$133+ Cheap flights from Sioux Falls (FSD) to Missouri
This is the cheapest one-way flight price found by a Cheapflights user in the last 72 hours by searching for a flight departing on 3/16. Fares are subject to change and may not be available on all flights or dates of travel.
FSD — STL
Mar 30 — Apr 61
1 adult, Economy
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Find cheap flights from Sioux Falls to Missouri with Cheapflights
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Cheapest flights from Sioux Falls to MissouriExplore the most affordable flight options available from Sioux Falls to Missouri. Find the lowest fares from popular airlines and budget airlines, with prices last updated on February 28, 2026.
Explore the most affordable flight options available from Sioux Falls to Missouri. Find the lowest fares from popular airlines and budget airlines, with prices last updated on February 28, 2026.
This Delta deal was found by Cheapflights users on 2/26. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 4/116:15 am
FSD
- STL
1 stop5h 33m
Delta
Wed 4/156:19 am
STL
- FSD
1 stop3h 53m
Delta
Deal found 2/26![Delta logo]()
$249
This Delta deal was found by Cheapflights users on 2/27. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 3/135:00 am
FSD
- MCI
1 stop3h 41m
Delta
Wed 3/185:40 pm
MCI
- FSD
1 stop5h 24m
Delta
Deal found 2/27![Delta logo]()
$259
This American Airlines deal was found by Cheapflights users on 2/27. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 5/87:39 pm
FSD
- STL
1 stop4h 17m
American Airlines
Sun 5/105:20 am
STL
- FSD
1 stop7h 36m
American Airlines
Deal found 2/27![American Airlines logo]()
$274
This Delta deal was found by Cheapflights users on 2/26. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 3/204:23 pm
FSD
- MCI
1 stop6h 40m
Delta
Tue 3/245:40 pm
MCI
- FSD
1 stop5h 24m
Delta
Deal found 2/26![Delta logo]()
$274
This Delta deal was found by Cheapflights users on 2/28. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 3/135:00 am
FSD
- MCI
1 stop3h 41m
Delta
Tue 3/175:40 pm
MCI
- FSD
1 stop5h 24m
Delta
Deal found 2/28![Delta logo]()
$279
This American Airlines deal was found by Cheapflights users on 2/26. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 3/267:42 pm
FSD
- STL
1 stop4h 02m
American Airlines
Thu 4/25:12 am
STL
- FSD
1 stop7h 29m
American Airlines
Deal found 2/26![American Airlines logo]()
$294
This United Airlines deal was found by Cheapflights users on 2/26. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 8/129:14 am
FSD
- STL
1 stop7h 17m
United Airlines
Sat 8/151:36 pm
STL
- FSD
1 stop6h 28m
United Airlines
Deal found 2/26![United Airlines logo]()
$309
This Delta deal was found by Cheapflights users on 2/26. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 3/204:23 pm
FSD
- MCI
1 stop6h 40m
Delta
Mon 3/235:40 pm
MCI
- FSD
1 stop5h 24m
Delta
Deal found 2/26![Delta logo]()
$319
This United Airlines deal was found by Cheapflights users on 2/25. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 2/277:40 am
FSD
- MCI
1 stop6h 44m
United Airlines
Sun 3/13:22 pm
MCI
- FSD
1 stop6h 35m
United Airlines
Deal found 2/25![United Airlines logo]()
$320
This Delta deal was found by Cheapflights users on 2/26. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 4/125:00 am
FSD
- STL
1 stop4h 01m
Delta
Wed 4/156:19 am
STL
- FSD
1 stop6h 44m
Delta
Deal found 2/26![Delta logo]()
$324
This American Airlines deal was found by Cheapflights users on 2/28. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 4/167:39 pm
FSD
- STL
1 stop4h 07m
American Airlines
Sun 4/195:51 am
STL
- FSD
1 stop6h 08m
American Airlines
Deal found 2/28![American Airlines logo]()
$344
This American Airlines deal was found by Cheapflights users on 2/26. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 4/127:39 pm
FSD
- STL
1 stop4h 07m
American Airlines
Fri 4/178:03 pm
STL
- FSD
1 stop15h 56m
American Airlines
Deal found 2/26![American Airlines logo]()
$356
Best flights from Sioux Falls to MissouriDiscover carefully curated flight deals from Sioux Falls to Missouri that have cost, travel time, and layovers in mind to ensure you get the best travel experience. Data last updated February 28, 2026.
