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$49+ Cheap flights from Chicago (CHI) to Missouri

This is the cheapest one-way flight price found by a Cheapflights user in the last 72 hours by searching for a flight departing on 1/17. Fares are subject to change and may not be available on all flights or dates of travel.
CHI — STL
Dec 5 — Dec 121
Fri 12/5
Fri 12/12
1 adult, Economy
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Cheap flight deals from Chicago to Missouri

Keep the following information in mind while searching for Chicago to Missouri flight deals. Data was last updated November 5, 2025.

Most accurate provider

eDreams
3 stars

Most trusted provider

eDreams
3 stars

Round-trip from

$121
(Southwest)

One-way from

$49
(Southwest)

Popular in

October

Cheapest in

August

Average price

$300

Good round-trip deal

$129 or less

Good one-way deal

$64 or less
Provider with most accurate pricing for Chicago (CHI)-Lambert-St Louis flight deals.
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Provider most trusted by Cheapflights users for Chicago (CHI)-Lambert-St Louis flights.
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From Chicago (CHI) to Missouri
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One-way flight from Chicago (CHI) to Missouri
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Highest demand for flights based on searches. 9% potential increase in price ($34 potential increase over avg. RT price).
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Cheapest flight prices on average. 3% potential price decrease ($12 potential savings vs. average RT price).
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Average for round-trip flights in November 2025
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Price to beat on a round-trip flight from Chicago (CHI) to Missouri.
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Price to beat on a one-way flight from Chicago (CHI) to Missouri.
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Find flight deals from Chicago to Missouri

Cheapest flights from Chicago to Missouri
Explore the most affordable flight options available from Chicago to Missouri. Find the lowest fares from popular airlines and budget airlines, with prices last updated on November 5, 2025.

This Southwest deal was found by Cheapflights users on 11/4. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 12/912:25 pmMDW - STL
1 stop3h 55mSouthwest
Wed 12/103:20 pmSTL - MDW
1 stop4h 40mSouthwest
Deal found 11/4$121
This Southwest deal was found by Cheapflights users on 11/4. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 12/92:15 pmORD - STL
1 stop5h 45mSouthwest
Wed 12/108:25 amSTL - ORD
1 stop3h 50mSouthwest
Deal found 11/4$121
This Mytrip deal was found by Cheapflights users on 11/5. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Mytrip is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 12/311:50 amORD - CGI
Nonstop1h 35mContour
Wed 12/109:30 amCGI - ORD
Nonstop1h 40mContour
Deal found 11/5$125
This Mytrip deal was found by Cheapflights users on 11/3. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Mytrip is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 11/1811:50 amORD - CGI
Nonstop1h 35mContour
Sat 11/229:30 amCGI - ORD
Nonstop1h 40mContour
Deal found 11/3$126
This Booking.com deal was found by Cheapflights users on 11/2. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Booking.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 12/1111:50 amORD - CGI
Nonstop1h 35mContour
Mon 12/159:30 amCGI - ORD
Nonstop1h 40mContour
Deal found 11/2$129
This Trip.com deal was found by Cheapflights users on 11/3. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Trip.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 11/176:00 amORD - STL
1 stop27h 07mFrontier
Thu 11/203:14 pmSTL - ORD
1 stop8h 54mFrontier
Deal found 11/3$129
This Frontier deal was found by Cheapflights users on 11/4. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Frontier is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 12/62:26 pmORD - STL
1 stop8h 07mFrontier
Mon 12/812:07 pmSTL - ORD
1 stop8h 10mFrontier
Deal found 11/4$130
This Frontier deal was found by Cheapflights users on 11/4. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Frontier is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 12/45:05 amORD - STL
1 stop6h 02mFrontier
Mon 12/810:47 amSTL - ORD
1 stop11h 37mFrontier
Deal found 11/4$131
This Kiwi.com deal was found by Cheapflights users on 11/5. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 12/102:49 pmMDW - STL
1 stop20h 18mFrontier
Fri 12/1210:42 amSTL - MDW
1 stop9h 00mFrontier
Deal found 11/5$135
This Contour deal was found by Cheapflights users on 11/3. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Contour is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 12/411:50 amORD - CGI
Nonstop1h 35mContour
Fri 12/59:30 amCGI - ORD
Nonstop1h 40mContour
Deal found 11/3$139
This Mytrip deal was found by Cheapflights users on 11/4. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Mytrip is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 11/186:05 pmORD - STL
1 stop15h 02mFrontier
Wed 11/197:24 pmSTL - ORD
1 stop21h 49mFrontier
Deal found 11/4$140
This Southwest deal was found by Cheapflights users on 11/4. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 12/49:50 amMDW - STL
1 stop3h 10mSouthwest
Sun 12/75:45 pmSTL - MDW
Nonstop1h 10mSouthwest
Deal found 11/4$146

