$80+ Cheap flights from Chicago (CHI) to Missouri
This is the cheapest one-way flight price found by a Cheapflights user in the last 72 hours by searching for a flight departing on 9/21. Fares are subject to change and may not be available on all flights or dates of travel.
CHI — MCI
Aug 7 — Aug 141
Round-trip
1 adult, Economy
We work with more than 300 partners to bring you better travel deals
Find cheap flights from Chicago to Missouri with Cheapflights
1. Tell us where you want to go
Enter your travel information like dates, passengers, trip type (one-way or round trip), and preferred cabin class then click “Find deals”2. Select your favorite providers
We find the providers serving your travel needs. Choose up to four travel providers to compare side-by-side for flights, hotels, or car rentals.3. Compare prices and book
Review each provider’s pricing and select the best option for you! Book through your favorite provider’s website for a seamless experience.Cheap flight deals from Chicago to Missouri
Cheapest
Best
Last-minute
One-way
Cheapest flights from Chicago to MissouriExplore the most affordable flight options available from Chicago to Missouri. Find the lowest fares from popular airlines and budget airlines, with prices last updated on July 8, 2026.
Explore the most affordable flight options available from Chicago to Missouri. Find the lowest fares from popular airlines and budget airlines, with prices last updated on July 8, 2026.
This Mytrip deal was found by Cheapflights users on 7/7. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Mytrip is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 10/2111:15 am
ORD
- CGI
Nonstop1h 35m
Contour
Sun 10/259:40 am
CGI
- ORD
Nonstop1h 55m
Contour
Deal found 7/7![Contour logo]()
$158
This Mytrip deal was found by Cheapflights users on 7/7. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Mytrip is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 10/2211:15 am
ORD
- CGI
Nonstop1h 35m
Contour
Sun 10/259:40 am
CGI
- ORD
Nonstop1h 55m
Contour
Deal found 7/7![Contour logo]()
$160
This Mytrip deal was found by Cheapflights users on 7/6. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Mytrip is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 8/611:15 am
ORD
- CGI
Nonstop1h 35m
Contour
Sun 8/99:50 am
CGI
- ORD
Nonstop1h 55m
Contour
Deal found 7/6![Contour logo]()
$162
This Mytrip deal was found by Cheapflights users on 7/3. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Mytrip is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 7/3112:10 pm
ORD
- CGI
Nonstop1h 40m
Contour
Fri 8/79:50 am
CGI
- ORD
Nonstop1h 55m
Contour
Deal found 7/3![Contour logo]()
$163
This Trip.com deal was found by Cheapflights users on 7/5. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Trip.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 8/2411:15 am
ORD
- CGI
Nonstop1h 35m
Contour
Tue 9/19:50 am
CGI
- ORD
Nonstop1h 55m
Contour
Deal found 7/5![Contour logo]()
$173
This Kiwi.com deal was found by Cheapflights users on 7/5. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 8/2311:15 am
ORD
- CGI
Nonstop1h 35m
Contour
Wed 9/21:30 pm
CGI
- ORD
Nonstop1h 50m
Contour
Deal found 7/5![Contour logo]()
$178
This Mytrip deal was found by Cheapflights users on 7/7. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Mytrip is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 7/2112:10 pm
ORD
- CGI
Nonstop1h 40m
Contour
Tue 7/289:50 am
CGI
- ORD
Nonstop1h 45m
Contour
Deal found 7/7![Contour logo]()
$192
This Mytrip deal was found by Cheapflights users on 7/6. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Mytrip is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 11/2712:15 pm
ORD
- CGI
Nonstop1h 35m
Contour
Mon 11/309:40 am
CGI
- ORD
Nonstop1h 55m
Contour
Deal found 7/6![Contour logo]()
$213
This Kiwi.com deal was found by Cheapflights users on 7/3. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 8/211:15 am
ORD
- CGI
Nonstop1h 35m
Contour
Sat 8/81:30 pm
CGI
- ORD
Nonstop1h 50m
Contour
Deal found 7/3![Contour logo]()
$233
This American Airlines deal was found by Cheapflights users on 7/3. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 8/177:49 pm
ORD
- COU
Nonstop1h 30m
American Airlines
Mon 8/2412:43 pm
COU
- ORD
Nonstop1h 36m
American Airlines
Deal found 7/3![American Airlines logo]()
$238
This United Airlines deal was found by Cheapflights users on 7/3. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 8/2812:50 pm
ORD
- COU
Nonstop1h 40m
United Airlines
Sun 8/3010:55 am
COU
- ORD
Nonstop1h 43m
United Airlines
Deal found 7/3![United Airlines logo]()
$239
This Mytrip deal was found by Cheapflights users on 7/7. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Mytrip is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 9/411:15 am
ORD
- CGI
Nonstop1h 35m
Contour
Sun 9/69:50 am
CGI
- ORD
Nonstop1h 55m
Contour
Deal found 7/7![Contour logo]()
$247
Best flights from Chicago to MissouriDiscover carefully curated flight deals from Chicago to Missouri that have cost, travel time, and layovers in mind to ensure you get the best travel experience. Data last updated July 8, 2026.
