$119+ Cheap flights from LaGuardia, NY (LGA) to Missouri
This is the cheapest one-way flight price found by a Cheapflights user in the last 72 hours by searching for a flight departing on 5/7. Fares are subject to change and may not be available on all flights or dates of travel.
LGA — STL
Mar 25 — Apr 11
1 adult, Economy
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1. Tell us where you want to go
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Cheapest flights from LaGuardia to MissouriExplore the most affordable flight options available from LaGuardia to Missouri. Find the lowest fares from popular airlines and budget airlines, with prices last updated on February 23, 2026.
Explore the most affordable flight options available from LaGuardia to Missouri. Find the lowest fares from popular airlines and budget airlines, with prices last updated on February 23, 2026.
This Kiwi.com deal was found by Cheapflights users on 2/20. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 5/1410:00 pm
LGA
- STL
1 stop9h 50m
Frontier
Fri 5/158:12 pm
STL
- LGA
2 stops20h 18m
Frontier
Deal found 2/20![Frontier logo]()
$274
This Frontier deal was found by Cheapflights users on 2/21. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Frontier is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 3/64:59 pm
LGA
- STL
1 stop7h 20m
Frontier
Mon 3/92:09 pm
STL
- LGA
1 stop8h 06m
Frontier
Deal found 2/21![Frontier logo]()
$275
This American Airlines deal was found by Cheapflights users on 2/18. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 10/305:59 am
LGA
- STL
1 stop8h 04m
American Airlines
Fri 10/303:03 pm
STL
- LGA
Nonstop2h 26m
American Airlines
Deal found 2/18![American Airlines logo]()
$276
This CheapOair deal was found by Cheapflights users on 2/19. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure CheapOair is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 3/410:00 pm
LGA
- STL
1 stop26h 59m
Frontier
Sun 3/87:52 am
STL
- LGA
1 stop26h 37m
Frontier
Deal found 2/19![Frontier logo]()
$277
This Delta deal was found by Cheapflights users on 2/20. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 9/46:59 am
LGA
- STL
Nonstop2h 45m
Delta
Tue 9/86:00 am
STL
- LGA
Nonstop2h 27m
Delta
Deal found 2/20![Delta logo]()
$278
This American Airlines deal was found by Cheapflights users on 2/21. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 4/134:12 pm
LGA
- STL
1 stop8h 34m
American Airlines
Thu 4/166:35 am
STL
- LGA
Nonstop2h 34m
American Airlines
Deal found 2/21![American Airlines logo]()
$279
This Southwest deal was found by Cheapflights users on 2/22. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 4/186:55 am
LGA
- STL
2 stops13h 50m
Southwest
Sat 4/256:10 am
STL
- LGA
2 stops9h 05m
Southwest
Deal found 2/22![Southwest logo]()
$281
This Kiwi.com deal was found by Cheapflights users on 2/19. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 3/116:30 am
LGA
- SGF
1 stop11h 02m
Multiple Airlines
Tue 3/1710:50 am
SGF
- LGA
2 stops31h 40m
Multiple Airlines
Deal found 2/19![Multiple Airlines logo]()
$281
This CheapOair deal was found by Cheapflights users on 2/19. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure CheapOair is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 2/2112:30 pm
LGA
- STL
1 stop12h 29m
Frontier
Tue 3/33:49 pm
STL
- LGA
1 stop28h 16m
Frontier
Deal found 2/19![Frontier logo]()
$282
This Mytrip deal was found by Cheapflights users on 2/19. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Mytrip is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 2/248:44 pm
LGA
- STL
1 stop11h 07m
Frontier
Fri 2/273:49 pm
STL
- LGA
1 stop18h 19m
Frontier
Deal found 2/19![Frontier logo]()
$283
This Delta deal was found by Cheapflights users on 2/20. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 4/110:30 am
LGA
- STL
Nonstop2h 52m
Delta
Sun 4/56:10 am
STL
- LGA
Nonstop2h 24m
Delta
Deal found 2/20![Delta logo]()
$285
This Southwest deal was found by Cheapflights users on 2/20. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 3/246:05 am
LGA
- STL
1 stop9h 30m
Southwest
Tue 3/244:00 pm
STL
- LGA
1 stop6h 20m
Southwest
Deal found 2/20![Southwest logo]()
$286
Best flights from LaGuardia to MissouriDiscover carefully curated flight deals from LaGuardia to Missouri that have cost, travel time, and layovers in mind to ensure you get the best travel experience. Data last updated February 23, 2026.