Discover carefully curated flight deals from Sioux Falls to Missouri that have cost, travel time, and layovers in mind to ensure you get the best travel experience. Data last updated February 28, 2026.
This Delta deal was found by Cheapflights users on 2/25. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 5/169:15 am
FSD
- STL
1 stop6h 04m
Delta
Wed 5/206:21 am
STL
- FSD
1 stop6h 28m
Delta
Deal found 2/25![Delta logo]()
$249
This American Airlines deal was found by Cheapflights users on 2/26. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 3/267:42 pm
FSD
- STL
1 stop4h 02m
American Airlines
Thu 4/25:12 am
STL
- FSD
1 stop7h 29m
American Airlines
Deal found 2/26![American Airlines logo]()
$294
This United Airlines deal was found by Cheapflights users on 2/26. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 8/129:14 am
FSD
- STL
1 stop7h 17m
United Airlines
Sat 8/151:36 pm
STL
- FSD
1 stop6h 28m
United Airlines
Deal found 2/26![United Airlines logo]()
$309
This Delta deal was found by Cheapflights users on 2/26. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 4/116:15 am
FSD
- STL
1 stop5h 33m
Delta
Wed 4/156:19 am
STL
- FSD
1 stop3h 53m
Delta
Deal found 2/26![Delta logo]()
$249
This Kiwi.com deal was found by Cheapflights users on 2/26. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 3/138:54 pm
FSD
- STL
1 stop12h 55m
Frontier
Sun 3/158:06 pm
STL
- FSD
2 stops23h 53m
Frontier
Deal found 2/26![Frontier logo]()
$524
This Kiwi.com deal was found by Cheapflights users on 2/28. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 3/138:54 pm
FSD
- MCI
1 stop23h 01m
Multiple Airlines
Wed 3/1812:24 pm
MCI
- FSD
2 stops50h 06m
Multiple Airlines
Deal found 2/28![Multiple Airlines logo]()
$546
This Delta deal was found by Cheapflights users on 2/26. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 3/204:23 pm
FSD
- MCI
1 stop6h 40m
Delta
Tue 3/245:40 pm
MCI
- FSD
1 stop5h 24m
Delta
Deal found 2/26![Delta logo]()
$274
This United Airlines deal was found by Cheapflights users on 2/26. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 4/34:57 pm
FSD
- MCI
1 stop6h 29m
United Airlines
Mon 4/63:21 pm
MCI
- FSD
1 stop6h 28m
United Airlines
Deal found 2/26![United Airlines logo]()
$320
This American Airlines deal was found by Cheapflights users on 2/26. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 4/127:39 pm
FSD
- STL
1 stop4h 07m
American Airlines
Fri 4/178:03 pm
STL
- FSD
1 stop15h 56m
American Airlines
Deal found 2/26![American Airlines logo]()
$356
This Delta deal was found by Cheapflights users on 2/26. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 4/125:00 am
FSD
- STL
1 stop4h 01m
Delta
Wed 4/156:19 am
STL
- FSD
1 stop6h 44m
Delta
Deal found 2/26![Delta logo]()
$324
This United Airlines deal was found by Cheapflights users on 2/26. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 3/1411:21 am
FSD
- STL
1 stop5h 02m
United Airlines
Wed 3/182:50 pm
STL
- FSD
1 stop5h 50m
United Airlines
Deal found 2/26![United Airlines logo]()
$388
This United Airlines deal was found by Cheapflights users on 2/25. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 3/127:43 am
FSD
- MCI
1 stop4h 36m
United Airlines
Mon 3/163:22 pm
MCI
- FSD
1 stop6h 40m
United Airlines
