
$249
This American Airlines deal was found by Cheapflights users on 2/11. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 2/267:42 pm
FSD
- STL
1 stop4h 06m
American Airlines
Mon 3/26:36 pm
STL
- FSD
1 stop4h 27m
American Airlines
Deal found 2/11![American Airlines logo]()
$264
This Delta deal was found by Cheapflights users on 2/10. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 2/255:00 am
FSD
- STL
1 stop5h 43m
Delta
Sun 3/16:10 am
STL
- FSD
1 stop3h 58m
Delta
Deal found 2/10![Delta logo]()
$269
This American Airlines deal was found by Cheapflights users on 2/10. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 3/257:42 pm
FSD
- STL
1 stop4h 02m
American Airlines
Sun 3/296:00 am
STL
- FSD
1 stop5h 38m
American Airlines
Deal found 2/10![American Airlines logo]()
$274
This American Airlines deal was found by Cheapflights users on 2/9. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 2/185:44 am
FSD
- SGF
1 stop5h 51m
American Airlines
Tue 3/36:05 pm
SGF
- FSD
1 stop4h 58m
American Airlines
Deal found 2/9![American Airlines logo]()
$274
This American Airlines deal was found by Cheapflights users on 2/11. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 2/267:42 pm
FSD
- MCI
1 stop4h 16m
American Airlines
Mon 3/24:16 pm
MCI
- FSD
1 stop6h 47m
American Airlines
Deal found 2/11![American Airlines logo]()
$279
This Kiwi.com deal was found by Cheapflights users on 2/12. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 2/262:16 pm
FSD
- MCI
1 stop6h 13m
Frontier
Sun 3/11:44 pm
MCI
- FSD
1 stop24h 13m
Frontier
Deal found 2/12![Frontier logo]()
$298
This Delta deal was found by Cheapflights users on 2/12. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 2/191:00 pm
FSD
- STL
1 stop3h 45m
Delta
Sat 2/216:10 am
STL
- FSD
1 stop6h 10m
Delta
Deal found 2/12![Delta logo]()
$299
This American Airlines deal was found by Cheapflights users on 2/11. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 2/185:44 am
FSD
- SGF
1 stop5h 51m
American Airlines
Tue 2/242:19 pm
SGF
- FSD
1 stop7h 21m
American Airlines
Deal found 2/11![American Airlines logo]()
$299
This American Airlines deal was found by Cheapflights users on 2/11. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 2/185:44 am
FSD
- SGF
1 stop5h 51m
American Airlines
Mon 3/26:05 pm
SGF
- FSD
1 stop4h 58m
American Airlines
Deal found 2/11![American Airlines logo]()
$309
This United Airlines deal was found by Cheapflights users on 2/10. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 2/276:45 pm
FSD
- STL
1 stop4h 14m
United Airlines
Sun 3/16:00 pm
STL
- FSD
1 stop5h 49m
United Airlines
Deal found 2/10![United Airlines logo]()
$317
Best flights from Sioux Falls to MissouriDiscover carefully curated flight deals from Sioux Falls to Missouri that have cost, travel time, and layovers in mind to ensure you get the best travel experience. Data last updated February 13, 2026.
Discover carefully curated flight deals from Sioux Falls to Missouri that have cost, travel time, and layovers in mind to ensure you get the best travel experience. Data last updated February 13, 2026.
