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$86+ Cheap flights from Buffalo (BUF) to Missouri

This is the cheapest one-way flight price found by a Cheapflights user in the last 72 hours by searching for a flight departing on 12/12. Fares are subject to change and may not be available on all flights or dates of travel.
BUF — STL
Nov 27 — Dec 41
Thu 11/27
Thu 12/4
1 adult, Economy
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Find flight deals from Buffalo to Missouri

Cheapest flights from Buffalo to Missouri
Explore the most affordable flight options available from Buffalo to Missouri. Find the lowest fares from popular airlines and budget airlines, with prices last updated on October 28, 2025.

This Booking.com deal was found by Cheapflights users on 10/27. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Booking.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 12/83:18 pmBUF - STL
1 stop8h 15mFrontier
Thu 12/113:30 pmSTL - BUF
1 stop19h 21mFrontier
Deal found 10/27$201
This Mytrip deal was found by Cheapflights users on 10/28. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Mytrip is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 11/79:53 pmBUF - STL
1 stop18h 45mFrontier
Sun 11/95:12 pmSTL - BUF
1 stop17h 32mFrontier
Deal found 10/28$211
This Gotogate deal was found by Cheapflights users on 10/27. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Gotogate is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 11/17:12 pmBUF - STL
1 stop20h 05mFrontier
Fri 11/72:12 pmSTL - BUF
1 stop27h 05mFrontier
Deal found 10/27$231
This Booking.com deal was found by Cheapflights users on 10/28. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Booking.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 12/1212:37 pmBUF - STL
1 stop10h 56mFrontier
Sun 12/143:30 pmSTL - BUF
1 stop21h 45mFrontier
Deal found 10/28$234
This American Airlines deal was found by Cheapflights users on 10/26. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 12/117:27 amBUF - SGF
1 stop7h 04mAmerican Airlines
Mon 12/157:00 amSGF - BUF
1 stop6h 20mAmerican Airlines
Deal found 10/26$248
This Southwest deal was found by Cheapflights users on 10/26. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 11/275:45 amBUF - STL
1 stop5h 05mSouthwest
Mon 12/86:05 amSTL - BUF
1 stop7h 15mSouthwest
Deal found 10/26$252
This Delta deal was found by Cheapflights users on 10/27. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 11/186:00 amBUF - STL
1 stop7h 40mDelta
Wed 11/199:35 amSTL - BUF
1 stop6h 25mDelta
Deal found 10/27$257
This Frontier deal was found by Cheapflights users on 10/27. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Frontier is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 11/202:01 pmBUF - MCI
1 stop19h 59mFrontier
Mon 11/2411:55 amMCI - BUF
1 stop24h 09mFrontier
Deal found 10/27$260
This United Airlines deal was found by Cheapflights users on 10/27. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 11/1810:50 amBUF - STL
1 stop5h 57mUnited Airlines
Wed 11/196:30 amSTL - BUF
2 stops6h 50mUnited Airlines
Deal found 10/27$262
This Kiwi.com deal was found by Cheapflights users on 10/27. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 11/202:01 pmBUF - MCI
2 stops30h 32mMultiple Airlines
Mon 11/246:00 amMCI - BUF
1 stop9h 20mMultiple Airlines
Deal found 10/27$271
This United Airlines deal was found by Cheapflights users on 10/27. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 12/36:00 amBUF - COU
2 stops9h 26mUnited Airlines
Wed 12/103:05 pmCOU - BUF
1 stop5h 10mUnited Airlines
Deal found 10/27$279
This American Airlines deal was found by Cheapflights users on 10/28. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 12/186:05 amBUF - SGF
1 stop4h 52mAmerican Airlines
Sun 12/213:42 pmSGF - BUF
1 stop5h 51mAmerican Airlines
Deal found 10/28$284

Cheap flight deals from Buffalo to Missouri

Keep the following information in mind while searching for Buffalo to Missouri flight deals. Data was last updated October 28, 2025.

Most accurate provider

eDreams
3 stars

Most trusted provider

eDreams
3 stars

Round-trip from

$201
(Booking.com)

One-way from

$86
(Trip.com)

Popular in

October

Cheapest in

September

Average price

$422
Provider with most accurate pricing for Buffalo-Lambert-St Louis flight deals.
Search Deals
Provider most trusted by Cheapflights users for Buffalo-Lambert-St Louis flights.
Search Deals
From Buffalo to Missouri
Search Deals
One-way flight from Buffalo to Missouri
Search Deals
High demand for flights, 1% potential price rise
Search Deals
Cheapest flight prices on average. 1% potential price decrease ($6 potential savings vs. average RT price).
Search Deals
Average for round-trip flights in October 2025
Search Deals

Cheapflights Fare Finder

 
Customize your flight search to find flights from Buffalo to Missouri that fit within your specific budget. Explore options based on user searches and filter the results based on your desired price range. Find flights that match your budget for a cost-effective journey. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated October 28, 2025.
Use the filters below to find and compare flights from Buffalo to Missouri that are best for you.

