$59+ Cheap flights from Chicago (CHI) to Missouri
This is the cheapest round-trip flight price found by a Cheapflights user in the last 72 hours by searching for a flight departing on 10/22. Fares are subject to change and may not be available on all flights or dates of travel.
CHI — STL
Nov 6 — Nov 131
Round-trip
1 adult, Economy
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Find cheap flights from Chicago to Missouri with Cheapflights
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Enter your travel information like dates, passengers, trip type (one-way or round trip), and preferred cabin class then click “Find deals”2. Select your favorite providers
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Cheapest flights from Chicago to MissouriExplore the most affordable flight options available from Chicago to Missouri. Find the lowest fares from popular airlines and budget airlines, with prices last updated on October 7, 2026.
Explore the most affordable flight options available from Chicago to Missouri. Find the lowest fares from popular airlines and budget airlines, with prices last updated on October 7, 2026.
This Mytrip deal was found by Cheapflights users on 10/5. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Mytrip is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 10/212:55 pm -
Nonstop1h 30m
Sun 10/2512:30 pm -
Nonstop1h 45m
Deal found 10/5![Contour logo]()
$122
This Booking.com deal was found by Cheapflights users on 10/7. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Booking.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 10/292:55 pm -
Nonstop1h 30m
Thu 11/512:30 pm -
Nonstop1h 45m
Deal found 10/7![Contour logo]()
$123
This Kiwi.com deal was found by Cheapflights users on 10/4. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 10/232:55 pm -
Nonstop1h 30m
Sun 10/2512:30 pm -
Nonstop1h 45m
Deal found 10/4![Contour logo]()
$137
This Mytrip deal was found by Cheapflights users on 10/6. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Mytrip is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 11/202:55 pm -
Nonstop1h 30m
Fri 11/2712:30 pm -
Nonstop1h 45m
Deal found 10/6![Contour logo]()
$152
This Mytrip deal was found by Cheapflights users on 10/5. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Mytrip is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 11/192:55 pm -
Nonstop1h 30m
Sun 11/2212:30 pm -
Nonstop1h 45m
Deal found 10/5![Contour logo]()
$158
This Booking.com deal was found by Cheapflights users on 10/5. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Booking.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 10/152:55 pm -
Nonstop1h 30m
Thu 10/2212:30 pm -
Nonstop1h 45m
Deal found 10/5![Contour logo]()
$160
This Trip.com deal was found by Cheapflights users on 10/4. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Trip.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 11/202:55 pm -
Nonstop1h 30m
Sun 11/2212:30 pm -
Nonstop1h 45m
Deal found 10/4![Contour logo]()
$161
This Southwest deal was found by Cheapflights users on 10/5. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 11/215:50 pm -
Nonstop1h 15m
Sun 11/221:05 pm -
Nonstop1h 05m
Deal found 10/5![Southwest logo]()
$171
This American Airlines deal was found by Cheapflights users on 10/4. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 11/216:40 pm -
Nonstop1h 24m
Sun 11/228:12 pm -
Nonstop1h 36m
Deal found 10/4![American Airlines logo]()
$171
This Mytrip deal was found by Cheapflights users on 10/6. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Mytrip is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 11/511:15 am -
Nonstop1h 35m
Sun 11/89:40 am -
Nonstop1h 55m
Deal found 10/6![Contour logo]()
$179
This Booking.com deal was found by Cheapflights users on 10/4. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Booking.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 10/1911:15 am -
Nonstop1h 35m
Fri 10/239:40 am -
Nonstop1h 55m
Deal found 10/4![Contour logo]()
$183
This FlightHub deal was found by Cheapflights users on 10/6. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure FlightHub is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 11/511:15 am -
Nonstop1h 35m
Mon 11/99:40 am -
Nonstop1h 55m
Deal found 10/6![Contour logo]()
$187
Best flights from Chicago to MissouriDiscover carefully curated flight deals from Chicago to Missouri that have cost, travel time, and layovers in mind to ensure you get the best travel experience. Data last updated October 7, 2026.
