How popular is this Massachusetts to Missouri flight route?

The Massachusetts to Missouri flight path was viewed by 1 users in the past month. Keep an eye out for changes in search interest prior to high and low season.

How long is the flight from Massachusetts to Missouri?

Departing from Massachusetts to Missouri will take you 5h 09m. Massachusetts and Missouri are separated by a distance of 908 mi. This flight may include one or multiple stops.

In terms of precipitation, rainfall in Missouri ranges from 2.2 - 4.7 inches per month. May is typically the wettest month, when rainfall can reach 4.7 in. February is typically the driest time to visit Missouri when rainfall is around 2.2 in.

If weather is an important factor for your trip to Missouri, use this chart to help with planning. For those seeking warmer temperatures, July is the ideal time of year to visit, when temperatures reach an average of 80.6 F. Travelers looking to avoid the cold should look outside of January, when temperatures are typically at their lowest (around 32.0 F).

Can I find deals for flights from Massachusetts to Missouri that include hotel bookings?

Yes. In addition to deals on Massachusetts to Missouri flights, Cheapflights offers vacation packages that include both flights and hotel.

How can I find direct flights from Massachusetts to Missouri?

After entering your origin and destination, apply the non-stop filter on the search result page to find direct flights from Massachusetts to Missouri.

Can I find deals for business class flights from Massachusetts to Missouri?

Yes. Cheapflights offers flight deals from Massachusetts to Missouri by cabin class. In addition to browsing deals, you can also filter by cabin class on the search results page after making a search.

$63+ Flights from Massachusetts to Missouri

Home Search by date Vacation packages Hotels Flight deals Car rental Travel tips & news

Find cheap flights from Massachusetts to Missouri with Cheapflights

1. Tell us where you want to go

Enter your travel information like dates, passengers, trip type (one-way or round trip), and preferred cabin class then click “Find deals”

2. Select your favorite providers

We find the providers serving your travel needs. Choose up to four travel providers to compare side-by-side for flights, hotels, or car rentals.

3. Compare prices and book

Review each provider’s pricing and select the best option for you! Book through your favorite provider’s website for a seamless experience.

Cheap flight deals from Massachusetts to Missouri

Cheapest flights from Massachusetts to Missouri
Explore the most affordable flight options available from Massachusetts to Missouri. Find the lowest fares from popular airlines and budget airlines, with prices last updated on diciembre 16, 2025.

