HomeSearch by dateVacation packagesHotelsFlight dealsCar rentalTravel tips & news
Missouri

$80+ Cheap flights from Sioux Falls (FSD) to Missouri

This is the cheapest one-way flight price found by a Cheapflights user in the last 72 hours by searching for a flight departing on 2/19. Fares are subject to change and may not be available on all flights or dates of travel.
FSD — STL
Feb 24 — Mar 31
Tue 2/24
Tue 3/3
1 adult, Economy
We work with more than 300 partners to bring you better travel deals

Find cheap flights from Sioux Falls to Missouri with Cheapflights

1. Tell us where you want to go

Enter your travel information like dates, passengers, trip type (one-way or round trip), and preferred cabin class then click “Find deals”

2. Select your favorite providers

We find the providers serving your travel needs. Choose up to four travel providers to compare side-by-side for flights, hotels, or car rentals.

3. Compare prices and book

Review each provider’s pricing and select the best option for you! Book through your favorite provider’s website for a seamless experience.

Cheap flight deals from Sioux Falls to Missouri

Cheapest flights from Sioux Falls to Missouri
Explore the most affordable flight options available from Sioux Falls to Missouri. Find the lowest fares from popular airlines and budget airlines, with prices last updated on January 25, 2026.

This American Airlines deal was found by Cheapflights users on 1/23. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 2/197:42 pm
FSD
-
STL
1 stop4h 06m
American Airlines
Sat 2/218:00 am
STL
-
FSD
1 stop5h 33m
American Airlines
Deal found 1/23$249
This American Airlines deal was found by Cheapflights users on 1/23. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 2/207:42 pm
FSD
-
MCI
1 stop4h 16m
American Airlines
Fri 2/276:40 am
MCI
-
FSD
1 stop6h 01m
American Airlines
Deal found 1/23$249
This Delta deal was found by Cheapflights users on 1/22. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 2/711:00 am
FSD
-
STL
1 stop3h 38m
Delta
Wed 2/116:10 am
STL
-
FSD
1 stop6h 12m
Delta
Deal found 1/22$259
This Delta deal was found by Cheapflights users on 1/24. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 3/149:50 am
FSD
-
STL
1 stop4h 34m
Delta
Fri 3/205:25 pm
STL
-
FSD
1 stop5h 39m
Delta
Deal found 1/24$284
This American Airlines deal was found by Cheapflights users on 1/23. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 2/115:38 pm
FSD
-
SGF
1 stop5h 09m
American Airlines
Sun 2/157:15 am
SGF
-
FSD
1 stop5h 26m
American Airlines
Deal found 1/23$284
This United Airlines deal was found by Cheapflights users on 1/23. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 1/233:11 pm
FSD
-
MCI
1 stop6h 48m
United Airlines
Sun 1/2510:00 am
MCI
-
FSD
1 stop4h 36m
United Airlines
Deal found 1/23$319
This Kiwi.com deal was found by Cheapflights users on 1/23. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 2/271:59 pm
FSD
-
MCI
1 stop5h 49m
Multiple Airlines
Mon 3/28:33 pm
MCI
-
FSD
2 stops41h 11m
Multiple Airlines
Deal found 1/23$346
This American Airlines deal was found by Cheapflights users on 1/24. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 4/27:42 pm
FSD
-
STL
1 stop4h 06m
American Airlines
Mon 4/66:00 am
STL
-
FSD
1 stop5h 38m
American Airlines
Deal found 1/24$349
This United Airlines deal was found by Cheapflights users on 1/22. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 4/104:57 pm
FSD
-
MCI
1 stop6h 35m
United Airlines
Mon 4/133:21 pm
MCI
-
FSD
1 stop6h 28m
United Airlines
Deal found 1/22$351
This United Airlines deal was found by Cheapflights users on 1/23. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 3/23:15 pm
FSD
-
STL
1 stop5h 50m
United Airlines
Wed 3/42:45 pm
STL
-
FSD
1 stop5h 54m
United Airlines
Deal found 1/23$363
This United Airlines deal was found by Cheapflights users on 1/22. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 1/271:40 pm
FSD
-
STL
1 stop7h 18m
United Airlines
Sat 1/318:05 am
STL
-
FSD
1 stop6h 31m
United Airlines
Deal found 1/22$369
This United Airlines deal was found by Cheapflights users on 1/22. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 1/279:00 am
FSD
-
SGF
1 stop7h 22m
United Airlines
Sat 1/317:45 am
SGF
-
FSD
1 stop6h 51m
United Airlines
Deal found 1/22$369

Find flight deals from Sioux Falls to Missouri

Keep the following information in mind while searching for Sioux Falls to Missouri flight deals. Data was last updated January 25, 2026.

