$94+ Cheap flights from Missouri to Buffalo (BUF)
This is the cheapest one-way flight price found by a Cheapflights user in the last 72 hours by searching for a flight departing on 8/24. Fares are subject to change and may not be available on all flights or dates of travel.
MCI — BUF
Jul 10 — Jul 171
Round-trip
1 adult, Economy
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Cheapest flights from Missouri to BuffaloExplore the most affordable flight options available from Missouri to Buffalo. Find the lowest fares from popular airlines and budget airlines, with prices last updated on June 10, 2026.
Explore the most affordable flight options available from Missouri to Buffalo. Find the lowest fares from popular airlines and budget airlines, with prices last updated on June 10, 2026.
This Kiwi.com deal was found by Cheapflights users on 6/9. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 8/46:34 pm
STL
- BUF
1 stop18h 19m
Frontier
Fri 8/72:48 pm
BUF
- STL
1 stop19h 09m
Frontier
Deal found 6/9![Frontier logo]()
$186
This Kiwi.com deal was found by Cheapflights users on 6/9. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 7/76:34 pm
STL
- BUF
1 stop18h 19m
Frontier
Tue 7/1411:29 am
BUF
- STL
1 stop7h 08m
Frontier
Deal found 6/9![Frontier logo]()
$187
This Kiwi.com deal was found by Cheapflights users on 6/5. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 7/146:34 pm
STL
- BUF
1 stop18h 19m
Frontier
Fri 7/242:48 pm
BUF
- STL
1 stop19h 09m
Frontier
Deal found 6/5![Frontier logo]()
$188
This Kiwi.com deal was found by Cheapflights users on 6/6. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 8/116:34 pm
STL
- BUF
1 stop18h 19m
Frontier
Fri 8/142:48 pm
BUF
- STL
1 stop19h 09m
Frontier
Deal found 6/6![Frontier logo]()
$191
This Kiwi.com deal was found by Cheapflights users on 6/8. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 7/156:07 pm
MCI
- BUF
1 stop15h 22m
Frontier
Fri 7/172:48 pm
BUF
- MCI
1 stop27h 22m
Frontier
Deal found 6/8![Frontier logo]()
$191
This Kiwi.com deal was found by Cheapflights users on 6/5. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 7/64:57 pm
STL
- BUF
1 stop16h 32m
Frontier
Fri 7/102:48 pm
BUF
- STL
1 stop19h 09m
Frontier
Deal found 6/5![Frontier logo]()
$200
This Kiwi.com deal was found by Cheapflights users on 6/9. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 7/256:07 pm
MCI
- BUF
1 stop15h 22m
Frontier
Sat 8/112:28 pm
BUF
- MCI
1 stop5h 42m
Frontier
Deal found 6/9![Frontier logo]()
$209
This Kiwi.com deal was found by Cheapflights users on 6/8. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 7/204:57 pm
STL
- BUF
1 stop16h 32m
Frontier
Thu 7/2311:29 am
BUF
- STL
1 stop7h 08m
Frontier
Deal found 6/8![Frontier logo]()
$211
This Kiwi.com deal was found by Cheapflights users on 6/5. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 7/204:57 pm
STL
- BUF
1 stop16h 32m
Frontier
Wed 7/222:48 pm
BUF
- STL
1 stop27h 49m
Frontier
Deal found 6/5![Frontier logo]()
$215
This Delta deal was found by Cheapflights users on 6/10. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 9/306:40 am
STL
- BUF
1 stop3h 37m
Delta
Tue 10/139:00 am
BUF
- STL
1 stop5h 20m
Delta
Deal found 6/10![Delta logo]()
$221
This Kiwi.com deal was found by Cheapflights users on 6/5. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 7/244:57 pm
STL
- BUF
1 stop17h 36m
Frontier
Mon 7/272:48 pm
BUF
- STL
1 stop27h 49m
Frontier
Deal found 6/5![Frontier logo]()
$225
This Kiwi.com deal was found by Cheapflights users on 6/9. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 7/204:57 pm
STL
- BUF
1 stop16h 32m
Frontier
Mon 7/272:48 pm
BUF
- STL
1 stop27h 49m
Frontier
Deal found 6/9![Frontier logo]()
$228
Best flights from Missouri to BuffaloDiscover carefully curated flight deals from Missouri to Buffalo that have cost, travel time, and layovers in mind to ensure you get the best travel experience. Data last updated June 10, 2026.
