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$60+ Cheap flights from Chicago (CHI) to Missouri

This is the cheapest one-way flight price found by a Cheapflights user in the last 72 hours by searching for a flight departing on 2/25. Fares are subject to change and may not be available on all flights or dates of travel.
CHI — STL
Feb 23 — Mar 21
Mon 2/23
Mon 3/2
1 adult, Economy
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Cheap flight deals from Chicago to Missouri

Cheapest flights from Chicago to Missouri
Explore the most affordable flight options available from Chicago to Missouri. Find the lowest fares from popular airlines and budget airlines, with prices last updated on January 24, 2026.

This Mytrip deal was found by Cheapflights users on 1/23. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Mytrip is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 2/711:50 am
ORD
-
CGI
Nonstop1h 35m
Contour
Wed 2/119:30 am
CGI
-
ORD
Nonstop1h 40m
Contour
Deal found 1/23$123
This Booking.com deal was found by Cheapflights users on 1/22. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Booking.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 3/811:50 am
ORD
-
CGI
Nonstop1h 40m
Contour
Sun 3/159:25 am
CGI
-
ORD
Nonstop1h 45m
Contour
Deal found 1/22$125
This Contour deal was found by Cheapflights users on 1/23. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Contour is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 2/2711:50 am
ORD
-
CGI
Nonstop1h 35m
Contour
Mon 3/29:25 am
CGI
-
ORD
Nonstop1h 45m
Contour
Deal found 1/23$139
This Kiwi.com deal was found by Cheapflights users on 1/21. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 2/2012:53 pm
ORD
-
STL
1 stop25h 03m
Frontier
Fri 2/278:22 pm
STL
-
ORD
1 stop14h 29m
Frontier
Deal found 1/21$145
This Kiwi.com deal was found by Cheapflights users on 1/23. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 2/52:42 pm
ORD
-
STL
1 stop16h 09m
Frontier
Mon 2/98:22 pm
STL
-
ORD
1 stop14h 29m
Frontier
Deal found 1/23$151
This Kiwi.com deal was found by Cheapflights users on 1/22. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 1/292:42 pm
ORD
-
STL
1 stop16h 09m
Frontier
Fri 1/308:22 pm
STL
-
ORD
1 stop26h 22m
Frontier
Deal found 1/22$154
This Kiwi.com deal was found by Cheapflights users on 1/23. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 1/305:01 pm
MDW
-
STL
1 stop13h 50m
Frontier
Fri 2/68:22 pm
STL
-
MDW
1 stop12h 21m
Frontier
Deal found 1/23$156
This Kiwi.com deal was found by Cheapflights users on 1/22. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 2/194:42 pm
ORD
-
STL
1 stop14h 09m
Frontier
Thu 2/2610:11 pm
STL
-
ORD
1 stop19h 15m
Frontier
Deal found 1/22$156
This Kiwi.com deal was found by Cheapflights users on 1/22. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 1/306:20 am
MDW
-
STL
1 stop24h 31m
Frontier
Mon 2/28:22 pm
STL
-
MDW
1 stop15h 43m
Frontier
Deal found 1/22$158
This Kiwi.com deal was found by Cheapflights users on 1/22. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 2/52:42 pm
ORD
-
STL
1 stop16h 09m
Frontier
Sat 2/78:22 pm
STL
-
ORD
1 stop17h 15m
Frontier
Deal found 1/22$158
This Frontier deal was found by Cheapflights users on 1/24. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Frontier is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 2/236:00 am
ORD
-
STL
1 stop14h 02m
Frontier
Mon 3/23:49 pm
STL
-
ORD
1 stop7h 26m
Frontier
Deal found 1/24$160
This Kiwi.com deal was found by Cheapflights users on 1/22. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 2/38:10 am
ORD
-
STL
1 stop22h 41m
Multiple Airlines
Wed 2/48:22 pm
STL
-
ORD
2 stops15h 00m
Multiple Airlines
Deal found 1/22$167

Find flight deals from Chicago to Missouri

Keep the following information in mind while searching for Chicago to Missouri flight deals. Data was last updated January 24, 2026.