mié. 12/244:47 pmBDL - STL

1 stop7h 51mDelta

jue. 1/15:55 pmSTL - BDL

1 stop4h 19mDelta

Deal found 12/15

$269

dom. 12/215:45 amBOS - MCI

1 stop12h 25mSpirit Airlines

mié. 1/76:15 pmMCI - BOS

1 stop21h 13mSpirit Airlines

Deal found 12/14

$297

jue. 12/255:04 pmBDL - STL

1 stop5h 39mUnited Airlines

mié. 12/313:10 pmSTL - BDL

2 stops7h 48mUnited Airlines

Deal found 12/14

$309

jue. 12/1812:22 pmBOS - STL

1 stop11h 11mFrontier

mié. 12/314:27 pmSTL - BOS

1 stop16h 25mFrontier

Deal found 12/16

$329

mar. 12/3010:44 amBOS - COU

1 stop12h 15mAmerican Airlines

sáb. 1/33:19 pmCOU - BOS

1 stop8h 01mAmerican Airlines

Deal found 12/15

$335

jue. 12/251:48 pmBOS - STL

1 stop19h 47mAmerican Airlines

vie. 12/2610:01 amSTL - BOS

Nonstop2h 42mAmerican Airlines

Deal found 12/15

$345

mié. 12/316:07 amALB - STL

1 stop7h 14mDelta

dom. 1/45:59 pmSTL - ALB

1 stop4h 30mDelta

Deal found 12/16

$351

mié. 12/2411:09 amBOS - STL

1 stop23h 31mMultiple Airlines

dom. 1/115:11 pmSTL - BOS

2 stops22h 17mMultiple Airlines

Deal found 12/16

$357

mié. 12/2411:09 amBOS - STL

1 stop23h 31mFrontier

dom. 1/115:11 pmSTL - BOS

1 stop16h 35mFrontier

Deal found 12/16

$359

mar. 12/236:00 amBOS - STL

2 stops41h 33mMultiple Airlines

mar. 1/135:11 pmSTL - BOS

1 stop20h 27mMultiple Airlines

Deal found 12/16

$364

jue. 12/258:45 amBOS - STL

Nonstop3h 25mAmerican Airlines

jue. 1/15:00 amSTL - BOS

1 stop5h 06mAmerican Airlines

Deal found 12/15

$366

mié. 12/244:47 pmBDL - STL

1 stop7h 51mDelta

mar. 12/306:29 amSTL - BDL

1 stop4h 30mDelta

Deal found 12/14

$368

Best flights from Massachusetts to Missouri
Discover carefully curated flight deals from Massachusetts to Missouri that have cost, travel time, and layovers in mind to ensure you get the best travel experience. Data last updated diciembre 16, 2025.

