How long is the flight from Mississippi to Missouri?

Departing from Mississippi to Missouri will take you 4h 25m. The distance from Mississippi to Missouri is about 638 mi. When browsing for deals, the options you’ll see will be for both nonstop flights and flights with stops.

What are the cheapest airlines to fly from Mississippi to Missouri one-way?

The cheapest airline one-way is American Airlines, with whom users have recently found tickets for as low as $99. However, be on the lookout for offers from Delta and Southwest, as they are both options that can get you from Mississippi to Missouri for a low price.

In terms of precipitation, rainfall in Missouri ranges from 2.2 - 4.7 inches per month. May is typically the wettest month, when rainfall can reach 4.7 in. February is typically the driest time to visit Missouri when rainfall is around 2.2 in.

If weather is an important factor for your trip to Missouri, use this chart to help with planning. For those seeking warmer temperatures, July is the ideal time of year to visit, when temperatures reach an average of 80.6 F. Travelers looking to avoid the cold should look outside of January, when temperatures are typically at their lowest (around 32.0 F).

Can I find deals for flights from Mississippi to Missouri that include hotel bookings?

Yes. In addition to deals on Mississippi to Missouri flights, Cheapflights offers vacation packages that include both flights and hotel.

How can I find direct flights from Mississippi to Missouri?

After entering your origin and destination, apply the non-stop filter on the search result page to find direct flights from Mississippi to Missouri.

Can I find deals for business class flights from Mississippi to Missouri?

Yes. Cheapflights offers flight deals from Mississippi to Missouri by cabin class. In addition to browsing deals, you can also filter by cabin class on the search results page after making a search.

$90+ Flights from Mississippi to Missouri

Q: How much does it cost to fly round-trip from Mississippi to Missouri?

Airfare is below average for this route at the moment. Mississippi to Missouri flights typically cost between $446 and $576 in January. The cheapest round-trip price found within the last 3 days was $325 on United Airlines (Jan 17-Jan 20).

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Cheap flight deals from Mississippi to Missouri

Cheapest flights from Mississippi to Missouri
Explore the most affordable flight options available from Mississippi to Missouri. Find the lowest fares from popular airlines and budget airlines, with prices last updated on December 18, 2025.

Thu 12/256:00 amJAN - MCI

1 stop5h 36mDelta

Thu 1/14:12 pmMCI - JAN

1 stop6h 53mDelta

Deal found 12/16

$255

Wed 12/315:01 pmMEM - MCI

1 stop6h 55mDelta

Wed 1/76:15 amMCI - MEM

1 stop5h 28mDelta

Deal found 12/17

$259

Wed 12/245:01 pmMEM - MCI

1 stop6h 58mDelta

Thu 12/253:29 pmMCI - MEM

1 stop6h 52mDelta

Deal found 12/16

$261

Wed 12/317:05 amMEM - MCI

2 stops9h 24mAmerican Airlines

Wed 1/712:31 pmMCI - MEM

1 stop8h 01mAmerican Airlines

Deal found 12/17

$267

Mon 12/295:10 amBTR - STL

1 stop4h 39mUnited Airlines

Fri 1/26:00 amSTL - BTR

1 stop5h 25mUnited Airlines

Deal found 12/17

$309

Wed 12/316:20 amMOB - STL

1 stop6h 01mDelta

Sun 1/47:02 pmSTL - MOB

1 stop4h 09mDelta

Deal found 12/16

$319

Wed 12/3111:25 amMEM - MCI

2 stops10h 25mUnited Airlines

Wed 1/78:00 amMCI - MEM

2 stops8h 09mUnited Airlines

Deal found 12/17

$329

Fri 12/264:34 pmBTR - STL

1 stop7h 21mAmerican Airlines

Mon 12/295:16 amSTL - BTR

1 stop4h 23mAmerican Airlines

Deal found 12/15

$339

Thu 12/185:53 pmBTR - MCI

1 stop5h 01mAmerican Airlines

Sat 12/205:05 amMCI - BTR

1 stop4h 34mAmerican Airlines

Deal found 12/16

$369

Thu 12/1812:11 pmBTR - MCI

2 stops9h 39mUnited Airlines

Sat 12/203:00 pmMCI - BTR

1 stop6h 18mUnited Airlines

Deal found 12/16

$374

Sat 12/2010:09 amBTR - STL

1 stop7h 01mAmerican Airlines

Tue 12/305:00 amSTL - BTR

1 stop7h 29mAmerican Airlines

Deal found 12/17

$374

Mon 12/297:11 amBTR - STL

2 stops9h 12mAmerican Airlines

Sun 1/45:16 amSTL - BTR

1 stop4h 23mAmerican Airlines

Deal found 12/17

$380

Best flights from Mississippi to Missouri
Discover carefully curated flight deals from Mississippi to Missouri that have cost, travel time, and layovers in mind to ensure you get the best travel experience. Data last updated December 18, 2025.