This Frontier deal was found by Cheapflights users on 2/11. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Frontier is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 2/262:16 pm
FSD
- MCI
1 stop6h 13m
Frontier
Wed 3/44:39 pm
MCI
- FSD
1 stop20h 42m
Frontier
Deal found 2/11![Frontier logo]()
$161
This United Airlines deal was found by Cheapflights users on 2/9. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 3/316:00 am
FSD
- SGF
1 stop4h 39m
United Airlines
Sat 4/46:30 pm
SGF
- FSD
1 stop4h 39m
United Airlines
Deal found 2/9![United Airlines logo]()
$249
This American Airlines deal was found by Cheapflights users on 2/11. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 2/267:42 pm
FSD
- STL
1 stop4h 06m
American Airlines
Mon 3/26:36 pm
STL
- FSD
1 stop4h 27m
American Airlines
Deal found 2/11![American Airlines logo]()
$264
This Delta deal was found by Cheapflights users on 2/10. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 2/255:00 am
FSD
- STL
1 stop5h 43m
Delta
Sun 3/16:10 am
STL
- FSD
1 stop3h 58m
Delta
Deal found 2/10![Delta logo]()
$269
This Kiwi.com deal was found by Cheapflights users on 2/11. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 2/262:16 pm
FSD
- MCI
1 stop6h 13m
Multiple Airlines
Mon 3/28:33 pm
MCI
- FSD
2 stops41h 11m
Multiple Airlines
Deal found 2/11![Multiple Airlines logo]()
$369
This American Airlines deal was found by Cheapflights users on 2/10. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 3/257:42 pm
FSD
- STL
1 stop4h 02m
American Airlines
Sun 3/296:00 am
STL
- FSD
1 stop5h 38m
American Airlines
Deal found 2/10![American Airlines logo]()
$274
This Kiwi.com deal was found by Cheapflights users on 2/12. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 2/262:16 pm
FSD
- MCI
1 stop6h 13m
Frontier
Sun 3/11:44 pm
MCI
- FSD
1 stop24h 13m
Frontier
Deal found 2/12![Frontier logo]()
$298
This American Airlines deal was found by Cheapflights users on 2/11. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 2/277:42 pm
FSD
- MCI
1 stop4h 16m
American Airlines
Mon 3/24:16 pm
MCI
- FSD
1 stop6h 47m
American Airlines
Deal found 2/11![American Airlines logo]()
$279
This United Airlines deal was found by Cheapflights users on 2/10. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 2/276:45 pm
FSD
- STL
1 stop4h 14m
United Airlines
Sun 3/16:00 pm
STL
- FSD
1 stop5h 49m
United Airlines
Deal found 2/10![United Airlines logo]()
$317
This Delta deal was found by Cheapflights users on 2/11. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 3/45:00 am
FSD
- STL
1 stop5h 43m
Delta
Fri 3/65:29 pm
STL
- FSD
1 stop5h 26m
Delta
Deal found 2/11![Delta logo]()
$368
This Kiwi.com deal was found by Cheapflights users on 2/11. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 2/262:16 pm
FSD
- STL
1 stop22h 53m
Multiple Airlines
Mon 3/28:47 pm
STL
- FSD
2 stops40h 57m
Multiple Airlines
Deal found 2/11![Multiple Airlines logo]()
$370
This United Airlines deal was found by Cheapflights users on 2/10. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 3/49:00 am
FSD
- STL
1 stop7h 58m
United Airlines
Fri 3/66:05 pm
STL
- FSD
1 stop5h 39m
United Airlines
Deal found 2/10![United Airlines logo]()
$348
This United Airlines deal was found by Cheapflights users on 2/9. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 2/259:00 am
FSD
- SGF
1 stop7h 21m
United Airlines
Sat 2/285:02 pm
SGF
- FSD
1 stop6h 47m
United Airlines
Deal found 2/9![United Airlines logo]()
$384
This Kiwi.com deal was found by Cheapflights users on 2/10. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 3/259:14 pm
FSD
- STL
1 stop24h 48m
Multiple Airlines
Sun 3/298:06 pm
STL
- FSD
2 stops23h 53m
Multiple Airlines
Deal found 2/10![Multiple Airlines logo]()
$425
This Kiwi.com deal was found by Cheapflights users on 2/10. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 2/271:59 pm
FSD
- STL
1 stop23h 57m
Frontier
Sun 3/110:11 pm
STL
- FSD
2 stops15h 46m
Frontier
Deal found 2/10![Frontier logo]()
$425
This American Airlines deal was found by Cheapflights users on 2/9. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 3/232:06 pm
FSD
- STL
1 stop18h 45m
American Airlines
