HomeSearch by dateVacation packagesHotelsFlight dealsCar rentalTravel tips & news
Missouri

$49+ Cheap flights from Chicago (CHI) to Missouri

This is the cheapest one-way flight price found by a Cheapflights user in the last 72 hours by searching for a flight departing on 11/13. Fares are subject to change and may not be available on all flights or dates of travel.
CHI — STL
oct. 17 — oct. 241
vie. 10/17
vie. 10/24
1 adult, Economy
We work with more than 300 partners to bring you better travel deals

Find cheap flights from Chicago to Missouri with Cheapflights

1. Tell us where you want to go

Enter your travel information like dates, passengers, trip type (one-way or round trip), and preferred cabin class then click “Find deals”

2. Select your favorite providers

We find the providers serving your travel needs. Choose up to four travel providers to compare side-by-side for flights, hotels, or car rentals.

3. Compare prices and book

Review each provider’s pricing and select the best option for you! Book through your favorite provider’s website for a seamless experience.

Cheap flight deals from Chicago to Missouri

Keep the following information in mind while searching for Chicago to Missouri flight deals. Data was last updated septiembre 17, 2025.

Round-trip from

$97
(Southwest)

One-way from

$49
(Southwest)

Popular in

December

Cheapest in

October

Average price

$308

Good round-trip deal

$138 or less

Good one-way deal

$81 or less
From Chicago (CHI) to Missouri
Search Deals
One-way flight from Chicago (CHI) to Missouri
Search Deals
Highest demand for flights based on searches. 0% potential increase in price ($3 potential increase over avg. RT price).
Search Deals
Cheapest flight prices on average. 0% potential price decrease ($3 potential savings vs. average RT price).
Search Deals
Average for round-trip flights in September 2025
Search Deals
Price to beat on a round-trip flight from Chicago (CHI) to Missouri.
Search Deals
Price to beat on a one-way flight from Chicago (CHI) to Missouri.
Search Deals

Find flight deals from Chicago to Missouri

Cheapest flights from Chicago to Missouri
Explore the most affordable flight options available from Chicago to Missouri. Find the lowest fares from popular airlines and budget airlines, with prices last updated on septiembre 17, 2025.

This Southwest deal was found by Cheapflights users on 9/15. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
mié. 10/1512:40 pmMDW - STL
Nonstop1h 10mSouthwest
mié. 10/221:15 pmSTL - MDW
Nonstop1h 10mSouthwest
Deal found 9/15$97
This United Airlines deal was found by Cheapflights users on 9/16. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
mar. 10/142:20 pmORD - STL
Nonstop1h 24mUnited Airlines
mar. 10/213:23 pmSTL - ORD
Nonstop1h 25mUnited Airlines
Deal found 9/16$97
This American Airlines deal was found by Cheapflights users on 9/16. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
jue. 10/96:53 pmORD - STL
Nonstop1h 33mAmerican Airlines
lun. 10/136:00 amSTL - ORD
Nonstop1h 23mAmerican Airlines
Deal found 9/16$98
This Southwest deal was found by Cheapflights users on 9/15. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
lun. 10/206:00 pmMDW - STL
1 stop3h 30mSouthwest
mié. 10/221:15 pmSTL - MDW
Nonstop1h 10mSouthwest
Deal found 9/15$107
This Southwest deal was found by Cheapflights users on 9/16. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
sáb. 10/188:20 amMDW - STL
2 stops6h 10mSouthwest
jue. 10/235:40 amSTL - MDW
Nonstop1h 10mSouthwest
Deal found 9/16$112
This Southwest deal was found by Cheapflights users on 9/15. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
mar. 10/71:30 pmORD - STL
1 stop7h 15mSouthwest
mié. 10/222:55 pmSTL - ORD
1 stop6h 35mSouthwest
Deal found 9/15$117
This Southwest deal was found by Cheapflights users on 9/14. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
sáb. 10/257:00 amORD - STL
1 stop5h 30mSouthwest
sáb. 10/251:45 pmSTL - ORD
2 stops8h 15mSouthwest
Deal found 9/14$122
This Southwest deal was found by Cheapflights users on 9/16. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
mar. 10/712:40 pmMDW - STL
Nonstop1h 10mSouthwest
mié. 10/221:15 pmSTL - MDW
Nonstop1h 10mSouthwest
Deal found 9/16$134
This American Airlines deal was found by Cheapflights users on 9/15. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
mar. 10/216:53 pmORD - STL
Nonstop1h 33mAmerican Airlines
vie. 10/247:16 amSTL - ORD
Nonstop1h 27mAmerican Airlines
Deal found 9/15$134
This Frontier deal was found by Cheapflights users on 9/16. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Frontier is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
vie. 10/315:25 amORD - STL
1 stop7h 52mFrontier
vie. 10/314:52 pmSTL - ORD
1 stop6h 47mFrontier
Deal found 9/16$139
This Priceline deal was found by Cheapflights users on 9/15. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Priceline is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
lun. 9/296:20 amMDW - STL
1 stop8h 44mFrontier
jue. 10/24:00 pmSTL - MDW
1 stop7h 41mFrontier
Deal found 9/15$143
This Priceline deal was found by Cheapflights users on 9/15. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Priceline is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
lun. 9/295:10 amORD - STL
1 stop9h 54mFrontier
jue. 10/24:00 pmSTL - ORD
1 stop7h 39mFrontier
Deal found 9/15$143