Discover carefully curated flight deals from Chicago to Missouri that have cost, travel time, and layovers in mind to ensure you get the best travel experience. Data last updated July 8, 2026.
This Mytrip deal was found by Cheapflights users on 7/7. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Mytrip is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 10/2211:15 am
ORD
- CGI
Nonstop1h 35m
Contour
Sun 10/259:40 am
CGI
- ORD
Nonstop1h 55m
Contour
Deal found 7/7![Contour logo]()
$160
This United Airlines deal was found by Cheapflights users on 7/7. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 9/179:20 pm
ORD
- COU
Nonstop1h 35m
United Airlines
Mon 9/2111:17 am
COU
- ORD
Nonstop1h 43m
United Airlines
Deal found 7/7![United Airlines logo]()
$239
This Delta deal was found by Cheapflights users on 7/7. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 8/218:05 am
ORD
- SGF
1 stop6h 33m
Delta
Fri 8/2811:38 am
SGF
- ORD
1 stop7h 11m
Delta
Deal found 7/7![Delta logo]()
$269
This Southwest deal was found by Cheapflights users on 7/7. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 8/89:55 am
MDW
- STL
2 stops6h 45m
Southwest
Mon 8/105:40 pm
STL
- MDW
1 stop4h 40m
Southwest
Deal found 7/7![Southwest logo]()
$301
This Kiwi.com deal was found by Cheapflights users on 7/3. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 9/411:15 am
ORD
- CGI
Nonstop1h 35m
Multiple Airlines
Mon 9/73:25 pm
CGI
- ORD
1 stop24h 35m
Multiple Airlines
Deal found 7/3![Multiple Airlines logo]()
$314
This Mytrip deal was found by Cheapflights users on 7/6. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Mytrip is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 8/611:15 am
ORD
- CGI
Nonstop1h 35m
Contour
Sun 8/99:50 am
CGI
- ORD
Nonstop1h 55m
Contour
Deal found 7/6![Contour logo]()
$162
This American Airlines deal was found by Cheapflights users on 7/7. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 8/2011:00 pm
ORD
- MCI
Nonstop1h 35m
American Airlines
Sun 8/236:20 am
MCI
- ORD
1 stop5h 55m
American Airlines
Deal found 7/7![American Airlines logo]()
$354
This Mytrip deal was found by Cheapflights users on 7/3. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Mytrip is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 7/3112:10 pm
ORD
- CGI
Nonstop1h 40m
Contour
Fri 8/79:50 am
CGI
- ORD
Nonstop1h 55m
Contour
Deal found 7/3![Contour logo]()
$163
This Kiwi.com deal was found by Cheapflights users on 7/7. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 7/317:05 am
ORD
- MCI
1 stop10h 05m
Frontier
Sun 8/21:45 pm
MCI
- ORD
2 stops18h 08m
Frontier
Deal found 7/7![Frontier logo]()
$400
This Contour deal was found by Cheapflights users on 7/4. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Contour is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 10/1711:15 am
ORD
- CGI
Nonstop1h 35m
Contour
Tue 10/209:40 am
CGI
- ORD
Nonstop1h 55m
Contour
Deal found 7/4![Contour logo]()
$178
This Contour deal was found by Cheapflights users on 7/4. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Contour is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 8/194:00 pm
ORD
- CGI
Nonstop1h 35m
Contour
Sun 8/239:50 am
CGI
- ORD
Nonstop1h 55m
Contour
Deal found 7/4![Contour logo]()
$178
This United Airlines deal was found by Cheapflights users on 7/3. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 8/2812:50 pm
ORD
- COU
Nonstop1h 40m
United Airlines
Sun 8/3010:55 am
COU
- ORD
Nonstop1h 43m
United Airlines
Deal found 7/3![United Airlines logo]()
$239
This Delta deal was found by Cheapflights users on 7/5. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 8/219:54 am
ORD
- SGF
1 stop4h 44m
Delta
Sat 8/2211:38 am
SGF
- ORD
1 stop5h 13m
Delta
Deal found 7/5![Delta logo]()
$269
This United Airlines deal was found by Cheapflights users on 7/3. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 8/58:40 am
ORD
- COU
Nonstop1h 33m
United Airlines
Sun 5/28:00 am
COU
- ORD
Nonstop1h 33m
United Airlines
Deal found 7/3![United Airlines logo]()
$247
This Delta deal was found by Cheapflights users on 7/3. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 8/193:25 pm
ORD
- SGF
1 stop6h 56m
