$76+ Cheap flights from Mississippi to Missouri
This is the cheapest one-way flight price found by a Cheapflights user in the last 72 hours by searching for a flight departing on 4/12. Fares are subject to change and may not be available on all flights or dates of travel.
JAN — STL
Apr 22 — Apr 291
Round-trip
1 adult, Economy
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Find cheap flights from Mississippi to Missouri with Cheapflights
1. Tell us where you want to go
Enter your travel information like dates, passengers, trip type (one-way or round trip), and preferred cabin class then click “Find deals”2. Select your favorite providers
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Cheapest flights from Mississippi to MissouriExplore the most affordable flight options available from Mississippi to Missouri. Find the lowest fares from popular airlines and budget airlines, with prices last updated on March 23, 2026.
Explore the most affordable flight options available from Mississippi to Missouri. Find the lowest fares from popular airlines and budget airlines, with prices last updated on March 23, 2026.
This Orbitz deal was found by Cheapflights users on 3/19. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Orbitz is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 4/124:31 pm
MEM
- STL
1 stop17h 17m
Frontier
Sun 4/1911:16 am
STL
- MEM
1 stop6h 26m
Frontier
Deal found 3/19![Frontier logo]()
$180
This Frontier deal was found by Cheapflights users on 3/18. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Frontier is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 4/28:30 pm
MEM
- STL
1 stop14h 57m
Frontier
Sun 4/511:21 am
STL
- MEM
1 stop5h 48m
Frontier
Deal found 3/18![Frontier logo]()
$250
This CheapOair deal was found by Cheapflights users on 3/19. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure CheapOair is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 3/268:30 pm
MEM
- STL
1 stop14h 49m
Frontier
Sat 4/118:16 pm
STL
- MEM
1 stop19h 20m
Frontier
Deal found 3/19![Frontier logo]()
$251
This Delta deal was found by Cheapflights users on 3/22. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 4/215:55 pm
GPT
- MCI
1 stop5h 55m
Delta
Tue 4/285:12 pm
MCI
- GPT
1 stop5h 01m
Delta
Deal found 3/22![Delta logo]()
$277
This Kiwi.com deal was found by Cheapflights users on 3/20. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 5/711:59 am
MEM
- MCI
2 stops25h 50m
Multiple Airlines
Sun 5/108:44 am
MCI
- MEM
1 stop9h 31m
Multiple Airlines
Deal found 3/20![Multiple Airlines logo]()
$283
This Delta deal was found by Cheapflights users on 3/19. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 4/75:57 pm
GPT
- STL
1 stop6h 01m
Delta
Thu 4/97:03 am
STL
- GPT
1 stop6h 57m
Delta
Deal found 3/19![Delta logo]()
$285
This United Airlines deal was found by Cheapflights users on 3/19. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 4/44:26 pm
GPT
- STL
1 stop6h 02m
United Airlines
Wed 4/89:10 am
STL
- GPT
2 stops10h 43m
United Airlines
Deal found 3/19![United Airlines logo]()
$290
This Kiwi.com deal was found by Cheapflights users on 3/19. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 4/196:42 pm
MEM
- STL
1 stop12h 08m
Multiple Airlines
Wed 4/228:23 pm
STL
- MEM
2 stops34h 52m
Multiple Airlines
Deal found 3/19![Multiple Airlines logo]()
$293
This Southwest deal was found by Cheapflights users on 3/20. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 4/143:25 pm
MEM
- MCI
1 stop3h 25m
Southwest
Mon 4/205:15 pm
MCI
- MEM
1 stop5h 45m
Southwest
Deal found 3/20![Southwest logo]()
$300
This Kiwi.com deal was found by Cheapflights users on 3/19. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 4/196:42 pm
MEM
- STL
1 stop12h 08m
Frontier
Wed 4/228:23 pm
STL
- MEM
1 stop20h 53m
Frontier
Deal found 3/19![Frontier logo]()
$302
This United Airlines deal was found by Cheapflights users on 3/19. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 11/1811:55 am
GPT
- MCI
2 stops8h 57m
United Airlines
Thu 11/266:10 am
MCI
- GPT
1 stop5h 11m
United Airlines
Deal found 3/19![United Airlines logo]()
$302
This American Airlines deal was found by Cheapflights users on 3/21. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 5/77:37 pm
GPT
- MCI
1 stop4h 30m
American Airlines
Mon 5/115:30 am
MCI
- GPT
1 stop5h 03m
American Airlines
Deal found 3/21![American Airlines logo]()
$303
Best flights from Mississippi to MissouriDiscover carefully curated flight deals from Mississippi to Missouri that have cost, travel time, and layovers in mind to ensure you get the best travel experience. Data last updated March 23, 2026.