Most accurate provider

FlightHub
3 stars

Most trusted provider

Expedia
3 stars

Round-trip from

$123
(Mytrip)

One-way from

$60
(Kiwi.com)

Popular in

January

Cheapest in

December

Average price

$551

Good round-trip deal

$108 or less

Good one-way deal

$54 or less
Provider with most accurate pricing for Chicago (CHI)-Lambert-St Louis flight deals.
Search Deals
Provider most trusted by Cheapflights users for Chicago (CHI)-Lambert-St Louis flights.
Search Deals
From Chicago (CHI) to Missouri
Search Deals
One-way flight from Chicago (CHI) to Missouri
Search Deals
Highest demand for flights based on searches. 12% potential increase in price ($43 potential increase over avg. RT price).
Search Deals
Cheapest flight prices on average. 7% potential price decrease ($23 potential savings vs. average RT price).
Search Deals
Average for round-trip flights in January 2026
Search Deals
Price to beat on a round-trip flight from Chicago (CHI) to Missouri.
Search Deals
Price to beat on a one-way flight from Chicago (CHI) to Missouri.
Search Deals

Cheapflights Fare Finder

 
Customize your flight search to find flights from Chicago to Missouri that fit within your specific budget. Explore options based on user searches and filter the results based on your desired price range. Find flights that match your budget for a cost-effective journey. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated January 24, 2026.
Use the filters below to find and compare flights from Chicago to Missouri that are best for you.

Fly from

Chicago

Fly to

Missouri

Route

Depart

Return

Price

ChicagoCape Girardeau

ORD - CGI

ORDCGI

Chicago O'Hare Intl

Sat 2/7

11:50 am-1:25 pm

Nonstop1h 35m

Cape Girardeau

Wed 2/11

9:30 am-11:10 am

Nonstop1h 40m

$123

ChicagoCape Girardeau

ORD - CGI

ORDCGI

Chicago O'Hare Intl

Sun 3/8

11:50 am-1:30 pm

Nonstop1h 40m

Cape Girardeau

Sun 3/15

9:25 am-11:10 am

Nonstop1h 45m

$125

ChicagoCape Girardeau

ORD - CGI

ORDCGI

Chicago O'Hare Intl

Fri 2/27

11:50 am-1:25 pm

Nonstop1h 35m

Cape Girardeau

Mon 3/2

9:25 am-11:10 am

Nonstop1h 45m

$139

ChicagoSt. Louis

MDW - STL

MDWSTL

Chicago Midway

Mon 2/23

8:15 am-9:35 am

Nonstop1h 20m

Lambert-St Louis

Mon 3/2

4:30 pm-5:40 pm

Nonstop1h 10m

$171

ChicagoColumbia

ORD - COU

ORDCOU

Chicago O'Hare Intl

Fri 2/13

9:00 am-10:33 am

Nonstop1h 33m

Columbia Regional

Sun 2/15

11:15 am-12:45 pm

Nonstop1h 30m

$179

ChicagoColumbia

ORD - COU

ORDCOU

Chicago O'Hare Intl

Fri 4/3

4:30 pm-6:00 pm

Nonstop1h 30m

Columbia Regional

Sat 4/4

6:50 pm-8:25 pm

Nonstop1h 35m

$179

ChicagoColumbia

ORD - COU

ORDCOU

Chicago O'Hare Intl

Fri 4/3

9:15 am-10:55 am

Nonstop1h 40m

Columbia Regional

Sun 4/5

11:30 am-1:00 pm

Nonstop1h 30m

$179

ChicagoColumbia

ORD - COU

ORDCOU

Chicago O'Hare Intl

Thu 2/12

8:00 am-9:28 am

Nonstop1h 28m

Columbia Regional

Mon 2/16

6:35 pm-8:10 pm

Nonstop1h 35m

$179

ChicagoColumbia

ORD - COU

ORDCOU

Chicago O'Hare Intl

Fri 2/20

9:00 am-10:33 am

Nonstop1h 33m

Columbia Regional

Sun 2/22

11:15 am-12:45 pm

Nonstop1h 30m

$179

ChicagoColumbia

ORD - COU

ORDCOU

Chicago O'Hare Intl

Sat 4/18

1:16 pm-2:48 pm

Nonstop1h 32m

Columbia Regional

Sun 4/19

11:30 am-1:00 pm

Nonstop1h 30m

$179

Flights are sorted by cheapest round-trip flights first.

