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Missouri

$96+ Cheap flights from Buffalo (BUF) to Missouri

This is the cheapest one-way flight price found by a Cheapflights user in the last 72 hours by searching for a flight departing on 1/29. Fares are subject to change and may not be available on all flights or dates of travel.
BUF — MCI
Jan 14 — Jan 211
Wed 1/14
Wed 1/21
1 adult, Economy
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Cheap flight deals from Buffalo to Missouri

Cheapest flights from Buffalo to Missouri
Explore the most affordable flight options available from Buffalo to Missouri. Find the lowest fares from popular airlines and budget airlines, with prices last updated on December 15, 2025.

This American Airlines deal was found by Cheapflights users on 12/14. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 12/2612:32 pmBUF - SGF
1 stop5h 56mAmerican Airlines
Mon 12/293:42 pmSGF - BUF
1 stop6h 02mAmerican Airlines
Deal found 12/14$379
This Delta deal was found by Cheapflights users on 12/14. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 12/265:52 pmBUF - STL
1 stop3h 49mDelta
Thu 1/15:55 pmSTL - BUF
1 stop3h 38mDelta
Deal found 12/14$400
This United Airlines deal was found by Cheapflights users on 12/14. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 12/266:30 amBUF - SGF
1 stop5h 19mUnited Airlines
Tue 12/303:14 pmSGF - BUF
1 stop4h 40mUnited Airlines
Deal found 12/14$424
This American Airlines deal was found by Cheapflights users on 12/14. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 12/307:21 pmBUF - STL
1 stop5h 34mAmerican Airlines
Sat 1/35:22 amSTL - BUF
1 stop4h 45mAmerican Airlines
Deal found 12/14$447
This American Airlines deal was found by Cheapflights users on 12/14. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 12/307:21 pmBUF - MCI
1 stop5h 32mAmerican Airlines
Sat 1/36:13 amMCI - BUF
1 stop4h 58mAmerican Airlines
Deal found 12/14$467
This American Airlines deal was found by Cheapflights users on 12/13. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 12/2612:32 pmBUF - SGF
1 stop5h 56mAmerican Airlines
Tue 12/307:06 amSGF - BUF
1 stop8h 23mAmerican Airlines
Deal found 12/13$480
This Southwest deal was found by Cheapflights users on 12/14. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 12/305:00 amBUF - MCI
2 stops10h 55mSouthwest
Sat 1/35:30 amMCI - BUF
1 stop6h 00mSouthwest
Deal found 12/14$482
This Delta deal was found by Cheapflights users on 12/14. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 12/265:52 pmBUF - STL
1 stop3h 49mDelta
Mon 1/56:00 amSTL - BUF
1 stop5h 59mDelta
Deal found 12/14$482
This Delta deal was found by Cheapflights users on 12/14. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 12/167:00 amBUF - STL
1 stop10h 35mDelta
Sun 1/45:13 pmSTL - BUF
1 stop5h 37mDelta
Deal found 12/14$485
This Southwest deal was found by Cheapflights users on 12/14. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 12/268:40 pmBUF - STL
1 stop4h 25mSouthwest
Mon 1/57:40 amSTL - BUF
2 stops13h 30mSouthwest
Deal found 12/14$523
This Kiwi.com deal was found by Cheapflights users on 12/13. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 12/153:18 pmBUF - MCI
1 stop8h 57mMultiple Airlines
Sat 12/206:15 pmMCI - BUF
2 stops22h 22mMultiple Airlines
Deal found 12/13$533
This Southwest deal was found by Cheapflights users on 12/14. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 12/278:50 pmBUF - STL
1 stop4h 25mSouthwest
Mon 12/295:45 amSTL - BUF
1 stop5h 05mSouthwest
Deal found 12/14$534

Find flight deals from Buffalo to Missouri

Keep the following information in mind while searching for Buffalo to Missouri flight deals. Data was last updated December 15, 2025.

Most accurate provider

eDreams
3 stars

Most trusted provider

eDreams
3 stars

Round-trip from

$219
(Kiwi.com)

One-way from

$96
(Kiwi.com)

Popular in

January

Cheapest in

September

Average price

$396
Provider with most accurate pricing for Buffalo-Lambert-St Louis flight deals.
Search Deals
Provider most trusted by Cheapflights users for Buffalo-Lambert-St Louis flights.
Search Deals
From Buffalo to Missouri
Search Deals
One-way flight from Buffalo to Missouri
Search Deals
Highest demand for flights based on searches. 9% potential increase in price ($39 potential increase over avg. RT price).
Search Deals
Cheapest flight prices on average. 1% potential price decrease ($6 potential savings vs. average RT price).
Search Deals
Average for round-trip flights in December 2025
Search Deals

Cheapflights Fare Finder

 
Customize your flight search to find flights from Buffalo to Missouri that fit within your specific budget. Explore options based on user searches and filter the results based on your desired price range. Find flights that match your budget for a cost-effective journey. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated December 15, 2025.
Use the filters below to find and compare flights from Buffalo to Missouri that are best for you.

