$59+ Cheap flights from Chicago (CHI) to Missouri
This is the cheapest round-trip flight price found by a Cheapflights user in the last 72 hours by searching for a flight departing on 9/30. Fares are subject to change and may not be available on all flights or dates of travel.
CHI — STL
Oct 5 — Oct 121
Round-trip
1 adult, Economy
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Find cheap flights from Chicago to Missouri with Cheapflights
1. Tell us where you want to go
Enter your travel information like dates, passengers, trip type (one-way or round trip), and preferred cabin class then click “Find deals”2. Select your favorite providers
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Cheapest flights from Chicago to MissouriExplore the most affordable flight options available from Chicago to Missouri. Find the lowest fares from popular airlines and budget airlines, with prices last updated on September 5, 2026.
Explore the most affordable flight options available from Chicago to Missouri. Find the lowest fares from popular airlines and budget airlines, with prices last updated on September 5, 2026.
This Southwest deal was found by Cheapflights users on 9/1. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 10/167:50 am -
Nonstop1h 10m
Fri 10/236:10 pm -
Nonstop1h 05m
Deal found 9/1![Southwest logo]()
$151
This Frontier deal was found by Cheapflights users on 9/1. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Frontier is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 9/266:30 am -
1 stop12h 47m
Mon 9/2812:17 pm -
1 stop17h 21m
Deal found 9/1![Frontier logo]()
$151
This American Airlines deal was found by Cheapflights users on 9/1. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 10/1611:00 pm -
Nonstop1h 19m
Fri 10/2311:31 am -
Nonstop1h 28m
Deal found 9/1![American Airlines logo]()
$153
This Southwest deal was found by Cheapflights users on 8/31. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 9/245:55 am -
1 stop4h 15m
Fri 9/255:40 pm -
1 stop4h 45m
Deal found 8/31![Southwest logo]()
$154
This Delta deal was found by Cheapflights users on 9/1. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 9/291:19 pm -
1 stop3h 51m
Thu 10/16:40 am -
1 stop5h 59m
Deal found 9/1![Delta logo]()
$157
This Delta deal was found by Cheapflights users on 9/2. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 10/1011:09 am -
1 stop4h 28m
Mon 10/126:47 am -
1 stop6h 12m
Deal found 9/2![Delta logo]()
$157
This CheapOair deal was found by Cheapflights users on 9/1. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure CheapOair is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 9/2411:15 am -
1 stop6h 39m
Tue 9/2912:17 pm -
1 stop17h 21m
Deal found 9/1![Frontier logo]()
$160
This Delta deal was found by Cheapflights users on 9/2. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 9/285:50 pm -
1 stop5h 26m
Tue 9/295:47 pm -
1 stop3h 46m
Deal found 9/2![Delta logo]()
$164
This iWofly deal was found by Cheapflights users on 9/1. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure iWofly is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 10/166:20 am -
1 stop10h 38m
Fri 10/238:00 pm -
1 stop28h 24m
Deal found 9/1![Frontier logo]()
$166
This Frontier deal was found by Cheapflights users on 9/1. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Frontier is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 9/2411:15 am -
1 stop6h 39m
Mon 9/2812:17 pm -
1 stop17h 21m
Deal found 9/1![Frontier logo]()
$168
This eDestinos deal was found by Cheapflights users on 9/5. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure eDestinos is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 10/1511:15 am -
Nonstop1h 35m
Wed 10/219:40 am -
Nonstop1h 55m
Deal found 9/5![Contour logo]()
$175
This Kiwi.com deal was found by Cheapflights users on 9/4. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 10/286:16 am -
1 stop11h 24m
Fri 10/306:44 pm -
1 stop23h 03m
Deal found 9/4![Frontier logo]()
$175
Best flights from Chicago to MissouriDiscover carefully curated flight deals from Chicago to Missouri that have cost, travel time, and layovers in mind to ensure you get the best travel experience. Data last updated September 5, 2026.
