$59+ Cheap flights from Chicago (CHI) to Missouri
This is the cheapest round-trip flight price found by a Cheapflights user in the last 72 hours by searching for a flight departing on 1/22. Fares are subject to change and may not be available on all flights or dates of travel.
CHI — STL
Dec 5 — Dec 121
Round-trip
1 adult, Economy
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Find cheap flights from Chicago to Missouri with Cheapflights
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Enter your travel information like dates, passengers, trip type (one-way or round trip), and preferred cabin class then click “Find deals”2. Select your favorite providers
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Cheapest flights from Chicago to MissouriExplore the most affordable flight options available from Chicago to Missouri. Find the lowest fares from popular airlines and budget airlines, with prices last updated on November 5, 2026.
Explore the most affordable flight options available from Chicago to Missouri. Find the lowest fares from popular airlines and budget airlines, with prices last updated on November 5, 2026.
This Mytrip deal was found by Cheapflights users on 10/31. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Mytrip is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 12/12:55 pm -
Nonstop1h 30m
Wed 12/212:30 pm -
Nonstop1h 45m
Deal found 10/31![Contour logo]()
$122
This Flightnetwork deal was found by Cheapflights users on 11/3. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Flightnetwork is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 12/202:55 pm -
Nonstop1h 30m
Sun 12/2712:30 pm -
Nonstop1h 45m
Deal found 11/3![Contour logo]()
$147
This Southwest deal was found by Cheapflights users on 11/3. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 12/211:30 am -
Nonstop1h 10m
Wed 12/94:40 pm -
Nonstop1h 10m
Deal found 11/3![Southwest logo]()
$154
This Delta deal was found by Cheapflights users on 11/3. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 12/31:41 pm -
1 stop3h 39m
Mon 12/72:17 pm -
1 stop3h 44m
Deal found 11/3![Delta logo]()
$157
This Delta deal was found by Cheapflights users on 11/3. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 11/252:44 pm -
1 stop5h 45m
Fri 11/274:39 pm -
1 stop3h 38m
Deal found 11/3![Delta logo]()
$157
This Mytrip deal was found by Cheapflights users on 11/4. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Mytrip is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 12/311:15 am -
Nonstop1h 35m
Mon 12/79:40 am -
Nonstop1h 55m
Deal found 11/4![Contour logo]()
$161
This Southwest deal was found by Cheapflights users on 11/3. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 12/38:00 am -
1 stop5h 40m
Mon 12/72:25 pm -
Nonstop1h 05m
Deal found 11/3![Southwest logo]()
$164
This FlightHub deal was found by Cheapflights users on 11/4. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure FlightHub is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 12/411:15 am -
Nonstop1h 35m
Sun 12/69:40 am -
Nonstop1h 55m
Deal found 11/4![Contour logo]()
$167
This Contour deal was found by Cheapflights users on 11/4. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Contour is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 11/1911:15 am -
Nonstop1h 35m
Mon 11/239:40 am -
Nonstop1h 55m
Deal found 11/4![Contour logo]()
$178
This Kissandfly.com deal was found by Cheapflights users on 11/3. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kissandfly.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 12/36:30 pm -
Nonstop1h 28m
Mon 12/712:02 pm -
1 stop9h 27m
Deal found 11/3![Frontier logo]()
$178
This Frontier deal was found by Cheapflights users on 10/31. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Frontier is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 11/186:08 am -
1 stop11h 34m
Sat 11/211:20 pm -
1 stop6h 27m
Deal found 10/31![Frontier logo]()
$179
This Frontier deal was found by Cheapflights users on 10/31. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Frontier is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 11/186:30 am -
1 stop8h 53m
Sat 11/216:05 pm -
1 stop6h 38m
Deal found 10/31![Frontier logo]()
$179
Best flights from Chicago to MissouriDiscover carefully curated flight deals from Chicago to Missouri that have cost, travel time, and layovers in mind to ensure you get the best travel experience. Data last updated November 5, 2026.
