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$181+ Cheap flights from Sioux Falls (FSD) to Missouri

This is the cheapest round-trip flight price found by a Cheapflights user in the last 72 hours by searching for a flight departing on 2/12. Fares are subject to change and may not be available on all flights or dates of travel.
FSD — STL
feb. 14 — feb. 211
sáb. 2/14
sáb. 2/21
1 adult, Economy
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Cheap flight deals from Sioux Falls to Missouri

Keep the following information in mind while searching for Sioux Falls to Missouri flight deals. Data was last updated enero 15, 2026.

Most accurate provider

eDreams
3 stars

Most trusted provider

eDreams
3 stars

Round-trip from

$181
(Frontier)

Popular in

March

Cheapest in

January

Average price

$249
Provider with most accurate pricing for Sioux Falls Joe Foss Field-Lambert-St Louis flight deals.
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Provider most trusted by Cheapflights users for Sioux Falls Joe Foss Field-Lambert-St Louis flights.
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From Sioux Falls Joe Foss Field to Missouri
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Highest demand for flights based on searches. 0% potential increase in price ($3 potential increase over avg. RT price).
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Cheapest flight prices on average. 3% potential price decrease ($11 potential savings vs. average RT price).
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Average for round-trip flights in January 2026
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Find flight deals from Sioux Falls to Missouri

Cheapest flights from Sioux Falls to Missouri
Explore the most affordable flight options available from Sioux Falls to Missouri. Find the lowest fares from popular airlines and budget airlines, with prices last updated on enero 15, 2026.

This Frontier deal was found by Cheapflights users on 1/14. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Frontier is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
jue. 2/122:16 pm
FSD
-
STL
1 stop22h 53m
Frontier
mié. 2/184:51 pm
STL
-
FSD
1 stop20h 30m
Frontier
Deal found 1/14$181
This Delta deal was found by Cheapflights users on 1/14. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
jue. 2/1910:55 am
FSD
-
STL
1 stop3h 59m
Delta
dom. 2/226:10 am
STL
-
FSD
1 stop3h 58m
Delta
Deal found 1/14$249
This American Airlines deal was found by Cheapflights users on 1/14. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
jue. 1/295:35 pm
FSD
-
MCI
1 stop5h 37m
American Airlines
lun. 2/24:37 pm
MCI
-
FSD
1 stop4h 58m
American Airlines
Deal found 1/14$259
This Kiwi.com deal was found by Cheapflights users on 1/13. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
vie. 2/131:41 pm
FSD
-
STL
1 stop24h 15m
Multiple Airlines
vie. 2/209:50 am
STL
-
FSD
2 stops8h 22m
Multiple Airlines
Deal found 1/13$264
This Delta deal was found by Cheapflights users on 1/14. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
mar. 1/275:00 am
FSD
-
STL
1 stop5h 43m
Delta
sáb. 1/3111:23 am
STL
-
FSD
1 stop4h 14m
Delta
Deal found 1/14$279
This American Airlines deal was found by Cheapflights users on 1/14. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
vie. 2/65:35 pm
FSD
-
SGF
1 stop5h 12m
American Airlines
dom. 2/84:59 pm
SGF
-
FSD
1 stop4h 36m
American Airlines
Deal found 1/14$284
This Delta deal was found by Cheapflights users on 1/14. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
mié. 3/1811:01 am
FSD
-
STL
1 stop6h 04m
Delta
lun. 3/235:25 pm
STL
-
FSD
1 stop5h 34m
Delta
Deal found 1/14$288
This United Airlines deal was found by Cheapflights users on 1/14. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
mié. 2/117:30 am
FSD
-
SGF
1 stop7h 08m
United Airlines
dom. 2/151:25 pm
SGF
-
FSD
1 stop7h 14m
United Airlines
Deal found 1/14$293
This United Airlines deal was found by Cheapflights users on 1/15. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
sáb. 1/2411:22 am
FSD
-
STL
1 stop4h 41m
United Airlines
mar. 1/271:15 pm
STL
-
FSD
1 stop4h 03m
United Airlines
Deal found 1/15$299
This United Airlines deal was found by Cheapflights users on 1/13. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
jue. 1/227:30 am
FSD
-
SGF
1 stop7h 08m
United Airlines
dom. 1/255:03 pm
SGF
-
FSD
1 stop6h 41m
United Airlines
Deal found 1/13$299
This Delta deal was found by Cheapflights users on 1/13. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
sáb. 1/176:25 am
FSD
-
STL
1 stop4h 16m
Delta
mar. 1/205:25 pm
STL
-
FSD
1 stop5h 39m
Delta
Deal found 1/13$309
This American Airlines deal was found by Cheapflights users on 1/14. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
vie. 2/65:35 pm
FSD
-
SGF
1 stop5h 12m
American Airlines
lun. 2/94:59 pm
SGF
-
FSD
1 stop4h 36m
American Airlines
Deal found 1/14$319

Cheapflights Fare Finder

 
Customize your flight search to find flights from Sioux Falls to Missouri that fit within your specific budget. Explore options based on user searches and filter the results based on your desired price range. Find flights that match your budget for a cost-effective journey. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated enero 15, 2026.
Use the filters below to find and compare flights from Sioux Falls to Missouri that are best for you.

