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$49+ Cheap flights from Chicago (CHI) to Missouri

This is the cheapest one-way flight price found by a Cheapflights user in the last 72 hours by searching for a flight departing on 12/31. Fares are subject to change and may not be available on all flights or dates of travel.
CHI — STL
dic. 26 — ene. 21
vie. 12/26
vie. 1/2
1 adult, Economy
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Cheap flight deals from Chicago to Missouri

Keep the following information in mind while searching for Chicago to Missouri flight deals. Data was last updated noviembre 26, 2025.

Most accurate provider

eDreams
3 stars

Most trusted provider

eDreams
3 stars

Round-trip from

$122
(Mytrip)

One-way from

$49
(Southwest)

Popular in

October

Cheapest in

August

Average price

$294

Good round-trip deal

$129 or less

Good one-way deal

$64 or less
Provider with most accurate pricing for Chicago (CHI)-Lambert-St Louis flight deals.
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Provider most trusted by Cheapflights users for Chicago (CHI)-Lambert-St Louis flights.
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From Chicago (CHI) to Missouri
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One-way flight from Chicago (CHI) to Missouri
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Highest demand for flights based on searches. 4% potential increase in price ($14 potential increase over avg. RT price).
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Cheapest flight prices on average. 2% potential price decrease ($7 potential savings vs. average RT price).
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Average for round-trip flights in November 2025
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Price to beat on a round-trip flight from Chicago (CHI) to Missouri.
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Price to beat on a one-way flight from Chicago (CHI) to Missouri.
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Find flight deals from Chicago to Missouri

Cheapest flights from Chicago to Missouri
Explore the most affordable flight options available from Chicago to Missouri. Find the lowest fares from popular airlines and budget airlines, with prices last updated on noviembre 26, 2025.

This Mytrip deal was found by Cheapflights users on 11/25. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Mytrip is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
mié. 12/1011:50 amORD - CGI
Nonstop1h 35mContour
dom. 12/149:30 amCGI - ORD
Nonstop1h 40mContour
Deal found 11/25$122
This Gotogate deal was found by Cheapflights users on 11/25. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Gotogate is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
mié. 12/311:50 amORD - CGI
Nonstop1h 35mContour
mié. 12/109:30 amCGI - ORD
Nonstop1h 40mContour
Deal found 11/25$124
This American Airlines deal was found by Cheapflights users on 11/24. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
mié. 12/3112:10 pmORD - STL
Nonstop1h 26mAmerican Airlines
mar. 1/1311:05 amSTL - ORD
Nonstop1h 29mAmerican Airlines
Deal found 11/24$141
This American Airlines deal was found by Cheapflights users on 11/26. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
mié. 12/176:52 pmORD - STL
Nonstop1h 32mAmerican Airlines
mié. 12/246:00 amSTL - ORD
Nonstop1h 27mAmerican Airlines
Deal found 11/26$147
This United Airlines deal was found by Cheapflights users on 11/25. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
lun. 12/225:50 pmORD - STL
Nonstop1h 28mUnited Airlines
mié. 12/246:30 amSTL - ORD
Nonstop1h 35mUnited Airlines
Deal found 11/25$156
This Delta deal was found by Cheapflights users on 11/24. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
mié. 12/244:01 pmORD - STL
1 stop6h 15mDelta
jue. 12/256:29 amSTL - ORD
1 stop6h 25mDelta
Deal found 11/24$157
This Frontier deal was found by Cheapflights users on 11/26. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Frontier is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
jue. 12/113:10 pmMDW - STL
1 stop7h 23mFrontier
lun. 12/159:54 amSTL - MDW
1 stop12h 04mFrontier
Deal found 11/26$162
This Frontier deal was found by Cheapflights users on 11/25. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Frontier is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
jue. 12/119:53 pmORD - STL
1 stop13h 29mFrontier
lun. 12/1510:47 amSTL - ORD
1 stop6h 40mFrontier
Deal found 11/25$162
This Contour deal was found by Cheapflights users on 11/25. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Contour is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
mié. 12/311:50 amORD - CGI
Nonstop1h 35mContour
sáb. 12/69:30 amCGI - ORD
Nonstop1h 40mContour
Deal found 11/25$163
This Delta deal was found by Cheapflights users on 11/24. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
mié. 12/316:35 amORD - STL
1 stop4h 37mDelta
mar. 1/139:59 amSTL - ORD
1 stop6h 45mDelta
Deal found 11/24$178
This American Airlines deal was found by Cheapflights users on 11/26. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
vie. 12/195:27 pmORD - COU
Nonstop1h 27mAmerican Airlines
dom. 12/217:24 pmCOU - ORD
Nonstop1h 40mAmerican Airlines
Deal found 11/26$179
This Frontier deal was found by Cheapflights users on 11/24. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Frontier is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
vie. 12/123:52 pmMDW - STL
1 stop6h 41mFrontier
lun. 12/153:30 pmSTL - MDW
1 stop6h 28mFrontier
Deal found 11/24$187