dom. 1/185:30 amALB - STL

1 stop5h 09mDelta

mar. 1/206:35 amSTL - ALB

1 stop4h 14mDelta

Deal found 12/14

$235

dom. 1/185:45 amALB - STL

2 stops9h 45mUnited Airlines

mar. 1/208:05 amSTL - ALB

1 stop5h 26mUnited Airlines

Deal found 12/14

$240

mié. 1/147:00 amBOS - SGF

1 stop5h 49mAmerican Airlines

dom. 1/185:39 pmSGF - BOS

1 stop5h 12mAmerican Airlines

Deal found 12/15

$254

dom. 3/12:27 pmBDL - MCI

1 stop20h 33mMultiple Airlines

jue. 3/54:24 pmMCI - BDL

1 stop25h 49mMultiple Airlines

Deal found 12/15

$305

mar. 1/1312:10 pmBDL - MCI

1 stop6h 20mSouthwest

sáb. 1/176:20 amMCI - BDL

1 stop4h 35mSouthwest

Deal found 12/16

$307

mié. 2/254:36 pmBOS - MCI

1 stop24h 46mAlaska Airlines

lun. 3/25:16 pmMCI - BOS

2 stops29h 43mAlaska Airlines

Deal found 12/16

$428

jue. 1/159:30 amBOS - SGF

1 stop6h 08mUnited Airlines

dom. 1/187:45 amSGF - BOS

1 stop5h 44mUnited Airlines

Deal found 12/16

$257

dom. 1/116:15 amBDL - SGF

1 stop6h 59mAmerican Airlines

dom. 1/184:29 pmSGF - BDL

1 stop6h 04mAmerican Airlines

Deal found 12/15

$268

mié. 2/115:40 amALB - SGF

2 stops11h 35mDelta

lun. 2/165:11 pmSGF - ALB

1 stop5h 58mDelta

Deal found 12/15

$280

mié. 1/146:00 amBOS - SGF

2 stops9h 38mUnited Airlines

dom. 1/187:45 amSGF - BOS

2 stops8h 29mUnited Airlines

Deal found 12/15

$264

jue. 2/125:30 amBOS - SGF

1 stop7h 12mAmerican Airlines

mar. 2/176:10 pmSGF - BOS

1 stop4h 59mAmerican Airlines

Deal found 12/15

$270

lun. 3/22:25 pmALB - STL

2 stops9h 10mSouthwest

mié. 3/46:50 amSTL - ALB

1 stop4h 30mSouthwest

Deal found 12/13

$307

lun. 1/59:41 pmALB - MCI

2 stops20h 29mMultiple Airlines

jue. 1/811:26 amMCI - ALB

2 stops20h 21mMultiple Airlines

Deal found 12/14

$310

jue. 2/59:30 amBOS - SGF

1 stop6h 08mUnited Airlines

mié. 2/117:45 amSGF - BOS

1 stop5h 45mUnited Airlines

Deal found 12/15

$270

mar. 1/133:30 pmBOS - SGF

1 stop7h 16mDelta

lun. 1/195:00 pmSGF - BOS

1 stop7h 04mDelta

Deal found 12/15

$308

vie. 2/209:58 amALB - MCI

1 stop10h 02mMultiple Airlines

lun. 2/2310:55 amMCI - ALB

2 stops23h 38mMultiple Airlines

Deal found 12/13

$311

vie. 1/1612:55 pmBOS - SGF

1 stop8h 30mAmerican Airlines

jue. 1/228:18 amSGF - BOS

1 stop6h 37mAmerican Airlines

Deal found 12/15

$289

sáb. 1/175:50 amALB - MCI

1 stop5h 00mSouthwest

lun. 1/1912:55 pmMCI - ALB

1 stop8h 10mSouthwest

Deal found 12/13

$327

sáb. 1/179:50 amALB - SGF

2 stops11h 46mUnited Airlines

mar. 1/273:14 pmSGF - ALB

1 stop5h 09mUnited Airlines

Deal found 12/16

$274

mar. 6/94:20 pmBOS - SGF

1 stop7h 15mDelta

dom. 6/143:35 pmSGF - BOS

1 stop8h 28mDelta

Deal found 12/15

$314

mar. 1/69:05 amBDL - MCI

2 stops33h 05mMultiple Airlines

lun. 1/1212:50 pmMCI - BDL

1 stop30h 15mMultiple Airlines

Deal found 12/15

$322

mié. 2/117:02 amALB - SGF

1 stop5h 47mAmerican Airlines

lun. 2/1610:23 amSGF - ALB

1 stop5h 10mAmerican Airlines

Deal found 12/15

$305

dom. 1/117:50 amBDL - SGF

1 stop9h 32mUnited Airlines

dom. 1/181:28 pmSGF - BDL

2 stops9h 16mUnited Airlines

Deal found 12/15

$287

mar. 2/175:15 amBDL - STL

1 stop5h 20mSouthwest

dom. 2/222:05 pmSTL - BDL

1 stop9h 05mSouthwest

Deal found 12/16

$349

sáb. 1/172:30 pmALB - MCI

1 stop6h 32mDelta

lun. 1/195:50 amMCI - ALB

1 stop5h 05mDelta

Deal found 12/14

$327

vie. 2/67:00 amBOS - COU

1 stop8h 48mAmerican Airlines

dom. 2/86:00 amCOU - BOS

1 stop9h 43mAmerican Airlines

Deal found 12/15

$305

vie. 1/91:30 pmBOS - SGF

2 stops9h 28mUnited Airlines

lun. 1/123:14 pmSGF - BOS

1 stop5h 24mUnited Airlines

Deal found 12/16

$294

lun. 2/235:35 amALB - STL

1 stop7h 48mDelta

lun. 3/25:50 pmSTL - ALB

1 stop4h 34mDelta

Deal found 12/14

$327

jue. 1/293:30 pmBDL - STL

2 stops7h 25mSouthwest

sáb. 1/315:10 amSTL - BDL

2 stops9h 45mSouthwest

Deal found 12/15

$362

jue. 1/157:00 amBOS - COU

1 stop15h 10mAmerican Airlines

jue. 1/226:00 amCOU - BOS

1 stop8h 17mAmerican Airlines

Deal found 12/16

$305

Last-minute flights from Massachusetts to Missouri
Discover last-minute flight deals from Massachusetts to Missouri. Data last updated diciembre 16, 2025 and is based on user searches.