Deal found 2/25![United Airlines logo]()
$448
This Kiwi.com deal was found by Cheapflights users on 2/28. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 3/138:54 pm
FSD
- MCI
1 stop23h 01m
Multiple Airlines
Tue 3/176:04 pm
MCI
- FSD
2 stops41h 35m
Multiple Airlines
Deal found 2/28![Multiple Airlines logo]()
$639
This American Airlines deal was found by Cheapflights users on 2/26. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 3/137:42 pm
FSD
- STL
1 stop3h 53m
American Airlines
Sun 3/155:12 am
STL
- FSD
1 stop7h 29m
American Airlines
Deal found 2/26![American Airlines logo]()
$619
This Delta deal was found by Cheapflights users on 2/26. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 3/1111:01 am
FSD
- MCI
1 stop4h 03m
Delta
Sat 3/145:39 pm
MCI
- FSD
1 stop5h 25m
Delta
Deal found 2/26![Delta logo]()
$607
This United Airlines deal was found by Cheapflights users on 2/27. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 3/143:10 pm
FSD
- SGF
1 stop6h 49m
United Airlines
Wed 3/187:45 am
SGF
- FSD
2 stops12h 55m
United Airlines
Deal found 2/27![United Airlines logo]()
$619
This United Airlines deal was found by Cheapflights users on 2/27. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 3/129:00 am
FSD
- MCI
1 stop7h 19m
United Airlines
Sun 3/155:00 pm
MCI
- FSD
1 stop5h 02m
United Airlines
Deal found 2/27![United Airlines logo]()
$674
This Delta deal was found by Cheapflights users on 2/27. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 3/158:00 am
FSD
- MCI
1 stop3h 37m
Delta
Thu 3/196:35 am
MCI
- FSD
2 stops9h 07m
Delta
Deal found 2/27![Delta logo]()
$701
This United Airlines deal was found by Cheapflights users on 2/26. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 3/137:43 am
FSD
- MCI
1 stop6h 37m
United Airlines
Tue 3/179:15 am
MCI
- FSD
2 stops11h 25m
United Airlines
Deal found 2/26![United Airlines logo]()
$707
This United Airlines deal was found by Cheapflights users on 2/26. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 3/135:10 pm
FSD
- SGF
2 stops21h 28m
United Airlines
Tue 3/173:10 pm
SGF
- FSD
1 stop6h 52m
United Airlines
Deal found 2/26![United Airlines logo]()
$781
This Delta deal was found by Cheapflights users on 2/27. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 3/135:00 am
FSD
- MCI
2 stops8h 30m
Delta
Tue 3/1712:17 pm
MCI
- FSD
1 stop3h 25m
Delta
Deal found 2/27![Delta logo]()
$914
This United Airlines deal was found by Cheapflights users on 2/25. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 3/127:43 am
FSD
- STL
1 stop6h 59m
United Airlines
Mon 3/163:23 pm
STL
- FSD
2 stops8h 21m
United Airlines
Deal found 2/25![United Airlines logo]()
$976
This United Airlines deal was found by Cheapflights users on 2/27. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 3/125:10 pm
FSD
- MCI
1 stop6h 05m
United Airlines
Sat 3/149:15 am
MCI
- FSD
1 stop5h 17m
United Airlines
Deal found 2/27![United Airlines logo]()
$1,025
Last-minute flights from Sioux Falls to MissouriDiscover last-minute flight deals from Sioux Falls to Missouri. Data last updated February 28, 2026 and is based on user searches.
Discover last-minute flight deals from Sioux Falls to Missouri. Data last updated February 28, 2026 and is based on user searches.
