$98+ Cheap flights from Buffalo (BUF) to Missouri
This is the cheapest one-way flight price found by a Cheapflights user in the last 72 hours by searching for a flight departing on 4/15. Fares are subject to change and may not be available on all flights or dates of travel.
BUF — STL
Apr 14 — Apr 211
Round-trip
1 adult, Economy
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Find cheap flights from Buffalo to Missouri with Cheapflights
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Cheapest flights from Buffalo to MissouriExplore the most affordable flight options available from Buffalo to Missouri. Find the lowest fares from popular airlines and budget airlines, with prices last updated on March 15, 2026.
Explore the most affordable flight options available from Buffalo to Missouri. Find the lowest fares from popular airlines and budget airlines, with prices last updated on March 15, 2026.
This Mytrip deal was found by Cheapflights users on 3/13. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Mytrip is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 4/109:05 pm
BUF
- STL
1 stop11h 46m
Frontier
Fri 4/174:59 pm
STL
- BUF
1 stop16h 50m
Frontier
Deal found 3/13![Frontier logo]()
$244
This Southwest deal was found by Cheapflights users on 3/13. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 5/46:15 am
BUF
- STL
1 stop8h 30m
Southwest
Wed 5/135:35 am
STL
- BUF
1 stop3h 45m
Southwest
Deal found 3/13![Southwest logo]()
$289
This Frontier deal was found by Cheapflights users on 3/13. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Frontier is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 4/2011:19 am
BUF
- STL
1 stop13h 00m
Frontier
Thu 4/234:59 pm
STL
- BUF
1 stop16h 08m
Frontier
Deal found 3/13![Frontier logo]()
$290
This American Airlines deal was found by Cheapflights users on 3/15. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 5/13:01 pm
BUF
- COU
1 stop7h 29m
American Airlines
Mon 5/44:28 pm
COU
- BUF
1 stop4h 08m
American Airlines
Deal found 3/15![American Airlines logo]()
$298
This American Airlines deal was found by Cheapflights users on 3/11. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 5/207:25 am
BUF
- COU
2 stops9h 33m
American Airlines
Sat 5/236:43 pm
COU
- BUF
1 stop4h 31m
American Airlines
Deal found 3/11![American Airlines logo]()
$304
This Southwest deal was found by Cheapflights users on 3/13. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 4/204:00 pm
BUF
- STL
2 stops8h 15m
Southwest
Thu 4/235:40 am
STL
- BUF
1 stop3h 35m
Southwest
Deal found 3/13![Southwest logo]()
$306
This American Airlines deal was found by Cheapflights users on 3/14. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 4/116:00 am
BUF
- STL
1 stop6h 47m
American Airlines
Sat 4/188:00 am
STL
- BUF
1 stop5h 21m
American Airlines
Deal found 3/14![American Airlines logo]()
$307
This American Airlines deal was found by Cheapflights users on 3/14. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 6/246:00 am
BUF
- SGF
1 stop5h 00m
American Airlines
Mon 6/292:21 pm
SGF
- BUF
1 stop6h 36m
American Airlines
Deal found 3/14![American Airlines logo]()
$309
This Kiwi.com deal was found by Cheapflights users on 3/15. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 5/1411:36 am
BUF
- STL
1 stop6h 18m
Frontier
Mon 5/185:27 pm
STL
- BUF
1 stop16h 14m
Frontier
Deal found 3/15![Frontier logo]()
$309
This Southwest deal was found by Cheapflights users on 3/14. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 4/113:40 pm
BUF
- STL
1 stop4h 30m
Southwest
Sat 4/186:10 am
STL
- BUF
2 stops9h 25m
Southwest
Deal found 3/14![Southwest logo]()
$314
This Southwest deal was found by Cheapflights users on 3/12. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 4/216:55 pm
BUF
- MCI
1 stop4h 35m
Southwest
Tue 4/285:25 am
MCI
- BUF
1 stop3h 55m
Southwest
Deal found 3/12![Southwest logo]()
$319
This American Airlines deal was found by Cheapflights users on 3/13. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 4/173:01 pm
BUF
- SGF
1 stop7h 04m
American Airlines
Sun 4/195:19 am
SGF
- BUF
1 stop4h 32m
American Airlines
Deal found 3/13![American Airlines logo]()
$322
Best flights from Buffalo to MissouriDiscover carefully curated flight deals from Buffalo to Missouri that have cost, travel time, and layovers in mind to ensure you get the best travel experience. Data last updated March 15, 2026.
