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$100+ Cheap flights from Panama City, FL (ECP) to Missouri

This is the cheapest one-way flight price found by a Cheapflights user in the last 72 hours by searching for a flight departing on 7/19. Fares are subject to change and may not be available on all flights or dates of travel.
ECP — STL
may. 4 — may. 111
dom. 5/4
dom. 5/11
1 adult, Economy
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Cheap flight deals from Panama City to Missouri

Keep the following information in mind while searching for Panama City to Missouri flight deals. Data was last updated abril 29, 2025.

Most accurate provider

FlightHub
3 stars

Most trusted provider

eDreams
3 stars

Round-trip from

$274
(Delta)

One-way from

$100
(American Airlines)

Popular in

October

Cheapest in

June

Average price

$332

Good round-trip deal

$263 or less

Good one-way deal

$193 or less
Provider with most accurate pricing for Panama City NW Florida Beaches-Kansas City flight deals.
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Provider most trusted by Cheapflights users for Panama City NW Florida Beaches-Kansas City flights.
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From Panama City NW Florida Beaches to Missouri
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One-way flight from Panama City NW Florida Beaches to Missouri
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Highest demand for flights based on searches. 9% potential increase in price ($43 potential increase over avg. RT price).
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Cheapest flight prices on average. 6% potential price decrease ($24 potential savings vs. average RT price).
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Average for round-trip flights in April 2025
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Price to beat on a round-trip flight from Panama City NW Florida Beaches to Missouri.
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Price to beat on a one-way flight from Panama City NW Florida Beaches to Missouri.
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Find flight deals from Panama City to Missouri

Cheapest flights from Panama City to Missouri
Explore the most affordable flight options available from Panama City to Missouri. Find the lowest fares from popular airlines and budget airlines, with prices last updated on abril 29, 2025.

This Delta deal was found by Cheapflights users on 4/27. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
mié. 5/219:12 amECP - MCI
1 stop5h 31mDelta
mié. 5/287:00 amMCI - ECP
1 stop6h 04mDelta
Deal found 4/27$297
This American Airlines deal was found by Cheapflights users on 4/28. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
mié. 5/2112:25 pmECP - MCI
2 stops9h 06mAmerican Airlines
mié. 5/285:15 amMCI - ECP
1 stop5h 48mAmerican Airlines
Deal found 4/28$302
This Delta deal was found by Cheapflights users on 4/28. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
jue. 5/299:12 amECP - SGF
1 stop5h 53mDelta
vie. 6/66:56 pmSGF - ECP
1 stop4h 08mDelta
Deal found 4/28$314
This American Airlines deal was found by Cheapflights users on 4/28. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
mar. 6/32:29 pmECP - SGF
1 stop7h 28mAmerican Airlines
sáb. 6/75:00 amSGF - ECP
1 stop4h 01mAmerican Airlines
Deal found 4/28$336
This United Airlines deal was found by Cheapflights users on 4/28. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
jue. 5/296:30 amECP - SGF
1 stop7h 28mUnited Airlines
mar. 6/33:00 pmSGF - ECP
1 stop7h 00mUnited Airlines
Deal found 4/28$344
This Delta deal was found by Cheapflights users on 4/28. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
mar. 5/137:15 amECP - STL
1 stop4h 49mDelta
sáb. 5/175:00 pmSTL - ECP
1 stop4h 19mDelta
Deal found 4/28$377
This United Airlines deal was found by Cheapflights users on 4/28. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
mar. 5/138:50 amECP - STL
1 stop6h 59mUnited Airlines
sáb. 5/179:40 amSTL - ECP
2 stops8h 46mUnited Airlines
Deal found 4/28$382
This American Airlines deal was found by Cheapflights users on 4/28. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
mar. 5/132:29 pmECP - STL
2 stops9h 22mAmerican Airlines
sáb. 5/175:12 amSTL - ECP
2 stops8h 37mAmerican Airlines
Deal found 4/28$387
This Southwest deal was found by Cheapflights users on 4/29. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
mar. 7/229:30 amECP - MCI
2 stops8h 40mSouthwest
lun. 8/46:50 amMCI - ECP
2 stops10h 35mSouthwest
Deal found 4/29$397
This Southwest deal was found by Cheapflights users on 4/28. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
sáb. 7/263:40 pmECP - STL
2 stops7h 25mSouthwest
sáb. 8/210:15 amSTL - ECP
2 stops8h 45mSouthwest
Deal found 4/28$497
This United Airlines deal was found by Cheapflights users on 4/27. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
lun. 4/284:58 pmECP - MCI
1 stop5h 21mUnited Airlines
mié. 4/306:20 amMCI - ECP
1 stop6h 20mUnited Airlines
Deal found 4/27$769