Discover carefully curated flight deals from Mississippi to Missouri that have cost, travel time, and layovers in mind to ensure you get the best travel experience. Data last updated March 23, 2026.
This Delta deal was found by Cheapflights users on 3/22. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 4/215:55 pm
GPT
- MCI
1 stop5h 55m
Delta
Tue 4/285:12 pm
MCI
- GPT
1 stop5h 01m
Delta
Deal found 3/22![Delta logo]()
$277
This United Airlines deal was found by Cheapflights users on 3/19. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 4/44:26 pm
GPT
- STL
1 stop6h 02m
United Airlines
Wed 4/89:10 am
STL
- GPT
2 stops10h 43m
United Airlines
Deal found 3/19![United Airlines logo]()
$290
This Southwest deal was found by Cheapflights users on 3/18. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 4/167:20 pm
MEM
- MCI
1 stop4h 30m
Southwest
Tue 4/215:30 am
MCI
- MEM
2 stops7h 15m
Southwest
Deal found 3/18![Southwest logo]()
$310
This American Airlines deal was found by Cheapflights users on 3/22. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 4/305:40 am
BTR
- MCI
1 stop4h 35m
American Airlines
Sun 5/35:30 am
MCI
- BTR
1 stop4h 32m
American Airlines
Deal found 3/22![American Airlines logo]()
$325
This Kiwi.com deal was found by Cheapflights users on 3/18. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 4/179:17 pm
MEM
- MCI
2 stops16h 49m
Multiple Airlines
Sun 4/198:44 am
MCI
- MEM
1 stop10h 10m
Multiple Airlines
Deal found 3/18![Multiple Airlines logo]()
$341
This Delta deal was found by Cheapflights users on 3/19. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 4/75:57 pm
GPT
- STL
1 stop6h 01m
Delta
Tue 4/141:02 pm
STL
- GPT
1 stop4h 06m
Delta
Deal found 3/19![Delta logo]()
$285
This Southwest deal was found by Cheapflights users on 3/20. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 5/186:20 pm
MEM
- MCI
1 stop5h 15m
Southwest
Wed 5/202:55 pm
MCI
- MEM
2 stops6h 50m
Southwest
Deal found 3/20![Southwest logo]()
$310
This Delta deal was found by Cheapflights users on 3/19. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 4/75:57 pm
GPT
- STL
1 stop6h 01m
Delta
Thu 4/97:03 am
STL
- GPT
1 stop6h 57m
Delta
Deal found 3/19![Delta logo]()
$285
This American Airlines deal was found by Cheapflights users on 3/20. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 4/76:32 pm
BTR
- STL
1 stop4h 27m
American Airlines
Sun 4/125:20 am
STL
- BTR
1 stop4h 42m
American Airlines
Deal found 3/20![American Airlines logo]()
$325
This United Airlines deal was found by Cheapflights users on 3/22. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 4/76:09 pm
BTR
- STL
1 stop4h 19m
United Airlines
Sat 4/1111:15 am
STL
- BTR
2 stops9h 59m
United Airlines
Deal found 3/22![United Airlines logo]()
$330
This American Airlines deal was found by Cheapflights users on 3/20. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 4/82:33 pm
BTR
- STL
2 stops7h 44m
American Airlines
Thu 4/95:20 am
STL
- BTR
1 stop4h 42m
American Airlines
Deal found 3/20![American Airlines logo]()
$330
This Delta deal was found by Cheapflights users on 3/19. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 4/136:39 pm
MEM
- MCI
1 stop4h 22m
Delta
Wed 4/153:03 pm
MCI
- MEM
1 stop5h 56m
Delta
Deal found 3/19![Delta logo]()
$305
This Kiwi.com deal was found by Cheapflights users on 3/20. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 5/3111:59 am
MEM
- STL
1 stop20h 56m
Multiple Airlines
Mon 6/15:27 pm
STL
- MEM
2 stops22h 13m
Multiple Airlines
Deal found 3/20![Multiple Airlines logo]()
$370
This United Airlines deal was found by Cheapflights users on 3/21. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 4/55:00 am
