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$150+ Cheap flights from LaGuardia, NY (LGA) to Missouri

This is the cheapest one-way flight price found by a Cheapflights user in the last 72 hours by searching for a flight departing on 4/22. Fares are subject to change and may not be available on all flights or dates of travel.
LGA — STL
May 18 — May 251
Mon 5/18
Mon 5/25
1 adult, Economy
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Cheap flight deals from LaGuardia to Missouri

Cheapest flights from LaGuardia to Missouri
Explore the most affordable flight options available from LaGuardia to Missouri. Find the lowest fares from popular airlines and budget airlines, with prices last updated on April 18, 2026.

This Delta deal was found by Cheapflights users on 4/17. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 8/186:00 pm
LGA
-
SGF
1 stop5h 29m
Delta
Tue 8/253:30 pm
SGF
-
LGA
1 stop5h 23m
Delta
Deal found 4/17$283
This Kiwi.com deal was found by Cheapflights users on 4/12. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 5/1410:00 pm
LGA
-
STL
1 stop11h 55m
Frontier
Sun 5/176:55 pm
STL
-
LGA
2 stops26h 05m
Frontier
Deal found 4/12$295
This Southwest deal was found by Cheapflights users on 4/15. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 5/63:05 pm
LGA
-
STL
Nonstop2h 55m
Southwest
Wed 7/87:55 pm
STL
-
LGA
Nonstop2h 25m
Southwest
Deal found 4/15$296
This Kiwi.com deal was found by Cheapflights users on 4/14. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 4/293:29 pm
LGA
-
STL
1 stop8h 50m
Multiple Airlines
Tue 5/126:33 pm
STL
-
LGA
1 stop22h 15m
Multiple Airlines
Deal found 4/14$297
This Kiwi.com deal was found by Cheapflights users on 4/14. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 5/1710:00 pm
LGA
-
STL
1 stop11h 55m
Multiple Airlines
Mon 5/185:27 pm
STL
-
LGA
2 stops15h 33m
Multiple Airlines
Deal found 4/14$298
This Kiwi.com deal was found by Cheapflights users on 4/13. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 6/1610:00 pm
LGA
-
STL
1 stop11h 52m
Multiple Airlines
Thu 6/188:08 pm
STL
-
LGA
2 stops17h 20m
Multiple Airlines
Deal found 4/13$299
This Southwest deal was found by Cheapflights users on 4/13. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 6/88:55 am
LGA
-
STL
Nonstop2h 50m
Southwest
Tue 6/95:55 pm
STL
-
LGA
1 stop4h 00m
Southwest
Deal found 4/13$300
This Gotogate deal was found by Cheapflights users on 4/14. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Gotogate is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 4/236:00 am
LGA
-
STL
1 stop5h 30m
Frontier
Thu 4/234:59 pm
STL
-
LGA
1 stop22h 05m
Frontier
Deal found 4/14$301
This CheapOair deal was found by Cheapflights users on 4/16. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure CheapOair is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 4/228:25 pm
LGA
-
STL
1 stop27h 54m
Frontier
Fri 4/248:39 am
STL
-
LGA
1 stop12h 25m
Frontier
Deal found 4/16$302
This Delta deal was found by Cheapflights users on 4/13. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 6/21:55 pm
LGA
-
STL
Nonstop2h 45m
Delta
Tue 6/96:10 pm
STL
-
LGA
1 stop4h 31m
Delta
Deal found 4/13$303
This American Airlines deal was found by Cheapflights users on 4/15. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 7/75:25 pm
LGA
-
SGF
1 stop6h 15m
American Airlines
Wed 7/156:53 am
SGF
-
LGA
1 stop7h 12m
American Airlines
Deal found 4/15$303
This Southwest deal was found by Cheapflights users on 4/14. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 5/237:35 am
LGA
-
STL
1 stop7h 25m
Southwest
Wed 5/2711:05 am
STL
-
LGA
Nonstop2h 20m
Southwest
Deal found 4/14$304

Find flight deals from LaGuardia to Missouri

Keep the following information in mind while searching for LaGuardia to Missouri flight deals. Data was last updated April 18, 2026.