Cheapflights Fare Finder

Customize your flight search to find flights from Panama City to Missouri that fit within your specific budget. Explore options based on user searches and filter the results based on your desired price range. Find flights that match your budget for a cost-effective journey. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated abril 29, 2025.
Use the filters below to find and compare flights from Panama City to Missouri that are best for you.

Fly from

Panama City

Fly to

Missouri

Route

Depart

Return

Price

Panama CityKansas City

ECP - MCI

ECPMCI

Panama City NW Florida Beaches

mié. 5/21

9:12 am-2:43 pm

1 stop5h 31m

Kansas City

mié. 5/28

7:00 am-1:04 pm

1 stop6h 04m

$297

Panama CityKansas City

ECP - MCI

ECPMCI

Panama City NW Florida Beaches

mié. 5/21

12:25 pm-9:31 pm

2 stops9h 06m

Kansas City

mié. 5/28

5:15 am-11:03 am

1 stop5h 48m

$302

Panama CitySpringfield

ECP - SGF

ECPSGF

Panama City NW Florida Beaches

jue. 5/29

9:12 am-3:05 pm

1 stop5h 53m

Springfield-Branson

vie. 6/6

6:56 pm-11:04 pm

1 stop4h 08m

$314

Panama CitySpringfield

ECP - SGF

ECPSGF

Panama City NW Florida Beaches

mar. 6/3

2:29 pm-9:57 pm

1 stop7h 28m

Springfield-Branson

sáb. 6/7

5:00 am-9:01 am

1 stop4h 01m

$336

Panama CitySpringfield

ECP - SGF

ECPSGF

Panama City NW Florida Beaches

jue. 5/29

6:30 am-1:58 pm

1 stop7h 28m

Springfield-Branson

mar. 6/3

3:00 pm-10:00 pm

1 stop7h 00m

$344

Panama CitySt. Louis

ECP - STL

ECPSTL

Panama City NW Florida Beaches

mar. 5/13

7:15 am-12:04 pm

1 stop4h 49m

Lambert-St Louis

sáb. 5/17

5:00 pm-9:19 pm

1 stop4h 19m

$377

Panama CitySt. Louis

ECP - STL

ECPSTL

Panama City NW Florida Beaches

mar. 5/13

8:50 am-3:49 pm

1 stop6h 59m

Lambert-St Louis

sáb. 5/17

9:40 am-6:26 pm

2 stops8h 46m

$382

Panama CitySt. Louis

ECP - STL

ECPSTL

Panama City NW Florida Beaches

mar. 5/13

2:29 pm-11:51 pm

2 stops9h 22m

Lambert-St Louis

sáb. 5/17

5:12 am-1:49 pm

2 stops8h 37m

$387

Panama CityKansas City

ECP - MCI

ECPMCI

Panama City NW Florida Beaches

mar. 7/22

9:30 am-6:10 pm

2 stops8h 40m

Kansas City

lun. 8/4

6:50 am-5:25 pm

2 stops10h 35m

$397

Panama CitySt. Louis

ECP - STL

ECPSTL

Panama City NW Florida Beaches

sáb. 7/26

7:40 pm-11:05 pm

1 stop3h 25m

Lambert-St Louis

sáb. 8/2

10:15 am-7:00 pm

2 stops8h 45m

$422

Flights are sorted by cheapest round-trip flights first.