Thu 1/155:51 pmBTR - STL

1 stop5h 48mDelta

Sun 1/187:10 amSTL - BTR

1 stop6h 20mDelta

Deal found 12/17

$209

Thu 2/198:09 pmMEM - MCI

1 stop21h 57mFrontier

Sun 2/2210:14 amMCI - MEM

1 stop8h 05mFrontier

Deal found 12/15

$212

Thu 1/2911:44 amMEM - STL

1 stop22h 39mMultiple Airlines

Sun 2/112:03 pmSTL - MEM

1 stop26h 14mMultiple Airlines

Deal found 12/16

$223

Fri 1/166:47 pmBTR - MCI

1 stop4h 25mAmerican Airlines

Sun 1/185:49 pmMCI - BTR

1 stop5h 07mAmerican Airlines

Deal found 12/17

$239

Wed 2/116:10 amMEM - MCI

2 stops6h 10mSouthwest

Wed 2/257:00 amMCI - MEM

2 stops7h 05mSouthwest

Deal found 12/17

$267

Fri 1/97:00 amBTR - MCI

1 stop4h 50mUnited Airlines

Tue 1/1310:00 amMCI - BTR

2 stops9h 33mUnited Airlines

Deal found 12/16

$274

Thu 1/1511:44 amMEM - STL

1 stop10h 50mMultiple Airlines

Sun 1/185:11 pmSTL - MEM

1 stop17h 38mMultiple Airlines

Deal found 12/17

$223

Thu 1/18:07 pmMEM - STL

1 stop13h 55mFrontier

Sun 1/410:57 amSTL - MEM

1 stop4h 11mFrontier

Deal found 12/15

$242

Thu 1/811:44 amMEM - MCI

2 stops22h 47mMultiple Airlines

Sun 1/118:23 pmMCI - MEM

1 stop17h 41mMultiple Airlines

Deal found 12/17

$224

Tue 1/205:22 pmMEM - MCI

1 stop6h 29mDelta

Wed 1/218:05 amMCI - MEM

1 stop4h 47mDelta

Deal found 12/16

$257

Thu 1/15:53 pmBTR - STL

1 stop5h 03mAmerican Airlines

Mon 1/52:04 pmSTL - BTR

1 stop5h 53mAmerican Airlines

Deal found 12/16

$264

Wed 1/2111:44 amMEM - STL

1 stop11h 49mMultiple Airlines

Thu 1/225:42 pmSTL - MEM

2 stops20h 35mMultiple Airlines

Deal found 12/16

$234

Wed 12/315:01 pmMEM - MCI

1 stop6h 55mDelta

Wed 1/76:15 amMCI - MEM

1 stop5h 28mDelta

Deal found 12/17

$259

Wed 12/317:05 amMEM - MCI

2 stops9h 24mAmerican Airlines

Wed 1/712:31 pmMCI - MEM

1 stop8h 01mAmerican Airlines

Deal found 12/17

$267

Fri 1/163:30 pmBTR - MCI

1 stop7h 10mUnited Airlines

Sun 1/185:45 amMCI - BTR

2 stops7h 32mUnited Airlines

Deal found 12/17

$309

Fri 2/611:44 amMEM - MCI

2 stops22h 47mMultiple Airlines

Sun 2/811:26 amMCI - MEM

