HomeSearch by dateVacation packagesHotelsFlight dealsCar rentalTravel tips & news
Mexico City

$298+ Cheap flights from Santiago (SCL) to Mexico City (MEX)

This is the cheapest one-way flight price found by a Cheapflights user in the last 72 hours by searching for a flight departing on 11/15. Fares are subject to change and may not be available on all flights or dates of travel.
SCL — MEX
oct. 16 — oct. 231
jue. 10/16
jue. 10/23
1 adult, Economy
We work with more than 300 partners to bring you better travel deals

Find cheap flights from Santiago to Mexico City with Cheapflights

1. Tell us where you want to go

Enter your travel information like dates, passengers, trip type (one-way or round trip), and preferred cabin class then click “Find deals”

2. Select your favorite providers

We find the providers serving your travel needs. Choose up to four travel providers to compare side-by-side for flights, hotels, or car rentals.

3. Compare prices and book

Review each provider’s pricing and select the best option for you! Book through your favorite provider’s website for a seamless experience.

Cheapflights Tip: The best prices from Santiago Arturo Merino Benitez to Mexico City Benito Juarez are usually found in March or May, booked 83 days in advance, depart on a Thursday or Tuesday and return on a Thursday

Cheap flight deals from Santiago to Mexico City

Discover tips and strategies to find the most affordable flight options for your journey from Santiago (SCL) to Mexico City (MEX). Learn about various techniques such as flexible date searches, comparing prices across and setting up price alerts. Use these methods to find the cheapest flights available for your travel needs. Data last updated septiembre 16, 2025.

Round-trip from

$509
(Copa Airlines)

One-way from

$298
(Kiwi.com)

Popular in

January

Cheapest in

March

Average price

$617

Good round-trip deal

$417 or less

Good one-way deal

$660 or less
From Santiago Arturo Merino Benitez to Mexico City Benito Juarez
Search Deals
One-way flight from Santiago Arturo Merino Benitez to Mexico City Benito Juarez
Search Deals
Highest demand for flights based on searches. 8% potential increase in price ($55 potential increase over avg. RT price).
Search Deals
Cheapest flight prices on average. 1% potential price decrease ($10 potential savings vs. average RT price).
Search Deals
Average for round-trip flights in September 2025
Search Deals
Price to beat on a round-trip flight from Santiago Arturo Merino Benitez to Mexico City Benito Juarez.
Search Deals
Price to beat on a one-way flight from Santiago Arturo Merino Benitez to Mexico City Benito Juarez.
Search Deals

Find flight deals from Santiago to Mexico City

Cheapest flights from Santiago to Mexico City
Explore the most affordable flight options available from Santiago to Mexico City. Find the lowest fares from popular airlines and budget airlines, with prices last updated on septiembre 16, 2025.

This Copa Airlines deal was found by Cheapflights users on 9/16. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Copa Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
mié. 12/245:12 amSCL - MEX
1 stop12h 18mCopa Airlines
vie. 1/165:55 amMEX - SCL
1 stop18h 22mCopa Airlines
Deal found 9/16$509
This FlightHub deal was found by Cheapflights users on 9/14. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure FlightHub is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
mar. 12/29:15 amSCL - MEX
Nonstop8h 40mLATAM Airlines
mar. 12/94:00 pmMEX - SCL
1 stop11h 25mLATAM Airlines
Deal found 9/14$516
This Cheapflightsfares deal was found by Cheapflights users on 9/14. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Cheapflightsfares is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
mar. 10/73:30 pmSCL - MEX
1 stop14h 35mAvianca
dom. 10/1212:40 amMEX - SCL
1 stop19h 50mAvianca
Deal found 9/14$518
This LATAM Airlines deal was found by Cheapflights users on 9/16. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure LATAM Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
mar. 10/79:40 amSCL - MEX
Nonstop8h 55mLATAM Airlines
mié. 10/158:00 pmMEX - SCL
Nonstop8h 50mLATAM Airlines
Deal found 9/16$520
This FlightHub deal was found by Cheapflights users on 9/14. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure FlightHub is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
mar. 11/49:15 amSCL - MEX
Nonstop8h 40mLATAM Airlines
mar. 11/117:50 pmMEX - SCL
Nonstop8h 05mLATAM Airlines
Deal found 9/14$522
This Copa Airlines deal was found by Cheapflights users on 9/14. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Copa Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
lun. 11/105:12 amSCL - MEX
1 stop22h 03mCopa Airlines
lun. 11/172:00 amMEX - SCL
1 stop15h 21mCopa Airlines
Deal found 9/14$524
This FlightHub deal was found by Cheapflights users on 9/14. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure FlightHub is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
sáb. 11/154:35 amSCL - MEX
1 stop12h 15mLATAM Airlines
mar. 12/24:00 pmMEX - SCL
1 stop11h 25mLATAM Airlines
Deal found 9/14$528
This Copa Airlines deal was found by Cheapflights users on 9/15. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Copa Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
lun. 12/1512:20 pmSCL - MEX
1 stop15h 40mCopa Airlines
vie. 1/235:55 amMEX - SCL
1 stop19h 19mCopa Airlines
Deal found 9/15$529
This Booking.com deal was found by Cheapflights users on 9/14. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Booking.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
mié. 10/223:30 pmSCL - MEX
1 stop14h 35mMultiple Airlines
mié. 10/297:50 pmMEX - SCL
Nonstop8h 40mMultiple Airlines
Deal found 9/14$542

