$150+ Cheap flights from LaGuardia, NY (LGA) to Missouri
This is the cheapest one-way flight price found by a Cheapflights user in the last 72 hours by searching for a flight departing on 6/6. Fares are subject to change and may not be available on all flights or dates of travel.
LGA — STL
May 10 — May 171
Round-trip
1 adult, Economy
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Cheapest flights from LaGuardia to MissouriExplore the most affordable flight options available from LaGuardia to Missouri. Find the lowest fares from popular airlines and budget airlines, with prices last updated on April 10, 2026.
Explore the most affordable flight options available from LaGuardia to Missouri. Find the lowest fares from popular airlines and budget airlines, with prices last updated on April 10, 2026.
This American Airlines deal was found by Cheapflights users on 4/6. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 5/49:09 am
LGA
- STL
Nonstop3h 00m
American Airlines
Wed 5/63:42 pm
STL
- LGA
Nonstop2h 37m
American Airlines
Deal found 4/6![American Airlines logo]()
$294
This Kiwi.com deal was found by Cheapflights users on 4/9. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 4/213:29 pm
LGA
- STL
1 stop8h 50m
Multiple Airlines
Wed 4/228:23 pm
STL
- LGA
2 stops17h 06m
Multiple Airlines
Deal found 4/9![Multiple Airlines logo]()
$295
This Delta deal was found by Cheapflights users on 4/10. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 5/67:38 am
LGA
- STL
Nonstop2h 49m
Delta
Wed 7/812:28 pm
STL
- LGA
Nonstop2h 38m
Delta
Deal found 4/10![Delta logo]()
$296
This Kiwi.com deal was found by Cheapflights users on 4/5. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 4/2510:00 pm
LGA
- STL
1 stop13h 49m
Multiple Airlines
Sun 5/103:33 pm
STL
- LGA
1 stop27h 14m
Multiple Airlines
Deal found 4/5![Multiple Airlines logo]()
$298
This Kiwi.com deal was found by Cheapflights users on 4/9. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 4/2910:59 pm
LGA
- STL
2 stops12h 27m
Frontier
Fri 5/18:23 pm
STL
- LGA
1 stop20h 29m
Frontier
Deal found 4/9![Frontier logo]()
$299
This Southwest deal was found by Cheapflights users on 4/10. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 6/86:30 pm
LGA
- STL
Nonstop3h 10m
Southwest
Tue 6/95:55 pm
STL
- LGA
1 stop4h 00m
Southwest
Deal found 4/10![Southwest logo]()
$300
This Priceline deal was found by Cheapflights users on 4/10. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Priceline is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 4/1710:00 pm
LGA
- STL
1 stop9h 50m
Frontier
Sun 4/1911:16 am
STL
- LGA
1 stop8h 43m
Frontier
Deal found 4/10![Frontier logo]()
$301
This Kiwi.com deal was found by Cheapflights users on 4/7. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 5/145:45 am
LGA
- STL
1 stop10h 03m
Multiple Airlines
Sat 5/167:08 pm
STL
- LGA
1 stop23h 39m
Multiple Airlines
Deal found 4/7![Multiple Airlines logo]()
$302
This Kiwi.com deal was found by Cheapflights users on 4/9. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 4/298:00 am
LGA
- STL
1 stop16h 19m
Multiple Airlines
Sun 5/34:59 pm
STL
- LGA
2 stops16h 01m
Multiple Airlines
Deal found 4/9![Multiple Airlines logo]()
$303
This American Airlines deal was found by Cheapflights users on 4/9. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 10/207:57 am
LGA
- SGF
1 stop5h 45m
American Airlines
Sat 10/245:45 am
SGF
- LGA
1 stop6h 29m
American Airlines
Deal found 4/9![American Airlines logo]()
$303
This Southwest deal was found by Cheapflights users on 4/7. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 5/43:00 pm
LGA
- STL
Nonstop2h 50m
Southwest
Tue 5/121:25 pm
STL
- LGA
1 stop7h 00m
Southwest
Deal found 4/7![Southwest logo]()
$304
This Kiwi.com deal was found by Cheapflights users on 4/8. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 5/75:45 am
LGA
- STL
1 stop10h 03m
Multiple Airlines
Sun 5/103:33 pm
STL
- LGA
1 stop29h 27m
Multiple Airlines
Deal found 4/8![Multiple Airlines logo]()
$305
Best flights from LaGuardia to MissouriDiscover carefully curated flight deals from LaGuardia to Missouri that have cost, travel time, and layovers in mind to ensure you get the best travel experience. Data last updated April 10, 2026.