Deals found on 1/22

Showing 1-10 of 60 results
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Best time to book a flight from Chicago to Missouri

Have a flexible travel schedule? Discover the best time to fly to Missouri from Chicago with our price prediction graph.
Estimated round-trip price
Rates are based on past data. Find the cheapest month and day to book your flight based on your travel requirements, then search for cheap deals.

Cheapflights Insights

Everything you need to know about your flight from Chicago to Missouri

What is the cheapest month to book a flight from Chicago to Missouri?

Currently, August is the cheapest month in which you can book a flight from Chicago to Missouri (average of $77). Flying from Chicago to Missouri in February is currently the most expensive (average of $169). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.

What is the cheapest time of day to fly from CHI to MO?

Find hourly flight availability from Chicago to Missouri. Discover flight options and departure times throughout the day, allowing you to choose a departure time that suits your schedule. Data last updated January 24, 2026.

It’s optimal to fly from Chicago to Missouri in the morning. By choosing this option you can save up to 11% on the cost of your flight, compared to a flight at noon.

What is the cheapest day to fly from Chicago to Missouri?

Use this chart to determine the cheapest time to fly round-trip from Chicago to Missouri. Price data was last updated on January 17, 2026.

Travelers seeking maximum savings on their Chicago to Missouri flight should consider departing on Friday afternoons when fares are most often at their lowest. Saturday afternoons flights should be avoided if possible as fares are typically the most expensive at this time.

Weekly flight availability from Chicago to Missouri

Explore weekly flight availability from Chicago to Missouri. Discover flights operating on different days of the week, giving you the flexibility to choose a travel day that best fits your plans. Compare info to find the most convenient option for your journey. Data last updated January 24, 2026.

The most flights from CHI to USMO are scheduled on a Friday (56 on average). You will have fewer flight options on Saturday, which is when the least amount of flights are scheduled (27 on average).

How much does it cost to fly round-trip from Chicago to Missouri?

Reviews of airlines servicing Missouri

Get insights into the airlines that provide service to Missouri. Read reviews, discover amenities, and learn about the overall travel experience offered by airlines. Use this information to make informed decisions when choosing an airline for your flight to Missouri. Reviews last updated January 24, 2026.
Get a feel of what it's like to fly with Southwest, Contour, and United Airlines from Chicago to Missouri by reading reviews from past customers. You can also see how each airline compares in terms of entertainment options, comfort, food, crew/service, and boarding process.
Southwest
8.0
Very good
4,269 reviews

Comfort

8.0

Entertainment

7.5

Overall

8.0

Boarding

8.1

Crew

8.6

Food

7.0

Reviews

1 / 20
2.0
Mediocre

Thomas,Dec 2025

SEA - DEN

Plane two hours late in leaving 1:00 pm west coat time got home next day at 2:45am most car rental places are closed and don’t open till 5am
Southwest
8.0
Very good
4,269 reviews
Southwest
8.0
Very good
4,269 reviews

Comfort

8.0

Entertainment

7.5

Overall

8.0

Boarding

8.1

Crew

8.6

Food

7.0

Reviews

1 / 20
2.0
Mediocre

Thomas,Dec 2025

SEA - DEN

Plane two hours late in leaving 1:00 pm west coat time got home next day at 2:45am most car rental places are closed and don’t open till 5am
Contour
7.6
Good
42 reviews
Southwest
8.0
Very good
4,269 reviews

Comfort

8.0

Entertainment

7.5

Overall

8.0

Boarding

8.1

Crew

8.6

Food

7.0

Reviews

1 / 20
2.0
Mediocre

Thomas,Dec 2025

SEA - DEN

Plane two hours late in leaving 1:00 pm west coat time got home next day at 2:45am most car rental places are closed and don’t open till 5am
United Airlines
7.4
Good
9,200 reviews
Southwest
8.0
Very good
4,269 reviews

Comfort

8.0

Entertainment

7.5

Overall

8.0

Boarding

8.1

Crew

8.6

Food

7.0

Reviews

1 / 20
2.0
Mediocre

Thomas,Dec 2025

SEA - DEN

Plane two hours late in leaving 1:00 pm west coat time got home next day at 2:45am most car rental places are closed and don’t open till 5am
American Airlines
7.2
Good
11,195 reviews
Southwest
8.0
Very good
4,269 reviews