Delta
Sat 8/2211:38 am
SGF
- ORD
1 stop7h 21m
Delta
Deal found 7/3![Delta logo]()
$269
This Southwest deal was found by Cheapflights users on 7/7. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 8/2112:00 pm
MDW
- MCI
Nonstop1h 25m
Southwest
Sun 8/237:45 pm
MCI
- MDW
Nonstop1h 25m
Southwest
Deal found 7/7![Southwest logo]()
$317
This United Airlines deal was found by Cheapflights users on 7/6. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 7/2310:00 pm
ORD
- COU
Nonstop1h 33m
United Airlines
Sun 7/268:00 am
COU
- ORD
Nonstop1h 40m
United Airlines
Deal found 7/6![United Airlines logo]()
$269
This Delta deal was found by Cheapflights users on 7/3. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 8/181:25 pm
MDW
- SGF
2 stops8h 56m
Delta
Tue 8/256:06 am
SGF
- MDW
1 stop5h 45m
Delta
Deal found 7/3![Delta logo]()
$274
This Kiwi.com deal was found by Cheapflights users on 7/3. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 8/211:15 am
ORD
- CGI
Nonstop1h 35m
Contour
Sat 8/81:30 pm
CGI
- ORD
Nonstop1h 50m
Contour
Deal found 7/3![Contour logo]()
$233
This Southwest deal was found by Cheapflights users on 7/6. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 8/209:20 am
MDW
- STL
Nonstop1h 10m
Southwest
Thu 8/2711:05 am
STL
- MDW
Nonstop1h 10m
Southwest
Deal found 7/6![Southwest logo]()
$337
This Southwest deal was found by Cheapflights users on 7/5. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 8/1910:10 am
MDW
- STL
Nonstop1h 10m
Southwest
Wed 8/266:30 am
STL
- MDW
Nonstop1h 05m
Southwest
Deal found 7/5![Southwest logo]()
$337
This United Airlines deal was found by Cheapflights users on 7/7. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 8/81:15 pm
ORD
- COU
Nonstop1h 35m
United Airlines
Tue 8/1110:49 am
COU
- ORD
Nonstop1h 40m
United Airlines
Deal found 7/7![United Airlines logo]()
$309
This Delta deal was found by Cheapflights users on 7/7. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 8/77:25 pm
MDW
- MCI
1 stop4h 02m
Delta
Sun 8/96:28 am
MCI
- MDW
1 stop6h 42m
Delta
Deal found 7/7![Delta logo]()
$321
This Southwest deal was found by Cheapflights users on 7/5. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 8/118:15 am
MDW
- STL
Nonstop1h 20m
Southwest
Tue 8/118:45 pm
STL
- MDW
Nonstop1h 05m
Southwest
Deal found 7/5![Southwest logo]()
$337
This United Airlines deal was found by Cheapflights users on 7/5. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 10/99:00 am
ORD
- COU
Nonstop1h 37m
United Airlines
Sun 10/116:15 am
COU
- ORD
Nonstop1h 38m
United Airlines
Deal found 7/5![United Airlines logo]()
$309
This Contour deal was found by Cheapflights users on 7/7. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Contour is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 9/2011:15 am
ORD
- CGI
Nonstop1h 35m
Contour
Thu 9/249:50 am
CGI
- ORD
Nonstop1h 55m
Contour
Deal found 7/7![Contour logo]()
$283
This American Airlines deal was found by Cheapflights users on 7/7. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 7/314:45 pm
ORD
- MCI
1 stop6h 13m
American Airlines
Sun 8/26:28 am
MCI
- ORD
Nonstop2h 01m
American Airlines
Deal found 7/7![American Airlines logo]()
$459
This Contour deal was found by Cheapflights users on 7/7. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Contour is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 9/1211:15 am
ORD
- CGI
Nonstop1h 35m
Contour
Sun 9/139:50 am
CGI
- ORD
Nonstop1h 55m
Contour
Deal found 7/7![Contour logo]()
$283
This Southwest deal was found by Cheapflights users on 7/4. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 8/39:35 pm
MDW
- STL
Nonstop1h 20m
Southwest
Mon 8/106:05 pm
STL
- MDW
1 stop5h 40m
Southwest
Deal found 7/4![Southwest logo]()
$347
This United Airlines deal was found by Cheapflights users on 7/7. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 8/69:30 pm
ORD
- SGF
Nonstop1h 57m
United Airlines
Thu 8/136:37 pm
SGF
- ORD
Nonstop2h 00m
United Airlines
Deal found 7/7![United Airlines logo]()
$320
Last-minute flights from Chicago to MissouriDiscover last-minute flight deals from Chicago to Missouri. Data last updated July 8, 2026 and is based on user searches.