Cheapflights Fare Finder

 
Customize your flight search to find flights from Chicago to Missouri that fit within your specific budget. Explore options based on user searches and filter the results based on your desired price range. Find flights that match your budget for a cost-effective journey. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated septiembre 17, 2025.
Use the filters below to find and compare flights from Chicago to Missouri that are best for you.

Fly from

Chicago

Fly to

Missouri

Route

Depart

Return

Price

ChicagoSt. Louis

MDW - STL

MDWSTL

Chicago Midway

mar. 10/14

8:40 pm-9:50 pm

Nonstop1h 10m

Lambert-St Louis

mar. 10/21

1:15 pm-2:25 pm

Nonstop1h 10m

$97

ChicagoSt. Louis

ORD - STL

ORDSTL

Chicago O'Hare Intl

mié. 10/22

9:25 am-10:49 am

Nonstop1h 24m

Lambert-St Louis

jue. 10/23

5:00 am-6:30 am

Nonstop1h 30m

$97

ChicagoSt. Louis

MDW - STL

MDWSTL

Chicago Midway

mar. 10/28

7:55 am-9:10 am

Nonstop1h 15m

Lambert-St Louis

jue. 10/30

6:30 pm-7:40 pm

Nonstop1h 10m

$97

ChicagoSt. Louis

ORD - STL

ORDSTL

Chicago O'Hare Intl

mar. 10/14

2:20 pm-3:44 pm

Nonstop1h 24m

Lambert-St Louis

mar. 10/21

3:23 pm-4:48 pm

Nonstop1h 25m

$97

ChicagoSt. Louis

MDW - STL

MDWSTL

Chicago Midway

mié. 10/15

5:30 am-10:15 am

1 stop4h 45m

Lambert-St Louis

mié. 10/15

5:05 pm-6:10 pm

Nonstop1h 05m

$107

ChicagoSt. Louis

MDW - STL

MDWSTL

Chicago Midway

mar. 10/7

10:05 am-3:00 pm

1 stop4h 55m

Lambert-St Louis

mié. 10/22

5:05 pm-6:10 pm

Nonstop1h 05m

$107

ChicagoSt. Louis

MDW - STL

MDWSTL

Chicago Midway

lun. 11/3

10:05 am-4:05 pm

1 stop6h 00m

Lambert-St Louis

lun. 11/3

7:20 pm-8:30 pm

Nonstop1h 10m

$107

ChicagoSt. Louis

MDW - STL

MDWSTL

Chicago Midway

sáb. 10/18

8:15 am-2:40 pm

1 stop6h 25m

Lambert-St Louis

jue. 10/23

5:40 am-6:50 am

Nonstop1h 10m

$107

ChicagoSt. Louis

MDW - STL

MDWSTL

Chicago Midway

lun. 10/20

6:00 pm-9:30 pm

1 stop3h 30m

Lambert-St Louis

mié. 10/22

5:05 pm-6:10 pm

Nonstop1h 05m

$107

ChicagoSt. Louis

MDW - STL

MDWSTL

Chicago Midway

mié. 11/5

3:45 pm-7:25 pm

1 stop3h 40m

Lambert-St Louis

sáb. 11/8

5:45 pm-6:55 pm

Nonstop1h 10m

$107

Flights are sorted by cheapest round-trip flights first.

Deals found on 9/17

Showing 1-10 of 60 results
1
2
3
...
6

Best time to book a flight from Chicago to Missouri

Have a flexible travel schedule? Discover the best time to fly to Missouri from Chicago with our price prediction graph.
Estimated round-trip price
Rates are based on past data. Find the cheapest month and day to book your flight based on your travel requirements, then search for cheap deals.

Cheapflights Insights

Everything you need to know about your flight from Chicago to Missouri

What is the cheapest month to book a flight from Chicago to Missouri?