1 stop8h 02mMultiple Airlines

Deal found 12/16

$236

Tue 1/1312:34 pmMOB - MCI

1 stop4h 23mDelta

Tue 1/201:22 pmMCI - MOB

1 stop4h 54mDelta

Deal found 12/16

$269

Fri 1/167:07 amBTR - STL

1 stop7h 57mAmerican Airlines

Mon 1/193:37 pmSTL - BTR

1 stop7h 19mAmerican Airlines

Deal found 12/17

$269

Mon 12/295:10 amBTR - STL

1 stop4h 39mUnited Airlines

Fri 1/26:00 amSTL - BTR

1 stop5h 25mUnited Airlines

Deal found 12/17

$309

Thu 2/194:52 pmMEM - MCI

2 stops17h 38mMultiple Airlines

Sun 2/2210:14 amMCI - MEM

1 stop8h 05mMultiple Airlines

Deal found 12/15

$238

Sun 1/255:35 amJAN - MCI

1 stop4h 10mSouthwest

Thu 1/296:15 amMCI - JAN

2 stops8h 25mSouthwest

Deal found 12/16

$354

Fri 1/306:08 pmGPT - STL

1 stop5h 29mDelta

Sun 2/17:10 amSTL - GPT

1 stop6h 41mDelta

Deal found 12/16

$269

Wed 1/75:31 pmBTR - STL

1 stop5h 41mAmerican Airlines

Wed 1/2111:05 amSTL - BTR

2 stops9h 54mAmerican Airlines

Deal found 12/16

$274

Wed 1/149:30 amBTR - MCI

1 stop7h 23mUnited Airlines

Sun 1/188:00 amMCI - BTR

2 stops9h 53mUnited Airlines

Deal found 12/16

$314

Mon 1/263:40 pmMEM - MCI

1 stop24h 29mMultiple Airlines

Wed 1/285:04 pmMCI - MEM

1 stop17h 45mMultiple Airlines

Deal found 12/15

$240

Fri 1/92:19 pmBTR - MCI

1 stop5h 43mDelta

Tue 1/135:50 amMCI - BTR

1 stop7h 40mDelta

Deal found 12/16

$269

Wed 1/218:15 amMEM - STL

2 stops10h 30mSouthwest

Thu 1/226:05 amSTL - MEM

2 stops7h 50mSouthwest

Deal found 12/16

$362

Fri 1/301:45 pmGPT - STL

2 stops8h 06mAmerican Airlines

Sun 2/16:00 amSTL - GPT

2 stops10h 55mAmerican Airlines

Deal found 12/16

$279

Sat 1/177:00 amJAN - MCI

1 stop7h 04mUnited Airlines

Tue 1/208:05 amMCI - JAN

1 stop5h 17mUnited Airlines

Deal found 12/17

$325

Fri 3/276:59 pmBTR - MCI

1 stop5h 07mDelta

Sun 3/298:10 amMCI - BTR

1 stop4h 41mDelta

Deal found 12/16

$269

Last-minute flights from Mississippi to Missouri
Discover last-minute flight deals from Mississippi to Missouri. Data last updated December 18, 2025 and is based on user searches.

