$59+ Cheap flights from Chicago (CHI) to Missouri
This is the cheapest one-way flight price found by a Cheapflights user in the last 72 hours by searching for a flight departing on 5/6. Fares are subject to change and may not be available on all flights or dates of travel.
CHI — STL
maig 9 — maig 161
Round-trip
1 adult, Economy
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Find cheap flights from Chicago to Missouri with Cheapflights
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Enter your travel information like dates, passengers, trip type (one-way or round trip), and preferred cabin class then click “Find deals”2. Select your favorite providers
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Cheapest flights from Chicago to MissouriExplore the most affordable flight options available from Chicago to Missouri. Find the lowest fares from popular airlines and budget airlines, with prices last updated on abril 9, 2026.
Explore the most affordable flight options available from Chicago to Missouri. Find the lowest fares from popular airlines and budget airlines, with prices last updated on abril 9, 2026.
This Mytrip deal was found by Cheapflights users on 4/5. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Mytrip is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
dj. 4/2312:10 pm
ORD
- CGI
Nonstop1h 40m
Contour
dv. 4/249:45 am
CGI
- ORD
Nonstop1h 45m
Contour
Deal found 4/5![Contour logo]()
$119
This Mytrip deal was found by Cheapflights users on 4/7. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Mytrip is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
dv. 6/1212:10 pm
ORD
- CGI
Nonstop1h 40m
Contour
dl. 6/159:45 am
CGI
- ORD
Nonstop1h 45m
Contour
Deal found 4/7![Contour logo]()
$121
This Mytrip deal was found by Cheapflights users on 4/6. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Mytrip is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
dv. 4/2412:10 pm
ORD
- CGI
Nonstop1h 40m
Contour
dg. 4/269:45 am
CGI
- ORD
Nonstop1h 45m
Contour
Deal found 4/6![Contour logo]()
$122
This Mytrip deal was found by Cheapflights users on 4/7. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Mytrip is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
dj. 4/2312:10 pm
ORD
- CGI
Nonstop1h 40m
Contour
dg. 4/269:45 am
CGI
- ORD
Nonstop1h 45m
Contour
Deal found 4/7![Contour logo]()
$132
This Contour deal was found by Cheapflights users on 4/6. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Contour is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
ds. 4/2512:10 pm
ORD
- CGI
Nonstop1h 40m
Contour
dt. 4/289:45 am
CGI
- ORD
Nonstop1h 45m
Contour
Deal found 4/6![Contour logo]()
$139
This Booking.com deal was found by Cheapflights users on 4/8. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Booking.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
dj. 6/412:10 pm
ORD
- CGI
Nonstop1h 40m
Contour
dg. 6/79:45 am
CGI
- ORD
Nonstop1h 45m
Contour
Deal found 4/8![Contour logo]()
$152
This Contour deal was found by Cheapflights users on 4/7. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Contour is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
ds. 8/153:55 pm
ORD
- CGI
Nonstop1h 40m
Contour
dc. 8/191:30 pm
CGI
- ORD
Nonstop1h 45m
Contour
Deal found 4/7![Contour logo]()
$178
This Contour deal was found by Cheapflights users on 4/7. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Contour is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
dv. 8/1412:10 pm
ORD
- CGI
Nonstop1h 40m
Contour
dl. 8/249:45 am
CGI
- ORD
Nonstop1h 45m
Contour
Deal found 4/7![Contour logo]()
$188
This Kiwi.com deal was found by Cheapflights users on 4/7. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
dt. 4/2811:28 am
ORD
- STL
1 stop19h 22m
Multiple Airlines
dv. 5/18:23 pm
STL
- ORD
2 stops19h 00m
Multiple Airlines
Deal found 4/7![Multiple Airlines logo]()
$190
This Southwest deal was found by Cheapflights users on 4/7. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
dj. 4/309:30 pm
MDW
- STL
Nonstop1h 15m
Southwest
dl. 5/47:20 am
STL
- MDW
Nonstop1h 10m
Southwest
Deal found 4/7![Southwest logo]()
$191
This American Airlines deal was found by Cheapflights users on 4/8. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
dj. 4/303:18 pm
ORD
- STL
Nonstop1h 23m
American Airlines
dl. 5/44:30 pm
STL
- ORD
Nonstop1h 40m
American Airlines
Deal found 4/8![American Airlines logo]()
$191
This Kiwi.com deal was found by Cheapflights users on 4/7. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
dj. 4/308:21 am
MDW
- STL
1 stop14h 58m
Frontier
dl. 5/48:23 pm
STL
- MDW
1 stop14h 46m
Frontier
Deal found 4/7![Frontier logo]()
$192
Best flights from Chicago to MissouriDiscover carefully curated flight deals from Chicago to Missouri that have cost, travel time, and layovers in mind to ensure you get the best travel experience. Data last updated abril 9, 2026.