Currently, August is the cheapest month in which you can book a flight from Chicago to Missouri (average of $311). Flying from Chicago to Missouri in March is currently the most expensive (average of $356). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.

What is the cheapest time of day to fly from CHI to MO?

Find hourly flight availability from Chicago to Missouri. Discover flight options and departure times throughout the day, allowing you to choose a departure time that suits your schedule. Data last updated septiembre 17, 2025.

When flying from Chicago to Missouri, the time of day you decide to fly out makes little to no difference towards the overall price you’ll pay on tickets.

Weekly flight availability from Chicago to Missouri

Explore weekly flight availability from Chicago to Missouri. Discover flights operating on different days of the week, giving you the flexibility to choose a travel day that best fits your plans. Compare info to find the most convenient option for your journey. Data last updated septiembre 17, 2025.

The most flights from CHI to USMO are scheduled on a Monday (76 on average). You will have fewer flight options on Saturday, which is when the least amount of flights are scheduled (46 on average).

Reviews of airlines servicing Missouri

Get insights into the airlines that provide service to Missouri. Read reviews, discover amenities, and learn about the overall travel experience offered by airlines. Use this information to make informed decisions when choosing an airline for your flight to Missouri. Reviews last updated septiembre 17, 2025.
Get a feel of what it's like to fly with Southwest, United Airlines, and American Airlines from Chicago to Missouri by reading reviews from past customers. You can also see how each airline compares in terms of entertainment options, comfort, food, crew/service, and boarding process.
Southwest
8.0
Very good
4,242 reviews

Comfort

8.0

Boarding

8.1

Food

7.0

Crew

8.6

Entertainment

7.5

Overall

8.0

Reviews

1 / 20
2.0
Mediocre

Mike,Aug 2025

OKC - AUS

AC was not adequate, even on a night flight. WiFi subpar even for the airlines
Southwest
8.0
Very good
4,242 reviews
Southwest
8.0
Very good
4,242 reviews

Comfort

8.0

Boarding

8.1

Food

7.0

Crew

8.6

Entertainment

7.5

Overall

8.0

Reviews

1 / 20
2.0
Mediocre

Mike,Aug 2025

OKC - AUS

AC was not adequate, even on a night flight. WiFi subpar even for the airlines
United Airlines
7.4
Good
8,926 reviews
Southwest
8.0
Very good
4,242 reviews

Comfort

8.0

Boarding

8.1

Food

7.0

Crew

8.6

Entertainment

7.5

Overall

8.0

Reviews

1 / 20
2.0
Mediocre

Mike,Aug 2025

OKC - AUS

AC was not adequate, even on a night flight. WiFi subpar even for the airlines
American Airlines
7.2
Good
10,000 reviews
Southwest
8.0
Very good
4,242 reviews

Comfort

8.0

Boarding

8.1

Food

7.0

Crew

8.6

Entertainment

7.5

Overall

8.0

Reviews

1 / 20
2.0
Mediocre

Mike,Aug 2025

OKC - AUS

AC was not adequate, even on a night flight. WiFi subpar even for the airlines
Contour
7.2
Good
36 reviews
Southwest
8.0
Very good
4,242 reviews

Comfort

8.0

Boarding

8.1

Food

7.0

Crew

8.6

Entertainment

7.5

Overall

8.0

Reviews

1 / 20
2.0
Mediocre

Mike,Aug 2025

OKC - AUS

AC was not adequate, even on a night flight. WiFi subpar even for the airlines

Related info for your journey

Find useful and relevant information for your journey from Chicago to Missouri. Access travel guides, tips, and recommendations to enhance your travel experience. Get information about local attractions, weather, transportation options, and more.

  • How long is the flight from Chicago to Missouri?

    Airlines like Southwest, United Airlines, and Contour fly from Chicago to Missouri in about 1h 10m. The time it takes to get you to your destination is usually consistent. The distance between Chicago and Missouri is about 251 mi. Most flights are nonstop.

  • What are the cheapest airlines to fly from Chicago to Missouri one-way?

    The cheapest airline one-way is Southwest, with whom users have recently found tickets for as low as $49. However, be on the lookout for offers from United Airlines and Contour, as they are both options that can get you from Chicago to Missouri for a low price.

  • What are the most popular routes from Chicago to Missouri?

    While some choose either Chicago O'Hare Intl - Lambert-St Louis or Chicago Midway - Kansas City, Chicago O'Hare Intl - Kansas City is the most popular route from Chicago to Missouri.

  • What are the most reliable airlines from Chicago to Missouri?