Thu 12/256:00 amJAN - MCI

1 stop5h 36mDelta

Thu 1/14:12 pmMCI - JAN

1 stop6h 53mDelta

Deal found 12/16

$255

Thu 1/18:07 pmMEM - STL

1 stop13h 55mFrontier

Sun 1/410:57 amSTL - MEM

1 stop4h 11mFrontier

Deal found 12/15

$242

Thu 1/811:44 amMEM - MCI

2 stops22h 47mMultiple Airlines

Sun 1/118:23 pmMCI - MEM

1 stop17h 41mMultiple Airlines

Deal found 12/17

$224

Fri 1/91:21 pmMEM - MCI

1 stop10h 12mMultiple Airlines

Mon 1/1211:26 amMCI - MEM

2 stops23h 23mMultiple Airlines

Deal found 12/16

$252

Sun 1/1111:44 amMEM - STL

1 stop20h 21mMultiple Airlines

Fri 1/238:22 pmSTL - MEM

2 stops14h 27mMultiple Airlines

Deal found 12/16

$256

Wed 1/1411:44 amMEM - MCI

1 stop28h 25mSpirit Airlines

Mon 1/1911:26 amMCI - MEM

2 stops23h 23mSpirit Airlines

Deal found 12/16

$245

Thu 1/155:51 pmBTR - STL

1 stop5h 48mDelta

Sun 1/187:10 amSTL - BTR

1 stop6h 20mDelta

Deal found 12/17

$209

Thu 1/1511:44 amMEM - STL

1 stop10h 50mMultiple Airlines

Sun 1/185:11 pmSTL - MEM

1 stop17h 38mMultiple Airlines

Deal found 12/17

$223

Fri 1/166:47 pmBTR - MCI

1 stop4h 25mAmerican Airlines

Sun 1/185:49 pmMCI - BTR

1 stop5h 07mAmerican Airlines

Deal found 12/17

$239

Wed 1/2111:44 amMEM - STL

1 stop11h 49mMultiple Airlines

Thu 1/225:42 pmSTL - MEM

1 stop21h 08mMultiple Airlines

Deal found 12/16

$216

Mon 1/263:40 pmMEM - MCI

1 stop24h 29mMultiple Airlines

Wed 1/285:04 pmMCI - MEM

1 stop17h 45mMultiple Airlines

Deal found 12/15

$240

Mon 1/261:21 pmMEM - MCI

1 stop10h 12mMultiple Airlines

Tue 1/275:04 pmMCI - MEM

1 stop17h 45mMultiple Airlines

Deal found 12/17

$251

One-way flights from Mississippi to Missouri
Search for one-way flight options from Mississippi to Missouri. Find affordable one-way fares based on user searches. Data last updated December 18, 2025.

Wed 1/2111:44 amMEM - STL

1 stop11h 49mMultiple Airlines

Deal found 12/16

$90

Tue 1/1311:44 amMEM - MCI

1 stop28h 25mSpirit Airlines

Deal found 12/16

$121

Wed 1/2811:44 amMEM - STL

1 stop11h 49mMultiple Airlines

Deal found 12/16

$123

Sat 1/179:55 amMEM - MCI

1 stop4h 27mUnited Airlines

Deal found 12/16

$129

Tue 1/136:35 amMEM - MCI

2 stops7h 55mAmerican Airlines

Deal found 12/16

$134

Sat 1/1711:44 amMEM - MCI

2 stops22h 47mSpirit Airlines

Deal found 12/16

$140

Tue 1/1311:44 amMEM - MCI

3 stops56h 04mMultiple Airlines

Deal found 12/16

$157

Sat 1/1711:44 amMEM - MCI

3 stops54h 34mMultiple Airlines

Deal found 12/16

$165

Wed 1/286:10 amMEM - STL

2 stops7h 25mSouthwest

Deal found 12/16

$171

Sat 1/171:40 pmMEM - MCI

2 stops7h 25mSouthwest

Deal found 12/16

$171

Wed 1/2811:44 amMEM - MCI

3 stops22h 47mMultiple Airlines

Deal found 12/16

$185

Wed 1/286:00 amMOB - MCI

1 stop6h 17mDelta

Deal found 12/17

$237

Find flight deals from Mississippi to Missouri

Most accurate provider	eDreams 3 stars
Most trusted provider	eDreams 3 stars
Round-trip from	$209 (Delta)
One-way from	$90 (Kiwi.com)
Popular in	May
Cheapest in	February
Average price	$534

Provider with most accurate pricing for Jackson-Evers Intl-Lambert-St Louis flight deals.

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Provider most trusted by Cheapflights users for Jackson-Evers Intl-Lambert-St Louis flights.

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From Mississippi to Missouri

Search Deals

One-way flight from Mississippi to Missouri

Search Deals

Highest demand for flights based on searches. 7% potential increase in price ($32 potential increase over avg. RT price).

Search Deals

Cheapest flight prices on average. 5% potential price decrease ($22 potential savings vs. average RT price).

Search Deals

Average for round-trip flights in December 2025

Search Deals

Cheapflights Fare Finder

Use the filters below to find and compare flights from Mississippi to Missouri that are best for you.