Discover last-minute flight deals from Chicago to Missouri. Data last updated July 8, 2026 and is based on user searches.
This Mytrip deal was found by Cheapflights users on 7/7. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Mytrip is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 7/2112:10 pm
ORD
- CGI
Nonstop1h 40m
Contour
Tue 7/289:50 am
CGI
- ORD
Nonstop1h 45m
Contour
Deal found 7/7![Contour logo]()
$192
This Mytrip deal was found by Cheapflights users on 7/3. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Mytrip is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 7/3112:10 pm
ORD
- CGI
Nonstop1h 40m
Contour
Fri 8/79:50 am
CGI
- ORD
Nonstop1h 55m
Contour
Deal found 7/3![Contour logo]()
$163
This American Airlines deal was found by Cheapflights users on 7/7. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 8/111:56 am
ORD
- SGF
Nonstop1h 44m
American Airlines
Sun 8/27:53 pm
SGF
- ORD
Nonstop1h 52m
American Airlines
Deal found 7/7![American Airlines logo]()
$250
This Kiwi.com deal was found by Cheapflights users on 7/3. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 8/211:15 am
ORD
- CGI
Nonstop1h 35m
Contour
Sat 8/81:30 pm
CGI
- ORD
Nonstop1h 50m
Contour
Deal found 7/3![Contour logo]()
$233
This United Airlines deal was found by Cheapflights users on 7/3. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 8/58:40 am
ORD
- COU
Nonstop1h 33m
United Airlines
Sun 5/28:00 am
COU
- ORD
Nonstop1h 33m
United Airlines
Deal found 7/3![United Airlines logo]()
$247
This Mytrip deal was found by Cheapflights users on 7/6. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Mytrip is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 8/611:15 am
ORD
- CGI
Nonstop1h 35m
Contour
Sun 8/99:50 am
CGI
- ORD
Nonstop1h 55m
Contour
Deal found 7/6![Contour logo]()
$162
This American Airlines deal was found by Cheapflights users on 7/7. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 8/78:57 pm
ORD
- SGF
Nonstop1h 46m
American Airlines
Sat 8/85:06 pm
SGF
- ORD
Nonstop1h 54m
American Airlines
Deal found 7/7![American Airlines logo]()
$249
This American Airlines deal was found by Cheapflights users on 7/3. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 8/177:49 pm
ORD
- COU
Nonstop1h 30m
American Airlines
Mon 8/2412:43 pm
COU
- ORD
Nonstop1h 36m
American Airlines
Deal found 7/3![American Airlines logo]()
$238
This American Airlines deal was found by Cheapflights users on 7/4. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 8/188:20 am
ORD
- SGF
Nonstop1h 44m
American Airlines
Tue 8/257:15 am
SGF
- ORD
Nonstop1h 55m
American Airlines
Deal found 7/4![American Airlines logo]()
$248
This Kiwi.com deal was found by Cheapflights users on 7/5. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 8/2311:15 am
ORD
- CGI
Nonstop1h 35m
Contour
Wed 9/21:30 pm
CGI
- ORD
Nonstop1h 50m
Contour
Deal found 7/5![Contour logo]()
$178
This Trip.com deal was found by Cheapflights users on 7/5. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Trip.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 8/2411:15 am
ORD
- CGI
Nonstop1h 35m
Contour
Tue 9/19:50 am
CGI
- ORD
Nonstop1h 55m
Contour
Deal found 7/5![Contour logo]()
$173
This United Airlines deal was found by Cheapflights users on 7/3. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 8/2812:50 pm
ORD
- COU
Nonstop1h 40m
United Airlines
Sun 8/3010:55 am
COU
- ORD
Nonstop1h 43m
United Airlines
Deal found 7/3![United Airlines logo]()
$239
One-way flights from Chicago to MissouriSearch for one-way flight options from Chicago to Missouri. Find affordable one-way fares based on user searches. Data last updated July 8, 2026.