Most accurate provider

FlightHub
3 stars

Most trusted provider

FlightHub
3 stars

Round-trip from

$283
(Delta)

One-way from

$150
(Kiwi.com)

Popular in

November

Cheapest in

August

Average price

$369

Good round-trip deal

$345 or less

Good one-way deal

$183 or less
Provider with most accurate pricing for New York (NYC)-Lambert-St Louis flight deals.
Search Deals
Provider most trusted by Cheapflights users for New York (NYC)-Lambert-St Louis flights.
Search Deals
From New York LaGuardia to Missouri
Search Deals
One-way flight from New York LaGuardia to Missouri
Search Deals
Highest demand for flights based on searches. 7% potential increase in price ($31 potential increase over avg. RT price).
Search Deals
Cheapest flight prices on average. 1% potential price decrease ($5 potential savings vs. average RT price).
Search Deals
Average for round-trip flights in April 2026
Search Deals
Price to beat on a round-trip flight from New York LaGuardia to Missouri.
Search Deals
Price to beat on a one-way flight from New York LaGuardia to Missouri.
Search Deals

Cheapflights Fare Finder

 
Customize your flight search to find flights from LaGuardia to Missouri that fit within your specific budget. Explore options based on user searches and filter the results based on your desired price range. Find flights that match your budget for a cost-effective journey. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated April 18, 2026.
Use the filters below to find and compare flights from New York LaGuardia Airport to Missouri that are best for you.