Discover carefully curated flight deals from Chicago to Missouri that have cost, travel time, and layovers in mind to ensure you get the best travel experience. Data last updated November 5, 2026.
This Mytrip deal was found by Cheapflights users on 10/31. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Mytrip is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 12/12:55 pm -
Nonstop1h 30m
Wed 12/212:30 pm -
Nonstop1h 45m
Deal found 10/31![Contour logo]()
$122
This Delta deal was found by Cheapflights users on 11/4. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 12/75:30 pm -
1 stop5h 56m
Thu 12/106:32 am -
1 stop6h 29m
Deal found 11/4![Delta logo]()
$157
This United Airlines deal was found by Cheapflights users on 11/3. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 12/310:52 am -
Nonstop1h 30m
Mon 12/71:18 pm -
Nonstop1h 29m
Deal found 11/3![United Airlines logo]()
$208
This Southwest deal was found by Cheapflights users on 11/3. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 12/196:55 pm -
2 stops5h 35m
Mon 1/41:55 pm -
1 stop3h 45m
Deal found 11/3![Southwest logo]()
$262
This Kiwi.com deal was found by Cheapflights users on 10/31. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 12/12:55 pm -
Nonstop1h 30m
Wed 12/25:10 pm -
1 stop14h 44m
Deal found 10/31![Multiple Airlines logo]()
$296
This American Airlines deal was found by Cheapflights users on 11/1. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 11/255:29 pm -
Nonstop1h 59m
Sun 11/298:03 pm -
Nonstop1h 55m
Deal found 11/1![American Airlines logo]()
$319
This FlightHub deal was found by Cheapflights users on 11/4. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure FlightHub is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 12/411:15 am -
Nonstop1h 35m
Sun 12/69:40 am -
Nonstop1h 55m
Deal found 11/4![Contour logo]()
$167
This Mytrip deal was found by Cheapflights users on 11/1. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Mytrip is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 11/206:20 am -
2 stops11h 20m
Mon 11/236:35 pm -
2 stops21h 22m
Deal found 11/1![Frontier logo]()
$379
This deal was found by Cheapflights users on 11/3. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 12/411:15 am -
Nonstop1h 35m
Sat 12/52:10 pm -
Nonstop1h 55m
Deal found 11/3![Contour logo]()
$178
This Contour deal was found by Cheapflights users on 11/4. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Contour is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 11/1911:15 am -
Nonstop1h 35m
Mon 11/239:40 am -
Nonstop1h 55m
Deal found 11/4![Contour logo]()
$178
This Delta deal was found by Cheapflights users on 11/1. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 11/229:59 am -
1 stop6h 32m
Tue 11/2410:20 am -
1 stop3h 39m
Deal found 11/1![Delta logo]()
$233
This Contour deal was found by Cheapflights users on 11/1. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Contour is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 11/1911:15 am -
Nonstop1h 35m
Thu 11/269:40 am -
Nonstop1h 55m
Deal found 11/1![Contour logo]()
$198
This United Airlines deal was found by Cheapflights users on 11/4. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 11/253:30 pm -
Nonstop1h 29m
Sat 11/286:50 pm -
Nonstop1h 29m
Deal found 11/4![United Airlines logo]()
$273
This KAYAK deal was found by Cheapflights users on 11/3. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure KAYAK is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 12/911:39 am -
1 stop5h 41m
Thu 12/1010:14 am -
1 stop3h 42m
Deal found 11/3![Delta logo]()
$253
This Contour deal was found by Cheapflights users on 11/3. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Contour is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 11/1811:15 am -
Nonstop1h 35m
Sun 11/229:40 am -
Nonstop1h 55m