Discover carefully curated flight deals from LaGuardia to Missouri that have cost, travel time, and layovers in mind to ensure you get the best travel experience. Data last updated February 23, 2026.
This Delta deal was found by Cheapflights users on 2/21. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 3/266:55 am
LGA
- STL
Nonstop2h 49m
Delta
Tue 3/315:15 pm
STL
- LGA
Nonstop2h 20m
Delta
Deal found 2/21![Delta logo]()
$278
This Southwest deal was found by Cheapflights users on 2/20. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 4/712:00 pm
LGA
- STL
Nonstop2h 50m
Southwest
Sat 4/116:00 am
STL
- LGA
Nonstop2h 20m
Southwest
Deal found 2/20![Southwest logo]()
$279
This Kiwi.com deal was found by Cheapflights users on 2/19. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 3/116:30 am
LGA
- SGF
1 stop11h 02m
Multiple Airlines
Tue 3/1710:50 am
SGF
- LGA
2 stops31h 40m
Multiple Airlines
Deal found 2/19![Multiple Airlines logo]()
$281
This United Airlines deal was found by Cheapflights users on 2/21. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 3/194:55 pm
LGA
- JLN
1 stop7h 33m
United Airlines
Wed 3/258:54 am
JLN
- LGA
1 stop6h 19m
United Airlines
Deal found 2/21![United Airlines logo]()
$299
This Mytrip deal was found by Cheapflights users on 2/18. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Mytrip is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 3/315:45 am
LGA
- MCI
2 stops19h 08m
Spirit Airlines
Wed 4/15:45 am
MCI
- LGA
2 stops17h 13m
Spirit Airlines
Deal found 2/18![Spirit Airlines logo]()
$310
This American Airlines deal was found by Cheapflights users on 2/19. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 3/512:00 pm
LGA
- COU
1 stop9h 19m
American Airlines
Sun 3/86:00 am
COU
- LGA
1 stop10h 59m
American Airlines
Deal found 2/19![American Airlines logo]()
$414
This Delta deal was found by Cheapflights users on 2/21. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 3/256:55 am
LGA
- STL
Nonstop2h 49m
Delta
Tue 3/3110:50 am
STL
- LGA
1 stop4h 00m
Delta
Deal found 2/21![Delta logo]()
$288
This Southwest deal was found by Cheapflights users on 2/20. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 4/66:00 am
LGA
- STL
Nonstop3h 00m
Southwest
Mon 4/138:00 pm
STL
- LGA
Nonstop2h 25m
Southwest
Deal found 2/20![Southwest logo]()
$297
This United Airlines deal was found by Cheapflights users on 2/19. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 3/53:10 pm
LGA
- JLN
1 stop9h 18m
United Airlines
Sat 3/78:54 am
JLN
- LGA
1 stop7h 19m
United Airlines
Deal found 2/19![United Airlines logo]()
$304
This Delta deal was found by Cheapflights users on 2/21. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 5/67:38 am
LGA
- STL
Nonstop2h 49m
Delta
Fri 6/195:30 pm
STL
- LGA
1 stop5h 20m
Delta
Deal found 2/21![Delta logo]()
$288
This Kiwi.com deal was found by Cheapflights users on 2/18. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 3/276:00 am
LGA
- MCI
1 stop11h 23m
Multiple Airlines
Sun 3/2912:24 pm
MCI
- LGA
2 stops24h 36m
Multiple Airlines
Deal found 2/18![Multiple Airlines logo]()
$332
This United Airlines deal was found by Cheapflights users on 2/19. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 3/74:55 pm
LGA
- JLN
1 stop7h 33m
United Airlines
Wed 3/118:54 am
JLN
- LGA
1 stop6h 19m
United Airlines
Deal found 2/19![United Airlines logo]()
$304
This Southwest deal was found by Cheapflights users on 2/19. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 3/136:00 am
LGA
- STL
Nonstop3h 00m
Southwest
Wed 3/182:00 pm
STL
- LGA
Nonstop2h 20m
Southwest
Deal found 2/19![Southwest logo]()
$305
This Delta deal was found by Cheapflights users on 2/19. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 3/127:59 am
LGA
- SGF
1 stop8h 11m
Delta
Wed 3/183:56 pm
SGF
- LGA
1 stop4h 46m
Delta
Deal found 2/19![Delta logo]()
$294
This United Airlines deal was found by Cheapflights users on 2/19. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 3/61:15 pm
LGA
- SGF
1 stop5h 18m
United Airlines
Tue 3/101:27 pm
SGF
- LGA