Search for one-way flight options from Chicago to Missouri. Find affordable one-way fares based on user searches. Data last updated July 8, 2026.
This Mytrip deal was found by Cheapflights users on 7/5. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Mytrip is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 9/2111:15 am
ORD
- CGI
Nonstop1h 35m
Contour
Deal found 7/5![Contour logo]()
$80
This Booking.com deal was found by Cheapflights users on 7/5. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Booking.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 7/1912:10 pm
ORD
- CGI
Nonstop1h 40m
Contour
Deal found 7/5![Contour logo]()
$81
This Southwest deal was found by Cheapflights users on 7/3. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 8/178:55 pm
MDW
- STL
Nonstop1h 10m
Southwest
Deal found 7/3![Southwest logo]()
$98
This United Airlines deal was found by Cheapflights users on 7/3. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 8/83:59 pm
ORD
- STL
Nonstop1h 28m
United Airlines
Deal found 7/3![United Airlines logo]()
$98
This Super.com deal was found by Cheapflights users on 7/6. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Super.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 8/412:11 pm
MDW
- STL
1 stop5h 26m
Frontier
Deal found 7/6![Frontier logo]()
$104
This Super.com deal was found by Cheapflights users on 7/3. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Super.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 9/19:20 am
ORD
- STL
1 stop7h 11m
Frontier
Deal found 7/3![Frontier logo]()
$104
This Priceline deal was found by Cheapflights users on 7/6. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Priceline is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 8/49:28 am
ORD
- STL
1 stop5h 28m
Frontier
Deal found 7/6![Frontier logo]()
$105
This American Airlines deal was found by Cheapflights users on 7/7. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 9/308:57 am
ORD
- STL
Nonstop1h 23m
American Airlines
Deal found 7/7![American Airlines logo]()
$107
This Booking.com deal was found by Cheapflights users on 7/7. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Booking.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 7/253:55 pm
ORD
- CGI
Nonstop1h 40m
Contour
Deal found 7/7![Contour logo]()
$108
This Southwest deal was found by Cheapflights users on 7/7. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 9/304:40 pm
MDW
- STL
Nonstop1h 15m
Southwest
Deal found 7/7![Southwest logo]()
$108
This Delta deal was found by Cheapflights users on 7/3. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 9/308:55 am
ORD
- STL
1 stop4h 11m
Delta
Deal found 7/3![Delta logo]()
$108
This Super.com deal was found by Cheapflights users on 7/7. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Super.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 7/2812:11 pm
MDW
- STL
1 stop5h 26m
Frontier
Deal found 7/7![Frontier logo]()
$114
Find flight deals from Chicago to Missouri
Keep the following information in mind while searching for Chicago to Missouri flight deals. Data was last updated July 8, 2026.
Most accurate provider | FlightHub 3 stars |
|---|---|
Most trusted provider | FlightHub 3 stars |
Round-trip from | $158 (Mytrip) |
One-way from | $80 (Mytrip) |
Popular in | April |
Cheapest in | December |
Average price | $442 |
Good round-trip deal | $223 or less |
Good one-way deal | $62 or less |
Cheapflights Fare Finder
Customize your flight search to find flights from Chicago to Missouri that fit within your specific budget. Explore options based on user searches and filter the results based on your desired price range. Find flights that match your budget for a cost-effective journey. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated July 8, 2026.
Use the filters below to find and compare flights from Chicago to Missouri that are best for you.
