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$379+ Cheap flights from Portugal to Missouri

This is the cheapest one-way flight price found by a Cheapflights user in the last 72 hours by searching for a flight departing on 4/22. Fares are subject to change and may not be available on all flights or dates of travel.
LIS — STL
Apr 21 — Apr 281
Tue 4/21
Tue 4/28
1 adult, Economy
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Cheap flight deals from Portugal to Missouri

Cheapest flights from Portugal to Missouri
Explore the most affordable flight options available from Portugal to Missouri. Find the lowest fares from popular airlines and budget airlines, with prices last updated on March 22, 2026.

This United Airlines deal was found by Cheapflights users on 3/17. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 4/112:00 pm
OPO
-
STL
2 stops17h 11m
United Airlines
Sun 4/59:10 am
STL
-
OPO
2 stops18h 35m
United Airlines
Deal found 3/17$895
This United Airlines deal was found by Cheapflights users on 3/17. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 11/126:00 am
OPO
-
STL
2 stops22h 54m
United Airlines
Mon 11/168:50 am
STL
-
OPO
2 stops18h 40m
United Airlines
Deal found 3/17$898
This Delta deal was found by Cheapflights users on 3/18. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 6/105:00 am
LIS
-
STL
2 stops17h 49m
Delta
Wed 6/242:18 pm
STL
-
LIS
2 stops18h 37m
Delta
Deal found 3/18$912
This British Airways deal was found by Cheapflights users on 3/17. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure British Airways is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 3/2511:05 am
LIS
-
STL
1 stop16h 57m
British Airways
Tue 4/218:03 pm
STL
-
LIS
2 stops15h 52m
British Airways
Deal found 3/17$917
This United Airlines deal was found by Cheapflights users on 3/17. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 4/307:25 am
LIS
-
STL
1 stop36h 00m
United Airlines
Mon 5/48:45 am
STL
-
LIS
1 stop19h 45m
United Airlines
Deal found 3/17$921
This American Airlines deal was found by Cheapflights users on 3/17. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 4/306:35 am
LIS
-
STL
2 stops21h 42m
American Airlines
Mon 5/45:21 pm
STL
-
LIS
2 stops18h 34m
American Airlines
Deal found 3/17$922
This United Airlines deal was found by Cheapflights users on 3/20. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 4/175:05 am
LIS
-
STL
1 stop14h 20m
United Airlines
Tue 4/216:15 am
STL
-
LIS
1 stop20h 05m
United Airlines
Deal found 3/20$923
This United Airlines deal was found by Cheapflights users on 3/17. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 3/2511:55 am
LIS
-
STL
2 stops27h 49m
United Airlines
Tue 4/219:10 am
STL
-
LIS
2 stops17h 10m
United Airlines
Deal found 3/17$930
This Booking.com deal was found by Cheapflights users on 3/20. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Booking.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 4/175:05 am
LIS
-
STL
1 stop14h 20m
Lufthansa
Tue 4/211:10 pm
STL
-
LIS
2 stops20h 25m
Lufthansa
Deal found 3/20$932
This United Airlines deal was found by Cheapflights users on 3/18. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 6/85:05 am
LIS
-
STL
1 stop14h 20m
United Airlines
Wed 6/241:15 pm
STL
-
LIS
1 stop14h 05m
United Airlines
Deal found 3/18$941
This United Airlines deal was found by Cheapflights users on 3/18. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 6/75:05 am
LIS
-
STL
2 stops16h 41m
United Airlines
Wed 6/241:15 pm
STL
-
LIS
1 stop14h 05m
United Airlines
Deal found 3/18$951
This United Airlines deal was found by Cheapflights users on 3/19. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 5/210:25 am
LIS
-
STL
1 stop12h 18m
United Airlines
Tue 5/510:25 am
STL
-
LIS
2 stops15h 55m
United Airlines
Deal found 3/19$955

Find flight deals from Portugal to Missouri

Keep the following information in mind while searching for Portugal to Missouri flight deals. Data was last updated March 22, 2026.

Most accurate provider

FlightHub
3 stars

Most trusted provider

FlightHub
3 stars

Round-trip from

$895
(United Airlines)

One-way from

$379
(Kiwi.com)
Provider with most accurate pricing for Lisbon Humberto Delgado-Lambert-St Louis flight deals.
Search Deals
Provider most trusted by Cheapflights users for Lisbon Humberto Delgado-Lambert-St Louis flights.
Search Deals
From Portugal to Missouri
Search Deals
One-way flight from Portugal to Missouri
Search Deals

Cheapflights Fare Finder

 
Customize your flight search to find flights from Portugal to Missouri that fit within your specific budget. Explore options based on user searches and filter the results based on your desired price range. Find flights that match your budget for a cost-effective journey. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated March 22, 2026.
Use the filters below to find and compare flights from Portugal to Missouri that are best for you.

