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$149+ Cheap flights from Sioux Falls (FSD) to Missouri

This is the cheapest one-way flight price found by a Cheapflights user in the last 72 hours by searching for a flight departing on 2/6. Fares are subject to change and may not be available on all flights or dates of travel.
FSD — STL
Feb 5 — Feb 121
Thu 2/5
Thu 2/12
1 adult, Economy
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Cheap flight deals from Sioux Falls to Missouri

Keep the following information in mind while searching for Sioux Falls to Missouri flight deals. Data was last updated January 6, 2026.

Most accurate provider

eDreams
3 stars

Most trusted provider

eDreams
3 stars

Round-trip from

$249
(United Airlines)

One-way from

$149
(Kiwi.com)

Popular in

March

Cheapest in

August
Provider with most accurate pricing for Sioux Falls Joe Foss Field-Lambert-St Louis flight deals.
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Provider most trusted by Cheapflights users for Sioux Falls Joe Foss Field-Lambert-St Louis flights.
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From Sioux Falls Joe Foss Field to Missouri
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One-way flight from Sioux Falls Joe Foss Field to Missouri
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High demand for flights, 1% potential price rise
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Cheapest flight prices on average. 3% potential price decrease ($12 potential savings vs. average RT price).
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Find flight deals from Sioux Falls to Missouri

Cheapest flights from Sioux Falls to Missouri
Explore the most affordable flight options available from Sioux Falls to Missouri. Find the lowest fares from popular airlines and budget airlines, with prices last updated on January 6, 2026.

This United Airlines deal was found by Cheapflights users on 1/4. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 1/286:00 amFSD - STL
1 stop7h 16mUnited Airlines
Mon 2/24:15 pmSTL - FSD
1 stop7h 29mUnited Airlines
Deal found 1/4$249
This American Airlines deal was found by Cheapflights users on 1/5. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 3/312:14 pmFSD - SGF
1 stop5h 21mAmerican Airlines
Sat 3/77:15 amSGF - FSD
1 stop5h 27mAmerican Airlines
Deal found 1/5$249
This American Airlines deal was found by Cheapflights users on 1/5. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 3/65:20 pmFSD - MCI
1 stop6h 55mAmerican Airlines
Mon 3/96:40 amMCI - FSD
1 stop6h 01mAmerican Airlines
Deal found 1/5$249
This United Airlines deal was found by Cheapflights users on 1/4. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 1/236:00 amFSD - STL
1 stop7h 16mUnited Airlines
Mon 1/264:15 pmSTL - FSD
1 stop7h 29mUnited Airlines
Deal found 1/4$254
This United Airlines deal was found by Cheapflights users on 1/5. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 1/207:30 amFSD - SGF
1 stop7h 08mUnited Airlines
Sat 1/247:45 amSGF - FSD
1 stop6h 51mUnited Airlines
Deal found 1/5$259
This Delta deal was found by Cheapflights users on 1/5. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 3/238:00 amFSD - STL
1 stop6h 24mDelta
Sun 3/296:29 amSTL - FSD
1 stop3h 52mDelta
Deal found 1/5$274
This American Airlines deal was found by Cheapflights users on 1/5. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 1/205:35 pmFSD - STL
1 stop5h 24mAmerican Airlines
Sat 1/243:54 pmSTL - FSD
1 stop6h 10mAmerican Airlines
Deal found 1/5$279
This American Airlines deal was found by Cheapflights users on 1/4. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 1/166:15 pmFSD - MCI
1 stop4h 24mAmerican Airlines
Mon 1/1911:55 amMCI - FSD
1 stop4h 58mAmerican Airlines
Deal found 1/4$279
This United Airlines deal was found by Cheapflights users on 1/5. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 1/177:30 amFSD - STL
1 stop4h 59mUnited Airlines
Wed 1/216:00 pmSTL - FSD
1 stop5h 44mUnited Airlines
Deal found 1/5$304
This United Airlines deal was found by Cheapflights users on 1/6. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 1/287:30 amFSD - SGF
1 stop7h 08mUnited Airlines
Sun 2/13:14 pmSGF - FSD
1 stop6h 36mUnited Airlines
Deal found 1/6$305
This United Airlines deal was found by Cheapflights users on 1/5. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 1/96:00 amFSD - SGF
1 stop6h 46mUnited Airlines
Mon 1/123:14 pmSGF - FSD
1 stop6h 36mUnited Airlines
Deal found 1/5$309
This United Airlines deal was found by Cheapflights users on 1/5. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 1/239:00 amFSD - MCI
1 stop7h 08mUnited Airlines
Tue 1/279:05 amMCI - FSD
1 stop7h 32mUnited Airlines
Deal found 1/5$314

Cheapflights Fare Finder

 
Customize your flight search to find flights from Sioux Falls to Missouri that fit within your specific budget. Explore options based on user searches and filter the results based on your desired price range. Find flights that match your budget for a cost-effective journey. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated January 6, 2026.
Use the filters below to find and compare flights from Sioux Falls to Missouri that are best for you.