BTR
- STL
1 stop4h 25m
United Airlines
Thu 4/96:00 am
STL
- BTR
1 stop7h 25m
United Airlines
Deal found 3/21![United Airlines logo]()
$338
This Southwest deal was found by Cheapflights users on 3/19. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 5/66:30 am
JAN
- MCI
1 stop4h 20m
Southwest
Mon 5/1111:15 am
MCI
- JAN
1 stop9h 45m
Southwest
Deal found 3/19![Southwest logo]()
$357
This American Airlines deal was found by Cheapflights users on 3/19. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 4/46:00 am
GPT
- STL
2 stops11h 13m
American Airlines
Wed 4/82:33 pm
STL
- GPT
2 stops9h 25m
American Airlines
Deal found 3/19![American Airlines logo]()
$332
This United Airlines deal was found by Cheapflights users on 3/19. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 4/212:45 pm
MEM
- MCI
1 stop7h 14m
United Airlines
Sat 4/256:15 am
MCI
- MEM
1 stop4h 39m
United Airlines
Deal found 3/19![United Airlines logo]()
$345
This Delta deal was found by Cheapflights users on 3/19. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 5/263:48 pm
BTR
- STL
1 stop5h 41m
Delta
Thu 5/287:15 am
STL
- BTR
1 stop5h 34m
Delta
Deal found 3/19![Delta logo]()
$317
This Southwest deal was found by Cheapflights users on 3/19. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 5/85:45 am
JAN
- MCI
2 stops7h 35m
Southwest
Mon 5/1112:05 pm
MCI
- JAN
2 stops7h 00m
Southwest
Deal found 3/19![Southwest logo]()
$377
This American Airlines deal was found by Cheapflights users on 3/21. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 4/75:00 am
GPT
- STL
1 stop6h 37m
American Airlines
Fri 4/106:55 pm
STL
- GPT
1 stop5h 03m
American Airlines
Deal found 3/21![American Airlines logo]()
$352
This United Airlines deal was found by Cheapflights users on 3/18. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 8/295:15 pm
GPT
- MCI
1 stop5h 18m
United Airlines
Wed 9/28:30 am
MCI
- GPT
1 stop4h 56m
United Airlines
Deal found 3/18![United Airlines logo]()
$357
This Delta deal was found by Cheapflights users on 3/21. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 4/247:08 pm
BTR
- MCI
1 stop4h 42m
Delta
Mon 5/43:04 pm
MCI
- BTR
1 stop6h 52m
Delta
Deal found 3/21![Delta logo]()
$325
This Kiwi.com deal was found by Cheapflights users on 3/20. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 5/1011:59 am
MEM
- STL
1 stop20h 56m
Multiple Airlines
Fri 5/158:08 pm
STL
- MEM
2 stops22h 15m
Multiple Airlines
Deal found 3/20![Multiple Airlines logo]()
$433
This Southwest deal was found by Cheapflights users on 3/21. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 7/2912:20 pm
JAN
- MCI
2 stops6h 55m
Southwest
Wed 8/51:25 pm
MCI
- JAN
1 stop4h 40m
Southwest
Deal found 3/21![Southwest logo]()
$392
This American Airlines deal was found by Cheapflights users on 3/19. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 5/267:36 pm
BTR
- STL
1 stop4h 23m
American Airlines
Thu 5/286:00 am
STL
- BTR
2 stops7h 48m
American Airlines
Deal found 3/19![American Airlines logo]()
$357
This Delta deal was found by Cheapflights users on 3/20. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 4/74:00 pm
BTR
- STL
1 stop5h 06m
Delta
Sun 4/126:00 am
STL
- BTR
1 stop6h 51m
Delta
Deal found 3/20![Delta logo]()
$325
This United Airlines deal was found by Cheapflights users on 3/20. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 4/44:26 pm
GPT
- MCI
1 stop6h 04m
United Airlines
Wed 4/88:00 am
MCI
- GPT
2 stops11h 53m
United Airlines
Deal found 3/20![United Airlines logo]()
$370
This Kiwi.com deal was found by Cheapflights users on 3/21. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 4/39:17 pm