Fly from

Fly to

Route

Depart

Return

Price

Cheapest round-trip

New YorkSpringfield

LGA - SGF

LGASGF

New York LaGuardia

Tue 8/18

10:00 am-2:45 pm

1 stop5h 45m

Springfield-Branson

Wed 8/26

3:30 pm-11:50 pm

1 stop7h 20m

$283

New YorkSt. Louis

LGA - STL

LGASTL

New York LaGuardia

Sat 5/23

3:35 pm-7:45 pm

1 stop5h 10m

Lambert-St Louis

Tue 5/26

7:35 pm-11:00 pm

Nonstop2h 25m

$304
Quickest round-trip

New YorkSt. Louis

LGA - STL

LGASTL

New York LaGuardia

Sat 5/30

6:00 am-7:45 am

Nonstop2h 45m

Lambert-St Louis

Sat 6/6

8:00 pm-11:25 pm

Nonstop2h 25m

$315

New YorkSt. Louis

LGA - STL

LGASTL

New York LaGuardia

Thu 5/7

1:55 pm-3:40 pm

Nonstop2h 45m

Lambert-St Louis

Mon 5/11

5:45 pm-9:14 pm

Nonstop2h 29m

$315

New YorkSt. Louis

LGA - STL

LGASTL

New York LaGuardia

Wed 5/6

7:15 pm-9:09 pm

Nonstop2h 54m

Lambert-St Louis

Wed 7/8

9:24 am-12:55 pm

Nonstop2h 31m

$316

New YorkSt. Louis

LGA - STL

LGASTL

New York LaGuardia

Sat 5/23

4:00 pm-9:38 pm

1 stop6h 38m

Lambert-St Louis

Sun 5/24

6:00 am-9:28 am

Nonstop2h 28m

$327

New YorkSt. Louis

LGA - STL

LGASTL

New York LaGuardia

Wed 6/24

6:05 am-12:05 pm

1 stop7h 00m

Lambert-St Louis

Thu 6/25

5:40 am-9:00 am

Nonstop2h 20m

$331

New YorkSpringfield

LGA - SGF

LGASGF

New York LaGuardia

Mon 8/17

3:00 pm-10:29 pm

1 stop8h 29m

Springfield-Branson

Tue 8/25

3:30 pm-10:50 pm

1 stop6h 20m

$331

New YorkSt. Louis

LGA - STL

LGASTL

New York LaGuardia

Sun 5/17

6:30 am-8:13 am

Nonstop2h 43m

Lambert-St Louis

Sun 5/24

6:00 am-9:28 am

Nonstop2h 28m

$344

New YorkKansas City

LGA - MCI

LGAMCI

New York LaGuardia

Sat 5/9

5:00 pm-7:24 pm

Nonstop3h 24m

Kansas City

Mon 5/11

10:45 am-2:38 pm

Nonstop2h 53m

$345

Flights are sorted by cheapest round-trip flights first.

Deals found on 4/13

Showing 1-10 of 60 resultsSorted by cheapest first
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Best time to book a flight from LaGuardia to Missouri

Have a flexible travel schedule? Discover the best time to fly to Missouri from LaGuardia with our price prediction graph.
Estimated round-trip price
Rates are based on past data. Find the cheapest month and day to book your flight based on your travel requirements, then search for cheap deals.

Cheapflights Insights

Everything you need to know about your flight from New York LaGuardia Airport to Missouri

What is the cheapest month to book a flight from New York LaGuardia Airport to Missouri?

Currently, July is the cheapest month in which you can book a flight from New York LaGuardia Airport to Missouri (average of $129). Flying from New York LaGuardia Airport to Missouri in March is currently the most expensive (average of $259). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.

What is the cheapest time of day to fly from LGA to MO?

Find hourly flight availability from LaGuardia to Missouri. Discover flight options and departure times throughout the day, allowing you to choose a departure time that suits your schedule. Data last updated April 18, 2026.

Unlike in the afternoon, when flights are generally more expensive, you can save up to 1% on flights from New York LaGuardia Airport to Missouri by exploring options for tickets in the evening.

What is the cheapest day to fly from New York LaGuardia Airport to Missouri?

Use this chart to determine the cheapest time to fly round-trip from LaGuardia to Missouri. Price data was last updated on April 11, 2026.

Travelers seeking maximum savings on their New York LaGuardia Airport to Missouri flight should consider departing on Saturday evenings when fares are most often at their lowest. Sunday at noon flights should be avoided if possible as fares are typically the most expensive at this time.

Weekly flight availability from New York LaGuardia Airport to Missouri

Explore weekly flight availability from LaGuardia to Missouri. Discover flights operating on different days of the week, giving you the flexibility to choose a travel day that best fits your plans. Compare info to find the most convenient option for your journey. Data last updated April 18, 2026.

The most flights from LGA to USMO are scheduled on a Monday (14 on average). You will have fewer flight options on Saturday, which is when the least amount of flights are scheduled (1 on average).

How much does it cost to fly round-trip from New York LaGuardia Airport to Missouri?

Reviews of airlines servicing Missouri

Get insights into the airlines that provide service to Missouri. Read reviews, discover amenities, and learn about the overall travel experience offered by airlines. Use this information to make informed decisions when choosing an airline for your flight to Missouri. Reviews last updated April 18, 2026.
See what other customers who have flown with Southwest,Delta, andUnited Airlines from New York LaGuardia Airport to Missouri have to say. Users can see the overall rating for each airline as well as how each is rated in terms of entertainment options, comfort, food, crew/service, and boarding process.
Southwest
8.0
Very good
4,330 reviews

Overall

8.0

Crew

8.6

Food

7.0

Boarding

8.1

Comfort

8.0

Entertainment

7.5

Reviews

1 / 20
2.0
Mediocre

Dominic,Mar 2026

MCO - SMF

I had to try and sleep on the floor of the Austin airport. I spent 12 hours there. The airline policies were so poor, that a near violent argument broke out between the people in front of me and the flight attendants - making for a super stressful situation at 30,000 feet. Garbage airline choice by Kayak Garbage idea to book a flight with a layover. Next time I will pay for a quality booking myself, and somehow force the company to reimburse it.
Southwest
8.0
Very good
4,330 reviews
Southwest
8.0
Very good
4,330 reviews