Discover carefully curated flight deals from LaGuardia to Missouri that have cost, travel time, and layovers in mind to ensure you get the best travel experience. Data last updated April 10, 2026.
This Kiwi.com deal was found by Cheapflights users on 4/10. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 5/2210:00 pm
LGA
- STL
1 stop11h 55m
Frontier
Mon 5/255:27 pm
STL
- LGA
1 stop28h 47m
Frontier
Deal found 4/10![Frontier logo]()
$306
This Delta deal was found by Cheapflights users on 4/9. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 5/15:30 pm
LGA
- STL
Nonstop2h 56m
Delta
Tue 5/510:07 am
STL
- LGA
Nonstop2h 22m
Delta
Deal found 4/9![Delta logo]()
$332
This Southwest deal was found by Cheapflights users on 4/9. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 5/117:25 am
LGA
- STL
1 stop6h 30m
Southwest
Mon 5/113:50 pm
STL
- LGA
1 stop5h 05m
Southwest
Deal found 4/9![Southwest logo]()
$335
This American Airlines deal was found by Cheapflights users on 4/10. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 4/242:12 pm
LGA
- COU
1 stop8h 18m
American Airlines
Mon 4/276:00 am
COU
- LGA
1 stop5h 11m
American Airlines
Deal found 4/10![American Airlines logo]()
$378
This United Airlines deal was found by Cheapflights users on 4/9. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 4/216:10 am
LGA
- SGF
1 stop5h 38m
United Airlines
Tue 5/56:00 am
SGF
- LGA
1 stop7h 18m
United Airlines
Deal found 4/9![United Airlines logo]()
$378
This Delta deal was found by Cheapflights users on 4/8. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 6/161:41 pm
LGA
- STL
Nonstop2h 51m
Delta
Sun 6/216:05 am
STL
- LGA
Nonstop2h 33m
Delta
Deal found 4/8![Delta logo]()
$341
This Southwest deal was found by Cheapflights users on 4/5. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 6/136:05 am
LGA
- STL
1 stop9h 50m
Southwest
Sun 6/145:45 am
STL
- LGA
Nonstop2h 20m
Southwest
Deal found 4/5![Southwest logo]()
$360
This Delta deal was found by Cheapflights users on 4/10. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 5/67:59 am
LGA
- MCI
1 stop6h 59m
Delta
Mon 5/116:50 pm
MCI
- LGA
Nonstop2h 56m
Delta
Deal found 4/10![Delta logo]()
$348
This United Airlines deal was found by Cheapflights users on 4/8. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 4/238:05 am
LGA
- JLN
1 stop6h 07m
United Airlines
Mon 4/271:58 pm
JLN
- LGA
2 stops8h 32m
United Airlines
Deal found 4/8![United Airlines logo]()
$390
This Southwest deal was found by Cheapflights users on 4/6. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 7/76:30 am
LGA
- STL
Nonstop2h 35m
Southwest
Fri 7/105:35 pm
STL
- LGA
1 stop4h 50m
Southwest
Deal found 4/6![Southwest logo]()
$364
This United Airlines deal was found by Cheapflights users on 4/9. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 4/214:29 pm
LGA
- SGF
1 stop6h 35m
United Airlines
Tue 4/2811:23 am
SGF
- LGA
1 stop5h 55m
United Airlines
Deal found 4/9![United Airlines logo]()
$393
This Delta deal was found by Cheapflights users on 4/6. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 5/286:00 am
LGA
- MCI
1 stop6h 16m
Delta
Tue 6/26:00 am
MCI
- LGA
Nonstop2h 52m
Delta
Deal found 4/6![Delta logo]()
$362
This Southwest deal was found by Cheapflights users on 4/7. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 4/246:35 pm
LGA
- STL
Nonstop2h 55m
Southwest
Tue 4/287:35 pm
STL
- LGA
Nonstop2h 25m
Southwest
Deal found 4/7![Southwest logo]()
$365
This American Airlines deal was found by Cheapflights users on 4/9. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 5/246:09 pm
LGA
- COU
1 stop5h 37m
American Airlines
Sun 5/317:16 am
COU
- LGA
1 stop6h 51m
American Airlines
Deal found 4/9![American Airlines logo]()
$443
This United Airlines deal was found by Cheapflights users on 4/9. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 4/243:20 pm
LGA
- JLN
2 stops9h 24m
United Airlines
Tue 4/288:56 am
JLN
- LGA
1 stop7h 17m
United Airlines