Deal found 11/3![Contour logo]()
$198
This Southwest deal was found by Cheapflights users on 11/1. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 11/255:00 pm -
2 stops6h 30m
Fri 11/278:35 pm -
Nonstop1h 25m
Deal found 11/1![Southwest logo]()
$291
This United Airlines deal was found by Cheapflights users on 11/4. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 11/267:59 am -
Nonstop2h 00m
Mon 11/306:01 am -
Nonstop1h 58m
Deal found 11/4![United Airlines logo]()
$281
This Delta deal was found by Cheapflights users on 11/4. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 1/69:58 am -
1 stop4h 39m
Tue 1/123:32 pm -
1 stop6h 04m
Deal found 11/4![Delta logo]()
$257
This Southwest deal was found by Cheapflights users on 11/3. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 11/249:50 am -
1 stop3h 55m
Fri 11/271:55 pm -
1 stop3h 45m
Deal found 11/3![Southwest logo]()
$296
This Kiwi.com deal was found by Cheapflights users on 11/3. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 12/202:55 pm -
Nonstop1h 30m
Sun 12/275:10 pm -
1 stop14h 32m
Deal found 11/3![Multiple Airlines logo]()
$332
This American Airlines deal was found by Cheapflights users on 11/4. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 11/224:27 pm -
Nonstop1h 36m
Mon 11/306:28 pm -
Nonstop1h 46m
Deal found 11/4![American Airlines logo]()
$334
This United Airlines deal was found by Cheapflights users on 11/4. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 11/227:59 am -
Nonstop2h 00m
Thu 11/266:01 am -
Nonstop1h 58m
Deal found 11/4![United Airlines logo]()
$291
This Southwest deal was found by Cheapflights users on 11/1. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 12/116:50 am -
Nonstop1h 40m
Sun 12/135:35 am -
Nonstop1h 25m
Deal found 11/1![Southwest logo]()
$297
This Contour deal was found by Cheapflights users on 11/3. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Contour is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 12/1911:15 am -
Nonstop1h 35m
Sat 12/262:10 pm -
Nonstop1h 55m
Deal found 11/3![Contour logo]()
$230
This United Airlines deal was found by Cheapflights users on 11/1. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 12/119:25 pm -
Nonstop1h 42m
Sun 12/1311:27 am -
Nonstop1h 48m
Deal found 11/1![United Airlines logo]()
$297
This Delta deal was found by Cheapflights users on 11/3. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 12/89:37 am -
1 stop3h 53m
Fri 12/112:17 pm -
1 stop3h 44m
Deal found 11/3![Delta logo]()
$298
This Mytrip deal was found by Cheapflights users on 11/4. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Mytrip is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 12/42:55 pm -
3 stops20h 02m
Fri 12/117:54 pm -
2 stops26h 06m
Deal found 11/4![Multiple Airlines logo]()
$363
This Southwest deal was found by Cheapflights users on 11/2. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 11/3012:50 pm -
Nonstop1h 10m
Mon 12/74:40 pm -
Nonstop1h 10m
Deal found 11/2![Southwest logo]()
$303
This American Airlines deal was found by Cheapflights users on 11/1. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 11/108:40 pm -
Nonstop1h 35m
Tue 11/176:15 am -
Nonstop1h 45m
Deal found 11/1![American Airlines logo]()
$369
This Contour deal was found by Cheapflights users on 11/1. Clicking the “Pick Dates ” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Contour is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 1/1111:15 am -
Nonstop1h 35m
Tue 1/129:40 am -
Nonstop1h 55m
Deal found 11/1![Contour logo]()
$238
Last-minute flights from Chicago to MissouriDiscover last-minute flight deals from Chicago to Missouri. Data last updated November 5, 2026 and is based on user searches.
Discover last-minute flight deals from Chicago to Missouri. Data last updated November 5, 2026 and is based on user searches.