Discover carefully curated flight deals from Missouri to Buffalo that have cost, travel time, and layovers in mind to ensure you get the best travel experience. Data last updated June 10, 2026.
This Southwest deal was found by Cheapflights users on 6/8. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 10/36:30 am
STL
- BUF
1 stop6h 40m
Southwest
Tue 10/67:30 am
BUF
- STL
2 stops7h 20m
Southwest
Deal found 6/8![Southwest logo]()
$251
This Kiwi.com deal was found by Cheapflights users on 6/9. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 7/66:07 pm
MCI
- BUF
1 stop15h 22m
Frontier
Sat 7/1112:28 pm
BUF
- MCI
1 stop5h 42m
Frontier
Deal found 6/9![Frontier logo]()
$265
This Delta deal was found by Cheapflights users on 6/6. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 9/296:40 am
STL
- BUF
1 stop3h 37m
Delta
Tue 10/1312:50 pm
BUF
- STL
1 stop5h 00m
Delta
Deal found 6/6![Delta logo]()
$275
This United Airlines deal was found by Cheapflights users on 6/6. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 9/306:00 am
STL
- BUF
2 stops7h 23m
United Airlines
Tue 10/135:45 pm
BUF
- STL
1 stop4h 36m
United Airlines
Deal found 6/6![United Airlines logo]()
$280
This American Airlines deal was found by Cheapflights users on 6/7. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 6/267:53 pm
SGF
- BUF
1 stop12h 36m
American Airlines
Wed 7/18:06 am
BUF
- SGF
1 stop15h 34m
American Airlines
Deal found 6/7![American Airlines logo]()
$546
This Southwest deal was found by Cheapflights users on 6/5. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 9/156:30 am
MCI
- BUF
1 stop6h 50m
Southwest
Wed 9/163:00 pm
BUF
- MCI
1 stop6h 10m
Southwest
Deal found 6/5![Southwest logo]()
$315
This Kiwi.com deal was found by Cheapflights users on 6/5. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 6/265:06 pm
STL
- BUF
1 stop17h 28m
Frontier
Tue 6/309:02 pm
BUF
- STL
2 stops22h 16m
Frontier
Deal found 6/5![Frontier logo]()
$338
This United Airlines deal was found by Cheapflights users on 6/9. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 9/112:59 pm
STL
- BUF
1 stop7h 08m
United Airlines
Wed 9/210:30 am
BUF
- STL
1 stop6h 08m
United Airlines
Deal found 6/9![United Airlines logo]()
$342
This Southwest deal was found by Cheapflights users on 6/8. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 7/96:05 pm
MCI
- BUF
1 stop5h 10m
Southwest
Thu 7/167:55 pm
BUF
- MCI
1 stop4h 25m
Southwest
Deal found 6/8![Southwest logo]()
$315
This Delta deal was found by Cheapflights users on 6/5. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 7/295:40 pm
MCI
- BUF
1 stop5h 18m
Delta
Tue 8/47:52 pm
BUF
- MCI
1 stop4h 35m
Delta
Deal found 6/5![Delta logo]()
$357
This Southwest deal was found by Cheapflights users on 6/8. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 10/36:00 am
STL
- BUF
2 stops7h 10m
Southwest
Mon 10/54:00 pm
BUF
- STL
2 stops7h 35m
Southwest
Deal found 6/8![Southwest logo]()
$320
This United Airlines deal was found by Cheapflights users on 6/7. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 8/3010:55 am
COU
- BUF
1 stop5h 01m
United Airlines
Sat 9/55:58 pm
BUF
- COU
1 stop5h 57m
United Airlines
Deal found 6/7![United Airlines logo]()
$358
This Delta deal was found by Cheapflights users on 6/6. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 8/1211:38 am
SGF
- BUF
1 stop6h 17m
Delta
Wed 8/194:13 pm
BUF
- SGF
1 stop7h 08m
Delta
Deal found 6/6![Delta logo]()
$390
This United Airlines deal was found by Cheapflights users on 6/8. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 7/1411:25 am
STL
- BUF
2 stops11h 34m
United Airlines
Wed 7/156:04 pm
BUF
- STL
1 stop4h 22m
United Airlines
Deal found 6/8![United Airlines logo]()
$360
This United Airlines deal was found by Cheapflights users on 6/8. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 7/141:03 pm
MCI
- BUF
2 stops9h 56m
United Airlines
Wed 7/2210:57 am
BUF
- MCI
1 stop6h 03m
United Airlines