Cheapflights Fare Finder

 
Customize your flight search to find flights from Chicago to Missouri that fit within your specific budget. Explore options based on user searches and filter the results based on your desired price range. Find flights that match your budget for a cost-effective journey. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated November 5, 2025.
Use the filters below to find and compare flights from Chicago to Missouri that are best for you.

Fly from

Chicago

Fly to

Missouri

Route

Depart

Return

Price

ChicagoCape Girardeau

ORD - CGI

ORDCGI

Chicago O'Hare Intl

Wed 12/3

11:50 am-1:25 pm

Nonstop1h 35m

Cape Girardeau

Wed 12/10

9:30 am-11:10 am

Nonstop1h 40m

$125

ChicagoCape Girardeau

ORD - CGI

ORDCGI

Chicago O'Hare Intl

Wed 1/14

11:50 am-1:25 pm

Nonstop1h 35m

Cape Girardeau

Sat 1/17

9:30 am-11:10 am

Nonstop1h 40m

$126

ChicagoCape Girardeau

ORD - CGI

ORDCGI

Chicago O'Hare Intl

Tue 11/18

11:50 am-1:25 pm

Nonstop1h 35m

Cape Girardeau

Sat 11/22

9:30 am-11:10 am

Nonstop1h 40m

$126

ChicagoCape Girardeau

ORD - CGI

ORDCGI

Chicago O'Hare Intl

Thu 12/11

11:50 am-1:25 pm

Nonstop1h 35m

Cape Girardeau

Mon 12/15

9:30 am-11:10 am

Nonstop1h 40m

$129

ChicagoSt. Louis

MDW - STL

MDWSTL

Chicago Midway

Tue 12/9

1:55 pm-7:25 pm

1 stop5h 30m

Lambert-St Louis

Wed 12/10

8:25 am-1:35 pm

1 stop5h 10m

$137

ChicagoCape Girardeau

ORD - CGI

ORDCGI

Chicago O'Hare Intl

Thu 12/4

11:50 am-1:25 pm

Nonstop1h 35m

Cape Girardeau

Fri 12/5

9:30 am-11:10 am

Nonstop1h 40m

$139

ChicagoCape Girardeau

ORD - CGI

ORDCGI

Chicago O'Hare Intl

Thu 11/20

4:30 pm-6:05 pm

Nonstop1h 35m

Cape Girardeau

Mon 11/24

4:05 pm-5:45 pm

Nonstop1h 40m

$139

ChicagoCape Girardeau

ORD - CGI

ORDCGI

Chicago O'Hare Intl

Wed 11/19

11:50 am-1:25 pm

Nonstop1h 35m

Cape Girardeau

Sun 11/23

9:30 am-11:10 am

Nonstop1h 40m

$139

ChicagoSt. Louis

MDW - STL

MDWSTL

Chicago Midway

Thu 12/11

7:23 pm-9:47 am

1 stop14h 24m

Lambert-St Louis

Sun 12/14

10:42 am-6:12 pm

1 stop7h 30m

$156

ChicagoSt. Louis

MDW - STL

MDWSTL

Chicago Midway

Thu 12/4

5:13 pm-11:42 pm

1 stop6h 29m

Lambert-St Louis

Mon 12/8

5:12 pm-11:47 pm

1 stop6h 35m

$157

Flights are sorted by cheapest round-trip flights first.