mié. 1/75:03 pmBDL - STL

2 stops22h 45mFrontier

mié. 1/148:32 pmSTL - BDL

1 stop13h 19mFrontier

Deal found 12/15

$217

mié. 1/78:05 amBDL - STL

1 stop15h 28mMultiple Airlines

mié. 1/148:32 pmSTL - BDL

1 stop13h 19mMultiple Airlines

Deal found 12/15

$225

jue. 1/87:10 amBDL - STL

2 stops25h 40mMultiple Airlines

dom. 1/115:11 pmSTL - BDL

1 stop25h 13mMultiple Airlines

Deal found 12/15

$191

vie. 1/97:00 amBOS - MCI

1 stop10h 09mSpirit Airlines

lun. 1/1211:26 amMCI - BOS

1 stop11h 31mSpirit Airlines

Deal found 12/16

$228

vie. 1/91:56 pmBDL - STL

2 stops9h 37mMultiple Airlines

dom. 1/115:11 pmSTL - BDL

1 stop25h 13mMultiple Airlines

Deal found 12/15

$244

sáb. 1/1012:38 pmBDL - STL

1 stop10h 55mFrontier

vie. 3/67:52 amSTL - BDL

1 stop10h 21mFrontier

Deal found 12/16

$229

dom. 1/116:00 amBOS - MCI

1 stop29h 09mMultiple Airlines

mié. 1/145:04 pmMCI - BOS

1 stop17h 06mMultiple Airlines

Deal found 12/15

$229

mar. 1/138:05 amBDL - STL

2 stops15h 29mMultiple Airlines

mar. 1/205:42 pmSTL - BDL

1 stop20h 23mMultiple Airlines

Deal found 12/16

$241

dom. 1/185:30 amALB - STL

1 stop5h 09mDelta

mar. 1/206:35 amSTL - ALB

1 stop4h 14mDelta

Deal found 12/14

$235

dom. 1/185:45 amALB - STL

2 stops9h 45mUnited Airlines

mar. 1/208:05 amSTL - ALB

1 stop5h 26mUnited Airlines

Deal found 12/14

$240

jue. 1/298:31 pmBDL - STL

1 stop14h 52mFrontier

sáb. 1/318:22 pmSTL - BDL

1 stop13h 54mFrontier

Deal found 12/15

$189

vie. 1/307:13 pmBDL - STL

2 stops16h 58mMultiple Airlines

vie. 2/65:42 pmSTL - BDL

1 stop24h 24mMultiple Airlines

Deal found 12/15

$199

One-way flights from Massachusetts to Missouri
Search for one-way flight options from Massachusetts to Missouri. Find affordable one-way fares based on user searches. Data last updated diciembre 16, 2025.

mar. 2/176:00 amBOS - STL

1 stop25h 51mFrontier

Deal found 12/15

$63

jue. 1/157:00 amBOS - STL

1 stop16h 34mMultiple Airlines

Deal found 12/15

$64

jue. 1/1512:10 pmBOS - STL

1 stop11h 24mFrontier

Deal found 12/16

$65

mié. 1/712:29 pmBOS - STL

1 stop11h 04mMultiple Airlines

Deal found 12/15

$67

mié. 1/75:45 amBOS - MCI

1 stop12h 25mSpirit Airlines

Deal found 12/15

$67

mar. 1/136:00 amBOS - STL

1 stop25h 51mFrontier

Deal found 12/16

$68

mié. 2/252:23 pmBOS - STL

1 stop9h 04mMultiple Airlines

Deal found 12/16

$76

jue. 1/85:27 pmBOS - MCI

1 stop18h 04mSpirit Airlines

Deal found 12/14

$78

dom. 1/258:31 pmBDL - STL

1 stop13h 50mFrontier

Deal found 12/16

$79

mar. 2/37:00 amBOS - MCI

1 stop10h 09mSpirit Airlines

Deal found 12/15

$79

sáb. 1/1712:10 pmBOS - STL

1 stop11h 24mFrontier

Deal found 12/16

$80

sáb. 2/287:00 amBOS - MCI

1 stop9h 29mSpirit Airlines

Deal found 12/15

$84

Find flight deals from Massachusetts to Missouri

Most accurate provider	eDreams 3 stars
Most trusted provider	eDreams 3 stars
Round-trip from	$189 (Kiwi.com)
One-way from	$63 (Trip.com)
Popular in	April
Cheapest in	August
Average price	$461
Good round-trip deal	$371 or less
Good one-way deal	$193 or less

Provider with most accurate pricing for Boston Logan Intl-Lambert-St Louis flight deals.

Search Deals

Provider most trusted by Cheapflights users for Boston Logan Intl-Lambert-St Louis flights.

Search Deals

From Massachusetts to Missouri

Search Deals

One-way flight from Massachusetts to Missouri

Search Deals

Highest demand for flights based on searches. 7% potential increase in price ($38 potential increase over avg. RT price).

