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$77+ Cheap flights from Buffalo (BUF) to Missouri

This is the cheapest one-way flight price found by a Cheapflights user in the last 72 hours by searching for a flight departing on 11/18. Fares are subject to change and may not be available on all flights or dates of travel.
BUF — STL
Oct 11 — Oct 181
Sat 10/11
Sat 10/18
1 adult, Economy
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Cheap flight deals from Buffalo to Missouri

Keep the following information in mind while searching for Buffalo to Missouri flight deals. Data was last updated September 11, 2025.

Round-trip from

$206
(Southwest)

One-way from

$77
(Southwest)

Popular in

January

Cheapest in

September

Average price

$291
From Buffalo to Missouri
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One-way flight from Buffalo to Missouri
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Highest demand for flights based on searches. 20% potential increase in price ($108 potential increase over avg. RT price).
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Cheapest flight prices on average. 10% potential price decrease ($42 potential savings vs. average RT price).
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Average for round-trip flights in September 2025
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Find flight deals from Buffalo to Missouri

Cheapest flights from Buffalo to Missouri
Explore the most affordable flight options available from Buffalo to Missouri. Find the lowest fares from popular airlines and budget airlines, with prices last updated on September 11, 2025.

This Southwest deal was found by Cheapflights users on 9/9. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 10/15:50 amBUF - MCI
1 stop7h 05mSouthwest
Wed 10/82:30 pmMCI - BUF
2 stops6h 45mSouthwest
Deal found 9/9$206
This Southwest deal was found by Cheapflights users on 9/10. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 10/42:30 pmBUF - MCI
1 stop6h 40mSouthwest
Tue 10/710:00 amMCI - BUF
1 stop5h 25mSouthwest
Deal found 9/10$207
This American Airlines deal was found by Cheapflights users on 9/11. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 10/412:10 pmBUF - MCI
1 stop6h 30mAmerican Airlines
Tue 10/76:00 amMCI - BUF
1 stop9h 57mAmerican Airlines
Deal found 9/11$213
This American Airlines deal was found by Cheapflights users on 9/10. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 11/87:40 amBUF - MCI
1 stop8h 37mAmerican Airlines
Mon 11/175:53 amMCI - BUF
1 stop5h 24mAmerican Airlines
Deal found 9/10$222
This American Airlines deal was found by Cheapflights users on 9/11. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 10/236:00 amBUF - STL
1 stop4h 56mAmerican Airlines
Mon 10/274:34 pmSTL - BUF
1 stop6h 01mAmerican Airlines
Deal found 9/11$224
This Southwest deal was found by Cheapflights users on 9/9. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 10/274:15 pmBUF - MCI
1 stop7h 45mSouthwest
Tue 10/286:20 amMCI - BUF
1 stop8h 00mSouthwest
Deal found 9/9$235
This American Airlines deal was found by Cheapflights users on 9/9. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 10/306:42 pmBUF - MCI
1 stop5h 31mAmerican Airlines
Thu 11/135:53 amMCI - BUF
1 stop5h 12mAmerican Airlines
Deal found 9/9$237
This Delta deal was found by Cheapflights users on 9/10. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 11/25:20 amBUF - STL
1 stop4h 17mDelta
Wed 11/55:15 pmSTL - BUF
1 stop5h 24mDelta
Deal found 9/10$246
This American Airlines deal was found by Cheapflights users on 9/10. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 11/167:40 amBUF - STL
1 stop9h 32mAmerican Airlines
Thu 11/205:00 amSTL - BUF
1 stop5h 02mAmerican Airlines
Deal found 9/10$248
This Frontier deal was found by Cheapflights users on 9/9. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Frontier is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 10/309:04 pmBUF - MCI
2 stops14h 13mFrontier
Sun 11/28:28 pmMCI - BUF
2 stops16h 09mFrontier
Deal found 9/9$251
This American Airlines deal was found by Cheapflights users on 9/11. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 9/306:00 amBUF - STL
1 stop7h 23mAmerican Airlines
Fri 10/36:10 amSTL - BUF
1 stop3h 56mAmerican Airlines
Deal found 9/11$251
This United Airlines deal was found by Cheapflights users on 9/10. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 10/267:00 amBUF - MCI
1 stop4h 40mUnited Airlines
Tue 10/286:00 amMCI - BUF
1 stop6h 17mUnited Airlines
Deal found 9/10$253

Cheapflights Fare Finder

 
Customize your flight search to find flights from Buffalo to Missouri that fit within your specific budget. Explore options based on user searches and filter the results based on your desired price range. Find flights that match your budget for a cost-effective journey. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated September 11, 2025.
Use the filters below to find and compare flights from Buffalo to Missouri that are best for you.