Overall

8.0

Crew

8.6

Food

7.0

Boarding

8.1

Comfort

8.0

Entertainment

7.5

Reviews

1 / 20
2.0
Mediocre

Dominic,Mar 2026

MCO - SMF

I had to try and sleep on the floor of the Austin airport. I spent 12 hours there. The airline policies were so poor, that a near violent argument broke out between the people in front of me and the flight attendants - making for a super stressful situation at 30,000 feet. Garbage airline choice by Kayak Garbage idea to book a flight with a layover. Next time I will pay for a quality booking myself, and somehow force the company to reimburse it.
Delta
7.9
Good
8,424 reviews
Southwest
8.0
Very good
4,330 reviews

Overall

8.0

Crew

8.6

Food

7.0

Boarding

8.1

Comfort

8.0

Entertainment

7.5

Reviews

1 / 20
2.0
Mediocre

Dominic,Mar 2026

MCO - SMF

I had to try and sleep on the floor of the Austin airport. I spent 12 hours there. The airline policies were so poor, that a near violent argument broke out between the people in front of me and the flight attendants - making for a super stressful situation at 30,000 feet. Garbage airline choice by Kayak Garbage idea to book a flight with a layover. Next time I will pay for a quality booking myself, and somehow force the company to reimburse it.
United Airlines
7.4
Good
9,605 reviews
Southwest
8.0
Very good
4,330 reviews

Overall

8.0

Crew

8.6

Food

7.0

Boarding

8.1

Comfort

8.0

Entertainment

7.5

Reviews

1 / 20
2.0
Mediocre

Dominic,Mar 2026

MCO - SMF

I had to try and sleep on the floor of the Austin airport. I spent 12 hours there. The airline policies were so poor, that a near violent argument broke out between the people in front of me and the flight attendants - making for a super stressful situation at 30,000 feet. Garbage airline choice by Kayak Garbage idea to book a flight with a layover. Next time I will pay for a quality booking myself, and somehow force the company to reimburse it.
American Airlines
7.1
Good
11,604 reviews
Southwest
8.0
Very good
4,330 reviews

Overall

8.0

Crew

8.6

Food

7.0

Boarding

8.1

Comfort

8.0

Entertainment

7.5

Reviews

1 / 20
2.0
Mediocre

Dominic,Mar 2026

MCO - SMF

I had to try and sleep on the floor of the Austin airport. I spent 12 hours there. The airline policies were so poor, that a near violent argument broke out between the people in front of me and the flight attendants - making for a super stressful situation at 30,000 feet. Garbage airline choice by Kayak Garbage idea to book a flight with a layover. Next time I will pay for a quality booking myself, and somehow force the company to reimburse it.
Frontier
5.7
Fair
2,987 reviews
Southwest
8.0
Very good
4,330 reviews

Overall

8.0

Crew

8.6

Food

7.0

Boarding

8.1

Comfort

8.0

Entertainment

7.5

Reviews

1 / 20
2.0
Mediocre

Dominic,Mar 2026

MCO - SMF

I had to try and sleep on the floor of the Austin airport. I spent 12 hours there. The airline policies were so poor, that a near violent argument broke out between the people in front of me and the flight attendants - making for a super stressful situation at 30,000 feet. Garbage airline choice by Kayak Garbage idea to book a flight with a layover. Next time I will pay for a quality booking myself, and somehow force the company to reimburse it.

Related info for your journey

Find useful and relevant information for your journey from LaGuardia to Missouri. Access travel guides, tips, and recommendations to enhance your travel experience. Get information about local attractions, weather, transportation options, and more.

  • How long is the flight from New York LaGuardia Airport to Missouri?

    Departing from New York LaGuardia Airport to Missouri will take you 5h 10m. New York LaGuardia Airport and Missouri are separated by a distance of 885 mi. Both multi-stop and nonstop flights can be found to your destination and back.

