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$105+ Cheap flights from Buffalo (BUF) to Missouri

This is the cheapest one-way flight price found by a Cheapflights user in the last 72 hours by searching for a flight departing on 5/17. Fares are subject to change and may not be available on all flights or dates of travel.
BUF — STL
May 6 — May 131
Tue 5/6
Tue 5/13
1 adult, Economy
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Cheap flight deals from Buffalo to Missouri

Keep the following information in mind while searching for Buffalo to Missouri flight deals. Data was last updated May 1, 2025.

Most accurate provider

FlightHub
3 stars

Most trusted provider

eDreams
3 stars

Round-trip from

$224
(Gotogate)

One-way from

$105
(Frontier)

Popular in

January

Cheapest in

February

Average price

$404
Provider with most accurate pricing for Buffalo-Kansas City flight deals.
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Provider most trusted by Cheapflights users for Buffalo-Kansas City flights.
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From Buffalo to Missouri
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One-way flight from Buffalo to Missouri
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Highest demand for flights based on searches. 16% potential increase in price ($90 potential increase over avg. RT price).
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Cheapest flight prices on average. 9% potential price decrease ($40 potential savings vs. average RT price).
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Average for round-trip flights in May 2025
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Find flight deals from Buffalo to Missouri

Cheapest flights from Buffalo to Missouri
Explore the most affordable flight options available from Buffalo to Missouri. Find the lowest fares from popular airlines and budget airlines, with prices last updated on May 1, 2025.

This Frontier deal was found by Cheapflights users on 4/30. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Frontier is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 5/311:38 amBUF - STL
1 stop13h 28mFrontier
Sat 5/105:45 pmSTL - BUF
1 stop14h 16mFrontier
Deal found 4/30$189
This Delta deal was found by Cheapflights users on 4/30. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 7/412:10 pmBUF - STL
1 stop7h 34mDelta
Sat 7/126:04 pmSTL - BUF
1 stop3h 19mDelta
Deal found 4/30$244
This American Airlines deal was found by Cheapflights users on 4/30. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 7/46:00 amBUF - STL
2 stops6h 59mAmerican Airlines
Sat 7/125:14 pmSTL - BUF
1 stop4h 43mAmerican Airlines
Deal found 4/30$249
This American Airlines deal was found by Cheapflights users on 4/28. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 5/285:30 amBUF - MCI
1 stop6h 15mAmerican Airlines
Wed 6/43:51 pmMCI - BUF
1 stop7h 23mAmerican Airlines
Deal found 4/28$271
This Southwest deal was found by Cheapflights users on 4/30. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 6/27:30 pmBUF - STL
1 stop3h 30mSouthwest
Fri 6/64:35 pmSTL - BUF
2 stops6h 10mSouthwest
Deal found 4/30$274
This Southwest deal was found by Cheapflights users on 4/28. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 5/287:20 pmBUF - MCI
1 stop3h 50mSouthwest
Wed 6/42:55 pmMCI - BUF
2 stops6h 40mSouthwest
Deal found 4/28$276
This American Airlines deal was found by Cheapflights users on 4/30. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 5/246:49 amBUF - SGF
1 stop5h 49mAmerican Airlines
Tue 5/276:39 pmSGF - BUF
1 stop4h 35mAmerican Airlines
Deal found 4/30$304
This United Airlines deal was found by Cheapflights users on 4/30. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 6/137:00 amBUF - STL
1 stop4h 45mUnited Airlines
Mon 6/166:30 amSTL - BUF
2 stops6h 39mUnited Airlines
Deal found 4/30$304
This Delta deal was found by Cheapflights users on 4/28. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 6/286:30 amBUF - MCI
1 stop4h 14mDelta
Mon 6/305:44 pmMCI - BUF
1 stop4h 46mDelta
Deal found 4/28$324
This United Airlines deal was found by Cheapflights users on 4/29. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 5/286:15 amBUF - MCI
2 stops9h 10mUnited Airlines
Mon 6/23:21 pmMCI - BUF
1 stop4h 40mUnited Airlines
Deal found 4/29$336
This United Airlines deal was found by Cheapflights users on 4/30. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 5/86:45 amBUF - SGF
1 stop5h 08mUnited Airlines
Tue 5/139:10 amSGF - BUF
2 stops11h 12mUnited Airlines
Deal found 4/30$413
This American Airlines deal was found by Cheapflights users on 4/30. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 7/48:00 amBUF - COU
1 stop4h 10mAmerican Airlines
Sat 7/126:22 amCOU - BUF
2 stops10h 47mAmerican Airlines
Deal found 4/30$423

Cheapflights Fare Finder

Customize your flight search to find flights from Buffalo to Missouri that fit within your specific budget. Explore options based on user searches and filter the results based on your desired price range. Find flights that match your budget for a cost-effective journey. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated May 1, 2025.
Use the filters below to find and compare flights from Buffalo to Missouri that are best for you.