Wed 3/256:00 am
STL
- FSD
1 stop5h 38m
American Airlines
Deal found 2/9![American Airlines logo]()
$387
This Delta deal was found by Cheapflights users on 2/12. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 4/2110:53 am
FSD
- MCI
2 stops6h 07m
Delta
Fri 4/249:31 am
MCI
- FSD
1 stop6h 06m
Delta
Deal found 2/12![Delta logo]()
$520
This American Airlines deal was found by Cheapflights users on 2/11. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 2/267:42 pm
FSD
- SGF
1 stop14h 08m
American Airlines
Mon 3/26:05 pm
SGF
- FSD
1 stop4h 58m
American Airlines
Deal found 2/11![American Airlines logo]()
$442
This United Airlines deal was found by Cheapflights users on 2/10. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 2/265:50 am
FSD
- MCI
1 stop6h 58m
United Airlines
Mon 3/21:50 pm
MCI
- FSD
1 stop6h 49m
United Airlines
Deal found 2/10![United Airlines logo]()
$450
This Kiwi.com deal was found by Cheapflights users on 2/11. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 2/262:16 pm
FSD
- SGF
2 stops21h 09m
Multiple Airlines
Mon 3/23:32 pm
SGF
- FSD
1 stop19h 40m
Multiple Airlines
Deal found 2/11![Multiple Airlines logo]()
$513
This United Airlines deal was found by Cheapflights users on 2/9. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 5/146:31 pm
FSD
- MCI
1 stop4h 30m
United Airlines
Sun 5/176:00 am
MCI
- FSD
1 stop4h 44m
United Airlines
Deal found 2/9![United Airlines logo]()
$451
This American Airlines deal was found by Cheapflights users on 2/9. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 2/252:08 pm
FSD
- SGF
1 stop8h 27m
American Airlines
Sun 3/17:34 am
SGF
- FSD
1 stop15h 29m
American Airlines
Deal found 2/9![American Airlines logo]()
$496
This United Airlines deal was found by Cheapflights users on 2/11. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 6/106:51 pm
FSD
- SGF
1 stop4h 51m
United Airlines
Sun 6/146:00 am
SGF
- FSD
1 stop15h 38m
United Airlines
Deal found 2/11![United Airlines logo]()
$465
This Delta deal was found by Cheapflights users on 2/11. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 2/261:00 pm
FSD
- MCI
2 stops8h 58m
Delta
Wed 3/46:23 am
MCI
- FSD
1 stop5h 52m
Delta
Deal found 2/11![Delta logo]()
$651
This American Airlines deal was found by Cheapflights users on 2/12. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 2/2812:14 pm
FSD
- SGF
1 stop21h 54m
American Airlines
Wed 3/47:15 am
SGF
- FSD
1 stop5h 26m
American Airlines
Deal found 2/12![American Airlines logo]()
$511
This United Airlines deal was found by Cheapflights users on 2/10. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 2/251:40 pm
FSD
- STL
2 stops8h 34m
United Airlines
Sun 3/16:00 pm
STL
- FSD
1 stop5h 49m
United Airlines
Deal found 2/10![United Airlines logo]()
$472
This American Airlines deal was found by Cheapflights users on 2/11. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 6/1112:02 pm
FSD
- SGF
1 stop7h 21m
American Airlines
Sat 6/1311:00 am
SGF
- FSD
1 stop5h 54m
American Airlines
Deal found 2/11![American Airlines logo]()
$514
This United Airlines deal was found by Cheapflights users on 2/12. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 4/213:10 pm
FSD
- MCI
1 stop6h 49m
United Airlines
Fri 4/243:21 pm
MCI
- FSD
1 stop6h 28m
United Airlines
Deal found 2/12![United Airlines logo]()
$475
This American Airlines deal was found by Cheapflights users on 2/11. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 6/125:34 pm
FSD
- SGF
1 stop6h 03m
American Airlines
Sat 6/1311:00 am
SGF
- FSD
1 stop5h 54m
American Airlines
Deal found 2/11![American Airlines logo]()
$514
This United Airlines deal was found by Cheapflights users on 2/11. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 6/126:00 am
FSD
- SGF
1 stop4h 41m
United Airlines
Sun 6/146:00 am
SGF
- FSD
1 stop15h 38m
United Airlines
Deal found 2/11![United Airlines logo]()
$483
Last-minute flights from Sioux Falls to MissouriDiscover last-minute flight deals from Sioux Falls to Missouri. Data last updated February 13, 2026 and is based on user searches.
Discover last-minute flight deals from Sioux Falls to Missouri. Data last updated February 13, 2026 and is based on user searches.