This Frontier deal was found by Cheapflights users on 10/31. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Frontier is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 11/186:08 am -
1 stop11h 34m
Sat 11/211:20 pm -
1 stop6h 27m
Deal found 10/31![Frontier logo]()
$179
This Frontier deal was found by Cheapflights users on 10/31. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Frontier is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 11/186:30 am -
1 stop8h 53m
Sat 11/216:05 pm -
1 stop6h 38m
Deal found 10/31![Frontier logo]()
$179
This Contour deal was found by Cheapflights users on 11/4. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Contour is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 11/1911:15 am -
Nonstop1h 35m
Mon 11/239:40 am -
Nonstop1h 55m
Deal found 11/4![Contour logo]()
$178
This Delta deal was found by Cheapflights users on 11/3. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 11/252:44 pm -
1 stop5h 45m
Fri 11/274:39 pm -
1 stop3h 38m
Deal found 11/3![Delta logo]()
$157
This Mytrip deal was found by Cheapflights users on 10/31. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Mytrip is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 12/12:55 pm -
Nonstop1h 30m
Wed 12/212:30 pm -
Nonstop1h 45m
Deal found 10/31![Contour logo]()
$122
This Southwest deal was found by Cheapflights users on 11/3. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 12/211:30 am -
Nonstop1h 10m
Wed 12/94:40 pm -
Nonstop1h 10m
Deal found 11/3![Southwest logo]()
$154
This Delta deal was found by Cheapflights users on 11/3. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 12/31:41 pm -
1 stop3h 39m
Mon 12/72:17 pm -
1 stop3h 44m
Deal found 11/3![Delta logo]()
$157
This Mytrip deal was found by Cheapflights users on 11/4. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Mytrip is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 12/311:15 am -
Nonstop1h 35m
Mon 12/79:40 am -
Nonstop1h 55m
Deal found 11/4![Contour logo]()
$161
This Southwest deal was found by Cheapflights users on 11/3. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 12/38:00 am -
1 stop5h 40m
Mon 12/72:25 pm -
Nonstop1h 05m
Deal found 11/3![Southwest logo]()
$164
This Kissandfly.com deal was found by Cheapflights users on 11/3. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kissandfly.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 12/36:30 pm -
Nonstop1h 28m
Mon 12/712:02 pm -
1 stop9h 27m
Deal found 11/3![Frontier logo]()
$178
This FlightHub deal was found by Cheapflights users on 11/4. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure FlightHub is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 12/411:15 am -
Nonstop1h 35m
Sun 12/69:40 am -
Nonstop1h 55m
Deal found 11/4![Contour logo]()
$167
This Flightnetwork deal was found by Cheapflights users on 11/3. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Flightnetwork is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 12/202:55 pm -
Nonstop1h 30m
Sun 12/2712:30 pm -
Nonstop1h 45m
Deal found 11/3![Contour logo]()
$147
One-way flights from Chicago to MissouriSearch for one-way flight options from Chicago to Missouri. Find affordable one-way fares based on user searches. Data last updated November 5, 2026.
Search for one-way flight options from Chicago to Missouri. Find affordable one-way fares based on user searches. Data last updated November 5, 2026.
This Southwest deal was found by Cheapflights users on 11/3. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 11/248:00 am -
Nonstop1h 25m
Wed 12/3112:00 am -
Nonstop0h 00m
Deal found 11/3![Southwest logo]()
$59
This Frontier deal was found by Cheapflights users on 11/2. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Frontier is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 12/315:47 pm -
1 stop6h 54m
Wed 12/3112:00 am -
Nonstop0h 00m
Deal found 11/2![Frontier logo]()
$59