Most accurate provider

FlightHub
3 stars

Most trusted provider

Expedia
3 stars

Round-trip from

$249
(American Airlines)

One-way from

$80
(Priceline)

Popular in

July

Cheapest in

August

Average price

$349
Provider with most accurate pricing for Sioux Falls Joe Foss Field-Lambert-St Louis flight deals.
Search Deals
Provider most trusted by Cheapflights users for Sioux Falls Joe Foss Field-Lambert-St Louis flights.
Search Deals
From Sioux Falls Joe Foss Field to Missouri
Search Deals
One-way flight from Sioux Falls Joe Foss Field to Missouri
Search Deals
High demand for flights, 0% potential price rise
Search Deals
Cheapest flight prices on average. 2% potential price decrease ($9 potential savings vs. average RT price).
Search Deals
Average for round-trip flights in January 2026
Search Deals

Cheapflights Fare Finder

 
Customize your flight search to find flights from Sioux Falls to Missouri that fit within your specific budget. Explore options based on user searches and filter the results based on your desired price range. Find flights that match your budget for a cost-effective journey. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated January 25, 2026.
Use the filters below to find and compare flights from Sioux Falls to Missouri that are best for you.

Fly from

Sioux Falls

Fly to

Missouri

Route

Depart

Return

Price

Sioux FallsSt. Louis

FSD - STL

FSDSTL

Sioux Falls Joe Foss Field

Thu 2/19

7:42 pm-11:48 pm

1 stop4h 06m

Lambert-St Louis

Sat 2/21

8:00 am-1:33 pm

1 stop5h 33m

$249

Sioux FallsSt. Louis

FSD - STL

FSDSTL

Sioux Falls Joe Foss Field

Sat 2/21

2:07 pm-9:12 pm

1 stop7h 05m

Lambert-St Louis

Sat 2/28

8:00 am-1:33 pm

1 stop5h 33m

$249

Sioux FallsSt. Louis

FSD - STL

FSDSTL

Sioux Falls Joe Foss Field

Sat 2/14

12:14 pm-6:00 pm

1 stop5h 46m

Lambert-St Louis

Sat 2/21

8:00 am-1:33 pm

1 stop5h 33m

$249

Sioux FallsKansas City

FSD - MCI

FSDMCI

Sioux Falls Joe Foss Field

Fri 2/20

7:42 pm-11:58 pm

1 stop4h 16m

Kansas City

Fri 2/27

6:40 am-12:41 pm

1 stop6h 01m

$249

Sioux FallsKansas City

FSD - MCI

FSDMCI

Sioux Falls Joe Foss Field

Fri 2/27

7:42 pm-11:58 pm

1 stop4h 16m

Kansas City

Mon 3/2

1:58 pm-9:40 pm

1 stop7h 42m

$249

Sioux FallsSt. Louis

FSD - STL

FSDSTL

Sioux Falls Joe Foss Field

Sat 2/7

11:00 am-2:38 pm

1 stop3h 38m

Lambert-St Louis

Wed 2/11

6:10 am-12:22 pm

1 stop6h 12m

$259

Sioux FallsSt. Louis

FSD - STL

FSDSTL

Sioux Falls Joe Foss Field

Sat 3/14

9:50 am-2:24 pm

1 stop4h 34m

Lambert-St Louis

Fri 3/20

5:25 pm-11:04 pm

1 stop5h 39m

$284

Sioux FallsSpringfield

FSD - SGF

FSDSGF

Sioux Falls Joe Foss Field

Wed 2/11

5:38 pm-10:47 pm

1 stop5h 09m

Springfield-Branson

Sun 2/15

7:15 am-12:41 pm

1 stop5h 26m

$284

Sioux FallsKansas City

FSD - MCI

FSDMCI

Sioux Falls Joe Foss Field

Sat 2/7

5:18 pm-11:30 pm

1 stop6h 12m

Kansas City

Wed 2/11

10:00 am-5:18 pm

1 stop7h 18m

$319

Sioux FallsSt. Louis

FSD - STL

FSDSTL

Sioux Falls Joe Foss Field

Fri 4/3

2:06 pm-9:11 pm

1 stop7h 05m

Lambert-St Louis

Mon 4/6

5:12 am-12:41 pm

1 stop7h 29m

$349

Flights are sorted by cheapest round-trip flights first.