Discover carefully curated flight deals from Chicago to Missouri that have cost, travel time, and layovers in mind to ensure you get the best travel experience. Data last updated September 5, 2026.
This eDestinos deal was found by Cheapflights users on 9/5. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure eDestinos is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 10/1511:15 am -
Nonstop1h 35m
Wed 10/219:40 am -
Nonstop1h 55m
Deal found 9/5![Contour logo]()
$175
This United Airlines deal was found by Cheapflights users on 9/3. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 10/2710:45 am -
Nonstop1h 25m
Tue 10/276:50 pm -
Nonstop1h 29m
Deal found 9/3![United Airlines logo]()
$194
This Southwest deal was found by Cheapflights users on 9/3. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 9/2912:35 pm -
1 stop4h 10m
Thu 10/110:20 am -
1 stop3h 55m
Deal found 9/3![Southwest logo]()
$208
This Delta deal was found by Cheapflights users on 9/2. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 10/191:25 pm -
1 stop3h 54m
Tue 10/202:38 pm -
1 stop5h 52m
Deal found 9/2![Delta logo]()
$278
This American Airlines deal was found by Cheapflights users on 9/5. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 11/105:29 pm -
Nonstop1h 50m
Tue 11/175:26 pm -
Nonstop1h 59m
Deal found 9/5![American Airlines logo]()
$279
This CheapOair deal was found by Cheapflights users on 9/5. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure CheapOair is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 10/76:30 am -
1 stop13h 07m
Sat 10/108:43 pm -
1 stop27h 41m
Deal found 9/5![Frontier logo]()
$349
This Mytrip deal was found by Cheapflights users on 9/1. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Mytrip is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 9/2411:15 am -
Nonstop1h 35m
Tue 9/299:50 am -
Nonstop1h 55m
Deal found 9/1![Contour logo]()
$186
This Contour deal was found by Cheapflights users on 9/4. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Contour is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 10/3011:15 am -
Nonstop1h 35m
Sat 10/319:40 am -
Nonstop1h 55m
Deal found 9/4![Contour logo]()
$198
This Alaska Airlines deal was found by Cheapflights users on 9/5. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Alaska Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 10/26:00 am -
1 stop17h 59m
Sun 10/46:17 am -
1 stop23h 23m
Deal found 9/5![Alaska Airlines logo]()
$473
This Contour deal was found by Cheapflights users on 8/31. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Contour is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 11/511:15 am -
Nonstop1h 35m
Mon 11/99:40 am -
Nonstop1h 55m
Deal found 8/31![Contour logo]()
$203
This Southwest deal was found by Cheapflights users on 9/3. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 10/188:15 am -
Nonstop1h 10m
Wed 10/213:35 pm -
2 stops6h 45m
Deal found 9/3![Southwest logo]()
$253
This United Airlines deal was found by Cheapflights users on 8/31. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 10/87:50 pm -
Nonstop1h 31m
Fri 10/96:00 am -
Nonstop1h 36m
Deal found 8/31![United Airlines logo]()
$259
This Contour deal was found by Cheapflights users on 9/2. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Contour is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 9/1711:15 am -
Nonstop1h 35m
Mon 9/219:50 am -
Nonstop1h 55m
Deal found 9/2![Contour logo]()
$203
This Delta deal was found by Cheapflights users on 9/3. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 10/95:30 pm -
1 stop5h 51m
Sun 10/116:47 am -
1 stop5h 54m
Deal found 9/3![Delta logo]()
$279
This United Airlines deal was found by Cheapflights users on 8/31. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 10/222:12 pm -
