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$79+ Cheap flights from Panama City, FL (ECP) to Missouri

This is the cheapest one-way flight price found by a Cheapflights user in the last 72 hours by searching for a flight departing on 9/11. Fares are subject to change and may not be available on all flights or dates of travel.
ECP — STL
ago. 4 — ago. 111
lun. 8/4
lun. 8/11
1 adult, Economy
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Cheap flight deals from Panama City to Missouri

Keep the following information in mind while searching for Panama City to Missouri flight deals. Data was last updated julio 30, 2025.

Round-trip from

$157
(Southwest)

One-way from

$79
(Southwest)

Popular in

February

Cheapest in

August

Average price

$378

Good round-trip deal

$194 or less

Good one-way deal

$129 or less
From Panama City NW Florida Beaches to Missouri
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One-way flight from Panama City NW Florida Beaches to Missouri
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Highest demand for flights based on searches. 17% potential increase in price ($84 potential increase over avg. RT price).
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Cheapest flight prices on average. 3% potential price decrease ($14 potential savings vs. average RT price).
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Average for round-trip flights in July 2025
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Price to beat on a round-trip flight from Panama City NW Florida Beaches to Missouri.
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Price to beat on a one-way flight from Panama City NW Florida Beaches to Missouri.
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Find flight deals from Panama City to Missouri

Cheapest flights from Panama City to Missouri
Explore the most affordable flight options available from Panama City to Missouri. Find the lowest fares from popular airlines and budget airlines, with prices last updated on julio 30, 2025.

This Southwest deal was found by Cheapflights users on 7/28. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
jue. 8/281:35 pmECP - STL
Nonstop1h 50mSouthwest
lun. 9/13:10 pmSTL - ECP
Nonstop1h 45mSouthwest
Deal found 7/28$157
This Delta deal was found by Cheapflights users on 7/27. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
jue. 10/211:00 amECP - STL
1 stop5h 05mDelta
lun. 10/135:15 pmSTL - ECP
1 stop5h 55mDelta
Deal found 7/27$177
This American Airlines deal was found by Cheapflights users on 7/28. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
jue. 8/285:30 amECP - STL
1 stop6h 41mAmerican Airlines
lun. 9/16:00 amSTL - ECP
1 stop6h 48mAmerican Airlines
Deal found 7/28$187
This American Airlines deal was found by Cheapflights users on 7/29. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
sáb. 8/305:30 amECP - MCI
1 stop4h 47mAmerican Airlines
sáb. 9/610:46 amMCI - ECP
1 stop4h 32mAmerican Airlines
Deal found 7/29$227
This Delta deal was found by Cheapflights users on 7/29. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
sáb. 8/306:00 amECP - MCI
1 stop7h 09mDelta
lun. 9/15:45 amMCI - ECP
1 stop4h 49mDelta
Deal found 7/29$242
This American Airlines deal was found by Cheapflights users on 7/29. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
jue. 8/212:33 pmECP - SGF
1 stop7h 10mAmerican Airlines
lun. 8/258:23 amSGF - ECP
1 stop6h 28mAmerican Airlines
Deal found 7/29$249
This Delta deal was found by Cheapflights users on 7/28. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
sáb. 9/66:00 amECP - SGF
1 stop4h 56mDelta
mié. 9/105:59 pmSGF - ECP
1 stop5h 07mDelta
Deal found 7/28$279
This Southwest deal was found by Cheapflights users on 7/29. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
sáb. 9/134:10 pmECP - MCI
1 stop4h 40mSouthwest
sáb. 9/206:45 amMCI - ECP
2 stops8h 50mSouthwest
Deal found 7/29$290
This United Airlines deal was found by Cheapflights users on 7/29. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
mié. 8/2711:09 amECP - STL
1 stop7h 49mUnited Airlines
mié. 9/36:35 amSTL - ECP
2 stops9h 45mUnited Airlines
Deal found 7/29$302
This United Airlines deal was found by Cheapflights users on 7/28. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
sáb. 9/62:26 pmECP - SGF
2 stops9h 13mUnited Airlines
mié. 9/102:50 pmSGF - ECP
1 stop5h 26mUnited Airlines
Deal found 7/28$384

Cheapflights Fare Finder

 
Customize your flight search to find flights from Panama City to Missouri that fit within your specific budget. Explore options based on user searches and filter the results based on your desired price range. Find flights that match your budget for a cost-effective journey. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated julio 30, 2025.
Use the filters below to find and compare flights from Panama City to Missouri that are best for you.