MEM
- STL
2 stops12h 31m
Multiple Airlines
Sat 4/48:16 pm
STL
- MEM
1 stop19h 20m
Multiple Airlines
Deal found 3/21![Multiple Airlines logo]()
$450
This Southwest deal was found by Cheapflights users on 3/21. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 7/135:10 am
JAN
- MCI
2 stops9h 20m
Southwest
Sun 7/193:30 pm
MCI
- JAN
1 stop6h 30m
Southwest
Deal found 3/21![Southwest logo]()
$392
This Delta deal was found by Cheapflights users on 3/22. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 4/77:05 pm
BTR
- STL
1 stop4h 53m
Delta
Sat 4/116:00 am
STL
- BTR
1 stop6h 51m
Delta
Deal found 3/22![Delta logo]()
$325
Last-minute flights from Mississippi to MissouriDiscover last-minute flight deals from Mississippi to Missouri. Data last updated March 23, 2026 and is based on user searches.
Discover last-minute flight deals from Mississippi to Missouri. Data last updated March 23, 2026 and is based on user searches.
This CheapOair deal was found by Cheapflights users on 3/19. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure CheapOair is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 3/268:30 pm
MEM
- STL
1 stop14h 49m
Frontier
Sat 4/118:16 pm
STL
- MEM
1 stop19h 20m
Frontier
Deal found 3/19![Frontier logo]()
$251
This Frontier deal was found by Cheapflights users on 3/18. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Frontier is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 4/28:30 pm
MEM
- STL
1 stop14h 57m
Frontier
Sun 4/511:21 am
STL
- MEM
1 stop5h 48m
Frontier
Deal found 3/18![Frontier logo]()
$250
This United Airlines deal was found by Cheapflights users on 3/19. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 4/44:26 pm
GPT
- STL
1 stop6h 02m
United Airlines
Wed 4/89:10 am
STL
- GPT
2 stops10h 43m
United Airlines
Deal found 3/19![United Airlines logo]()
$290
This Delta deal was found by Cheapflights users on 3/19. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 4/75:57 pm
GPT
- STL
1 stop6h 01m
Delta
Tue 4/141:02 pm
STL
- GPT
1 stop4h 06m
Delta
Deal found 3/19![Delta logo]()
$285
This Orbitz deal was found by Cheapflights users on 3/19. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Orbitz is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 4/124:31 pm
MEM
- STL
1 stop17h 17m
Frontier
Sun 4/1911:16 am
STL
- MEM
1 stop6h 26m
Frontier
Deal found 3/19![Frontier logo]()
$180
This Delta deal was found by Cheapflights users on 3/20. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 4/135:59 pm
MEM
- MCI
1 stop5h 51m
Delta
Wed 4/153:03 pm
MCI
- MEM
1 stop5h 56m
Delta
Deal found 3/20![Delta logo]()
$305
This Southwest deal was found by Cheapflights users on 3/20. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 4/143:25 pm
MEM
- MCI
1 stop3h 25m
Southwest
Mon 4/205:15 pm
MCI
- MEM
1 stop5h 45m
Southwest
Deal found 3/20![Southwest logo]()
$300
This Southwest deal was found by Cheapflights users on 3/18. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 4/167:20 pm
MEM
- MCI
1 stop4h 30m
Southwest
Tue 4/215:30 am
MCI
- MEM
2 stops7h 15m
Southwest
Deal found 3/18![Southwest logo]()
$310
This Kiwi.com deal was found by Cheapflights users on 3/19. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 4/196:42 pm
MEM
- STL
1 stop12h 08m
Multiple Airlines
Wed 4/228:23 pm
STL
- MEM
2 stops34h 52m
Multiple Airlines
Deal found 3/19![Multiple Airlines logo]()
$293
This Kiwi.com deal was found by Cheapflights users on 3/19. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 4/196:42 pm
MEM
- STL
1 stop12h 08m
Frontier
Wed 4/228:23 pm
STL
- MEM
1 stop20h 53m
Frontier
Deal found 3/19![Frontier logo]()