Discover carefully curated flight deals from Chicago to Missouri that have cost, travel time, and layovers in mind to ensure you get the best travel experience. Data last updated abril 9, 2026.
This Mytrip deal was found by Cheapflights users on 4/7. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Mytrip is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
dv. 6/1212:10 pm
ORD
- CGI
Nonstop1h 40m
Contour
dl. 6/159:45 am
CGI
- ORD
Nonstop1h 45m
Contour
Deal found 4/7![Contour logo]()
$121
This Southwest deal was found by Cheapflights users on 4/8. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
dj. 4/309:30 pm
MDW
- STL
Nonstop1h 15m
Southwest
dl. 5/49:40 pm
STL
- MDW
Nonstop1h 05m
Southwest
Deal found 4/8![Southwest logo]()
$191
This American Airlines deal was found by Cheapflights users on 4/8. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
dt. 5/511:15 am
ORD
- STL
1 stop5h 48m
American Airlines
dt. 5/127:05 am
STL
- ORD
Nonstop1h 31m
American Airlines
Deal found 4/8![American Airlines logo]()
$197
This United Airlines deal was found by Cheapflights users on 4/5. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
ds. 5/169:20 pm
ORD
- STL
Nonstop1h 25m
United Airlines
dt. 5/197:09 pm
STL
- ORD
Nonstop1h 31m
United Airlines
Deal found 4/5![United Airlines logo]()
$224
This Delta deal was found by Cheapflights users on 4/4. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
ds. 4/259:27 am
MDW
- STL
2 stops7h 23m
Delta
dl. 4/276:48 am
STL
- MDW
1 stop5h 55m
Delta
Deal found 4/4![Delta logo]()
$250
This Contour deal was found by Cheapflights users on 4/4. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Contour is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
ds. 4/2512:10 pm
ORD
- CGI
Nonstop1h 40m
Contour
dt. 4/289:45 am
CGI
- ORD
Nonstop1h 45m
Contour
Deal found 4/4![Contour logo]()
$139
This Contour deal was found by Cheapflights users on 4/5. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Contour is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
dl. 4/2012:10 pm
ORD
- CGI
Nonstop1h 40m
Contour
dv. 4/249:45 am
CGI
- ORD
Nonstop1h 45m
Contour
Deal found 4/5![Contour logo]()
$139
This Southwest deal was found by Cheapflights users on 4/5. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
dl. 5/49:30 pm
MDW
- STL
Nonstop1h 15m
Southwest
dl. 5/1110:15 am
STL
- MDW
1 stop5h 10m
Southwest
Deal found 4/5![Southwest logo]()
$201
This Contour deal was found by Cheapflights users on 4/7. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Contour is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
dc. 8/193:55 pm
ORD
- CGI
Nonstop1h 40m
Contour
dl. 8/249:45 am
CGI
- ORD
Nonstop1h 45m
Contour
Deal found 4/7![Contour logo]()
$178
This Southwest deal was found by Cheapflights users on 4/4. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
ds. 4/255:15 am
MDW
- STL
1 stop6h 10m
Southwest
dl. 4/274:00 pm
STL
- MDW
1 stop6h 20m
Southwest
Deal found 4/4![Southwest logo]()
$211
This Contour deal was found by Cheapflights users on 4/7. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Contour is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
ds. 8/153:55 pm
ORD
- CGI
Nonstop1h 40m
Contour
dl. 8/249:45 am
CGI
- ORD
Nonstop1h 45m
Contour
Deal found 4/7![Contour logo]()
$178
This United Airlines deal was found by Cheapflights users on 4/3. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
dl. 6/298:08 pm
ORD
- COU
Nonstop1h 51m
United Airlines
dt. 8/48:00 am
COU
- ORD
Nonstop1h 40m
United Airlines
Deal found 4/3![United Airlines logo]()
$239
This American Airlines deal was found by Cheapflights users on 4/6. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
dc. 5/67:56 pm
ORD
- COU
Nonstop1h 34m
American Airlines
dc. 5/134:28 pm
COU
- ORD
Nonstop1h 42m
American Airlines
Deal found 4/6![American Airlines logo]()
$239
This Delta deal was found by Cheapflights users on 4/7. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
dg. 5/37:10 am
ORD
- STL
1 stop4h 46m
Delta
dc. 5/612:23 pm
STL
- ORD
2 stops8h 17m
Delta
Deal found 4/7![Delta logo]()
$252
This Southwest deal was found by Cheapflights users on 4/6. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
dl. 4/274:15 pm
ORD
- STL
1 stop6h 25m
Southwest
dj. 4/308:25 am
STL
- ORD
1 stop6h 35m