Cheapflights Fare Finder

 
Customize your flight search to find flights from Chicago to Missouri that fit within your specific budget. Explore options based on user searches and filter the results based on your desired price range. Find flights that match your budget for a cost-effective journey. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated noviembre 26, 2025.
Use the filters below to find and compare flights from Chicago to Missouri that are best for you.

Fly from

Chicago

Fly to

Missouri

Route

Depart

Return

Price

ChicagoCape Girardeau

ORD - CGI

ORDCGI

Chicago O'Hare Intl

mié. 12/10

11:50 am-1:25 pm

Nonstop1h 35m

Cape Girardeau

dom. 12/14

9:30 am-11:10 am

Nonstop1h 40m

$122

ChicagoCape Girardeau

ORD - CGI

ORDCGI

Chicago O'Hare Intl

mié. 12/3

11:50 am-1:25 pm

Nonstop1h 35m

Cape Girardeau

mié. 12/10

9:30 am-11:10 am

Nonstop1h 40m

$124

ChicagoSt. Louis

MDW - STL

MDWSTL

Chicago Midway

dom. 1/18

9:55 am-11:15 am

Nonstop1h 20m

Lambert-St Louis

mié. 1/21

1:10 pm-2:15 pm

Nonstop1h 05m

$138

ChicagoSt. Louis

ORD - STL

ORDSTL

Chicago O'Hare Intl

lun. 12/22

5:50 pm-7:18 pm

Nonstop1h 28m

Lambert-St Louis

mié. 12/24

6:30 am-8:05 am

Nonstop1h 35m

$156

ChicagoSt. Louis

MDW - STL

MDWSTL

Chicago Midway

jue. 1/15

8:15 am-9:35 am

Nonstop1h 20m

Lambert-St Louis

dom. 1/18

5:55 pm-7:05 pm

Nonstop1h 10m

$156

ChicagoSt. Louis

MDW - STL

MDWSTL

Chicago Midway

sáb. 1/17

1:28 pm-4:53 pm

1 stop3h 25m

Lambert-St Louis

dom. 1/18

6:10 am-1:09 pm

1 stop6h 59m

$157

ChicagoSt. Louis

ORD - STL

ORDSTL

Chicago O'Hare Intl

sáb. 1/17

8:00 am-2:49 pm

1 stop6h 49m

Lambert-St Louis

dom. 1/18

6:10 am-11:47 am

1 stop5h 37m

$157

ChicagoSt. Louis

ORD - STL

ORDSTL

Chicago O'Hare Intl

sáb. 1/17

10:52 am-12:29 pm

Nonstop1h 37m

Lambert-St Louis

dom. 1/18

3:11 pm-4:55 pm

Nonstop1h 44m

$159

ChicagoCape Girardeau

ORD - CGI

ORDCGI

Chicago O'Hare Intl

mié. 12/3

11:50 am-1:25 pm

Nonstop1h 35m

Cape Girardeau

sáb. 12/6

9:30 am-11:10 am

Nonstop1h 40m

$163

ChicagoSt. Louis

MDW - STL

MDWSTL

Chicago Midway

sáb. 1/17

9:50 am-5:00 pm

1 stop7h 10m

Lambert-St Louis

dom. 1/18

5:55 pm-7:05 pm

Nonstop1h 10m

$166

Flights are sorted by cheapest round-trip flights first.

