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$49+ Cheap flights from Chicago (CHI) to Missouri

This is the cheapest one-way flight price found by a Cheapflights user in the last 72 hours by searching for a flight departing on 12/25. Fares are subject to change and may not be available on all flights or dates of travel.
CHI — STL
Dec 19 — Dec 261
Fri 12/19
Fri 12/26
1 adult, Economy
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Cheap flight deals from Chicago to Missouri

Keep the following information in mind while searching for Chicago to Missouri flight deals. Data was last updated November 19, 2025.

Most accurate provider

eDreams
3 stars

Most trusted provider

eDreams
3 stars

Round-trip from

$122
(Mytrip)

One-way from

$49
(Southwest)

Popular in

October

Cheapest in

August

Average price

$318

Good round-trip deal

$129 or less

Good one-way deal

$64 or less
Provider with most accurate pricing for Chicago (CHI)-Lambert-St Louis flight deals.
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Provider most trusted by Cheapflights users for Chicago (CHI)-Lambert-St Louis flights.
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From Chicago (CHI) to Missouri
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One-way flight from Chicago (CHI) to Missouri
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Highest demand for flights based on searches. 6% potential increase in price ($19 potential increase over avg. RT price).
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Cheapest flight prices on average. 1% potential price decrease ($7 potential savings vs. average RT price).
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Average for round-trip flights in November 2025
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Price to beat on a round-trip flight from Chicago (CHI) to Missouri.
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Price to beat on a one-way flight from Chicago (CHI) to Missouri.
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Find flight deals from Chicago to Missouri

Cheapest flights from Chicago to Missouri
Explore the most affordable flight options available from Chicago to Missouri. Find the lowest fares from popular airlines and budget airlines, with prices last updated on November 19, 2025.

This Mytrip deal was found by Cheapflights users on 11/19. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Mytrip is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 12/2611:50 amORD - CGI
Nonstop1h 35mContour
Fri 1/29:30 amCGI - ORD
Nonstop1h 40mContour
Deal found 11/19$122
This Mytrip deal was found by Cheapflights users on 11/18. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Mytrip is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 12/1711:50 amORD - CGI
Nonstop1h 35mContour
Wed 12/249:30 amCGI - ORD
Nonstop1h 40mContour
Deal found 11/18$126
This United Airlines deal was found by Cheapflights users on 11/18. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 12/2412:56 pmORD - STL
Nonstop1h 30mUnited Airlines
Wed 12/246:35 pmSTL - ORD
Nonstop1h 44mUnited Airlines
Deal found 11/18$127
This Mytrip deal was found by Cheapflights users on 11/18. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Mytrip is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 12/311:50 amORD - CGI
Nonstop1h 35mContour
Sun 12/79:30 amCGI - ORD
Nonstop1h 40mContour
Deal found 11/18$128
This Contour deal was found by Cheapflights users on 11/18. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Contour is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 12/311:50 amORD - CGI
Nonstop1h 35mContour
Sat 12/69:30 amCGI - ORD
Nonstop1h 40mContour
Deal found 11/18$139
This Kiwi.com deal was found by Cheapflights users on 11/19. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 12/117:23 pmMDW - STL
1 stop14h 24mFrontier
Sun 12/1410:42 amSTL - MDW
1 stop23h 10mFrontier
Deal found 11/19$147
This Frontier deal was found by Cheapflights users on 11/19. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Frontier is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 12/113:10 pmMDW - STL
1 stop7h 23mFrontier
Thu 1/83:43 pmSTL - MDW
1 stop6h 34mFrontier
Deal found 11/19$150
This Frontier deal was found by Cheapflights users on 11/19. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Frontier is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 12/49:53 pmORD - STL
1 stop13h 29mFrontier
Mon 12/812:07 pmSTL - ORD
1 stop8h 10mFrontier
Deal found 11/19$150
This American Airlines deal was found by Cheapflights users on 11/18. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 12/317:14 amORD - STL
Nonstop1h 34mAmerican Airlines
Tue 1/1311:05 amSTL - ORD
Nonstop1h 29mAmerican Airlines
Deal found 11/18$151
This Southwest deal was found by Cheapflights users on 11/19. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 12/171:45 pmMDW - STL
1 stop5h 45mSouthwest
Wed 12/244:25 pmSTL - MDW
Nonstop1h 10mSouthwest
Deal found 11/19$157
This Delta deal was found by Cheapflights users on 11/18. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 12/244:01 pmORD - STL
1 stop6h 15mDelta
Thu 12/251:22 pmSTL - ORD
1 stop6h 16mDelta
Deal found 11/18$157
This Kiwi.com deal was found by Cheapflights users on 11/18. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 12/102:49 pmMDW - STL
1 stop20h 18mFrontier
Sat 12/137:43 pmSTL - MDW
1 stop15h 25mFrontier
Deal found 11/18$162