Discover carefully curated flight deals from Buffalo to Missouri that have cost, travel time, and layovers in mind to ensure you get the best travel experience. Data last updated March 15, 2026.
This American Airlines deal was found by Cheapflights users on 3/11. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 5/16:00 am
BUF
- COU
1 stop4h 46m
American Airlines
Mon 5/46:00 am
COU
- BUF
1 stop7h 21m
American Airlines
Deal found 3/11![American Airlines logo]()
$298
This Southwest deal was found by Cheapflights users on 3/14. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 4/113:40 pm
BUF
- STL
1 stop4h 30m
Southwest
Sat 4/186:10 am
STL
- BUF
2 stops9h 25m
Southwest
Deal found 3/14![Southwest logo]()
$314
This United Airlines deal was found by Cheapflights users on 3/11. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 5/45:55 pm
BUF
- STL
1 stop4h 18m
United Airlines
Tue 5/59:21 am
STL
- BUF
1 stop6h 33m
United Airlines
Deal found 3/11![United Airlines logo]()
$359
This CheapOair deal was found by Cheapflights users on 3/10. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure CheapOair is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 6/511:55 am
BUF
- STL
1 stop13h 02m
Frontier
Sun 6/74:44 pm
STL
- BUF
1 stop18h 32m
Frontier
Deal found 3/10![Frontier logo]()
$362
This Delta deal was found by Cheapflights users on 3/14. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 5/68:56 am
BUF
- MCI
1 stop5h 28m
Delta
Sat 5/93:06 pm
MCI
- BUF
1 stop7h 53m
Delta
Deal found 3/14![Delta logo]()
$409
This American Airlines deal was found by Cheapflights users on 3/11. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 5/207:25 am
BUF
- COU
2 stops9h 33m
American Airlines
Sat 5/236:43 pm
COU
- BUF
1 stop4h 31m
American Airlines
Deal found 3/11![American Airlines logo]()
$304
This American Airlines deal was found by Cheapflights users on 3/14. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 4/116:00 am
BUF
- STL
1 stop6h 47m
American Airlines
Sat 4/188:00 am
STL
- BUF
1 stop5h 21m
American Airlines
Deal found 3/14![American Airlines logo]()
$307
This Southwest deal was found by Cheapflights users on 3/10. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 5/136:55 pm
BUF
- MCI
1 stop4h 35m
Southwest
Sun 5/175:25 am
MCI
- BUF
1 stop4h 00m
Southwest
Deal found 3/10![Southwest logo]()
$353
This United Airlines deal was found by Cheapflights users on 3/12. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 4/176:02 pm
BUF
- MCI
1 stop4h 57m
United Airlines
Tue 4/288:00 am
MCI
- BUF
2 stops9h 49m
United Airlines
Deal found 3/12![United Airlines logo]()
$368
This American Airlines deal was found by Cheapflights users on 3/13. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 4/173:01 pm
BUF
- SGF
1 stop7h 04m
American Airlines
Sun 4/195:19 am
SGF
- BUF
1 stop4h 32m
American Airlines
Deal found 3/13![American Airlines logo]()
$322
This United Airlines deal was found by Cheapflights users on 3/10. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 4/1810:45 am
BUF
- COU
2 stops12h 16m
United Airlines
Wed 4/223:23 pm
COU
- BUF
1 stop4h 20m
United Airlines
Deal found 3/10![United Airlines logo]()
$374
This Southwest deal was found by Cheapflights users on 3/14. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 6/46:05 am
BUF
- MCI
2 stops6h 55m
Southwest
Tue 6/91:40 pm
MCI
- BUF
2 stops6h 45m
Southwest
Deal found 3/14![Southwest logo]()
$375
This Southwest deal was found by Cheapflights users on 3/10. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 6/52:50 pm
BUF
- STL
2 stops7h 00m
Southwest
Sun 6/78:00 pm
STL
- BUF
1 stop11h 10m
Southwest
Deal found 3/10![Southwest logo]()