Discover carefully curated flight deals from Chicago to Missouri that have cost, travel time, and layovers in mind to ensure you get the best travel experience. Data last updated October 7, 2026.
This Mytrip deal was found by Cheapflights users on 10/5. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Mytrip is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 10/212:55 pm -
Nonstop1h 30m
Sun 10/2512:30 pm -
Nonstop1h 45m
Deal found 10/5![Contour logo]()
$122
This Southwest deal was found by Cheapflights users on 10/3. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 11/213:10 pm -
1 stop3h 55m
Sun 11/221:05 pm -
Nonstop1h 05m
Deal found 10/3![Southwest logo]()
$181
This Delta deal was found by Cheapflights users on 10/3. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 11/219:59 am -
1 stop6h 42m
Sun 11/226:40 am -
1 stop3h 59m
Deal found 10/3![Delta logo]()
$191
This United Airlines deal was found by Cheapflights users on 10/3. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 10/317:44 am -
Nonstop2h 00m
Sat 11/76:01 am -
Nonstop1h 58m
Deal found 10/3![United Airlines logo]()
$241
This Booking.com deal was found by Cheapflights users on 10/7. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Booking.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 10/292:55 pm -
Nonstop1h 30m
Thu 11/512:30 pm -
Nonstop1h 45m
Deal found 10/7![Contour logo]()
$123
This Kiwi.com deal was found by Cheapflights users on 10/5. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 10/212:55 pm -
Nonstop1h 30m
Sun 10/255:10 pm -
3 stops43h 41m
Deal found 10/5![Multiple Airlines logo]()
$323
This Mytrip deal was found by Cheapflights users on 10/6. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Mytrip is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 11/202:55 pm -
Nonstop1h 30m
Fri 11/2712:30 pm -
Nonstop1h 45m
Deal found 10/6![Contour logo]()
$152
This American Airlines deal was found by Cheapflights users on 10/4. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 10/237:18 pm -
Nonstop1h 37m
Mon 10/266:25 pm -
Nonstop1h 46m
Deal found 10/4![American Airlines logo]()
$354
This Mytrip deal was found by Cheapflights users on 10/5. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Mytrip is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 11/192:55 pm -
Nonstop1h 30m
Sun 11/2212:30 pm -
Nonstop1h 45m
Deal found 10/5![Contour logo]()
$158
This Trip.com deal was found by Cheapflights users on 10/4. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Trip.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 11/202:55 pm -
Nonstop1h 30m
Sun 11/2212:30 pm -
Nonstop1h 45m
Deal found 10/4![Contour logo]()
$161
This United Airlines deal was found by Cheapflights users on 10/2. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 10/2410:15 am -
Nonstop1h 54m
Mon 10/266:01 am -
Nonstop1h 58m
Deal found 10/2![United Airlines logo]()
$241
This Southwest deal was found by Cheapflights users on 10/5. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 11/113:45 pm -
2 stops6h 25m
Sat 11/149:45 am -
Nonstop1h 25m
Deal found 10/5![Southwest logo]()
$255
This Mytrip deal was found by Cheapflights users on 10/6. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Mytrip is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 11/511:15 am -
Nonstop1h 35m
Sun 11/89:40 am -
Nonstop1h 55m
Deal found 10/6![Contour logo]()
$179
This United Airlines deal was found by Cheapflights users on 10/6. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 11/47:59 am -
Nonstop2h 00m
Wed 11/116:01 am -
Nonstop1h 58m
Deal found 10/6![United Airlines logo]()
$241
This Southwest deal was found by Cheapflights users on 10/5. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 10/2712:05 pm -
Nonstop1h 25m
Wed 10/282:40 pm -
Nonstop1h 20m
Deal found 10/5![Southwest logo]()