Nonstop1h 31m
Mon 10/261:08 pm -
Nonstop1h 27m
Deal found 8/31![United Airlines logo]()
$259
This Southwest deal was found by Cheapflights users on 9/1. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 9/256:20 am -
Nonstop1h 25m
Mon 9/285:30 pm -
Nonstop1h 25m
Deal found 9/1![Southwest logo]()
$268
This Contour deal was found by Cheapflights users on 9/2. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Contour is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 11/611:15 am -
Nonstop1h 35m
Wed 12/309:40 am -
Nonstop1h 55m
Deal found 9/2![Contour logo]()
$203
This American Airlines deal was found by Cheapflights users on 9/5. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 9/191:28 pm -
Nonstop1h 33m
Mon 9/2110:38 am -
Nonstop1h 33m
Deal found 9/5![American Airlines logo]()
$299
This United Airlines deal was found by Cheapflights users on 9/3. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 10/912:45 pm -
Nonstop1h 32m
Sun 10/116:00 am -
Nonstop1h 36m
Deal found 9/3![United Airlines logo]()
$259
This Southwest deal was found by Cheapflights users on 9/5. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 10/55:50 pm -
Nonstop1h 10m
Mon 10/126:10 pm -
Nonstop1h 05m
Deal found 9/5![Southwest logo]()
$269
This Delta deal was found by Cheapflights users on 9/3. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 11/31:23 pm -
1 stop7h 56m
Sat 11/712:11 pm -
1 stop4h 47m
Deal found 9/3![Delta logo]()
$299
This United Airlines deal was found by Cheapflights users on 9/5. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 10/59:30 pm -
Nonstop1h 29m
Mon 10/129:04 am -
Nonstop1h 36m
Deal found 9/5![United Airlines logo]()
$269
This Delta deal was found by Cheapflights users on 9/3. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 1/285:30 am -
1 stop5h 41m
Tue 2/25:00 pm -
1 stop5h 20m
Deal found 9/3![Delta logo]()
$299
This Southwest deal was found by Cheapflights users on 8/31. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 9/285:55 pm -
1 stop5h 25m
Mon 10/53:35 pm -
1 stop5h 50m
Deal found 8/31![Southwest logo]()
$277
This KAYAK deal was found by Cheapflights users on 9/3. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure KAYAK is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 10/279:29 am -
Nonstop1h 21m
Tue 10/273:30 pm -
1 stop7h 30m
Deal found 9/3![American Airlines logo]()
$345
This United Airlines deal was found by Cheapflights users on 9/4. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 10/310:40 am -
Nonstop1h 34m
Sat 10/1010:27 am -
Nonstop1h 32m
Deal found 9/4![United Airlines logo]()
$269
This Delta deal was found by Cheapflights users on 9/3. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 11/34:19 pm -
1 stop5h 00m
Sat 11/76:00 am -
1 stop4h 37m
Deal found 9/3![Delta logo]()
$299
This Southwest deal was found by Cheapflights users on 9/2. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 10/236:25 pm -
1 stop5h 25m
Sun 10/253:55 pm -
1 stop6h 05m
Deal found 9/2![Southwest logo]()
$279
This United Airlines deal was found by Cheapflights users on 9/3. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 10/229:00 am -
Nonstop1h 39m
Mon 10/263:00 pm -
Nonstop1h 47m
Deal found 9/3![United Airlines logo]()
$269
This Delta deal was found by Cheapflights users on 9/1. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 10/299:59 am -
2 stops12h 20m
Tue 11/31:00 pm -
1 stop7h 38m
Deal found 9/1![Delta logo]()
$304
Last-minute flights from Chicago to MissouriDiscover last-minute flight deals from Chicago to Missouri. Data last updated September 5, 2026 and is based on user searches.
Discover last-minute flight deals from Chicago to Missouri. Data last updated September 5, 2026 and is based on user searches.
