$49+ Cheap flights from Chicago (CHI) to Missouri
This is the cheapest one-way flight price found by a Cheapflights user in the last 72 hours by searching for a flight departing on 4/28. Fares are subject to change and may not be available on all flights or dates of travel.
CHI — STL
Mar 24 — Mar 311
1 adult, Economy
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Find cheap flights from Chicago to Missouri with Cheapflights
1. Tell us where you want to go
Enter your travel information like dates, passengers, trip type (one-way or round trip), and preferred cabin class then click “Find deals”2. Select your favorite providers
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Cheapest flights from Chicago to MissouriExplore the most affordable flight options available from Chicago to Missouri. Find the lowest fares from popular airlines and budget airlines, with prices last updated on February 22, 2026.
Explore the most affordable flight options available from Chicago to Missouri. Find the lowest fares from popular airlines and budget airlines, with prices last updated on February 22, 2026.
This Mytrip deal was found by Cheapflights users on 2/19. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Mytrip is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 3/611:50 am
ORD
- CGI
Nonstop1h 40m
Contour
Tue 3/109:25 am
CGI
- ORD
Nonstop1h 45m
Contour
Deal found 2/19![Contour logo]()
$125
This Contour deal was found by Cheapflights users on 2/20. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Contour is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 3/711:50 am
ORD
- CGI
Nonstop1h 40m
Contour
Wed 3/119:25 am
CGI
- ORD
Nonstop1h 45m
Contour
Deal found 2/20![Contour logo]()
$139
This CheapOair deal was found by Cheapflights users on 2/19. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure CheapOair is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 3/911:50 am
ORD
- CGI
Nonstop1h 40m
Contour
Thu 3/199:25 am
CGI
- ORD
Nonstop1h 45m
Contour
Deal found 2/19![Contour logo]()
$140
This Contour deal was found by Cheapflights users on 2/19. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Contour is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 7/1612:10 pm
ORD
- CGI
Nonstop1h 40m
Contour
Sat 8/81:30 pm
CGI
- ORD
Nonstop1h 45m
Contour
Deal found 2/19![Contour logo]()
$158
This Mytrip deal was found by Cheapflights users on 2/19. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Mytrip is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 6/412:10 pm
ORD
- CGI
Nonstop1h 40m
Contour
Fri 6/59:45 am
CGI
- ORD
Nonstop1h 45m
Contour
Deal found 2/19![Contour logo]()
$166
This American Airlines deal was found by Cheapflights users on 2/19. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 4/308:12 am
ORD
- COU
Nonstop1h 31m
American Airlines
Sun 5/36:00 am
COU
- ORD
Nonstop1h 43m
American Airlines
Deal found 2/19![American Airlines logo]()
$179
This American Airlines deal was found by Cheapflights users on 2/20. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 4/87:07 pm
ORD
- SGF
Nonstop1h 55m
American Airlines
Mon 4/136:05 pm
SGF
- ORD
Nonstop1h 59m
American Airlines
Deal found 2/20![American Airlines logo]()
$189
This United Airlines deal was found by Cheapflights users on 2/21. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 7/108:08 pm
ORD
- COU
Nonstop1h 51m
United Airlines
Sun 7/128:00 am
COU
- ORD
Nonstop1h 40m
United Airlines
Deal found 2/21![United Airlines logo]()
$193
This United Airlines deal was found by Cheapflights users on 2/20. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 3/1212:40 pm
ORD
- COU
Nonstop1h 26m
United Airlines
Sun 3/158:00 am
COU
- ORD
Nonstop1h 30m
United Airlines
Deal found 2/20![United Airlines logo]()
$194
This United Airlines deal was found by Cheapflights users on 2/19. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 4/298:55 am
ORD
- SGF
Nonstop1h 53m
United Airlines
Thu 5/76:25 pm
SGF
- ORD
Nonstop1h 43m
United Airlines
Deal found 2/19![United Airlines logo]()
$202
This Delta deal was found by Cheapflights users on 2/19. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 4/259:48 am
ORD
- SGF
1 stop5h 26m
Delta
Mon 4/276:55 pm
SGF
- ORD
1 stop5h 04m
Delta
Deal found 2/19![Delta logo]()
$209
This Delta deal was found by Cheapflights users on 2/19. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 4/256:00 am
MDW
- SGF
1 stop5h 01m
Delta
Tue 4/283:59 pm
SGF
- MDW
1 stop6h 29m
Delta
Deal found 2/19![Delta logo]()
$209
Best flights from Chicago to MissouriDiscover carefully curated flight deals from Chicago to Missouri that have cost, travel time, and layovers in mind to ensure you get the best travel experience. Data last updated February 22, 2026.