This United Airlines deal was found by Cheapflights users on 2/24. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 2/265:00 pm
FSD
- MCI
1 stop6h 17m
United Airlines
Sat 2/285:54 am
MCI
- FSD
1 stop7h 01m
United Airlines
Deal found 2/24![United Airlines logo]()
$379
This United Airlines deal was found by Cheapflights users on 2/25. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 2/277:40 am
FSD
- MCI
1 stop6h 44m
United Airlines
Sun 3/13:22 pm
MCI
- FSD
1 stop6h 35m
United Airlines
Deal found 2/25![United Airlines logo]()
$320
This Delta deal was found by Cheapflights users on 2/25. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 2/271:00 pm
FSD
- MCI
2 stops8h 07m
Delta
Sun 3/16:23 am
MCI
- FSD
1 stop3h 45m
Delta
Deal found 2/25![Delta logo]()
$437
This United Airlines deal was found by Cheapflights users on 2/24. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 2/287:40 am
FSD
- STL
1 stop6h 49m
United Airlines
Wed 3/46:00 pm
STL
- FSD
1 stop5h 44m
United Airlines
Deal found 2/24![United Airlines logo]()
$369
This United Airlines deal was found by Cheapflights users on 2/25. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 3/129:00 am
FSD
- STL
1 stop7h 56m
United Airlines
Mon 3/165:55 pm
STL
- FSD
1 stop5h 49m
United Airlines
Deal found 2/25![United Airlines logo]()
$388
This United Airlines deal was found by Cheapflights users on 2/25. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 3/127:43 am
FSD
- MCI
1 stop4h 36m
United Airlines
Mon 3/163:22 pm
MCI
- FSD
1 stop6h 40m
United Airlines
Deal found 2/25![United Airlines logo]()
$448
This Delta deal was found by Cheapflights users on 2/27. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 3/135:00 am
FSD
- MCI
1 stop3h 41m
Delta
Wed 3/185:40 pm
MCI
- FSD
1 stop5h 24m
Delta
Deal found 2/27![Delta logo]()
$259
This Delta deal was found by Cheapflights users on 2/28. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 3/135:00 am
FSD
- MCI
1 stop3h 41m
Delta
Tue 3/175:40 pm
MCI
- FSD
1 stop5h 24m
Delta
Deal found 2/28![Delta logo]()
$279
This United Airlines deal was found by Cheapflights users on 2/26. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 3/135:10 pm
FSD
- MCI
1 stop6h 05m
United Airlines
Tue 3/173:22 pm
MCI
- FSD
1 stop6h 40m
United Airlines
Deal found 2/26![United Airlines logo]()
$440
This Delta deal was found by Cheapflights users on 2/26. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 3/204:23 pm
FSD
- MCI
1 stop6h 40m
Delta
Tue 3/245:40 pm
MCI
- FSD
1 stop5h 24m
Delta
Deal found 2/26![Delta logo]()
$274
This Delta deal was found by Cheapflights users on 2/26. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 3/204:23 pm
FSD
- MCI
1 stop6h 40m
Delta
Mon 3/235:40 pm
MCI
- FSD
1 stop5h 24m
Delta
Deal found 2/26![Delta logo]()
$319
This American Airlines deal was found by Cheapflights users on 2/26. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 3/267:42 pm
FSD
- STL
1 stop4h 02m
American Airlines
Thu 4/25:12 am
STL
- FSD
1 stop7h 29m
American Airlines
Deal found 2/26![American Airlines logo]()
$294
One-way flights from Sioux Falls to MissouriSearch for one-way flight options from Sioux Falls to Missouri. Find affordable one-way fares based on user searches. Data last updated February 28, 2026.
Search for one-way flight options from Sioux Falls to Missouri. Find affordable one-way fares based on user searches. Data last updated February 28, 2026.
This Kiwi.com deal was found by Cheapflights users on 2/26. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 3/165:55 pm
FSD
- STL
2 stops40h 42m
Multiple Airlines
Deal found 2/26![Multiple Airlines logo]()
$133
This Kiwi.com deal was found by Cheapflights users on 2/26. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 3/1711:01 am
FSD
- STL
2 stops23h 36m
Multiple Airlines
Deal found 2/26![Multiple Airlines logo]()
$189
This American Airlines deal was found by Cheapflights users on 2/26. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 4/126:47 am
FSD
- STL
1 stop5h 00m
American Airlines
Deal found 2/26![American Airlines logo]()
$199
This United Airlines deal was found by Cheapflights users on 2/26. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 3/147:43 am
FSD
- STL
1 stop7h 00m
United Airlines
Deal found 2/26![United Airlines logo]()
$229
This Kiwi.com deal was found by Cheapflights users on 2/27. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 3/138:54 pm
