$84+ Cheap flights from Missouri to Buffalo (BUF)
This is the cheapest one-way flight price found by a Cheapflights user in the last 72 hours by searching for a flight departing on 8/15. Fares are subject to change and may not be available on all flights or dates of travel.
STL — BUF
Aug 28 — Sep 41
Round-trip
1 adult, Economy
We work with more than 300 partners to bring you better travel deals
Find cheap flights from Missouri to Buffalo with Cheapflights
1. Tell us where you want to go
Enter your travel information like dates, passengers, trip type (one-way or round trip), and preferred cabin class then click “Find deals”2. Select your favorite providers
We find the providers serving your travel needs. Choose up to four travel providers to compare side-by-side for flights, hotels, or car rentals.3. Compare prices and book
Review each provider’s pricing and select the best option for you! Book through your favorite provider’s website for a seamless experience.Cheap flight deals from Missouri to Buffalo
Cheapest
Best
Last-minute
One-way
Cheapest flights from Missouri to BuffaloExplore the most affordable flight options available from Missouri to Buffalo. Find the lowest fares from popular airlines and budget airlines, with prices last updated on July 29, 2026.
Explore the most affordable flight options available from Missouri to Buffalo. Find the lowest fares from popular airlines and budget airlines, with prices last updated on July 29, 2026.
This Kiwi.com deal was found by Cheapflights users on 7/26. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 8/206:17 pm
STL
- BUF
1 stop15h 12m
Frontier
Mon 8/2411:36 am
BUF
- STL
1 stop6h 46m
Frontier
Deal found 7/26![Frontier logo]()
$154
This Kiwi.com deal was found by Cheapflights users on 7/27. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 10/2910:35 am
STL
- BUF
1 stop24h 43m
Frontier
Sun 11/11:13 pm
BUF
- STL
1 stop21h 27m
Frontier
Deal found 7/27![Frontier logo]()
$157
This Kiwi.com deal was found by Cheapflights users on 7/26. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 8/154:57 pm
STL
- BUF
1 stop16h 32m
Frontier
Thu 8/2011:36 am
BUF
- STL
1 stop6h 46m
Frontier
Deal found 7/26![Frontier logo]()
$159
This Kiwi.com deal was found by Cheapflights users on 7/28. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 8/174:57 pm
STL
- BUF
1 stop16h 32m
Frontier
Mon 8/2411:36 am
BUF
- STL
1 stop6h 46m
Frontier
Deal found 7/28![Frontier logo]()
$161
This Kiwi.com deal was found by Cheapflights users on 7/28. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 8/206:17 pm
STL
- BUF
1 stop15h 12m
Frontier
Thu 8/277:20 pm
BUF
- STL
1 stop23h 02m
Frontier
Deal found 7/28![Frontier logo]()
$162
This Kiwi.com deal was found by Cheapflights users on 7/27. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 10/1510:35 am
STL
- BUF
1 stop24h 43m
Frontier
Mon 10/191:13 pm
BUF
- STL
1 stop21h 27m
Frontier
Deal found 7/27![Frontier logo]()
$164
This Kiwi.com deal was found by Cheapflights users on 7/28. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 8/174:57 pm
STL
- BUF
1 stop16h 32m
Frontier
Thu 8/277:20 pm
BUF
- STL
1 stop23h 02m
Frontier
Deal found 7/28![Frontier logo]()
$167
This Kiwi.com deal was found by Cheapflights users on 7/24. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 9/36:17 pm
STL
- BUF
1 stop15h 12m
Frontier
Sun 9/611:36 am
BUF
- STL
1 stop6h 46m
Frontier
Deal found 7/24![Frontier logo]()
$172
This Kiwi.com deal was found by Cheapflights users on 7/25. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 10/1910:35 am
STL
- BUF
1 stop24h 43m
Frontier
Thu 10/221:13 pm
BUF
- STL
1 stop21h 27m
Frontier
Deal found 7/25![Frontier logo]()
$173
This Kiwi.com deal was found by Cheapflights users on 7/27. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 8/2411:26 am
MCI
- BUF
1 stop22h 03m
Frontier
Thu 8/277:20 pm
BUF
- MCI
1 stop16h 21m
Frontier
Deal found 7/27![Frontier logo]()
$175
This Kiwi.com deal was found by Cheapflights users on 7/28. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 8/216:17 pm
STL
- BUF
1 stop15h 12m
Frontier
Mon 8/2411:36 am
BUF
- STL
1 stop6h 46m
Frontier
Deal found 7/28![Frontier logo]()
$179
This Kiwi.com deal was found by Cheapflights users on 7/26. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 8/206:17 pm
STL
- BUF
1 stop15h 12m
Frontier
Sun 8/2311:36 am
BUF
- STL
1 stop6h 46m
Frontier
Deal found 7/26![Frontier logo]()
$181
Best flights from Missouri to BuffaloDiscover carefully curated flight deals from Missouri to Buffalo that have cost, travel time, and layovers in mind to ensure you get the best travel experience. Data last updated July 29, 2026.