Southwest
Deal found 4/6![Southwest logo]()
$211
This Contour deal was found by Cheapflights users on 4/7. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Contour is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
dl. 8/1712:10 pm
ORD
- CGI
Nonstop1h 40m
Contour
dj. 8/209:45 am
CGI
- ORD
Nonstop1h 45m
Contour
Deal found 4/7![Contour logo]()
$178
This United Airlines deal was found by Cheapflights users on 4/4. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
ds. 5/28:20 pm
ORD
- COU
Nonstop1h 43m
United Airlines
ds. 5/95:00 am
COU
- ORD
Nonstop1h 30m
United Airlines
Deal found 4/4![United Airlines logo]()
$239
This American Airlines deal was found by Cheapflights users on 4/7. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
dj. 6/184:25 pm
ORD
- COU
Nonstop1h 37m
American Airlines
dg. 6/216:32 pm
COU
- ORD
Nonstop1h 50m
American Airlines
Deal found 4/7![American Airlines logo]()
$239
This Delta deal was found by Cheapflights users on 4/5. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
dv. 5/155:10 pm
MDW
- STL
1 stop6h 49m
Delta
ds. 5/164:00 pm
STL
- MDW
1 stop5h 09m
Delta
Deal found 4/5![Delta logo]()
$254
This Southwest deal was found by Cheapflights users on 4/7. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
dt. 4/2811:35 am
MDW
- STL
2 stops6h 20m
Southwest
dv. 5/19:40 pm
STL
- MDW
Nonstop1h 05m
Southwest
Deal found 4/7![Southwest logo]()
$212
This Contour deal was found by Cheapflights users on 4/7. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Contour is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
dt. 8/1812:10 pm
ORD
- CGI
Nonstop1h 40m
Contour
ds. 8/221:30 pm
CGI
- ORD
Nonstop1h 45m
Contour
Deal found 4/7![Contour logo]()
$178
This American Airlines deal was found by Cheapflights users on 4/3. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
dl. 6/298:20 am
ORD
- COU
Nonstop1h 40m
American Airlines
dt. 8/45:19 pm
COU
- ORD
1 stop7h 12m
American Airlines
Deal found 4/3![American Airlines logo]()
$248
This Delta deal was found by Cheapflights users on 4/4. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
dv. 5/11:36 pm
ORD
- STL
2 stops9h 37m
Delta
dl. 5/44:41 pm
STL
- ORD
1 stop4h 44m
Delta
Deal found 4/4![Delta logo]()
$259
This United Airlines deal was found by Cheapflights users on 4/7. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
dv. 6/58:08 pm
ORD
- COU
Nonstop1h 51m
United Airlines
dg. 6/78:00 am
COU
- ORD
Nonstop1h 40m
United Airlines
Deal found 4/7![United Airlines logo]()
$259
This Southwest deal was found by Cheapflights users on 4/4. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
ds. 5/27:45 am
MDW
- STL
1 stop5h 50m
Southwest
ds. 5/95:15 am
STL
- MDW
2 stops6h 55m
Southwest
Deal found 4/4![Southwest logo]()
$216
This Contour deal was found by Cheapflights users on 4/7. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Contour is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
dv. 8/1412:10 pm
ORD
- CGI
Nonstop1h 40m
Contour
dt. 8/189:45 am
CGI
- ORD
Nonstop1h 45m
Contour
Deal found 4/7![Contour logo]()
$188
This American Airlines deal was found by Cheapflights users on 4/5. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
ds. 6/278:20 am
ORD
- COU
Nonstop1h 40m
American Airlines
dg. 6/2810:30 am
COU
- ORD
Nonstop1h 34m
American Airlines
Deal found 4/5![American Airlines logo]()
$254
This Delta deal was found by Cheapflights users on 4/5. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
dv. 6/121:16 pm
MDW
- STL
2 stops10h 07m
Delta
dt. 6/163:57 pm
STL
- MDW
1 stop6h 20m
Delta
Deal found 4/5![Delta logo]()
$262
This United Airlines deal was found by Cheapflights users on 4/5. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
dc. 4/228:09 pm
ORD
- SGF
Nonstop1h 55m
United Airlines
dl. 4/276:50 pm
SGF
- ORD
Nonstop1h 48m
United Airlines
Deal found 4/5![United Airlines logo]()
$264
This Southwest deal was found by Cheapflights users on 4/7. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
dt. 5/511:35 am
MDW
- STL
2 stops6h 20m
Southwest
dt. 5/121:15 pm
STL
- MDW
2 stops6h 20m
Southwest
Deal found 4/7![Southwest logo]()
$223
Last-minute flights from Chicago to MissouriDiscover last-minute flight deals from Chicago to Missouri. Data last updated abril 9, 2026 and is based on user searches.