FSD
- MCI
1 stop23h 01m
Frontier
Deal found 2/27![Frontier logo]()
$235
This Delta deal was found by Cheapflights users on 2/27. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 5/285:00 am
FSD
- STL
1 stop5h 32m
Delta
Deal found 2/27![Delta logo]()
$238
This Delta deal was found by Cheapflights users on 2/26. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 3/125:00 am
FSD
- STL
1 stop4h 01m
Delta
Deal found 2/26![Delta logo]()
$239
This United Airlines deal was found by Cheapflights users on 2/27. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 3/137:43 am
FSD
- MCI
1 stop6h 37m
United Airlines
Deal found 2/27![United Airlines logo]()
$239
This Kiwi.com deal was found by Cheapflights users on 2/25. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 3/279:22 pm
FSD
- SGF
1 stop23h 37m
Allegiant Air
Deal found 2/25![Allegiant Air logo]()
$250
This Kiwi.com deal was found by Cheapflights users on 2/26. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 4/1210:25 am
FSD
- STL
3 stops32h 11m
Multiple Airlines
Deal found 2/26![Multiple Airlines logo]()
$285
This Kiwi.com deal was found by Cheapflights users on 2/27. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 3/68:54 pm
FSD
- SGF
2 stops38h 50m
Multiple Airlines
Deal found 2/27![Multiple Airlines logo]()
$329
This American Airlines deal was found by Cheapflights users on 2/27. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 3/61:26 pm
FSD
- SGF
1 stop5h 50m
American Airlines
Deal found 2/27![American Airlines logo]()
$337
Find flight deals from Sioux Falls to Missouri
Keep the following information in mind while searching for Sioux Falls to Missouri flight deals. Data was last updated February 28, 2026.
Most accurate provider | FlightHub 3 stars |
|---|---|
Most trusted provider | FlightHub 3 stars |
Round-trip from | $249 (Delta) |
One-way from | $133 (Kiwi.com) |
Popular in | March |
Cheapest in | September |
Average price | $308 |
Cheapflights Fare Finder
Customize your flight search to find flights from Sioux Falls to Missouri that fit within your specific budget. Explore options based on user searches and filter the results based on your desired price range. Find flights that match your budget for a cost-effective journey. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated February 28, 2026.
Use the filters below to find and compare flights from Sioux Falls to Missouri that are best for you.
Fly from
Fly to
Route
Depart
Return
Sioux FallsSt. Louis
FSD - STL
FSDSTL
Sioux Falls Joe Foss Field
Sat 5/16
9:15 am-3:19 pm
1 stop6h 04m
Lambert-St Louis
Wed 5/20
6:21 am-12:49 pm
1 stop6h 28m
$249
Sioux FallsSt. Louis
FSD - STL
FSDSTL
Sioux Falls Joe Foss Field
Sat 4/11
6:15 am-11:48 am
1 stop5h 33m
Lambert-St Louis
Wed 4/15
6:19 am-10:12 am
1 stop3h 53m
$249
Sioux FallsKansas City
FSD - MCI
FSDMCI
Sioux Falls Joe Foss Field
Fri 3/20
4:23 pm-11:03 pm
1 stop6h 40m
Kansas City
Tue 3/24
5:40 pm-11:04 pm
1 stop5h 24m
$274
Sioux FallsSt. Louis
FSD - STL
FSDSTL
Sioux Falls Joe Foss Field
Thu 3/26
7:42 pm-11:44 pm
1 stop4h 02m
Lambert-St Louis
Thu 4/2
5:12 am-12:41 pm
1 stop7h 29m
$294
Sioux FallsSt. Louis
FSD - STL
FSDSTL
Sioux Falls Joe Foss Field
Wed 8/12
9:14 am-4:31 pm
1 stop7h 17m
Lambert-St Louis
Sat 8/15
1:36 pm-8:04 pm
1 stop6h 28m
$309
Sioux FallsKansas City
FSD - MCI
FSDMCI
Sioux Falls Joe Foss Field
Fri 4/3
4:57 pm-11:26 pm
1 stop6h 29m
Kansas City
Mon 4/6
3:21 pm-9:49 pm
1 stop6h 28m
$320
Sioux FallsSt. Louis
FSD - STL
FSDSTL
Sioux Falls Joe Foss Field
Sun 4/12
5:00 am-9:01 am
1 stop4h 01m
Lambert-St Louis
Wed 4/15
6:19 am-1:03 pm
1 stop6h 44m
$324
Sioux FallsSt. Louis
FSD - STL
FSDSTL
Sioux Falls Joe Foss Field
Sun 4/12
7:39 pm-11:46 pm
1 stop4h 07m
Lambert-St Louis
Fri 4/17
8:03 pm-11:59 am
1 stop15h 56m
$356
Sioux FallsSt. Louis
FSD - STL
FSDSTL
Sioux Falls Joe Foss Field
Sat 3/14
11:21 am-4:23 pm
1 stop5h 02m
Lambert-St Louis
Wed 3/18
2:50 pm-8:40 pm
1 stop5h 50m
$388
Sioux FallsKansas City
FSD - MCI
FSDMCI
Sioux Falls Joe Foss Field
Thu 3/12
7:43 am-12:19 pm
1 stop4h 36m
Kansas City
Mon 3/16
3:22 pm-10:02 pm
1 stop6h 40m
$448
Showing 1-10 of 41 resultsSorted by cheapest first
Best time to book a flight from Sioux Falls to Missouri
Have a flexible travel schedule? Discover the best time to fly to Missouri from Sioux Falls with our price prediction graph.
