Missouri

$98+ Cheap flights from Buffalo (BUF) to Missouri

This is the cheapest one-way flight price found by a Cheapflights user in the last 72 hours by searching for a flight departing on 4/15. Fares are subject to change and may not be available on all flights or dates of travel.
BUF — STL
Apr 14 — Apr 211
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Cheap flight deals from Buffalo to Missouri

Cheapest flights from Buffalo to Missouri
Explore the most affordable flight options available from Buffalo to Missouri. Find the lowest fares from popular airlines and budget airlines, with prices last updated on March 15, 2026.

This Mytrip deal was found by Cheapflights users on 3/13. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Mytrip is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 4/109:05 pm
BUF
-
STL
1 stop11h 46m
Frontier
Fri 4/174:59 pm
STL
-
BUF
1 stop16h 50m
Frontier
Deal found 3/13$244
This Southwest deal was found by Cheapflights users on 3/13. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 5/46:15 am
BUF
-
STL
1 stop8h 30m
Southwest
Wed 5/135:35 am
STL
-
BUF
1 stop3h 45m
Southwest
Deal found 3/13$289
This Frontier deal was found by Cheapflights users on 3/13. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Frontier is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 4/2011:19 am
BUF
-
STL
1 stop13h 00m
Frontier
Thu 4/234:59 pm
STL
-
BUF
1 stop16h 08m
Frontier
Deal found 3/13$290
This American Airlines deal was found by Cheapflights users on 3/15. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 5/13:01 pm
BUF
-
COU
1 stop7h 29m
American Airlines
Mon 5/44:28 pm
COU
-
BUF
1 stop4h 08m
American Airlines
Deal found 3/15$298
This American Airlines deal was found by Cheapflights users on 3/11. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 5/207:25 am
BUF
-
COU
2 stops9h 33m
American Airlines
Sat 5/236:43 pm
COU
-
BUF
1 stop4h 31m
American Airlines
Deal found 3/11$304
This Southwest deal was found by Cheapflights users on 3/13. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 4/204:00 pm
BUF
-
STL
2 stops8h 15m
Southwest
Thu 4/235:40 am
STL
-
BUF
1 stop3h 35m
Southwest
Deal found 3/13$306
This American Airlines deal was found by Cheapflights users on 3/14. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 4/116:00 am
BUF
-
STL
1 stop6h 47m
American Airlines
Sat 4/188:00 am
STL
-
BUF
1 stop5h 21m
American Airlines
Deal found 3/14$307
This American Airlines deal was found by Cheapflights users on 3/14. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 6/246:00 am
BUF
-
SGF
1 stop5h 00m
American Airlines
Mon 6/292:21 pm
SGF
-
BUF
1 stop6h 36m
American Airlines
Deal found 3/14$309
This Kiwi.com deal was found by Cheapflights users on 3/15. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 5/1411:36 am
BUF
-
STL
1 stop6h 18m
Frontier
Mon 5/185:27 pm
STL
-
BUF
1 stop16h 14m
Frontier
Deal found 3/15$309
This Southwest deal was found by Cheapflights users on 3/14. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 4/113:40 pm
BUF
-
STL
1 stop4h 30m
Southwest
Sat 4/186:10 am
STL
-
BUF
2 stops9h 25m
Southwest
Deal found 3/14$314
This Southwest deal was found by Cheapflights users on 3/12. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 4/216:55 pm
BUF
-
MCI
1 stop4h 35m
Southwest
Tue 4/285:25 am
MCI
-
BUF
1 stop3h 55m
Southwest
Deal found 3/12$319
This American Airlines deal was found by Cheapflights users on 3/13. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 4/173:01 pm
BUF
-
SGF
1 stop7h 04m
American Airlines
Sun 4/195:19 am
SGF
-
BUF
1 stop4h 32m
American Airlines
Deal found 3/13$322

Find flight deals from Buffalo to Missouri

Keep the following information in mind while searching for Buffalo to Missouri flight deals. Data was last updated March 15, 2026.