This Southwest deal was found by Cheapflights users on 8/31. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 9/245:55 am -
1 stop4h 15m
Fri 9/255:40 pm -
1 stop4h 45m
Deal found 8/31![Southwest logo]()
$154
This CheapOair deal was found by Cheapflights users on 9/1. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure CheapOair is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 9/2411:15 am -
1 stop6h 39m
Tue 9/2912:17 pm -
1 stop17h 21m
Deal found 9/1![Frontier logo]()
$160
This Frontier deal was found by Cheapflights users on 9/1. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Frontier is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 9/2411:15 am -
1 stop6h 39m
Mon 9/2812:17 pm -
1 stop17h 21m
Deal found 9/1![Frontier logo]()
$168
This Frontier deal was found by Cheapflights users on 9/1. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Frontier is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 9/266:30 am -
1 stop12h 47m
Mon 9/2812:17 pm -
1 stop17h 21m
Deal found 9/1![Frontier logo]()
$151
This Delta deal was found by Cheapflights users on 9/2. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 9/285:50 pm -
1 stop5h 26m
Tue 9/295:47 pm -
1 stop3h 46m
Deal found 9/2![Delta logo]()
$164
This Delta deal was found by Cheapflights users on 9/1. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 9/291:19 pm -
1 stop3h 51m
Thu 10/16:40 am -
1 stop5h 59m
Deal found 9/1![Delta logo]()
$157
This Delta deal was found by Cheapflights users on 9/2. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 10/1011:09 am -
1 stop4h 28m
Mon 10/126:47 am -
1 stop6h 12m
Deal found 9/2![Delta logo]()
$157
This eDestinos deal was found by Cheapflights users on 9/5. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure eDestinos is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 10/1511:15 am -
Nonstop1h 35m
Wed 10/219:40 am -
Nonstop1h 55m
Deal found 9/5![Contour logo]()
$175
This Southwest deal was found by Cheapflights users on 9/1. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 10/167:50 am -
Nonstop1h 10m
Fri 10/236:10 pm -
Nonstop1h 05m
Deal found 9/1![Southwest logo]()
$151
This American Airlines deal was found by Cheapflights users on 9/1. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 10/1611:00 pm -
Nonstop1h 19m
Fri 10/2311:31 am -
Nonstop1h 28m
Deal found 9/1![American Airlines logo]()
$153
This iWofly deal was found by Cheapflights users on 9/1. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure iWofly is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 10/166:20 am -
1 stop10h 38m
Fri 10/238:00 pm -
1 stop28h 24m
Deal found 9/1![Frontier logo]()
$166
This Kiwi.com deal was found by Cheapflights users on 9/4. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 10/286:16 am -
1 stop11h 24m
Fri 10/306:44 pm -
1 stop23h 03m
Deal found 9/4![Frontier logo]()
$175
One-way flights from Chicago to MissouriSearch for one-way flight options from Chicago to Missouri. Find affordable one-way fares based on user searches. Data last updated September 5, 2026.
Search for one-way flight options from Chicago to Missouri. Find affordable one-way fares based on user searches. Data last updated September 5, 2026.
This Southwest deal was found by Cheapflights users on 9/1. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 9/304:40 pm -
Nonstop1h 15m
Wed 12/3112:00 am -
Nonstop0h 00m
Deal found 9/1![Southwest logo]()
$59
This American Airlines deal was found by Cheapflights users on 9/3. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 10/267:34 pm -
Nonstop1h 23m
Wed 12/3112:00 am -
Nonstop0h 00m
Deal found 9/3![American Airlines logo]()
$59
This CheapOair deal was found by Cheapflights users on 9/2. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure CheapOair is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 9/286:25 am -
1 stop6h 45m
Wed 12/3112:00 am -
Nonstop0h 00m