This American Airlines deal was found by Cheapflights users on 2/9. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 2/185:44 am
FSD
- SGF
1 stop5h 51m
American Airlines
Tue 3/36:05 pm
SGF
- FSD
1 stop4h 58m
American Airlines
Deal found 2/9![American Airlines logo]()
$274
This American Airlines deal was found by Cheapflights users on 2/11. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 2/185:44 am
FSD
- SGF
1 stop5h 51m
American Airlines
Tue 2/242:19 pm
SGF
- FSD
1 stop7h 21m
American Airlines
Deal found 2/11![American Airlines logo]()
$299
This American Airlines deal was found by Cheapflights users on 2/11. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 2/185:44 am
FSD
- SGF
1 stop5h 51m
American Airlines
Mon 3/26:05 pm
SGF
- FSD
1 stop4h 58m
American Airlines
Deal found 2/11![American Airlines logo]()
$309
This Delta deal was found by Cheapflights users on 2/12. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 2/191:00 pm
FSD
- STL
1 stop3h 45m
Delta
Sat 2/216:10 am
STL
- FSD
1 stop6h 10m
Delta
Deal found 2/12![Delta logo]()
$299
This Delta deal was found by Cheapflights users on 2/10. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 2/255:00 am
FSD
- STL
1 stop5h 43m
Delta
Sun 3/16:10 am
STL
- FSD
1 stop3h 58m
Delta
Deal found 2/10![Delta logo]()
$269
This Frontier deal was found by Cheapflights users on 2/11. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Frontier is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 2/262:16 pm
FSD
- MCI
1 stop6h 13m
Frontier
Wed 3/44:39 pm
MCI
- FSD
1 stop20h 42m
Frontier
Deal found 2/11![Frontier logo]()
$161
This American Airlines deal was found by Cheapflights users on 2/11. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 2/267:42 pm
FSD
- STL
1 stop4h 06m
American Airlines
Mon 3/26:36 pm
STL
- FSD
1 stop4h 27m
American Airlines
Deal found 2/11![American Airlines logo]()
$264
This American Airlines deal was found by Cheapflights users on 2/11. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 2/267:42 pm
FSD
- MCI
1 stop4h 16m
American Airlines
Mon 3/24:16 pm
MCI
- FSD
1 stop6h 47m
American Airlines
Deal found 2/11![American Airlines logo]()
$279
This Kiwi.com deal was found by Cheapflights users on 2/12. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 2/262:16 pm
FSD
- MCI
1 stop6h 13m
Frontier
Sun 3/11:44 pm
MCI
- FSD
1 stop24h 13m
Frontier
Deal found 2/12![Frontier logo]()
$298
This United Airlines deal was found by Cheapflights users on 2/10. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 2/276:45 pm
FSD
- STL
1 stop4h 14m
United Airlines
Sun 3/16:00 pm
STL
- FSD
1 stop5h 49m
United Airlines
Deal found 2/10![United Airlines logo]()
$317
This American Airlines deal was found by Cheapflights users on 2/10. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 3/257:42 pm
FSD
- STL
1 stop4h 02m
American Airlines
Sun 3/296:00 am
STL
- FSD
1 stop5h 38m
American Airlines
Deal found 2/10![American Airlines logo]()
$274
This United Airlines deal was found by Cheapflights users on 2/9. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 3/316:00 am
FSD
- SGF
1 stop4h 39m
United Airlines
Sat 4/46:30 pm
SGF
- FSD
1 stop4h 39m
United Airlines
Deal found 2/9![United Airlines logo]()
$249
One-way flights from Sioux Falls to MissouriSearch for one-way flight options from Sioux Falls to Missouri. Find affordable one-way fares based on user searches. Data last updated February 13, 2026.
Search for one-way flight options from Sioux Falls to Missouri. Find affordable one-way fares based on user searches. Data last updated February 13, 2026.