Fly from

Fly to

Route

Depart

Return

Price

Baton RougeSt. Louis

BTR - STL

BTRSTL

Baton Rouge Ryan

Thu 1/15

5:51 pm-11:39 pm

1 stop5h 48m

Lambert-St Louis

Sun 1/18

7:10 am-1:30 pm

1 stop6h 20m

$209

MemphisKansas City

MEM - MCI

MEMMCI

Memphis

Thu 2/19

8:09 pm-6:06 pm

1 stop21h 57m

Kansas City

Sun 2/22

10:14 am-6:19 pm

1 stop8h 05m

$212

MemphisSt. Louis

MEM - STL

MEMSTL

Memphis

Thu 1/29

11:44 am-10:23 am

1 stop22h 39m

Lambert-St Louis

Sun 2/1

12:03 pm-2:17 pm

1 stop26h 14m

$223

MemphisSt. Louis

MEM - STL

MEMSTL

Memphis

Thu 1/15

11:44 am-10:34 pm

1 stop10h 50m

Lambert-St Louis

Sun 1/18

5:11 pm-10:49 am

1 stop17h 38m

$223

MemphisKansas City

MEM - MCI

MEMMCI

Memphis

Thu 1/8

11:44 am-10:31 am

2 stops22h 47m

Kansas City

Sun 1/11

8:23 pm-2:04 pm

1 stop17h 41m

$224

MemphisSt. Louis

MEM - STL

MEMSTL

Memphis

Wed 1/21

11:44 am-11:33 pm

1 stop11h 49m

Lambert-St Louis

Thu 1/22

5:42 pm-2:17 pm

2 stops20h 35m

$234

MemphisKansas City

MEM - MCI

MEMMCI

Memphis

Fri 2/6

11:44 am-10:31 am

2 stops22h 47m

Kansas City

Sun 2/8

11:26 am-7:28 pm

1 stop8h 02m

$236

MemphisKansas City

MEM - MCI

MEMMCI

Memphis

Thu 2/19

4:52 pm-10:30 am

2 stops17h 38m

Kansas City

Sun 2/22

10:14 am-6:19 pm

1 stop8h 05m

$238

Baton RougeKansas City

BTR - MCI

BTRMCI

Baton Rouge Ryan

Fri 1/16

6:47 pm-11:12 pm

1 stop4h 25m

Kansas City

Sun 1/18

5:49 pm-10:56 pm

1 stop5h 07m

$239

MemphisKansas City

MEM - MCI

MEMMCI

Memphis

Mon 1/26

3:40 pm-4:09 pm

1 stop24h 29m

Kansas City

Wed 1/28

5:04 pm-10:49 am

1 stop17h 45m

$240

Flights are sorted by cheapest round-trip flights first.

Deals found on 12/16

Showing 1-10 of 56 results

...

Best time to book a flight from Mississippi to Missouri

Have a flexible travel schedule? Discover the best time to fly to Missouri from Mississippi with our price prediction graph.

Estimated round-trip price

Rates are based on past data. Find the cheapest month and day to book your flight based on your travel requirements, then search for cheap deals.

Cheapflights Insights

Everything you need to know about your flight from Mississippi to Missouri

What is the cheapest month to book a flight from Mississippi to Missouri?

Currently, December is the cheapest month in which you can book a flight from Mississippi to Missouri (average of $218). Flying from Mississippi to Missouri in March is currently the most expensive (average of $333). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.

What is the cheapest time of day to fly from MS to MO?

It’s typically best to fly out from Mississippi to Missouri in the afternoon. Doing so could potentially save you 17% on the flight price compared to flying in the morning, which is usually more expensive.

How much does it cost to fly round-trip from Mississippi to Missouri?

Reviews of airlines servicing Missouri

Get a feel of what it's like to fly with Southwest, Delta, and American Airlines from Mississippi to Missouri by reading reviews from past customers. You can also see how each airline stacks up in terms of entertainment options, comfort, food, crew/service, and boarding process.

Southwest

7.9

Good

4,250 reviews

Reviews

1 / 20

2.0

Mediocre

Thomas,Dec 2025

SEA - DEN

Plane two hours late in leaving 1:00 pm west coat time got home next day at 2:45am most car rental places are closed and don’t open till 5am

Southwest

7.9

Good

4,250 reviews

Southwest

7.9

Good

4,250 reviews

Reviews

1 / 20

2.0

Mediocre

Thomas,Dec 2025

SEA - DEN

Plane two hours late in leaving 1:00 pm west coat time got home next day at 2:45am most car rental places are closed and don’t open till 5am

Delta

7.9

Good

8,005 reviews

Southwest

7.9

Good

4,250 reviews

Reviews

1 / 20

2.0

Mediocre

Thomas,Dec 2025

SEA - DEN

Plane two hours late in leaving 1:00 pm west coat time got home next day at 2:45am most car rental places are closed and don’t open till 5am

American Airlines

7.2

Good

11,054 reviews

Southwest

7.9

Good

4,250 reviews

Reviews

1 / 20

2.0

Mediocre

Thomas,Dec 2025

SEA - DEN

Plane two hours late in leaving 1:00 pm west coat time got home next day at 2:45am most car rental places are closed and don’t open till 5am