Fly from
Fly to
Route
Depart
Return
Cheapest round-trip
ChicagoCape Girardeau
ORD - CGI
ORDCGI
Chicago O'Hare Intl
Thu 10/22
11:15 am-12:50 pm
Nonstop1h 35m
Cape Girardeau
Sun 10/25
9:40 am-11:35 am
Nonstop1h 55m
$160
ChicagoCape Girardeau
ORD - CGI
ORDCGI
Chicago O'Hare Intl
Thu 8/6
11:15 am-12:50 pm
Nonstop1h 35m
Cape Girardeau
Sun 8/9
9:50 am-11:45 am
Nonstop1h 55m
$162
ChicagoCape Girardeau
ORD - CGI
ORDCGI
Chicago O'Hare Intl
Fri 7/31
12:10 pm-1:50 pm
Nonstop1h 40m
Cape Girardeau
Fri 8/7
9:50 am-11:45 am
Nonstop1h 55m
$163
ChicagoCape Girardeau
ORD - CGI
ORDCGI
Chicago O'Hare Intl
Sat 10/17
11:15 am-12:50 pm
Nonstop1h 35m
Cape Girardeau
Tue 10/20
9:40 am-11:35 am
Nonstop1h 55m
$178
ChicagoCape Girardeau
ORD - CGI
ORDCGI
Chicago O'Hare Intl
Wed 8/19
4:00 pm-5:35 pm
Nonstop1h 35m
Cape Girardeau
Sun 8/23
9:50 am-11:45 am
Nonstop1h 55m
$178
ChicagoCape Girardeau
ORD - CGI
ORDCGI
Chicago O'Hare Intl
Sun 8/2
11:15 am-12:50 pm
Nonstop1h 35m
Cape Girardeau
Sat 8/8
1:30 pm-3:20 pm
Nonstop1h 50m
$233
ChicagoColumbia
ORD - COU
ORDCOU
Chicago O'Hare Intl
Thu 9/17
9:20 pm-10:55 pm
Nonstop1h 35m
Columbia Regional
Mon 9/21
11:17 am-1:00 pm
Nonstop1h 43m
$239
ChicagoColumbia
ORD - COU
ORDCOU
Chicago O'Hare Intl
Fri 8/28
12:50 pm-2:30 pm
Nonstop1h 40m
Columbia Regional
Sun 8/30
10:55 am-12:38 pm
Nonstop1h 43m
$239
ChicagoColumbia
ORD - COU
ORDCOU
Chicago O'Hare Intl
Wed 8/5
8:40 am-10:13 am
Nonstop1h 33m
Columbia Regional
Sun 5/2
8:00 am-9:33 am
Nonstop1h 33m
$247
ChicagoSpringfield
ORD - SGF
ORDSGF
Chicago O'Hare Intl
Fri 8/21
8:05 am-2:38 pm
1 stop6h 33m
Springfield-Branson
Fri 8/28
11:38 am-6:49 pm
1 stop7h 11m
$269
Showing 1-10 of 60 resultsSorted by cheapest first
Best time to book a flight from Chicago to Missouri
Have a flexible travel schedule? Discover the best time to fly to Missouri from Chicago with our price prediction graph.
ORD-CGI
ORD-COU
ORD-SGF
MDW-STL
ORD-STL
Estimated round-trip price
Rates are based on past data. Find the cheapest month and day to book your flight based on your travel requirements, then search for cheap deals.
Cheapflights Insights
Everything you need to know about your flight from Chicago to Missouri
CHI-USMO
ORD-CGI
ORD-COU
ORD-SGF
MDW-STL
What is the cheapest month to book a flight from Chicago to Missouri?
Currently, October is the cheapest month in which you can book a flight from Chicago to Missouri (average of $75). Flying from Chicago to Missouri in June is currently the most expensive (average of $137). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.
What is the cheapest time of day to fly from CHI to MO?
Find hourly flight availability from Chicago to Missouri. Discover flight options and departure times throughout the day, allowing you to choose a departure time that suits your schedule. Data last updated July 8, 2026.
It’s optimal to fly from Chicago to Missouri in the morning. By choosing this option you can save up to 21% on the cost of your flight, compared to a flight in the evening.
Weekly flight availability from Chicago to Missouri
Explore weekly flight availability from Chicago to Missouri. Discover flights operating on different days of the week, giving you the flexibility to choose a travel day that best fits your plans. Compare info to find the most convenient option for your journey. Data last updated July 8, 2026.
The most flights from CHI to USMO are scheduled on a Monday (69 on average). You will have fewer flight options on Saturday, which is when the least amount of flights are scheduled (27 on average).
How much does it cost to fly round-trip from Chicago to Missouri?