1 stop7h 02m
United Airlines
Deal found 2/19![United Airlines logo]()
$309
This Delta deal was found by Cheapflights users on 2/22. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 4/136:00 pm
LGA
- STL
1 stop6h 36m
Delta
Tue 4/146:25 am
STL
- LGA
Nonstop2h 30m
Delta
Deal found 2/22![Delta logo]()
$295
This American Airlines deal was found by Cheapflights users on 2/19. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 3/510:29 am
LGA
- COU
1 stop8h 36m
American Airlines
Mon 3/96:00 am
COU
- LGA
1 stop13h 15m
American Airlines
Deal found 2/19![American Airlines logo]()
$414
This Kiwi.com deal was found by Cheapflights users on 2/19. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 4/136:00 am
LGA
- SGF
1 stop14h 33m
Multiple Airlines
Mon 4/205:41 pm
SGF
- LGA
1 stop21h 23m
Multiple Airlines
Deal found 2/19![Multiple Airlines logo]()
$380
This Southwest deal was found by Cheapflights users on 2/19. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 4/14:25 pm
LGA
- MCI
1 stop7h 15m
Southwest
Sat 4/46:30 pm
MCI
- LGA
Nonstop2h 40m
Southwest
Deal found 2/19![Southwest logo]()
$349
This Delta deal was found by Cheapflights users on 2/19. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 3/136:55 am
LGA
- STL
Nonstop2h 49m
Delta
Tue 3/176:10 am
STL
- LGA
Nonstop2h 24m
Delta
Deal found 2/19![Delta logo]()
$305
This Southwest deal was found by Cheapflights users on 2/19. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 3/238:55 pm
LGA
- MCI
Nonstop3h 25m
Southwest
Wed 3/258:20 am
MCI
- LGA
1 stop4h 30m
Southwest
Deal found 2/19![Southwest logo]()
$349
This Delta deal was found by Cheapflights users on 2/19. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 5/59:20 am
LGA
- STL
1 stop4h 45m
Delta
Fri 5/85:45 pm
STL
- LGA
Nonstop2h 29m
Delta
Deal found 2/19![Delta logo]()
$307
This United Airlines deal was found by Cheapflights users on 2/19. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 3/196:10 am
LGA
- SGF
1 stop5h 36m
United Airlines
Wed 3/257:45 am
SGF
- LGA
1 stop6h 29m
United Airlines
Deal found 2/19![United Airlines logo]()
$375
This Southwest deal was found by Cheapflights users on 2/18. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 4/18:55 am
LGA
- MCI
1 stop5h 35m
Southwest
Mon 4/66:50 am
MCI
- LGA
Nonstop2h 40m
Southwest
Deal found 2/18![Southwest logo]()
$349
This Delta deal was found by Cheapflights users on 2/19. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 4/247:00 pm
LGA
- STL
1 stop5h 36m
Delta
Sun 4/266:25 am
STL
- LGA
Nonstop2h 30m
Delta
Deal found 2/19![Delta logo]()
$307
This Southwest deal was found by Cheapflights users on 2/21. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 3/316:50 am
LGA
- MCI
2 stops7h 25m
Southwest
Thu 4/25:10 pm
MCI
- LGA
Nonstop2h 40m
Southwest
Deal found 2/21![Southwest logo]()
$354
This United Airlines deal was found by Cheapflights users on 2/22. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 2/2711:15 am
LGA
- COU
2 stops10h 09m
United Airlines
Sun 3/18:00 am
COU
- LGA
1 stop6h 19m
United Airlines
Deal found 2/22![United Airlines logo]()
$404
This American Airlines deal was found by Cheapflights users on 2/21. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 3/811:07 am
LGA
- COU
1 stop10h 12m
American Airlines
Thu 3/126:00 am
COU
- LGA
1 stop8h 04m
American Airlines
Deal found 2/21![American Airlines logo]()
$542
This Delta deal was found by Cheapflights users on 2/22. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 4/167:38 am
LGA
- STL
Nonstop2h 49m
Delta
Sun 4/196:00 am
STL
- LGA
1 stop4h 43m
Delta
Deal found 2/22![Delta logo]()
$314
This United Airlines deal was found by Cheapflights users on 2/20. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 4/248:20 pm
LGA
- SGF
1 stop5h 16m
United Airlines
Mon 4/276:35 pm
SGF
- LGA
1 stop14h 43m
United Airlines
Deal found 2/20![United Airlines logo]()
$407
Last-minute flights from LaGuardia to MissouriDiscover last-minute flight deals from LaGuardia to Missouri. Data last updated February 23, 2026 and is based on user searches.