Cheapflights Fare Finder

 
Customize your flight search to find flights from Chicago to Missouri that fit within your specific budget. Explore options based on user searches and filter the results based on your desired price range. Find flights that match your budget for a cost-effective journey. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated November 19, 2025.
Use the filters below to find and compare flights from Chicago to Missouri that are best for you.

Fly from

Chicago

Fly to

Missouri

Route

Depart

Return

Price

ChicagoCape Girardeau

ORD - CGI

ORDCGI

Chicago O'Hare Intl

Wed 12/17

11:50 am-1:25 pm

Nonstop1h 35m

Cape Girardeau

Wed 12/24

9:30 am-11:10 am

Nonstop1h 40m

$126

ChicagoCape Girardeau

ORD - CGI

ORDCGI

Chicago O'Hare Intl

Tue 12/2

11:50 am-1:25 pm

Nonstop1h 35m

Cape Girardeau

Fri 12/5

9:30 am-11:10 am

Nonstop1h 40m

$128

ChicagoCape Girardeau

ORD - CGI

ORDCGI

Chicago O'Hare Intl

Wed 12/3

11:50 am-1:25 pm

Nonstop1h 35m

Cape Girardeau

Sun 12/7

9:30 am-11:10 am

Nonstop1h 40m

$128

ChicagoCape Girardeau

ORD - CGI

ORDCGI

Chicago O'Hare Intl

Sat 12/6

11:50 am-1:25 pm

Nonstop1h 35m

Cape Girardeau

Sun 12/7

9:30 am-11:10 am

Nonstop1h 40m

$129

ChicagoSt. Louis

ORD - STL

ORDSTL

Chicago O'Hare Intl

Fri 1/23

12:07 pm-6:44 pm

1 stop6h 37m

Lambert-St Louis

Sun 1/25

4:45 pm-10:41 am

1 stop17h 56m

$131

ChicagoCape Girardeau

ORD - CGI

ORDCGI

Chicago O'Hare Intl

Tue 3/10

11:50 am-1:25 pm

Nonstop1h 35m

Cape Girardeau

Wed 3/11

9:30 am-11:10 am

Nonstop1h 40m

$139

ChicagoCape Girardeau

ORD - CGI

ORDCGI

Chicago O'Hare Intl

Wed 12/3

11:50 am-1:25 pm

Nonstop1h 35m

Cape Girardeau

Sat 12/6

9:30 am-11:10 am

Nonstop1h 40m

$139

ChicagoCape Girardeau

ORD - CGI

ORDCGI

Chicago O'Hare Intl

Thu 3/19

11:50 am-1:25 pm

Nonstop1h 35m

Cape Girardeau

Mon 3/23

9:30 am-11:10 am

Nonstop1h 40m

$148

ChicagoSt. Louis

ORD - STL

ORDSTL

Chicago O'Hare Intl

Thu 12/11

9:53 pm-11:22 am

1 stop13h 29m

Lambert-St Louis

Thu 1/8

3:43 pm-10:39 pm

1 stop6h 56m

$150

ChicagoSt. Louis

MDW - STL

MDWSTL

Chicago Midway

Thu 1/1

8:25 am-9:40 am

Nonstop1h 15m

Lambert-St Louis

Mon 1/5

6:40 am-7:50 am

Nonstop1h 10m

$156

Flights are sorted by cheapest round-trip flights first.