Most accurate provider

FlightHub
3 stars

Most trusted provider

FlightHub
3 stars

Round-trip from

$244
(Mytrip)

One-way from

$98
(Kiwi.com)

Popular in

March

Cheapest in

September

Average price

$575
Provider with most accurate pricing for Buffalo-Lambert-St Louis flight deals.
Provider most trusted by Cheapflights users for Buffalo-Lambert-St Louis flights.
From Buffalo to Missouri
One-way flight from Buffalo to Missouri
Highest demand for flights based on searches. 21% potential increase in price ($102 potential increase over avg. RT price).
Cheapest flight prices on average. 5% potential price decrease ($19 potential savings vs. average RT price).
Average for round-trip flights in March 2026

Cheapflights Fare Finder

 
Customize your flight search to find flights from Buffalo to Missouri that fit within your specific budget. Explore options based on user searches and filter the results based on your desired price range. Find flights that match your budget for a cost-effective journey. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated March 15, 2026.
Use the filters below to find and compare flights from Buffalo to Missouri that are best for you.

Fly from

Fly to

Route

Depart

Return

Price

Cheapest round-trip

BuffaloColumbia

BUF - COU

BUFCOU

Buffalo

Fri 5/1

6:00 am-9:46 am

1 stop4h 46m

Columbia Regional

Mon 5/4

6:00 am-2:21 pm

1 stop7h 21m

$298

BuffaloColumbia

BUF - COU

BUFCOU

Buffalo

Wed 5/20

7:25 am-3:58 pm

2 stops9h 33m

Columbia Regional

Sat 5/23

6:43 pm-12:14 am

1 stop4h 31m

$304

BuffaloSt. Louis

BUF - STL

BUFSTL

Buffalo

Sat 4/11

6:00 am-11:47 am

1 stop6h 47m

Lambert-St Louis

Sat 4/18

8:00 am-2:21 pm

1 stop5h 21m

$307

BuffaloSt. Louis

BUF - STL

BUFSTL

Buffalo

Sat 4/11

3:40 pm-7:10 pm

1 stop4h 30m

Lambert-St Louis

Sat 4/18

6:10 am-4:35 pm

2 stops9h 25m

$314

BuffaloSpringfield

BUF - SGF

BUFSGF

Buffalo

Fri 4/17

3:01 pm-9:05 pm

1 stop7h 04m

Springfield-Branson

Sun 4/19

5:19 am-10:51 am

1 stop4h 32m

$322

BuffaloSt. Louis

BUF - STL

BUFSTL

Buffalo

Thu 4/30

7:00 am-11:09 am

1 stop5h 09m

Lambert-St Louis

Sun 5/3

7:05 am-2:21 pm

1 stop6h 16m

$344
Quickest round-trip

BuffaloKansas City

BUF - MCI

BUFMCI

Buffalo

Wed 5/13

6:55 pm-10:30 pm

1 stop4h 35m

Kansas City

Sun 5/17

5:25 am-10:25 am

1 stop4h 00m

$353

BuffaloSt. Louis

BUF - STL

BUFSTL

Buffalo

Mon 5/4

5:55 pm-9:13 pm

1 stop4h 18m

Lambert-St Louis

Tue 5/5

9:21 am-4:54 pm

1 stop6h 33m

$359

BuffaloSt. Louis

BUF - STL

BUFSTL

Buffalo

Fri 6/5

11:55 am-11:57 pm

1 stop13h 02m

Lambert-St Louis

Sun 6/7

4:44 pm-12:16 pm

1 stop18h 32m

$362

BuffaloKansas City

BUF - MCI

BUFMCI

Buffalo

Fri 4/17

6:02 pm-9:59 pm

1 stop4h 57m

Kansas City

Tue 4/28

8:00 am-6:49 pm

2 stops9h 49m

$368

Flights are sorted by cheapest round-trip flights first.

Deals found on 3/14

Showing 1-10 of 51 resultsSorted by cheapest first
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Best time to book a flight from Buffalo to Missouri

Have a flexible travel schedule? Discover the best time to fly to Missouri from Buffalo with our price prediction graph.
Estimated round-trip price
Rates are based on past data. Find the cheapest month and day to book your flight based on your travel requirements, then search for cheap deals.

Cheapflights Insights

Everything you need to know about your flight from Buffalo to Missouri

What is the cheapest month to book a flight from Buffalo to Missouri?

Currently, August is the cheapest month in which you can book a flight from Buffalo to Missouri (average of $112). Flying from Buffalo to Missouri in February is currently the most expensive (average of $277). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.

Reviews of airlines servicing Missouri

Get insights into the airlines that provide service to Missouri. Read reviews, discover amenities, and learn about the overall travel experience offered by airlines. Use this information to make informed decisions when choosing an airline for your flight to Missouri. Reviews last updated March 15, 2026.
Read through reviews of airlines operating flights from Buffalo to Missouri, such as Southwest,Delta, andUnited Airlines. You can also see how each airline stacks up in terms of entertainment options, comfort, food, crew/service, and boarding process.