Deal found 4/9![United Airlines logo]()
$394
This Southwest deal was found by Cheapflights users on 4/10. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 5/166:00 am
LGA
- STL
Nonstop2h 45m
Southwest
Sat 5/1610:35 am
STL
- LGA
2 stops8h 15m
Southwest
Deal found 4/10![Southwest logo]()
$367
This Delta deal was found by Cheapflights users on 4/10. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 5/87:30 am
LGA
- MCI
Nonstop3h 15m
Delta
Tue 5/126:30 am
MCI
- LGA
1 stop6h 34m
Delta
Deal found 4/10![Delta logo]()
$371
This United Airlines deal was found by Cheapflights users on 4/10. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 4/245:15 pm
LGA
- SGF
1 stop5h 49m
United Airlines
Sun 4/266:15 am
SGF
- LGA
1 stop7h 14m
United Airlines
Deal found 4/10![United Airlines logo]()
$394
This Southwest deal was found by Cheapflights users on 4/8. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 5/73:25 pm
LGA
- MCI
Nonstop3h 20m
Southwest
Tue 5/122:10 pm
MCI
- LGA
2 stops7h 20m
Southwest
Deal found 4/8![Southwest logo]()
$367
This Delta deal was found by Cheapflights users on 4/9. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 4/308:29 am
LGA
- MCI
Nonstop3h 21m
Delta
Mon 5/47:29 pm
MCI
- LGA
Nonstop2h 48m
Delta
Deal found 4/9![Delta logo]()
$373
This United Airlines deal was found by Cheapflights users on 4/6. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 5/36:10 am
LGA
- SGF
1 stop5h 30m
United Airlines
Tue 5/128:50 am
SGF
- LGA
1 stop9h 16m
United Airlines
Deal found 4/6![United Airlines logo]()
$402
This Southwest deal was found by Cheapflights users on 4/6. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 7/106:30 pm
LGA
- STL
Nonstop3h 10m
Southwest
Sun 7/125:45 am
STL
- LGA
Nonstop2h 20m
Southwest
Deal found 4/6![Southwest logo]()
$369
This Delta deal was found by Cheapflights users on 4/5. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 6/178:05 pm
LGA
- MCI
Nonstop3h 23m
Delta
Mon 6/221:20 pm
MCI
- LGA
1 stop8h 04m
Delta
Deal found 4/5![Delta logo]()
$375
This Southwest deal was found by Cheapflights users on 4/6. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 7/246:30 pm
LGA
- STL
Nonstop3h 10m
Southwest
Sun 7/267:50 pm
STL
- LGA
Nonstop2h 25m
Southwest
Deal found 4/6![Southwest logo]()
$369
This United Airlines deal was found by Cheapflights users on 4/10. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 5/18:35 pm
LGA
- SGF
1 stop5h 12m
United Airlines
Mon 5/43:10 pm
SGF
- LGA
1 stop7h 13m
United Airlines
Deal found 4/10![United Airlines logo]()
$409
This Delta deal was found by Cheapflights users on 4/8. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 6/247:30 am
LGA
- MCI
Nonstop3h 06m
Delta
Sat 6/276:00 am
MCI
- LGA
Nonstop2h 56m
Delta
Deal found 4/8![Delta logo]()
$385
This Southwest deal was found by Cheapflights users on 4/9. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 7/176:30 pm
LGA
- STL
Nonstop3h 10m
Southwest
Mon 7/207:55 pm
STL
- LGA
Nonstop2h 25m
Southwest
Deal found 4/9![Southwest logo]()
$369
This Delta deal was found by Cheapflights users on 4/5. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 4/256:00 am
LGA
- SGF
1 stop6h 01m
Delta
Tue 4/283:59 pm
SGF
- LGA
1 stop6h 42m
Delta
Deal found 4/5![Delta logo]()
$389
This United Airlines deal was found by Cheapflights users on 4/6. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 4/246:29 pm
LGA
- COU
1 stop7h 04m
United Airlines
Mon 4/273:23 pm
COU
- LGA
2 stops7h 07m
United Airlines
Deal found 4/6![United Airlines logo]()
$429
This Southwest deal was found by Cheapflights users on 4/9. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 5/88:00 pm
LGA
- MCI
Nonstop3h 20m
Southwest
Mon 5/116:10 am
MCI
- LGA
Nonstop2h 40m
Southwest
Deal found 4/9![Southwest logo]()
$379
Last-minute flights from LaGuardia to MissouriDiscover last-minute flight deals from LaGuardia to Missouri. Data last updated April 10, 2026 and is based on user searches.