Deal found 9/2![Frontier logo]()
$60
This Frontier deal was found by Cheapflights users on 9/1. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Frontier is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 11/186:30 am -
1 stop8h 53m
Wed 12/3112:00 am -
Nonstop0h 00m
Deal found 9/1![Frontier logo]()
$60
This Frontier deal was found by Cheapflights users on 9/3. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Frontier is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 10/2610:26 am -
1 stop7h 14m
Wed 12/3112:00 am -
Nonstop0h 00m
Deal found 9/3![Frontier logo]()
$61
This Super.com deal was found by Cheapflights users on 9/1. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Super.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 10/216:21 am -
1 stop11h 19m
Wed 12/3112:00 am -
Nonstop0h 00m
Deal found 9/1![Frontier logo]()
$64
This Super.com deal was found by Cheapflights users on 9/3. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Super.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 10/216:30 am -
1 stop8h 54m
Wed 12/3112:00 am -
Nonstop0h 00m
Deal found 9/3![Frontier logo]()
$64
This Trip.com deal was found by Cheapflights users on 9/3. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Trip.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 10/266:15 am -
1 stop11h 25m
Wed 12/3112:00 am -
Nonstop0h 00m
Deal found 9/3![Frontier logo]()
$65
This Frontier deal was found by Cheapflights users on 9/2. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Frontier is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 9/288:55 pm -
1 stop14h 37m
Wed 12/3112:00 am -
Nonstop0h 00m
Deal found 9/2![Frontier logo]()
$65
This Southwest deal was found by Cheapflights users on 9/4. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 9/265:55 am -
1 stop4h 55m
Wed 12/3112:00 am -
Nonstop0h 00m
Deal found 9/4![Southwest logo]()
$69
This Southwest deal was found by Cheapflights users on 9/1. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 10/61:05 pm -
2 stops5h 55m
Wed 12/3112:00 am -
Nonstop0h 00m
Deal found 9/1![Southwest logo]()
$74
This Southwest deal was found by Cheapflights users on 9/2. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 10/211:05 am -
Nonstop1h 10m
Wed 12/3112:00 am -
Nonstop0h 00m
Deal found 9/2![Southwest logo]()
$76
Find flight deals from Chicago to Missouri
Keep the following information in mind while searching for Chicago to Missouri flight deals. Data was last updated September 5, 2026.
Most accurate provider | FlightHub 3 stars |
|---|---|
Most trusted provider | FlightHub 3 stars |
Round-trip from | $151 (Southwest) |
One-way from | $59 (Southwest) |
Popular in | April |
Cheapest in | December |
Average price | $417 |
Good round-trip deal | $239 or less |
Good one-way deal | $125 or less |
Cheapflights Fare Finder
Customize your flight search to find flights from Chicago to Missouri that fit within your specific budget. Explore options based on user searches and filter the results based on your desired price range. Find flights that match your budget for a cost-effective journey. Over the last 7 days, Cheapflights users made 7,457,451 searches. Data last updated September 5, 2026.
Use the filters below to find and compare flights from Chicago to Missouri that are best for you.
Fly from
Fly to
Route
Depart
Return
Cheapest round-trip
ChicagoSt. Louis
MDW Chicago Midway - STL Lambert-St Louis
MDWSTL
Chicago Midway
Wed 9/30
4:40 pm-5:55 pm
Nonstop1h 15m
Lambert-St Louis
Wed 12/31
12:00 am-12:00 am
Nonstop0h 00m
$59
ChicagoSt. Louis
MDW Chicago Midway - STL Lambert-St Louis
MDWSTL
Chicago Midway
Wed 12/2
9:40 am-11:00 am
Nonstop1h 20m
Lambert-St Louis
Wed 12/31
12:00 am-12:00 am
Nonstop0h 00m
$59
ChicagoSt. Louis
MDW Chicago Midway - STL Lambert-St Louis
MDWSTL
Chicago Midway
Thu 11/26
5:40 am-6:55 am
Nonstop1h 15m
Lambert-St Louis
Wed 12/31
12:00 am-12:00 am
Nonstop0h 00m
$59