$264
This United Airlines deal was found by Cheapflights users on 10/6. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 11/141:00 pm -
Nonstop1h 34m
Sat 11/146:50 pm -
Nonstop1h 29m
Deal found 10/6![United Airlines logo]()
$243
This Booking.com deal was found by Cheapflights users on 10/4. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Booking.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 10/1911:15 am -
Nonstop1h 35m
Fri 10/239:40 am -
Nonstop1h 55m
Deal found 10/4![Contour logo]()
$183
This Delta deal was found by Cheapflights users on 10/2. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 12/910:36 am -
1 stop5h 59m
Sun 12/135:23 pm -
1 stop6h 33m
Deal found 10/2![Delta logo]()
$319
This United Airlines deal was found by Cheapflights users on 10/6. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 11/410:45 am -
Nonstop1h 25m
Wed 11/116:00 am -
Nonstop1h 36m
Deal found 10/6![United Airlines logo]()
$243
This Southwest deal was found by Cheapflights users on 10/2. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 11/146:35 am -
Nonstop1h 20m
Sat 11/144:20 pm -
Nonstop1h 05m
Deal found 10/2![Southwest logo]()
$279
This Contour deal was found by Cheapflights users on 10/6. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Contour is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 10/3011:15 am -
Nonstop1h 35m
Sat 10/319:40 am -
Nonstop1h 55m
Deal found 10/6![Contour logo]()
$198
This Delta deal was found by Cheapflights users on 10/2. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 10/315:27 am -
1 stop6h 39m
Sat 11/74:00 pm -
1 stop7h 57m
Deal found 10/2![Delta logo]()
$319
This Kiwi.com deal was found by Cheapflights users on 10/5. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 11/192:55 pm -
Nonstop1h 30m
Sun 11/225:10 pm -
1 stop25h 22m
Deal found 10/5![Multiple Airlines logo]()
$352
This Southwest deal was found by Cheapflights users on 10/2. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 10/304:15 pm -
1 stop4h 40m
Fri 11/69:35 pm -
Nonstop1h 10m
Deal found 10/2![Southwest logo]()
$289
This Contour deal was found by Cheapflights users on 10/2. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Contour is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 10/1711:15 am -
Nonstop1h 35m
Wed 10/219:40 am -
Nonstop1h 55m
Deal found 10/2![Contour logo]()
$198
This Kiwi.com deal was found by Cheapflights users on 10/3. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 10/186:20 am -
1 stop29h 05m
Thu 10/2212:30 pm -
Nonstop1h 45m
Deal found 10/3![Multiple Airlines logo]()
$364
This United Airlines deal was found by Cheapflights users on 10/6. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 10/2610:45 am -
Nonstop1h 25m
Fri 10/305:00 am -
Nonstop1h 29m
Deal found 10/6![United Airlines logo]()
$279
This Delta deal was found by Cheapflights users on 10/6. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 11/110:12 am -
1 stop6h 18m
Wed 11/1112:35 pm -
1 stop4h 04m
Deal found 10/6![Delta logo]()
$343
This Contour deal was found by Cheapflights users on 10/6. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Contour is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 10/2111:15 am -
Nonstop1h 35m
Sun 10/259:40 am -
Nonstop1h 55m
Deal found 10/6![Contour logo]()
$198
This American Airlines deal was found by Cheapflights users on 10/3. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 10/227:18 pm -
Nonstop1h 37m
Sat 10/245:14 pm -
1 stop6h 45m
Deal found 10/3![American Airlines logo]()
$447
Last-minute flights from Chicago to MissouriDiscover last-minute flight deals from Chicago to Missouri. Data last updated October 7, 2026 and is based on user searches.
Discover last-minute flight deals from Chicago to Missouri. Data last updated October 7, 2026 and is based on user searches.
