HomeSearch by dateVacation packagesHotelsFlight dealsCar rentalTravel tips & news
Mississippi

$81+ Cheap flights from Detroit Metropolitan Wayne County Airport (DTW) to Mississippi

This is the cheapest one-way flight price found by a Cheapflights user in the last 72 hours by searching for a flight departing on 9/22. Fares are subject to change and may not be available on all flights or dates of travel.
DTW — JAN
Aug 23 — Aug 301
Sat 8/23
Sat 8/30
1 adult, Economy
We work with more than 300 partners to bring you better travel deals

Find cheap flights from Detroit to Mississippi with Cheapflights

1. Tell us where you want to go

Enter your travel information like dates, passengers, trip type (one-way or round trip), and preferred cabin class then click “Find deals”

2. Select your favorite providers

We find the providers serving your travel needs. Choose up to four travel providers to compare side-by-side for flights, hotels, or car rentals.

3. Compare prices and book

Review each provider’s pricing and select the best option for you! Book through your favorite provider’s website for a seamless experience.

Cheap flight deals from Detroit to Mississippi

Keep the following information in mind while searching for Detroit to Mississippi flight deals. Data was last updated August 18, 2025.

Round-trip from

$176
(FlightHub)

One-way from

$81
(Priceline)

Popular in

June

Cheapest in

May

Average price

$343
From Detroit Metropolitan Wayne County to Mississippi
Search Deals
One-way flight from Detroit Metropolitan Wayne County to Mississippi
Search Deals
Highest demand for flights based on searches. 4% potential increase in price ($21 potential increase over avg. RT price).
Search Deals
Cheapest flight prices on average. 6% potential price decrease ($26 potential savings vs. average RT price).
Search Deals
Average for round-trip flights in August 2025
Search Deals

Find flight deals from Detroit to Mississippi

Cheapest flights from Detroit to Mississippi
Explore the most affordable flight options available from Detroit to Mississippi. Find the lowest fares from popular airlines and budget airlines, with prices last updated on August 18, 2025.

This FlightHub deal was found by Cheapflights users on 8/16. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure FlightHub is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 10/166:00 amDTW - MEM
1 stop14h 23mFrontier
Sun 10/198:10 pmMEM - DTW
1 stop27h 49mFrontier
Deal found 8/16$176
This Southwest deal was found by Cheapflights users on 8/18. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 11/68:25 pmDTW - MEM
1 stop4h 00mSouthwest
Mon 11/102:20 pmMEM - DTW
1 stop7h 00mSouthwest
Deal found 8/18$184
This American Airlines deal was found by Cheapflights users on 8/17. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 9/194:05 pmDTW - MEM
1 stop7h 54mAmerican Airlines
Mon 9/227:00 amMEM - DTW
1 stop7h 15mAmerican Airlines
Deal found 8/17$187
This Kiwi.com deal was found by Cheapflights users on 8/18. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 9/121:36 pmDTW - MEM
1 stop11h 14mMultiple Airlines
Sun 9/148:35 pmMEM - DTW
1 stop11h 09mMultiple Airlines
Deal found 8/18$191
This Kiwi.com deal was found by Cheapflights users on 8/17. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 9/1311:45 amDTW - MEM
1 stop13h 05mMultiple Airlines
Thu 9/188:35 pmMEM - DTW
1 stop11h 09mMultiple Airlines
Deal found 8/17$192
This Kiwi.com deal was found by Cheapflights users on 8/17. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 9/141:36 pmDTW - MEM
1 stop11h 14mMultiple Airlines
Wed 9/177:00 amMEM - DTW
1 stop24h 44mMultiple Airlines
Deal found 8/17$193
This FlightHub deal was found by Cheapflights users on 8/18. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure FlightHub is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 10/199:30 amDTW - MEM
1 stop6h 42mMultiple Airlines
Fri 10/248:10 pmMEM - DTW
1 stop27h 49mMultiple Airlines
Deal found 8/18$195
This FlightHub deal was found by Cheapflights users on 8/18. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure FlightHub is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 10/176:00 amDTW - MEM
1 stop14h 23mMultiple Airlines
Mon 10/207:00 amMEM - DTW
1 stop24h 38mMultiple Airlines
Deal found 8/18$197
This Flightnetwork deal was found by Cheapflights users on 8/18. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Flightnetwork is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 8/2812:55 pmDTW - MEM
1 stop10h 39mSpirit Airlines
Sun 8/314:59 pmMEM - DTW
Nonstop1h 57mSpirit Airlines
Deal found 8/18$199
This FlightHub deal was found by Cheapflights users on 8/16. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure FlightHub is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 8/2811:54 amDTW - MEM
1 stop6h 31mMultiple Airlines
Sun 8/314:59 pmMEM - DTW
Nonstop1h 57mMultiple Airlines
Deal found 8/16$200
This FlightHub deal was found by Cheapflights users on 8/17. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure FlightHub is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 9/146:10 amDTW - MEM
1 stop14h 09mMultiple Airlines
Sun 9/218:35 pmMEM - DTW
1 stop11h 05mMultiple Airlines
Deal found 8/17$201
This Kiwi.com deal was found by Cheapflights users on 8/16. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 9/57:35 pmDTW - MEM
1 stop29h 15mMultiple Airlines
Thu 9/118:35 pmMEM - DTW
1 stop11h 09mMultiple Airlines
Deal found 8/16$202