Discover carefully curated flight deals from Chicago to Missouri that have cost, travel time, and layovers in mind to ensure you get the best travel experience. Data last updated February 22, 2026.
This Mytrip deal was found by Cheapflights users on 2/19. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Mytrip is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 3/611:50 am
ORD
- CGI
Nonstop1h 40m
Contour
Tue 3/109:25 am
CGI
- ORD
Nonstop1h 45m
Contour
Deal found 2/19![Contour logo]()
$125
This American Airlines deal was found by Cheapflights users on 2/18. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 5/28:12 am
ORD
- COU
Nonstop1h 31m
American Airlines
Sun 6/216:27 pm
COU
- ORD
Nonstop1h 47m
American Airlines
Deal found 2/18![American Airlines logo]()
$179
This United Airlines deal was found by Cheapflights users on 2/19. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 4/258:55 am
ORD
- SGF
Nonstop1h 53m
United Airlines
Tue 4/286:30 pm
SGF
- ORD
Nonstop1h 48m
United Airlines
Deal found 2/19![United Airlines logo]()
$189
This Delta deal was found by Cheapflights users on 2/19. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 4/256:00 am
MDW
- SGF
1 stop5h 01m
Delta
Tue 4/283:59 pm
SGF
- MDW
1 stop6h 29m
Delta
Deal found 2/19![Delta logo]()
$209
This Southwest deal was found by Cheapflights users on 2/19. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 3/177:35 am
MDW
- MCI
Nonstop1h 30m
Southwest
Sat 3/216:00 pm
MCI
- MDW
1 stop6h 05m
Southwest
Deal found 2/19![Southwest logo]()
$224
This Expedia deal was found by Cheapflights users on 2/19. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Expedia is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 3/134:18 pm
ORD
- STL
1 stop7h 01m
Frontier
Mon 3/164:51 pm
STL
- ORD
1 stop6h 47m
Frontier
Deal found 2/19![Frontier logo]()
$240
This Contour deal was found by Cheapflights users on 2/21. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Contour is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 4/112:10 pm
ORD
- CGI
Nonstop1h 40m
Contour
Thu 4/99:45 am
CGI
- ORD
Nonstop1h 45m
Contour
Deal found 2/21![Contour logo]()
$139
This Contour deal was found by Cheapflights users on 2/20. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Contour is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 3/711:50 am
ORD
- CGI
Nonstop1h 40m
Contour
Wed 3/119:25 am
CGI
- ORD
Nonstop1h 45m
Contour
Deal found 2/20![Contour logo]()
$139
This Contour deal was found by Cheapflights users on 2/22. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Contour is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 3/911:50 am
ORD
- CGI
Nonstop1h 40m
Contour
Thu 3/199:25 am
CGI
- ORD
Nonstop1h 45m
Contour
Deal found 2/22![Contour logo]()
$139
This American Airlines deal was found by Cheapflights users on 2/18. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 4/46:50 pm
ORD
- COU
Nonstop1h 29m
American Airlines
Sat 4/114:28 pm
COU
- ORD
Nonstop1h 42m
American Airlines
Deal found 2/18![American Airlines logo]()
$179
This Kiwi.com deal was found by Cheapflights users on 2/19. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 3/65:15 am
ORD
- CGI
1 stop15h 20m
Multiple Airlines
Tue 3/109:25 am
CGI
- ORD
Nonstop1h 45m
Multiple Airlines
Deal found 2/19![Multiple Airlines logo]()
$365
This United Airlines deal was found by Cheapflights users on 2/22. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 3/137:58 pm
ORD
- COU
Nonstop1h 35m
United Airlines
Sun 3/158:00 am
COU
- ORD
Nonstop1h 30m
United Airlines
Deal found 2/22![United Airlines logo]()
$194
This American Airlines deal was found by Cheapflights users on 2/18. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 4/88:43 pm
ORD
- SGF
Nonstop1h 55m
American Airlines
Mon 4/135:19 am
SGF
- ORD
Nonstop1h 48m
American Airlines
Deal found 2/18![American Airlines logo]()
$189
This Contour deal was found by Cheapflights users on 2/19. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Contour is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 7/1612:10 pm
ORD
- CGI
Nonstop1h 40m
Contour
Sat 8/81:30 pm
CGI
- ORD
Nonstop1h 45m
Contour
Deal found 2/19![Contour logo]()
$158
This Delta deal was found by Cheapflights users on 2/19. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 4/229:50 am