Search Deals

Cheapest flight prices on average. 1% potential price decrease ($7 potential savings vs. average RT price).

Search Deals

Average for round-trip flights in December 2025

Search Deals

Price to beat on a round-trip flight from Massachusetts to Missouri.

Search Deals

Price to beat on a one-way flight from Massachusetts to Missouri.

Search Deals

Cheapflights Fare Finder

Use the filters below to find and compare flights from Massachusetts to Missouri that are best for you.

Fly from

Fly to

Route

Depart

Return

Price

AlbanySt. Louis

ALB - STL

ALBSTL

Albany Intl

dom. 1/18

5:30 am-9:39 am

1 stop5h 09m

Lambert-St Louis

mar. 1/20

6:35 am-11:49 am

1 stop4h 14m

$235

AlbanySt. Louis

ALB - STL

ALBSTL

Albany Intl

dom. 1/18

5:45 am-2:30 pm

2 stops9h 45m

Lambert-St Louis

mar. 1/20

8:05 am-2:31 pm

1 stop5h 26m

$240

BostonSpringfield

BOS - SGF

BOSSGF

Boston Logan Intl

mié. 1/14

7:00 am-11:49 am

1 stop5h 49m

Springfield-Branson

dom. 1/18

5:39 pm-11:51 pm

1 stop5h 12m

$254

BostonSpringfield

BOS - SGF

BOSSGF

Boston Logan Intl

jue. 1/15

9:30 am-2:38 pm

1 stop6h 08m

Springfield-Branson

dom. 1/18

7:45 am-2:29 pm

1 stop5h 44m

$257

BostonSpringfield

BOS - SGF

BOSSGF

Boston Logan Intl

mié. 1/14

6:00 am-2:38 pm

2 stops9h 38m

Springfield-Branson

dom. 1/18

7:45 am-5:14 pm

2 stops8h 29m

$264

HartfordSpringfield

BDL - SGF

BDLSGF

Hartford Bradley Intl

dom. 1/11

6:15 am-12:14 pm

1 stop6h 59m

Springfield-Branson

dom. 1/18

4:29 pm-11:33 pm

1 stop6h 04m

$268

BostonSpringfield

BOS - SGF

BOSSGF

Boston Logan Intl

jue. 2/12

5:30 am-11:42 am

1 stop7h 12m

Springfield-Branson

mar. 2/17

6:10 pm-12:09 am

1 stop4h 59m

$270

BostonSpringfield

BOS - SGF

BOSSGF

Boston Logan Intl

jue. 2/5

9:30 am-2:38 pm

1 stop6h 08m

Springfield-Branson

mié. 2/11

7:45 am-2:30 pm

1 stop5h 45m

$270

AlbanySpringfield

ALB - SGF

ALBSGF

Albany Intl

sáb. 1/17

9:50 am-8:36 pm

2 stops11h 46m

Springfield-Branson

mar. 1/27

3:14 pm-9:23 pm

1 stop5h 09m

$274

AlbanySpringfield

ALB - SGF

ALBSGF

Albany Intl

mié. 2/11

5:40 am-4:15 pm

2 stops11h 35m

Springfield-Branson

lun. 2/16

5:11 pm-12:09 am

1 stop5h 58m

$280

Flights are sorted by cheapest round-trip flights first.

Deals found on 12/15

Showing 1-10 of 60 results

...

Best time to book a flight from Massachusetts to Missouri

Have a flexible travel schedule? Discover the best time to fly to Missouri from Massachusetts with our price prediction graph.

Estimated round-trip price

Rates are based on past data. Find the cheapest month and day to book your flight based on your travel requirements, then search for cheap deals.

Cheapflights Insights

Everything you need to know about your flight from Massachusetts to Missouri

What is the cheapest month to book a flight from Massachusetts to Missouri?

Currently, December is the cheapest month in which you can book a flight from Massachusetts to Missouri (average of $107). Flying from Massachusetts to Missouri in March is currently the most expensive (average of $292). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.

What is the cheapest time of day to fly from MA to MO?