Discover last-minute flight deals from LaGuardia to Missouri. Data last updated April 10, 2026 and is based on user searches.
This Priceline deal was found by Cheapflights users on 4/10. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Priceline is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 4/1710:00 pm
LGA
- STL
1 stop9h 50m
Frontier
Sun 4/1911:16 am
STL
- LGA
1 stop8h 43m
Frontier
Deal found 4/10![Frontier logo]()
$301
This Kiwi.com deal was found by Cheapflights users on 4/9. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 4/213:29 pm
LGA
- STL
1 stop8h 50m
Multiple Airlines
Wed 4/228:23 pm
STL
- LGA
2 stops17h 06m
Multiple Airlines
Deal found 4/9![Multiple Airlines logo]()
$295
This Kiwi.com deal was found by Cheapflights users on 4/5. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 4/2510:00 pm
LGA
- STL
1 stop13h 49m
Multiple Airlines
Sun 5/103:33 pm
STL
- LGA
1 stop27h 14m
Multiple Airlines
Deal found 4/5![Multiple Airlines logo]()
$298
This Kiwi.com deal was found by Cheapflights users on 4/9. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 4/2910:59 pm
LGA
- STL
2 stops12h 27m
Frontier
Fri 5/18:23 pm
STL
- LGA
1 stop20h 29m
Frontier
Deal found 4/9![Frontier logo]()
$299
This Kiwi.com deal was found by Cheapflights users on 4/9. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 4/298:00 am
LGA
- STL
1 stop16h 19m
Multiple Airlines
Sun 5/34:59 pm
STL
- LGA
2 stops16h 01m
Multiple Airlines
Deal found 4/9![Multiple Airlines logo]()
$303
This American Airlines deal was found by Cheapflights users on 4/5. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 4/295:55 pm
LGA
- SGF
1 stop5h 43m
American Airlines
Wed 5/65:19 am
SGF
- LGA
1 stop6h 58m
American Airlines
Deal found 4/5![American Airlines logo]()
$311
This Kiwi.com deal was found by Cheapflights users on 4/10. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 5/310:00 pm
LGA
- STL
1 stop9h 50m
Multiple Airlines
Tue 5/56:41 pm
STL
- LGA
2 stops14h 19m
Multiple Airlines
Deal found 4/10![Multiple Airlines logo]()
$300
This American Airlines deal was found by Cheapflights users on 4/6. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 5/49:09 am
LGA
- STL
Nonstop3h 00m
American Airlines
Wed 5/63:42 pm
STL
- LGA
Nonstop2h 37m
American Airlines
Deal found 4/6![American Airlines logo]()
$294
This Southwest deal was found by Cheapflights users on 4/7. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 5/43:00 pm
LGA
- STL
Nonstop2h 50m
Southwest
Tue 5/121:25 pm
STL
- LGA
1 stop7h 00m
Southwest
Deal found 4/7![Southwest logo]()
$304
This Delta deal was found by Cheapflights users on 4/10. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 5/67:38 am
LGA
- STL
Nonstop2h 49m
Delta
Wed 7/812:28 pm
STL
- LGA
Nonstop2h 38m
Delta
Deal found 4/10![Delta logo]()
$296
This Kiwi.com deal was found by Cheapflights users on 4/8. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 5/75:45 am
LGA
- STL
1 stop10h 03m
Multiple Airlines
Sun 5/103:33 pm
STL
- LGA
1 stop29h 27m
Multiple Airlines
Deal found 4/8![Multiple Airlines logo]()
$305
This Kiwi.com deal was found by Cheapflights users on 4/7. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 5/145:45 am
LGA
- STL
1 stop10h 03m
Multiple Airlines
Sat 5/167:08 pm
STL
- LGA
1 stop23h 39m
Multiple Airlines
Deal found 4/7![Multiple Airlines logo]()
$302
One-way flights from LaGuardia to MissouriSearch for one-way flight options from LaGuardia to Missouri. Find affordable one-way fares based on user searches. Data last updated April 10, 2026.