ChicagoSt. Louis
MDW Chicago Midway - STL Lambert-St Louis
MDWSTL
Chicago Midway
Mon 10/12
10:05 pm-11:20 pm
Nonstop1h 15m
Lambert-St Louis
Wed 12/31
12:00 am-12:00 am
Nonstop0h 00m
$59
Quickest round-trip
ChicagoSt. Louis
MDW Chicago Midway - STL Lambert-St Louis
MDWSTL
Chicago Midway
Wed 11/18
8:45 pm-9:55 pm
Nonstop1h 10m
Lambert-St Louis
Wed 12/31
12:00 am-12:00 am
Nonstop0h 00m
$59
ChicagoSt. Louis
MDW Chicago Midway - STL Lambert-St Louis
MDWSTL
Chicago Midway
Tue 10/6
9:40 am-10:50 am
Nonstop1h 10m
Lambert-St Louis
Wed 12/31
12:00 am-12:00 am
Nonstop0h 00m
$59
ChicagoSt. Louis
MDW Chicago Midway - STL Lambert-St Louis
MDWSTL
Chicago Midway
Sat 9/26
6:15 pm-7:35 pm
Nonstop1h 20m
Lambert-St Louis
Wed 12/31
12:00 am-12:00 am
Nonstop0h 00m
$59
ChicagoSt. Louis
MDW Chicago Midway - STL Lambert-St Louis
MDWSTL
Chicago Midway
Fri 10/2
11:05 am-12:15 pm
Nonstop1h 10m
Lambert-St Louis
Wed 12/31
12:00 am-12:00 am
Nonstop0h 00m
$76
ChicagoSt. Louis
MDW Chicago Midway - STL Lambert-St Louis
MDWSTL
Chicago Midway
Tue 11/3
5:31 pm-9:25 pm
1 stop3h 54m
Lambert-St Louis
Wed 12/31
12:00 am-12:00 am
Nonstop0h 00m
$79
ChicagoSt. Louis
MDW Chicago Midway - STL Lambert-St Louis
MDWSTL
Chicago Midway
Tue 9/29
9:29 am-1:06 pm
1 stop3h 37m
Lambert-St Louis
Wed 12/31
12:00 am-12:00 am
Nonstop0h 00m
$79
Showing 1-10 of 60 resultsSorted by cheapest first
Best time to book a flight from Chicago to Missouri
Have a flexible travel schedule? Discover the best time to fly to Missouri from Chicago with our price prediction graph.
MDW-STL
ORD-STL
ORD-CGI
MDW-MCI
MDW-SGF
Estimated round-trip price
Rates are based on past data. Find the cheapest month and day to book your flight based on your travel requirements, then search for cheap deals.
Cheapflights Insights
Everything you need to know about your flight from Chicago to Missouri
CHI-USMO
MDW-STL
ORD-STL
ORD-CGI
MDW-MCI
What is the cheapest month to book a flight from Chicago to Missouri?
Currently, October is the cheapest month in which you can book a flight from Chicago to Missouri (average of $299). Flying from Chicago to Missouri in June is currently the most expensive (average of $452). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.
What is the cheapest time of day to fly from CHI to MO?
Find hourly flight availability from Chicago to Missouri. Discover flight options and departure times throughout the day, allowing you to choose a departure time that suits your schedule. Data last updated September 5, 2026.
It’s optimal to fly from Chicago to Missouri in the morning. By choosing this option you can save up to 13% on the cost of your flight, compared to a flight in the evening.
Weekly flight availability from Chicago to Missouri
Explore weekly flight availability from Chicago to Missouri. Discover flights operating on different days of the week, giving you the flexibility to choose a travel day that best fits your plans. Compare info to find the most convenient option for your journey. Data last updated September 5, 2026.
The most flights from CHI to USMO are scheduled on a Friday (72 on average). You will have fewer flight options on Wednesday, which is when the least amount of flights are scheduled (12 on average).
How much does it cost to fly round-trip from Chicago to Missouri?
Airfare is below average for this route at the moment.
Chicago to Missouri flights typically cost between $267 and $509 in October.The cheapest round-trip price found within the last 5 days was $151 on Southwest (Oct 16-Oct 23).
How far ahead should I book a flight from Chicago to Missouri?
To ensure you get the cheapest price possible for a flight from Chicago to Missouri, you should look to book at least 72 days in advance of your intended travel date. The price of your flight may increase if you delay and leave booking until a week or so before departure.
What is the cheapest day to fly from Chicago to Missouri?
