$59+ Cheap flights from District of Columbia to Missouri
This is the cheapest one-way flight price found by a Cheapflights user in the last 72 hours by searching for a flight departing on 3/4. Fares are subject to change and may not be available on all flights or dates of travel.
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1. Tell us where you want to go
Enter your travel information like dates, passengers, trip type (one-way or round trip), and preferred cabin class then click “Find deals”2. Select your favorite providers
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Review each provider’s pricing and select the best option for you! Book through your favorite provider’s website for a seamless experience.Cheap flight deals from District of Columbia to Missouri
Cheapest flights from District of Columbia to MissouriExplore the most affordable flight options available from District of Columbia to Missouri. Find the lowest fares from popular airlines and budget airlines, with prices last updated on January 20, 2026.
Explore the most affordable flight options available from District of Columbia to Missouri. Find the lowest fares from popular airlines and budget airlines, with prices last updated on January 20, 2026.
This CheapOair deal was found by Cheapflights users on 1/18. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure CheapOair is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
This Delta deal was found by Cheapflights users on 1/20. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
This Delta deal was found by Cheapflights users on 1/18. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
This Kiwi.com deal was found by Cheapflights users on 1/17. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
This Expedia deal was found by Cheapflights users on 1/18. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Expedia is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
This Expedia deal was found by Cheapflights users on 1/19. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Expedia is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
This Kiwi.com deal was found by Cheapflights users on 1/18. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
This CheapOair deal was found by Cheapflights users on 1/18. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure CheapOair is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
This Kiwi.com deal was found by Cheapflights users on 1/18. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
This Southwest deal was found by Cheapflights users on 1/18. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
This Southwest deal was found by Cheapflights users on 1/19. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
This Kiwi.com deal was found by Cheapflights users on 1/19. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Find flight deals from District of Columbia to Missouri
Keep the following information in mind while searching for District of Columbia to Missouri flight deals. Data was last updated January 20, 2026.
Most accurate provider | eDreams 3 stars |
|---|---|
Most trusted provider | eDreams 3 stars |
Round-trip from | $251 (CheapOair) |
One-way from | $59 (Trip.com) |
Popular in | January |
Cheapest in | August |
Average price | $443 |
Good round-trip deal | $306 or less |
Good one-way deal | $117 or less |
Cheapflights Fare Finder
Use the filters below to find and compare flights from District of Columbia to Missouri that are best for you.
Fly from
Fly to
Route
Depart
Return
Price
Washington, D.C.St. Louis
IAD - STL
IADSTL
Washington, D.C. Dulles Intl
Sat 2/21
12:35 pm-3:56 pm
1 stop4h 21m
Lambert-St Louis
Wed 2/25
7:10 am-2:45 pm
1 stop6h 35m
Washington, D.C.St. Louis
IAD - STL
IADSTL
Washington, D.C. Dulles Intl
Sat 2/14
6:00 am-9:32 am
1 stop4h 32m
Lambert-St Louis
Sat 2/21
5:01 pm-12:21 am
1 stop6h 20m
Washington, D.C.St. Louis
DCA - STL
DCASTL
Washington, D.C. Reagan-National
Wed 2/11
6:00 am-12:33 pm
1 stop7h 33m
Lambert-St Louis
Wed 2/11
5:32 pm-11:10 pm
1 stop4h 38m
Washington, D.C.St. Louis
DCA - STL
DCASTL
Washington, D.C. Reagan-National
Tue 2/10
12:20 pm-4:07 pm
1 stop4h 47m
Lambert-St Louis
Wed 2/18
6:30 am-12:54 pm
1 stop5h 24m
Washington, D.C.St. Louis
DCA - STL
DCASTL
Washington, D.C. Reagan-National
Tue 3/24
2:00 pm-9:49 am
1 stop20h 49m
Lambert-St Louis
Fri 3/27
8:12 pm-1:02 pm
1 stop15h 50m
Washington, D.C.St. Louis
IAD - STL
IADSTL
Washington, D.C. Dulles Intl
Wed 3/4
8:40 am-10:13 am
Nonstop2h 33m
Lambert-St Louis
Wed 3/25
8:30 am-11:42 am
Nonstop2h 12m
Washington, D.C.Columbia
DCA - COU
DCACOU
Washington, D.C. Reagan-National
Thu 2/5
6:30 am-10:42 am
1 stop5h 12m
Columbia Regional
Wed 2/11
11:17 am-7:13 pm
1 stop6h 56m
Washington, D.C.Columbia
DCA - COU
DCACOU
Washington, D.C. Reagan-National
Thu 2/5
6:30 am-10:42 am
1 stop5h 12m
Columbia Regional
Tue 2/10
3:10 pm-10:37 pm
1 stop6h 27m
Washington, D.C.St. Louis
DCA - STL
DCASTL
Washington, D.C. Reagan-National
Sat 2/21
3:40 pm-11:35 pm
2 stops8h 55m
Lambert-St Louis
Wed 2/25
10:15 am-6:00 pm
2 stops6h 45m
Washington, D.C.Columbia
IAD - COU
IADCOU
Washington, D.C. Dulles Intl
Wed 2/4
5:17 pm-9:37 pm
1 stop5h 20m
Columbia Regional
Sat 2/7
11:17 am-5:35 pm
1 stop5h 18m
Best time to book a flight from District of Columbia to Missouri
Have a flexible travel schedule? Discover the best time to fly to Missouri from District of Columbia with our price prediction graph.