Discover carefully curated flight deals from Missouri to Buffalo that have cost, travel time, and layovers in mind to ensure you get the best travel experience. Data last updated July 29, 2026.
This Delta deal was found by Cheapflights users on 7/27. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 10/185:32 pm
SGF
- BUF
1 stop5h 27m
Delta
Sat 10/246:00 am
BUF
- SGF
2 stops9h 55m
Delta
Deal found 7/27![Delta logo]()
$300
This Southwest deal was found by Cheapflights users on 7/25. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 9/81:50 pm
STL
- BUF
1 stop7h 00m
Southwest
Tue 9/1512:35 pm
BUF
- STL
1 stop3h 35m
Southwest
Deal found 7/25![Southwest logo]()
$309
This United Airlines deal was found by Cheapflights users on 7/28. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 9/1612:59 pm
STL
- BUF
1 stop7h 08m
United Airlines
Sat 9/195:50 pm
BUF
- STL
1 stop4h 43m
United Airlines
Deal found 7/28![United Airlines logo]()
$309
This Delta deal was found by Cheapflights users on 7/27. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 10/1712:11 pm
SGF
- BUF
2 stops9h 27m
Delta
Thu 10/226:10 am
BUF
- SGF
2 stops9h 30m
Delta
Deal found 7/27![Delta logo]()
$305
This Southwest deal was found by Cheapflights users on 7/24. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 9/2612:45 pm
STL
- BUF
1 stop9h 05m
Southwest
Mon 9/284:35 pm
BUF
- STL
1 stop7h 00m
Southwest
Deal found 7/24![Southwest logo]()
$309
This Southwest deal was found by Cheapflights users on 7/26. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 8/172:25 pm
STL
- BUF
1 stop7h 15m
Southwest
Wed 8/199:45 am
BUF
- STL
1 stop5h 10m
Southwest
Deal found 7/26![Southwest logo]()
$309
This Delta deal was found by Cheapflights users on 7/27. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 10/155:32 pm
SGF
- BUF
1 stop5h 27m
Delta
Fri 10/236:10 am
BUF
- SGF
2 stops9h 30m
Delta
Deal found 7/27![Delta logo]()
$324
This Southwest deal was found by Cheapflights users on 7/28. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 10/305:25 am
STL
- BUF
1 stop4h 00m
Southwest
Mon 11/26:35 pm
BUF
- STL
1 stop6h 30m
Southwest
Deal found 7/28![Southwest logo]()
$311
This United Airlines deal was found by Cheapflights users on 7/26. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 8/316:15 am
COU
- BUF
2 stops7h 03m
United Airlines
Mon 9/76:55 am
BUF
- COU
1 stop4h 21m
United Airlines
Deal found 7/26![United Airlines logo]()
$378
This Southwest deal was found by Cheapflights users on 7/28. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 8/251:50 pm
STL
- BUF
1 stop6h 55m
Southwest
Tue 9/112:00 pm
BUF
- STL
2 stops6h 55m
Southwest
Deal found 7/28![Southwest logo]()
$314
This United Airlines deal was found by Cheapflights users on 7/26. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 8/296:15 am
COU
- BUF
1 stop6h 01m
United Airlines
Tue 9/15:58 pm
BUF
- COU
1 stop5h 57m
United Airlines
Deal found 7/26![United Airlines logo]()
$388
This Southwest deal was found by Cheapflights users on 7/27. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 10/155:25 am
STL
- BUF
2 stops5h 35m
Southwest
Mon 10/196:00 am
BUF
- STL
2 stops7h 15m
Southwest
Deal found 7/27![Southwest logo]()
$319
This United Airlines deal was found by Cheapflights users on 7/24. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 12/123:03 pm
SGF
- BUF
1 stop4h 28m
United Airlines
Tue 12/155:50 pm
BUF
- SGF
1 stop4h 33m
United Airlines
Deal found 7/24![United Airlines logo]()
$394
This Southwest deal was found by Cheapflights users on 7/26. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 9/2610:35 am
MCI
- BUF
1 stop4h 05m
Southwest
Sat 10/39:15 am
BUF
- MCI
1 stop6h 35m
Southwest
Deal found 7/26![Southwest logo]()