Discover last-minute flight deals from Chicago to Missouri. Data last updated abril 9, 2026 and is based on user searches.
This Mytrip deal was found by Cheapflights users on 4/5. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Mytrip is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
dj. 4/2312:10 pm
ORD
- CGI
Nonstop1h 40m
Contour
dv. 4/249:45 am
CGI
- ORD
Nonstop1h 45m
Contour
Deal found 4/5![Contour logo]()
$119
This Mytrip deal was found by Cheapflights users on 4/7. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Mytrip is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
dj. 4/2312:10 pm
ORD
- CGI
Nonstop1h 40m
Contour
dg. 4/269:45 am
CGI
- ORD
Nonstop1h 45m
Contour
Deal found 4/7![Contour logo]()
$132
This Mytrip deal was found by Cheapflights users on 4/6. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Mytrip is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
dv. 4/2412:10 pm
ORD
- CGI
Nonstop1h 40m
Contour
dg. 4/269:45 am
CGI
- ORD
Nonstop1h 45m
Contour
Deal found 4/6![Contour logo]()
$122
This Contour deal was found by Cheapflights users on 4/6. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Contour is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
ds. 4/2512:10 pm
ORD
- CGI
Nonstop1h 40m
Contour
dt. 4/289:45 am
CGI
- ORD
Nonstop1h 45m
Contour
Deal found 4/6![Contour logo]()
$139
This Kiwi.com deal was found by Cheapflights users on 4/7. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
dt. 4/2811:28 am
ORD
- STL
1 stop19h 22m
Multiple Airlines
dv. 5/18:23 pm
STL
- ORD
2 stops19h 00m
Multiple Airlines
Deal found 4/7![Multiple Airlines logo]()
$190
This Southwest deal was found by Cheapflights users on 4/7. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
dj. 4/309:30 pm
MDW
- STL
Nonstop1h 15m
Southwest
dl. 5/47:20 am
STL
- MDW
Nonstop1h 10m
Southwest
Deal found 4/7![Southwest logo]()
$191
This American Airlines deal was found by Cheapflights users on 4/8. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
dj. 4/303:18 pm
ORD
- STL
Nonstop1h 23m
American Airlines
dl. 5/44:30 pm
STL
- ORD
Nonstop1h 40m
American Airlines
Deal found 4/8![American Airlines logo]()
$191
This Kiwi.com deal was found by Cheapflights users on 4/7. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
dj. 4/308:21 am
MDW
- STL
1 stop14h 58m
Frontier
dl. 5/48:23 pm
STL
- MDW
1 stop14h 46m
Frontier
Deal found 4/7![Frontier logo]()
$192
This Kiwi.com deal was found by Cheapflights users on 4/7. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
dj. 4/3011:28 am
ORD
- STL
2 stops11h 51m
Multiple Airlines
dl. 5/48:23 pm
STL
- ORD
1 stop11h 32m
Multiple Airlines
Deal found 4/7![Multiple Airlines logo]()
$193
This American Airlines deal was found by Cheapflights users on 4/6. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
dt. 5/511:15 am
ORD
- STL
1 stop5h 48m
American Airlines
dt. 5/128:55 am
STL
- ORD
Nonstop1h 28m
American Airlines
Deal found 4/6![American Airlines logo]()
$197
This Kiwi.com deal was found by Cheapflights users on 4/8. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
ds. 5/99:17 am
ORD
- STL
1 stop8h 47m
Multiple Airlines
ds. 5/165:27 pm
STL
- ORD
1 stop14h 28m
Multiple Airlines
Deal found 4/8![Multiple Airlines logo]()
$198
This American Airlines deal was found by Cheapflights users on 4/8. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
ds. 5/233:20 pm
ORD
- STL
Nonstop1h 32m
American Airlines
ds. 5/308:02 pm
STL
- ORD
Nonstop1h 43m
American Airlines
Deal found 4/8![American Airlines logo]()
$192
One-way flights from Chicago to MissouriSearch for one-way flight options from Chicago to Missouri. Find affordable one-way fares based on user searches. Data last updated abril 9, 2026.