Deals found on 11/23

Showing 1-10 of 60 results
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Best time to book a flight from Chicago to Missouri

Have a flexible travel schedule? Discover the best time to fly to Missouri from Chicago with our price prediction graph.
Estimated round-trip price
Rates are based on past data. Find the cheapest month and day to book your flight based on your travel requirements, then search for cheap deals.

Cheapflights Insights

Everything you need to know about your flight from Chicago to Missouri

What is the cheapest month to book a flight from Chicago to Missouri?

Currently, August is the cheapest month in which you can book a flight from Chicago to Missouri (average of $77). Flying from Chicago to Missouri in February is currently the most expensive (average of $160). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.

What is the cheapest time of day to fly from CHI to MO?

Find hourly flight availability from Chicago to Missouri. Discover flight options and departure times throughout the day, allowing you to choose a departure time that suits your schedule. Data last updated noviembre 26, 2025.

It’s optimal to fly from Chicago to Missouri in the evening. By choosing this option you can save up to 12% on the cost of your flight, compared to a flight in the afternoon.

What is the cheapest day to fly from Chicago to Missouri?

Use this chart to determine the cheapest time to fly round-trip from Chicago to Missouri. Price data was last updated on December 16, 2024.

Travelers seeking maximum savings on their Chicago to Missouri flight should consider departing on Friday afternoons when fares are most often at their lowest. Saturday afternoons flights should be avoided if possible as fares are typically the most expensive at this time.

Weekly flight availability from Chicago to Missouri

Explore weekly flight availability from Chicago to Missouri. Discover flights operating on different days of the week, giving you the flexibility to choose a travel day that best fits your plans. Compare info to find the most convenient option for your journey. Data last updated noviembre 26, 2025.

The most flights from CHI to USMO are scheduled on a Monday (72 on average). You will have fewer flight options on Thursday, which is when the least amount of flights are scheduled (8 on average).

How much does it cost to fly round-trip from Chicago to Missouri?

Reviews of airlines servicing Missouri

Get insights into the airlines that provide service to Missouri. Read reviews, discover amenities, and learn about the overall travel experience offered by airlines. Use this information to make informed decisions when choosing an airline for your flight to Missouri. Reviews last updated noviembre 26, 2025.
Get a feel of what it's like to fly with Southwest, Contour, and United Airlines from Chicago to Missouri by reading reviews from past customers. You can also see how each airline compares in terms of entertainment options, comfort, food, crew/service, and boarding process.
Southwest
8.0
Very good
4,254 reviews

Comfort

8.0

Crew

8.6

Overall

8.0

Food

7.0

Entertainment

7.5

Boarding

8.1

Reviews

1 / 20
2.0
Mediocre

Mike,Aug 2025

OKC - AUS

AC was not adequate, even on a night flight. WiFi subpar even for the airlines
Southwest
8.0
Very good
4,254 reviews
Southwest
8.0
Very good
4,254 reviews

Comfort

8.0

Crew

8.6

Overall

8.0

Food

7.0

Entertainment

7.5

Boarding

8.1

Reviews

1 / 20
2.0
Mediocre

Mike,Aug 2025

OKC - AUS

AC was not adequate, even on a night flight. WiFi subpar even for the airlines
Contour
7.6
Good
42 reviews
Southwest
8.0
Very good
4,254 reviews

Comfort

8.0

Crew

8.6

Overall

8.0

Food

7.0

Entertainment

7.5

Boarding

8.1

Reviews

1 / 20
2.0
Mediocre

Mike,Aug 2025

OKC - AUS

AC was not adequate, even on a night flight. WiFi subpar even for the airlines
United Airlines
7.4
Good
9,046 reviews
Southwest
8.0
Very good
4,254 reviews

Comfort

8.0

Crew

8.6

Overall

8.0

Food

7.0

Entertainment

7.5

Boarding

8.1

Reviews

1 / 20
2.0
Mediocre

Mike,Aug 2025

OKC - AUS

AC was not adequate, even on a night flight. WiFi subpar even for the airlines
American Airlines
7.2
Good
11,038 reviews
Southwest
8.0
Very good
4,254 reviews