Fly from

Panama City

Fly to

Missouri

Route

Depart

Return

Price

Panama CitySt. Louis

ECP - STL

ECPSTL

Panama City NW Florida Beaches

sáb. 8/30

3:15 pm-5:05 pm

Nonstop1h 50m

Lambert-St Louis

sáb. 9/6

3:30 pm-5:15 pm

Nonstop1h 45m

$157

Panama CitySt. Louis

ECP - STL

ECPSTL

Panama City NW Florida Beaches

mié. 8/27

9:24 am-2:37 pm

1 stop5h 13m

Lambert-St Louis

mié. 9/3

1:26 pm-7:48 pm

1 stop6h 22m

$177

Panama CitySt. Louis

ECP - STL

ECPSTL

Panama City NW Florida Beaches

vie. 8/29

3:22 pm-10:59 pm

1 stop7h 37m

Lambert-St Louis

lun. 9/1

6:02 am-12:07 pm

1 stop6h 05m

$187

Panama CityKansas City

ECP - MCI

ECPMCI

Panama City NW Florida Beaches

sáb. 8/30

5:30 am-10:17 am

1 stop4h 47m

Kansas City

sáb. 9/6

10:46 am-3:18 pm

1 stop4h 32m

$227

Panama CityKansas City

ECP - MCI

ECPMCI

Panama City NW Florida Beaches

sáb. 8/30

6:00 am-1:09 pm

1 stop7h 09m

Kansas City

lun. 9/1

5:45 am-10:34 am

1 stop4h 49m

$242

Panama CitySpringfield

ECP - SGF

ECPSGF

Panama City NW Florida Beaches

jue. 8/21

2:33 pm-9:43 pm

1 stop7h 10m

Springfield-Branson

lun. 8/25

8:23 am-2:51 pm

1 stop6h 28m

$249

Panama CitySpringfield

ECP - SGF

ECPSGF

Panama City NW Florida Beaches

sáb. 9/6

6:00 am-10:56 am

1 stop4h 56m

Springfield-Branson

mié. 9/10

5:59 pm-11:06 pm

1 stop5h 07m

$279

Panama CityKansas City

ECP - MCI

ECPMCI

Panama City NW Florida Beaches

sáb. 9/13

4:10 pm-8:50 pm

1 stop4h 40m

Kansas City

sáb. 9/20

6:45 am-3:35 pm

2 stops8h 50m

$290

Panama CitySt. Louis

ECP - STL

ECPSTL

Panama City NW Florida Beaches

mié. 8/27

6:30 am-2:26 pm

1 stop7h 56m

Lambert-St Louis

sáb. 9/6

6:35 am-4:20 pm

2 stops9h 45m

$302

Panama CitySpringfield

ECP - SGF

ECPSGF

Panama City NW Florida Beaches

sáb. 9/6

2:26 pm-11:39 pm

2 stops9h 13m

Springfield-Branson

mié. 9/10

2:50 pm-8:16 pm

1 stop5h 26m

$384

Flights are sorted by cheapest round-trip flights first.

Deals found on 7/29

Showing 1-10 of 22 results
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Best time to book a flight from Panama City to Missouri

Have a flexible travel schedule? Discover the best time to fly to Missouri from Panama City with our price prediction graph.
Estimated round-trip price
Rates are based on past data. Find the cheapest month and day to book your flight based on your travel requirements, then search for cheap deals.

Cheapflights Insights

Everything you need to know about your flight from Panama City to Missouri

What is the cheapest month to book a flight from Panama City, Florida to Missouri?

Currently, August is the cheapest month in which you can book a flight from Panama City, Florida to Missouri (average of $311). Flying from Panama City, Florida to Missouri in March is currently the most expensive (average of $356). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.

What is the cheapest time of day to fly from ECP to MO?

Find hourly flight availability from Panama City to Missouri. Discover flight options and departure times throughout the day, allowing you to choose a departure time that suits your schedule. Data last updated julio 30, 2025.

Regardless of the time of day you decide to fly, the ticket price will remain around the same. Book flights from Panama City, Florida to Missouri as you normally would.

Reviews of airlines servicing Missouri

Get insights into the airlines that provide service to Missouri. Read reviews, discover amenities, and learn about the overall travel experience offered by airlines. Use this information to make informed decisions when choosing an airline for your flight to Missouri. Reviews last updated julio 30, 2025.
Get a feel of what it's like to fly with Southwest, Delta, and United Airlines from Panama City to Missouri by reading reviews from past customers. You can also see how each airline compares in terms of entertainment options, comfort, food, crew/service, and boarding process.
Southwest
8.0
Very good
4,241 reviews

Overall

8.0

Crew

8.6

Food

7.0

Boarding

8.1

Comfort

8.0

Entertainment

7.5

Reviews

1 / 20
8.0
Excellent

Gina,Jul 2025

LAS - DEN

We experienced bad weather, which turned our 1.5 hour flight from Las Vegas to Denver, into 3.5. The pilot and crew kept us updated and explained that we had to circle and or possibly redirect to another airport. After circling for sometime, we were able to land smoothly in Denver. Thank you to all the flight crew, tower control, and all who got us to our destination safely.
Southwest
8.0
Very good
4,241 reviews
Southwest
8.0
Very good
4,241 reviews

Overall

8.0

Crew

8.6

Food

7.0

Boarding

8.1

Comfort

8.0

Entertainment

7.5

Reviews

1 / 20
8.0
Excellent

Gina,Jul 2025

LAS - DEN

We experienced bad weather, which turned our 1.5 hour flight from Las Vegas to Denver, into 3.5. The pilot and crew kept us updated and explained that we had to circle and or possibly redirect to another airport. After circling for sometime, we were able to land smoothly in Denver. Thank you to all the flight crew, tower control, and all who got us to our destination safely.
Delta
8.0
Very good
7,980 reviews
Southwest
8.0
Very good
4,241 reviews