Fly from

Buffalo

Fly to

Missouri

Route

Depart

Return

Price

BuffaloSt. Louis

BUF - STL

BUFSTL

Buffalo

Fri 5/16

9:51 am-12:14 am

1 stop15h 23m

Lambert-St Louis

Sun 5/18

5:45 pm-9:01 am

1 stop14h 16m

$224

BuffaloSt. Louis

BUF - STL

BUFSTL

Buffalo

Fri 7/4

12:10 pm-6:44 pm

1 stop7h 34m

Lambert-St Louis

Sat 7/12

6:04 pm-10:23 pm

1 stop3h 19m

$244

BuffaloSt. Louis

BUF - STL

BUFSTL

Buffalo

Fri 7/4

6:00 am-11:59 am

2 stops6h 59m

Lambert-St Louis

Sat 7/12

5:14 pm-10:57 pm

1 stop4h 43m

$249

BuffaloKansas City

BUF - MCI

BUFMCI

Buffalo

Wed 5/28

5:30 am-10:45 am

1 stop6h 15m

Kansas City

Wed 6/4

3:51 pm-12:14 am

1 stop7h 23m

$271

BuffaloSt. Louis

BUF - STL

BUFSTL

Buffalo

Mon 6/2

7:30 pm-10:00 pm

1 stop3h 30m

Lambert-St Louis

Fri 6/6

4:35 pm-11:45 pm

2 stops6h 10m

$274

BuffaloKansas City

BUF - MCI

BUFMCI

Buffalo

Wed 5/28

7:20 pm-10:10 pm

1 stop3h 50m

Kansas City

Wed 6/4

2:55 pm-10:35 pm

2 stops6h 40m

$276

BuffaloSt. Louis

BUF - STL

BUFSTL

Buffalo

Fri 6/13

7:00 am-10:45 am

1 stop4h 45m

Lambert-St Louis

Mon 6/16

6:30 am-2:09 pm

2 stops6h 39m

$304

BuffaloSpringfield

BUF - SGF

BUFSGF

Buffalo

Sat 5/24

6:49 am-11:38 am

1 stop5h 49m

Springfield-Branson

Tue 5/27

6:39 pm-12:14 am

1 stop4h 35m

$304

BuffaloKansas City

BUF - MCI

BUFMCI

Buffalo

Sat 6/28

6:30 am-9:44 am

1 stop4h 14m

Kansas City

Mon 6/30

5:44 pm-11:30 pm

1 stop4h 46m

$324

BuffaloKansas City

BUF - MCI

BUFMCI

Buffalo

Wed 5/28

6:15 am-2:25 pm

2 stops9h 10m

Kansas City

Mon 6/2

3:21 pm-9:01 pm

1 stop4h 40m

$336

Flights are sorted by cheapest round-trip flights first.

Deals found on 4/30

Showing 1-10 of 24 results
1
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Best time to book a flight from Buffalo to Missouri

Have a flexible travel schedule? Discover the best time to fly to Missouri from Buffalo with our price prediction graph.
Estimated round-trip price
Rates are based on past data. Find the cheapest month and day to book your flight based on your travel requirements, then search for cheap deals.

Cheapflights Insights

Everything you need to know about your flight from Buffalo to Missouri

What is the cheapest month to book a flight from Buffalo to Missouri?

Currently, August is the cheapest month in which you can book a flight from Buffalo to Missouri (average of $311). Flying from Buffalo to Missouri in March is currently the most expensive (average of $356). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.

What is the cheapest time of day to fly from BUF to MO?

Find hourly flight availability from Buffalo to Missouri. Discover flight options and departure times throughout the day, allowing you to choose a departure time that suits your schedule. Data last updated May 1, 2025.

When flying from Buffalo to Missouri, the time of day you decide to fly out makes little to no difference towards the overall price you’ll pay on tickets.

Rainfall in Missouri by month

Plan your trip to Missouri by taking into account the average rainfall totals by month.

In terms of precipitation, rainfall in Missouri ranges from 1.1 - 5.2 inches per month. May is typically the wettest month, when rainfall can reach 5.2 in. January is typically the driest time to visit Missouri when rainfall is around 1.1 in.

Temperature in Missouri by month

Plan your trip to Missouri by taking into account the average temperature totals by month.

If weather is an important factor for your trip to Missouri, use this chart to help with planning. For those seeking warmer temperatures, July is the ideal time of year to visit, when temperatures reach an average of 78.8 F. Travelers looking to avoid the cold should look outside of January, when temperatures are typically at their lowest (around 28.4 F).

