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$542+ Cheap flights from Panama City (PTY) to Milan (MIL)

This is the cheapest one-way flight price found by a Cheapflights user in the last 72 hours by searching for a flight departing on 2/23. Fares are subject to change and may not be available on all flights or dates of travel.
PTY — MIL
Mar 15 — Mar 221
Sun 3/15
Sun 3/22
1 adult, Economy
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Cheap flight deals from Panama City to Milan

Cheapest flights from Panama City to Milan
Explore the most affordable flight options available from Panama City to Milan. Find the lowest fares from popular airlines and budget airlines, with prices last updated on February 13, 2026.

This Air France deal was found by Cheapflights users on 2/13. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Air France is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 5/199:55 pm
PTY
-
MXP
1 stop18h 05m
Air France
Tue 6/1611:25 am
MXP
-
PTY
1 stop15h 20m
Air France
Deal found 2/13$680
This Air France deal was found by Cheapflights users on 2/13. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Air France is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 5/199:55 pm
PTY
-
MXP
1 stop18h 05m
Air France
Wed 6/176:35 pm
MXP
-
PTY
1 stop32h 10m
Air France
Deal found 2/13$693
This Turkish Airlines deal was found by Cheapflights users on 2/11. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Turkish Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 4/2210:20 pm
PTY
-
MXP
1 stop36h 25m
Turkish Airlines
Mon 9/216:50 am
MXP
-
PTY
1 stop20h 35m
Turkish Airlines
Deal found 2/11$708
This Air France deal was found by Cheapflights users on 2/13. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Air France is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 5/199:55 pm
PTY
-
LIN
1 stop27h 55m
Air France
Mon 6/156:25 am
LIN
-
PTY
1 stop20h 20m
Air France
Deal found 2/13$713
This Air France deal was found by Cheapflights users on 2/13. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Air France is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 5/189:55 pm
PTY
-
MXP
1 stop27h 20m
Air France
Tue 6/1611:25 am
MXP
-
PTY
1 stop15h 20m
Air France
Deal found 2/13$715
This Air France deal was found by Cheapflights users on 2/13. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Air France is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 5/199:55 pm
PTY
-
LIN
1 stop27h 55m
Air France
Wed 6/178:45 pm
LIN
-
PTY
1 stop30h 00m
Air France
Deal found 2/13$726
This Air France deal was found by Cheapflights users on 2/13. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Air France is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 5/189:55 pm
PTY
-
MXP
1 stop27h 20m
Air France
Wed 6/173:45 pm
MXP
-
PTY
1 stop35h 00m
Air France
Deal found 2/13$728
This Turkish Airlines deal was found by Cheapflights users on 2/10. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Turkish Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 5/1810:20 pm
PTY
-
MXP
1 stop18h 25m
Turkish Airlines
Fri 5/297:45 pm
MXP
-
PTY
1 stop31h 40m
Turkish Airlines
Deal found 2/10$730
This Turkish Airlines deal was found by Cheapflights users on 2/10. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Turkish Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 5/610:20 pm
PTY
-
MXP
1 stop36h 25m
Turkish Airlines
Fri 5/157:45 pm
MXP
-
PTY
2 stops29h 45m
Turkish Airlines
Deal found 2/10$736
This Air Europa deal was found by Cheapflights users on 2/9. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Air Europa is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 4/158:25 pm
PTY
-
MXP
1 stop13h 50m
Air Europa
Wed 4/2911:05 am
MXP
-
PTY
1 stop14h 35m
Air Europa
Deal found 2/9$740
This Air Europa deal was found by Cheapflights users on 2/11. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Air Europa is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 5/148:25 pm
PTY
-
MXP
1 stop13h 50m
Air Europa
Sat 5/3011:05 am
MXP
-
PTY
1 stop14h 35m
Air Europa
Deal found 2/11$741
This Air France deal was found by Cheapflights users on 2/13. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Air France is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 5/189:55 pm
PTY
-
LIN
1 stop27h 55m
Air France
Tue 6/166:25 am
LIN
-
PTY
1 stop20h 20m
Air France
Deal found 2/13$757

Find flight deals from Panama City to Milan

Discover tips and strategies to find the most affordable flight options for your journey from Panama City (PTY) to Milan (MIL). Learn about various techniques such as flexible date searches, comparing prices across and setting up price alerts. Use these methods to find the cheapest flights available for your travel needs. Data last updated February 13, 2026.