This Frontier deal was found by Cheapflights users on 11/2. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Frontier is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 12/21:19 pm -
1 stop6h 52m
Wed 12/3112:00 am -
Nonstop0h 00m
Deal found 11/2![Frontier logo]()
$60
This Southwest deal was found by Cheapflights users on 11/2. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 12/110:05 am -
1 stop3h 15m
Wed 12/3112:00 am -
Nonstop0h 00m
Deal found 11/2![Southwest logo]()
$69
This CheapOair deal was found by Cheapflights users on 11/3. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure CheapOair is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 11/248:42 pm -
1 stop15h 43m
Wed 12/3112:00 am -
Nonstop0h 00m
Deal found 11/3![Frontier logo]()
$70
This CheapOair deal was found by Cheapflights users on 11/2. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure CheapOair is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 12/15:35 am -
1 stop14h 32m
Wed 12/3112:00 am -
Nonstop0h 00m
Deal found 11/2![Frontier logo]()
$70
This Delta deal was found by Cheapflights users on 11/3. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 11/2612:05 pm -
1 stop4h 30m
Wed 12/3112:00 am -
Nonstop0h 00m
Deal found 11/3![Delta logo]()
$79
This Delta deal was found by Cheapflights users on 11/3. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 1/139:58 am -
1 stop4h 40m
Wed 12/3112:00 am -
Nonstop0h 00m
Deal found 11/3![Delta logo]()
$79
This deal was found by Cheapflights users on 11/3. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 12/511:15 am -
Nonstop1h 35m
Wed 12/3112:00 am -
Nonstop0h 00m
Deal found 11/3![Contour logo]()
$89
This Super.com deal was found by Cheapflights users on 10/31. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Super.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 12/36:21 am -
1 stop8h 20m
Wed 12/3112:00 am -
Nonstop0h 00m
Deal found 10/31![Frontier logo]()
$97
This Kiwi.com deal was found by Cheapflights users on 11/1. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 12/17:00 am -
1 stop12h 33m
Wed 12/3112:00 am -
Nonstop0h 00m
Deal found 11/1![Frontier logo]()
$101
This Kiwi.com deal was found by Cheapflights users on 11/2. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 12/77:25 am -
1 stop12h 10m
Wed 12/3112:00 am -
Nonstop0h 00m
Deal found 11/2![Frontier logo]()
$102
Find flight deals from Chicago to Missouri
Keep the following information in mind while searching for Chicago to Missouri flight deals. Data was last updated November 5, 2026.
Most accurate provider | FlightHub 3 stars |
|---|---|
Most trusted provider | FlightHub 3 stars |
Round-trip from | $122 (Mytrip) |
One-way from | $59 (Southwest) |
Popular in | April |
Cheapest in | December |
Average price | $279 |
Good round-trip deal | $154 or less |
Good one-way deal | $130 or less |
Cheapflights Fare Finder
Customize your flight search to find flights from Chicago to Missouri that fit within your specific budget. Explore options based on user searches and filter the results based on your desired price range. Find flights that match your budget for a cost-effective journey. Over the last 7 days, Cheapflights users made 7,457,451 searches. Data last updated November 5, 2026.
Use the filters below to find and compare flights from Chicago to Missouri that are best for you.
Fly from
Fly to
Route
Depart
Return
Cheapest round-trip
Quickest round-trip
ChicagoSt. Louis
MDW Chicago Midway - STL Lambert-St Louis
MDWSTL
Chicago Midway
Fri 1/22
3:25 pm-4:35 pm
Nonstop1h 10m
Lambert-St Louis
Wed 12/31
12:00 am-12:00 am
Nonstop0h 00m
$59
ChicagoSt. Louis
ORD Chicago O'Hare Intl - STL Lambert-St Louis
ORDSTL
Chicago O'Hare Intl
Wed 11/25
3:30 pm-4:59 pm
Nonstop1h 29m
Lambert-St Louis
Wed 12/31
12:00 am-12:00 am
Nonstop0h 00m
$59
ChicagoSt. Louis
MDW Chicago Midway - STL Lambert-St Louis
MDWSTL
Chicago Midway
Wed 12/2
8:10 am-1:20 pm
1 stop5h 10m
Lambert-St Louis