ORD
- SGF
1 stop5h 24m
Delta
Mon 4/276:55 pm
SGF
- ORD
1 stop5h 04m
Delta
Deal found 2/19![Delta logo]()
$224
This Southwest deal was found by Cheapflights users on 2/20. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 4/105:55 pm
MDW
- MCI
1 stop5h 40m
Southwest
Sun 4/128:35 am
MCI
- MDW
Nonstop1h 25m
Southwest
Deal found 2/20![Southwest logo]()
$226
This American Airlines deal was found by Cheapflights users on 2/18. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 4/248:43 pm
ORD
- SGF
Nonstop1h 55m
American Airlines
Sun 4/267:34 am
SGF
- ORD
Nonstop1h 56m
American Airlines
Deal found 2/18![American Airlines logo]()
$189
This United Airlines deal was found by Cheapflights users on 2/20. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 3/63:35 pm
ORD
- SGF
Nonstop1h 58m
United Airlines
Mon 3/96:08 pm
SGF
- ORD
Nonstop1h 58m
United Airlines
Deal found 2/20![United Airlines logo]()
$219
This Mytrip deal was found by Cheapflights users on 2/19. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Mytrip is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 6/412:10 pm
ORD
- CGI
Nonstop1h 40m
Contour
Fri 6/59:45 am
CGI
- ORD
Nonstop1h 45m
Contour
Deal found 2/19![Contour logo]()
$166
This Delta deal was found by Cheapflights users on 2/19. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 5/68:15 am
ORD
- SGF
1 stop6h 59m
Delta
Mon 5/116:51 pm
SGF
- ORD
1 stop5h 08m
Delta
Deal found 2/19![Delta logo]()
$224
This Southwest deal was found by Cheapflights users on 2/18. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 4/212:00 pm
ORD
- MCI
1 stop7h 05m
Southwest
Tue 4/287:25 am
MCI
- ORD
2 stops11h 25m
Southwest
Deal found 2/18![Southwest logo]()
$228
This United Airlines deal was found by Cheapflights users on 2/19. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 3/2412:40 pm
ORD
- MCI
Nonstop1h 40m
United Airlines
Fri 3/273:22 pm
MCI
- ORD
Nonstop1h 43m
United Airlines
Deal found 2/19![United Airlines logo]()
$221
This Delta deal was found by Cheapflights users on 2/19. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 4/158:15 am
ORD
- SGF
1 stop6h 59m
Delta
Mon 4/206:55 pm
SGF
- ORD
1 stop5h 04m
Delta
Deal found 2/19![Delta logo]()
$224
This American Airlines deal was found by Cheapflights users on 2/18. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 3/56:50 pm
ORD
- COU
Nonstop1h 29m
American Airlines
Sat 3/75:41 pm
COU
- ORD
Nonstop1h 30m
American Airlines
Deal found 2/18![American Airlines logo]()
$209
This CheapOair deal was found by Cheapflights users on 2/18. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure CheapOair is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 3/1910:53 am
ORD
- STL
1 stop22h 56m
Frontier
Thu 3/2611:21 am
STL
- ORD
1 stop11h 18m
Frontier
Deal found 2/18![Frontier logo]()
$281
This Southwest deal was found by Cheapflights users on 2/19. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 5/912:15 pm
ORD
- MCI
1 stop8h 25m
Southwest
Tue 5/125:30 am
MCI
- ORD
1 stop5h 40m
Southwest
Deal found 2/19![Southwest logo]()
$243
This Delta deal was found by Cheapflights users on 2/19. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 4/1510:41 am
MDW
- SGF
1 stop4h 33m
Delta
Mon 4/203:59 pm
SGF
- MDW
1 stop6h 29m
Delta
Deal found 2/19![Delta logo]()
$224
This American Airlines deal was found by Cheapflights users on 2/18. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 3/68:10 am
ORD
- COU
Nonstop1h 28m
American Airlines
Sun 3/86:00 am
COU
- ORD
Nonstop1h 36m
American Airlines
Deal found 2/18![American Airlines logo]()
$209
This United Airlines deal was found by Cheapflights users on 2/18. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 3/208:12 pm
ORD
- STL
Nonstop1h 30m
United Airlines
Sun 3/225:00 am
STL
- ORD
Nonstop1h 30m
United Airlines
Deal found 2/18![United Airlines logo]()
$242
This Southwest deal was found by Cheapflights users on 2/20. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 4/269:45 pm
MDW
- STL
Nonstop1h 15m
Southwest
Tue 4/284:35 pm
STL
- MDW
1 stop5h 10m
Southwest
Deal found 2/20![Southwest logo]()
$245
Last-minute flights from Chicago to MissouriDiscover last-minute flight deals from Chicago to Missouri. Data last updated February 22, 2026 and is based on user searches.