Deals found on 4/29

Showing 1-10 of 20 results
1
2

Best time to book a flight from Panama City to Missouri

Have a flexible travel schedule? Discover the best time to fly to Missouri from Panama City with our price prediction graph.
Estimated round-trip price
Rates are based on past data. Find the cheapest month and day to book your flight based on your travel requirements, then search for cheap deals.

Cheapflights Insights

Everything you need to know about your flight from Panama City to Missouri

What is the cheapest month to book a flight from Panama City, Florida to Missouri?

Currently, August is the cheapest month in which you can book a flight from Panama City, Florida to Missouri (average of $311). Flying from Panama City, Florida to Missouri in March is currently the most expensive (average of $356). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.

What is the cheapest time of day to fly from ECP to MO?

Find hourly flight availability from Panama City to Missouri. Discover flight options and departure times throughout the day, allowing you to choose a departure time that suits your schedule. Data last updated abril 29, 2025.

Regardless of the time of day you decide to fly, the ticket price will remain around the same. Book flights from Panama City, Florida to Missouri as you normally would.

Rainfall in Missouri by month

Plan your trip to Missouri by taking into account the average rainfall totals by month.

In terms of precipitation, rainfall in Missouri ranges from 1.1 - 5.2 inches per month. May is typically the wettest month, when rainfall can reach 5.2 in. January is typically the driest time to visit Missouri when rainfall is around 1.1 in.

Temperature in Missouri by month

Plan your trip to Missouri by taking into account the average temperature totals by month.

If weather is an important factor for your trip to Missouri, use this chart to help with planning. For those seeking warmer temperatures, July is the ideal time of year to visit, when temperatures reach an average of 78.8 F. Travelers looking to avoid the cold should look outside of January, when temperatures are typically at their lowest (around 28.4 F).

Reviews of airlines servicing Missouri

Get insights into the airlines that provide service to Missouri. Read reviews, discover amenities, and learn about the overall travel experience offered by airlines. Use this information to make informed decisions when choosing an airline for your flight to Missouri. Reviews last updated abril 29, 2025.
Read through reviews of airlines operating flights from Panama City to Missouri, such as Southwest, Delta and United Airlines. You can also see how each airline compares in terms of entertainment options, comfort, food, crew/service, and boarding process.
Southwest
8.0
Very good
4,295 reviews

Crew

8.6

Entertainment

7.6

Boarding

8.2

Comfort

8.0

Food

7.1

Overall

8.0

Reviews

1 / 20
10.0
Excellent

Gina,Apr 2025

LAS - DEN

Good, the crew was friendly and helpful. The pilot had great skills in keeping the plane stable through rough turbulence. Smooth landing, too! Thank you!
Southwest
8.0
Very good
4,295 reviews
Southwest
8.0
Very good
4,295 reviews

Crew

8.6

Entertainment

7.6

Boarding

8.2

Comfort

8.0

Food

7.1

Overall

8.0

Reviews

1 / 20
10.0
Excellent

Gina,Apr 2025

LAS - DEN

Good, the crew was friendly and helpful. The pilot had great skills in keeping the plane stable through rough turbulence. Smooth landing, too! Thank you!
Delta
8.0
Very good
7,936 reviews
Southwest
8.0
Very good
4,295 reviews

Crew

8.6

Entertainment

7.6

Boarding

8.2

Comfort

8.0

Food

7.1

Overall

8.0

Reviews

1 / 20
10.0
Excellent

Gina,Apr 2025

LAS - DEN

Good, the crew was friendly and helpful. The pilot had great skills in keeping the plane stable through rough turbulence. Smooth landing, too! Thank you!
United Airlines
7.4
Good
8,696 reviews
Southwest
8.0
Very good
4,295 reviews