Fly from

Buffalo

Fly to

Missouri

Route

Depart

Return

Price

BuffaloKansas City

BUF - MCI

BUFMCI

Buffalo

Sat 10/4

11:46 am-6:34 pm

2 stops7h 48m

Kansas City

Tue 10/7

6:00 am-4:57 pm

1 stop9h 57m

$218

BuffaloKansas City

BUF - MCI

BUFMCI

Buffalo

Sat 11/8

7:40 am-3:17 pm

1 stop8h 37m

Kansas City

Mon 11/17

5:53 am-12:17 pm

1 stop5h 24m

$222

BuffaloKansas City

BUF - MCI

BUFMCI

Buffalo

Sat 10/4

4:00 pm-9:30 pm

1 stop6h 30m

Kansas City

Tue 10/7

10:40 am-8:30 pm

2 stops8h 50m

$225

BuffaloSt. Louis

BUF - STL

BUFSTL

Buffalo

Sun 11/2

5:20 am-8:37 am

1 stop4h 17m

Lambert-St Louis

Wed 11/5

5:15 pm-11:39 pm

1 stop5h 24m

$246

BuffaloSt. Louis

BUF - STL

BUFSTL

Buffalo

Sun 11/16

7:40 am-4:12 pm

1 stop9h 32m

Lambert-St Louis

Thu 11/20

5:00 am-11:02 am

1 stop5h 02m

$248

BuffaloKansas City

BUF - MCI

BUFMCI

Buffalo

Fri 12/12

5:24 pm-10:54 pm

1 stop6h 30m

Kansas City

Mon 12/15

6:00 am-2:20 pm

1 stop7h 20m

$249

BuffaloSt. Louis

BUF - STL

BUFSTL

Buffalo

Thu 2/26

6:50 pm-11:40 pm

1 stop5h 50m

Lambert-St Louis

Sun 3/1

6:45 am-11:51 am

1 stop4h 06m

$250

BuffaloKansas City

BUF - MCI

BUFMCI

Buffalo

Thu 10/30

9:04 pm-10:17 am

2 stops14h 13m

Kansas City

Sun 11/2

8:28 pm-1:37 pm

2 stops16h 09m

$251

BuffaloSt. Louis

BUF - STL

BUFSTL

Buffalo

Tue 9/30

6:00 am-12:23 pm

1 stop7h 23m

Lambert-St Louis

Fri 10/3

6:10 am-11:06 am

1 stop3h 56m

$251

BuffaloSt. Louis

BUF - STL

BUFSTL

Buffalo

Tue 9/30

6:00 am-12:23 pm

1 stop7h 23m

Lambert-St Louis

Wed 10/1

2:11 pm-9:43 pm

1 stop6h 32m

$253

Flights are sorted by cheapest round-trip flights first.

Deals found on 9/10

Showing 1-10 of 50 results
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Best time to book a flight from Buffalo to Missouri

Have a flexible travel schedule? Discover the best time to fly to Missouri from Buffalo with our price prediction graph.
Estimated round-trip price
Rates are based on past data. Find the cheapest month and day to book your flight based on your travel requirements, then search for cheap deals.

Cheapflights Insights

Everything you need to know about your flight from Buffalo to Missouri

What is the cheapest month to book a flight from Buffalo to Missouri?

Currently, August is the cheapest month in which you can book a flight from Buffalo to Missouri (average of $311). Flying from Buffalo to Missouri in March is currently the most expensive (average of $356). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.

What is the cheapest time of day to fly from BUF to MO?

Find hourly flight availability from Buffalo to Missouri. Discover flight options and departure times throughout the day, allowing you to choose a departure time that suits your schedule. Data last updated September 11, 2025.

When flying from Buffalo to Missouri, the time of day you decide to fly out makes little to no difference towards the overall price you’ll pay on tickets.