Most accurate provider

FlightHub
3 stars

Most trusted provider

FlightHub
3 stars

Round-trip from

$708
(Turkish Airlines)

One-way from

$542
(Mytrip)

Popular in

December

Cheapest in

October

Average price

$788
Provider with most accurate pricing for Panama City Tocumen Intl-Milan (MIL) flight deals.
Search Deals
Provider most trusted by Cheapflights users for Panama City Tocumen Intl-Milan (MIL) flights.
Search Deals
From Panama City Tocumen Intl to Milan (MIL)
Search Deals
One-way flight from Panama City Tocumen Intl to Milan (MIL)
Search Deals
Highest demand for flights based on searches. 4% potential increase in price ($40 potential increase over avg. RT price).
Search Deals
Cheapest flight prices on average. 1% potential price decrease ($14 potential savings vs. average RT price).
Search Deals
Average for round-trip flights in February 2026
Search Deals

Cheapflights Fare Finder

 
Customize your flight search to find flights from Panama City to Milan that fit within your specific budget. Explore options based on user searches and filter the results based on your desired price range. Find flights that match your budget for a cost-effective journey. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated February 13, 2026.
Use the filters below to find and compare flights from Panama City to Milan that are best for you.

Fly from

Panama City

Fly to

Milan

Route

Depart

Return

Price

Panama CityMilan

PTY - LIN

PTYLIN

Panama City Tocumen Intl

Tue 5/19

9:55 pm-8:50 am

1 stop27h 55m

Milan Linate

Mon 6/15

6:25 am-7:45 pm

1 stop20h 20m

$713

Panama CityMilan

PTY - MXP

PTYMXP

Panama City Tocumen Intl

Mon 5/18

10:20 pm-11:45 pm

1 stop18h 25m

Milan Malpensa

Fri 5/29

7:45 pm-8:25 pm

1 stop31h 40m

$730

Panama CityMilan

PTY - MXP

PTYMXP

Panama City Tocumen Intl

Wed 5/6

10:20 pm-5:45 pm

1 stop36h 25m

Milan Malpensa

Fri 5/15

7:45 pm-6:30 pm

2 stops29h 45m

$736

Panama CityMilan

PTY - MXP

PTYMXP

Panama City Tocumen Intl

Thu 5/14

8:25 pm-5:15 pm

1 stop13h 50m

Milan Malpensa

Sat 5/30

11:05 am-6:40 pm

1 stop14h 35m

$741

Panama CityMilan

PTY - LIN

PTYLIN

Panama City Tocumen Intl

Mon 5/18

9:55 pm-8:50 am

1 stop27h 55m

Milan Linate

Mon 6/15

6:25 am-7:45 pm

1 stop20h 20m

$757

Panama CityMilan

PTY - MXP

PTYMXP

Panama City Tocumen Intl

Wed 5/6

8:25 pm-5:15 pm

1 stop13h 50m

Milan Malpensa

Fri 5/15

11:05 am-6:40 pm

1 stop14h 35m

$759

Panama CityMilan

PTY - MXP

PTYMXP

Panama City Tocumen Intl

Mon 5/18

10:20 pm-11:45 pm

1 stop18h 25m

Milan Malpensa

Sun 6/14

7:45 pm-8:25 pm

1 stop31h 40m

$760

Panama CityMilan

PTY - MXP

PTYMXP

Panama City Tocumen Intl

Wed 4/15

8:25 pm-5:15 pm

1 stop13h 50m

Milan Malpensa

Wed 4/29

11:05 am-6:40 pm

1 stop14h 35m

$761

Panama CityMilan

PTY - MXP

PTYMXP

Panama City Tocumen Intl

Sun 5/17

8:05 pm-8:40 am

1 stop29h 35m

Milan Malpensa

Sun 6/14

7:45 pm-8:25 pm

1 stop31h 40m

$766

Panama CityMilan

PTY - MXP

PTYMXP

Panama City Tocumen Intl

Sun 5/3

8:05 pm-1:20 pm

1 stop34h 15m

Milan Malpensa

Wed 5/6

6:50 am-8:25 pm

1 stop20h 35m

$766

Flights are sorted by cheapest round-trip flights first.