Crew

8.6

Entertainment

7.6

Boarding

8.2

Comfort

8.0

Food

7.1

Overall

8.0

Reviews

1 / 20
10.0
Excellent

Gina,Apr 2025

LAS - DEN

Good, the crew was friendly and helpful. The pilot had great skills in keeping the plane stable through rough turbulence. Smooth landing, too! Thank you!
American Airlines
7.2
Good
10,000 reviews
Southwest
8.0
Very good
4,295 reviews

Crew

8.6

Entertainment

7.6

Boarding

8.2

Comfort

8.0

Food

7.1

Overall

8.0

Reviews

1 / 20
10.0
Excellent

Gina,Apr 2025

LAS - DEN

Good, the crew was friendly and helpful. The pilot had great skills in keeping the plane stable through rough turbulence. Smooth landing, too! Thank you!

Related info for your journey

Find useful and relevant information for your journey from Panama City to Missouri. Access travel guides, tips, and recommendations to enhance your travel experience. Get information about local attractions, weather, transportation options, and more.

  • What airport do you fly from for flights from Panama City to Missouri?

    If you book a flight to Missouri from Panama City, you will be flying from NW Florida Beaches, which is the city’s only airport. Panama City NW Florida Beaches (ECP) is located 16.0 mi from the center of Panama City.

  • What are the cheapest airlines to fly from Panama City, Florida to Missouri one-way?

    One-way options have recently been found by users for as low as $100 on American Airlines. Other airlines that offer cheap prices include Southwest from $139 and Delta from $144 one-way.

  • What are the most popular routes from Panama City, Florida to Missouri?

    Most travelers choose Panama City NW Florida Beaches - Kansas City, Panama City NW Florida Beaches - Lambert-St Louis or Panama City NW Florida Beaches - Springfield-Branson when deciding on the best route from Panama City, Florida to Missouri.

  • What are the cheapest flights from Panama City, Florida to Missouri?

    The cheapest flight price from Panama City, Florida to Missouri is $138. On average you can expect to pay $338. The most popular route, (Panama City NW Florida Beaches - Kansas City), can usually be booked for $297.

  • Can I find deals for flights from Panama City to Missouri that include hotel bookings?

    Yes. In addition to deals on Panama City to Missouri flights, Cheapflights offers vacation packages that include both flights and hotel.

  • How can I find direct flights from Panama City to Missouri?

    After entering your origin and destination, apply the non-stop filter on the search result page to find direct flights from Panama City to Missouri.

  • Can I find deals for business class flights from Panama City to Missouri?

    Yes. Cheapflights offers flight deals from Panama City to Missouri by cabin class. In addition to browsing deals, you can also filter by cabin class on the search results page after making a search.

  • What is the cheapest month to book a flight from Panama City, Florida to Missouri?

    Currently, August is the cheapest month in which you can book a flight from Panama City, Florida to Missouri (average of $311). Flying from Panama City, Florida to Missouri in March is currently the most expensive (average of $356). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.

See more FAQs

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See prices for flight routes from nearby airports that may be better suited for you.
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Top 4 airlines flying from Panama City to Missouri

Discover the top 4 airlines that operate flights from Panama City to Missouri. Compare their services, reliability, and customer satisfaction ratings to choose the airline that best suits your travel preferences and needs. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated abril 29, 2025.
AirlineCheapestAverageFlexibilityOn-time
American AirlinesCheapest$182Average$359FlexibilityNo cancel feeOn-time71%
DeltaCheapest$216Average$388FlexibilityNo cancel feeOn-timeN/A
SouthwestCheapest$242Average$430FlexibilityNo cancel feeOn-time63%
United AirlinesCheapest$258Average$353FlexibilityNo cancel feeOn-time69%

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