Overall

8.0

Crew

8.6

Food

7.0

Boarding

8.1

Comfort

8.0

Entertainment

7.5

Reviews

1 / 20
8.0
Excellent

Gina,Jul 2025

LAS - DEN

We experienced bad weather, which turned our 1.5 hour flight from Las Vegas to Denver, into 3.5. The pilot and crew kept us updated and explained that we had to circle and or possibly redirect to another airport. After circling for sometime, we were able to land smoothly in Denver. Thank you to all the flight crew, tower control, and all who got us to our destination safely.
United Airlines
7.4
Good
8,896 reviews
Southwest
8.0
Very good
4,241 reviews

Overall

8.0

Crew

8.6

Food

7.0

Boarding

8.1

Comfort

8.0

Entertainment

7.5

Reviews

1 / 20
8.0
Excellent

Gina,Jul 2025

LAS - DEN

We experienced bad weather, which turned our 1.5 hour flight from Las Vegas to Denver, into 3.5. The pilot and crew kept us updated and explained that we had to circle and or possibly redirect to another airport. After circling for sometime, we were able to land smoothly in Denver. Thank you to all the flight crew, tower control, and all who got us to our destination safely.
American Airlines
7.2
Good
10,000 reviews
Southwest
8.0
Very good
4,241 reviews

Overall

8.0

Crew

8.6

Food

7.0

Boarding

8.1

Comfort

8.0

Entertainment

7.5

Reviews

1 / 20
8.0
Excellent

Gina,Jul 2025

LAS - DEN

We experienced bad weather, which turned our 1.5 hour flight from Las Vegas to Denver, into 3.5. The pilot and crew kept us updated and explained that we had to circle and or possibly redirect to another airport. After circling for sometime, we were able to land smoothly in Denver. Thank you to all the flight crew, tower control, and all who got us to our destination safely.

Related info for your journey

Find useful and relevant information for your journey from Panama City to Missouri. Access travel guides, tips, and recommendations to enhance your travel experience. Get information about local attractions, weather, transportation options, and more.

  • What airport do you fly from for flights from Panama City to Missouri?

    If you book a flight to Missouri from Panama City, you will be flying from NW Florida Beaches, which is the city’s only airport. Panama City NW Florida Beaches (ECP) is located 16.0 mi from the center of Panama City.

  • What are the cheapest airlines to fly from Panama City, Florida to Missouri one-way?

    One-way options have recently been found by users for as low as $79 on Southwest. Other airlines that offer cheap prices include Delta from $89 and American Airlines from $93 one-way.

  • What are the most popular routes from Panama City, Florida to Missouri?

    Most travelers choose Panama City NW Florida Beaches - Kansas City, Panama City NW Florida Beaches - Lambert-St Louis or Panama City NW Florida Beaches - Springfield-Branson when deciding on the best route from Panama City, Florida to Missouri.

  • What are the cheapest flights from Panama City, Florida to Missouri?

    The cheapest flight price from Panama City, Florida to Missouri is $66. On average you can expect to pay $233. The most popular route, (Panama City NW Florida Beaches - Kansas City), can usually be booked for $227.

  • Can I find deals for flights from Panama City to Missouri that include hotel bookings?

    Yes. In addition to deals on Panama City to Missouri flights, Cheapflights offers vacation packages that include both flights and hotel.

  • How can I find direct flights from Panama City to Missouri?

    After entering your origin and destination, apply the non-stop filter on the search result page to find direct flights from Panama City to Missouri.

  • Can I find deals for business class flights from Panama City to Missouri?

    Yes. Cheapflights offers flight deals from Panama City to Missouri by cabin class. In addition to browsing deals, you can also filter by cabin class on the search results page after making a search.

  • What is the cheapest month to book a flight from Panama City, Florida to Missouri?

    Currently, August is the cheapest month in which you can book a flight from Panama City, Florida to Missouri (average of $311). Flying from Panama City, Florida to Missouri in March is currently the most expensive (average of $356). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.

See more FAQs

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Alternative routes for Panama City to Missouri

See prices for flight routes from nearby airports that may be better suited for you.
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Top 4 airlines flying from Panama City to Missouri

Discover the top 4 airlines that operate flights from Panama City to Missouri. Compare their services, reliability, and customer satisfaction ratings to choose the airline that best suits your travel preferences and needs. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated julio 30, 2025.
AirlineCheapestAverageFlexibilityOn-time
American AirlinesCheapest$158Average$395FlexibilityNo cancel feeOn-time71%
DeltaCheapest$176Average$368FlexibilityNo cancel feeOn-timeN/A
SouthwestCheapest$194Average$403FlexibilityNo cancel feeOn-time63%
United AirlinesCheapest$401Average$401FlexibilityNo cancel feeOn-time69%

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