Mississippi

$152+ Cheap flights from Detroit Metropolitan Wayne County Airport (DTW) to Mississippi

DTW — JAN
Dec 9 — Dec 161
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Cheap flight deals from Detroit to Mississippi

Cheapest flights from Detroit to Mississippi

Tue 12/155:55 am -
1 stop7h 10m
Tue 1/127:20 am -
1 stop5h 36m
Deal found 11/4$325
Fri 12/256:17 am -
1 stop5h 13m
Thu 12/3112:18 pm -
1 stop7h 50m
Deal found 11/4$351
Thu 12/105:46 am -
1 stop5h 38m
Sat 12/126:00 am -
1 stop7h 26m
Deal found 11/7$362
Thu 11/194:29 pm -
2 stops17h 22m
Wed 11/257:45 pm -
1 stop13h 47m
Deal found 11/4$364
Fri 12/256:55 am -
2 stops11h 40m
Thu 12/311:10 pm -
1 stop3h 50m
Deal found 11/4$380
Sat 12/195:15 am -
1 stop5h 35m
Mon 12/285:20 pm -
1 stop6h 35m
Deal found 11/8$383
Sun 11/228:45 am -
1 stop8h 23m
Thu 11/267:00 am -
1 stop8h 04m
Deal found 11/7$399
Wed 12/166:00 am -
1 stop6h 39m
Wed 12/306:24 pm -
1 stop5h 12m
Deal found 11/7$412
Sat 11/217:42 pm -
1 stop5h 19m
Fri 11/275:49 pm -
1 stop5h 48m
Deal found 11/4$416
Wed 12/98:35 am -
1 stop5h 45m
Sat 12/121:55 pm -
1 stop7h 58m
Deal found 11/4$425
Sat 12/59:05 am -
2 stops11h 29m
Wed 12/91:55 pm -
1 stop7h 47m
Deal found 11/4$436
Thu 11/195:20 am -
1 stop4h 59m
Wed 11/256:04 pm -
1 stop5h 53m
Deal found 11/4$439

Find flight deals from Detroit to Mississippi

Most accurate provider

FlightHub
3 stars

Most trusted provider

FlightHub
3 stars

Round-trip from

$325
(American Airlines)

One-way from

$152
(Kiwi.com)

Popular in

June

Cheapest in

December

Average price

$425
Provider with most accurate pricing for Detroit (DTT)-Jackson-Evers Intl flight deals.
Provider most trusted by Cheapflights users for Detroit (DTT)-Jackson-Evers Intl flights.
From Detroit Metropolitan Wayne County to Mississippi
One-way flight from Detroit Metropolitan Wayne County to Mississippi
Highest demand for flights based on searches. 26% potential increase in price ($168 potential increase over avg. RT price).
Cheapest flight prices on average. 9% potential price decrease ($39 potential savings vs. average RT price).
Average for round-trip flights in November 2026

Cheapflights Fare Finder

 
Use the filters below to find and compare flights from Detroit Metropolitan Wayne County Airport to Mississippi that are best for you.