Fly from

Buffalo

Fly to

Missouri

Route

Depart

Return

Price

BuffaloSt. Louis

BUF - STL

BUFSTL

Buffalo

Sun 1/18

6:00 am-11:05 am

1 stop6h 05m

Lambert-St Louis

Tue 1/20

6:35 am-11:45 am

1 stop4h 10m

$223

BuffaloKansas City

BUF - MCI

BUFMCI

Buffalo

Sun 1/4

1:37 pm-10:59 pm

1 stop10h 22m

Kansas City

Sun 1/11

8:59 am-12:00 pm

2 stops26h 01m

$278

BuffaloSt. Louis

BUF - STL

BUFSTL

Buffalo

Sun 1/18

8:00 am-3:04 pm

2 stops8h 04m

Lambert-St Louis

Tue 1/20

6:46 pm-11:48 pm

1 stop4h 02m

$282

BuffaloSt. Louis

BUF - STL

BUFSTL

Buffalo

Fri 3/6

9:25 pm-7:07 am

1 stop10h 42m

Lambert-St Louis

Sun 3/8

7:42 am-8:30 pm

1 stop11h 48m

$282

BuffaloSt. Louis

BUF - STL

BUFSTL

Buffalo

Thu 4/9

11:42 am-10:33 pm

1 stop11h 51m

Lambert-St Louis

Sun 4/12

10:42 am-12:42 pm

1 stop25h 00m

$285

BuffaloKansas City

BUF - MCI

BUFMCI

Buffalo

Sun 1/4

1:37 pm-10:59 pm

1 stop10h 22m

Kansas City

Fri 1/9

11:26 am-12:00 pm

2 stops47h 34m

$289

BuffaloKansas City

BUF - MCI

BUFMCI

Buffalo

Sat 1/10

6:00 am-12:42 pm

1 stop7h 42m

Kansas City

Sat 1/17

4:01 pm-11:56 pm

1 stop6h 55m

$293

BuffaloSt. Louis

BUF - STL

BUFSTL

Buffalo

Sun 1/11

6:03 am-9:39 am

1 stop4h 36m

Lambert-St Louis

Tue 1/13

6:25 am-2:10 pm

1 stop6h 45m

$312

BuffaloKansas City

BUF - MCI

BUFMCI

Buffalo

Sat 2/21

8:25 am-4:19 pm

1 stop8h 54m

Kansas City

Tue 2/24

5:30 pm-11:44 pm

1 stop5h 14m

$317

BuffaloKansas City

BUF - MCI

BUFMCI

Buffalo

Tue 1/6

5:23 pm-9:59 pm

1 stop5h 36m

Kansas City

Sat 1/10

8:00 am-1:24 pm

1 stop4h 24m

$317

Flights are sorted by cheapest round-trip flights first.

Deals found on 12/14

Showing 1-10 of 34 results
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Best time to book a flight from Buffalo to Missouri

Have a flexible travel schedule? Discover the best time to fly to Missouri from Buffalo with our price prediction graph.
Estimated round-trip price
Rates are based on past data. Find the cheapest month and day to book your flight based on your travel requirements, then search for cheap deals.

Cheapflights Insights

Everything you need to know about your flight from Buffalo to Missouri

What is the cheapest month to book a flight from Buffalo to Missouri?

Currently, August is the cheapest month in which you can book a flight from Buffalo to Missouri (average of $112). Flying from Buffalo to Missouri in May is currently the most expensive (average of $274). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.

What is the cheapest time of day to fly from BUF to MO?

Find hourly flight availability from Buffalo to Missouri. Discover flight options and departure times throughout the day, allowing you to choose a departure time that suits your schedule. Data last updated December 15, 2025.

Unlike in the morning, when flights are generally more expensive, you can save up to 23% on flights from Buffalo to Missouri by exploring options for tickets in the evening.