Fly from

Sioux Falls

Fly to

Missouri

Route

Depart

Return

Price

Sioux FallsSt. Louis

FSD - STL

FSDSTL

Sioux Falls Joe Foss Field

jue. 2/12

2:16 pm-1:09 pm

1 stop22h 53m

Lambert-St Louis

mié. 2/18

4:51 pm-1:21 pm

1 stop20h 30m

$181

Sioux FallsSt. Louis

FSD - STL

FSDSTL

Sioux Falls Joe Foss Field

mié. 3/25

5:21 pm-10:58 pm

1 stop5h 37m

Lambert-St Louis

mar. 3/31

5:12 am-12:37 pm

1 stop7h 25m

$249

Sioux FallsSt. Louis

FSD - STL

FSDSTL

Sioux Falls Joe Foss Field

vie. 2/13

10:55 am-4:45 pm

1 stop5h 50m

Lambert-St Louis

vie. 2/20

6:10 am-10:08 am

1 stop3h 58m

$249

Sioux FallsSt. Louis

FSD - STL

FSDSTL

Sioux Falls Joe Foss Field

jue. 2/12

7:42 pm-11:48 pm

1 stop4h 06m

Lambert-St Louis

jue. 2/19

8:00 am-1:36 pm

1 stop5h 36m

$249

Sioux FallsSt. Louis

FSD - STL

FSDSTL

Sioux Falls Joe Foss Field

jue. 2/19

10:55 am-2:54 pm

1 stop3h 59m

Lambert-St Louis

sáb. 2/21

6:10 am-12:20 pm

1 stop6h 10m

$249

Sioux FallsSt. Louis

FSD - STL

FSDSTL

Sioux Falls Joe Foss Field

jue. 3/5

2:08 pm-9:12 pm

1 stop7h 04m

Lambert-St Louis

sáb. 3/7

5:12 am-12:42 pm

1 stop7h 30m

$249

Sioux FallsSt. Louis

FSD - STL

FSDSTL

Sioux Falls Joe Foss Field

jue. 2/19

10:55 am-2:54 pm

1 stop3h 59m

Lambert-St Louis

dom. 2/22

6:10 am-10:08 am

1 stop3h 58m

$249

Sioux FallsSt. Louis

FSD - STL

FSDSTL

Sioux Falls Joe Foss Field

sáb. 3/14

1:34 pm-5:08 pm

1 stop3h 34m

Lambert-St Louis

vie. 3/20

5:25 pm-10:59 pm

1 stop5h 34m

$249

Sioux FallsSt. Louis

FSD - STL

FSDSTL

Sioux Falls Joe Foss Field

mar. 2/17

7:42 pm-11:48 pm

1 stop4h 06m

Lambert-St Louis

mar. 2/24

4:13 pm-9:40 pm

1 stop5h 27m

$249

Sioux FallsSt. Louis

FSD - STL

FSDSTL

Sioux Falls Joe Foss Field

mar. 1/27

5:00 am-10:43 am

1 stop5h 43m

Lambert-St Louis

sáb. 1/31

11:23 am-3:37 pm

1 stop4h 14m

$279

Flights are sorted by cheapest round-trip flights first.

Deals found on 1/14

Showing 1-10 of 40 results
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Best time to book a flight from Sioux Falls to Missouri

Have a flexible travel schedule? Discover the best time to fly to Missouri from Sioux Falls with our price prediction graph.
Estimated round-trip price
Rates are based on past data. Find the cheapest month and day to book your flight based on your travel requirements, then search for cheap deals.

Cheapflights Insights

Everything you need to know about your flight from Sioux Falls to Missouri

What is the cheapest month to book a flight from Sioux Falls to Missouri?

Currently, February is the cheapest month in which you can book a flight from Sioux Falls to Missouri (average of $205). Flying from Sioux Falls to Missouri in November is currently the most expensive (average of $318). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.