Discover last-minute flight deals from Chicago to Missouri. Data last updated February 22, 2026 and is based on user searches.
This Mytrip deal was found by Cheapflights users on 2/19. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Mytrip is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 3/611:50 am
ORD
- CGI
Nonstop1h 40m
Contour
Tue 3/109:25 am
CGI
- ORD
Nonstop1h 45m
Contour
Deal found 2/19![Contour logo]()
$125
This American Airlines deal was found by Cheapflights users on 2/19. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 3/68:10 am
ORD
- COU
Nonstop1h 28m
American Airlines
Sun 3/86:00 am
COU
- ORD
Nonstop1h 36m
American Airlines
Deal found 2/19![American Airlines logo]()
$209
This United Airlines deal was found by Cheapflights users on 2/20. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 3/63:35 pm
ORD
- SGF
Nonstop1h 58m
United Airlines
Mon 3/96:08 pm
SGF
- ORD
Nonstop1h 58m
United Airlines
Deal found 2/20![United Airlines logo]()
$219
This Contour deal was found by Cheapflights users on 2/20. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Contour is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 3/711:50 am
ORD
- CGI
Nonstop1h 40m
Contour
Wed 3/119:25 am
CGI
- ORD
Nonstop1h 45m
Contour
Deal found 2/20![Contour logo]()
$139
This CheapOair deal was found by Cheapflights users on 2/19. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure CheapOair is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 3/911:50 am
ORD
- CGI
Nonstop1h 40m
Contour
Thu 3/199:25 am
CGI
- ORD
Nonstop1h 45m
Contour
Deal found 2/19![Contour logo]()
$140
This United Airlines deal was found by Cheapflights users on 2/20. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 3/1212:40 pm
ORD
- COU
Nonstop1h 26m
United Airlines
Sun 3/158:00 am
COU
- ORD
Nonstop1h 30m
United Airlines
Deal found 2/20![United Airlines logo]()
$194
This American Airlines deal was found by Cheapflights users on 2/19. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 3/136:50 pm
ORD
- COU
Nonstop1h 29m
American Airlines
Sun 3/156:30 pm
COU
- ORD
Nonstop1h 35m
American Airlines
Deal found 2/19![American Airlines logo]()
$179
This Southwest deal was found by Cheapflights users on 2/19. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 3/177:35 am
MDW
- MCI
Nonstop1h 30m
Southwest
Sat 3/216:00 pm
MCI
- MDW
1 stop6h 05m
Southwest
Deal found 2/19![Southwest logo]()
$224
This American Airlines deal was found by Cheapflights users on 2/19. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 3/198:03 am
ORD
- SGF
Nonstop1h 50m
American Airlines
Mon 3/236:00 pm
SGF
- ORD
Nonstop1h 49m
American Airlines
Deal found 2/19![American Airlines logo]()
$189
This United Airlines deal was found by Cheapflights users on 2/18. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 3/2412:40 pm
ORD
- MCI
Nonstop1h 40m
United Airlines
Fri 3/279:15 am
MCI
- ORD
Nonstop1h 41m
United Airlines
Deal found 2/18![United Airlines logo]()
$221
This American Airlines deal was found by Cheapflights users on 2/18. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 3/259:13 pm
ORD
- COU
1 stop19h 54m
American Airlines
Thu 3/266:30 pm
COU
- ORD
Nonstop1h 35m
American Airlines
Deal found 2/18![American Airlines logo]()
$216
This American Airlines deal was found by Cheapflights users on 2/22. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 3/265:00 pm
ORD
- MCI
1 stop6h 59m
American Airlines
Fri 3/275:00 am
MCI
- ORD
Nonstop1h 41m
American Airlines
Deal found 2/22![American Airlines logo]()
$224
One-way flights from Chicago to MissouriSearch for one-way flight options from Chicago to Missouri. Find affordable one-way fares based on user searches. Data last updated February 22, 2026.