Cheapflights Fare Finder

 
Customize your flight search to find flights from Santiago to Mexico City that fit within your specific budget. Explore options based on user searches and filter the results based on your desired price range. Find flights that match your budget for a cost-effective journey. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated septiembre 16, 2025.
Use the filters below to find and compare flights from Santiago to Mexico City that are best for you.

Fly from

Santiago

Fly to

Mexico City

Route

Depart

Return

Price

SantiagoMexico City

SCL - MEX

SCLMEX

Santiago Arturo Merino Benitez

vie. 12/26

5:44 am-1:00 am

1 stop22h 16m

Mexico City Benito Juarez

lun. 1/12

1:20 am-11:43 pm

1 stop19h 23m

$509

SantiagoMexico City

SCL - MEX

SCLMEX

Santiago Arturo Merino Benitez

dom. 11/2

1:12 am-7:20 pm

1 stop21h 08m

Mexico City Benito Juarez

mar. 11/18

2:00 am-11:41 pm

1 stop18h 41m

$509

SantiagoMexico City

SCL - MEX

SCLMEX

Santiago Arturo Merino Benitez

jue. 12/18

5:12 am-1:00 am

1 stop22h 48m

Mexico City Benito Juarez

mié. 3/18

5:55 am-12:34 am

1 stop15h 39m

$509

SantiagoMexico City

SCL - MEX

SCLMEX

Santiago Arturo Merino Benitez

mié. 12/24

5:12 am-2:30 pm

1 stop12h 18m

Mexico City Benito Juarez

vie. 1/9

9:25 am-11:43 pm

1 stop11h 18m

$509

SantiagoMexico City

SCL - MEX

SCLMEX

Santiago Arturo Merino Benitez

vie. 12/26

5:44 am-1:00 am

1 stop22h 16m

Mexico City Benito Juarez

mar. 1/6

5:55 am-6:00 am

1 stop21h 05m

$509

SantiagoMexico City

SCL - MEX

SCLMEX

Santiago Arturo Merino Benitez

lun. 11/24

1:12 am-7:20 pm

1 stop21h 08m

Mexico City Benito Juarez

mié. 11/26

1:20 am-11:41 pm

1 stop19h 21m

$509

SantiagoMexico City

SCL - MEX

SCLMEX

Santiago Arturo Merino Benitez

vie. 12/26

5:44 am-1:00 am

1 stop22h 16m

Mexico City Benito Juarez

vie. 1/9

9:25 am-12:32 am

1 stop12h 07m

$509

SantiagoMexico City

SCL - MEX

SCLMEX

Santiago Arturo Merino Benitez

mié. 12/24

5:44 am-7:20 pm

1 stop16h 36m

Mexico City Benito Juarez

vie. 1/16

9:25 am-12:32 am

1 stop12h 07m

$509

SantiagoMexico City

SCL - MEX

SCLMEX

Santiago Arturo Merino Benitez

mié. 11/5

7:25 am-1:55 am

2 stops21h 30m

$307

SantiagoMexico City

SCL - MEX

SCLMEX

Santiago Arturo Merino Benitez

dom. 11/16

7:25 am-1:55 am

2 stops21h 30m

$307

Flights are sorted by cheapest round-trip flights first.