Food

7.0

Crew

8.6

Entertainment

7.5

Comfort

8.0

Overall

8.0

Boarding

8.1

Reviews

1 / 20
10.0
Excellent

Anonymous,Mar 2026

KOA - HNL

pretty smooth and fast service ever, that flight is very helpful each and everyone for price and also fright for free..

Food

7.0

Crew

8.6

Entertainment

7.5

Comfort

8.0

Overall

8.0

Boarding

8.1

Reviews

1 / 20
10.0
Excellent

Anonymous,Mar 2026

KOA - HNL

pretty smooth and fast service ever, that flight is very helpful each and everyone for price and also fright for free..

Food

7.0

Crew

8.6

Entertainment

7.5

Comfort

8.0

Overall

8.0

Boarding

8.1

Reviews

1 / 20
10.0
Excellent

Anonymous,Mar 2026

KOA - HNL

pretty smooth and fast service ever, that flight is very helpful each and everyone for price and also fright for free..

Food

7.0

Crew

8.6

Entertainment

7.5

Comfort

8.0

Overall

8.0

Boarding

8.1

Reviews

1 / 20
10.0
Excellent

Anonymous,Mar 2026

KOA - HNL

pretty smooth and fast service ever, that flight is very helpful each and everyone for price and also fright for free..

Food

7.0

Crew

8.6

Entertainment

7.5

Comfort

8.0

Overall

8.0

Boarding

8.1

Reviews

1 / 20
10.0
Excellent

Anonymous,Mar 2026

KOA - HNL

pretty smooth and fast service ever, that flight is very helpful each and everyone for price and also fright for free..

Related info for your journey

Find useful and relevant information for your journey from Buffalo to Missouri. Access travel guides, tips, and recommendations to enhance your travel experience. Get information about local attractions, weather, transportation options, and more.
  • What airport do you fly from for flights from Buffalo to Missouri?

    Buffalo (BUF), located 8.3 mi from the city center, is the airport you fly out of when you book flights from Buffalo to Missouri.

  • How long is the flight from Buffalo to Missouri?

    A quick flight from Buffalo to Missouri can take about 4h 46m. Frontier provides one of the quickest options available for as low as $298. Buffalo and Missouri are separated by a distance of 758 mi. This flight may include one or multiple stops.

  • What are the cheapest airlines to fly from Buffalo to Missouri one-way?

    To fly one-way, consider booking your trip with American Airlines, which is currently one of the cheapest options available, starting at $95. United Airlines flights start at $99 while deals on Delta start at $118 one-way.

  • What are the most popular routes from Buffalo to Missouri?

  • Can I find deals for flights from Buffalo to Missouri that include hotel bookings?

    Yes. In addition to deals on Buffalo to Missouri flights, Cheapflights offers vacation packages that include both flights and hotel.

  • How can I find direct flights from Buffalo to Missouri?

    After entering your origin and destination, apply the non-stop filter on the search result page to find direct flights from Buffalo to Missouri.

  • Can I find deals for business class flights from Buffalo to Missouri?

    Yes. Cheapflights offers flight deals from Buffalo to Missouri by cabin class. In addition to browsing deals, you can also filter by cabin class on the search results page after making a search.

  • What is the cheapest month to book a flight from Buffalo to Missouri?

    Currently, August is the cheapest month in which you can book a flight from Buffalo to Missouri (average of $112). Flying from Buffalo to Missouri in February is currently the most expensive (average of $277). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.

See more FAQs

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Alternative routes for Buffalo to Missouri

See prices for flight routes from nearby airports that may be better suited for you.

Top 4 airlines flying from Buffalo to Missouri

Discover the top 4 airlines that operate flights from Buffalo to Missouri. Compare their services, reliability, and customer satisfaction ratings to choose the airline that best suits your travel preferences and needs. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated March 15, 2026.
AirlineCheapestAverageFlexibilityOn-time
DeltaCheapest$164Average$356FlexibilityNo cancel feeOn-timeN/A
American AirlinesCheapest$197Average$373FlexibilityNo cancel feeOn-time71%
SouthwestCheapest$236Average$422FlexibilityNo cancel feeOn-time63%
United AirlinesCheapest$294Average$392FlexibilityNo cancel feeOn-time69%

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