Use this chart to determine the cheapest time to fly round-trip from Chicago to Missouri. Price data was last updated on September 5, 2026.
Travelers seeking maximum savings on their Chicago to Missouri flight should consider departing on Saturday mornings when fares are most often at their lowest. Wednesday at noon flights should be avoided if possible as fares are typically the most expensive at this time.
Reviews of airlines servicing Missouri
Get insights into the airlines that provide service to Missouri. Read reviews, discover amenities, and learn about the overall travel experience offered by airlines. Use this information to make informed decisions when choosing an airline for your flight to Missouri. Reviews last updated September 5, 2026.
Get a feel of what it's like to fly with Southwest,Contour, andUnited Airlines from Chicago to Missouri by reading reviews from past customers. You can also see how each airline compares in terms of entertainment options, comfort, food, crew/service, and boarding process.
Boarding
8.1
Overall
8.0
Crew
8.6
Food
7.0
Comfort
8.0
Entertainment
7.5
Reviews
1 / 20
10.0
ExcellentCourtney,Sep 2026
DEN - STL
Boarding
8.1
Overall
8.0
Crew
8.6
Food
7.0
Comfort
8.0
Entertainment
7.5
Reviews
1 / 20
10.0
ExcellentCourtney,Sep 2026
DEN - STL
Boarding
8.1
Overall
8.0
Crew
8.6
Food
7.0
Comfort
8.0
Entertainment
7.5
Reviews
1 / 20
10.0
ExcellentCourtney,Sep 2026
DEN - STL
Boarding
8.1
Overall
8.0
Crew
8.6
Food
7.0
Comfort
8.0
Entertainment
7.5
Reviews
1 / 20
10.0
ExcellentCourtney,Sep 2026
DEN - STL
Boarding
8.1
Overall
8.0
Crew
8.6
Food
7.0
Comfort
8.0
Entertainment
7.5
Reviews
1 / 20
10.0
ExcellentCourtney,Sep 2026
DEN - STL
Boarding
8.1
Overall
8.0
Crew
8.6
Food
7.0
Comfort
8.0
Entertainment
7.5
Reviews
1 / 20
10.0
ExcellentCourtney,Sep 2026
DEN - STL
Related info for your journey
Find useful and relevant information for your journey from Chicago to Missouri. Access travel guides, tips, and recommendations to enhance your travel experience. Get information about local attractions, weather, transportation options, and more.
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Alternative routes for Chicago to Missouri
See prices for flight routes from nearby airports that may be better suited for you.
Complete your trip
Complete your trip to Missouri by adding a car rental and/or hotel reservation to your travel itinerary.
Search flights from Chicago to Missouri by cabin class
Find flights from Chicago to Missouri, based on your preferred cabin class, be it economy, premium economy, business, or first class.
Chicago and Missouri flights
Browse other Chicago and Missouri flight options. Last updated on September 5, 2026.
Popular flight searches
Check out other popular destinations found by fellow travelers in 2026
Chicago to Missouri flights
Consider these flights traveling from Chicago to Missouri.
Top 5 airlines flying from Chicago to Missouri
Discover the top 5 airlines that operate flights from Chicago to Missouri. Compare their services, reliability, and customer satisfaction ratings to choose the airline that best suits your travel preferences and needs. Over the last 7 days, Cheapflights users made 7,457,451 searches. Data last updated September 5, 2026.
| Airline | Cheapest | Average | Flexibility | On-time |
|---|---|---|---|---|
| Cheapest$104 | Average$150 | FlexibilityNo cancel fee | On-timeN/A | |
| Cheapest$165 | Average$213 | FlexibilityNo cancel fee | On-timeN/A | |
| Cheapest$171 | Average$333 | FlexibilityNo cancel fee | On-time71% | |
| Cheapest$178 | Average$437 | FlexibilityNo cancel fee | On-time69% | |
| Cheapest$197 | Average$448 | FlexibilityNo cancel fee | On-time63% |