Fly from

Buffalo

Fly to

Missouri

Route

Depart

Return

Price

BuffaloSt. Louis

BUF - STL

BUFSTL

Buffalo

Mon 12/8

3:18 pm-10:33 pm

1 stop8h 15m

Lambert-St Louis

Thu 12/11

3:30 pm-11:51 am

1 stop19h 21m

$201

BuffaloSt. Louis

BUF - STL

BUFSTL

Buffalo

Fri 11/7

9:53 pm-3:38 pm

1 stop18h 45m

Lambert-St Louis

Sun 11/9

5:12 pm-11:44 am

1 stop17h 32m

$214

BuffaloSt. Louis

BUF - STL

BUFSTL

Buffalo

Fri 12/12

12:37 pm-10:33 pm

1 stop10h 56m

Lambert-St Louis

Sun 12/14

3:30 pm-2:15 pm

1 stop21h 45m

$234

BuffaloSpringfield

BUF - SGF

BUFSGF

Buffalo

Thu 12/11

7:27 am-1:31 pm

1 stop7h 04m

Springfield-Branson

Mon 12/15

7:00 am-2:20 pm

1 stop6h 20m

$248

BuffaloSt. Louis

BUF - STL

BUFSTL

Buffalo

Thu 11/27

5:45 am-9:50 am

1 stop5h 05m

Lambert-St Louis

Mon 12/8

6:05 am-2:20 pm

1 stop7h 15m

$252

BuffaloSt. Louis

BUF - STL

BUFSTL

Buffalo

Wed 1/14

12:07 pm-4:39 pm

1 stop5h 32m

Lambert-St Louis

Thu 1/15

6:25 am-2:10 pm

1 stop6h 45m

$257

BuffaloSt. Louis

BUF - STL

BUFSTL

Buffalo

Tue 11/18

6:00 am-12:40 pm

1 stop7h 40m

Lambert-St Louis

Wed 11/19

9:35 am-5:00 pm

1 stop6h 25m

$257

BuffaloSt. Louis

BUF - STL

BUFSTL

Buffalo

Tue 1/13

6:00 am-12:25 pm

1 stop7h 25m

Lambert-St Louis

Sun 1/18

6:35 am-11:24 am

1 stop3h 49m

$257

BuffaloSt. Louis

BUF - STL

BUFSTL

Buffalo

Tue 1/13

5:44 pm-8:45 pm

1 stop4h 01m

Lambert-St Louis

Thu 1/15

6:25 am-2:10 pm

1 stop6h 45m

$257

BuffaloSt. Louis

BUF - STL

BUFSTL

Buffalo

Thu 1/15

6:03 am-9:39 am

1 stop4h 36m

Lambert-St Louis

Mon 1/19

5:56 pm-10:59 pm

1 stop4h 03m

$257

Flights are sorted by cheapest round-trip flights first.

Deals found on 10/28

Showing 1-10 of 46 results
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Best time to book a flight from Buffalo to Missouri

Have a flexible travel schedule? Discover the best time to fly to Missouri from Buffalo with our price prediction graph.
Estimated round-trip price
Rates are based on past data. Find the cheapest month and day to book your flight based on your travel requirements, then search for cheap deals.

Cheapflights Insights

Everything you need to know about your flight from Buffalo to Missouri

What is the cheapest month to book a flight from Buffalo to Missouri?

Currently, August is the cheapest month in which you can book a flight from Buffalo to Missouri (average of $112). Flying from Buffalo to Missouri in December is currently the most expensive (average of $277). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.

What is the cheapest time of day to fly from BUF to MO?

Find hourly flight availability from Buffalo to Missouri. Discover flight options and departure times throughout the day, allowing you to choose a departure time that suits your schedule. Data last updated October 28, 2025.

Unlike in the morning, when flights are generally more expensive, you can save up to 23% on flights from Buffalo to Missouri by exploring options for tickets in the evening.

How much does it cost to fly round-trip from Buffalo to Missouri?