Unlike in the evening, when flights are generally more expensive, you can save up to 25% on flights from Massachusetts to Missouri by exploring options for tickets at noon.

What is the cheapest day to fly from Massachusetts to Missouri?

Travelers seeking maximum savings on their Massachusetts to Missouri flight should consider departing on Saturday mornings when fares are most often at their lowest. Sunday evenings flights should be avoided if possible as fares are typically the most expensive at this time.

Reviews of airlines servicing Missouri

Peruse reviews from past customers who have flown with Southwest, Delta, and United Airlines from Massachusetts to Missouri to help guide your decision. Users can see the overall rating for each airline as well as how each is rated in terms of entertainment options, comfort, food, crew/service, and boarding process.

Southwest

7.9

Good

4,250 reviews

Reviews

1 / 20

2.0

Mediocre

Thomas,Dec 2025

SEA - DEN

Plane two hours late in leaving 1:00 pm west coat time got home next day at 2:45am most car rental places are closed and don’t open till 5am

Southwest

7.9

Good

4,250 reviews

Southwest

7.9

Good

4,250 reviews

Reviews

1 / 20

2.0

Mediocre

Thomas,Dec 2025

SEA - DEN

Plane two hours late in leaving 1:00 pm west coat time got home next day at 2:45am most car rental places are closed and don’t open till 5am

Delta

7.9

Good

8,008 reviews

Southwest

7.9

Good

4,250 reviews

Reviews

1 / 20

2.0

Mediocre

Thomas,Dec 2025

SEA - DEN

Plane two hours late in leaving 1:00 pm west coat time got home next day at 2:45am most car rental places are closed and don’t open till 5am

United Airlines

7.4

Good

9,092 reviews

Southwest

7.9

Good

4,250 reviews

Reviews

1 / 20

2.0

Mediocre

Thomas,Dec 2025

SEA - DEN

Plane two hours late in leaving 1:00 pm west coat time got home next day at 2:45am most car rental places are closed and don’t open till 5am

American Airlines

7.2

Good

11,049 reviews

Southwest

7.9

Good

4,250 reviews

Reviews

1 / 20

2.0

Mediocre

Thomas,Dec 2025

SEA - DEN

Plane two hours late in leaving 1:00 pm west coat time got home next day at 2:45am most car rental places are closed and don’t open till 5am

Spirit Airlines

6.3

Okay

8,186 reviews

Southwest

7.9

Good

4,250 reviews

Reviews

1 / 20

2.0

Mediocre

Thomas,Dec 2025

SEA - DEN

Plane two hours late in leaving 1:00 pm west coat time got home next day at 2:45am most car rental places are closed and don’t open till 5am

Related info for your journey

How popular is this Massachusetts to Missouri flight route?
The Massachusetts to Missouri flight path was viewed by 1 users in the past month. Keep an eye out for changes in search interest prior to high and low season.
How long is the flight from Massachusetts to Missouri?
Departing from Massachusetts to Missouri will take you 5h 09m. Massachusetts and Missouri are separated by a distance of 908 mi. This flight may include one or multiple stops.
Can I find deals for flights from Massachusetts to Missouri that include hotel bookings?
Yes. In addition to deals on Massachusetts to Missouri flights, Cheapflights offers vacation packages that include both flights and hotel.
How can I find direct flights from Massachusetts to Missouri?
After entering your origin and destination, apply the non-stop filter on the search result page to find direct flights from Massachusetts to Missouri.
Can I find deals for business class flights from Massachusetts to Missouri?
Yes. Cheapflights offers flight deals from Massachusetts to Missouri by cabin class. In addition to browsing deals, you can also filter by cabin class on the search results page after making a search.
What is the cheapest month to book a flight from Massachusetts to Missouri?
Currently, December is the cheapest month in which you can book a flight from Massachusetts to Missouri (average of $107). Flying from Massachusetts to Missouri in March is currently the most expensive (average of $292). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.