Deals found on 2/12

Showing 1-10 of 32 results
1
2
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  • Most accurate provider: When it comes to deals on Panama City-Milan flights, users find the pricing of FlightHub to be most consistent on Cheapflights vs. FlightHub Users can find the same prices on Panama City-Milan flight deals on Cheapflights vs. FlightHub >95% of the time. Price accuracy is based on data collected from Panama City-Milan flight searches over the past month and is updated monthly.
  • Most trusted provider: When it comes to deals on Panama City-Milan flights, Cheapflights users trust FlightHub the most. FlightHub has received a user feedback score of 3 out of 3 stars (3 being the best), meaning they have been trusted the most by Cheapflights users looking for Panama City-Milan flight deals. Provider user feedback score is based on Cheapflights searches over the past month and is updated monthly.

Best time to book a flight from Panama City to Milan

Have a flexible travel schedule? Discover the best time to fly to Milan from Panama City with our price prediction graph.
Estimated round-trip price
Rates are based on past data. Find the cheapest month and day to book your flight based on your travel requirements, then search for cheap deals.

Cheapflights Insights

Everything you need to know about your flight from Panama City to Milan

How far ahead should I book a flight from Panama City to Milan?

Use this chart to determine the optimal time to book a round-trip flight from Panama City to Milan. Price data was last updated on February 6, 2026.

The price you pay for your flight from Panama City to Milan may vary depending on when you book. For the best chance of a lower fare, look to book 33 days in advance of your trip. Fares are likely to increase a fortnight or so before your departure date.

What is the cheapest month to book a flight from Panama City to Milan?

Currently, June is the cheapest month in which you can book a flight from Panama City to Milan (average of $383). Flying from Panama City to Milan in January is currently the most expensive (average of $869). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.

How much does it cost to fly round-trip from Panama City to Milan?

What’s the top layover airport for flights from Panama City to Milan?

Share of 1-stop round-trip flights from Panama City to Milan chosen by Cheapflights users in the past 12 months, using the same layover each way.

Frankfurt am Main (FRA) – chosen by Cheapflights users on 80% of 1-stop itineraries from Panama City to Milan on Cheapflights.

What’s the cheapest layover airport for flights from Panama City to Milan?

Average round-trip fare for 1-stop flights from Panama City to Milan, chosen by Cheapflights users in the past 12 months, with the same layover each way.

Frankfurt am Main (FRA) is the most affordable 1-stop option, with an average round-trip price of $921.

What’s the fastest layover option from Panama City to Milan?

Shortest average travel time for 1-stop one-way flights from Panama City to Milan, based on itineraries clicked by Cheapflights users over the past 12 months, grouped by layover airport.

Flights via Istanbul (IST) have the shortest average one-way travel time for 1-stop routes: 16h 55m.

Which airport typically offers the quickest layover for flights from Panama City to Milan?

Average layover duration for 1-stop one-way flights from Panama City to Milan, chosen by Cheapflights users in the last 12 months, grouped by stopover airport.

Flights via Istanbul (IST) offer the fastest connection on this route, with an average layover time of 1h 33m.

Reviews of airlines servicing Milan

Get insights into the airlines that provide service to Milan. Read reviews, discover amenities, and learn about the overall travel experience offered by airlines. Use this information to make informed decisions when choosing an airline for your flight to Milan. Reviews last updated February 13, 2026.
Peruse reviews from past customers who have flown with Air France, Turkish Airlines, and Air Europa from Panama City to Milan to help guide your decision. You can also see how each airline stacks up in terms of entertainment options, comfort, food, crew/service, and boarding process.
Air France
7.4
Good
1,534 reviews

Boarding

7.4

Comfort

7.3

Crew

8.1

Overall

7.4

Entertainment

7.0

Food

7.0

Reviews

1 / 20
6.0
Good

Jayesh,Jan 2026

CDG - NMI

Entertainment needs more good Bollywood movies - as this flight was going to Mumbai, India. The Aircraft was a OLD - Is service to India cannot be improved ? The aircraft from Newark to Paris was great n new aircraft BUT aircraft from Paris to Mumbai was very old and poor class
Air France
7.4
Good
1,534 reviews
Air France
7.4
Good
1,534 reviews

Boarding

7.4

Comfort

7.3

Crew

8.1

Overall

7.4

Entertainment

7.0

Food

7.0

Reviews

1 / 20
6.0
Good

Jayesh,Jan 2026

CDG - NMI

Entertainment needs more good Bollywood movies - as this flight was going to Mumbai, India. The Aircraft was a OLD - Is service to India cannot be improved ? The aircraft from Newark to Paris was great n new aircraft BUT aircraft from Paris to Mumbai was very old and poor class
Turkish Airlines
7.3
Good
4,213 reviews
Air France
7.4
Good
1,534 reviews