$320
This United Airlines deal was found by Cheapflights users on 7/28. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 8/211:37 pm
SGF
- BUF
1 stop8h 00m
United Airlines
Fri 8/285:58 pm
BUF
- SGF
1 stop6h 21m
United Airlines
Deal found 7/28![United Airlines logo]()
$399
This Delta deal was found by Cheapflights users on 7/25. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 8/213:20 pm
SGF
- BUF
1 stop7h 39m
Delta
Fri 8/286:05 am
BUF
- SGF
1 stop5h 48m
Delta
Deal found 7/25![Delta logo]()
$449
This Southwest deal was found by Cheapflights users on 7/27. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 10/155:00 am
MCI
- BUF
1 stop5h 00m
Southwest
Mon 10/194:30 pm
BUF
- MCI
1 stop8h 05m
Southwest
Deal found 7/27![Southwest logo]()
$325
This Delta deal was found by Cheapflights users on 7/25. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 8/92:13 pm
MCI
- BUF
1 stop3h 55m
Delta
Sun 8/167:52 pm
BUF
- MCI
1 stop4h 35m
Delta
Deal found 7/25![Delta logo]()
$467
This Southwest deal was found by Cheapflights users on 7/24. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 9/910:20 am
MCI
- BUF
1 stop4h 05m
Southwest
Tue 9/153:00 pm
BUF
- MCI
2 stops8h 15m
Southwest
Deal found 7/24![Southwest logo]()
$330
This United Airlines deal was found by Cheapflights users on 7/26. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 11/311:27 am
MCI
- BUF
2 stops10h 32m
United Airlines
Sun 11/85:58 pm
BUF
- MCI
1 stop4h 53m
United Airlines
Deal found 7/26![United Airlines logo]()
$456
This Southwest deal was found by Cheapflights users on 7/28. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 9/161:20 pm
STL
- BUF
1 stop7h 25m
Southwest
Sat 9/195:45 am
BUF
- STL
2 stops8h 40m
Southwest
Deal found 7/28![Southwest logo]()
$332
This United Airlines deal was found by Cheapflights users on 7/25. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 8/141:43 pm
MCI
- BUF
1 stop7h 54m
United Airlines
Sun 8/166:55 am
BUF
- MCI
1 stop4h 30m
United Airlines
Deal found 7/25![United Airlines logo]()
$467
This Southwest deal was found by Cheapflights users on 7/29. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 8/2611:55 am
MCI
- BUF
2 stops7h 40m
Southwest
Wed 9/28:55 am
BUF
- MCI
2 stops8h 25m
Southwest
Deal found 7/29![Southwest logo]()
$335
This United Airlines deal was found by Cheapflights users on 7/28. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 8/1412:10 pm
MCI
- BUF
1 stop5h 50m
United Airlines
Mon 8/175:58 pm
BUF
- MCI
1 stop4h 46m
United Airlines
Deal found 7/28![United Airlines logo]()
$497
This Southwest deal was found by Cheapflights users on 7/27. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 8/2412:15 pm
MCI
- BUF
2 stops7h 35m
Southwest
Thu 8/273:55 pm
BUF
- MCI
2 stops7h 40m
Southwest
Deal found 7/27![Southwest logo]()
$340
This Southwest deal was found by Cheapflights users on 7/24. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 11/203:20 pm
STL
- BUF
1 stop8h 40m
Southwest
Mon 11/237:20 am
BUF
- STL
1 stop3h 45m
Southwest
Deal found 7/24![Southwest logo]()
$348
This Southwest deal was found by Cheapflights users on 7/25. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 11/196:40 am
STL
- BUF
1 stop4h 30m
Southwest
Sun 11/227:20 am
BUF
- STL
1 stop3h 45m
Southwest
Deal found 7/25![Southwest logo]()
$348
This Southwest deal was found by Cheapflights users on 7/26. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 10/36:35 am
MCI
- BUF
2 stops7h 00m
Southwest
Sat 10/103:40 pm
BUF
- MCI
2 stops7h 15m
Southwest
Deal found 7/26![Southwest logo]()
$365
Last-minute flights from Missouri to BuffaloDiscover last-minute flight deals from Missouri to Buffalo. Data last updated July 29, 2026 and is based on user searches.