Search for one-way flight options from Chicago to Missouri. Find affordable one-way fares based on user searches. Data last updated abril 9, 2026.
This Booking.com deal was found by Cheapflights users on 4/7. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Booking.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
dc. 5/63:55 pm
ORD
- CGI
Nonstop1h 40m
Contour
Deal found 4/7![Contour logo]()
$59
This Southwest deal was found by Cheapflights users on 4/6. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
dc. 5/61:55 pm
MDW
- STL
Nonstop1h 10m
Southwest
Deal found 4/6![Southwest logo]()
$59
This American Airlines deal was found by Cheapflights users on 4/8. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
dc. 5/610:30 pm
ORD
- STL
Nonstop1h 16m
American Airlines
Deal found 4/8![American Airlines logo]()
$59
This Kiwi.com deal was found by Cheapflights users on 4/6. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
dt. 4/2811:28 am
ORD
- STL
1 stop19h 22m
Multiple Airlines
Deal found 4/6![Multiple Airlines logo]()
$66
This Southwest deal was found by Cheapflights users on 4/6. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
dc. 5/62:40 pm
ORD
- STL
1 stop4h 35m
Southwest
Deal found 4/6![Southwest logo]()
$69
This Frontier deal was found by Cheapflights users on 4/5. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Frontier is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
dv. 5/84:52 pm
MDW
- STL
1 stop7h 29m
Frontier
Deal found 4/5![Frontier logo]()
$70
This Frontier deal was found by Cheapflights users on 4/7. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Frontier is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
ds. 5/165:30 pm
ORD
- STL
1 stop6h 51m
Frontier
Deal found 4/7![Frontier logo]()
$70
This Southwest deal was found by Cheapflights users on 4/6. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
dt. 4/2811:35 am
MDW
- STL
2 stops6h 20m
Southwest
Deal found 4/6![Southwest logo]()
$74
This Southwest deal was found by Cheapflights users on 4/6. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
dt. 5/55:55 am
ORD
- STL
2 stops7h 30m
Southwest
Deal found 4/6![Southwest logo]()
$74
This Kiwi.com deal was found by Cheapflights users on 4/4. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
dt. 5/56:00 am
MDW
- STL
1 stop26h 55m
Frontier
Deal found 4/4![Frontier logo]()
$76
This Kiwi.com deal was found by Cheapflights users on 4/5. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
dt. 5/57:15 am
ORD
- STL
1 stop25h 40m
Frontier
Deal found 4/5![Frontier logo]()
$76
This Delta deal was found by Cheapflights users on 4/5. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
dc. 5/66:00 am
MDW
- STL
1 stop5h 56m
Delta
Deal found 4/5![Delta logo]()
$79
Find flight deals from Chicago to Missouri
Keep the following information in mind while searching for Chicago to Missouri flight deals. Data was last updated abril 9, 2026.
Most accurate provider | FlightHub 3 stars |
|---|---|
Most trusted provider | FlightHub 3 stars |
Round-trip from | $119 (Mytrip) |
One-way from | $59 (Booking.com) |
Popular in | January |
Cheapest in | December |
Average price | $400 |
Good round-trip deal | $104 or less |
Good one-way deal | $166 or less |
Cheapflights Fare Finder
Customize your flight search to find flights from Chicago to Missouri that fit within your specific budget. Explore options based on user searches and filter the results based on your desired price range. Find flights that match your budget for a cost-effective journey. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated abril 9, 2026.