Cheapflights Fare Finder

 
Customize your flight search to find flights from Detroit to Mississippi that fit within your specific budget. Explore options based on user searches and filter the results based on your desired price range. Find flights that match your budget for a cost-effective journey. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated August 18, 2025.
Use the filters below to find and compare flights from Detroit Metropolitan Wayne County Airport to Mississippi that are best for you.

Fly from

Detroit

Fly to

Mississippi

Route

Depart

Return

Price

DetroitMemphis

DTW - MEM

DTWMEM

Detroit Metropolitan Wayne County

Thu 10/16

6:00 am-7:23 pm

1 stop14h 23m

Memphis

Sun 10/19

8:10 pm-12:59 am

1 stop27h 49m

$176

DetroitMemphis

DTW - MEM

DTWMEM

Detroit Metropolitan Wayne County

Fri 10/24

6:00 am-7:23 pm

1 stop14h 23m

Memphis

Sun 10/26

8:10 pm-12:59 am

1 stop27h 49m

$176

DetroitMemphis

DTW - MEM

DTWMEM

Detroit Metropolitan Wayne County

Fri 10/17

6:00 am-7:23 pm

1 stop14h 23m

Memphis

Sun 10/19

8:10 pm-12:59 am

1 stop27h 49m

$176

DetroitMemphis

DTW - MEM

DTWMEM

Detroit Metropolitan Wayne County

Thu 11/6

8:25 pm-11:25 pm

1 stop4h 00m

Memphis

Mon 11/10

2:20 pm-10:20 pm

1 stop7h 00m

$184

DetroitMemphis

DTW - MEM

DTWMEM

Detroit Metropolitan Wayne County

Sat 10/4

6:07 pm-10:57 pm

1 stop5h 50m

Memphis

Wed 10/8

10:09 am-3:19 pm

1 stop4h 10m

$187

DetroitMemphis

DTW - MEM

DTWMEM

Detroit Metropolitan Wayne County

Mon 9/15

1:36 pm-11:50 pm

1 stop11h 14m

Memphis

Thu 9/18

8:35 pm-8:44 am

1 stop11h 09m

$187

DetroitMemphis

DTW - MEM

DTWMEM

Detroit Metropolitan Wayne County

Fri 10/3

2:28 pm-9:56 pm

1 stop8h 28m

Memphis

Tue 10/7

3:47 pm-10:34 pm

1 stop5h 47m

$187

DetroitMemphis

DTW - MEM

DTWMEM

Detroit Metropolitan Wayne County

Mon 9/15

1:36 pm-11:50 pm

1 stop11h 14m

Memphis

Wed 9/17

7:00 am-8:44 am

1 stop24h 44m

$187

DetroitMemphis

DTW - MEM

DTWMEM

Detroit Metropolitan Wayne County

Thu 9/25

7:21 pm-11:53 pm

1 stop5h 32m

Memphis

Mon 9/29

6:00 am-1:08 pm

1 stop6h 08m

$187

DetroitMemphis

DTW - MEM

DTWMEM

Detroit Metropolitan Wayne County

Thu 9/25

7:21 pm-11:53 pm

1 stop5h 32m

Memphis

Sun 9/28

5:04 am-11:07 am

1 stop5h 03m

$187

Flights are sorted by cheapest round-trip flights first.