Discover last-minute flight deals from Missouri to Buffalo. Data last updated July 29, 2026 and is based on user searches.
This Kiwi.com deal was found by Cheapflights users on 7/26. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 8/154:57 pm
STL
- BUF
1 stop16h 32m
Frontier
Thu 8/2011:36 am
BUF
- STL
1 stop6h 46m
Frontier
Deal found 7/26![Frontier logo]()
$159
This Kiwi.com deal was found by Cheapflights users on 7/28. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 8/174:57 pm
STL
- BUF
1 stop16h 32m
Frontier
Mon 8/2411:36 am
BUF
- STL
1 stop6h 46m
Frontier
Deal found 7/28![Frontier logo]()
$161
This Kiwi.com deal was found by Cheapflights users on 7/28. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 8/174:57 pm
STL
- BUF
1 stop16h 32m
Frontier
Thu 8/277:20 pm
BUF
- STL
1 stop23h 02m
Frontier
Deal found 7/28![Frontier logo]()
$167
This Kiwi.com deal was found by Cheapflights users on 7/28. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 8/174:57 pm
STL
- BUF
1 stop16h 32m
Frontier
Fri 8/2111:36 am
BUF
- STL
1 stop6h 46m
Frontier
Deal found 7/28![Frontier logo]()
$184
This Kiwi.com deal was found by Cheapflights users on 7/28. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 8/174:57 pm
STL
- BUF
1 stop16h 32m
Frontier
Wed 8/266:54 pm
BUF
- STL
2 stops23h 28m
Frontier
Deal found 7/28![Frontier logo]()
$195
This Kiwi.com deal was found by Cheapflights users on 7/26. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 8/206:17 pm
STL
- BUF
1 stop15h 12m
Frontier
Mon 8/2411:36 am
BUF
- STL
1 stop6h 46m
Frontier
Deal found 7/26![Frontier logo]()
$154
This Kiwi.com deal was found by Cheapflights users on 7/28. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 8/206:17 pm
STL
- BUF
1 stop15h 12m
Frontier
Thu 8/277:20 pm
BUF
- STL
1 stop23h 02m
Frontier
Deal found 7/28![Frontier logo]()
$162
This Kiwi.com deal was found by Cheapflights users on 7/26. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 8/206:17 pm
STL
- BUF
1 stop15h 12m
Frontier
Sun 8/2311:36 am
BUF
- STL
1 stop6h 46m
Frontier
Deal found 7/26![Frontier logo]()
$181
This Kiwi.com deal was found by Cheapflights users on 7/28. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 8/206:17 pm
STL
- BUF
1 stop15h 12m
Frontier
Wed 8/266:54 pm
BUF
- STL
2 stops23h 28m
Frontier
Deal found 7/28![Frontier logo]()
$190
This Kiwi.com deal was found by Cheapflights users on 7/28. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 8/216:17 pm
STL
- BUF
1 stop15h 12m
Frontier
Mon 8/2411:36 am
BUF
- STL
1 stop6h 46m
Frontier
Deal found 7/28![Frontier logo]()
$179
This Kiwi.com deal was found by Cheapflights users on 7/29. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 8/2111:26 am
MCI
- BUF
1 stop22h 03m
Frontier
Sat 8/296:54 pm
BUF
- MCI
2 stops40h 47m
Frontier
Deal found 7/29![Frontier logo]()
$230
This Kiwi.com deal was found by Cheapflights users on 7/27. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 8/2411:26 am
MCI
- BUF
1 stop22h 03m
Frontier
Thu 8/277:20 pm
BUF
- MCI
1 stop16h 21m
Frontier
Deal found 7/27![Frontier logo]()
$175
One-way flights from Missouri to BuffaloSearch for one-way flight options from Missouri to Buffalo. Find affordable one-way fares based on user searches. Data last updated July 29, 2026.
Search for one-way flight options from Missouri to Buffalo. Find affordable one-way fares based on user searches. Data last updated July 29, 2026.