Search for one-way flight options from LaGuardia to Missouri. Find affordable one-way fares based on user searches. Data last updated April 10, 2026.
This Kiwi.com deal was found by Cheapflights users on 4/10. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 6/68:42 pm
LGA
- STL
2 stops37h 13m
Multiple Airlines
Deal found 4/10![Multiple Airlines logo]()
$150
This Kiwi.com deal was found by Cheapflights users on 4/6. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 4/238:00 am
LGA
- STL
3 stops24h 54m
Multiple Airlines
Deal found 4/6![Multiple Airlines logo]()
$151
This Kiwi.com deal was found by Cheapflights users on 4/7. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 5/2810:00 pm
LGA
- STL
2 stops22h 23m
Frontier
Deal found 4/7![Frontier logo]()
$153
This Mytrip deal was found by Cheapflights users on 4/9. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Mytrip is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 5/510:59 am
LGA
- STL
3 stops30h 02m
Multiple Airlines
Deal found 4/9![Multiple Airlines logo]()
$154
This Kiwi.com deal was found by Cheapflights users on 4/9. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 4/154:59 pm
LGA
- STL
2 stops31h 20m
Multiple Airlines
Deal found 4/9![Multiple Airlines logo]()
$155
This Kiwi.com deal was found by Cheapflights users on 4/7. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 4/284:42 pm
LGA
- STL
3 stops31h 37m
Multiple Airlines
Deal found 4/7![Multiple Airlines logo]()
$156
This Kiwi.com deal was found by Cheapflights users on 4/9. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 4/268:00 am
LGA
- STL
2 stops31h 36m
Multiple Airlines
Deal found 4/9![Multiple Airlines logo]()
$157
This Delta deal was found by Cheapflights users on 4/10. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 5/216:30 am
LGA
- STL
Nonstop2h 43m
Delta
Deal found 4/10![Delta logo]()
$158
This Mytrip deal was found by Cheapflights users on 4/9. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Mytrip is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 5/610:59 am
LGA
- MCI
2 stops23h 30m
Spirit Airlines
Deal found 4/9![Spirit Airlines logo]()
$158
This Kiwi.com deal was found by Cheapflights users on 4/6. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 5/710:55 pm
LGA
- STL
2 stops21h 28m
Frontier
Deal found 4/6![Frontier logo]()
$159
This Kiwi.com deal was found by Cheapflights users on 4/10. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 4/228:00 am
LGA
- MCI
2 stops27h 58m
Multiple Airlines
Deal found 4/10![Multiple Airlines logo]()
$159
This Kiwi.com deal was found by Cheapflights users on 4/7. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 6/87:00 am
LGA
- STL
1 stop17h 57m
Multiple Airlines
Deal found 4/7![Multiple Airlines logo]()
$160
Find flight deals from LaGuardia to Missouri
Keep the following information in mind while searching for LaGuardia to Missouri flight deals. Data was last updated April 10, 2026.
Most accurate provider | FlightHub 3 stars |
|---|---|
Most trusted provider | FlightHub 3 stars |
Round-trip from | $294 (American Airlines) |
One-way from | $150 (Kiwi.com) |
Popular in | November |
Cheapest in | August |
Average price | $369 |
Good round-trip deal | $337 or less |
Good one-way deal | $184 or less |
Cheapflights Fare Finder
Customize your flight search to find flights from LaGuardia to Missouri that fit within your specific budget. Explore options based on user searches and filter the results based on your desired price range. Find flights that match your budget for a cost-effective journey. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated April 10, 2026.