Deals found on 11/19

Showing 1-10 of 60 results
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Best time to book a flight from Chicago to Missouri

Have a flexible travel schedule? Discover the best time to fly to Missouri from Chicago with our price prediction graph.
Estimated round-trip price
Rates are based on past data. Find the cheapest month and day to book your flight based on your travel requirements, then search for cheap deals.

Cheapflights Insights

Everything you need to know about your flight from Chicago to Missouri

What is the cheapest month to book a flight from Chicago to Missouri?

Currently, August is the cheapest month in which you can book a flight from Chicago to Missouri (average of $77). Flying from Chicago to Missouri in February is currently the most expensive (average of $160). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.

What is the cheapest time of day to fly from CHI to MO?

Find hourly flight availability from Chicago to Missouri. Discover flight options and departure times throughout the day, allowing you to choose a departure time that suits your schedule. Data last updated November 19, 2025.

It’s optimal to fly from Chicago to Missouri in the evening. By choosing this option you can save up to 11% on the cost of your flight, compared to a flight in the afternoon.

What is the cheapest day to fly from Chicago to Missouri?

Use this chart to determine the cheapest time to fly round-trip from Chicago to Missouri. Price data was last updated on December 16, 2024.

Travelers seeking maximum savings on their Chicago to Missouri flight should consider departing on Friday afternoons when fares are most often at their lowest. Saturday afternoons flights should be avoided if possible as fares are typically the most expensive at this time.

Weekly flight availability from Chicago to Missouri

Explore weekly flight availability from Chicago to Missouri. Discover flights operating on different days of the week, giving you the flexibility to choose a travel day that best fits your plans. Compare info to find the most convenient option for your journey. Data last updated November 19, 2025.

The most flights from CHI to USMO are scheduled on a Tuesday (57 on average). You will have fewer flight options on Saturday, which is when the least amount of flights are scheduled (27 on average).

How much does it cost to fly round-trip from Chicago to Missouri?

Reviews of airlines servicing Missouri

Get insights into the airlines that provide service to Missouri. Read reviews, discover amenities, and learn about the overall travel experience offered by airlines. Use this information to make informed decisions when choosing an airline for your flight to Missouri. Reviews last updated November 19, 2025.
Get a feel of what it's like to fly with Southwest, Contour, and United Airlines from Chicago to Missouri by reading reviews from past customers. You can also see how each airline compares in terms of entertainment options, comfort, food, crew/service, and boarding process.
Southwest
8.0
Very good
4,249 reviews

Entertainment

7.5

Food

7.0

Boarding

8.1

Comfort

8.0

Crew

8.6

Overall

8.0

Reviews

1 / 20
2.0
Mediocre

Mike,Aug 2025

OKC - AUS

AC was not adequate, even on a night flight. WiFi subpar even for the airlines
Southwest
8.0
Very good
4,249 reviews
Southwest
8.0
Very good
4,249 reviews

Entertainment

7.5

Food

7.0

Boarding

8.1

Comfort

8.0

Crew

8.6

Overall

8.0

Reviews

1 / 20
2.0
Mediocre

Mike,Aug 2025

OKC - AUS

AC was not adequate, even on a night flight. WiFi subpar even for the airlines
Contour
7.5
Good
41 reviews
Southwest
8.0
Very good
4,249 reviews

Entertainment

7.5

Food

7.0

Boarding

8.1

Comfort

8.0

Crew

8.6

Overall

8.0

Reviews

1 / 20
2.0
Mediocre

Mike,Aug 2025

OKC - AUS

AC was not adequate, even on a night flight. WiFi subpar even for the airlines
United Airlines
7.4
Good
9,027 reviews
Southwest
8.0
Very good
4,249 reviews