Deal found 6/8![United Airlines logo]()
$360
This Southwest deal was found by Cheapflights users on 6/6. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 10/78:30 am
MCI
- BUF
2 stops6h 25m
Southwest
Mon 10/127:05 pm
BUF
- MCI
1 stop6h 30m
Southwest
Deal found 6/6![Southwest logo]()
$360
This Delta deal was found by Cheapflights users on 6/8. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 8/273:20 pm
SGF
- BUF
1 stop7h 39m
Delta
Mon 8/316:05 am
BUF
- SGF
1 stop5h 48m
Delta
Deal found 6/8![Delta logo]()
$405
This United Airlines deal was found by Cheapflights users on 6/9. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 8/181:08 pm
MCI
- BUF
1 stop6h 59m
United Airlines
Wed 8/195:58 pm
BUF
- MCI
1 stop4h 46m
United Airlines
Deal found 6/9![United Airlines logo]()
$370
This Southwest deal was found by Cheapflights users on 6/5. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 7/213:15 pm
STL
- BUF
2 stops6h 30m
Southwest
Thu 7/235:55 pm
BUF
- STL
2 stops7h 45m
Southwest
Deal found 6/5![Southwest logo]()
$382
This Delta deal was found by Cheapflights users on 6/6. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 7/111:38 am
SGF
- BUF
2 stops12h 00m
Delta
Tue 7/76:05 am
BUF
- SGF
2 stops9h 35m
Delta
Deal found 6/6![Delta logo]()
$439
This United Airlines deal was found by Cheapflights users on 6/9. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 9/110:55 am
COU
- BUF
1 stop5h 01m
United Airlines
Sat 9/510:30 am
BUF
- COU
1 stop5h 00m
United Airlines
Deal found 6/9![United Airlines logo]()
$378
This Southwest deal was found by Cheapflights users on 6/10. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 7/104:35 pm
STL
- BUF
2 stops6h 40m
Southwest
Wed 7/156:00 am
BUF
- STL
2 stops8h 05m
Southwest
Deal found 6/10![Southwest logo]()
$386
This Delta deal was found by Cheapflights users on 6/7. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 7/73:26 pm
SGF
- BUF
1 stop7h 33m
Delta
Fri 7/315:12 pm
BUF
- SGF
1 stop5h 58m
Delta
Deal found 6/7![Delta logo]()
$479
This United Airlines deal was found by Cheapflights users on 6/5. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 6/233:25 pm
COU
- BUF
1 stop4h 38m
United Airlines
Sat 6/276:04 pm
BUF
- COU
1 stop6h 29m
United Airlines
Deal found 6/5![United Airlines logo]()
$403
This Southwest deal was found by Cheapflights users on 6/6. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 10/48:25 am
MCI
- BUF
1 stop6h 05m
Southwest
Thu 10/87:05 pm
BUF
- MCI
1 stop6h 30m
Southwest
Deal found 6/6![Southwest logo]()
$407
This United Airlines deal was found by Cheapflights users on 6/9. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 11/51:45 pm
MCI
- BUF
1 stop8h 00m
United Airlines
Sun 11/810:50 am
BUF
- MCI
1 stop6h 34m
United Airlines
Deal found 6/9![United Airlines logo]()
$405
This Delta deal was found by Cheapflights users on 6/6. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 8/136:06 am
SGF
- BUF
2 stops16h 23m
Delta
Mon 8/176:05 am
BUF
- SGF
1 stop5h 48m
Delta
Deal found 6/6![Delta logo]()
$491
This Delta deal was found by Cheapflights users on 6/6. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 8/1411:38 am
SGF
- BUF
2 stops10h 51m
Delta
Wed 8/1912:02 pm
BUF
- SGF
2 stops11h 19m
Delta
Deal found 6/6![Delta logo]()
$513
This United Airlines deal was found by Cheapflights users on 6/7. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 8/2910:55 am
COU
- BUF
1 stop5h 01m
United Airlines
Sun 9/610:30 am
BUF
- COU
1 stop5h 00m
United Airlines
Deal found 6/7![United Airlines logo]()
$433
This United Airlines deal was found by Cheapflights users on 6/5. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 6/2710:49 am
COU
- BUF
1 stop4h 52m
United Airlines
Sun 6/287:00 am
BUF
- COU
1 stop4h 13m
United Airlines
Deal found 6/5![United Airlines logo]()
$448
Last-minute flights from Missouri to BuffaloDiscover last-minute flight deals from Missouri to Buffalo. Data last updated June 10, 2026 and is based on user searches.