Deals found on 9/15

Showing 1-10 of 16 results
1
2

Best time to book a flight from Santiago to Mexico City

Have a flexible travel schedule? Discover the best time to fly to Mexico City from Santiago with our price prediction graph.
Estimated round-trip price
Rates are based on past data. Find the cheapest month and day to book your flight based on your travel requirements, then search for cheap deals.

Cheapflights Insights

Everything you need to know about your flight from Santiago to Mexico City

How far ahead should I book a flight from Santiago to Mexico City?

Use this chart to determine the optimal time to book a round-trip flight from Santiago to Mexico City. Price data was last updated on September 12, 2025.

The best time to book flights from Santiago to Mexico City is 83 days before your desired departure date. The cost of your flight will likely increase significantly if you book two weeks in advance of your flight.

What is the cheapest month to book a flight from Santiago to Mexico City?

Currently, May is the cheapest month in which you can book a flight from Santiago to Mexico City (average of $387). Flying from Santiago to Mexico City in December is currently the most expensive (average of $615). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.

What is the cheapest time of day to fly from SCL to MEX?

Find hourly flight availability from Santiago to Mexico City. Discover flight options and departure times throughout the day, allowing you to choose a departure time that suits your schedule. Data last updated septiembre 16, 2025.

One of the essential ways to save on airfare from Santiago to Mexico City is to remain as flexible as possible. Flights that are in the morning tend to be the most expensive. A flight at noon could potentially save you up to 38% on airfare.

How much does it cost to fly round-trip from Santiago to Mexico City?

Reviews of airlines servicing Mexico City

Get insights into the airlines that provide service to Mexico City. Read reviews, discover amenities, and learn about the overall travel experience offered by airlines. Use this information to make informed decisions when choosing an airline for your flight to Mexico City. Reviews last updated septiembre 16, 2025.
Read reviews from past customers who have flown Copa Airlines, LATAM Airlines, and Aeromexico from Santiago to Mexico City. Users can see the overall rating for each airline as well as how each is rated in terms of entertainment options, comfort, food, crew/service, and boarding process.
Copa Airlines
7.6
Good
1,531 reviews

Food

6.8

Comfort

7.4

Entertainment

6.8

Boarding

7.8

Overall

7.6

Crew

8.1

Reviews

1 / 20
4.0
Okay

Juan Pablo,Sep 2025

PTY - VVI

not a good expirience, the plane was packed, the seats wear very unconftrable, coudent conect with the entratainmente service on the plane, the onboarding was in charge of a very angry lady i really had a unplesent trip
Copa Airlines
7.6
Good
1,531 reviews
Copa Airlines
7.6
Good
1,531 reviews

Food

6.8

Comfort

7.4

Entertainment

6.8

Boarding

7.8

Overall

7.6

Crew

8.1

Reviews

1 / 20
4.0
Okay

Juan Pablo,Sep 2025

PTY - VVI

not a good expirience, the plane was packed, the seats wear very unconftrable, coudent conect with the entratainmente service on the plane, the onboarding was in charge of a very angry lady i really had a unplesent trip
LATAM Airlines
7.5
Good
1,847 reviews
Copa Airlines
7.6
Good
1,531 reviews

Food

6.8

Comfort

7.4

Entertainment

6.8

Boarding

7.8

Overall

7.6

Crew

8.1

Reviews

1 / 20
4.0
Okay

Juan Pablo,Sep 2025

PTY - VVI

not a good expirience, the plane was packed, the seats wear very unconftrable, coudent conect with the entratainmente service on the plane, the onboarding was in charge of a very angry lady i really had a unplesent trip
Aeromexico
7.5
Good
1,696 reviews
Copa Airlines
7.6
Good
1,531 reviews