Deals found on 1/24

Showing 1-10 of 32 results
1
2
3
4

Best time to book a flight from Sioux Falls to Missouri

Have a flexible travel schedule? Discover the best time to fly to Missouri from Sioux Falls with our price prediction graph.
Estimated round-trip price
Rates are based on past data. Find the cheapest month and day to book your flight based on your travel requirements, then search for cheap deals.

Cheapflights Insights

Everything you need to know about your flight from Sioux Falls to Missouri

What is the cheapest month to book a flight from Sioux Falls to Missouri?

Currently, February is the cheapest month in which you can book a flight from Sioux Falls to Missouri (average of $205). Flying from Sioux Falls to Missouri in November is currently the most expensive (average of $318). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.

Reviews of airlines servicing Missouri

Get insights into the airlines that provide service to Missouri. Read reviews, discover amenities, and learn about the overall travel experience offered by airlines. Use this information to make informed decisions when choosing an airline for your flight to Missouri. Reviews last updated January 25, 2026.
Read reviews from past customers who have flown Delta, United Airlines, and American Airlines from Sioux Falls to Missouri. Reviews also offer insight into each airline's entertainment options, comfort, food, crew/service, and boarding process.
Delta
7.9
Good
8,111 reviews

Boarding

8.1

Crew

8.5

Overall

7.9

Food

7.2

Entertainment

7.8

Comfort

7.9

Reviews

1 / 20
6.0
Good

Jim,Nov 2025

AVL - ATL

The exit row seats without a seat in front are great for leg room but don’t have a fold out entertainment console so you’re forced to use the screen several feet in front of you (there is, at least, a remote). Best to bring a tablet loaded with entertainment or a book.
Delta
7.9
Good
8,111 reviews
Delta
7.9
Good
8,111 reviews

Boarding

8.1

Crew

8.5

Overall

7.9

Food

7.2

Entertainment

7.8

Comfort

7.9

Reviews

1 / 20
6.0
Good

Jim,Nov 2025

AVL - ATL

The exit row seats without a seat in front are great for leg room but don’t have a fold out entertainment console so you’re forced to use the screen several feet in front of you (there is, at least, a remote). Best to bring a tablet loaded with entertainment or a book.
United Airlines
7.4
Good
9,198 reviews
Delta
7.9
Good
8,111 reviews

Boarding

8.1

Crew

8.5

Overall

7.9

Food

7.2

Entertainment

7.8

Comfort

7.9

Reviews

1 / 20
6.0
Good

Jim,Nov 2025

AVL - ATL

The exit row seats without a seat in front are great for leg room but don’t have a fold out entertainment console so you’re forced to use the screen several feet in front of you (there is, at least, a remote). Best to bring a tablet loaded with entertainment or a book.
American Airlines
7.2
Good
11,197 reviews
Delta
7.9
Good
8,111 reviews

Boarding

8.1

Crew

8.5

Overall

7.9

Food

7.2

Entertainment

7.8

Comfort

7.9

Reviews

1 / 20
6.0
Good

Jim,Nov 2025

AVL - ATL

The exit row seats without a seat in front are great for leg room but don’t have a fold out entertainment console so you’re forced to use the screen several feet in front of you (there is, at least, a remote). Best to bring a tablet loaded with entertainment or a book.

Related info for your journey

Find useful and relevant information for your journey from Sioux Falls to Missouri. Access travel guides, tips, and recommendations to enhance your travel experience. Get information about local attractions, weather, transportation options, and more.

  • What airport do you fly from for flights from Sioux Falls to Missouri?

    Most people fly from Sioux Falls Joe Foss Field (FSD) if they book a flight from Sioux Falls to Missouri. Sioux Falls Joe Foss Field is conveniently located just 2.6 mi from Sioux Falls’s city center.

  • How long is the flight from Sioux Falls to Missouri?

    A quick flight from Sioux Falls to Missouri can take about 3h 38m. American Airlines provides one of the quickest options available for as low as $259. There are 470 mi between Sioux Falls and Missouri. This flight may include one or multiple stops.

  • What are the most popular routes from Sioux Falls to Missouri?