Fly from

Sioux Falls

Fly to

Missouri

Route

Depart

Return

Price

Sioux FallsSt. Louis

FSD - STL

FSDSTL

Sioux Falls Joe Foss Field

Thu 2/12

7:42 pm-11:48 pm

1 stop4h 06m

Lambert-St Louis

Sun 2/15

9:20 am-1:36 pm

1 stop4h 16m

$249

Sioux FallsSt. Louis

FSD - STL

FSDSTL

Sioux Falls Joe Foss Field

Wed 1/28

6:00 am-1:16 pm

1 stop7h 16m

Lambert-St Louis

Mon 2/2

4:15 pm-11:44 pm

1 stop7h 29m

$249

Sioux FallsSt. Louis

FSD - STL

FSDSTL

Sioux Falls Joe Foss Field

Fri 2/13

7:42 pm-11:35 pm

1 stop3h 53m

Lambert-St Louis

Sun 2/15

8:00 am-1:36 pm

1 stop5h 36m

$249

Sioux FallsSt. Louis

FSD - STL

FSDSTL

Sioux Falls Joe Foss Field

Fri 1/23

6:00 am-1:16 pm

1 stop7h 16m

Lambert-St Louis

Mon 1/26

4:15 pm-11:44 pm

1 stop7h 29m

$254

Sioux FallsSpringfield

FSD - SGF

FSDSGF

Sioux Falls Joe Foss Field

Tue 1/20

7:30 am-2:38 pm

1 stop7h 08m

Springfield-Branson

Sat 1/24

7:45 am-2:36 pm

1 stop6h 51m

$259

Sioux FallsSt. Louis

FSD - STL

FSDSTL

Sioux Falls Joe Foss Field

Mon 3/23

8:00 am-2:24 pm

1 stop6h 24m

Lambert-St Louis

Sun 3/29

6:29 am-10:21 am

1 stop3h 52m

$274

Sioux FallsKansas City

FSD - MCI

FSDMCI

Sioux Falls Joe Foss Field

Fri 1/16

6:15 pm-10:39 pm

1 stop4h 24m

Kansas City

Mon 1/19

11:55 am-4:53 pm

1 stop4h 58m

$279

Sioux FallsSt. Louis

FSD - STL

FSDSTL

Sioux Falls Joe Foss Field

Sat 1/17

7:30 am-12:29 pm

1 stop4h 59m

Lambert-St Louis

Wed 1/21

2:45 pm-8:24 pm

1 stop5h 39m

$304

Sioux FallsKansas City

FSD - MCI

FSDMCI

Sioux Falls Joe Foss Field

Fri 1/23

1:40 pm-8:33 pm

1 stop6h 53m

Kansas City

Tue 1/27

1:42 pm-8:24 pm

1 stop6h 42m

$314

Sioux FallsSt. Louis

FSD - STL

FSDSTL

Sioux Falls Joe Foss Field

Wed 1/21

9:00 am-4:55 pm

1 stop7h 55m

Lambert-St Louis

Sun 1/25

6:00 pm-11:44 pm

1 stop5h 44m

$319

Flights are sorted by cheapest round-trip flights first.

Deals found on 1/3

Showing 1-10 of 31 results
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Best time to book a flight from Sioux Falls to Missouri

Have a flexible travel schedule? Discover the best time to fly to Missouri from Sioux Falls with our price prediction graph.
Estimated round-trip price
Rates are based on past data. Find the cheapest month and day to book your flight based on your travel requirements, then search for cheap deals.

Cheapflights Insights

Everything you need to know about your flight from Sioux Falls to Missouri
No data available for this route at this time. Please check back soon.