This Kiwi.com deal was found by Cheapflights users on 7/24. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 8/154:57 pm
STL
- BUF
1 stop16h 32m
Frontier
Deal found 7/24![Frontier logo]()
$84
This Kiwi.com deal was found by Cheapflights users on 7/27. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 8/286:17 pm
STL
- BUF
1 stop15h 12m
Frontier
Deal found 7/27![Frontier logo]()
$85
This Kiwi.com deal was found by Cheapflights users on 7/26. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 9/211:26 am
MCI
- BUF
1 stop22h 03m
Frontier
Deal found 7/26![Frontier logo]()
$92
This Kiwi.com deal was found by Cheapflights users on 7/25. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 8/216:17 pm
STL
- BUF
1 stop15h 12m
Frontier
Deal found 7/25![Frontier logo]()
$100
This Kiwi.com deal was found by Cheapflights users on 7/26. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 8/144:57 pm
STL
- BUF
1 stop17h 36m
Frontier
Deal found 7/26![Frontier logo]()
$128
This Kiwi.com deal was found by Cheapflights users on 7/26. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 8/116:34 pm
STL
- BUF
1 stop18h 19m
Frontier
Deal found 7/26![Frontier logo]()
$136
This Kiwi.com deal was found by Cheapflights users on 7/27. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 9/46:17 pm
STL
- BUF
1 stop15h 12m
Frontier
Deal found 7/27![Frontier logo]()
$143
This Kiwi.com deal was found by Cheapflights users on 7/26. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 9/182:29 pm
STL
- BUF
1 stop21h 26m
Frontier
Deal found 7/26![Frontier logo]()
$148
This Kiwi.com deal was found by Cheapflights users on 7/28. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 9/1710:20 am
STL
- BUF
2 stops25h 35m
Frontier
Deal found 7/28![Frontier logo]()
$153
This Delta deal was found by Cheapflights users on 7/27. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 8/256:25 pm
STL
- BUF
1 stop4h 33m
Delta
Deal found 7/27![Delta logo]()
$155
This Kiwi.com deal was found by Cheapflights users on 7/27. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 8/146:17 pm
MCI
- BUF
1 stop16h 16m
Frontier
Deal found 7/27![Frontier logo]()
$161
This Southwest deal was found by Cheapflights users on 7/26. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 10/34:10 pm
MCI
- BUF
1 stop4h 30m
Southwest
Deal found 7/26![Southwest logo]()
$163
Find flight deals from Missouri to Buffalo
Keep the following information in mind while searching for Missouri to Buffalo flight deals. Data was last updated July 29, 2026.
Most accurate provider | FlightHub 3 stars |
|---|---|
Most trusted provider | FlightHub 3 stars |
Round-trip from | $154 (Kiwi.com) |
One-way from | $84 (Kiwi.com) |
Popular in | April |
Cheapest in | January |
Average price | $402 |
Cheapflights Fare Finder
Customize your flight search to find flights from Missouri to Buffalo that fit within your specific budget. Explore options based on user searches and filter the results based on your desired price range. Find flights that match your budget for a cost-effective journey. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated July 29, 2026.
Use the filters below to find and compare flights from Missouri to Buffalo that are best for you.
Fly from
Fly to
Route
Depart
Return
Cheapest round-trip
SpringfieldBuffalo
SGF - BUF
SGFBUF
Springfield-Branson
Sun 10/18
5:32 pm-11:59 pm
1 stop5h 27m
Buffalo
Sat 10/24
6:00 am-2:55 pm
2 stops9h 55m
$300
SpringfieldBuffalo
SGF - BUF
SGFBUF
Springfield-Branson
Sat 10/17
12:11 pm-10:38 pm
2 stops9h 27m
Buffalo
Thu 10/22
6:10 am-2:40 pm
2 stops9h 30m
$305
St. LouisBuffalo
STL - BUF
STLBUF
Lambert-St Louis
Tue 9/8
1:50 pm-9:50 pm
1 stop7h 00m
Buffalo
Tue 9/15
12:35 pm-3:10 pm
1 stop3h 35m
$309
St. LouisBuffalo
STL - BUF
STLBUF
Lambert-St Louis
Wed 9/16
12:59 pm-9:07 pm
1 stop7h 08m
Buffalo
Sat 9/19
5:50 pm-9:33 pm
1 stop4h 43m
$309
St. LouisBuffalo
STL - BUF
STLBUF
Lambert-St Louis
Sat 9/26
12:45 pm-10:50 pm
1 stop9h 05m
Buffalo
Mon 9/28
4:35 pm-10:35 pm
1 stop7h 00m
$309
St. LouisBuffalo
STL - BUF
STLBUF
Lambert-St Louis
Mon 8/17
2:25 pm-10:40 pm
1 stop7h 15m
Buffalo
Wed 8/19
9:45 am-1:55 pm
1 stop5h 10m
$309
St. LouisBuffalo
STL - BUF
STLBUF
Lambert-St Louis
Fri 10/30
5:25 am-10:25 am
1 stop4h 00m
Buffalo
Mon 11/2
6:35 pm-12:05 am
1 stop6h 30m
$311
St. LouisBuffalo
STL - BUF
STLBUF
Lambert-St Louis
Tue 8/25
1:50 pm-9:45 pm
1 stop6h 55m
Buffalo
Tue 9/1
12:00 pm-5:55 pm
2 stops6h 55m
$314
St. LouisBuffalo
STL - BUF
STLBUF
Lambert-St Louis
Thu 10/15
5:25 am-12:00 pm
2 stops5h 35m
Buffalo
Mon 10/19
6:00 am-12:15 pm
2 stops7h 15m
$319
Kansas CityBuffalo
MCI - BUF
MCIBUF
Kansas City
Sat 9/26
10:35 am-3:40 pm
1 stop4h 05m
Buffalo
Sat 10/3
9:15 am-2:50 pm
1 stop6h 35m
$320
Showing 1-10 of 52 resultsSorted by cheapest first
Best time to book a flight from Missouri to Buffalo
Have a flexible travel schedule? Discover the best time to fly to Buffalo from Missouri with our price prediction graph.