Reviews of airlines servicing Missouri

Get insights into the airlines that provide service to Missouri. Read reviews, discover amenities, and learn about the overall travel experience offered by airlines. Use this information to make informed decisions when choosing an airline for your flight to Missouri. Reviews last updated enero 15, 2026.
Read reviews from past customers who have flown Delta, United Airlines, and American Airlines from Sioux Falls to Missouri. Reviews also offer insight into each airline's entertainment options, comfort, food, crew/service, and boarding process.
Delta
7.9
Good
8,051 reviews

Boarding

8.1

Crew

8.5

Food

7.2

Entertainment

7.8

Comfort

7.9

Overall

7.9

Reviews

1 / 20
6.0
Good

Jim,Nov 2025

AVL - ATL

The exit row seats without a seat in front are great for leg room but don’t have a fold out entertainment console so you’re forced to use the screen several feet in front of you (there is, at least, a remote). Best to bring a tablet loaded with entertainment or a book.
Delta
7.9
Good
8,051 reviews
Delta
7.9
Good
8,051 reviews

Boarding

8.1

Crew

8.5

Food

7.2

Entertainment

7.8

Comfort

7.9

Overall

7.9

Reviews

1 / 20
6.0
Good

Jim,Nov 2025

AVL - ATL

The exit row seats without a seat in front are great for leg room but don’t have a fold out entertainment console so you’re forced to use the screen several feet in front of you (there is, at least, a remote). Best to bring a tablet loaded with entertainment or a book.
United Airlines
7.4
Good
9,164 reviews
Delta
7.9
Good
8,051 reviews

Boarding

8.1

Crew

8.5

Food

7.2

Entertainment

7.8

Comfort

7.9

Overall

7.9

Reviews

1 / 20
6.0
Good

Jim,Nov 2025

AVL - ATL

The exit row seats without a seat in front are great for leg room but don’t have a fold out entertainment console so you’re forced to use the screen several feet in front of you (there is, at least, a remote). Best to bring a tablet loaded with entertainment or a book.
American Airlines
7.2
Good
11,136 reviews
Delta
7.9
Good
8,051 reviews

Boarding

8.1

Crew

8.5

Food

7.2

Entertainment

7.8

Comfort

7.9

Overall

7.9

Reviews

1 / 20
6.0
Good

Jim,Nov 2025

AVL - ATL

The exit row seats without a seat in front are great for leg room but don’t have a fold out entertainment console so you’re forced to use the screen several feet in front of you (there is, at least, a remote). Best to bring a tablet loaded with entertainment or a book.

Related info for your journey

Find useful and relevant information for your journey from Sioux Falls to Missouri. Access travel guides, tips, and recommendations to enhance your travel experience. Get information about local attractions, weather, transportation options, and more.

  • What airport do you fly from for flights from Sioux Falls to Missouri?

    Most people fly from Sioux Falls Joe Foss Field (FSD) if they book a flight from Sioux Falls to Missouri. Sioux Falls Joe Foss Field is conveniently located just 2.6 mi from Sioux Falls’s city center.

  • How long is the flight from Sioux Falls to Missouri?

    A quick flight from Sioux Falls to Missouri can take about 5h 37m. Frontier provides one of the quickest options available for as low as $249. There are 470 mi between Sioux Falls and Missouri. This flight may include one or multiple stops.

  • What are the most popular routes from Sioux Falls to Missouri?

    The most popular flight routes from Sioux Falls to Missouri are Sioux Falls Joe Foss Field - Lambert-St Louis, Sioux Falls Joe Foss Field - Springfield-Branson and Sioux Falls Joe Foss Field - Kansas City.

  • Can I find deals for flights from Sioux Falls to Missouri that include hotel bookings?

    Yes. In addition to deals on Sioux Falls to Missouri flights, Cheapflights offers vacation packages that include both flights and hotel.

  • How can I find direct flights from Sioux Falls to Missouri?

    After entering your origin and destination, apply the non-stop filter on the search result page to find direct flights from Sioux Falls to Missouri.

  • Can I find deals for business class flights from Sioux Falls to Missouri?

    Yes. Cheapflights offers flight deals from Sioux Falls to Missouri by cabin class. In addition to browsing deals, you can also filter by cabin class on the search results page after making a search.

  • What is the cheapest month to book a flight from Sioux Falls to Missouri?

    Currently, February is the cheapest month in which you can book a flight from Sioux Falls to Missouri (average of $205). Flying from Sioux Falls to Missouri in November is currently the most expensive (average of $318). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.

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Top 3 airlines flying from Sioux Falls to Missouri

Discover the top 3 airlines that operate flights from Sioux Falls to Missouri. Compare their services, reliability, and customer satisfaction ratings to choose the airline that best suits your travel preferences and needs. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated enero 15, 2026.
AirlineCheapestAverageFlexibilityOn-time
American AirlinesCheapest$198Average$372FlexibilityNo cancel feeOn-time71%
DeltaCheapest$228Average$328FlexibilityNo cancel feeOn-timeN/A
United AirlinesCheapest$268Average$314FlexibilityNo cancel feeOn-time69%

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