Reviews of airlines servicing Missouri

Get insights into the airlines that provide service to Missouri. Read reviews, discover amenities, and learn about the overall travel experience offered by airlines. Use this information to make informed decisions when choosing an airline for your flight to Missouri. Reviews last updated January 6, 2026.
Read reviews from past customers who have flown Delta, United Airlines, and American Airlines from Sioux Falls to Missouri. Reviews also offer insight into each airline's entertainment options, comfort, food, crew/service, and boarding process.
Delta
7.9
Good
8,018 reviews

Food

7.2

Comfort

7.9

Overall

7.9

Entertainment

7.8

Boarding

8.1

Crew

8.5

Reviews

1 / 20
6.0
Good

Jim,Nov 2025

AVL - ATL

The exit row seats without a seat in front are great for leg room but don’t have a fold out entertainment console so you’re forced to use the screen several feet in front of you (there is, at least, a remote). Best to bring a tablet loaded with entertainment or a book.
Delta
7.9
Good
8,018 reviews
Delta
7.9
Good
8,018 reviews

Food

7.2

Comfort

7.9

Overall

7.9

Entertainment

7.8

Boarding

8.1

Crew

8.5

Reviews

1 / 20
6.0
Good

Jim,Nov 2025

AVL - ATL

The exit row seats without a seat in front are great for leg room but don’t have a fold out entertainment console so you’re forced to use the screen several feet in front of you (there is, at least, a remote). Best to bring a tablet loaded with entertainment or a book.
United Airlines
7.4
Good
9,132 reviews
Delta
7.9
Good
8,018 reviews

Food

7.2

Comfort

7.9

Overall

7.9

Entertainment

7.8

Boarding

8.1

Crew

8.5

Reviews

1 / 20
6.0
Good

Jim,Nov 2025

AVL - ATL

The exit row seats without a seat in front are great for leg room but don’t have a fold out entertainment console so you’re forced to use the screen several feet in front of you (there is, at least, a remote). Best to bring a tablet loaded with entertainment or a book.
American Airlines
7.2
Good
11,084 reviews
Delta
7.9
Good
8,018 reviews

Food

7.2

Comfort

7.9

Overall

7.9

Entertainment

7.8

Boarding

8.1

Crew

8.5

Reviews

1 / 20
6.0
Good

Jim,Nov 2025

AVL - ATL

The exit row seats without a seat in front are great for leg room but don’t have a fold out entertainment console so you’re forced to use the screen several feet in front of you (there is, at least, a remote). Best to bring a tablet loaded with entertainment or a book.

Related info for your journey

Find useful and relevant information for your journey from Sioux Falls to Missouri. Access travel guides, tips, and recommendations to enhance your travel experience. Get information about local attractions, weather, transportation options, and more.

  • What airport do you fly from for flights from Sioux Falls to Missouri?

    Most people fly from Sioux Falls Joe Foss Field (FSD) if they book a flight from Sioux Falls to Missouri. Sioux Falls Joe Foss Field is conveniently located just 2.6 mi from Sioux Falls’s city center.

  • How long is the flight from Sioux Falls to Missouri?

    A quick flight from Sioux Falls to Missouri can take about 4h 06m. American Airlines provides one of the quickest options available for as low as $249. There are 470 mi between Sioux Falls and Missouri. This flight may include one or multiple stops.

  • What are the most popular routes from Sioux Falls to Missouri?

    The most popular flight routes from Sioux Falls to Missouri are Sioux Falls Joe Foss Field - Lambert-St Louis, Sioux Falls Joe Foss Field - Kansas City and Sioux Falls Joe Foss Field - Springfield-Branson.

  • Can I find deals for flights from Sioux Falls to Missouri that include hotel bookings?

    Yes. In addition to deals on Sioux Falls to Missouri flights, Cheapflights offers vacation packages that include both flights and hotel.

  • How can I find direct flights from Sioux Falls to Missouri?

    After entering your origin and destination, apply the non-stop filter on the search result page to find direct flights from Sioux Falls to Missouri.

  • Can I find deals for business class flights from Sioux Falls to Missouri?

    Yes. Cheapflights offers flight deals from Sioux Falls to Missouri by cabin class. In addition to browsing deals, you can also filter by cabin class on the search results page after making a search.

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Top 3 airlines flying from Sioux Falls to Missouri

Discover the top 3 airlines that operate flights from Sioux Falls to Missouri. Compare their services, reliability, and customer satisfaction ratings to choose the airline that best suits your travel preferences and needs. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated January 6, 2026.
AirlineCheapestAverageFlexibilityOn-time
American AirlinesCheapest$198Average$372FlexibilityNo cancel feeOn-time71%
DeltaCheapest$228Average$328FlexibilityNo cancel feeOn-timeN/A
United AirlinesCheapest$268Average$314FlexibilityNo cancel feeOn-time69%

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