Fly from

Fly to

Route

Depart

Return

Price

Cheapest round-trip

PortoSt. Louis

OPO - STL

OPOSTL

Porto

Wed 4/1

12:00 pm-11:11 pm

2 stops17h 11m

Lambert-St Louis

Sun 4/5

9:10 am-9:45 am

2 stops18h 35m

$895

LisbonSt. Louis

LIS - STL

LISSTL

Lisbon Humberto Delgado

Thu 4/30

7:25 am-1:25 pm

1 stop36h 00m

Lambert-St Louis

Mon 5/4

8:45 am-10:30 am

1 stop19h 45m

$921

LisbonSt. Louis

LIS - STL

LISSTL

Lisbon Humberto Delgado

Fri 4/17

5:05 am-1:25 pm

1 stop14h 20m

Lambert-St Louis

Tue 4/21

6:15 am-8:20 am

1 stop20h 05m

$923

LisbonSt. Louis

LIS - STL

LISSTL

Lisbon Humberto Delgado

Wed 6/10

10:00 am-4:55 pm

1 stop12h 55m

Lambert-St Louis

Wed 6/24

2:18 pm-2:55 pm

2 stops18h 37m

$930

LisbonSt. Louis

LIS - STL

LISSTL

Lisbon Humberto Delgado

Fri 4/17

5:05 am-1:25 pm

1 stop14h 20m

Lambert-St Louis

Tue 4/21

1:10 pm-3:35 pm

2 stops20h 25m

$932

LisbonSt. Louis

LIS - STL

LISSTL

Lisbon Humberto Delgado

Tue 6/9

5:05 am-1:25 pm

1 stop14h 20m

Lambert-St Louis

Wed 6/24

1:15 pm-9:20 am

1 stop14h 05m

$941

LisbonSt. Louis

LIS - STL

LISSTL

Lisbon Humberto Delgado

Wed 6/10

5:05 am-1:25 pm

1 stop14h 20m

Lambert-St Louis

Wed 6/24

1:15 pm-9:20 am

1 stop14h 05m

$941

LisbonSt. Louis

LIS - STL

LISSTL

Lisbon Humberto Delgado

Fri 6/12

5:05 am-6:13 pm

2 stops19h 08m

Lambert-St Louis

Wed 6/24

1:15 pm-9:20 am

1 stop14h 05m

$951
Quickest round-trip

LisbonSt. Louis

LIS - STL

LISSTL

Lisbon Humberto Delgado

Sat 5/2

10:25 am-4:43 pm

1 stop12h 18m

Lambert-St Louis

Tue 5/5

10:25 am-8:20 am

2 stops15h 55m

$955

LisbonJoplin

LIS - JLN

LISJLN

Lisbon Humberto Delgado

Wed 4/22

6:45 am-1:12 pm

2 stops36h 27m

Joplin

Sun 4/26

8:56 am-10:30 am

2 stops19h 34m

$964

Flights are sorted by cheapest round-trip flights first.

Deals found on 3/19

Showing 1-10 of 54 resultsSorted by cheapest first
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Best time to book a flight from Portugal to Missouri

Have a flexible travel schedule? Discover the best time to fly to Missouri from Portugal with our price prediction graph.
Estimated round-trip price
Rates are based on past data. Find the cheapest month and day to book your flight based on your travel requirements, then search for cheap deals.

Cheapflights Insights

Everything you need to know about your flight from Portugal to Missouri
No data available for this route at this time. Please check back soon.

Related info for your journey

Find useful and relevant information for your journey from Portugal to Missouri. Access travel guides, tips, and recommendations to enhance your travel experience. Get information about local attractions, weather, transportation options, and more.

  • How long is the flight from Portugal to Missouri?

    United Airlines, Delta, and Lufthansa can get you from Portugal to Missouri in just under 12h 55m. Your travel time can differ by up to 4h 16m. Portugal and Missouri are separated by a distance of 4212 mi. When browsing for deals, the options you’ll see will be for both nonstop flights and flights with stops.

  • Can I find deals for flights from Portugal to Missouri that include hotel bookings?

    Yes. In addition to deals on Portugal to Missouri flights, Cheapflights offers vacation packages that include both flights and hotel.

  • How can I find direct flights from Portugal to Missouri?

    After entering your origin and destination, apply the non-stop filter on the search result page to find direct flights from Portugal to Missouri.

  • Can I find deals for business class flights from Portugal to Missouri?

    Yes. Cheapflights offers flight deals from Portugal to Missouri by cabin class. In addition to browsing deals, you can also filter by cabin class on the search results page after making a search.

See more FAQs

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Alternative routes for Portugal to Missouri

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