Reviews of airlines servicing Missouri

Get insights into the airlines that provide service to Missouri. Read reviews, discover amenities, and learn about the overall travel experience offered by airlines. Use this information to make informed decisions when choosing an airline for your flight to Missouri. Reviews last updated October 28, 2025.
Read through reviews of airlines operating flights from Buffalo to Missouri, such as Southwest, Delta, and United Airlines. You can also see how each airline stacks up in terms of entertainment options, comfort, food, crew/service, and boarding process.
Southwest
8.0
Very good
4,240 reviews

Boarding

8.1

Crew

8.6

Overall

8.0

Comfort

8.0

Food

7.0

Entertainment

7.5

Reviews

1 / 20
2.0
Mediocre

Mike,Aug 2025

OKC - AUS

AC was not adequate, even on a night flight. WiFi subpar even for the airlines
Southwest
8.0
Very good
4,240 reviews
Southwest
8.0
Very good
4,240 reviews

Boarding

8.1

Crew

8.6

Overall

8.0

Comfort

8.0

Food

7.0

Entertainment

7.5

Reviews

1 / 20
2.0
Mediocre

Mike,Aug 2025

OKC - AUS

AC was not adequate, even on a night flight. WiFi subpar even for the airlines
Delta
7.9
Good
7,994 reviews
Southwest
8.0
Very good
4,240 reviews

Boarding

8.1

Crew

8.6

Overall

8.0

Comfort

8.0

Food

7.0

Entertainment

7.5

Reviews

1 / 20
2.0
Mediocre

Mike,Aug 2025

OKC - AUS

AC was not adequate, even on a night flight. WiFi subpar even for the airlines
United Airlines
7.4
Good
9,001 reviews
Southwest
8.0
Very good
4,240 reviews

Boarding

8.1

Crew

8.6

Overall

8.0

Comfort

8.0

Food

7.0

Entertainment

7.5

Reviews

1 / 20
2.0
Mediocre

Mike,Aug 2025

OKC - AUS

AC was not adequate, even on a night flight. WiFi subpar even for the airlines
American Airlines
7.2
Good
11,032 reviews
Southwest
8.0
Very good
4,240 reviews

Boarding

8.1

Crew

8.6

Overall

8.0

Comfort

8.0

Food

7.0

Entertainment

7.5

Reviews

1 / 20
2.0
Mediocre

Mike,Aug 2025

OKC - AUS

AC was not adequate, even on a night flight. WiFi subpar even for the airlines

Related info for your journey

Find useful and relevant information for your journey from Buffalo to Missouri. Access travel guides, tips, and recommendations to enhance your travel experience. Get information about local attractions, weather, transportation options, and more.

  • What airport do you fly from for flights from Buffalo to Missouri?

    Buffalo (BUF), located 8.3 mi from the city center, is the airport you fly out of when you book flights from Buffalo to Missouri.

  • How long is the flight from Buffalo to Missouri?

    A quick flight from Buffalo to Missouri can take about 5h 05m. Frontier provides one of the quickest options available for as low as $252. Buffalo and Missouri are separated by a distance of 672 mi. This flight may include one or multiple stops.

  • What are the cheapest airlines to fly from Buffalo to Missouri one-way?

    To fly one-way, consider booking your trip with American Airlines, which is currently one of the cheapest options available, starting at $124. Delta flights start at $129 while deals on United Airlines start at $233 one-way.

  • What are the most popular routes from Buffalo to Missouri?

    While some choose either Buffalo - Lambert-St Louis or Buffalo - Springfield-Branson, Buffalo - Kansas City is the most popular route from Buffalo to Missouri.

  • Can I find deals for flights from Buffalo to Missouri that include hotel bookings?

    Yes. In addition to deals on Buffalo to Missouri flights, Cheapflights offers vacation packages that include both flights and hotel.

  • How can I find direct flights from Buffalo to Missouri?

    After entering your origin and destination, apply the non-stop filter on the search result page to find direct flights from Buffalo to Missouri.

  • Can I find deals for business class flights from Buffalo to Missouri?

    Yes. Cheapflights offers flight deals from Buffalo to Missouri by cabin class. In addition to browsing deals, you can also filter by cabin class on the search results page after making a search.

  • What is the cheapest month to book a flight from Buffalo to Missouri?

    Currently, August is the cheapest month in which you can book a flight from Buffalo to Missouri (average of $112). Flying from Buffalo to Missouri in December is currently the most expensive (average of $277). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.

See more FAQs

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Alternative routes for Buffalo to Missouri

See prices for flight routes from nearby airports that may be better suited for you.
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Top 4 airlines flying from Buffalo to Missouri

Discover the top 4 airlines that operate flights from Buffalo to Missouri. Compare their services, reliability, and customer satisfaction ratings to choose the airline that best suits your travel preferences and needs. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated October 28, 2025.
AirlineCheapestAverageFlexibilityOn-time
United AirlinesCheapest$198Average$562FlexibilityNo cancel feeOn-time69%
SouthwestCheapest$236Average$399FlexibilityNo cancel feeOn-time63%
DeltaCheapest$236Average$356FlexibilityNo cancel feeOn-timeN/A
American AirlinesCheapest$243Average$382FlexibilityNo cancel feeOn-time71%

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