Reviews of airlines servicing Missouri

Get insights into the airlines that provide service to Missouri. Read reviews, discover amenities, and learn about the overall travel experience offered by airlines. Use this information to make informed decisions when choosing an airline for your flight to Missouri. Reviews last updated December 15, 2025.
Read through reviews of airlines operating flights from Buffalo to Missouri, such as Southwest, Delta, and United Airlines. You can also see how each airline stacks up in terms of entertainment options, comfort, food, crew/service, and boarding process.
Southwest
7.9
Good
4,250 reviews

Entertainment

7.5

Food

7.0

Crew

8.6

Boarding

8.1

Comfort

8.0

Overall

7.9

Reviews

1 / 20
2.0
Mediocre

Thomas,Dec 2025

SEA - DEN

Plane two hours late in leaving 1:00 pm west coat time got home next day at 2:45am most car rental places are closed and don’t open till 5am
Southwest
7.9
Good
4,250 reviews
Southwest
7.9
Good
4,250 reviews

Entertainment

7.5

Food

7.0

Crew

8.6

Boarding

8.1

Comfort

8.0

Overall

7.9

Reviews

1 / 20
2.0
Mediocre

Thomas,Dec 2025

SEA - DEN

Plane two hours late in leaving 1:00 pm west coat time got home next day at 2:45am most car rental places are closed and don’t open till 5am
Delta
7.9
Good
8,007 reviews
Southwest
7.9
Good
4,250 reviews

Entertainment

7.5

Food

7.0

Crew

8.6

Boarding

8.1

Comfort

8.0

Overall

7.9

Reviews

1 / 20
2.0
Mediocre

Thomas,Dec 2025

SEA - DEN

Plane two hours late in leaving 1:00 pm west coat time got home next day at 2:45am most car rental places are closed and don’t open till 5am
United Airlines
7.4
Good
9,092 reviews
Southwest
7.9
Good
4,250 reviews

Entertainment

7.5

Food

7.0

Crew

8.6

Boarding

8.1

Comfort

8.0

Overall

7.9

Reviews

1 / 20
2.0
Mediocre

Thomas,Dec 2025

SEA - DEN

Plane two hours late in leaving 1:00 pm west coat time got home next day at 2:45am most car rental places are closed and don’t open till 5am
American Airlines
7.2
Good
11,052 reviews
Southwest
7.9
Good
4,250 reviews

Entertainment

7.5

Food

7.0

Crew

8.6

Boarding

8.1

Comfort

8.0

Overall

7.9

Reviews

1 / 20
2.0
Mediocre

Thomas,Dec 2025

SEA - DEN

Plane two hours late in leaving 1:00 pm west coat time got home next day at 2:45am most car rental places are closed and don’t open till 5am

Related info for your journey

Find useful and relevant information for your journey from Buffalo to Missouri. Access travel guides, tips, and recommendations to enhance your travel experience. Get information about local attractions, weather, transportation options, and more.

  • What airport do you fly from for flights from Buffalo to Missouri?

    Buffalo (BUF), located 8.3 mi from the city center, is the airport you fly out of when you book flights from Buffalo to Missouri.

  • How long is the flight from Buffalo to Missouri?

    A quick flight from Buffalo to Missouri can take about 6h 05m. Delta provides one of the quickest options available for as low as $223. Buffalo and Missouri are separated by a distance of 672 mi. This flight may include one or multiple stops.

  • What are the cheapest airlines to fly from Buffalo to Missouri one-way?

    To fly one-way, consider booking your trip with American Airlines, which is currently one of the cheapest options available, starting at $95. United Airlines flights start at $99 while deals on Delta start at $118 one-way.

  • What are the most popular routes from Buffalo to Missouri?

    While some choose either Buffalo - Lambert-St Louis or Buffalo - Springfield-Branson, Buffalo - Kansas City is the most popular route from Buffalo to Missouri.

  • Can I find deals for flights from Buffalo to Missouri that include hotel bookings?

    Yes. In addition to deals on Buffalo to Missouri flights, Cheapflights offers vacation packages that include both flights and hotel.

  • How can I find direct flights from Buffalo to Missouri?

    After entering your origin and destination, apply the non-stop filter on the search result page to find direct flights from Buffalo to Missouri.

  • Can I find deals for business class flights from Buffalo to Missouri?

    Yes. Cheapflights offers flight deals from Buffalo to Missouri by cabin class. In addition to browsing deals, you can also filter by cabin class on the search results page after making a search.

  • What is the cheapest month to book a flight from Buffalo to Missouri?

    Currently, August is the cheapest month in which you can book a flight from Buffalo to Missouri (average of $112). Flying from Buffalo to Missouri in May is currently the most expensive (average of $274). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.

See more FAQs

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Top 4 airlines flying from Buffalo to Missouri

Discover the top 4 airlines that operate flights from Buffalo to Missouri. Compare their services, reliability, and customer satisfaction ratings to choose the airline that best suits your travel preferences and needs. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated December 15, 2025.
AirlineCheapestAverageFlexibilityOn-time
DeltaCheapest$164Average$356FlexibilityNo cancel feeOn-timeN/A
United AirlinesCheapest$198Average$558FlexibilityNo cancel feeOn-time69%
American AirlinesCheapest$217Average$376FlexibilityNo cancel feeOn-time71%
SouthwestCheapest$236Average$399FlexibilityNo cancel feeOn-time63%

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