Search for one-way flight options from Chicago to Missouri. Find affordable one-way fares based on user searches. Data last updated February 22, 2026.
This Southwest deal was found by Cheapflights users on 2/20. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 4/228:15 am
MDW
- STL
Nonstop1h 15m
Southwest
Deal found 2/20![Southwest logo]()
$49
This United Airlines deal was found by Cheapflights users on 2/20. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 3/317:40 pm
ORD
- STL
Nonstop1h 28m
United Airlines
Deal found 2/20![United Airlines logo]()
$49
This United Airlines deal was found by Cheapflights users on 2/22. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 3/288:15 pm
ORD
- MCI
Nonstop1h 44m
United Airlines
Deal found 2/22![United Airlines logo]()
$56
This Southwest deal was found by Cheapflights users on 2/19. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 4/202:10 pm
MDW
- STL
Nonstop1h 15m
Southwest
Deal found 2/19![Southwest logo]()
$59
This United Airlines deal was found by Cheapflights users on 2/20. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 3/288:12 pm
ORD
- STL
Nonstop1h 30m
United Airlines
Deal found 2/20![United Airlines logo]()
$59
This Booking.com deal was found by Cheapflights users on 2/19. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Booking.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 3/1711:50 am
ORD
- CGI
Nonstop1h 40m
Contour
Deal found 2/19![Contour logo]()
$61
This Southwest deal was found by Cheapflights users on 2/19. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 4/811:35 am
MDW
- STL
2 stops6h 20m
Southwest
Deal found 2/19![Southwest logo]()
$64
This Southwest deal was found by Cheapflights users on 2/20. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 5/202:40 pm
ORD
- STL
1 stop7h 20m
Southwest
Deal found 2/20![Southwest logo]()
$64
This United Airlines deal was found by Cheapflights users on 2/20. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 3/1810:56 am
ORD
- STL
Nonstop1h 31m
United Airlines
Deal found 2/20![United Airlines logo]()
$66
This Southwest deal was found by Cheapflights users on 2/19. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 5/163:05 pm
MDW
- STL
1 stop5h 15m
Southwest
Deal found 2/19![Southwest logo]()
$69
This Southwest deal was found by Cheapflights users on 2/22. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 5/22:05 pm
ORD
- STL
1 stop6h 15m
Southwest
Deal found 2/22![Southwest logo]()
$69
This Booking.com deal was found by Cheapflights users on 2/20. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Booking.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 7/912:10 pm
ORD
- CGI
Nonstop1h 40m
Contour
Deal found 2/20![Contour logo]()
$71
Find flight deals from Chicago to Missouri
Keep the following information in mind while searching for Chicago to Missouri flight deals. Data was last updated February 22, 2026.
Most accurate provider | FlightHub 3 stars |
|---|---|
Most trusted provider | FlightHub 3 stars |
Round-trip from | $125 (Mytrip) |
One-way from | $49 (Southwest) |
Popular in | January |
Cheapest in | December |
Average price | $529 |
Good round-trip deal | $118 or less |
Good one-way deal | $65 or less |
Cheapflights Fare Finder
Customize your flight search to find flights from Chicago to Missouri that fit within your specific budget. Explore options based on user searches and filter the results based on your desired price range. Find flights that match your budget for a cost-effective journey. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated February 22, 2026.
Use the filters below to find and compare flights from Chicago to Missouri that are best for you.
