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$117+ Cheap flights from Buffalo (BUF) to Missouri

This is the cheapest one-way flight price found by a Cheapflights user in the last 72 hours by searching for a flight departing on 9/1. Fares are subject to change and may not be available on all flights or dates of travel.
BUF — STL
Aug 3 — Aug 101
Sun 8/3
Sun 8/10
1 adult, Economy
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Cheap flight deals from Buffalo to Missouri

Keep the following information in mind while searching for Buffalo to Missouri flight deals. Data was last updated July 29, 2025.

Round-trip from

$225
(FlightHub)

One-way from

$117
(FlightHub)

Popular in

January

Cheapest in

September

Average price

$400
From Buffalo to Missouri
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One-way flight from Buffalo to Missouri
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Highest demand for flights based on searches. 20% potential increase in price ($111 potential increase over avg. RT price).
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Cheapest flight prices on average. 10% potential price decrease ($42 potential savings vs. average RT price).
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Average for round-trip flights in July 2025
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Find flight deals from Buffalo to Missouri

Cheapest flights from Buffalo to Missouri
Explore the most affordable flight options available from Buffalo to Missouri. Find the lowest fares from popular airlines and budget airlines, with prices last updated on July 29, 2025.

This FlightHub deal was found by Cheapflights users on 7/27. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure FlightHub is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 8/12:11 pmBUF - STL
1 stop20h 00mFrontier
Sun 8/312:02 pmSTL - BUF
1 stop18h 25mFrontier
Deal found 7/27$225
This Delta deal was found by Cheapflights users on 7/28. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 9/136:30 pmBUF - MCI
1 stop4h 37mDelta
Tue 9/165:45 pmMCI - BUF
1 stop4h 11mDelta
Deal found 7/28$237
This American Airlines deal was found by Cheapflights users on 7/28. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 10/221:14 pmBUF - STL
1 stop6h 32mAmerican Airlines
Sat 10/254:34 pmSTL - BUF
1 stop6h 01mAmerican Airlines
Deal found 7/28$237
This Southwest deal was found by Cheapflights users on 7/28. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 8/278:50 amBUF - MCI
1 stop9h 50mSouthwest
Wed 9/39:00 amMCI - BUF
2 stops7h 55mSouthwest
Deal found 7/28$242
This Southwest deal was found by Cheapflights users on 7/28. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 10/224:15 pmBUF - STL
2 stops6h 50mSouthwest
Sat 10/253:35 pmSTL - BUF
1 stop6h 15mSouthwest
Deal found 7/28$242
This FlightHub deal was found by Cheapflights users on 7/29. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure FlightHub is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 10/2412:44 pmBUF - MCI
1 stop27h 44mFrontier
Sun 10/267:51 pmMCI - BUF
1 stop16h 23mFrontier
Deal found 7/29$248
This American Airlines deal was found by Cheapflights users on 7/29. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 10/255:27 pmBUF - MCI
1 stop4h 44mAmerican Airlines
Mon 10/273:03 pmMCI - BUF
1 stop6h 25mAmerican Airlines
Deal found 7/29$252
This American Airlines deal was found by Cheapflights users on 7/28. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 11/74:26 pmBUF - SGF
1 stop5h 43mAmerican Airlines
Mon 11/103:19 pmSGF - BUF
1 stop7h 17mAmerican Airlines
Deal found 7/28$277
This Delta deal was found by Cheapflights users on 7/27. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 9/2211:10 amBUF - SGF
2 stops7h 45mDelta
Sat 9/274:13 pmSGF - BUF
1 stop6h 24mDelta
Deal found 7/27$374
This United Airlines deal was found by Cheapflights users on 7/28. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 10/278:04 amBUF - MCI
1 stop9h 01mUnited Airlines
Tue 10/288:00 amMCI - BUF
2 stops9h 46mUnited Airlines
Deal found 7/28$375
This United Airlines deal was found by Cheapflights users on 7/27. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 9/2210:36 amBUF - SGF
2 stops14h 03mUnited Airlines
Sat 9/2711:25 amSGF - BUF
2 stops10h 10mUnited Airlines
Deal found 7/27$488
This United Airlines deal was found by Cheapflights users on 7/28. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 8/127:00 amBUF - STL
1 stop6h 27mUnited Airlines
Sat 8/166:33 amSTL - BUF
2 stops6h 39mUnited Airlines
Deal found 7/28$518

Cheapflights Fare Finder

 
Customize your flight search to find flights from Buffalo to Missouri that fit within your specific budget. Explore options based on user searches and filter the results based on your desired price range. Find flights that match your budget for a cost-effective journey. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated July 29, 2025.
Use the filters below to find and compare flights from Buffalo to Missouri that are best for you.