Use the filters below to find and compare flights from New York LaGuardia Airport to Missouri that are best for you.
Fly from
Fly to
Route
Depart
Return
Cheapest round-trip
New YorkSt. Louis
LGA - STL
LGASTL
New York LaGuardia
Fri 5/22
10:00 pm-8:55 am
1 stop11h 55m
Lambert-St Louis
Mon 5/25
5:27 pm-11:14 pm
1 stop28h 47m
$306
Quickest round-trip
New YorkSt. Louis
LGA - STL
LGASTL
New York LaGuardia
Fri 5/1
5:30 pm-7:26 pm
Nonstop2h 56m
Lambert-St Louis
Tue 5/5
10:07 am-1:29 pm
Nonstop2h 22m
$332
New YorkSt. Louis
LGA - STL
LGASTL
New York LaGuardia
Mon 5/11
7:25 am-12:55 pm
1 stop6h 30m
Lambert-St Louis
Mon 5/11
3:50 pm-9:55 pm
1 stop5h 05m
$335
New YorkSt. Louis
LGA - STL
LGASTL
New York LaGuardia
Tue 6/16
1:41 pm-3:32 pm
Nonstop2h 51m
Lambert-St Louis
Sun 6/21
6:05 am-9:38 am
Nonstop2h 33m
$341
New YorkKansas City
LGA - MCI
LGAMCI
New York LaGuardia
Wed 5/6
7:59 am-1:58 pm
1 stop6h 59m
Kansas City
Mon 5/11
6:50 pm-10:46 pm
Nonstop2h 56m
$348
New YorkSt. Louis
LGA - STL
LGASTL
New York LaGuardia
Sat 6/13
6:05 am-2:55 pm
1 stop9h 50m
Lambert-St Louis
Sun 6/14
5:45 am-9:05 am
Nonstop2h 20m
$360
New YorkKansas City
LGA - MCI
LGAMCI
New York LaGuardia
Thu 5/28
6:00 am-11:16 am
1 stop6h 16m
Kansas City
Tue 6/2
6:00 am-9:52 am
Nonstop2h 52m
$362
New YorkSt. Louis
LGA - STL
LGASTL
New York LaGuardia
Tue 7/7
6:30 am-8:05 am
Nonstop2h 35m
Lambert-St Louis
Fri 7/10
5:35 pm-11:25 pm
1 stop4h 50m
$364
New YorkSt. Louis
LGA - STL
LGASTL
New York LaGuardia
Fri 4/24
6:35 pm-8:30 pm
Nonstop2h 55m
Lambert-St Louis
Tue 4/28
7:35 pm-11:00 pm
Nonstop2h 25m
$365
New YorkSt. Louis
LGA - STL
LGASTL
New York LaGuardia
Sat 5/16
6:00 am-7:45 am
Nonstop2h 45m
Lambert-St Louis
Sat 5/16
10:35 am-7:50 pm
2 stops8h 15m
$367
Showing 1-10 of 60 resultsSorted by cheapest first
Best time to book a flight from LaGuardia to Missouri
Have a flexible travel schedule? Discover the best time to fly to Missouri from LaGuardia with our price prediction graph.
LGA-STL
LGA-MCI
LGA-SGF
LGA-COU
LGA-JLN
Estimated round-trip price
Rates are based on past data. Find the cheapest month and day to book your flight based on your travel requirements, then search for cheap deals.
Cheapflights Insights
Everything you need to know about your flight from New York LaGuardia Airport to Missouri
LGA-USMO
LGA-STL
LGA-MCI
LGA-SGF
LGA-COU
What is the cheapest month to book a flight from New York LaGuardia Airport to Missouri?
Currently, September is the cheapest month in which you can book a flight from New York LaGuardia Airport to Missouri (average of $146). Flying from New York LaGuardia Airport to Missouri in April is currently the most expensive (average of $291). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.
What is the cheapest time of day to fly from LGA to MO?