$378
This American Airlines deal was found by Cheapflights users on 3/12. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 4/307:00 am
BUF
- STL
1 stop5h 09m
American Airlines
Sun 5/37:05 am
STL
- BUF
1 stop6h 16m
American Airlines
Deal found 3/12![American Airlines logo]()
$344
This United Airlines deal was found by Cheapflights users on 3/13. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 4/187:00 am
BUF
- COU
1 stop4h 55m
United Airlines
Tue 4/213:23 pm
COU
- BUF
1 stop4h 20m
United Airlines
Deal found 3/13![United Airlines logo]()
$388
This Delta deal was found by Cheapflights users on 3/14. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 6/224:30 pm
BUF
- SGF
1 stop7h 05m
Delta
Tue 6/303:35 pm
SGF
- BUF
1 stop7h 23m
Delta
Deal found 3/14![Delta logo]()
$499
This Southwest deal was found by Cheapflights users on 3/12. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 4/218:20 am
BUF
- MCI
2 stops7h 15m
Southwest
Tue 4/282:10 pm
MCI
- BUF
2 stops5h 15m
Southwest
Deal found 3/12![Southwest logo]()
$383
This American Airlines deal was found by Cheapflights users on 3/15. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 6/168:00 am
BUF
- STL
1 stop6h 15m
American Airlines
Fri 6/193:12 pm
STL
- BUF
1 stop5h 11m
American Airlines
Deal found 3/15![American Airlines logo]()
$369
This Southwest deal was found by Cheapflights users on 3/11. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 5/144:00 pm
BUF
- MCI
2 stops8h 00m
Southwest
Sun 5/175:25 am
MCI
- BUF
1 stop4h 00m
Southwest
Deal found 3/11![Southwest logo]()
$391
This Delta deal was found by Cheapflights users on 3/14. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 6/254:30 pm
BUF
- SGF
1 stop7h 05m
Delta
Mon 6/296:45 pm
SGF
- BUF
2 stops18h 54m
Delta
Deal found 3/14![Delta logo]()
$527
This United Airlines deal was found by Cheapflights users on 3/11. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 3/277:00 am
BUF
- SGF
1 stop4h 46m
United Airlines
Tue 3/318:00 am
SGF
- BUF
1 stop4h 13m
United Airlines
Deal found 3/11![United Airlines logo]()
$472
This Southwest deal was found by Cheapflights users on 3/14. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 5/64:00 pm
BUF
- MCI
2 stops7h 30m
Southwest
Sun 5/102:35 pm
MCI
- BUF
2 stops5h 50m
Southwest
Deal found 3/14![Southwest logo]()
$392
This American Airlines deal was found by Cheapflights users on 3/10. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 4/1711:31 am
BUF
- MCI
1 stop5h 16m
American Airlines
Tue 4/217:05 am
MCI
- BUF
2 stops8h 37m
American Airlines
Deal found 3/10![American Airlines logo]()
$410
This Southwest deal was found by Cheapflights users on 3/12. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 5/134:00 pm
BUF
- MCI
1 stop6h 30m
Southwest
Wed 5/2011:55 am
MCI
- BUF
2 stops7h 30m
Southwest
Deal found 3/12![Southwest logo]()
$394
This United Airlines deal was found by Cheapflights users on 3/14. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 6/255:52 pm
BUF
- SGF
1 stop5h 01m
United Airlines
Mon 6/293:07 pm
SGF
- BUF
1 stop4h 34m
United Airlines
Deal found 3/14![United Airlines logo]()
$499
This Delta deal was found by Cheapflights users on 3/14. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 6/236:25 am
BUF
- SGF
2 stops12h 45m
Delta
Mon 6/296:00 am
SGF
- BUF
2 stops16h 03m
Delta
Deal found 3/14![Delta logo]()
$612
This Southwest deal was found by Cheapflights users on 3/13. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 5/218:00 pm
BUF
- MCI
1 stop4h 00m
Southwest
Sun 5/2412:20 pm
MCI
- BUF
2 stops7h 15m
Southwest
Deal found 3/13![Southwest logo]()
$422