Related info for your journey

How long is the flight from Mississippi to Missouri?
Departing from Mississippi to Missouri will take you 4h 25m. The distance from Mississippi to Missouri is about 638 mi. When browsing for deals, the options you’ll see will be for both nonstop flights and flights with stops.
What are the cheapest airlines to fly from Mississippi to Missouri one-way?
The cheapest airline one-way is American Airlines, with whom users have recently found tickets for as low as $99. However, be on the lookout for offers from Delta and Southwest, as they are both options that can get you from Mississippi to Missouri for a low price.
Can I find deals for flights from Mississippi to Missouri that include hotel bookings?
Yes. In addition to deals on Mississippi to Missouri flights, Cheapflights offers vacation packages that include both flights and hotel.
How can I find direct flights from Mississippi to Missouri?
After entering your origin and destination, apply the non-stop filter on the search result page to find direct flights from Mississippi to Missouri.
Can I find deals for business class flights from Mississippi to Missouri?
Yes. Cheapflights offers flight deals from Mississippi to Missouri by cabin class. In addition to browsing deals, you can also filter by cabin class on the search results page after making a search.
What is the cheapest month to book a flight from Mississippi to Missouri?
Currently, December is the cheapest month in which you can book a flight from Mississippi to Missouri (average of $218). Flying from Mississippi to Missouri in March is currently the most expensive (average of $333). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.

See more FAQs

Browse thousands of different options on Cheapflights for your next trip

Top 3 airlines flying from Mississippi to Missouri

Airline	Cheapest	Average	Flexibility	On-time
Delta	Cheapest$240	Average$383	FlexibilityNo cancel fee	On-timeN/A
American Airlines	Cheapest$246	Average$338	FlexibilityNo cancel fee	On-time71%
Southwest	Cheapest$271	Average$331	FlexibilityNo cancel fee	On-time63%

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$90+ Cheap flights from Mississippi to Missouri

This is the cheapest one-way flight price found by a Cheapflights user in the last 72 hours by searching for a flight departing on 1/21. Fares are subject to change and may not be available on all flights or dates of travel.

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Cheap flight deals from Mississippi to Missouri

Cheapest flights from Mississippi to MissouriExplore the most affordable flight options available from Mississippi to Missouri. Find the lowest fares from popular airlines and budget airlines, with prices last updated on December 18, 2025.

Explore the most affordable flight options available from Mississippi to Missouri. Find the lowest fares from popular airlines and budget airlines, with prices last updated on December 18, 2025.

Find flight deals from Mississippi to Missouri

Keep the following information in mind while searching for Mississippi to Missouri flight deals. Data was last updated December 18, 2025.

Most accurate provider

Most trusted provider

Round-trip from

One-way from

Popular in

Cheapest in

Average price

Cheapflights Fare Finder

Use the filters below to find and compare flights from Mississippi to Missouri that are best for you.

Best time to book a flight from Mississippi to Missouri

Have a flexible travel schedule? Discover the best time to fly to Missouri from Mississippi with our price prediction graph.

Cheapflights Insights

Everything you need to know about your flight from Mississippi to Missouri

What is the cheapest month to book a flight from Mississippi to Missouri?

What is the cheapest time of day to fly from MS to MO?

Find hourly flight availability from Mississippi to Missouri. Discover flight options and departure times throughout the day, allowing you to choose a departure time that suits your schedule. Data last updated December 18, 2025.

How much does it cost to fly round-trip from Mississippi to Missouri?

Reviews of airlines servicing Missouri

Get a feel of what it's like to fly with Southwest, Delta, and American Airlines from Mississippi to Missouri by reading reviews from past customers. You can also see how each airline stacks up in terms of entertainment options, comfort, food, crew/service, and boarding process.

Related info for your journey

Find useful and relevant information for your journey from Mississippi to Missouri. Access travel guides, tips, and recommendations to enhance your travel experience. Get information about local attractions, weather, transportation options, and more.

How long is the flight from Mississippi to Missouri?

What are the cheapest airlines to fly from Mississippi to Missouri one-way?

Can I find deals for flights from Mississippi to Missouri that include hotel bookings?

How can I find direct flights from Mississippi to Missouri?

Can I find deals for business class flights from Mississippi to Missouri?

What is the cheapest month to book a flight from Mississippi to Missouri?

Browse thousands of different options on Cheapflights for your next trip

Toggle through the tabs below to find thousands of options on Cheapflights for your next trip.

Alternative routes for Mississippi to Missouri

See prices for flight routes from nearby airports that may be better suited for you.

Top 3 airlines flying from Mississippi to Missouri

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Cheapest flights from Mississippi to Missouri
Explore the most affordable flight options available from Mississippi to Missouri. Find the lowest fares from popular airlines and budget airlines, with prices last updated on December 18, 2025.