Fly from

Buffalo

Fly to

Missouri

Route

Depart

Return

Price

BuffaloSt. Louis

BUF - STL

BUFSTL

Buffalo

Thu 9/4

7:41 pm-1:02 pm

1 stop18h 21m

Lambert-St Louis

Sun 9/7

1:52 pm-6:14 pm

1 stop27h 22m

$225

BuffaloKansas City

BUF - MCI

BUFMCI

Buffalo

Sat 9/13

6:30 pm-10:07 pm

1 stop4h 37m

Kansas City

Tue 9/16

5:45 pm-10:56 pm

1 stop4h 11m

$237

BuffaloSt. Louis

BUF - STL

BUFSTL

Buffalo

Wed 10/22

1:14 pm-6:46 pm

1 stop6h 32m

Lambert-St Louis

Sat 10/25

4:34 pm-11:35 pm

1 stop6h 01m

$237

BuffaloKansas City

BUF - MCI

BUFMCI

Buffalo

Wed 8/27

8:50 am-5:40 pm

1 stop9h 50m

Kansas City

Wed 9/3

9:00 am-5:55 pm

2 stops7h 55m

$242

BuffaloSt. Louis

BUF - STL

BUFSTL

Buffalo

Wed 10/22

4:15 pm-10:05 pm

2 stops6h 50m

Lambert-St Louis

Sat 10/25

3:35 pm-10:50 pm

1 stop6h 15m

$242

BuffaloKansas City

BUF - MCI

BUFMCI

Buffalo

Fri 10/24

12:44 pm-3:28 pm

1 stop27h 44m

Kansas City

Sun 10/26

7:51 pm-1:14 pm

1 stop16h 23m

$248

BuffaloKansas City

BUF - MCI

BUFMCI

Buffalo

Wed 9/3

5:33 pm-10:10 pm

1 stop5h 37m

Kansas City

Mon 9/8

10:28 am-5:01 pm

1 stop5h 33m

$252

BuffaloSpringfield

BUF - SGF

BUFSGF

Buffalo

Fri 11/7

4:26 pm-9:09 pm

1 stop5h 43m

Springfield-Branson

Mon 11/10

3:19 pm-11:36 pm

1 stop7h 17m

$277

BuffaloKansas City

BUF - MCI

BUFMCI

Buffalo

Mon 10/27

8:04 am-4:05 pm

1 stop9h 01m

Kansas City

Tue 10/28

9:58 am-6:46 pm

2 stops7h 48m

$362

BuffaloSpringfield

BUF - SGF

BUFSGF

Buffalo

Mon 9/22

11:10 am-5:55 pm

2 stops7h 45m

Springfield-Branson

Sat 9/27

4:13 pm-11:37 pm

1 stop6h 24m

$374

Flights are sorted by cheapest round-trip flights first.

Deals found on 7/28

Showing 1-10 of 23 results
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Best time to book a flight from Buffalo to Missouri

Have a flexible travel schedule? Discover the best time to fly to Missouri from Buffalo with our price prediction graph.
Estimated round-trip price
Rates are based on past data. Find the cheapest month and day to book your flight based on your travel requirements, then search for cheap deals.

Cheapflights Insights

Everything you need to know about your flight from Buffalo to Missouri

What is the cheapest month to book a flight from Buffalo to Missouri?

Currently, August is the cheapest month in which you can book a flight from Buffalo to Missouri (average of $311). Flying from Buffalo to Missouri in March is currently the most expensive (average of $356). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.

What is the cheapest time of day to fly from BUF to MO?

Find hourly flight availability from Buffalo to Missouri. Discover flight options and departure times throughout the day, allowing you to choose a departure time that suits your schedule. Data last updated July 29, 2025.

When flying from Buffalo to Missouri, the time of day you decide to fly out makes little to no difference towards the overall price you’ll pay on tickets.

Reviews of airlines servicing Missouri

Get insights into the airlines that provide service to Missouri. Read reviews, discover amenities, and learn about the overall travel experience offered by airlines. Use this information to make informed decisions when choosing an airline for your flight to Missouri. Reviews last updated July 29, 2025.
Read through reviews of airlines operating flights from Buffalo to Missouri, such as Southwest, Delta, and United Airlines. You can also see how each airline stacks up in terms of entertainment options, comfort, food, crew/service, and boarding process.
Southwest
8.0
Very good
4,238 reviews

Comfort

8.0

Crew

8.6

Boarding

8.1

Entertainment

7.5

Food

7.0

Overall

8.0

Reviews

1 / 20
8.0
Excellent

Gina,Jul 2025

LAS - DEN

We experienced bad weather, which turned our 1.5 hour flight from Las Vegas to Denver, into 3.5. The pilot and crew kept us updated and explained that we had to circle and or possibly redirect to another airport. After circling for sometime, we were able to land smoothly in Denver. Thank you to all the flight crew, tower control, and all who got us to our destination safely.
Southwest
8.0
Very good
4,238 reviews
Southwest
8.0
Very good
4,238 reviews

Comfort

8.0

Crew

8.6

Boarding

8.1

Entertainment

7.5

Food

7.0

Overall

8.0

Reviews

1 / 20
8.0
Excellent

Gina,Jul 2025

LAS - DEN

We experienced bad weather, which turned our 1.5 hour flight from Las Vegas to Denver, into 3.5. The pilot and crew kept us updated and explained that we had to circle and or possibly redirect to another airport. After circling for sometime, we were able to land smoothly in Denver. Thank you to all the flight crew, tower control, and all who got us to our destination safely.
Delta
8.0
Very good
7,977 reviews
Southwest
8.0
Very good
4,238 reviews