This Priceline deal was found by Cheapflights users on 2/12. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Priceline is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 2/262:16 pm
FSD
- MCI
1 stop6h 13m
Frontier
Deal found 2/12![Frontier logo]()
$80
This Kiwi.com deal was found by Cheapflights users on 2/11. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 3/96:37 pm
FSD
- MCI
2 stops20h 52m
Multiple Airlines
Deal found 2/11![Multiple Airlines logo]()
$157
This Kiwi.com deal was found by Cheapflights users on 2/12. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 3/1112:56 pm
FSD
- MCI
1 stop19h 08m
Allegiant Air
Deal found 2/12![Allegiant Air logo]()
$173
This American Airlines deal was found by Cheapflights users on 2/10. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 3/127:42 pm
FSD
- MCI
1 stop13h 00m
American Airlines
Deal found 2/10![American Airlines logo]()
$234
This American Airlines deal was found by Cheapflights users on 2/12. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 7/135:34 pm
FSD
- STL
1 stop6h 10m
American Airlines
Deal found 2/12![American Airlines logo]()
$238
This United Airlines deal was found by Cheapflights users on 2/11. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 3/99:00 am
FSD
- MCI
1 stop7h 19m
United Airlines
Deal found 2/11![United Airlines logo]()
$238
This United Airlines deal was found by Cheapflights users on 2/11. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 2/281:40 pm
FSD
- MCI
1 stop6h 55m
United Airlines
Deal found 2/11![United Airlines logo]()
$290
This Delta deal was found by Cheapflights users on 2/11. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 2/281:05 pm
FSD
- MCI
2 stops8h 02m
Delta
Deal found 2/11![Delta logo]()
$300
This Kiwi.com deal was found by Cheapflights users on 2/12. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 3/119:14 pm
FSD
- MCI
3 stops46h 41m
Multiple Airlines
Deal found 2/12![Multiple Airlines logo]()
$316
This Kiwi.com deal was found by Cheapflights users on 2/12. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 2/262:16 pm
FSD
- MCI
3 stops20h 14m
Multiple Airlines
Deal found 2/12![Multiple Airlines logo]()
$327
This United Airlines deal was found by Cheapflights users on 2/10. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 2/229:00 am
FSD
- STL
1 stop7h 58m
United Airlines
Deal found 2/10![United Airlines logo]()
$337
This Kiwi.com deal was found by Cheapflights users on 2/11. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 2/288:21 pm
FSD
- MCI
3 stops47h 27m
Multiple Airlines
Deal found 2/11![Multiple Airlines logo]()
$338
Find flight deals from Sioux Falls to Missouri
Keep the following information in mind while searching for Sioux Falls to Missouri flight deals. Data was last updated February 13, 2026.
Most accurate provider | FlightHub 3 stars |
|---|---|
Most trusted provider | FlightHub 3 stars |
Round-trip from | $161 (Frontier) |
One-way from | $80 (Priceline) |
Popular in | July |
Cheapest in | September |
Average price | $298 |
Cheapflights Fare Finder
Customize your flight search to find flights from Sioux Falls to Missouri that fit within your specific budget. Explore options based on user searches and filter the results based on your desired price range. Find flights that match your budget for a cost-effective journey. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated February 13, 2026.
Use the filters below to find and compare flights from Sioux Falls to Missouri that are best for you.
Fly from
Sioux Falls
Fly to
Missouri
Route
Depart
Return
Price
Sioux FallsKansas City
FSD - MCI
FSDMCI
Sioux Falls Joe Foss Field
Thu 2/26
2:16 pm-8:29 pm
1 stop6h 13m
Kansas City
Wed 3/4
4:39 pm-1:21 pm
1 stop20h 42m
$161
Sioux FallsSpringfield
FSD - SGF
FSDSGF
Sioux Falls Joe Foss Field
Tue 3/31
6:00 am-10:39 am
1 stop4h 39m
Springfield-Branson
Sat 4/4
6:30 pm-11:09 pm
1 stop4h 39m
$249
Sioux FallsSt. Louis
FSD - STL
FSDSTL
Sioux Falls Joe Foss Field
Thu 2/26
7:42 pm-11:48 pm
1 stop4h 06m
Lambert-St Louis
Mon 3/2
6:36 pm-11:03 pm
1 stop4h 27m
$264
Sioux FallsSt. Louis
FSD - STL
FSDSTL
Sioux Falls Joe Foss Field
Wed 2/25
5:00 am-10:43 am
1 stop5h 43m
Lambert-St Louis
Sun 3/1
6:10 am-10:08 am
1 stop3h 58m
$269
Sioux FallsSt. Louis
FSD - STL
FSDSTL
Sioux Falls Joe Foss Field
Wed 3/25
7:42 pm-11:44 pm
1 stop4h 02m
Lambert-St Louis
Sun 3/29
6:00 am-11:38 am
1 stop5h 38m
$274
Sioux FallsKansas City
FSD - MCI
FSDMCI
Sioux Falls Joe Foss Field
Fri 2/27
7:42 pm-11:58 pm
1 stop4h 16m
Kansas City
Mon 3/2
4:16 pm-11:03 pm
1 stop6h 47m
$279
Sioux FallsKansas City
FSD - MCI
FSDMCI
Sioux Falls Joe Foss Field
Thu 2/26
2:16 pm-8:29 pm
1 stop6h 13m
Kansas City
Sun 3/1
1:44 pm-1:57 pm
1 stop24h 13m
$298
Sioux FallsSt. Louis
FSD - STL
FSDSTL
Sioux Falls Joe Foss Field
Fri 2/27
6:45 pm-10:59 pm
1 stop4h 14m
Lambert-St Louis
Sun 3/1
6:00 pm-11:49 pm
1 stop5h 49m
$317
Sioux FallsSt. Louis
FSD - STL
FSDSTL
Sioux Falls Joe Foss Field
Wed 3/4
9:00 am-4:58 pm
1 stop7h 58m
Lambert-St Louis
Fri 3/6
6:05 pm-11:44 pm
1 stop5h 39m
$348
Sioux FallsSt. Louis
FSD - STL
FSDSTL
Sioux Falls Joe Foss Field
Wed 3/4
5:00 am-10:43 am
1 stop5h 43m
Lambert-St Louis
Fri 3/6
5:29 pm-10:55 pm
1 stop5h 26m
$368
Showing 1-10 of 46 results
Best time to book a flight from Sioux Falls to Missouri
Have a flexible travel schedule? Discover the best time to fly to Missouri from Sioux Falls with our price prediction graph.