This American Airlines deal was found by Cheapflights users on 3/10. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 3/286:00 am
BUF
- SGF
1 stop4h 53m
American Airlines
Wed 4/14:47 pm
SGF
- BUF
1 stop5h 41m
American Airlines
Deal found 3/10![American Airlines logo]()
$479
This United Airlines deal was found by Cheapflights users on 3/14. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 6/245:52 pm
BUF
- SGF
1 stop4h 56m
United Airlines
Sun 6/283:07 pm
SGF
- BUF
1 stop4h 34m
United Airlines
Deal found 3/14![United Airlines logo]()
$527
This American Airlines deal was found by Cheapflights users on 3/13. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 6/16:25 am
BUF
- SGF
1 stop5h 32m
American Airlines
Fri 6/52:21 pm
SGF
- BUF
1 stop6h 36m
American Airlines
Deal found 3/13![American Airlines logo]()
$537
Last-minute flights from Buffalo to MissouriDiscover last-minute flight deals from Buffalo to Missouri. Data last updated March 15, 2026 and is based on user searches.
Discover last-minute flight deals from Buffalo to Missouri. Data last updated March 15, 2026 and is based on user searches.
This Mytrip deal was found by Cheapflights users on 3/12. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Mytrip is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 3/169:25 pm
BUF
- STL
1 stop26h 54m
Frontier
Wed 3/254:51 pm
STL
- BUF
1 stop16h 58m
Frontier
Deal found 3/12![Frontier logo]()
$340
This Southwest deal was found by Cheapflights users on 3/13. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 4/86:55 pm
BUF
- STL
1 stop4h 15m
Southwest
Mon 4/137:45 pm
STL
- BUF
1 stop11h 05m
Southwest
Deal found 3/13![Southwest logo]()
$326
This Kiwi.com deal was found by Cheapflights users on 3/13. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 4/811:12 am
BUF
- STL
1 stop13h 13m
Frontier
Mon 4/138:19 pm
STL
- BUF
2 stops39h 33m
Frontier
Deal found 3/13![Frontier logo]()
$341
This Mytrip deal was found by Cheapflights users on 3/13. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Mytrip is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 4/109:05 pm
BUF
- STL
1 stop11h 46m
Frontier
Fri 4/174:59 pm
STL
- BUF
1 stop16h 50m
Frontier
Deal found 3/13![Frontier logo]()
$244
This American Airlines deal was found by Cheapflights users on 3/14. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 4/116:00 am
BUF
- STL
1 stop6h 47m
American Airlines
Sat 4/188:00 am
STL
- BUF
1 stop5h 21m
American Airlines
Deal found 3/14![American Airlines logo]()
$307
This Southwest deal was found by Cheapflights users on 3/14. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 4/113:40 pm
BUF
- STL
1 stop4h 30m
Southwest
Sat 4/186:10 am
STL
- BUF
2 stops9h 25m
Southwest
Deal found 3/14![Southwest logo]()
$314
This American Airlines deal was found by Cheapflights users on 3/13. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 4/173:01 pm
BUF
- SGF
1 stop7h 04m
American Airlines
Sun 4/195:19 am
SGF
- BUF
1 stop4h 32m
American Airlines
Deal found 3/13![American Airlines logo]()
$322
This Frontier deal was found by Cheapflights users on 3/13. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Frontier is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 4/2011:19 am
BUF
- STL
1 stop13h 00m
Frontier
Thu 4/234:59 pm
STL
- BUF
1 stop16h 08m
Frontier
Deal found 3/13![Frontier logo]()
$290
This Southwest deal was found by Cheapflights users on 3/13. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 4/204:00 pm
BUF
- STL
2 stops8h 15m
Southwest
Thu 4/235:40 am
STL
- BUF
1 stop3h 35m
Southwest
Deal found 3/13![Southwest logo]()
$306
This Southwest deal was found by Cheapflights users on 3/12. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 4/216:55 pm