Discover last-minute flight deals from Missouri to Buffalo. Data last updated June 10, 2026 and is based on user searches.
This Kiwi.com deal was found by Cheapflights users on 6/5. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 6/265:06 pm
STL
- BUF
1 stop17h 28m
Frontier
Tue 6/3011:50 am
BUF
- STL
1 stop6h 40m
Frontier
Deal found 6/5![Frontier logo]()
$242
This Kiwi.com deal was found by Cheapflights users on 6/6. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 7/35:06 pm
STL
- BUF
1 stop17h 28m
Frontier
Thu 7/911:29 am
BUF
- STL
1 stop7h 08m
Frontier
Deal found 6/6![Frontier logo]()
$233
This Kiwi.com deal was found by Cheapflights users on 6/5. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 7/64:57 pm
STL
- BUF
1 stop16h 32m
Frontier
Fri 7/102:48 pm
BUF
- STL
1 stop19h 09m
Frontier
Deal found 6/5![Frontier logo]()
$200
This Kiwi.com deal was found by Cheapflights users on 6/9. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 7/66:07 pm
MCI
- BUF
1 stop15h 22m
Frontier
Sat 7/1112:28 pm
BUF
- MCI
1 stop5h 42m
Frontier
Deal found 6/9![Frontier logo]()
$265
This Kiwi.com deal was found by Cheapflights users on 6/9. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 7/76:34 pm
STL
- BUF
1 stop18h 19m
Frontier
Tue 7/1411:29 am
BUF
- STL
1 stop7h 08m
Frontier
Deal found 6/9![Frontier logo]()
$187
This Kiwi.com deal was found by Cheapflights users on 6/5. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 7/146:34 pm
STL
- BUF
1 stop18h 19m
Frontier
Fri 7/242:48 pm
BUF
- STL
1 stop19h 09m
Frontier
Deal found 6/5![Frontier logo]()
$188
This Kiwi.com deal was found by Cheapflights users on 6/8. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 7/156:07 pm
MCI
- BUF
1 stop15h 22m
Frontier
Fri 7/172:48 pm
BUF
- MCI
1 stop27h 22m
Frontier
Deal found 6/8![Frontier logo]()
$191
This Kiwi.com deal was found by Cheapflights users on 6/8. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 7/204:57 pm
STL
- BUF
1 stop16h 32m
Frontier
Thu 7/2311:29 am
BUF
- STL
1 stop7h 08m
Frontier
Deal found 6/8![Frontier logo]()
$211
This Kiwi.com deal was found by Cheapflights users on 6/5. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 7/204:57 pm
STL
- BUF
1 stop16h 32m
Frontier
Wed 7/222:48 pm
BUF
- STL
1 stop27h 49m
Frontier
Deal found 6/5![Frontier logo]()
$215
This Kiwi.com deal was found by Cheapflights users on 6/9. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 7/204:57 pm
STL
- BUF
1 stop16h 32m
Frontier
Mon 7/272:48 pm
BUF
- STL
1 stop27h 49m
Frontier
Deal found 6/9![Frontier logo]()
$228
This Kiwi.com deal was found by Cheapflights users on 6/5. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 7/244:57 pm
STL
- BUF
1 stop17h 36m
Frontier
Mon 7/272:48 pm
BUF
- STL
1 stop27h 49m
Frontier
Deal found 6/5![Frontier logo]()
$225
This Kiwi.com deal was found by Cheapflights users on 6/9. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 7/256:07 pm
MCI
- BUF
1 stop15h 22m
Frontier
Sat 8/112:28 pm
BUF
- MCI
1 stop5h 42m
Frontier
Deal found 6/9![Frontier logo]()
$209
One-way flights from Missouri to BuffaloSearch for one-way flight options from Missouri to Buffalo. Find affordable one-way fares based on user searches. Data last updated June 10, 2026.
Search for one-way flight options from Missouri to Buffalo. Find affordable one-way fares based on user searches. Data last updated June 10, 2026.