Food

6.8

Comfort

7.4

Entertainment

6.8

Boarding

7.8

Overall

7.6

Crew

8.1

Reviews

1 / 20
4.0
Okay

Juan Pablo,Sep 2025

PTY - VVI

not a good expirience, the plane was packed, the seats wear very unconftrable, coudent conect with the entratainmente service on the plane, the onboarding was in charge of a very angry lady i really had a unplesent trip
Avianca
6.7
Okay
2,435 reviews
Copa Airlines
7.6
Good
1,531 reviews

Food

6.8

Comfort

7.4

Entertainment

6.8

Boarding

7.8

Overall

7.6

Crew

8.1

Reviews

1 / 20
4.0
Okay

Juan Pablo,Sep 2025

PTY - VVI

not a good expirience, the plane was packed, the seats wear very unconftrable, coudent conect with the entratainmente service on the plane, the onboarding was in charge of a very angry lady i really had a unplesent trip

Related info for your journey

Find useful and relevant information for your journey from Santiago to Mexico City. Access travel guides, tips, and recommendations to enhance your travel experience. Get information about local attractions, weather, transportation options, and more.

  • How popular is this Santiago to Mexico City flight route?

    The Santiago Arturo Merino Benitez to Mexico City Benito Juarez flight path was viewed by 7 users in the past month. Keep an eye out for changes in search interest prior to high and low season.

  • How long is the flight from Santiago to Mexico City?

    Departing from Santiago to Mexico City will take you 22h 16m. There are 4096 mi between Santiago and Mexico City.

  • What are the cheapest airlines flying from Santiago to Mexico City round-trip?

    Flying on Copa Airlines is currently your cheapest option to Mexico City, with prices starting at $242. Additional round-trip tickets that might be worth considering are offered by Avianca and Aeromexico, with the lowest prices starting at $323 and $344, respectively. Copa Airlines is 60% cheaper than the average price of flights available within the next 90 days to this destination.

  • What are the cheapest flights from Santiago to Mexico City?

    Looking for the cheapest flight from Santiago to Mexico City? While on average our users pay $849, our data indicates the cheapest price to be $303. The most popular route (Santiago Arturo Merino Benitez - Mexico City Benito Juarez), is priced around $489.

  • Can I find deals for flights from Santiago to Mexico City that include hotel bookings?

    Yes. In addition to deals on Santiago to Mexico City flights, Cheapflights offers vacation packages that include both flights and hotel.

  • How can I find direct flights from Santiago to Mexico City?

    After entering your origin and destination, apply the non-stop filter on the search result page to find direct flights from Santiago to Mexico City.

  • Can I find deals for business class flights from Santiago to Mexico City?

    Yes. Cheapflights offers flight deals from Santiago to Mexico City by cabin class. In addition to browsing deals, you can also filter by cabin class on the search results page after making a search.

  • What is the cheapest month to book a flight from Santiago to Mexico City?

    Currently, May is the cheapest month in which you can book a flight from Santiago to Mexico City (average of $387). Flying from Santiago to Mexico City in December is currently the most expensive (average of $615). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.

See more FAQs

Browse thousands of different options on Cheapflights for your next trip

Toggle through the tabs below to find thousands of options on Cheapflights for your next trip.

Top 4 airlines flying from Santiago to Mexico City

Discover the top 4 airlines that operate flights from Santiago to Mexico City. Compare their services, reliability, and customer satisfaction ratings to choose the airline that best suits your travel preferences and needs. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated septiembre 16, 2025.
AirlineCheapestAverageFlexibilityOn-time
Copa AirlinesCheapest$242Average$578FlexibilityNo cancel feeOn-time70%
AviancaCheapest$323Average$556FlexibilityNo cancel feeOn-time71%
AeromexicoCheapest$344Average$605FlexibilityNo cancel feeOn-timeN/A
LATAM AirlinesCheapest$523Average$719FlexibilityNo cancel feeOn-time81%

100% Free

Cheapflights is completely free to use, so you can start saving the moment you arrive.

Book with Flexibility

Our users can plan ahead with confidence and find flights with no change fees

Travel Smart

Millions of people come to us for their flight needs every year. We help make travel planning easy by providing useful insights and data-driven graphs that can inform your decisions.