Comfort

8.0

Crew

8.6

Overall

8.0

Food

7.0

Entertainment

7.5

Boarding

8.1

Reviews

1 / 20
2.0
Mediocre

Mike,Aug 2025

OKC - AUS

AC was not adequate, even on a night flight. WiFi subpar even for the airlines
Southern / Mokulele
6.4
Okay
27 reviews
Southwest
8.0
Very good
4,254 reviews

Comfort

8.0

Crew

8.6

Overall

8.0

Food

7.0

Entertainment

7.5

Boarding

8.1

Reviews

1 / 20
2.0
Mediocre

Mike,Aug 2025

OKC - AUS

AC was not adequate, even on a night flight. WiFi subpar even for the airlines

Related info for your journey

Find useful and relevant information for your journey from Chicago to Missouri. Access travel guides, tips, and recommendations to enhance your travel experience. Get information about local attractions, weather, transportation options, and more.

  • How long is the flight from Chicago to Missouri?

    Airlines like Contour, Southwest, and United Airlines fly from Chicago to Missouri in about 1h 20m. The time it takes to get you to your destination is usually consistent. The distance between Chicago and Missouri is about 251 mi. Most flights are nonstop.

  • What are the cheapest airlines to fly from Chicago to Missouri one-way?

    The cheapest airline one-way is Southwest, with whom users have recently found tickets for as low as $49. However, be on the lookout for offers from United Airlines and Contour, as they are both options that can get you from Chicago to Missouri for a low price.

  • What are the most popular routes from Chicago to Missouri?

    While some choose either Chicago O'Hare Intl - Lambert-St Louis or Chicago Midway - Lambert-St Louis, Chicago O'Hare Intl - Kansas City is the most popular route from Chicago to Missouri.

  • What are the most reliable airlines from Chicago to Missouri?

    The top 3 most reliable airlines when flying from Chicago to Missouri are Turkish Airlines (90%), United Airlines (84%) and Envoy Air (84%).

  • What are the cheapest flights from Chicago to Missouri?

    The cheapest flight price from Chicago to Missouri is $58. On average you can expect to pay $369. The most popular route, (Chicago O'Hare Intl - Kansas City), can usually be booked for $172.

  • Can I find deals for flights from Chicago to Missouri that include hotel bookings?

    Yes. In addition to deals on Chicago to Missouri flights, Cheapflights offers vacation packages that include both flights and hotel.

  • How can I find direct flights from Chicago to Missouri?

    After entering your origin and destination, apply the non-stop filter on the search result page to find direct flights from Chicago to Missouri.

  • Can I find deals for business class flights from Chicago to Missouri?

    Yes. Cheapflights offers flight deals from Chicago to Missouri by cabin class. In addition to browsing deals, you can also filter by cabin class on the search results page after making a search.

  • What is the cheapest month to book a flight from Chicago to Missouri?

    Currently, August is the cheapest month in which you can book a flight from Chicago to Missouri (average of $77). Flying from Chicago to Missouri in February is currently the most expensive (average of $160). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.

See more FAQs

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Alternative routes for Chicago to Missouri

See prices for flight routes from nearby airports that may be better suited for you.
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Top 5 airlines flying from Chicago to Missouri

Discover the top 5 airlines that operate flights from Chicago to Missouri. Compare their services, reliability, and customer satisfaction ratings to choose the airline that best suits your travel preferences and needs. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated noviembre 26, 2025.
AirlineCheapestAverageFlexibilityOn-time
SouthwestCheapest$77Average$334FlexibilityNo cancel feeOn-time63%
ContourCheapest$114Average$183FlexibilityNo cancel feeOn-timeN/A
American AirlinesCheapest$121Average$327FlexibilityNo cancel feeOn-time71%
Southern / MokuleleCheapest$145Average$214FlexibilityNo cancel feeOn-timeN/A
United AirlinesCheapest$152Average$328FlexibilityNo cancel feeOn-time69%

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