This Kiwi.com deal was found by Cheapflights users on 6/7. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 8/246:19 pm
MCI
- BUF
1 stop15h 21m
Frontier
Deal found 6/7![Frontier logo]()
$94
This Kiwi.com deal was found by Cheapflights users on 6/7. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 7/76:34 pm
STL
- BUF
1 stop18h 19m
Frontier
Deal found 6/7![Frontier logo]()
$97
This Kiwi.com deal was found by Cheapflights users on 6/9. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 7/226:07 pm
MCI
- BUF
1 stop15h 22m
Frontier
Deal found 6/9![Frontier logo]()
$97
This Kiwi.com deal was found by Cheapflights users on 6/9. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 7/256:07 pm
MCI
- BUF
1 stop15h 22m
Frontier
Deal found 6/9![Frontier logo]()
$99
This Kiwi.com deal was found by Cheapflights users on 6/9. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 8/215:33 pm
STL
- BUF
1 stop17h 01m
Frontier
Deal found 6/9![Frontier logo]()
$104
This Kiwi.com deal was found by Cheapflights users on 6/7. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 7/174:57 pm
STL
- BUF
1 stop17h 36m
Frontier
Deal found 6/7![Frontier logo]()
$106
This Kiwi.com deal was found by Cheapflights users on 6/9. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 9/1710:35 am
STL
- BUF
1 stop24h 46m
Frontier
Deal found 6/9![Frontier logo]()
$119
This Kiwi.com deal was found by Cheapflights users on 6/9. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 6/296:16 pm
MCI
- BUF
1 stop15h 39m
Frontier
Deal found 6/9![Frontier logo]()
$133
This Trip.com deal was found by Cheapflights users on 6/9. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Trip.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 9/1110:35 am
STL
- BUF
1 stop24h 46m
Frontier
Deal found 6/9![Frontier logo]()
$134
This Delta deal was found by Cheapflights users on 6/5. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 7/216:09 pm
STL
- BUF
1 stop4h 49m
Delta
Deal found 6/5![Delta logo]()
$138
This United Airlines deal was found by Cheapflights users on 6/8. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 7/145:45 pm
MCI
- BUF
1 stop5h 14m
United Airlines
Deal found 6/8![United Airlines logo]()
$138
This Southwest deal was found by Cheapflights users on 6/9. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 9/1712:30 pm
STL
- BUF
2 stops9h 10m
Southwest
Deal found 6/9![Southwest logo]()
$157
Find flight deals from Missouri to Buffalo
Keep the following information in mind while searching for Missouri to Buffalo flight deals. Data was last updated June 10, 2026.
Most accurate provider | FlightHub 3 stars |
|---|---|
Most trusted provider | FlightHub 3 stars |
Round-trip from | $186 (Kiwi.com) |
One-way from | $94 (Kiwi.com) |
Popular in | April |
Cheapest in | January |
Average price | $416 |
Cheapflights Fare Finder
Customize your flight search to find flights from Missouri to Buffalo that fit within your specific budget. Explore options based on user searches and filter the results based on your desired price range. Find flights that match your budget for a cost-effective journey. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated June 10, 2026.
Use the filters below to find and compare flights from Missouri to Buffalo that are best for you.
Fly from
Fly to
Route
Depart
Return
Cheapest round-trip
St. LouisBuffalo
STL - BUF
STLBUF
Lambert-St Louis
Sat 10/3
6:30 am-2:10 pm
1 stop6h 40m
Buffalo
Tue 10/6
7:30 am-1:50 pm
2 stops7h 20m
$251
Kansas CityBuffalo
MCI - BUF
MCIBUF
Kansas City
Mon 7/6
6:07 pm-10:29 am
1 stop15h 22m
Buffalo
Sat 7/11
12:28 pm-5:10 pm
1 stop5h 42m
$265
Quickest round-trip
St. LouisBuffalo
STL - BUF
STLBUF
Lambert-St Louis
Tue 9/29
6:40 am-11:17 am
1 stop3h 37m
Buffalo
Tue 10/13
12:50 pm-4:50 pm
1 stop5h 00m
$275
St. LouisBuffalo
STL - BUF
STLBUF
Lambert-St Louis
Wed 9/30
6:00 am-2:23 pm
2 stops7h 23m
Buffalo
Tue 10/13
5:45 pm-9:21 pm
1 stop4h 36m
$280
Kansas CityBuffalo
MCI - BUF
MCIBUF
Kansas City
Tue 9/15
6:30 am-2:20 pm
1 stop6h 50m
Buffalo
Wed 9/16
3:00 pm-8:10 pm
1 stop6h 10m
$315