Boarding

7.4

Comfort

7.3

Crew

8.1

Overall

7.4

Entertainment

7.0

Food

7.0

Reviews

1 / 20
6.0
Good

Jayesh,Jan 2026

CDG - NMI

Entertainment needs more good Bollywood movies - as this flight was going to Mumbai, India. The Aircraft was a OLD - Is service to India cannot be improved ? The aircraft from Newark to Paris was great n new aircraft BUT aircraft from Paris to Mumbai was very old and poor class
Air Europa
6.9
Okay
588 reviews
Air France
7.4
Good
1,534 reviews

Boarding

7.4

Comfort

7.3

Crew

8.1

Overall

7.4

Entertainment

7.0

Food

7.0

Reviews

1 / 20
6.0
Good

Jayesh,Jan 2026

CDG - NMI

Entertainment needs more good Bollywood movies - as this flight was going to Mumbai, India. The Aircraft was a OLD - Is service to India cannot be improved ? The aircraft from Newark to Paris was great n new aircraft BUT aircraft from Paris to Mumbai was very old and poor class
Condor
6.4
Okay
400 reviews
Air France
7.4
Good
1,534 reviews

Boarding

7.4

Comfort

7.3

Crew

8.1

Overall

7.4

Entertainment

7.0

Food

7.0

Reviews

1 / 20
6.0
Good

Jayesh,Jan 2026

CDG - NMI

Entertainment needs more good Bollywood movies - as this flight was going to Mumbai, India. The Aircraft was a OLD - Is service to India cannot be improved ? The aircraft from Newark to Paris was great n new aircraft BUT aircraft from Paris to Mumbai was very old and poor class

Related info for your journey

Find useful and relevant information for your journey from Panama City to Milan. Access travel guides, tips, and recommendations to enhance your travel experience. Get information about local attractions, weather, transportation options, and more.

  • What airport do you fly from for flights from Panama City to Milan?

    Panama City Tocumen Intl (PTY) is the airport you will fly out of if you book a flight from Panama City to Milan. You should not have trouble finding flights to Milan from Tocumen Intl; the airport handles an average of 0 outbound flights to Milan per day. You should also have plenty of airline options to choose from since 3 airlines have flights from the Panama City airport to Milan. It is only a 11.4 mi journey to Tocumen Intl (PTY) from Panama City’s city center.

  • How long is the flight from Panama City to Milan?

    Airlines like Turkish Airlines, Air Europa, and Iberia fly from Panama City to Milan in about 13h 45m. The time it takes to get you to your destination can typically vary by up to 4h 40m. There are 5704 mi between Panama City and Milan. This flight may include one or multiple stops.

  • What are the cheapest airlines flying from Panama City to Milan round-trip?

    Cheapflights users have booked flights from Panama City to Milan round-trip from $678. Other airlines that can offer you cheap pricing are Air France, from $705, and Air Europa, from $742. These flights start at 16% lower than the current average price 3 months from now.

  • Can I find deals for flights from Panama City to Milan that include hotel bookings?

    Yes. In addition to deals on Panama City to Milan flights, Cheapflights offers vacation packages that include both flights and hotel.

  • How can I find direct flights from Panama City to Milan?

    After entering your origin and destination, apply the non-stop filter on the search result page to find direct flights from Panama City to Milan.

  • Can I find deals for business class flights from Panama City to Milan?

    Yes. Cheapflights offers flight deals from Panama City to Milan by cabin class. In addition to browsing deals, you can also filter by cabin class on the search results page after making a search.

  • What is the cheapest month to book a flight from Panama City to Milan?

    Currently, June is the cheapest month in which you can book a flight from Panama City to Milan (average of $383). Flying from Panama City to Milan in January is currently the most expensive (average of $869). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.

See more FAQs

Traveling to a place near Milan?

Book flights to Milan if you plan to visit one of these locations
Monza
Menaggio
Rho
Porlezza
Brescia
Novara
Assago
Bellagio
Stresa
Domodossola

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Top 3 airlines flying from Panama City to Milan

Discover the top 3 airlines that operate flights from Panama City to Milan. Compare their services, reliability, and customer satisfaction ratings to choose the airline that best suits your travel preferences and needs. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated February 13, 2026.
AirlineCheapestAverageFlexibilityOn-time
Turkish AirlinesCheapest$678Average$969FlexibilityNo cancel feeOn-time77%
Air FranceCheapest$705Average$880FlexibilityNo cancel feeOn-time77%
Air EuropaCheapest$742Average$1,331FlexibilityNo cancel feeOn-time83%

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