Wed 12/31
12:00 am-12:00 am
Nonstop0h 00m
$69
ChicagoSt. Louis
MDW Chicago Midway - STL Lambert-St Louis
MDWSTL
Chicago Midway
Fri 12/11
10:20 am-1:45 pm
1 stop3h 25m
Lambert-St Louis
Wed 12/31
12:00 am-12:00 am
Nonstop0h 00m
$69
ChicagoSt. Louis
MDW Chicago Midway - STL Lambert-St Louis
MDWSTL
Chicago Midway
Sat 12/5
5:50 am-1:40 pm
1 stop7h 50m
Lambert-St Louis
Wed 12/31
12:00 am-12:00 am
Nonstop0h 00m
$69
ChicagoSt. Louis
ORD Chicago O'Hare Intl - STL Lambert-St Louis
ORDSTL
Chicago O'Hare Intl
Mon 1/25
3:36 pm-10:45 pm
1 stop7h 09m
Lambert-St Louis
Wed 12/31
12:00 am-12:00 am
Nonstop0h 00m
$79
ChicagoSt. Louis
ORD Chicago O'Hare Intl - STL Lambert-St Louis
ORDSTL
Chicago O'Hare Intl
Sat 11/21
5:42 pm-11:22 pm
1 stop5h 40m
Lambert-St Louis
Wed 12/31
12:00 am-12:00 am
Nonstop0h 00m
$79
ChicagoSt. Louis
ORD Chicago O'Hare Intl - STL Lambert-St Louis
ORDSTL
Chicago O'Hare Intl
Wed 12/23
10:30 am-5:26 pm
1 stop6h 56m
Lambert-St Louis
Wed 12/31
12:00 am-12:00 am
Nonstop0h 00m
$79
ChicagoSt. Louis
ORD Chicago O'Hare Intl - STL Lambert-St Louis
ORDSTL
Chicago O'Hare Intl
Tue 12/1
7:05 am-1:30 pm
1 stop6h 25m
Lambert-St Louis
Wed 12/31
12:00 am-12:00 am
Nonstop0h 00m
$79
ChicagoSt. Louis
ORD Chicago O'Hare Intl - STL Lambert-St Louis
ORDSTL
Chicago O'Hare Intl
Sat 12/5
2:41 pm-8:32 pm
1 stop5h 51m
Lambert-St Louis
Wed 12/31
12:00 am-12:00 am
Nonstop0h 00m
$79
Showing 1-10 of 60 resultsSorted by cheapest first
Best time to book a flight from Chicago to Missouri
Have a flexible travel schedule? Discover the best time to fly to Missouri from Chicago with our price prediction graph.
ORD-IRK
MDW-STL
ORD-STL
ORD-CGI
ORD-COU
Estimated round-trip price
Rates are based on past data. Find the cheapest month and day to book your flight based on your travel requirements, then search for cheap deals.
Cheapflights Insights
Everything you need to know about your flight from Chicago to Missouri
CHI-USMO
ORD-IRK
MDW-STL
ORD-STL
ORD-CGI
What is the cheapest month to book a flight from Chicago to Missouri?
Currently, December is the cheapest month in which you can book a flight from Chicago to Missouri (average of $311). Flying from Chicago to Missouri in June is currently the most expensive (average of $457). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.
What is the cheapest time of day to fly from CHI to MO?
Find hourly flight availability from Chicago to Missouri. Discover flight options and departure times throughout the day, allowing you to choose a departure time that suits your schedule. Data last updated November 5, 2026.
It’s optimal to fly from Chicago to Missouri in the morning. By choosing this option you can save up to 11% on the cost of your flight, compared to a flight in the evening.
Weekly flight availability from Chicago to Missouri
Explore weekly flight availability from Chicago to Missouri. Discover flights operating on different days of the week, giving you the flexibility to choose a travel day that best fits your plans. Compare info to find the most convenient option for your journey. Data last updated November 5, 2026.
The most flights from CHI to USMO are scheduled on a Wednesday (71 on average). You will have fewer flight options on Saturday, which is when the least amount of flights are scheduled (31 on average).
How much does it cost to fly round-trip from Chicago to Missouri?
Airfare is below average for this route at the moment.
Chicago to Missouri flights typically cost between $239 and $508 in December.The cheapest round-trip price found within the last 5 days was $154 on Southwest (Dec 2-Dec 9).
How far ahead should I book a flight from Chicago to Missouri?
To ensure you get the cheapest price possible for a flight from Chicago to Missouri, you should look to book at least 81 days in advance of your intended travel date. The price of your flight may increase if you delay and leave booking until a week or so before departure.