BUF
- MCI
1 stop4h 35m
Southwest
Tue 4/285:25 am
MCI
- BUF
1 stop3h 55m
Southwest
Deal found 3/12![Southwest logo]()
$319
This Southwest deal was found by Cheapflights users on 3/12. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 4/238:00 pm
BUF
- STL
1 stop3h 45m
Southwest
Sun 4/265:25 am
STL
- BUF
1 stop4h 00m
Southwest
Deal found 3/12![Southwest logo]()
$344
This Southwest deal was found by Cheapflights users on 3/11. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 4/294:00 pm
BUF
- MCI
2 stops7h 30m
Southwest
Tue 5/58:25 am
MCI
- BUF
2 stops5h 55m
Southwest
Deal found 3/11![Southwest logo]()
$339
One-way flights from Buffalo to MissouriSearch for one-way flight options from Buffalo to Missouri. Find affordable one-way fares based on user searches. Data last updated March 15, 2026.
Search for one-way flight options from Buffalo to Missouri. Find affordable one-way fares based on user searches. Data last updated March 15, 2026.
This Kiwi.com deal was found by Cheapflights users on 3/14. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 4/151:56 pm
BUF
- STL
1 stop21h 34m
Frontier
Deal found 3/14![Frontier logo]()
$98
This Priceline deal was found by Cheapflights users on 3/13. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Priceline is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 5/3012:41 pm
BUF
- MCI
1 stop5h 48m
Frontier
Deal found 3/13![Frontier logo]()
$111
This Southwest deal was found by Cheapflights users on 3/14. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 4/294:00 pm
BUF
- STL
2 stops7h 10m
Southwest
Deal found 3/14![Southwest logo]()
$154
This American Airlines deal was found by Cheapflights users on 3/11. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 5/136:00 am
BUF
- MCI
1 stop5h 18m
American Airlines
Deal found 3/11![American Airlines logo]()
$160
This Kiwi.com deal was found by Cheapflights users on 3/11. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 4/11:02 pm
BUF
- STL
1 stop29h 32m
Frontier
Deal found 3/11![Frontier logo]()
$164
This Southwest deal was found by Cheapflights users on 3/11. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 6/24:00 pm
BUF
- MCI
2 stops7h 30m
Southwest
Deal found 3/11![Southwest logo]()
$165
This United Airlines deal was found by Cheapflights users on 3/12. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 5/77:00 am
BUF
- MCI
1 stop4h 33m
United Airlines
Deal found 3/12![United Airlines logo]()
$173
This Kiwi.com deal was found by Cheapflights users on 3/14. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 4/51:02 pm
BUF
- MCI
1 stop27h 34m
Frontier
Deal found 3/14![Frontier logo]()
$175
This American Airlines deal was found by Cheapflights users on 3/11. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 5/156:00 pm
BUF
- STL
1 stop6h 56m
American Airlines
Deal found 3/11![American Airlines logo]()
$184
This Kiwi.com deal was found by Cheapflights users on 3/12. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 4/121:02 pm
BUF
- MCI
1 stop27h 34m
Frontier
Deal found 3/12![Frontier logo]()
$186
This Kiwi.com deal was found by Cheapflights users on 3/14. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 6/1411:55 am
BUF
- STL
1 stop13h 02m
Frontier
Deal found 3/14![Frontier logo]()
$186
This American Airlines deal was found by Cheapflights users on 3/10. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 5/3010:38 am
BUF
- MCI
1 stop7h 00m
American Airlines
Deal found 3/10![American Airlines logo]()
$194
Find flight deals from Buffalo to Missouri
Keep the following information in mind while searching for Buffalo to Missouri flight deals. Data was last updated March 15, 2026.