This Booking.com deal was found by Cheapflights users on 10/5. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Booking.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 10/152:55 pm -
Nonstop1h 30m
Thu 10/2212:30 pm -
Nonstop1h 45m
Deal found 10/5![Contour logo]()
$160
This Booking.com deal was found by Cheapflights users on 10/4. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Booking.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 10/1911:15 am -
Nonstop1h 35m
Fri 10/239:40 am -
Nonstop1h 55m
Deal found 10/4![Contour logo]()
$183
This Mytrip deal was found by Cheapflights users on 10/5. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Mytrip is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 10/212:55 pm -
Nonstop1h 30m
Sun 10/2512:30 pm -
Nonstop1h 45m
Deal found 10/5![Contour logo]()
$122
This Kiwi.com deal was found by Cheapflights users on 10/4. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 10/232:55 pm -
Nonstop1h 30m
Sun 10/2512:30 pm -
Nonstop1h 45m
Deal found 10/4![Contour logo]()
$137
This Booking.com deal was found by Cheapflights users on 10/7. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Booking.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 10/292:55 pm -
Nonstop1h 30m
Thu 11/512:30 pm -
Nonstop1h 45m
Deal found 10/7![Contour logo]()
$123
This Mytrip deal was found by Cheapflights users on 10/6. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Mytrip is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 11/511:15 am -
Nonstop1h 35m
Sun 11/89:40 am -
Nonstop1h 55m
Deal found 10/6![Contour logo]()
$179
This FlightHub deal was found by Cheapflights users on 10/6. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure FlightHub is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 11/511:15 am -
Nonstop1h 35m
Mon 11/99:40 am -
Nonstop1h 55m
Deal found 10/6![Contour logo]()
$187
This Mytrip deal was found by Cheapflights users on 10/5. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Mytrip is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 11/192:55 pm -
Nonstop1h 30m
Sun 11/2212:30 pm -
Nonstop1h 45m
Deal found 10/5![Contour logo]()
$158
This Mytrip deal was found by Cheapflights users on 10/6. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Mytrip is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 11/202:55 pm -
Nonstop1h 30m
Fri 11/2712:30 pm -
Nonstop1h 45m
Deal found 10/6![Contour logo]()
$152
This Trip.com deal was found by Cheapflights users on 10/4. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Trip.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 11/202:55 pm -
Nonstop1h 30m
Sun 11/2212:30 pm -
Nonstop1h 45m
Deal found 10/4![Contour logo]()
$161
This Southwest deal was found by Cheapflights users on 10/5. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 11/215:50 pm -
Nonstop1h 15m
Sun 11/221:05 pm -
Nonstop1h 05m
Deal found 10/5![Southwest logo]()
$171
This American Airlines deal was found by Cheapflights users on 10/4. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 11/216:40 pm -
Nonstop1h 24m
Sun 11/228:12 pm -
Nonstop1h 36m
Deal found 10/4![American Airlines logo]()
$171
One-way flights from Chicago to MissouriSearch for one-way flight options from Chicago to Missouri. Find affordable one-way fares based on user searches. Data last updated October 7, 2026.
Search for one-way flight options from Chicago to Missouri. Find affordable one-way fares based on user searches. Data last updated October 7, 2026.
This Booking.com deal was found by Cheapflights users on 10/2. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Booking.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 10/222:55 pm -
Nonstop1h 30m
Wed 12/3112:00 am -
Nonstop0h 00m
Deal found 10/2![Contour logo]()
$59
This Frontier deal was found by Cheapflights users on 10/5. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Frontier is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 10/286:30 am -
1 stop8h 53m
Wed 12/3112:00 am -
Nonstop0h 00m
Deal found 10/5![Frontier logo]()