Discover last-minute flight deals from LaGuardia to Missouri. Data last updated February 23, 2026 and is based on user searches.
This CheapOair deal was found by Cheapflights users on 2/19. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure CheapOair is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 2/2112:30 pm
LGA
- STL
1 stop12h 29m
Frontier
Tue 3/33:49 pm
STL
- LGA
1 stop28h 16m
Frontier
Deal found 2/19![Frontier logo]()
$282
This Mytrip deal was found by Cheapflights users on 2/19. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Mytrip is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 2/248:44 pm
LGA
- STL
1 stop11h 07m
Frontier
Fri 2/273:49 pm
STL
- LGA
1 stop18h 19m
Frontier
Deal found 2/19![Frontier logo]()
$283
This CheapOair deal was found by Cheapflights users on 2/19. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure CheapOair is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 3/410:00 pm
LGA
- STL
1 stop26h 59m
Frontier
Sun 3/87:52 am
STL
- LGA
1 stop26h 37m
Frontier
Deal found 2/19![Frontier logo]()
$277
This CheapOair deal was found by Cheapflights users on 2/19. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure CheapOair is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 3/612:30 pm
LGA
- STL
1 stop19h 32m
Frontier
Sun 3/84:51 pm
STL
- LGA
1 stop17h 38m
Frontier
Deal found 2/19![Frontier logo]()
$281
This Priceline deal was found by Cheapflights users on 2/22. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Priceline is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 3/74:59 pm
LGA
- STL
1 stop7h 20m
Frontier
Mon 3/92:09 pm
STL
- LGA
1 stop8h 06m
Frontier
Deal found 2/22![Frontier logo]()
$275
This Kiwi.com deal was found by Cheapflights users on 2/19. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 3/116:30 am
LGA
- SGF
1 stop11h 02m
Multiple Airlines
Tue 3/1710:50 am
SGF
- LGA
2 stops31h 40m
Multiple Airlines
Deal found 2/19![Multiple Airlines logo]()
$281
This Delta deal was found by Cheapflights users on 2/19. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 3/1210:25 am
LGA
- STL
Nonstop2h 54m
Delta
Tue 3/171:34 pm
STL
- LGA
Nonstop2h 26m
Delta
Deal found 2/19![Delta logo]()
$289
This Kiwi.com deal was found by Cheapflights users on 2/20. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 3/236:00 am
LGA
- STL
1 stop8h 34m
Frontier
Mon 3/234:51 pm
STL
- LGA
1 stop21h 39m
Frontier
Deal found 2/20![Frontier logo]()
$287
This Southwest deal was found by Cheapflights users on 2/20. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 3/246:05 am
LGA
- STL
1 stop9h 30m
Southwest
Tue 3/244:00 pm
STL
- LGA
1 stop6h 20m
Southwest
Deal found 2/20![Southwest logo]()
$286
This Delta deal was found by Cheapflights users on 2/21. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 3/2510:25 am
LGA
- STL
Nonstop2h 54m
Delta
Sun 3/296:10 am
STL
- LGA
Nonstop2h 24m
Delta
Deal found 2/21![Delta logo]()
$285
This Delta deal was found by Cheapflights users on 2/21. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 3/256:55 am
LGA
- STL
Nonstop2h 49m
Delta
Mon 3/304:21 pm
STL
- LGA
1 stop5h 22m
Delta
Deal found 2/21![Delta logo]()
$288
This Southwest deal was found by Cheapflights users on 2/19. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 3/276:00 am
LGA
- STL
Nonstop3h 00m
Southwest
Sat 3/287:40 pm
STL
- LGA
Nonstop2h 15m
Southwest
Deal found 2/19![Southwest logo]()
$278
One-way flights from LaGuardia to MissouriSearch for one-way flight options from LaGuardia to Missouri. Find affordable one-way fares based on user searches. Data last updated February 23, 2026.