Fly from
Chicago
Fly to
Missouri
Route
Depart
Return
Price
ChicagoCape Girardeau
ORD - CGI
ORDCGI
Chicago O'Hare Intl
Fri 3/6
11:50 am-1:30 pm
Nonstop1h 40m
Cape Girardeau
Tue 3/10
9:25 am-11:10 am
Nonstop1h 45m
$125
ChicagoCape Girardeau
ORD - CGI
ORDCGI
Chicago O'Hare Intl
Wed 4/1
12:10 pm-1:50 pm
Nonstop1h 40m
Cape Girardeau
Thu 4/9
9:45 am-11:30 am
Nonstop1h 45m
$139
ChicagoCape Girardeau
ORD - CGI
ORDCGI
Chicago O'Hare Intl
Sat 3/7
11:50 am-1:30 pm
Nonstop1h 40m
Cape Girardeau
Wed 3/11
9:25 am-11:10 am
Nonstop1h 45m
$139
ChicagoCape Girardeau
ORD - CGI
ORDCGI
Chicago O'Hare Intl
Mon 3/9
11:50 am-1:30 pm
Nonstop1h 40m
Cape Girardeau
Thu 3/19
9:25 am-11:10 am
Nonstop1h 45m
$139
ChicagoCape Girardeau
ORD - CGI
ORDCGI
Chicago O'Hare Intl
Thu 7/16
12:10 pm-1:50 pm
Nonstop1h 40m
Cape Girardeau
Sat 8/8
1:30 pm-3:15 pm
Nonstop1h 45m
$158
ChicagoCape Girardeau
ORD - CGI
ORDCGI
Chicago O'Hare Intl
Thu 6/4
12:10 pm-1:50 pm
Nonstop1h 40m
Cape Girardeau
Fri 6/5
9:45 am-11:30 am
Nonstop1h 45m
$166
ChicagoColumbia
ORD - COU
ORDCOU
Chicago O'Hare Intl
Sat 5/2
8:12 am-9:43 am
Nonstop1h 31m
Columbia Regional
Sun 6/21
6:27 pm-8:14 pm
Nonstop1h 47m
$179
ChicagoColumbia
ORD - COU
ORDCOU
Chicago O'Hare Intl
Sat 4/4
6:50 pm-8:19 pm
Nonstop1h 29m
Columbia Regional
Sat 4/11
4:28 pm-6:10 pm
Nonstop1h 42m
$179
ChicagoSpringfield
ORD - SGF
ORDSGF
Chicago O'Hare Intl
Sat 4/25
8:55 am-10:48 am
Nonstop1h 53m
Springfield-Branson
Tue 4/28
6:30 pm-8:18 pm
Nonstop1h 48m
$189
ChicagoSpringfield
ORD - SGF
ORDSGF
Chicago O'Hare Intl
Wed 4/8
8:43 pm-10:38 pm
Nonstop1h 55m
Springfield-Branson
Mon 4/13
5:19 am-7:07 am
Nonstop1h 48m
$189
Showing 1-10 of 60 results
Best time to book a flight from Chicago to Missouri
Have a flexible travel schedule? Discover the best time to fly to Missouri from Chicago with our price prediction graph.
ORD-CGI
ORD-COU
ORD-SGF
ORD-MCI
MDW-MCI
Estimated round-trip price
Rates are based on past data. Find the cheapest month and day to book your flight based on your travel requirements, then search for cheap deals.
Cheapflights Insights
Everything you need to know about your flight from Chicago to Missouri
CHI-USMO
ORD-CGI
ORD-COU
ORD-SGF
ORD-MCI
What is the cheapest month to book a flight from Chicago to Missouri?
Currently, August is the cheapest month in which you can book a flight from Chicago to Missouri (average of $77). Flying from Chicago to Missouri in June is currently the most expensive (average of $143). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.
What is the cheapest time of day to fly from CHI to MO?
Find hourly flight availability from Chicago to Missouri. Discover flight options and departure times throughout the day, allowing you to choose a departure time that suits your schedule. Data last updated February 22, 2026.
It’s optimal to fly from Chicago to Missouri in the morning. By choosing this option you can save up to 13% on the cost of your flight, compared to a flight in the evening.
What is the cheapest day to fly from Chicago to Missouri?