Deals found on 8/16

Showing 1-10 of 56 results
1
2
3
...
6

Best time to book a flight from Detroit to Mississippi

Have a flexible travel schedule? Discover the best time to fly to Mississippi from Detroit with our price prediction graph.
Estimated round-trip price
Rates are based on past data. Find the cheapest month and day to book your flight based on your travel requirements, then search for cheap deals.

Cheapflights Insights

Everything you need to know about your flight from Detroit Metropolitan Wayne County Airport to Mississippi

What is the cheapest month to book a flight from Detroit Metropolitan Wayne County Airport to Mississippi?

Currently, January is the cheapest month in which you can book a flight from Detroit Metropolitan Wayne County Airport to Mississippi (average of $371). Flying from Detroit Metropolitan Wayne County Airport to Mississippi in March is currently the most expensive (average of $448). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.

What is the cheapest time of day to fly from DTW to MS?

Find hourly flight availability from Detroit to Mississippi. Discover flight options and departure times throughout the day, allowing you to choose a departure time that suits your schedule. Data last updated August 18, 2025.

When flying from Detroit Metropolitan Wayne County Airport to Mississippi, the time of day you decide to fly out makes little to no difference towards the overall price you’ll pay on tickets.

Reviews of airlines servicing Mississippi

Get insights into the airlines that provide service to Mississippi. Read reviews, discover amenities, and learn about the overall travel experience offered by airlines. Use this information to make informed decisions when choosing an airline for your flight to Mississippi. Reviews last updated August 18, 2025.
Get a feel of what it's like to fly with Delta and American Airlines from Detroit Metropolitan Wayne County Airport to Mississippi by reading reviews from past customers. You can also see how each airline compares in terms of entertainment options, comfort, food, crew/service, and boarding process.
Delta
8.0
Very good
7,981 reviews

Boarding

8.2

Entertainment

7.9

Crew

8.5

Food

7.3

Overall

8.0

Comfort

7.9

Reviews

1 / 20
10.0
Excellent

Kim,May 2025

PIH - SLC

This trip was fine even with delay I had plenty of time to get connection flight!
Delta
8.0
Very good
7,981 reviews
Delta
8.0
Very good
7,981 reviews

Boarding

8.2

Entertainment

7.9

Crew

8.5

Food

7.3

Overall

8.0

Comfort

7.9

Reviews

1 / 20
10.0
Excellent

Kim,May 2025

PIH - SLC

This trip was fine even with delay I had plenty of time to get connection flight!
American Airlines
7.2
Good
10,000 reviews
Delta
8.0
Very good
7,981 reviews

Boarding

8.2

Entertainment

7.9

Crew

8.5

Food

7.3

Overall

8.0

Comfort

7.9

Reviews

1 / 20
10.0
Excellent

Kim,May 2025

PIH - SLC

This trip was fine even with delay I had plenty of time to get connection flight!

Related info for your journey

Find useful and relevant information for your journey from Detroit to Mississippi. Access travel guides, tips, and recommendations to enhance your travel experience. Get information about local attractions, weather, transportation options, and more.

  • What airport do you fly from for flights from Detroit to Mississippi?

    Most people fly from Detroit Metropolitan Wayne County (DTW) if they book a flight from Detroit to Mississippi. Detroit Metropolitan Wayne County is conveniently located just 17.3 mi from Detroit’s city center.

  • How long is the flight from Detroit Metropolitan Wayne County Airport to Mississippi?

    Frontier, Southwest, and American Airlines can get you from Detroit Metropolitan Wayne County Airport to Mississippi in just under 4h. Your travel time can differ by up to 10h 23m. The distance from Detroit Metropolitan Wayne County Airport to Mississippi is about 611 mi. This flight may include one or multiple stops.

  • What are the cheapest airlines to fly from Detroit Metropolitan Wayne County Airport to Mississippi one-way?