$302
This Delta deal was found by Cheapflights users on 3/22. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 4/215:55 pm
GPT
- MCI
1 stop5h 55m
Delta
Tue 4/285:12 pm
MCI
- GPT
1 stop5h 01m
Delta
Deal found 3/22![Delta logo]()
$277
This American Airlines deal was found by Cheapflights users on 3/22. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 4/257:37 pm
GPT
- MCI
1 stop4h 30m
American Airlines
Sun 4/265:30 am
MCI
- GPT
1 stop5h 03m
American Airlines
Deal found 3/22![American Airlines logo]()
$303
One-way flights from Mississippi to MissouriSearch for one-way flight options from Mississippi to Missouri. Find affordable one-way fares based on user searches. Data last updated March 23, 2026.
Search for one-way flight options from Mississippi to Missouri. Find affordable one-way fares based on user searches. Data last updated March 23, 2026.
This Expedia deal was found by Cheapflights users on 3/22. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Expedia is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 4/124:31 pm
MEM
- STL
1 stop17h 17m
Frontier
Deal found 3/22![Frontier logo]()
$76
This Southwest deal was found by Cheapflights users on 3/23. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 5/53:25 pm
MEM
- MCI
1 stop3h 25m
Southwest
Deal found 3/23![Southwest logo]()
$112
This Priceline deal was found by Cheapflights users on 3/20. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Priceline is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 4/22:47 pm
MEM
- MCI
1 stop5h 14m
Frontier
Deal found 3/20![Frontier logo]()
$115
This American Airlines deal was found by Cheapflights users on 3/23. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 4/156:00 am
JAN
- MCI
1 stop8h 56m
American Airlines
Deal found 3/23![American Airlines logo]()
$126
This American Airlines deal was found by Cheapflights users on 3/20. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 4/226:40 am
MEM
- STL
1 stop10h 01m
American Airlines
Deal found 3/20![American Airlines logo]()
$137
This Delta deal was found by Cheapflights users on 3/21. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 4/188:21 am
MEM
- MCI
1 stop4h 40m
Delta
Deal found 3/21![Delta logo]()
$138
This United Airlines deal was found by Cheapflights users on 3/22. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 4/254:26 pm
GPT
- STL
1 stop6h 02m
United Airlines
Deal found 3/22![United Airlines logo]()
$139
This Southwest deal was found by Cheapflights users on 3/21. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 4/1812:15 pm
MEM
- MCI
2 stops8h 20m
Southwest
Deal found 3/21![Southwest logo]()
$143
This American Airlines deal was found by Cheapflights users on 3/23. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 4/238:02 pm
JAN
- MCI
1 stop4h 05m
American Airlines
Deal found 3/23![American Airlines logo]()
$152
This Delta deal was found by Cheapflights users on 3/23. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 9/176:00 am
BTR
- STL
1 stop6h 53m
Delta
Deal found 3/23![Delta logo]()
$159
This Delta deal was found by Cheapflights users on 3/20. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 4/154:00 pm
BTR
- STL
1 stop5h 19m
Delta
Deal found 3/20![Delta logo]()
$163
This American Airlines deal was found by Cheapflights users on 3/23. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 4/157:06 am
BTR
- STL
2 stops8h 54m
American Airlines
Deal found 3/23![American Airlines logo]()
$168
Find flight deals from Mississippi to Missouri
Keep the following information in mind while searching for Mississippi to Missouri flight deals. Data was last updated March 23, 2026.