Most accurate provider | FlightHub 3 stars |
|---|---|
Most trusted provider | FlightHub 3 stars |
Round-trip from | $244 (Mytrip) |
One-way from | $98 (Kiwi.com) |
Popular in | March |
Cheapest in | September |
Average price | $575 |
Cheapflights Fare Finder
Customize your flight search to find flights from Buffalo to Missouri that fit within your specific budget. Explore options based on user searches and filter the results based on your desired price range. Find flights that match your budget for a cost-effective journey. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated March 15, 2026.
Use the filters below to find and compare flights from Buffalo to Missouri that are best for you.
Fly from
Fly to
Route
Depart
Return
Cheapest round-trip
BuffaloColumbia
BUF - COU
BUFCOU
Buffalo
Fri 5/1
6:00 am-9:46 am
1 stop4h 46m
Columbia Regional
Mon 5/4
6:00 am-2:21 pm
1 stop7h 21m
$298
BuffaloColumbia
BUF - COU
BUFCOU
Buffalo
Wed 5/20
7:25 am-3:58 pm
2 stops9h 33m
Columbia Regional
Sat 5/23
6:43 pm-12:14 am
1 stop4h 31m
$304
BuffaloSt. Louis
BUF - STL
BUFSTL
Buffalo
Sat 4/11
6:00 am-11:47 am
1 stop6h 47m
Lambert-St Louis
Sat 4/18
8:00 am-2:21 pm
1 stop5h 21m
$307
BuffaloSt. Louis
BUF - STL
BUFSTL
Buffalo
Sat 4/11
3:40 pm-7:10 pm
1 stop4h 30m
Lambert-St Louis
Sat 4/18
6:10 am-4:35 pm
2 stops9h 25m
$314
BuffaloSpringfield
BUF - SGF
BUFSGF
Buffalo
Fri 4/17
3:01 pm-9:05 pm
1 stop7h 04m
Springfield-Branson
Sun 4/19
5:19 am-10:51 am
1 stop4h 32m
$322
BuffaloSt. Louis
BUF - STL
BUFSTL
Buffalo
Thu 4/30
7:00 am-11:09 am
1 stop5h 09m
Lambert-St Louis
Sun 5/3
7:05 am-2:21 pm
1 stop6h 16m
$344
Quickest round-trip
BuffaloKansas City
BUF - MCI
BUFMCI
Buffalo
Wed 5/13
6:55 pm-10:30 pm
1 stop4h 35m
Kansas City
Sun 5/17
5:25 am-10:25 am
1 stop4h 00m
$353
BuffaloSt. Louis
BUF - STL
BUFSTL
Buffalo
Mon 5/4
5:55 pm-9:13 pm
1 stop4h 18m
Lambert-St Louis
Tue 5/5
9:21 am-4:54 pm
1 stop6h 33m
$359
BuffaloSt. Louis
BUF - STL
BUFSTL
Buffalo
Fri 6/5
11:55 am-11:57 pm
1 stop13h 02m
Lambert-St Louis
Sun 6/7
4:44 pm-12:16 pm
1 stop18h 32m
$362
BuffaloKansas City
BUF - MCI
BUFMCI
Buffalo
Fri 4/17
6:02 pm-9:59 pm
1 stop4h 57m
Kansas City
Tue 4/28
8:00 am-6:49 pm
2 stops9h 49m
$368
Showing 1-10 of 51 resultsSorted by cheapest first
Best time to book a flight from Buffalo to Missouri
Have a flexible travel schedule? Discover the best time to fly to Missouri from Buffalo with our price prediction graph.