Cheapflights Insights
Everything you need to know about your flight from District of Columbia to Missouri
What is the cheapest month to book a flight from District of Columbia to Missouri?
Currently, September is the cheapest month in which you can book a flight from District of Columbia to Missouri (average of $109). Flying from District of Columbia to Missouri in November is currently the most expensive (average of $192). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.
What is the cheapest time of day to fly from DC to MO?
Find hourly flight availability from District of Columbia to Missouri. Discover flight options and departure times throughout the day, allowing you to choose a departure time that suits your schedule. Data last updated January 20, 2026.
When flying from District of Columbia to Missouri, the time of day you fly usually plays a role in the price. Save by searching for a flight in the evening, which can drop the price by up to 10% versus a flight in the afternoon.
What is the cheapest day to fly from District of Columbia to Missouri?
Use this chart to determine the cheapest time to fly round-trip from District of Columbia to Missouri. Price data was last updated on January 17, 2026.
Travelers seeking maximum savings on their District of Columbia to Missouri flight should consider departing on Friday evenings when fares are most often at their lowest. Sunday afternoons flights should be avoided if possible as fares are typically the most expensive at this time.
Weekly flight availability from District of Columbia to Missouri
Explore weekly flight availability from District of Columbia to Missouri. Discover flights operating on different days of the week, giving you the flexibility to choose a travel day that best fits your plans. Compare info to find the most convenient option for your journey. Data last updated January 20, 2026.
The most flights from USDC to USMO are scheduled on a Monday (8 on average). You will have fewer flight options on Monday, which is when the least amount of flights are scheduled (8 on average).
Reviews of airlines servicing Missouri
Get insights into the airlines that provide service to Missouri. Read reviews, discover amenities, and learn about the overall travel experience offered by airlines. Use this information to make informed decisions when choosing an airline for your flight to Missouri. Reviews last updated January 20, 2026.
Peruse reviews from past customers who have flown with Southwest, Delta, and United Airlines from District of Columbia to Missouri to help guide your decision. Reviews also offer insight into each airline's entertainment options, comfort, food, crew/service, and boarding process.
Boarding
Crew
Food
Overall
Comfort
Entertainment
Reviews
Thomas,Dec 2025
SEA - DEN
Boarding
Crew
Food
Overall
Comfort
Entertainment
Reviews
Thomas,Dec 2025
SEA - DEN
Boarding
Crew
Food
Overall
Comfort
Entertainment
Reviews
Thomas,Dec 2025
SEA - DEN
Boarding
Crew
Food
Overall
Comfort
Entertainment
Reviews
Thomas,Dec 2025
SEA - DEN
Boarding
Crew
Food
Overall
Comfort
Entertainment
Reviews
Thomas,Dec 2025
SEA - DEN
Boarding
Crew
Food
Overall
Comfort
Entertainment
Reviews
Thomas,Dec 2025
SEA - DEN
Related info for your journey
Find useful and relevant information for your journey from District of Columbia to Missouri. Access travel guides, tips, and recommendations to enhance your travel experience. Get information about local attractions, weather, transportation options, and more.
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Alternative routes for District of Columbia to Missouri
See prices for flight routes from nearby airports that may be better suited for you.
Top 6 airlines flying from District of Columbia to Missouri
Discover the top 6 airlines that operate flights from District of Columbia to Missouri. Compare their services, reliability, and customer satisfaction ratings to choose the airline that best suits your travel preferences and needs. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated January 20, 2026.
| Airline | Cheapest | Average | Flexibility | On-time |
|---|---|---|---|---|
| Cheapest$78 | Average$200 | FlexibilityNo cancel fee | On-time62% | |
| Cheapest$111 | Average$231 | FlexibilityNo cancel fee | On-time65% | |
| Cheapest$124 | Average$337 | FlexibilityNo cancel fee | On-timeN/A | |
| Cheapest$167 | Average$379 | FlexibilityNo cancel fee | On-time71% | |
| Cheapest$187 | Average$371 | FlexibilityNo cancel fee | On-time63% | |
| Cheapest$233 | Average$430 | FlexibilityNo cancel fee | On-time69% |