$59
This Super.com deal was found by Cheapflights users on 10/5. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Super.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 10/266:20 am -
1 stop10h 38m
Wed 12/3112:00 am -
Nonstop0h 00m
Deal found 10/5![Frontier logo]()
$64
This Frontier deal was found by Cheapflights users on 10/6. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Frontier is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 11/46:16 am -
1 stop11h 24m
Wed 12/3112:00 am -
Nonstop0h 00m
Deal found 10/6![Frontier logo]()
$65
This Trip.com deal was found by Cheapflights users on 10/5. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Trip.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 10/286:16 am -
1 stop11h 24m
Wed 12/3112:00 am -
Nonstop0h 00m
Deal found 10/5![Frontier logo]()
$66
This Booking.com deal was found by Cheapflights users on 10/3. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Booking.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 11/82:55 pm -
Nonstop1h 30m
Wed 12/3112:00 am -
Nonstop0h 00m
Deal found 10/3![Contour logo]()
$73
This Mytrip deal was found by Cheapflights users on 10/3. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Mytrip is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 11/122:55 pm -
Nonstop1h 30m
Wed 12/3112:00 am -
Nonstop0h 00m
Deal found 10/3![Contour logo]()
$76
This Kiwi.com deal was found by Cheapflights users on 10/6. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 11/187:35 pm -
1 stop23h 04m
Wed 12/3112:00 am -
Nonstop0h 00m
Deal found 10/6![Frontier logo]()
$77
This Super.com deal was found by Cheapflights users on 10/6. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Super.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 10/306:30 am -
1 stop12h 44m
Wed 12/3112:00 am -
Nonstop0h 00m
Deal found 10/6![Frontier logo]()
$81
This Frontier deal was found by Cheapflights users on 10/6. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Frontier is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 11/66:08 am -
1 stop11h 34m
Wed 12/3112:00 am -
Nonstop0h 00m
Deal found 10/6![Frontier logo]()
$82
This Frontier deal was found by Cheapflights users on 10/6. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Frontier is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 11/66:30 am -
1 stop12h 44m
Wed 12/3112:00 am -
Nonstop0h 00m
Deal found 10/6![Frontier logo]()
$82
This Trip.com deal was found by Cheapflights users on 10/2. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Trip.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 11/177:35 pm -
1 stop22h 07m
Wed 12/3112:00 am -
Nonstop0h 00m
Deal found 10/2![Frontier logo]()
$83
Find flight deals from Chicago to Missouri
Keep the following information in mind while searching for Chicago to Missouri flight deals. Data was last updated October 7, 2026.
Most accurate provider | FlightHub 3 stars |
|---|---|
Most trusted provider | FlightHub 3 stars |
Round-trip from | $122 (Mytrip) |
One-way from | $59 (Booking.com) |
Popular in | April |
Cheapest in | December |
Average price | $432 |
Good round-trip deal | $138 or less |
Good one-way deal | $86 or less |
Cheapflights Fare Finder
Customize your flight search to find flights from Chicago to Missouri that fit within your specific budget. Explore options based on user searches and filter the results based on your desired price range. Find flights that match your budget for a cost-effective journey. Over the last 7 days, Cheapflights users made 7,457,451 searches. Data last updated October 7, 2026.
Use the filters below to find and compare flights from Chicago to Missouri that are best for you.
Fly from
Fly to
Route
Depart
Return
Cheapest round-trip
ChicagoKirksville
ORD Chicago O'Hare Intl - IRK Kirksville Cannon Memorial
ORDIRK
Chicago O'Hare Intl
Thu 10/22
2:55 pm-4:25 pm
Nonstop1h 30m
Kirksville Cannon Memorial
Wed 12/31
12:00 am-12:00 am
Nonstop0h 00m
$59
ChicagoKirksville
ORD Chicago O'Hare Intl - IRK Kirksville Cannon Memorial