Comfort

8.0

Crew

8.6

Boarding

8.1

Entertainment

7.5

Food

7.0

Overall

8.0

Reviews

1 / 20
8.0
Excellent

Gina,Jul 2025

LAS - DEN

We experienced bad weather, which turned our 1.5 hour flight from Las Vegas to Denver, into 3.5. The pilot and crew kept us updated and explained that we had to circle and or possibly redirect to another airport. After circling for sometime, we were able to land smoothly in Denver. Thank you to all the flight crew, tower control, and all who got us to our destination safely.
United Airlines
7.4
Good
8,899 reviews
Southwest
8.0
Very good
4,238 reviews

Comfort

8.0

Crew

8.6

Boarding

8.1

Entertainment

7.5

Food

7.0

Overall

8.0

Reviews

1 / 20
8.0
Excellent

Gina,Jul 2025

LAS - DEN

We experienced bad weather, which turned our 1.5 hour flight from Las Vegas to Denver, into 3.5. The pilot and crew kept us updated and explained that we had to circle and or possibly redirect to another airport. After circling for sometime, we were able to land smoothly in Denver. Thank you to all the flight crew, tower control, and all who got us to our destination safely.
American Airlines
7.2
Good
10,000 reviews
Southwest
8.0
Very good
4,238 reviews

Comfort

8.0

Crew

8.6

Boarding

8.1

Entertainment

7.5

Food

7.0

Overall

8.0

Reviews

1 / 20
8.0
Excellent

Gina,Jul 2025

LAS - DEN

We experienced bad weather, which turned our 1.5 hour flight from Las Vegas to Denver, into 3.5. The pilot and crew kept us updated and explained that we had to circle and or possibly redirect to another airport. After circling for sometime, we were able to land smoothly in Denver. Thank you to all the flight crew, tower control, and all who got us to our destination safely.
Frontier
5.9
Fair
3,238 reviews
Southwest
8.0
Very good
4,238 reviews

Comfort

8.0

Crew

8.6

Boarding

8.1

Entertainment

7.5

Food

7.0

Overall

8.0

Reviews

1 / 20
8.0
Excellent

Gina,Jul 2025

LAS - DEN

We experienced bad weather, which turned our 1.5 hour flight from Las Vegas to Denver, into 3.5. The pilot and crew kept us updated and explained that we had to circle and or possibly redirect to another airport. After circling for sometime, we were able to land smoothly in Denver. Thank you to all the flight crew, tower control, and all who got us to our destination safely.

Related info for your journey

Find useful and relevant information for your journey from Buffalo to Missouri. Access travel guides, tips, and recommendations to enhance your travel experience. Get information about local attractions, weather, transportation options, and more.

  • What airport do you fly from for flights from Buffalo to Missouri?

    Buffalo (BUF), located 8.3 mi from the city center, is the airport you fly out of when you book flights from Buffalo to Missouri.

  • What are the cheapest airlines to fly from Buffalo to Missouri one-way?

    To fly one-way, consider booking your trip with Frontier, which is currently one of the cheapest options available, starting at $117. Delta flights start at $119 while deals on American Airlines start at $119 one-way.

  • What are the most popular routes from Buffalo to Missouri?

    While some choose either Buffalo - Lambert-St Louis or Buffalo - Springfield-Branson, Buffalo - Kansas City is the most popular route from Buffalo to Missouri.

  • Can I find deals for flights from Buffalo to Missouri that include hotel bookings?

    Yes. In addition to deals on Buffalo to Missouri flights, Cheapflights offers vacation packages that include both flights and hotel.

  • How can I find direct flights from Buffalo to Missouri?

    After entering your origin and destination, apply the non-stop filter on the search result page to find direct flights from Buffalo to Missouri.

  • Can I find deals for business class flights from Buffalo to Missouri?

    Yes. Cheapflights offers flight deals from Buffalo to Missouri by cabin class. In addition to browsing deals, you can also filter by cabin class on the search results page after making a search.

  • What is the cheapest month to book a flight from Buffalo to Missouri?

    Currently, August is the cheapest month in which you can book a flight from Buffalo to Missouri (average of $311). Flying from Buffalo to Missouri in March is currently the most expensive (average of $356). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.

See more FAQs

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Alternative routes for Buffalo to Missouri

See prices for flight routes from nearby airports that may be better suited for you.
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Top 4 airlines flying from Buffalo to Missouri

Discover the top 4 airlines that operate flights from Buffalo to Missouri. Compare their services, reliability, and customer satisfaction ratings to choose the airline that best suits your travel preferences and needs. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated July 29, 2025.
AirlineCheapestAverageFlexibilityOn-time
SouthwestCheapest$236Average$412FlexibilityNo cancel feeOn-time63%
DeltaCheapest$246Average$357FlexibilityNo cancel feeOn-timeN/A
American AirlinesCheapest$248Average$368FlexibilityNo cancel feeOn-time71%
United AirlinesCheapest$293Average$626FlexibilityNo cancel feeOn-time69%

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