FSD-MCI
FSD-SGF
FSD-STL
Estimated round-trip price
Rates are based on past data. Find the cheapest month and day to book your flight based on your travel requirements, then search for cheap deals.
Cheapflights Insights
Everything you need to know about your flight from Sioux Falls to Missouri
FSD-USMO
FSD-MCI
FSD-SGF
FSD-STL
What is the cheapest month to book a flight from Sioux Falls to Missouri?
Currently, February is the cheapest month in which you can book a flight from Sioux Falls to Missouri (average of $225). Flying from Sioux Falls to Missouri in November is currently the most expensive (average of $318). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.
How much does it cost to fly round-trip from Sioux Falls to Missouri?
Reviews of airlines servicing Missouri
Get insights into the airlines that provide service to Missouri. Read reviews, discover amenities, and learn about the overall travel experience offered by airlines. Use this information to make informed decisions when choosing an airline for your flight to Missouri. Reviews last updated February 13, 2026.
Read reviews from past customers who have flown Delta, United Airlines, and American Airlines from Sioux Falls to Missouri. Reviews also offer insight into each airline's entertainment options, comfort, food, crew/service, and boarding process.
Crew
8.5
Overall
7.9
Comfort
7.9
Food
7.2
Boarding
8.1
Entertainment
7.8
Reviews
1 / 20
6.0
GoodJim,Nov 2025
AVL - ATL
Crew
8.5
Overall
7.9
Comfort
7.9
Food
7.2
Boarding
8.1
Entertainment
7.8
Reviews
1 / 20
6.0
GoodJim,Nov 2025
AVL - ATL
Crew
8.5
Overall
7.9
Comfort
7.9
Food
7.2
Boarding
8.1
Entertainment
7.8
Reviews
1 / 20
6.0
GoodJim,Nov 2025
AVL - ATL
Crew
8.5
Overall
7.9
Comfort
7.9
Food
7.2
Boarding
8.1
Entertainment
7.8
Reviews
1 / 20
6.0
GoodJim,Nov 2025
AVL - ATL
Related info for your journey
Find useful and relevant information for your journey from Sioux Falls to Missouri. Access travel guides, tips, and recommendations to enhance your travel experience. Get information about local attractions, weather, transportation options, and more.
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Complete your trip
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Sioux Falls and Missouri flights
Browse other Sioux Falls and Missouri flight options. Last updated on February 13, 2026.
Popular flight searches
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Sioux Falls to Missouri flights
Consider these flights traveling from Sioux Falls to Missouri.
Top 3 airlines flying from Sioux Falls to Missouri
Discover the top 3 airlines that operate flights from Sioux Falls to Missouri. Compare their services, reliability, and customer satisfaction ratings to choose the airline that best suits your travel preferences and needs. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated February 13, 2026.
| Airline | Cheapest | Average | Flexibility | On-time |
|---|---|---|---|---|
| Cheapest$198 | Average$372 | FlexibilityNo cancel fee | On-time71% | |
| Cheapest$228 | Average$338 | FlexibilityNo cancel fee | On-timeN/A | |
| Cheapest$268 | Average$309 | FlexibilityNo cancel fee | On-time69% |