How far ahead should I book a flight from Chicago to Missouri?
To ensure you get the cheapest price possible for a flight from Chicago to Missouri, you should look to book at least 79 days in advance of your intended travel date. The price of your flight may increase if you delay and leave booking until a week or so before departure.
What is the cheapest day to fly from Chicago to Missouri?
Use this chart to determine the cheapest time to fly round-trip from Chicago to Missouri. Price data was last updated on July 4, 2026.
Travelers seeking maximum savings on their Chicago to Missouri flight should consider departing on Tuesday afternoons when fares are most often at their lowest. Wednesday at noon flights should be avoided if possible as fares are typically the most expensive at this time.
Reviews of airlines servicing Missouri
Get insights into the airlines that provide service to Missouri. Read reviews, discover amenities, and learn about the overall travel experience offered by airlines. Use this information to make informed decisions when choosing an airline for your flight to Missouri. Reviews last updated July 8, 2026.
Get a feel of what it's like to fly with Southwest,Contour, andUnited Airlines from Chicago to Missouri by reading reviews from past customers. You can also see how each airline compares in terms of entertainment options, comfort, food, crew/service, and boarding process.
Comfort
8.0
Boarding
8.1
Food
7.0
Overall
7.9
Crew
8.6
Entertainment
7.5
Reviews
1 / 20
2.0
MediocreAnonymous,Feb 2025
MCO - STL
Comfort
8.0
Boarding
8.1
Food
7.0
Overall
7.9
Crew
8.6
Entertainment
7.5
Reviews
1 / 20
2.0
MediocreAnonymous,Feb 2025
MCO - STL
Comfort
8.0
Boarding
8.1
Food
7.0
Overall
7.9
Crew
8.6
Entertainment
7.5
Reviews
1 / 20
2.0
MediocreAnonymous,Feb 2025
MCO - STL
Comfort
8.0
Boarding
8.1
Food
7.0
Overall
7.9
Crew
8.6
Entertainment
7.5
Reviews
1 / 20
2.0
MediocreAnonymous,Feb 2025
MCO - STL
Comfort
8.0
Boarding
8.1
Food
7.0
Overall
7.9
Crew
8.6
Entertainment
7.5
Reviews
1 / 20
2.0
MediocreAnonymous,Feb 2025
MCO - STL
Comfort
8.0
Boarding
8.1
Food
7.0
Overall
7.9
Crew
8.6
Entertainment
7.5
Reviews
1 / 20
2.0
MediocreAnonymous,Feb 2025
MCO - STL
Related info for your journey
Find useful and relevant information for your journey from Chicago to Missouri. Access travel guides, tips, and recommendations to enhance your travel experience. Get information about local attractions, weather, transportation options, and more.
Browse thousands of different options on Cheapflights for your next trip
Toggle through the tabs below to find thousands of options on Cheapflights for your next trip.
Alternative routes
Complete your trip
Flights by cabin class
Other flight options
Popular flights
Top destinations
Alternative routes for Chicago to Missouri
See prices for flight routes from nearby airports that may be better suited for you.
Complete your trip
Complete your trip to Missouri by adding a car rental and/or hotel reservation to your travel itinerary.
Search flights from Chicago to Missouri by cabin class
Find flights from Chicago to Missouri, based on your preferred cabin class, be it economy, premium economy, business, or first class.
Chicago and Missouri flights
Browse other Chicago and Missouri flight options. Last updated on July 8, 2026.
Popular flight searches
Check out other popular destinations found by fellow travelers in 2026
Chicago to Missouri flights
Consider these flights traveling from Chicago to Missouri.
Top 5 airlines flying from Chicago to Missouri
Discover the top 5 airlines that operate flights from Chicago to Missouri. Compare their services, reliability, and customer satisfaction ratings to choose the airline that best suits your travel preferences and needs. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated July 8, 2026.
| Airline | Cheapest | Average | Flexibility | On-time |
|---|---|---|---|---|
| Cheapest$77 | Average$383 | FlexibilityNo cancel fee | On-time63% | |
| Cheapest$92 | Average$145 | FlexibilityNo cancel fee | On-timeN/A | |
| Cheapest$151 | Average$321 | FlexibilityNo cancel fee | On-time71% | |
| Cheapest$157 | Average$400 | FlexibilityNo cancel fee | On-time69% | |
| Cheapest$165 | Average$227 | FlexibilityNo cancel fee | On-timeN/A |