Search for one-way flight options from LaGuardia to Missouri. Find affordable one-way fares based on user searches. Data last updated February 23, 2026.
This Kiwi.com deal was found by Cheapflights users on 2/18. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 5/76:00 pm
LGA
- MCI
1 stop6h 57m
Spirit Airlines
Deal found 2/18![Spirit Airlines logo]()
$119
This Kiwi.com deal was found by Cheapflights users on 2/19. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 4/84:59 pm
LGA
- MCI
1 stop19h 30m
Spirit Airlines
Deal found 2/19![Spirit Airlines logo]()
$120
This Cheapflightsfares deal was found by Cheapflights users on 2/18. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Cheapflightsfares is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 4/256:00 pm
LGA
- MCI
1 stop6h 57m
Spirit Airlines
Deal found 2/18![Spirit Airlines logo]()
$121
This Kiwi.com deal was found by Cheapflights users on 2/19. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 5/510:55 pm
LGA
- MCI
2 stops26h 02m
Multiple Airlines
Deal found 2/19![Multiple Airlines logo]()
$122
This Kiwi.com deal was found by Cheapflights users on 2/19. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 5/1210:55 pm
LGA
- MCI
2 stops26h 02m
Multiple Airlines
Deal found 2/19![Multiple Airlines logo]()
$124
This Mytrip deal was found by Cheapflights users on 2/20. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Mytrip is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 4/137:59 pm
LGA
- MCI
2 stops16h 30m
Spirit Airlines
Deal found 2/20![Spirit Airlines logo]()
$125
This Kiwi.com deal was found by Cheapflights users on 2/19. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 4/278:25 pm
LGA
- MCI
1 stop28h 32m
Multiple Airlines
Deal found 2/19![Multiple Airlines logo]()
$126
This Kiwi.com deal was found by Cheapflights users on 2/19. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 5/84:37 pm
LGA
- MCI
1 stop19h 32m
Spirit Airlines
Deal found 2/19![Spirit Airlines logo]()
$127
This Kiwi.com deal was found by Cheapflights users on 2/19. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 5/118:25 pm
LGA
- MCI
1 stop28h 32m
Multiple Airlines
Deal found 2/19![Multiple Airlines logo]()
$128
This Kiwi.com deal was found by Cheapflights users on 2/19. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 4/208:25 pm
LGA
- MCI
1 stop28h 32m
Multiple Airlines
Deal found 2/19![Multiple Airlines logo]()
$129
This Kiwi.com deal was found by Cheapflights users on 2/19. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 5/145:45 am
LGA
- MCI
1 stop30h 24m
Spirit Airlines
Deal found 2/19![Spirit Airlines logo]()
$130
This Kiwi.com deal was found by Cheapflights users on 2/19. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 3/256:20 am
LGA
- MCI
2 stops35h 35m
Frontier
Deal found 2/19![Frontier logo]()
$131
Find flight deals from LaGuardia to Missouri
Keep the following information in mind while searching for LaGuardia to Missouri flight deals. Data was last updated February 23, 2026.
Most accurate provider | FlightHub 3 stars |
|---|---|
Most trusted provider | FlightHub 3 stars |
Round-trip from | $274 (Kiwi.com) |
One-way from | $119 (Kiwi.com) |
Popular in | November |
Cheapest in | August |
Average price | $366 |
Good round-trip deal | $318 or less |
Good one-way deal | $178 or less |
Cheapflights Fare Finder
Customize your flight search to find flights from LaGuardia to Missouri that fit within your specific budget. Explore options based on user searches and filter the results based on your desired price range. Find flights that match your budget for a cost-effective journey. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated February 23, 2026.
Use the filters below to find and compare flights from New York LaGuardia Airport to Missouri that are best for you.