BUF-STL
BUF-MCI
BUF-SGF
BUF-COU
Estimated round-trip price
Rates are based on past data. Find the cheapest month and day to book your flight based on your travel requirements, then search for cheap deals.
Cheapflights Insights
Everything you need to know about your flight from Buffalo to Missouri
BUF-USMO
BUF-STL
BUF-MCI
BUF-SGF
BUF-COU
What is the cheapest month to book a flight from Buffalo to Missouri?
Currently, August is the cheapest month in which you can book a flight from Buffalo to Missouri (average of $112). Flying from Buffalo to Missouri in February is currently the most expensive (average of $277). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.
Reviews of airlines servicing Missouri
Get insights into the airlines that provide service to Missouri. Read reviews, discover amenities, and learn about the overall travel experience offered by airlines. Use this information to make informed decisions when choosing an airline for your flight to Missouri. Reviews last updated March 15, 2026.
Read through reviews of airlines operating flights from Buffalo to Missouri, such as Southwest,Delta, andUnited Airlines. You can also see how each airline stacks up in terms of entertainment options, comfort, food, crew/service, and boarding process.
Food
7.0
Crew
8.6
Entertainment
7.5
Comfort
8.0
Overall
8.0
Boarding
8.1
Reviews
1 / 20
10.0
ExcellentAnonymous,Mar 2026
KOA - HNL
Food
7.0
Crew
8.6
Entertainment
7.5
Comfort
8.0
Overall
8.0
Boarding
8.1
Reviews
1 / 20
10.0
ExcellentAnonymous,Mar 2026
KOA - HNL
Food
7.0
Crew
8.6
Entertainment
7.5
Comfort
8.0
Overall
8.0
Boarding
8.1
Reviews
1 / 20
10.0
ExcellentAnonymous,Mar 2026
KOA - HNL
Food
7.0
Crew
8.6
Entertainment
7.5
Comfort
8.0
Overall
8.0
Boarding
8.1
Reviews
1 / 20
10.0
ExcellentAnonymous,Mar 2026
KOA - HNL
Food
7.0
Crew
8.6
Entertainment
7.5
Comfort
8.0
Overall
8.0
Boarding
8.1
Reviews
1 / 20
10.0
ExcellentAnonymous,Mar 2026
KOA - HNL
Related info for your journey
Find useful and relevant information for your journey from Buffalo to Missouri. Access travel guides, tips, and recommendations to enhance your travel experience. Get information about local attractions, weather, transportation options, and more.
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Complete your trip
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Find flights from Buffalo to Missouri, based on your preferred cabin class, be it economy, premium economy, business, or first class.
Buffalo and Missouri flights
Browse other Buffalo and Missouri flight options. Last updated on March 15, 2026.
Popular flight searches
Check out other popular destinations found by fellow travelers in 2026
Buffalo to Missouri flights
Consider these flights traveling from Buffalo to Missouri.
Top 4 airlines flying from Buffalo to Missouri
Discover the top 4 airlines that operate flights from Buffalo to Missouri. Compare their services, reliability, and customer satisfaction ratings to choose the airline that best suits your travel preferences and needs. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated March 15, 2026.
| Airline | Cheapest | Average | Flexibility | On-time |
|---|---|---|---|---|
| Cheapest$164 | Average$356 | FlexibilityNo cancel fee | On-timeN/A | |
| Cheapest$197 | Average$373 | FlexibilityNo cancel fee | On-time71% | |
| Cheapest$236 | Average$422 | FlexibilityNo cancel fee | On-time63% | |
| Cheapest$294 | Average$392 | FlexibilityNo cancel fee | On-time69% |