Use this chart to determine the cheapest time to fly round-trip from Chicago to Missouri. Price data was last updated on February 21, 2026.
Travelers seeking maximum savings on their Chicago to Missouri flight should consider departing on Friday afternoons when fares are most often at their lowest. Saturday evenings flights should be avoided if possible as fares are typically the most expensive at this time.
Weekly flight availability from Chicago to Missouri
Explore weekly flight availability from Chicago to Missouri. Discover flights operating on different days of the week, giving you the flexibility to choose a travel day that best fits your plans. Compare info to find the most convenient option for your journey. Data last updated February 22, 2026.
The most flights from CHI to USMO are scheduled on a Friday (63 on average). You will have fewer flight options on Tuesday, which is when the least amount of flights are scheduled (33 on average).
Reviews of airlines servicing Missouri
Get insights into the airlines that provide service to Missouri. Read reviews, discover amenities, and learn about the overall travel experience offered by airlines. Use this information to make informed decisions when choosing an airline for your flight to Missouri. Reviews last updated February 22, 2026.
Get a feel of what it's like to fly with Southwest, Contour, and United Airlines from Chicago to Missouri by reading reviews from past customers. You can also see how each airline compares in terms of entertainment options, comfort, food, crew/service, and boarding process.
Food
7.0
Crew
8.6
Boarding
8.1
Entertainment
7.5
Comfort
8.0
Overall
8.0
Reviews
1 / 20
2.0
MediocreThomas,Dec 2025
SEA - DEN
Food
7.0
Crew
8.6
Boarding
8.1
Entertainment
7.5
Comfort
8.0
Overall
8.0
Reviews
1 / 20
2.0
MediocreThomas,Dec 2025
SEA - DEN
Food
7.0
Crew
8.6
Boarding
8.1
Entertainment
7.5
Comfort
8.0
Overall
8.0
Reviews
1 / 20
2.0
MediocreThomas,Dec 2025
SEA - DEN
Food
7.0
Crew
8.6
Boarding
8.1
Entertainment
7.5
Comfort
8.0
Overall
8.0
Reviews
1 / 20
2.0
MediocreThomas,Dec 2025
SEA - DEN
Food
7.0
Crew
8.6
Boarding
8.1
Entertainment
7.5
Comfort
8.0
Overall
8.0
Reviews
1 / 20
2.0
MediocreThomas,Dec 2025
SEA - DEN
Food
7.0
Crew
8.6
Boarding
8.1
Entertainment
7.5
Comfort
8.0
Overall
8.0
Reviews
1 / 20
2.0
MediocreThomas,Dec 2025
SEA - DEN
Related info for your journey
Find useful and relevant information for your journey from Chicago to Missouri. Access travel guides, tips, and recommendations to enhance your travel experience. Get information about local attractions, weather, transportation options, and more.
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Alternative routes for Chicago to Missouri
See prices for flight routes from nearby airports that may be better suited for you.
Complete your trip
Complete your trip to Missouri by adding a car rental and/or hotel reservation to your travel itinerary.
Search flights from Chicago to Missouri by cabin class
Find flights from Chicago to Missouri, based on your preferred cabin class, be it economy, premium economy, business, or first class.
Chicago and Missouri flights
Browse other Chicago and Missouri flight options. Last updated on February 22, 2026.
Popular flight searches
Check out other popular destinations found by fellow travelers in 2026
Chicago to Missouri flights
Consider these flights traveling from Chicago to Missouri.
Top 5 airlines flying from Chicago to Missouri
Discover the top 5 airlines that operate flights from Chicago to Missouri. Compare their services, reliability, and customer satisfaction ratings to choose the airline that best suits your travel preferences and needs. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated February 22, 2026.
| Airline | Cheapest | Average | Flexibility | On-time |
|---|---|---|---|---|
| Cheapest$77 | Average$349 | FlexibilityNo cancel fee | On-time63% | |
| Cheapest$105 | Average$171 | FlexibilityNo cancel fee | On-timeN/A | |
| Cheapest$121 | Average$310 | FlexibilityNo cancel fee | On-time71% | |
| Cheapest$151 | Average$346 | FlexibilityNo cancel fee | On-time69% | |
| Cheapest$156 | Average$215 | FlexibilityNo cancel fee | On-timeN/A |