Most accurate provider | FlightHub 3 stars |
|---|---|
Most trusted provider | FlightHub 3 stars |
Round-trip from | $180 (Orbitz) |
One-way from | $76 (Expedia) |
Popular in | May |
Cheapest in | February |
Average price | $577 |
Cheapflights Fare Finder
Customize your flight search to find flights from Mississippi to Missouri that fit within your specific budget. Explore options based on user searches and filter the results based on your desired price range. Find flights that match your budget for a cost-effective journey. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated March 23, 2026.
Use the filters below to find and compare flights from Mississippi to Missouri that are best for you.
Fly from
Fly to
Route
Depart
Return
Cheapest round-trip
GulfportKansas City
GPT - MCI
GPTMCI
Gulfport Biloxi Regional
Tue 4/21
5:55 pm-11:50 pm
1 stop5h 55m
Kansas City
Tue 4/28
5:12 pm-10:13 pm
1 stop5h 01m
$277
GulfportSt. Louis
GPT - STL
GPTSTL
Gulfport Biloxi Regional
Tue 4/7
5:57 pm-11:58 pm
1 stop6h 01m
Lambert-St Louis
Tue 4/14
1:02 pm-5:08 pm
1 stop4h 06m
$285
GulfportSt. Louis
GPT - STL
GPTSTL
Gulfport Biloxi Regional
Tue 4/7
5:57 pm-11:58 pm
1 stop6h 01m
Lambert-St Louis
Thu 4/9
7:03 am-2:00 pm
1 stop6h 57m
$285
GulfportSt. Louis
GPT - STL
GPTSTL
Gulfport Biloxi Regional
Sat 4/4
4:26 pm-10:28 pm
1 stop6h 02m
Lambert-St Louis
Wed 4/8
9:10 am-7:53 pm
2 stops10h 43m
$290
MemphisKansas City
MEM - MCI
MEMMCI
Memphis
Mon 4/13
6:39 pm-11:01 pm
1 stop4h 22m
Kansas City
Wed 4/15
3:03 pm-8:59 pm
1 stop5h 56m
$305
MemphisKansas City
MEM - MCI
MEMMCI
Memphis
Thu 4/16
7:20 pm-11:50 pm
1 stop4h 30m
Kansas City
Tue 4/21
5:30 am-12:45 pm
2 stops7h 15m
$310
MemphisKansas City
MEM - MCI
MEMMCI
Memphis
Mon 5/18
6:20 pm-11:35 pm
1 stop5h 15m
Kansas City
Wed 5/20
2:55 pm-9:45 pm
2 stops6h 50m
$310
Baton RougeSt. Louis
BTR - STL
BTRSTL
Baton Rouge Ryan
Tue 5/26
3:48 pm-9:29 pm
1 stop5h 41m
Lambert-St Louis
Thu 5/28
7:15 am-12:49 pm
1 stop5h 34m
$317
Quickest round-trip
Baton RougeKansas City
BTR - MCI
BTRMCI
Baton Rouge Ryan
Thu 4/30
5:40 am-10:15 am
1 stop4h 35m
Kansas City
Sun 5/3
5:30 am-10:02 am
1 stop4h 32m
$325
Baton RougeSt. Louis
BTR - STL
BTRSTL
Baton Rouge Ryan
Tue 4/7
6:32 pm-10:59 pm
1 stop4h 27m
Lambert-St Louis
Sun 4/12
5:20 am-10:02 am
1 stop4h 42m
$325
Showing 1-10 of 60 resultsSorted by cheapest first
Best time to book a flight from Mississippi to Missouri
Have a flexible travel schedule? Discover the best time to fly to Missouri from Mississippi with our price prediction graph.