    The top 3 most reliable airlines when flying from Chicago to Missouri are SkyWest Airlines (81%), ANA (76%) and Envoy Air (73%).

  • What are the cheapest flights from Chicago to Missouri?

    The cheapest flight price from Chicago to Missouri is $48. On average you can expect to pay $279. The most popular route, (Chicago O'Hare Intl - Kansas City), can usually be booked for $154.

  • Can I find deals for flights from Chicago to Missouri that include hotel bookings?

    Yes. In addition to deals on Chicago to Missouri flights, Cheapflights offers vacation packages that include both flights and hotel.

  • How can I find direct flights from Chicago to Missouri?

    After entering your origin and destination, apply the non-stop filter on the search result page to find direct flights from Chicago to Missouri.

  • Can I find deals for business class flights from Chicago to Missouri?

    Yes. Cheapflights offers flight deals from Chicago to Missouri by cabin class. In addition to browsing deals, you can also filter by cabin class on the search results page after making a search.

  • What is the cheapest month to book a flight from Chicago to Missouri?

    Currently, August is the cheapest month in which you can book a flight from Chicago to Missouri (average of $311). Flying from Chicago to Missouri in March is currently the most expensive (average of $356). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.

See more FAQs

Browse thousands of different options on Cheapflights for your next trip

Toggle through the tabs below to find thousands of options on Cheapflights for your next trip.

Alternative routes for Chicago to Missouri

See prices for flight routes from nearby airports that may be better suited for you.
O'Hare Intl to John F Kennedy Intl flights
O'Hare Intl to Dallas/Fort Worth flights
O'Hare Intl to LaGuardia flights
O'Hare Intl to Las Vegas flights
O'Hare Intl to Newark flights
O'Hare Intl to Sky Harbor Intl flights
O'Hare Intl to Los Angeles flights
O'Hare Intl to Seattle flights
Midway to Las Vegas flights
O'Hare Intl to Orlando flights
O'Hare Intl to San Francisco flights
O'Hare Intl to Atlanta flights
Midway to Dallas/Fort Worth flights
O'Hare Intl to Denver flights
O'Hare Intl to Miami flights
O'Hare Intl to Fort Lauderdale flights
O'Hare Intl to Boston flights
O'Hare Intl to Dulles Intl flights
Midway to Sky Harbor Intl flights
O'Hare Intl to Reagan-National flights
O'Hare Intl to Philadelphia flights
O'Hare Intl to Baltimore flights
Midway to Hobby flights
O'Hare Intl to Ontario flights
Midway to Atlanta flights
O'Hare Intl to Santa Ana flights
O'Hare Intl to Tampa flights
O'Hare Intl to Honolulu flights
Midway to John F Kennedy Intl flights
Midway to Los Angeles flights
Midway to LaGuardia flights
O'Hare Intl to Austin flights
O'Hare Intl to Fort Myers flights
St. Louis to Las Vegas flights
O'Hare Intl to San Diego flights
O'Hare Intl to Nashville flights
O'Hare Intl to Hobby flights
Midway to Orlando flights
O'Hare Intl to Love Field flights
O'Hare Intl to New Orleans flights
St. Louis to John F Kennedy Intl flights
O'Hare Intl to Raleigh flights
O'Hare Intl to George Bush Intcntl flights
St. Louis to LaGuardia flights
Midway to Miami flights
Midway to Seattle flights
O'Hare Intl to Salt Lake City flights
O'Hare Intl to Charlotte flights
Midway to Baltimore flights
Midway to Tampa flights

Top 5 airlines flying from Chicago to Missouri

Discover the top 5 airlines that operate flights from Chicago to Missouri. Compare their services, reliability, and customer satisfaction ratings to choose the airline that best suits your travel preferences and needs. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated septiembre 17, 2025.
AirlineCheapestAverageFlexibilityOn-time
SouthwestCheapest$77Average$305FlexibilityNo cancel feeOn-time63%
ContourCheapest$114Average$184FlexibilityNo cancel feeOn-timeN/A
American AirlinesCheapest$116Average$333FlexibilityNo cancel feeOn-time71%
Southern / MokuleleCheapest$118Average$221FlexibilityNo cancel feeOn-timeN/A
United AirlinesCheapest$152Average$338FlexibilityNo cancel feeOn-time69%

100% Free

Cheapflights is completely free to use, so you can start saving the moment you arrive.

Book with Flexibility

Our users can plan ahead with confidence and find flights with no change fees

Travel Smart

Millions of people come to us for their flight needs every year. We help make travel planning easy by providing useful insights and data-driven graphs that can inform your decisions.