See more FAQs

Browse thousands of different options on Cheapflights for your next trip

Top 6 airlines flying from Massachusetts to Missouri

Airline	Cheapest	Average	Flexibility	On-time
Spirit Airlines	Cheapest$71	Average$282	FlexibilityNo cancel fee	On-time65%
Frontier	Cheapest$90	Average$289	FlexibilityNo cancel fee	On-time62%
American Airlines	Cheapest$208	Average$495	FlexibilityNo cancel fee	On-time71%
Delta	Cheapest$216	Average$416	FlexibilityNo cancel fee	On-timeN/A
United Airlines	Cheapest$281	Average$492	FlexibilityNo cancel fee	On-time69%
Southwest	Cheapest$313	Average$446	FlexibilityNo cancel fee	On-time63%

100% Free

Cheapflights is completely free to use, so you can start saving the moment you arrive.

Book with Flexibility

Our users can plan ahead with confidence and find flights with no change fees

Travel Smart

Millions of people come to us for their flight needs every year. We help make travel planning easy by providing useful insights and data-driven graphs that can inform your decisions.

$63+ Cheap flights from Massachusetts to Missouri

This is the cheapest one-way flight price found by a Cheapflights user in the last 72 hours by searching for a flight departing on 2/17. Fares are subject to change and may not be available on all flights or dates of travel.

Find cheap flights from Massachusetts to Missouri with Cheapflights

1. Tell us where you want to go

2. Select your favorite providers

3. Compare prices and book

Cheap flight deals from Massachusetts to Missouri

Cheapest flights from Massachusetts to MissouriExplore the most affordable flight options available from Massachusetts to Missouri. Find the lowest fares from popular airlines and budget airlines, with prices last updated on diciembre 16, 2025.

Explore the most affordable flight options available from Massachusetts to Missouri. Find the lowest fares from popular airlines and budget airlines, with prices last updated on diciembre 16, 2025.

Find flight deals from Massachusetts to Missouri

Keep the following information in mind while searching for Massachusetts to Missouri flight deals. Data was last updated diciembre 16, 2025.

Most accurate provider

Most trusted provider

Round-trip from

One-way from

Popular in

Cheapest in

Average price

Good round-trip deal

Good one-way deal

Cheapflights Fare Finder

Use the filters below to find and compare flights from Massachusetts to Missouri that are best for you.

Best time to book a flight from Massachusetts to Missouri

Have a flexible travel schedule? Discover the best time to fly to Missouri from Massachusetts with our price prediction graph.

Cheapflights Insights

Everything you need to know about your flight from Massachusetts to Missouri

What is the cheapest month to book a flight from Massachusetts to Missouri?

What is the cheapest time of day to fly from MA to MO?

Find hourly flight availability from Massachusetts to Missouri. Discover flight options and departure times throughout the day, allowing you to choose a departure time that suits your schedule. Data last updated diciembre 16, 2025.

What is the cheapest day to fly from Massachusetts to Missouri?

Use this chart to determine the cheapest time to fly round-trip from Massachusetts to Missouri. Price data was last updated on December 16, 2024.

Reviews of airlines servicing Missouri

Related info for your journey

Find useful and relevant information for your journey from Massachusetts to Missouri. Access travel guides, tips, and recommendations to enhance your travel experience. Get information about local attractions, weather, transportation options, and more.

How popular is this Massachusetts to Missouri flight route?

How long is the flight from Massachusetts to Missouri?

Can I find deals for flights from Massachusetts to Missouri that include hotel bookings?

How can I find direct flights from Massachusetts to Missouri?

Can I find deals for business class flights from Massachusetts to Missouri?

What is the cheapest month to book a flight from Massachusetts to Missouri?

Browse thousands of different options on Cheapflights for your next trip

Toggle through the tabs below to find thousands of options on Cheapflights for your next trip.

Alternative routes for Massachusetts to Missouri

See prices for flight routes from nearby airports that may be better suited for you.

Top 6 airlines flying from Massachusetts to Missouri

100% Free

Book with Flexibility

Travel Smart

Cheapest flights from Massachusetts to Missouri
Explore the most affordable flight options available from Massachusetts to Missouri. Find the lowest fares from popular airlines and budget airlines, with prices last updated on diciembre 16, 2025.