ORDIRK
Chicago O'Hare Intl
Sun 11/8
2:55 pm-4:25 pm
Nonstop1h 30m
Kirksville Cannon Memorial
Wed 12/31
12:00 am-12:00 am
Nonstop0h 00m
$73
ChicagoKirksville
ORD Chicago O'Hare Intl - IRK Kirksville Cannon Memorial
ORDIRK
Chicago O'Hare Intl
Thu 11/12
2:55 pm-4:25 pm
Nonstop1h 30m
Kirksville Cannon Memorial
Wed 12/31
12:00 am-12:00 am
Nonstop0h 00m
$76
ChicagoKirksville
ORD Chicago O'Hare Intl - IRK Kirksville Cannon Memorial
ORDIRK
Chicago O'Hare Intl
Thu 10/15
2:55 pm-4:25 pm
Nonstop1h 30m
Kirksville Cannon Memorial
Wed 12/31
12:00 am-12:00 am
Nonstop0h 00m
$93
ChicagoSt. Louis
MDW Chicago Midway - STL Lambert-St Louis
MDWSTL
Chicago Midway
Tue 12/22
12:05 pm-3:25 pm
1 stop3h 20m
Lambert-St Louis
Wed 12/31
12:00 am-12:00 am
Nonstop0h 00m
$96
ChicagoSt. Louis
ORD Chicago O'Hare Intl - STL Lambert-St Louis
ORDSTL
Chicago O'Hare Intl
Thu 12/31
6:23 am-10:35 am
1 stop4h 12m
Lambert-St Louis
Wed 12/31
12:00 am-12:00 am
Nonstop0h 00m
$96
ChicagoCape Girardeau
ORD Chicago O'Hare Intl - CGI Cape Girardeau
ORDCGI
Chicago O'Hare Intl
Wed 10/21
11:15 am-12:50 pm
Nonstop1h 35m
Cape Girardeau
Wed 12/31
12:00 am-12:00 am
Nonstop0h 00m
$99
ChicagoKirksville
ORD Chicago O'Hare Intl - IRK Kirksville Cannon Memorial
ORDIRK
Chicago O'Hare Intl
Sun 10/25
2:55 pm-4:25 pm
Nonstop1h 30m
Kirksville Cannon Memorial
Wed 12/31
12:00 am-12:00 am
Nonstop0h 00m
$117
ChicagoCape Girardeau
ORD Chicago O'Hare Intl - CGI Cape Girardeau
ORDCGI
Chicago O'Hare Intl
Mon 1/11
11:15 am-12:50 pm
Nonstop1h 35m
Cape Girardeau
Wed 12/31
12:00 am-12:00 am
Nonstop0h 00m
$119
ChicagoCape Girardeau
ORD Chicago O'Hare Intl - CGI Cape Girardeau
ORDCGI
Chicago O'Hare Intl
Tue 12/1
11:15 am-12:50 pm
Nonstop1h 35m
Cape Girardeau
Wed 12/31
12:00 am-12:00 am
Nonstop0h 00m
$119
Showing 1-10 of 60 resultsSorted by cheapest first
Best time to book a flight from Chicago to Missouri
Have a flexible travel schedule? Discover the best time to fly to Missouri from Chicago with our price prediction graph.
ORD-IRK
MDW-STL
ORD-STL
ORD-CGI
ORD-MCI
Estimated round-trip price
Rates are based on past data. Find the cheapest month and day to book your flight based on your travel requirements, then search for cheap deals.
Cheapflights Insights
Everything you need to know about your flight from Chicago to Missouri
CHI-USMO
ORD-IRK
MDW-STL
ORD-STL
ORD-CGI
What is the cheapest month to book a flight from Chicago to Missouri?
Currently, December is the cheapest month in which you can book a flight from Chicago to Missouri (average of $315). Flying from Chicago to Missouri in June is currently the most expensive (average of $458). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.
What is the cheapest time of day to fly from CHI to MO?
Find hourly flight availability from Chicago to Missouri. Discover flight options and departure times throughout the day, allowing you to choose a departure time that suits your schedule. Data last updated October 7, 2026.
It’s optimal to fly from Chicago to Missouri in the morning. By choosing this option you can save up to 14% on the cost of your flight, compared to a flight in the evening.
Weekly flight availability from Chicago to Missouri
Explore weekly flight availability from Chicago to Missouri. Discover flights operating on different days of the week, giving you the flexibility to choose a travel day that best fits your plans. Compare info to find the most convenient option for your journey. Data last updated October 7, 2026.
The most flights from CHI to USMO are scheduled on a Monday (67 on average). You will have fewer flight options on Saturday, which is when the least amount of flights are scheduled (21 on average).
How much does it cost to fly round-trip from Chicago to Missouri?
Airfare is below average for this route at the moment.
Chicago to Missouri flights typically cost between $269 and $581 in November.The cheapest round-trip price found within the last 5 days was $171 on Southwest (Nov 21-Nov 22).
How far ahead should I book a flight from Chicago to Missouri?