Use the filters below to find and compare flights from Chicago to Missouri that are best for you.
Fly from
Fly to
Route
Depart
Return
Cheapest round-trip
ChicagoCape Girardeau
ORD - CGI
ORDCGI
Chicago O'Hare Intl
dv. 6/12
12:10 pm-1:50 pm
Nonstop1h 40m
Cape Girardeau
dl. 6/15
9:45 am-11:30 am
Nonstop1h 45m
$121
ChicagoCape Girardeau
ORD - CGI
ORDCGI
Chicago O'Hare Intl
ds. 4/25
12:10 pm-1:50 pm
Nonstop1h 40m
Cape Girardeau
dt. 4/28
9:45 am-11:30 am
Nonstop1h 45m
$139
ChicagoCape Girardeau
ORD - CGI
ORDCGI
Chicago O'Hare Intl
dl. 4/20
12:10 pm-1:50 pm
Nonstop1h 40m
Cape Girardeau
dv. 4/24
9:45 am-11:30 am
Nonstop1h 45m
$139
ChicagoCape Girardeau
ORD - CGI
ORDCGI
Chicago O'Hare Intl
dc. 8/19
3:55 pm-5:35 pm
Nonstop1h 40m
Cape Girardeau
dl. 8/24
9:45 am-11:30 am
Nonstop1h 45m
$178
ChicagoCape Girardeau
ORD - CGI
ORDCGI
Chicago O'Hare Intl
ds. 8/15
3:55 pm-5:35 pm
Nonstop1h 40m
Cape Girardeau
dl. 8/24
9:45 am-11:30 am
Nonstop1h 45m
$178
ChicagoCape Girardeau
ORD - CGI
ORDCGI
Chicago O'Hare Intl
dl. 8/17
12:10 pm-1:50 pm
Nonstop1h 40m
Cape Girardeau
dj. 8/20
9:45 am-11:30 am
Nonstop1h 45m
$178
ChicagoCape Girardeau
ORD - CGI
ORDCGI
Chicago O'Hare Intl
dt. 8/18
12:10 pm-1:50 pm
Nonstop1h 40m
Cape Girardeau
ds. 8/22
1:30 pm-3:15 pm
Nonstop1h 45m
$178
ChicagoCape Girardeau
ORD - CGI
ORDCGI
Chicago O'Hare Intl
dv. 8/14
12:10 pm-1:50 pm
Nonstop1h 40m
Cape Girardeau
dt. 8/18
9:45 am-11:30 am
Nonstop1h 45m
$188
Quickest round-trip
ChicagoSt. Louis
MDW - STL
MDWSTL
Chicago Midway
dj. 4/30
9:30 pm-10:45 pm
Nonstop1h 15m
Lambert-St Louis
dl. 5/4
9:40 pm-10:45 pm
Nonstop1h 05m
$191
ChicagoSt. Louis
ORD - STL
ORDSTL
Chicago O'Hare Intl
dt. 5/5
11:15 am-5:03 pm
1 stop5h 48m
Lambert-St Louis
dt. 5/12
7:05 am-8:36 am
Nonstop1h 31m
$197
Showing 1-10 of 60 resultsSorted by cheapest first
Best time to book a flight from Chicago to Missouri
Have a flexible travel schedule? Discover the best time to fly to Missouri from Chicago with our price prediction graph.
ORD-CGI
ORD-STL
MDW-STL
ORD-MCI
MDW-SGF
Estimated round-trip price
Rates are based on past data. Find the cheapest month and day to book your flight based on your travel requirements, then search for cheap deals.
Cheapflights Insights
Everything you need to know about your flight from Chicago to Missouri
CHI-USMO
ORD-CGI
ORD-STL
MDW-STL
ORD-MCI
What is the cheapest month to book a flight from Chicago to Missouri?
Currently, August is the cheapest month in which you can book a flight from Chicago to Missouri (average of $77). Flying from Chicago to Missouri in May is currently the most expensive (average of $179). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.
What is the cheapest time of day to fly from CHI to MO?
Find hourly flight availability from Chicago to Missouri. Discover flight options and departure times throughout the day, allowing you to choose a departure time that suits your schedule. Data last updated abril 9, 2026.
It’s optimal to fly from Chicago to Missouri in the morning. By choosing this option you can save up to 18% on the cost of your flight, compared to a flight in the evening.
What is the cheapest day to fly from Chicago to Missouri?