STL-BUF
MCI-BUF
SGF-BUF
COU-BUF
Estimated round-trip price
Rates are based on past data. Find the cheapest month and day to book your flight based on your travel requirements, then search for cheap deals.
Cheapflights Insights
Everything you need to know about your flight from Missouri to Buffalo
USMO-BUF
STL-BUF
MCI-BUF
SGF-BUF
COU-BUF
What is the cheapest month to book a flight from Missouri to Buffalo?
Currently, February is the cheapest month in which you can book a flight from Missouri to Buffalo (average of $337). Flying from Missouri to Buffalo in October is currently the most expensive (average of $500). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.
How much does it cost to fly round-trip from Missouri to Buffalo?
Airfare is below average for this route at the moment.
Missouri to Buffalo flights typically cost between $308 and $538 in August.The cheapest round-trip price found within the last 5 days was $154 on Frontier (Aug 20-Aug 24).
Related info for your journey
Find useful and relevant information for your journey from Missouri to Buffalo. Access travel guides, tips, and recommendations to enhance your travel experience. Get information about local attractions, weather, transportation options, and more.
Traveling to a place near Buffalo?
Book flights to Buffalo if you plan to visit one of these locationsLockport
Cheektowaga
Amherst
Williamsville
Orchard Park
Eden
Bowmansville
Browse thousands of different options on Cheapflights for your next trip
Toggle through the tabs below to find thousands of options on Cheapflights for your next trip.
Alternative routes
Buffalo flight routes
Complete your trip
Flights by cabin class
Other flight options
Popular flights
Top destinations
Alternative routes for Missouri to Buffalo
See prices for flight routes from nearby airports that may be better suited for you.
Other flights to Buffalo
Explore flights to Buffalo departing from other origins. Flights are based on user searches made on Cheapflights and were last updated on July 29, 2026.
Complete your trip
Complete your trip to Buffalo by adding a car rental and/or hotel reservation to your travel itinerary.
Search flights from Missouri to Buffalo by cabin class
Find flights from Missouri to Buffalo, based on your preferred cabin class, be it economy, premium economy, business, or first class.
Missouri and Buffalo flights
Browse other Missouri and Buffalo flight options. Last updated on July 29, 2026.
Popular flight searches
Check out other popular destinations found by fellow travelers in 2026
Missouri to Buffalo flights
Consider these flights traveling from Missouri to Buffalo.
Top 5 airlines flying from Missouri to Buffalo
Discover the top 5 airlines that operate flights from Missouri to Buffalo. Compare their services, reliability, and customer satisfaction ratings to choose the airline that best suits your travel preferences and needs. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated July 29, 2026.
| Airline | Cheapest | Average | Flexibility | On-time |
|---|---|---|---|---|
| Cheapest$115 | Average$126 | FlexibilityNo cancel fee | On-time62% | |
| Cheapest$221 | Average$398 | FlexibilityNo cancel fee | On-time71% | |
| Cheapest$226 | Average$350 | FlexibilityNo cancel fee | On-timeN/A | |
| Cheapest$274 | Average$422 | FlexibilityNo cancel fee | On-time63% | |
| Cheapest$283 | Average$383 | FlexibilityNo cancel fee | On-time69% |