    The most popular flight routes from Sioux Falls to Missouri are Sioux Falls Joe Foss Field - Lambert-St Louis, Sioux Falls Joe Foss Field - Kansas City and Sioux Falls Joe Foss Field - Springfield-Branson.

  • Can I find deals for flights from Sioux Falls to Missouri that include hotel bookings?

    Yes. In addition to deals on Sioux Falls to Missouri flights, Cheapflights offers vacation packages that include both flights and hotel.

  • How can I find direct flights from Sioux Falls to Missouri?

    After entering your origin and destination, apply the non-stop filter on the search result page to find direct flights from Sioux Falls to Missouri.

  • Can I find deals for business class flights from Sioux Falls to Missouri?

    Yes. Cheapflights offers flight deals from Sioux Falls to Missouri by cabin class. In addition to browsing deals, you can also filter by cabin class on the search results page after making a search.

  • What is the cheapest month to book a flight from Sioux Falls to Missouri?

    Currently, February is the cheapest month in which you can book a flight from Sioux Falls to Missouri (average of $205). Flying from Sioux Falls to Missouri in November is currently the most expensive (average of $318). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.

See more FAQs

Browse thousands of different options on Cheapflights for your next trip

Toggle through the tabs below to find thousands of options on Cheapflights for your next trip.

Alternative routes for Sioux Falls to Missouri

See prices for flight routes from nearby airports that may be better suited for you.
Sioux Falls to Denver flights
Sioux Falls to Sky Harbor Intl flights
Sioux Falls to Dallas/Fort Worth flights
Sioux Falls to Orlando flights
Sioux Falls to Phoenix-Mesa Gateway flights
Sioux Falls to Miami flights
Sioux Falls to O'Hare Intl flights
Sioux Falls to Las Vegas flights
Rapid City to Orlando flights
Sioux Falls to Fort Myers flights
Sioux Falls to Seattle flights
Sioux Falls to Hobby flights
Rapid City to O'Hare Intl flights
Sioux Falls to San Diego flights
Sioux Falls to Sarasota flights
Sioux Falls to Tampa flights
Sioux Falls to Los Angeles flights
Sioux Falls to Pensacola flights
Sioux Falls to Salt Lake City flights
Sioux Falls to John F Kennedy Intl flights
Sioux Falls to Portland flights
Sioux Falls to Atlanta flights
Sioux Falls to LaGuardia flights
Rapid City to Dallas/Fort Worth flights
Rapid City to Fort Lauderdale flights
Rapid City to Denver flights
Sioux Falls to George Bush Intcntl flights
Rapid City to Midway flights
Sioux Falls to West Palm Beach flights
Rapid City to Las Vegas flights
Rapid City to Seattle flights
Rapid City to Sky Harbor Intl flights
Rapid City to Miami flights
Sioux Falls to Midway flights
Sioux Falls to Newark flights
Sioux Falls to Jacksonville flights
Sioux Falls to Spokane flights
Sioux Falls to Charlotte flights
Rapid City to Los Angeles flights
Sioux Falls to Honolulu flights
Rapid City to Atlanta flights
Sioux Falls to Key West flights
Sioux Falls to Nashville flights
Rapid City to Fort Myers flights
Sioux Falls to San Antonio flights
Sioux Falls to New Orleans flights
Sioux Falls to Boston flights
Sioux Falls to Savannah flights
Rapid City to Philadelphia flights
Sioux Falls to Fort Lauderdale flights

Top 3 airlines flying from Sioux Falls to Missouri

Discover the top 3 airlines that operate flights from Sioux Falls to Missouri. Compare their services, reliability, and customer satisfaction ratings to choose the airline that best suits your travel preferences and needs. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated January 25, 2026.
AirlineCheapestAverageFlexibilityOn-time
American AirlinesCheapest$198Average$372FlexibilityNo cancel feeOn-time71%
DeltaCheapest$228Average$338FlexibilityNo cancel feeOn-timeN/A
United AirlinesCheapest$268Average$309FlexibilityNo cancel feeOn-time69%

100% Free

Cheapflights is completely free to use, so you can start saving the moment you arrive.

Book with Flexibility

Our users can plan ahead with confidence and find flights with no change fees

Travel Smart

Millions of people come to us for their flight needs every year. We help make travel planning easy by providing useful insights and data-driven graphs that can inform your decisions.