Reviews of airlines servicing Missouri

Get insights into the airlines that provide service to Missouri. Read reviews, discover amenities, and learn about the overall travel experience offered by airlines. Use this information to make informed decisions when choosing an airline for your flight to Missouri. Reviews last updated May 1, 2025.
Read reviews from past customers who have flown Southwest, Delta and United Airlines from Buffalo to Missouri. Reviews also offer insight into each airline's entertainment options, comfort, food, crew/service, and boarding process.
Southwest
8.0
Very good
4,294 reviews

Comfort

8.0

Boarding

8.2

Entertainment

7.6

Food

7.1

Crew

8.6

Overall

8.0

Reviews

1 / 20
10.0
Excellent

Gina,Apr 2025

LAS - DEN

Good, the crew was friendly and helpful. The pilot had great skills in keeping the plane stable through rough turbulence. Smooth landing, too! Thank you!
Southwest
8.0
Very good
4,294 reviews
Southwest
8.0
Very good
4,294 reviews

Comfort

8.0

Boarding

8.2

Entertainment

7.6

Food

7.1

Crew

8.6

Overall

8.0

Reviews

1 / 20
10.0
Excellent

Gina,Apr 2025

LAS - DEN

Good, the crew was friendly and helpful. The pilot had great skills in keeping the plane stable through rough turbulence. Smooth landing, too! Thank you!
Delta
8.0
Very good
7,934 reviews
Southwest
8.0
Very good
4,294 reviews

Comfort

8.0

Boarding

8.2

Entertainment

7.6

Food

7.1

Crew

8.6

Overall

8.0

Reviews

1 / 20
10.0
Excellent

Gina,Apr 2025

LAS - DEN

Good, the crew was friendly and helpful. The pilot had great skills in keeping the plane stable through rough turbulence. Smooth landing, too! Thank you!
United Airlines
7.4
Good
8,696 reviews
Southwest
8.0
Very good
4,294 reviews

Comfort

8.0

Boarding

8.2

Entertainment

7.6

Food

7.1

Crew

8.6

Overall

8.0

Reviews

1 / 20
10.0
Excellent

Gina,Apr 2025

LAS - DEN

Good, the crew was friendly and helpful. The pilot had great skills in keeping the plane stable through rough turbulence. Smooth landing, too! Thank you!
American Airlines
7.2
Good
10,000 reviews
Southwest
8.0
Very good
4,294 reviews

Comfort

8.0

Boarding

8.2

Entertainment

7.6

Food

7.1

Crew

8.6

Overall

8.0

Reviews

1 / 20
10.0
Excellent

Gina,Apr 2025

LAS - DEN

Good, the crew was friendly and helpful. The pilot had great skills in keeping the plane stable through rough turbulence. Smooth landing, too! Thank you!
Frontier
6.0
Okay
3,287 reviews
Southwest
8.0
Very good
4,294 reviews

Comfort

8.0

Boarding

8.2

Entertainment

7.6

Food

7.1

Crew

8.6

Overall

8.0

Reviews

1 / 20
10.0
Excellent

Gina,Apr 2025

LAS - DEN

Good, the crew was friendly and helpful. The pilot had great skills in keeping the plane stable through rough turbulence. Smooth landing, too! Thank you!

Related info for your journey

Find useful and relevant information for your journey from Buffalo to Missouri. Access travel guides, tips, and recommendations to enhance your travel experience. Get information about local attractions, weather, transportation options, and more.

  • What airport do you fly from for flights from Buffalo to Missouri?

    Buffalo (BUF), located 8.3 mi from the city center, is the airport you fly out of when you book flights from Buffalo to Missouri.

  • What are the cheapest airlines to fly from Buffalo to Missouri one-way?

    To fly one-way, consider booking your trip with Frontier, which is currently one of the cheapest options available, starting at $105. American Airlines flights start at $126 while deals on Delta start at $126 one-way.

  • What are the most popular routes from Buffalo to Missouri?

    While some choose either Buffalo - Lambert-St Louis or Buffalo - Springfield-Branson, Buffalo - Kansas City is the most popular route from Buffalo to Missouri.

  • Can I find deals for flights from Buffalo to Missouri that include hotel bookings?

    Yes. In addition to deals on Buffalo to Missouri flights, Cheapflights offers vacation packages that include both flights and hotel.

  • How can I find direct flights from Buffalo to Missouri?

    After entering your origin and destination, apply the non-stop filter on the search result page to find direct flights from Buffalo to Missouri.

  • Can I find deals for business class flights from Buffalo to Missouri?

    Yes. Cheapflights offers flight deals from Buffalo to Missouri by cabin class. In addition to browsing deals, you can also filter by cabin class on the search results page after making a search.

  • What is the cheapest month to book a flight from Buffalo to Missouri?

    Currently, August is the cheapest month in which you can book a flight from Buffalo to Missouri (average of $311). Flying from Buffalo to Missouri in March is currently the most expensive (average of $356). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.

See more FAQs

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See prices for flight routes from nearby airports that may be better suited for you.
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Top 4 airlines flying from Buffalo to Missouri

Discover the top 4 airlines that operate flights from Buffalo to Missouri. Compare their services, reliability, and customer satisfaction ratings to choose the airline that best suits your travel preferences and needs. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated May 1, 2025.
AirlineCheapestAverageFlexibilityOn-time
American AirlinesCheapest$168Average$378FlexibilityNo cancel feeOn-time71%
DeltaCheapest$237Average$395FlexibilityNo cancel feeOn-timeN/A
United AirlinesCheapest$256Average$525FlexibilityNo cancel feeOn-time69%
SouthwestCheapest$301Average$444FlexibilityNo cancel feeOn-time63%

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