Reviews of airlines servicing Missouri

Get insights into the airlines that provide service to Missouri. Read reviews, discover amenities, and learn about the overall travel experience offered by airlines. Use this information to make informed decisions when choosing an airline for your flight to Missouri. Reviews last updated September 11, 2025.
Read through reviews of airlines operating flights from Buffalo to Missouri, such as Southwest, Delta, and United Airlines. You can also see how each airline stacks up in terms of entertainment options, comfort, food, crew/service, and boarding process.
Southwest
8.0
Very good
4,248 reviews

Entertainment

7.5

Crew

8.6

Boarding

8.1

Comfort

8.0

Overall

8.0

Food

7.0

Reviews

1 / 20
2.0
Mediocre

Mike,Aug 2025

OKC - AUS

AC was not adequate, even on a night flight. WiFi subpar even for the airlines
Southwest
8.0
Very good
4,248 reviews
Southwest
8.0
Very good
4,248 reviews

Entertainment

7.5

Crew

8.6

Boarding

8.1

Comfort

8.0

Overall

8.0

Food

7.0

Reviews

1 / 20
2.0
Mediocre

Mike,Aug 2025

OKC - AUS

AC was not adequate, even on a night flight. WiFi subpar even for the airlines
Delta
8.0
Very good
7,960 reviews
Southwest
8.0
Very good
4,248 reviews

Entertainment

7.5

Crew

8.6

Boarding

8.1

Comfort

8.0

Overall

8.0

Food

7.0

Reviews

1 / 20
2.0
Mediocre

Mike,Aug 2025

OKC - AUS

AC was not adequate, even on a night flight. WiFi subpar even for the airlines
United Airlines
7.4
Good
8,937 reviews
Southwest
8.0
Very good
4,248 reviews

Entertainment

7.5

Crew

8.6

Boarding

8.1

Comfort

8.0

Overall

8.0

Food

7.0

Reviews

1 / 20
2.0
Mediocre

Mike,Aug 2025

OKC - AUS

AC was not adequate, even on a night flight. WiFi subpar even for the airlines
American Airlines
7.2
Good
10,000 reviews
Southwest
8.0
Very good
4,248 reviews

Entertainment

7.5

Crew

8.6

Boarding

8.1

Comfort

8.0

Overall

8.0

Food

7.0

Reviews

1 / 20
2.0
Mediocre

Mike,Aug 2025

OKC - AUS

AC was not adequate, even on a night flight. WiFi subpar even for the airlines

Related info for your journey

Find useful and relevant information for your journey from Buffalo to Missouri. Access travel guides, tips, and recommendations to enhance your travel experience. Get information about local attractions, weather, transportation options, and more.

  • What airport do you fly from for flights from Buffalo to Missouri?

    Buffalo (BUF), located 8.3 mi from the city center, is the airport you fly out of when you book flights from Buffalo to Missouri.

  • How long is the flight from Buffalo to Missouri?

    A quick flight from Buffalo to Missouri can take about 4h 17m. American Airlines provides one of the quickest options available for as low as $246. Buffalo and Missouri are separated by a distance of 672 mi. This flight may include one or multiple stops.

  • What are the cheapest airlines to fly from Buffalo to Missouri one-way?

    To fly one-way, consider booking your trip with Southwest, which is currently one of the cheapest options available, starting at $77. Frontier flights start at $79 while deals on American Airlines start at $92 one-way.

  • What are the most popular routes from Buffalo to Missouri?

    While some choose either Buffalo - Lambert-St Louis or Buffalo - Springfield-Branson, Buffalo - Kansas City is the most popular route from Buffalo to Missouri.

  • Can I find deals for flights from Buffalo to Missouri that include hotel bookings?

    Yes. In addition to deals on Buffalo to Missouri flights, Cheapflights offers vacation packages that include both flights and hotel.

  • How can I find direct flights from Buffalo to Missouri?

    After entering your origin and destination, apply the non-stop filter on the search result page to find direct flights from Buffalo to Missouri.

  • Can I find deals for business class flights from Buffalo to Missouri?

    Yes. Cheapflights offers flight deals from Buffalo to Missouri by cabin class. In addition to browsing deals, you can also filter by cabin class on the search results page after making a search.

  • What is the cheapest month to book a flight from Buffalo to Missouri?

    Currently, August is the cheapest month in which you can book a flight from Buffalo to Missouri (average of $311). Flying from Buffalo to Missouri in March is currently the most expensive (average of $356). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.

See more FAQs

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Top 4 airlines flying from Buffalo to Missouri

Discover the top 4 airlines that operate flights from Buffalo to Missouri. Compare their services, reliability, and customer satisfaction ratings to choose the airline that best suits your travel preferences and needs. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated September 11, 2025.
AirlineCheapestAverageFlexibilityOn-time
SouthwestCheapest$236Average$406FlexibilityNo cancel feeOn-time63%
American AirlinesCheapest$236Average$379FlexibilityNo cancel feeOn-time71%
DeltaCheapest$243Average$356FlexibilityNo cancel feeOn-timeN/A
United AirlinesCheapest$293Average$642FlexibilityNo cancel feeOn-time69%

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