  • What are the cheapest airlines to fly from New York LaGuardia Airport to Missouri one-way?

    The cheapest airline one-way is Spirit Airlines, with whom users have recently found tickets for as low as $61. However, be on the lookout for offers from United Airlines and Delta, as they are both options that can get you from New York LaGuardia Airport to Missouri for a low price.

  • What are the most popular routes from New York LaGuardia Airport to Missouri?

    When deciding which route to take from New York LaGuardia Airport to Missouri consider New York LaGuardia - Lambert-St Louis, New York LaGuardia - Kansas City or New York LaGuardia - Springfield-Branson as they are the most popular.

  • What are the most reliable airlines from New York LaGuardia Airport to Missouri?

    Looking for the most reliable airlines to get you to your destination on time? Our data shows these are most likely to get you from New York LaGuardia Airport to Missouri on time: Republic Airways (78%), American Airlines (77%), Delta (76%).

  • What are the cheapest flights from New York LaGuardia Airport to Missouri?

    The cheapest flight price from New York LaGuardia Airport to Missouri is $129. On average you can expect to pay $441. The most popular route, (New York LaGuardia - Lambert-St Louis), can usually be booked for $187.

  • Can I find deals for flights from LaGuardia to Missouri that include hotel bookings?

    Yes. In addition to deals on LaGuardia to Missouri flights, Cheapflights offers vacation packages that include both flights and hotel.

  • How can I find direct flights from LaGuardia to Missouri?

    After entering your origin and destination, apply the non-stop filter on the search result page to find direct flights from LaGuardia to Missouri.

  • Can I find deals for business class flights from LaGuardia to Missouri?

    Yes. Cheapflights offers flight deals from LaGuardia to Missouri by cabin class. In addition to browsing deals, you can also filter by cabin class on the search results page after making a search.

  • What is the cheapest month to book a flight from New York LaGuardia Airport to Missouri?

    Currently, July is the cheapest month in which you can book a flight from New York LaGuardia Airport to Missouri (average of $129). Flying from New York LaGuardia Airport to Missouri in March is currently the most expensive (average of $259). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.

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Alternative routes for LaGuardia to Missouri

See prices for flight routes from nearby airports that may be better suited for you.
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John F Kennedy Intl to San Francisco flights
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John F Kennedy Intl to O'Hare Intl flights
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LaGuardia to Atlanta flights
Newark to Tampa flights
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LaGuardia to Tampa flights
John F Kennedy Intl to West Palm Beach flights
Newark to West Palm Beach flights
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Newark to Denver flights
Newark to New Orleans flights
John F Kennedy Intl to Tampa flights
Newark to Nashville flights
LaGuardia to Denver flights
LaGuardia to Hobby flights
LaGuardia to New Orleans flights
Newark to Sky Harbor Intl flights
Stewart to San Francisco flights
Newark to Hobby flights
John F Kennedy Intl to Denver flights
Newark to Midway flights
John F Kennedy Intl to Nashville flights
John F Kennedy Intl to New Orleans flights
John F Kennedy Intl to Sky Harbor Intl flights
John F Kennedy Intl to Hobby flights
LaGuardia to Nashville flights

Top 5 airlines flying from LaGuardia to Missouri

Discover the top 5 airlines that operate flights from LaGuardia to Missouri. Compare their services, reliability, and customer satisfaction ratings to choose the airline that best suits your travel preferences and needs. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated April 18, 2026.
AirlineCheapestAverageFlexibilityOn-time
FrontierCheapest$146Average$201FlexibilityNo cancel feeOn-time62%
SouthwestCheapest$207Average$385FlexibilityNo cancel feeOn-time63%
DeltaCheapest$218Average$375FlexibilityNo cancel feeOn-timeN/A
American AirlinesCheapest$241Average$385FlexibilityNo cancel feeOn-time71%
United AirlinesCheapest$364Average$587FlexibilityNo cancel feeOn-time69%

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