Find hourly flight availability from LaGuardia to Missouri. Discover flight options and departure times throughout the day, allowing you to choose a departure time that suits your schedule. Data last updated April 10, 2026.
Unlike in the afternoon, when flights are generally more expensive, you can save up to 1% on flights from New York LaGuardia Airport to Missouri by exploring options for tickets in the morning.
What is the cheapest day to fly from New York LaGuardia Airport to Missouri?
Use this chart to determine the cheapest time to fly round-trip from LaGuardia to Missouri. Price data was last updated on April 4, 2026.
Travelers seeking maximum savings on their New York LaGuardia Airport to Missouri flight should consider departing on Saturday evenings when fares are most often at their lowest. Sunday at noon flights should be avoided if possible as fares are typically the most expensive at this time.
How much does it cost to fly round-trip from New York LaGuardia Airport to Missouri?
Reviews of airlines servicing Missouri
Get insights into the airlines that provide service to Missouri. Read reviews, discover amenities, and learn about the overall travel experience offered by airlines. Use this information to make informed decisions when choosing an airline for your flight to Missouri. Reviews last updated April 10, 2026.
See what other customers who have flown with Southwest,Delta, andUnited Airlines from New York LaGuardia Airport to Missouri have to say. Users can see the overall rating for each airline as well as how each is rated in terms of entertainment options, comfort, food, crew/service, and boarding process.
Entertainment
7.5
Overall
8.0
Crew
8.6
Comfort
8.0
Boarding
8.1
Food
7.0
Reviews
1 / 20
2.0
MediocreDominic,Mar 2026
MCO - SMF
Entertainment
7.5
Overall
8.0
Crew
8.6
Comfort
8.0
Boarding
8.1
Food
7.0
Reviews
1 / 20
2.0
MediocreDominic,Mar 2026
MCO - SMF
Entertainment
7.5
Overall
8.0
Crew
8.6
Comfort
8.0
Boarding
8.1
Food
7.0
Reviews
1 / 20
2.0
MediocreDominic,Mar 2026
MCO - SMF
Entertainment
7.5
Overall
8.0
Crew
8.6
Comfort
8.0
Boarding
8.1
Food
7.0
Reviews
1 / 20
2.0
MediocreDominic,Mar 2026
MCO - SMF
Entertainment
7.5
Overall
8.0
Crew
8.6
Comfort
8.0
Boarding
8.1
Food
7.0
Reviews
1 / 20
2.0
MediocreDominic,Mar 2026
MCO - SMF
Entertainment
7.5
Overall
8.0
Crew
8.6
Comfort
8.0
Boarding
8.1
Food
7.0
Reviews
1 / 20
2.0
MediocreDominic,Mar 2026
MCO - SMF
Related info for your journey
Find useful and relevant information for your journey from LaGuardia to Missouri. Access travel guides, tips, and recommendations to enhance your travel experience. Get information about local attractions, weather, transportation options, and more.
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Alternative routes for LaGuardia to Missouri
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Complete your trip
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Find flights from LaGuardia to Missouri, based on your preferred cabin class, be it economy, premium economy, business, or first class.
LaGuardia and Missouri flights
Browse other LaGuardia and Missouri flight options. Last updated on April 10, 2026.
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Check out other popular destinations found by fellow travelers in 2026
LaGuardia to Missouri flights
Consider these flights traveling from LaGuardia to Missouri.
Top 5 airlines flying from LaGuardia to Missouri
Discover the top 5 airlines that operate flights from LaGuardia to Missouri. Compare their services, reliability, and customer satisfaction ratings to choose the airline that best suits your travel preferences and needs. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated April 10, 2026.
| Airline | Cheapest | Average | Flexibility | On-time |
|---|---|---|---|---|
| Cheapest$146 | Average$193 | FlexibilityNo cancel fee | On-time62% | |
| Cheapest$201 | Average$373 | FlexibilityNo cancel fee | On-timeN/A | |
| Cheapest$207 | Average$377 | FlexibilityNo cancel fee | On-time63% | |
| Cheapest$241 | Average$384 | FlexibilityNo cancel fee | On-time71% | |
| Cheapest$364 | Average$587 | FlexibilityNo cancel fee | On-time69% |