Fly from
LaGuardia
Fly to
Missouri
Route
Depart
Return
Price
New YorkSt. Louis
LGA - STL
LGASTL
New York LaGuardia
Thu 3/26
6:55 am-8:44 am
Nonstop2h 49m
Lambert-St Louis
Tue 3/31
5:15 pm-8:35 pm
Nonstop2h 20m
$278
New YorkSt. Louis
LGA - STL
LGASTL
New York LaGuardia
Tue 4/7
12:00 pm-1:50 pm
Nonstop2h 50m
Lambert-St Louis
Sat 4/11
6:00 am-9:20 am
Nonstop2h 20m
$279
New YorkSpringfield
LGA - SGF
LGASGF
New York LaGuardia
Wed 3/11
6:30 am-4:32 pm
1 stop11h 02m
Springfield-Branson
Tue 3/17
10:50 am-7:30 pm
2 stops31h 40m
$281
New YorkSt. Louis
LGA - STL
LGASTL
New York LaGuardia
Wed 3/25
6:55 am-8:44 am
Nonstop2h 49m
Lambert-St Louis
Tue 3/31
10:50 am-3:50 pm
1 stop4h 00m
$288
New YorkSt. Louis
LGA - STL
LGASTL
New York LaGuardia
Wed 5/6
7:38 am-9:27 am
Nonstop2h 49m
Lambert-St Louis
Fri 6/19
5:30 pm-11:50 pm
1 stop5h 20m
$288
New YorkSpringfield
LGA - SGF
LGASGF
New York LaGuardia
Thu 3/12
7:59 am-3:10 pm
1 stop8h 11m
Springfield-Branson
Wed 3/18
3:56 pm-9:42 pm
1 stop4h 46m
$294
New YorkSt. Louis
LGA - STL
LGASTL
New York LaGuardia
Mon 4/13
6:00 pm-11:36 pm
1 stop6h 36m
Lambert-St Louis
Tue 4/14
6:25 am-9:55 am
Nonstop2h 30m
$295
New YorkSt. Louis
LGA - STL
LGASTL
New York LaGuardia
Mon 4/6
6:00 am-8:00 am
Nonstop3h 00m
Lambert-St Louis
Mon 4/13
8:00 pm-11:25 pm
Nonstop2h 25m
$297
New YorkJoplin
LGA - JLN
LGAJLN
New York LaGuardia
Thu 3/19
4:55 pm-11:28 pm
1 stop7h 33m
Joplin
Wed 3/25
8:54 am-4:13 pm
1 stop6h 19m
$299
New YorkJoplin
LGA - JLN
LGAJLN
New York LaGuardia
Thu 3/5
3:10 pm-11:28 pm
1 stop9h 18m
Joplin
Sat 3/7
8:54 am-5:13 pm
1 stop7h 19m
$304
Showing 1-10 of 60 results
Best time to book a flight from LaGuardia to Missouri
Have a flexible travel schedule? Discover the best time to fly to Missouri from LaGuardia with our price prediction graph.
LGA-STL
LGA-SGF
LGA-MCI
LGA-COU
LGA-JLN
Estimated round-trip price
Rates are based on past data. Find the cheapest month and day to book your flight based on your travel requirements, then search for cheap deals.
Cheapflights Insights
Everything you need to know about your flight from New York LaGuardia Airport to Missouri
LGA-USMO
LGA-STL
LGA-SGF
LGA-MCI
LGA-COU
What is the cheapest month to book a flight from New York LaGuardia Airport to Missouri?
Currently, September is the cheapest month in which you can book a flight from New York LaGuardia Airport to Missouri (average of $146). Flying from New York LaGuardia Airport to Missouri in February is currently the most expensive (average of $273). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.
What is the cheapest time of day to fly from LGA to MO?
Find hourly flight availability from LaGuardia to Missouri. Discover flight options and departure times throughout the day, allowing you to choose a departure time that suits your schedule. Data last updated February 23, 2026.
Unlike in the evening, when flights are generally more expensive, you can save up to 3% on flights from New York LaGuardia Airport to Missouri by exploring options for tickets in the morning.
What is the cheapest day to fly from New York LaGuardia Airport to Missouri?