Use this chart to determine the cheapest time to fly round-trip from Chicago to Missouri. Price data was last updated on April 4, 2026.
Travelers seeking maximum savings on their Chicago to Missouri flight should consider departing on Friday afternoons when fares are most often at their lowest. Saturday evenings flights should be avoided if possible as fares are typically the most expensive at this time.
Weekly flight availability from Chicago to Missouri
Explore weekly flight availability from Chicago to Missouri. Discover flights operating on different days of the week, giving you the flexibility to choose a travel day that best fits your plans. Compare info to find the most convenient option for your journey. Data last updated abril 9, 2026.
The most flights from CHI to USMO are scheduled on a Monday (80 on average). You will have fewer flight options on Saturday, which is when the least amount of flights are scheduled (50 on average).
How much does it cost to fly round-trip from Chicago to Missouri?
Reviews of airlines servicing Missouri
Get insights into the airlines that provide service to Missouri. Read reviews, discover amenities, and learn about the overall travel experience offered by airlines. Use this information to make informed decisions when choosing an airline for your flight to Missouri. Reviews last updated abril 9, 2026.
Get a feel of what it's like to fly with Southwest,Contour, andUnited Airlines from Chicago to Missouri by reading reviews from past customers. You can also see how each airline compares in terms of entertainment options, comfort, food, crew/service, and boarding process.
Entertainment
7.5
Food
7.0
Overall
8.0
Boarding
8.1
Comfort
8.0
Crew
8.6
Reviews
1 / 20
2.0
MediocreDominic,Mar 2026
MCO - SMF
Entertainment
7.5
Food
7.0
Overall
8.0
Boarding
8.1
Comfort
8.0
Crew
8.6
Reviews
1 / 20
2.0
MediocreDominic,Mar 2026
MCO - SMF
Entertainment
7.5
Food
7.0
Overall
8.0
Boarding
8.1
Comfort
8.0
Crew
8.6
Reviews
1 / 20
2.0
MediocreDominic,Mar 2026
MCO - SMF
Entertainment
7.5
Food
7.0
Overall
8.0
Boarding
8.1
Comfort
8.0
Crew
8.6
Reviews
1 / 20
2.0
MediocreDominic,Mar 2026
MCO - SMF
Entertainment
7.5
Food
7.0
Overall
8.0
Boarding
8.1
Comfort
8.0
Crew
8.6
Reviews
1 / 20
2.0
MediocreDominic,Mar 2026
MCO - SMF
Entertainment
7.5
Food
7.0
Overall
8.0
Boarding
8.1
Comfort
8.0
Crew
8.6
Reviews
1 / 20
2.0
MediocreDominic,Mar 2026
MCO - SMF
Related info for your journey
Find useful and relevant information for your journey from Chicago to Missouri. Access travel guides, tips, and recommendations to enhance your travel experience. Get information about local attractions, weather, transportation options, and more.
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Alternative routes for Chicago to Missouri
See prices for flight routes from nearby airports that may be better suited for you.
Complete your trip
Complete your trip to Missouri by adding a car rental and/or hotel reservation to your travel itinerary.
Search flights from Chicago to Missouri by cabin class
Find flights from Chicago to Missouri, based on your preferred cabin class, be it economy, premium economy, business, or first class.
Chicago and Missouri flights
Browse other Chicago and Missouri flight options. Last updated on abril 9, 2026.
Popular flight searches
Check out other popular destinations found by fellow travelers in 2026
Chicago to Missouri flights
Consider these flights traveling from Chicago to Missouri.
Top 5 airlines flying from Chicago to Missouri
Discover the top 5 airlines that operate flights from Chicago to Missouri. Compare their services, reliability, and customer satisfaction ratings to choose the airline that best suits your travel preferences and needs. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated abril 9, 2026.
| Airline | Cheapest | Average | Flexibility | On-time |
|---|---|---|---|---|
| Cheapest$77 | Average$359 | FlexibilityNo cancel fee | On-time63% | |
| Cheapest$104 | Average$164 | FlexibilityNo cancel fee | On-timeN/A | |
| Cheapest$124 | Average$305 | FlexibilityNo cancel fee | On-time71% | |
| Cheapest$151 | Average$352 | FlexibilityNo cancel fee | On-time69% | |
| Cheapest$156 | Average$227 | FlexibilityNo cancel fee | On-timeN/A |