Kansas CityBuffalo
MCI - BUF
MCIBUF
Kansas City
Thu 7/9
6:05 pm-12:15 am
1 stop5h 10m
Buffalo
Thu 7/16
7:55 pm-11:20 pm
1 stop4h 25m
$315
St. LouisBuffalo
STL - BUF
STLBUF
Lambert-St Louis
Sat 10/3
6:00 am-2:10 pm
2 stops7h 10m
Buffalo
Mon 10/5
4:00 pm-10:35 pm
2 stops7h 35m
$320
St. LouisBuffalo
STL - BUF
STLBUF
Lambert-St Louis
Fri 6/26
5:06 pm-11:34 am
1 stop17h 28m
Buffalo
Tue 6/30
9:02 pm-6:18 pm
2 stops22h 16m
$338
St. LouisBuffalo
STL - BUF
STLBUF
Lambert-St Louis
Tue 9/1
12:59 pm-9:07 pm
1 stop7h 08m
Buffalo
Wed 9/2
10:30 am-3:38 pm
1 stop6h 08m
$342
Kansas CityBuffalo
MCI - BUF
MCIBUF
Kansas City
Wed 7/29
5:40 pm-11:58 pm
1 stop5h 18m
Buffalo
Tue 8/4
7:52 pm-11:27 pm
1 stop4h 35m
$357
Showing 1-10 of 60 resultsSorted by cheapest first
Best time to book a flight from Missouri to Buffalo
Have a flexible travel schedule? Discover the best time to fly to Buffalo from Missouri with our price prediction graph.
MCI-BUF
STL-BUF
SGF-BUF
COU-BUF
Estimated round-trip price
Rates are based on past data. Find the cheapest month and day to book your flight based on your travel requirements, then search for cheap deals.
Cheapflights Insights
Everything you need to know about your flight from Missouri to Buffalo
USMO-BUF
MCI-BUF
STL-BUF
SGF-BUF
COU-BUF
What is the cheapest month to book a flight from Missouri to Buffalo?
Currently, May is the cheapest month in which you can book a flight from Missouri to Buffalo (average of $115). Flying from Missouri to Buffalo in March is currently the most expensive (average of $366). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.
How much does it cost to fly round-trip from Missouri to Buffalo?
Related info for your journey
Find useful and relevant information for your journey from Missouri to Buffalo. Access travel guides, tips, and recommendations to enhance your travel experience. Get information about local attractions, weather, transportation options, and more.
Traveling to a place near Buffalo?
Book flights to Buffalo if you plan to visit one of these locationsLockport
Cheektowaga
Amherst
Batavia
Williamsville
Orchard Park
Eden
Browse thousands of different options on Cheapflights for your next trip
Toggle through the tabs below to find thousands of options on Cheapflights for your next trip.
Alternative routes
Buffalo flight routes
Complete your trip
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Alternative routes for Missouri to Buffalo
See prices for flight routes from nearby airports that may be better suited for you.
Other flights to Buffalo
Explore flights to Buffalo departing from other origins. Flights are based on user searches made on Cheapflights and were last updated on June 10, 2026.
Complete your trip
Complete your trip to Buffalo by adding a car rental and/or hotel reservation to your travel itinerary.
Search flights from Missouri to Buffalo by cabin class
Find flights from Missouri to Buffalo, based on your preferred cabin class, be it economy, premium economy, business, or first class.
Missouri and Buffalo flights
Browse other Missouri and Buffalo flight options. Last updated on June 10, 2026.
Popular flight searches
Check out other popular destinations found by fellow travelers in 2026
Missouri to Buffalo flights
Consider these flights traveling from Missouri to Buffalo.
Top 5 airlines flying from Missouri to Buffalo
Discover the top 5 airlines that operate flights from Missouri to Buffalo. Compare their services, reliability, and customer satisfaction ratings to choose the airline that best suits your travel preferences and needs. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated June 10, 2026.
| Airline | Cheapest | Average | Flexibility | On-time |
|---|---|---|---|---|
| Cheapest$115 | Average$126 | FlexibilityNo cancel fee | On-time62% | |
| Cheapest$233 | Average$320 | FlexibilityNo cancel fee | On-timeN/A | |
| Cheapest$233 | Average$373 | FlexibilityNo cancel fee | On-time71% | |
| Cheapest$274 | Average$422 | FlexibilityNo cancel fee | On-time63% | |
| Cheapest$293 | Average$363 | FlexibilityNo cancel fee | On-time69% |