MEM-STL
GPT-MCI
GPT-STL
MEM-MCI
JAN-MCI
Estimated round-trip price
Rates are based on past data. Find the cheapest month and day to book your flight based on your travel requirements, then search for cheap deals.
Cheapflights Insights
Everything you need to know about your flight from Mississippi to Missouri
USMS-USMO
MEM-STL
GPT-MCI
GPT-STL
MEM-MCI
What is the cheapest month to book a flight from Mississippi to Missouri?
Currently, August is the cheapest month in which you can book a flight from Mississippi to Missouri (average of $216). Flying from Mississippi to Missouri in December is currently the most expensive (average of $390). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.
How much does it cost to fly round-trip from Mississippi to Missouri?
Reviews of airlines servicing Missouri
Get insights into the airlines that provide service to Missouri. Read reviews, discover amenities, and learn about the overall travel experience offered by airlines. Use this information to make informed decisions when choosing an airline for your flight to Missouri. Reviews last updated March 23, 2026.
Get a feel of what it's like to fly with Southwest,Delta, andAmerican Airlines from Mississippi to Missouri by reading reviews from past customers. You can also see how each airline stacks up in terms of entertainment options, comfort, food, crew/service, and boarding process.
Overall
8.0
Comfort
8.0
Food
7.0
Boarding
8.1
Entertainment
7.5
Crew
8.6
Reviews
1 / 20
2.0
MediocreDominic,Mar 2026
MCO - SMF
Overall
8.0
Comfort
8.0
Food
7.0
Boarding
8.1
Entertainment
7.5
Crew
8.6
Reviews
1 / 20
2.0
MediocreDominic,Mar 2026
MCO - SMF
Overall
8.0
Comfort
8.0
Food
7.0
Boarding
8.1
Entertainment
7.5
Crew
8.6
Reviews
1 / 20
2.0
MediocreDominic,Mar 2026
MCO - SMF
Overall
8.0
Comfort
8.0
Food
7.0
Boarding
8.1
Entertainment
7.5
Crew
8.6
Reviews
1 / 20
2.0
MediocreDominic,Mar 2026
MCO - SMF
Related info for your journey
Find useful and relevant information for your journey from Mississippi to Missouri. Access travel guides, tips, and recommendations to enhance your travel experience. Get information about local attractions, weather, transportation options, and more.
Browse thousands of different options on Cheapflights for your next trip
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Alternative routes for Mississippi to Missouri
See prices for flight routes from nearby airports that may be better suited for you.
Complete your trip
Complete your trip to Missouri by adding a car rental and/or hotel reservation to your travel itinerary.
Search flights from Mississippi to Missouri by cabin class
Find flights from Mississippi to Missouri, based on your preferred cabin class, be it economy, premium economy, business, or first class.
Mississippi and Missouri flights
Browse other Mississippi and Missouri flight options. Last updated on March 23, 2026.
Popular flight searches
Check out other popular destinations found by fellow travelers in 2026
Find a return flight route from Missouri
Find the right flight back to Mississippi after your stay in Missouri
Mississippi to Missouri flights
Consider these flights traveling from Mississippi to Missouri.
Top 3 airlines flying from Mississippi to Missouri
Discover the top 3 airlines that operate flights from Mississippi to Missouri. Compare their services, reliability, and customer satisfaction ratings to choose the airline that best suits your travel preferences and needs. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated March 23, 2026.
| Airline | Cheapest | Average | Flexibility | On-time |
|---|---|---|---|---|
| Cheapest$216 | Average$432 | FlexibilityNo cancel fee | On-timeN/A | |
| Cheapest$246 | Average$373 | FlexibilityNo cancel fee | On-time71% | |
| Cheapest$271 | Average$331 | FlexibilityNo cancel fee | On-time63% |