FSD-STL
FSD-MCI
FSD-SGF
Estimated round-trip price
Rates are based on past data. Find the cheapest month and day to book your flight based on your travel requirements, then search for cheap deals.
Cheapflights Insights
Everything you need to know about your flight from Sioux Falls to Missouri
FSD-USMO
FSD-STL
FSD-MCI
FSD-SGF
What is the cheapest month to book a flight from Sioux Falls to Missouri?
Currently, April is the cheapest month in which you can book a flight from Sioux Falls to Missouri (average of $228). Flying from Sioux Falls to Missouri in November is currently the most expensive (average of $318). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.
How much does it cost to fly round-trip from Sioux Falls to Missouri?
Reviews of airlines servicing Missouri
Get insights into the airlines that provide service to Missouri. Read reviews, discover amenities, and learn about the overall travel experience offered by airlines. Use this information to make informed decisions when choosing an airline for your flight to Missouri. Reviews last updated February 28, 2026.
Read reviews from past customers who have flown Delta, United Airlines, and American Airlines from Sioux Falls to Missouri. Reviews also offer insight into each airline's entertainment options, comfort, food, crew/service, and boarding process.
Overall
7.9
Comfort
7.9
Boarding
8.1
Crew
8.5
Food
7.2
Entertainment
7.8
Reviews
1 / 20
6.0
GoodJim,Nov 2025
AVL - ATL
Overall
7.9
Comfort
7.9
Boarding
8.1
Crew
8.5
Food
7.2
Entertainment
7.8
Reviews
1 / 20
6.0
GoodJim,Nov 2025
AVL - ATL
Overall
7.9
Comfort
7.9
Boarding
8.1
Crew
8.5
Food
7.2
Entertainment
7.8
Reviews
1 / 20
6.0
GoodJim,Nov 2025
AVL - ATL
Overall
7.9
Comfort
7.9
Boarding
8.1
Crew
8.5
Food
7.2
Entertainment
7.8
Reviews
1 / 20
6.0
GoodJim,Nov 2025
AVL - ATL
Related info for your journey
Find useful and relevant information for your journey from Sioux Falls to Missouri. Access travel guides, tips, and recommendations to enhance your travel experience. Get information about local attractions, weather, transportation options, and more.
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Alternative routes for Sioux Falls to Missouri
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Complete your trip
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Sioux Falls and Missouri flights
Browse other Sioux Falls and Missouri flight options. Last updated on February 28, 2026.
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Sioux Falls to Missouri flights
Consider these flights traveling from Sioux Falls to Missouri.
Top 3 airlines flying from Sioux Falls to Missouri
Discover the top 3 airlines that operate flights from Sioux Falls to Missouri. Compare their services, reliability, and customer satisfaction ratings to choose the airline that best suits your travel preferences and needs. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated February 28, 2026.
| Airline | Cheapest | Average | Flexibility | On-time |
|---|---|---|---|---|
| Cheapest$198 | Average$386 | FlexibilityNo cancel fee | On-time71% | |
| Cheapest$228 | Average$343 | FlexibilityNo cancel fee | On-timeN/A | |
| Cheapest$268 | Average$309 | FlexibilityNo cancel fee | On-time69% |