Entertainment

7.5

Food

7.0

Boarding

8.1

Comfort

8.0

Crew

8.6

Overall

8.0

Reviews

1 / 20
2.0
Mediocre

Mike,Aug 2025

OKC - AUS

AC was not adequate, even on a night flight. WiFi subpar even for the airlines
American Airlines
7.2
Good
11,045 reviews
Southwest
8.0
Very good
4,249 reviews

Entertainment

7.5

Food

7.0

Boarding

8.1

Comfort

8.0

Crew

8.6

Overall

8.0

Reviews

1 / 20
2.0
Mediocre

Mike,Aug 2025

OKC - AUS

AC was not adequate, even on a night flight. WiFi subpar even for the airlines
Southern / Mokulele
6.4
Okay
27 reviews
Southwest
8.0
Very good
4,249 reviews

Entertainment

7.5

Food

7.0

Boarding

8.1

Comfort

8.0

Crew

8.6

Overall

8.0

Reviews

1 / 20
2.0
Mediocre

Mike,Aug 2025

OKC - AUS

AC was not adequate, even on a night flight. WiFi subpar even for the airlines

Related info for your journey

Find useful and relevant information for your journey from Chicago to Missouri. Access travel guides, tips, and recommendations to enhance your travel experience. Get information about local attractions, weather, transportation options, and more.

  • How long is the flight from Chicago to Missouri?

    Airlines like Contour, Frontier, and Southwest fly from Chicago to Missouri in about 1h 15m. The time it takes to get you to your destination can typically vary by up to 5h 22m. The distance between Chicago and Missouri is about 251 mi. When browsing for deals, the options you’ll see will be for both nonstop flights and flights with stops.

  • What are the most popular routes from Chicago to Missouri?

    While some choose either Chicago O'Hare Intl - Lambert-St Louis or Chicago Midway - Kansas City, Chicago O'Hare Intl - Kansas City is the most popular route from Chicago to Missouri.

  • What are the most reliable airlines from Chicago to Missouri?

    The top 3 most reliable airlines when flying from Chicago to Missouri are Turkish Airlines (90%), United Airlines (84%) and Envoy Air (84%).

  • What are the cheapest flights from Chicago to Missouri?

    The cheapest flight price from Chicago to Missouri is $63. On average you can expect to pay $283. The most popular route, (Chicago O'Hare Intl - Kansas City), can usually be booked for $187.

  • Can I find deals for flights from Chicago to Missouri that include hotel bookings?

    Yes. In addition to deals on Chicago to Missouri flights, Cheapflights offers vacation packages that include both flights and hotel.

  • How can I find direct flights from Chicago to Missouri?

    After entering your origin and destination, apply the non-stop filter on the search result page to find direct flights from Chicago to Missouri.

  • Can I find deals for business class flights from Chicago to Missouri?

    Yes. Cheapflights offers flight deals from Chicago to Missouri by cabin class. In addition to browsing deals, you can also filter by cabin class on the search results page after making a search.

  • What is the cheapest month to book a flight from Chicago to Missouri?

    Currently, August is the cheapest month in which you can book a flight from Chicago to Missouri (average of $77). Flying from Chicago to Missouri in February is currently the most expensive (average of $160). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.

See more FAQs

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Alternative routes for Chicago to Missouri

See prices for flight routes from nearby airports that may be better suited for you.
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Top 5 airlines flying from Chicago to Missouri

Discover the top 5 airlines that operate flights from Chicago to Missouri. Compare their services, reliability, and customer satisfaction ratings to choose the airline that best suits your travel preferences and needs. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated November 19, 2025.
AirlineCheapestAverageFlexibilityOn-time
SouthwestCheapest$77Average$302FlexibilityNo cancel feeOn-time63%
ContourCheapest$114Average$182FlexibilityNo cancel feeOn-timeN/A
American AirlinesCheapest$115Average$329FlexibilityNo cancel feeOn-time71%
Southern / MokuleleCheapest$145Average$214FlexibilityNo cancel feeOn-timeN/A
United AirlinesCheapest$152Average$323FlexibilityNo cancel feeOn-time69%

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