To ensure you get the cheapest price possible for a flight from Chicago to Missouri, you should look to book at least 84 days in advance of your intended travel date. The price of your flight may increase if you delay and leave booking until a week or so before departure.
What is the cheapest day to fly from Chicago to Missouri?
Use this chart to determine the cheapest time to fly round-trip from Chicago to Missouri. Price data was last updated on October 3, 2026.
Travelers seeking maximum savings on their Chicago to Missouri flight should consider departing on Saturday mornings when fares are most often at their lowest. Tuesday evenings flights should be avoided if possible as fares are typically the most expensive at this time.
Reviews of airlines servicing Missouri
Get insights into the airlines that provide service to Missouri. Read reviews, discover amenities, and learn about the overall travel experience offered by airlines. Use this information to make informed decisions when choosing an airline for your flight to Missouri. Reviews last updated October 7, 2026.
Get a feel of what it's like to fly with Southwest,Contour, andUnited Airlines from Chicago to Missouri by reading reviews from past customers. You can also see how each airline compares in terms of entertainment options, comfort, food, crew/service, and boarding process.
Entertainment
7.5
Boarding
8.1
Crew
8.6
Food
7.0
Comfort
8.0
Overall
7.9
Reviews
1 / 20
10.0
ExcellentCourtney,Sep 2026
DEN - STL
Entertainment
7.5
Boarding
8.1
Crew
8.6
Food
7.0
Comfort
8.0
Overall
7.9
Reviews
1 / 20
10.0
ExcellentCourtney,Sep 2026
DEN - STL
Entertainment
7.5
Boarding
8.1
Crew
8.6
Food
7.0
Comfort
8.0
Overall
7.9
Reviews
1 / 20
10.0
ExcellentCourtney,Sep 2026
DEN - STL
Entertainment
7.5
Boarding
8.1
Crew
8.6
Food
7.0
Comfort
8.0
Overall
7.9
Reviews
1 / 20
10.0
ExcellentCourtney,Sep 2026
DEN - STL
Entertainment
7.5
Boarding
8.1
Crew
8.6
Food
7.0
Comfort
8.0
Overall
7.9
Reviews
1 / 20
10.0
ExcellentCourtney,Sep 2026
DEN - STL
Entertainment
7.5
Boarding
8.1
Crew
8.6
Food
7.0
Comfort
8.0
Overall
7.9
Reviews
1 / 20
10.0
ExcellentCourtney,Sep 2026
DEN - STL
Related info for your journey
Find useful and relevant information for your journey from Chicago to Missouri. Access travel guides, tips, and recommendations to enhance your travel experience. Get information about local attractions, weather, transportation options, and more.
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Alternative routes for Chicago to Missouri
See prices for flight routes from nearby airports that may be better suited for you.
Complete your trip
Complete your trip to Missouri by adding a car rental and/or hotel reservation to your travel itinerary.
Search flights from Chicago to Missouri by cabin class
Find flights from Chicago to Missouri, based on your preferred cabin class, be it economy, premium economy, business, or first class.
Chicago and Missouri flights
Browse other Chicago and Missouri flight options. Last updated on October 7, 2026.
Popular flight searches
Check out other popular destinations found by fellow travelers in 2026
Chicago to Missouri flights
Consider these flights traveling from Chicago to Missouri.
Top 4 airlines flying from Chicago to Missouri
Discover the top 4 airlines that operate flights from Chicago to Missouri. Compare their services, reliability, and customer satisfaction ratings to choose the airline that best suits your travel preferences and needs. Over the last 7 days, Cheapflights users made 7,457,451 searches. Data last updated October 7, 2026.
| Airline | Cheapest | Average | Flexibility | On-time |
|---|---|---|---|---|
| Cheapest$104 | Average$153 | FlexibilityNo cancel fee | On-timeN/A | |
| Cheapest$151 | Average$336 | FlexibilityNo cancel fee | On-time71% | |
| Cheapest$178 | Average$441 | FlexibilityNo cancel fee | On-time69% | |
| Cheapest$204 | Average$476 | FlexibilityNo cancel fee | On-time63% |