Comfort

8.0

Entertainment

7.5

Overall

8.0

Boarding

8.1

Crew

8.6

Food

7.0

Reviews

1 / 20
2.0
Mediocre

Thomas,Dec 2025

SEA - DEN

Plane two hours late in leaving 1:00 pm west coat time got home next day at 2:45am most car rental places are closed and don’t open till 5am
Southern / Mokulele
6.5
Okay
27 reviews
Southwest
8.0
Very good
4,269 reviews

Comfort

8.0

Entertainment

7.5

Overall

8.0

Boarding

8.1

Crew

8.6

Food

7.0

Reviews

1 / 20
2.0
Mediocre

Thomas,Dec 2025

SEA - DEN

Plane two hours late in leaving 1:00 pm west coat time got home next day at 2:45am most car rental places are closed and don’t open till 5am

Related info for your journey

Find useful and relevant information for your journey from Chicago to Missouri. Access travel guides, tips, and recommendations to enhance your travel experience. Get information about local attractions, weather, transportation options, and more.

  • How long is the flight from Chicago to Missouri?

    Airlines like Contour, Southwest, and United Airlines fly from Chicago to Missouri in about 1h 20m. The time it takes to get you to your destination is usually consistent. The distance between Chicago and Missouri is about 251 mi. Most flights are nonstop.

  • What are the cheapest airlines to fly from Chicago to Missouri one-way?

    The cheapest airline one-way is American Airlines, with whom users have recently found tickets for as low as $48. However, be on the lookout for offers from Contour and Frontier, as they are both options that can get you from Chicago to Missouri for a low price.

  • What are the most popular routes from Chicago to Missouri?

    While some choose either Chicago O'Hare Intl - Lambert-St Louis or Chicago Midway - Kansas City, Chicago O'Hare Intl - Kansas City is the most popular route from Chicago to Missouri.

  • What are the most reliable airlines from Chicago to Missouri?

    The top 3 most reliable airlines when flying from Chicago to Missouri are Turkish Airlines (73%), American Airlines (71%) and Qatar Airways (70%).

  • What are the cheapest flights from Chicago to Missouri?

    The cheapest flight price from Chicago to Missouri is $152. On average you can expect to pay $421. The most popular route, (Chicago O'Hare Intl - Kansas City), can usually be booked for $189.

  • Can I find deals for flights from Chicago to Missouri that include hotel bookings?

    Yes. In addition to deals on Chicago to Missouri flights, Cheapflights offers vacation packages that include both flights and hotel.

  • How can I find direct flights from Chicago to Missouri?

    After entering your origin and destination, apply the non-stop filter on the search result page to find direct flights from Chicago to Missouri.

  • Can I find deals for business class flights from Chicago to Missouri?

    Yes. Cheapflights offers flight deals from Chicago to Missouri by cabin class. In addition to browsing deals, you can also filter by cabin class on the search results page after making a search.

  • What is the cheapest month to book a flight from Chicago to Missouri?

    Currently, August is the cheapest month in which you can book a flight from Chicago to Missouri (average of $77). Flying from Chicago to Missouri in February is currently the most expensive (average of $169). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.

See more FAQs

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Alternative routes for Chicago to Missouri

See prices for flight routes from nearby airports that may be better suited for you.
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Top 5 airlines flying from Chicago to Missouri

Discover the top 5 airlines that operate flights from Chicago to Missouri. Compare their services, reliability, and customer satisfaction ratings to choose the airline that best suits your travel preferences and needs. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated January 24, 2026.
AirlineCheapestAverageFlexibilityOn-time
SouthwestCheapest$77Average$346FlexibilityNo cancel feeOn-time63%
ContourCheapest$108Average$173FlexibilityNo cancel feeOn-timeN/A
American AirlinesCheapest$121Average$318FlexibilityNo cancel feeOn-time71%
United AirlinesCheapest$144Average$328FlexibilityNo cancel feeOn-time69%
Southern / MokuleleCheapest$156Average$215FlexibilityNo cancel feeOn-timeN/A

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