Deals found on 11/4

Showing 1-10 of 60 results
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Best time to book a flight from Chicago to Missouri

Have a flexible travel schedule? Discover the best time to fly to Missouri from Chicago with our price prediction graph.
Estimated round-trip price
Rates are based on past data. Find the cheapest month and day to book your flight based on your travel requirements, then search for cheap deals.

Cheapflights Insights

Everything you need to know about your flight from Chicago to Missouri

What is the cheapest month to book a flight from Chicago to Missouri?

Currently, August is the cheapest month in which you can book a flight from Chicago to Missouri (average of $77). Flying from Chicago to Missouri in February is currently the most expensive (average of $161). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.

What is the cheapest time of day to fly from CHI to MO?

Find hourly flight availability from Chicago to Missouri. Discover flight options and departure times throughout the day, allowing you to choose a departure time that suits your schedule. Data last updated November 5, 2025.

It’s optimal to fly from Chicago to Missouri in the evening. By choosing this option you can save up to 11% on the cost of your flight, compared to a flight in the afternoon.

What is the cheapest day to fly from Chicago to Missouri?

Use this chart to determine the cheapest time to fly round-trip from Chicago to Missouri. Price data was last updated on December 16, 2024.

Travelers seeking maximum savings on their Chicago to Missouri flight should consider departing on Friday afternoons when fares are most often at their lowest. Saturday afternoons flights should be avoided if possible as fares are typically the most expensive at this time.

Weekly flight availability from Chicago to Missouri

Explore weekly flight availability from Chicago to Missouri. Discover flights operating on different days of the week, giving you the flexibility to choose a travel day that best fits your plans. Compare info to find the most convenient option for your journey. Data last updated November 5, 2025.

The most flights from CHI to USMO are scheduled on a Monday (65 on average). You will have fewer flight options on Saturday, which is when the least amount of flights are scheduled (43 on average).

Reviews of airlines servicing Missouri

Get insights into the airlines that provide service to Missouri. Read reviews, discover amenities, and learn about the overall travel experience offered by airlines. Use this information to make informed decisions when choosing an airline for your flight to Missouri. Reviews last updated November 5, 2025.
Get a feel of what it's like to fly with Southwest, Contour, and United Airlines from Chicago to Missouri by reading reviews from past customers. You can also see how each airline compares in terms of entertainment options, comfort, food, crew/service, and boarding process.
Southwest
8.0
Very good
4,239 reviews

Entertainment

7.5

Crew

8.6

Comfort

8.0

Boarding

8.1

Food

7.0

Overall

8.0

Reviews

1 / 20
2.0
Mediocre

Mike,Aug 2025

OKC - AUS

AC was not adequate, even on a night flight. WiFi subpar even for the airlines
Southwest
8.0
Very good
4,239 reviews
Southwest
8.0
Very good
4,239 reviews

Entertainment

7.5

Crew

8.6

Comfort

8.0

Boarding

8.1

Food

7.0

Overall

8.0

Reviews

1 / 20
2.0
Mediocre

Mike,Aug 2025

OKC - AUS

AC was not adequate, even on a night flight. WiFi subpar even for the airlines
Contour
7.5
Good
40 reviews
Southwest
8.0
Very good
4,239 reviews

Entertainment

7.5

Crew

8.6

Comfort

8.0

Boarding

8.1

Food

7.0

Overall

8.0

Reviews

1 / 20
2.0
Mediocre

Mike,Aug 2025

OKC - AUS

AC was not adequate, even on a night flight. WiFi subpar even for the airlines
United Airlines
7.4
Good
9,000 reviews
Southwest
8.0
Very good
4,239 reviews

Entertainment

7.5

Crew

8.6

Comfort

8.0

Boarding

8.1

Food

7.0

Overall

8.0

Reviews

1 / 20
2.0
Mediocre

Mike,Aug 2025

OKC - AUS

AC was not adequate, even on a night flight. WiFi subpar even for the airlines
American Airlines
7.2
Good
11,041 reviews
Southwest
8.0
Very good
4,239 reviews