Use this chart to determine the cheapest time to fly round-trip from LaGuardia to Missouri. Price data was last updated on February 21, 2026.
Travelers seeking maximum savings on their New York LaGuardia Airport to Missouri flight should consider departing on Saturday evenings when fares are most often at their lowest. Sunday evenings flights should be avoided if possible as fares are typically the most expensive at this time.
Weekly flight availability from New York LaGuardia Airport to Missouri
Explore weekly flight availability from LaGuardia to Missouri. Discover flights operating on different days of the week, giving you the flexibility to choose a travel day that best fits your plans. Compare info to find the most convenient option for your journey. Data last updated February 23, 2026.
The most flights from LGA to USMO are scheduled on a Friday (14 on average). You will have fewer flight options on Saturday, which is when the least amount of flights are scheduled (5 on average).
Reviews of airlines servicing Missouri
Get insights into the airlines that provide service to Missouri. Read reviews, discover amenities, and learn about the overall travel experience offered by airlines. Use this information to make informed decisions when choosing an airline for your flight to Missouri. Reviews last updated February 23, 2026.
See what other customers who have flown with Southwest, Delta, and United Airlines from New York LaGuardia Airport to Missouri have to say. Users can see the overall rating for each airline as well as how each is rated in terms of entertainment options, comfort, food, crew/service, and boarding process.
Food
7.0
Crew
8.6
Boarding
8.1
Comfort
8.0
Overall
8.0
Entertainment
7.5
Reviews
1 / 20
2.0
MediocreThomas,Dec 2025
SEA - DEN
Food
7.0
Crew
8.6
Boarding
8.1
Comfort
8.0
Overall
8.0
Entertainment
7.5
Reviews
1 / 20
2.0
MediocreThomas,Dec 2025
SEA - DEN
Food
7.0
Crew
8.6
Boarding
8.1
Comfort
8.0
Overall
8.0
Entertainment
7.5
Reviews
1 / 20
2.0
MediocreThomas,Dec 2025
SEA - DEN
Food
7.0
Crew
8.6
Boarding
8.1
Comfort
8.0
Overall
8.0
Entertainment
7.5
Reviews
1 / 20
2.0
MediocreThomas,Dec 2025
SEA - DEN
Food
7.0
Crew
8.6
Boarding
8.1
Comfort
8.0
Overall
8.0
Entertainment
7.5
Reviews
1 / 20
2.0
MediocreThomas,Dec 2025
SEA - DEN
Food
7.0
Crew
8.6
Boarding
8.1
Comfort
8.0
Overall
8.0
Entertainment
7.5
Reviews
1 / 20
2.0
MediocreThomas,Dec 2025
SEA - DEN
Related info for your journey
Find useful and relevant information for your journey from LaGuardia to Missouri. Access travel guides, tips, and recommendations to enhance your travel experience. Get information about local attractions, weather, transportation options, and more.
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Alternative routes for LaGuardia to Missouri
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Complete your trip
Complete your trip to Missouri by adding a car rental and/or hotel reservation to your travel itinerary.
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Find flights from LaGuardia to Missouri, based on your preferred cabin class, be it economy, premium economy, business, or first class.
LaGuardia and Missouri flights
Browse other LaGuardia and Missouri flight options. Last updated on February 23, 2026.
Popular flight searches
Check out other popular destinations found by fellow travelers in 2026
LaGuardia to Missouri flights
Consider these flights traveling from LaGuardia to Missouri.
Top 5 airlines flying from LaGuardia to Missouri
Discover the top 5 airlines that operate flights from LaGuardia to Missouri. Compare their services, reliability, and customer satisfaction ratings to choose the airline that best suits your travel preferences and needs. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated February 23, 2026.
| Airline | Cheapest | Average | Flexibility | On-time |
|---|---|---|---|---|
| Cheapest$136 | Average$212 | FlexibilityNo cancel fee | On-time62% | |
| Cheapest$194 | Average$362 | FlexibilityNo cancel fee | On-timeN/A | |
| Cheapest$197 | Average$356 | FlexibilityNo cancel fee | On-time63% | |
| Cheapest$217 | Average$401 | FlexibilityNo cancel fee | On-time71% | |
| Cheapest$364 | Average$553 | FlexibilityNo cancel fee | On-time69% |