    One-way options have recently been found by users for as low as $81 on Frontier. Other airlines that offer cheap prices include American Airlines from $138 and Delta from $194 one-way.

  • What are the most popular routes from Detroit Metropolitan Wayne County Airport to Mississippi?

    While some choose either Detroit Metropolitan Wayne County - Mobile or Detroit Metropolitan Wayne County - Jackson-Evers Intl, Detroit Metropolitan Wayne County - Memphis is the most popular route from Detroit Metropolitan Wayne County Airport to Mississippi.

  • Can I find deals for flights from Detroit to Mississippi that include hotel bookings?

    Yes. In addition to deals on Detroit to Mississippi flights, Cheapflights offers vacation packages that include both flights and hotel.

  • How can I find direct flights from Detroit to Mississippi?

    After entering your origin and destination, apply the non-stop filter on the search result page to find direct flights from Detroit to Mississippi.

  • Can I find deals for business class flights from Detroit to Mississippi?

    Yes. Cheapflights offers flight deals from Detroit to Mississippi by cabin class. In addition to browsing deals, you can also filter by cabin class on the search results page after making a search.

  • What is the cheapest month to book a flight from Detroit Metropolitan Wayne County Airport to Mississippi?

    Currently, January is the cheapest month in which you can book a flight from Detroit Metropolitan Wayne County Airport to Mississippi (average of $371). Flying from Detroit Metropolitan Wayne County Airport to Mississippi in March is currently the most expensive (average of $448). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.

See more FAQs

Browse thousands of different options on Cheapflights for your next trip

Toggle through the tabs below to find thousands of options on Cheapflights for your next trip.

Alternative routes for Detroit to Mississippi

See prices for flight routes from nearby airports that may be better suited for you.
Detroit to Dallas/Fort Worth flights
Detroit to Las Vegas flights
Detroit to Seattle flights
Detroit to Fort Lauderdale flights
Detroit to Orlando flights
Detroit to John F Kennedy Intl flights
Detroit to Miami flights
Detroit to Los Angeles flights
Detroit to Newark flights
Detroit to LaGuardia flights
Detroit to Denver flights
Detroit to Sky Harbor Intl flights
Detroit to Dulles Intl flights
Detroit to Boston flights
Detroit to Austin flights
Detroit to Reagan-National flights
Detroit to San Francisco flights
Detroit to West Palm Beach flights
Detroit to Atlanta flights
Detroit to Fort Myers flights
Detroit to Love Field flights
Detroit to Tampa flights
Detroit to Honolulu flights
Detroit to Nashville flights
Detroit to San Diego flights
Detroit to New Orleans flights
Detroit to Portland flights
Detroit to Memphis flights
Detroit to Baltimore flights
Detroit to George Bush Intcntl flights
Detroit to Salt Lake City flights
Detroit to O'Hare Intl flights
Detroit to Raleigh flights
Detroit to Oklahoma City flights
Detroit to Hobby flights
Detroit to Kansas City flights
Detroit to Santa Ana flights
Detroit to Ontario flights
Detroit to Minneapolis flights
Detroit to Burbank flights
Detroit to Myrtle Beach flights
Detroit to Charlotte flights
Detroit to Philadelphia flights
Detroit to Charleston flights
Detroit to San Antonio flights
Detroit to Kahului flights
Detroit to Savannah flights
Detroit to Hartford flights
Detroit to Norfolk flights
Detroit to San Jose flights

Top 2 airlines flying from Detroit to Mississippi

Discover the top 2 airlines that operate flights from Detroit to Mississippi. Compare their services, reliability, and customer satisfaction ratings to choose the airline that best suits your travel preferences and needs. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated August 18, 2025.
AirlineCheapestAverageFlexibilityOn-time
American AirlinesCheapest$248Average$354FlexibilityNo cancel feeOn-time71%
DeltaCheapest$258Average$409FlexibilityNo cancel feeOn-timeN/A

100% Free

Cheapflights is completely free to use, so you can start saving the moment you arrive.

Book with Flexibility

Our users can plan ahead with confidence and find flights with no change fees

Travel Smart

Millions of people come to us for their flight needs every year. We help make travel planning easy by providing useful insights and data-driven graphs that can inform your decisions.