What is the cheapest day to fly from Chicago to Missouri?
Use this chart to determine the cheapest time to fly round-trip from Chicago to Missouri. Price data was last updated on October 31, 2026.
Travelers seeking maximum savings on their Chicago to Missouri flight should consider departing on Saturday mornings when fares are most often at their lowest. Sunday evenings flights should be avoided if possible as fares are typically the most expensive at this time.
Reviews of airlines servicing Missouri
Get insights into the airlines that provide service to Missouri. Read reviews, discover amenities, and learn about the overall travel experience offered by airlines. Use this information to make informed decisions when choosing an airline for your flight to Missouri. Reviews last updated November 5, 2026.
Get a feel of what it's like to fly with Southwest,Contour, andUnited Airlines from Chicago to Missouri by reading reviews from past customers. You can also see how each airline compares in terms of entertainment options, comfort, food, crew/service, and boarding process.
Boarding
8.1
Comfort
8.0
Overall
8.0
Crew
8.6
Food
7.0
Entertainment
7.5
Reviews
1 / 20
10.0
ExcellentCourtney,Sep 2026
DEN - STL
Boarding
8.1
Comfort
8.0
Overall
8.0
Crew
8.6
Food
7.0
Entertainment
7.5
Reviews
1 / 20
10.0
ExcellentCourtney,Sep 2026
DEN - STL
Boarding
8.1
Comfort
8.0
Overall
8.0
Crew
8.6
Food
7.0
Entertainment
7.5
Reviews
1 / 20
10.0
ExcellentCourtney,Sep 2026
DEN - STL
Boarding
8.1
Comfort
8.0
Overall
8.0
Crew
8.6
Food
7.0
Entertainment
7.5
Reviews
1 / 20
10.0
ExcellentCourtney,Sep 2026
DEN - STL
Boarding
8.1
Comfort
8.0
Overall
8.0
Crew
8.6
Food
7.0
Entertainment
7.5
Reviews
1 / 20
10.0
ExcellentCourtney,Sep 2026
DEN - STL
Boarding
8.1
Comfort
8.0
Overall
8.0
Crew
8.6
Food
7.0
Entertainment
7.5
Reviews
1 / 20
10.0
ExcellentCourtney,Sep 2026
DEN - STL
Related info for your journey
Find useful and relevant information for your journey from Chicago to Missouri. Access travel guides, tips, and recommendations to enhance your travel experience. Get information about local attractions, weather, transportation options, and more.
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Alternative routes for Chicago to Missouri
See prices for flight routes from nearby airports that may be better suited for you.
Complete your trip
Complete your trip to Missouri by adding a car rental and/or hotel reservation to your travel itinerary.
Search flights from Chicago to Missouri by cabin class
Find flights from Chicago to Missouri, based on your preferred cabin class, be it economy, premium economy, business, or first class.
Chicago and Missouri flights
Browse other Chicago and Missouri flight options. Last updated on November 5, 2026.
Popular flight searches
Check out other popular destinations found by fellow travelers in 2026
Chicago to Missouri flights
Consider these flights traveling from Chicago to Missouri.
Top 4 airlines flying from Chicago to Missouri
Discover the top 4 airlines that operate flights from Chicago to Missouri. Compare their services, reliability, and customer satisfaction ratings to choose the airline that best suits your travel preferences and needs. Over the last 7 days, Cheapflights users made 7,457,451 searches. Data last updated November 5, 2026.
| Airline | Cheapest | Average | Flexibility | On-time |
|---|---|---|---|---|
| Cheapest$92 | Average$155 | FlexibilityNo cancel fee | On-timeN/A | |
| Cheapest$151 | Average$345 | FlexibilityNo cancel fee | On-time71% | |
| Cheapest$178 | Average$412 | FlexibilityNo cancel fee | On-time69% | |
| Cheapest$187 | Average$489 | FlexibilityNo cancel fee | On-time63% |