Entertainment

7.5

Crew

8.6

Comfort

8.0

Boarding

8.1

Food

7.0

Overall

8.0

Reviews

1 / 20
2.0
Mediocre

Mike,Aug 2025

OKC - AUS

AC was not adequate, even on a night flight. WiFi subpar even for the airlines
Southern / Mokulele
6.1
Okay
25 reviews
Southwest
8.0
Very good
4,239 reviews

Entertainment

7.5

Crew

8.6

Comfort

8.0

Boarding

8.1

Food

7.0

Overall

8.0

Reviews

1 / 20
2.0
Mediocre

Mike,Aug 2025

OKC - AUS

AC was not adequate, even on a night flight. WiFi subpar even for the airlines

Related info for your journey

Find useful and relevant information for your journey from Chicago to Missouri. Access travel guides, tips, and recommendations to enhance your travel experience. Get information about local attractions, weather, transportation options, and more.

  • How long is the flight from Chicago to Missouri?

    Airlines like Contour, Southwest, and Frontier fly from Chicago to Missouri in about 1h 35m. The time it takes to get you to your destination can typically vary by up to 12h 49m. The distance between Chicago and Missouri is about 340 mi. When browsing for deals, the options you’ll see will be for both nonstop flights and flights with stops.

  • What are the cheapest airlines to fly from Chicago to Missouri one-way?

    The cheapest airline one-way is Southwest, with whom users have recently found tickets for as low as $49. However, be on the lookout for offers from United Airlines and Contour, as they are both options that can get you from Chicago to Missouri for a low price.

  • What are the most popular routes from Chicago to Missouri?

    While some choose either Chicago O'Hare Intl - Lambert-St Louis or Chicago Midway - Kansas City, Chicago O'Hare Intl - Kansas City is the most popular route from Chicago to Missouri.

  • What are the most reliable airlines from Chicago to Missouri?

    The top 3 most reliable airlines when flying from Chicago to Missouri are Envoy Air (92%), Turkish Airlines (90%) and United Airlines (89%).

  • What are the cheapest flights from Chicago to Missouri?

    The cheapest flight price from Chicago to Missouri is $63. On average you can expect to pay $283. The most popular route, (Chicago O'Hare Intl - Kansas City), can usually be booked for $191.

  • Can I find deals for flights from Chicago to Missouri that include hotel bookings?

    Yes. In addition to deals on Chicago to Missouri flights, Cheapflights offers vacation packages that include both flights and hotel.

  • How can I find direct flights from Chicago to Missouri?

    After entering your origin and destination, apply the non-stop filter on the search result page to find direct flights from Chicago to Missouri.

  • Can I find deals for business class flights from Chicago to Missouri?

    Yes. Cheapflights offers flight deals from Chicago to Missouri by cabin class. In addition to browsing deals, you can also filter by cabin class on the search results page after making a search.

  • What is the cheapest month to book a flight from Chicago to Missouri?

    Currently, August is the cheapest month in which you can book a flight from Chicago to Missouri (average of $77). Flying from Chicago to Missouri in February is currently the most expensive (average of $161). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.

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Alternative routes for Chicago to Missouri

See prices for flight routes from nearby airports that may be better suited for you.
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Top 5 airlines flying from Chicago to Missouri

Discover the top 5 airlines that operate flights from Chicago to Missouri. Compare their services, reliability, and customer satisfaction ratings to choose the airline that best suits your travel preferences and needs. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated November 5, 2025.
AirlineCheapestAverageFlexibilityOn-time
SouthwestCheapest$77Average$302FlexibilityNo cancel feeOn-time63%
ContourCheapest$114Average$182FlexibilityNo cancel feeOn-timeN/A
American AirlinesCheapest$115Average$329FlexibilityNo cancel feeOn-time71%
Southern / MokuleleCheapest$145Average$214FlexibilityNo cancel feeOn-timeN/A
United AirlinesCheapest$152Average$323FlexibilityNo cancel feeOn-time69%

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