Fly from

Fly to

Route

Depart

Return

Price

Cheapest round-trip

DetroitGulfport

DTW Detroit Metropolitan Wayne County - GPT Gulfport Biloxi Regional

DTWGPT

Detroit Metropolitan Wayne County

Sat 2/20

4:21 pm-7:10 pm

2 stops27h 49m

Gulfport Biloxi Regional

Wed 12/31

12:00 am-1:00 am

Nonstop0h 00m

$177
Quickest round-trip

DetroitGulfport

DTW Detroit Metropolitan Wayne County - GPT Gulfport Biloxi Regional

DTWGPT

Detroit Metropolitan Wayne County

Sat 11/21

4:25 pm-8:43 pm

1 stop5h 18m

Gulfport Biloxi Regional

Wed 12/31

12:00 am-1:00 am

Nonstop0h 00m

$220

DetroitGulfport

DTW Detroit Metropolitan Wayne County - GPT Gulfport Biloxi Regional

DTWGPT

Detroit Metropolitan Wayne County

Thu 12/3

7:50 am-8:51 am

1 stop26h 01m

Gulfport Biloxi Regional

Wed 12/31

12:00 am-1:00 am

Nonstop0h 00m

$250

DetroitGulfport

DTW Detroit Metropolitan Wayne County - GPT Gulfport Biloxi Regional

DTWGPT

Detroit Metropolitan Wayne County

Wed 12/23

6:00 am-7:05 pm

2 stops38h 05m

Gulfport Biloxi Regional

Wed 12/31

12:00 am-1:00 am

Nonstop0h 00m

$251

DetroitJackson

DTW Detroit Metropolitan Wayne County - JAN Jackson-Evers Intl

DTWJAN

Detroit Metropolitan Wayne County

Sun 12/6

1:30 pm-10:10 pm

2 stops9h 40m

Jackson-Evers Intl

Wed 12/31

12:00 am-1:00 am

Nonstop0h 00m

$257

DetroitGulfport

DTW Detroit Metropolitan Wayne County - GPT Gulfport Biloxi Regional

DTWGPT

Detroit Metropolitan Wayne County

Sat 11/21

9:36 pm-8:51 am

3 stops36h 15m

Gulfport Biloxi Regional

Wed 12/31

12:00 am-1:00 am

Nonstop0h 00m

$260

DetroitJackson

DTW Detroit Metropolitan Wayne County - JAN Jackson-Evers Intl

DTWJAN

Detroit Metropolitan Wayne County

Sat 11/21

5:15 am-2:55 pm

2 stops10h 40m

Jackson-Evers Intl

Wed 12/31

12:00 am-1:00 am

Nonstop0h 00m

$285

DetroitGulfport

DTW Detroit Metropolitan Wayne County - GPT Gulfport Biloxi Regional

DTWGPT

Detroit Metropolitan Wayne County

Fri 2/19

6:00 am-1:18 pm

1 stop8h 18m

Gulfport Biloxi Regional

Wed 12/31

12:00 am-1:00 am

Nonstop0h 00m

$299

DetroitGulfport

DTW Detroit Metropolitan Wayne County - GPT Gulfport Biloxi Regional

DTWGPT

Detroit Metropolitan Wayne County

Mon 12/14

8:35 am-4:08 pm

1 stop8h 33m

Gulfport Biloxi Regional

Wed 12/31

12:00 am-1:00 am

Nonstop0h 00m

$299

DetroitJackson

DTW Detroit Metropolitan Wayne County - JAN Jackson-Evers Intl

DTWJAN

Detroit Metropolitan Wayne County

Mon 11/23

1:30 pm-10:10 pm

2 stops9h 40m

Jackson-Evers Intl

Wed 12/31

12:00 am-1:00 am

Nonstop0h 00m

$305

Flights are sorted by cheapest round-trip flights first.

Deals found on 11/5

Showing 1-10 of 36 resultsSorted by cheapest first
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Best time to book a flight from Detroit to Mississippi

Have a flexible travel schedule? Discover the best time to fly to Mississippi from Detroit with our price prediction graph.
Estimated round-trip price

Cheapflights Insights

Everything you need to know about your flight from Detroit Metropolitan Wayne County Airport to Mississippi

What is the cheapest month to book a flight from Detroit Metropolitan Wayne County Airport to Mississippi?

Currently, January is the cheapest month in which you can book a flight from Detroit Metropolitan Wayne County Airport to Mississippi (average of $346). Flying from Detroit Metropolitan Wayne County Airport to Mississippi in September is currently the most expensive (average of $578). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.

Reviews of airlines servicing Mississippi

Get a feel of what it's like to fly with Southwest,Delta, andAmerican Airlines from Detroit Metropolitan Wayne County Airport to Mississippi by reading reviews from past customers. You can also see how each airline compares in terms of entertainment options, comfort, food, crew/service, and boarding process.

Crew

8.6

Comfort

8.0

Food

7.0

Boarding

8.1

Overall

8.0

Entertainment

7.5

Reviews

1 / 20
8.0
Excellent

Patricia,Oct 2026

DAL - TPA

I love flying southwest, Both flights were packed full full - so not room for all carry one and bags had to be checked but still good flights.

Crew

8.6

Comfort

8.0

Food

7.0

Boarding

8.1

Overall

8.0

Entertainment

7.5

Reviews

1 / 20
8.0
Excellent

Patricia,Oct 2026

DAL - TPA

I love flying southwest, Both flights were packed full full - so not room for all carry one and bags had to be checked but still good flights.

Crew

8.6

Comfort

8.0

Food

7.0

Boarding

8.1

Overall

8.0

Entertainment

7.5

Reviews

1 / 20
8.0
Excellent

Patricia,Oct 2026

DAL - TPA

I love flying southwest, Both flights were packed full full - so not room for all carry one and bags had to be checked but still good flights.

Crew

8.6

Comfort

8.0

Food

7.0

Boarding

8.1

Overall

8.0

Entertainment

7.5

Reviews

1 / 20
8.0
Excellent

Patricia,Oct 2026

DAL - TPA

I love flying southwest, Both flights were packed full full - so not room for all carry one and bags had to be checked but still good flights.

Related info for your journey

  • What airport do you fly from for flights from Detroit to Mississippi?

    Most people fly from Detroit Metropolitan Wayne County (DTW) if they book a flight from Detroit to Mississippi. Detroit Metropolitan Wayne County is conveniently located just 17.3 mi from Detroit’s city center.

  • How long is the flight from Detroit Metropolitan Wayne County Airport to Mississippi?

    American Airlines, Delta, and United Airlines can get you from Detroit Metropolitan Wayne County Airport to Mississippi in just under 5h 38m. Your travel time can differ by up to 2h 45m. The distance from Detroit Metropolitan Wayne County Airport to Mississippi is about 777 mi. This flight may include one or multiple stops.

  • What are the most popular routes from Detroit Metropolitan Wayne County Airport to Mississippi?

  • Can I find deals for flights from Detroit to Mississippi that include hotel bookings?

    Yes. In addition to deals on Detroit to Mississippi flights, Cheapflights offers vacation packages that include both flights and hotel.

  • How can I find direct flights from Detroit to Mississippi?

    After entering your origin and destination, apply the non-stop filter on the search result page to find direct flights from Detroit to Mississippi.

  • Can I find deals for business class flights from Detroit to Mississippi?

    Yes. Cheapflights offers flight deals from Detroit to Mississippi by cabin class. In addition to browsing deals, you can also filter by cabin class on the search results page after making a search.

  • What is the cheapest month to book a flight from Detroit Metropolitan Wayne County Airport to Mississippi?

    Currently, January is the cheapest month in which you can book a flight from Detroit Metropolitan Wayne County Airport to Mississippi (average of $346). Flying from Detroit Metropolitan Wayne County Airport to Mississippi in September is currently the most expensive (average of $578). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.

See more FAQs

Browse thousands of different options on Cheapflights for your next trip

Alternative routes for Detroit to Mississippi

Top 3 airlines flying from Detroit to Mississippi

AirlineCheapestAverageFlexibilityOn-time
DeltaCheapest$131Average$389FlexibilityNo cancel feeOn-timeN/A
American AirlinesCheapest$280Average$392FlexibilityNo cancel feeOn-time71%
SouthwestCheapest$326Average$410FlexibilityNo cancel feeOn-time63%

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