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$272+ Cheap flights from Santiago (SCL) to Mexico City (MEX)

This is the cheapest one-way flight price found by a Cheapflights user in the last 72 hours by searching for a flight departing on 10/20. Fares are subject to change and may not be available on all flights or dates of travel.
SCL — MEX
Aug 19 — Aug 261
Tue 8/19
Tue 8/26
1 adult, Economy
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Cheapflights Tip: The best prices from Santiago Arturo Merino Benitez to Mexico City Benito Juarez are usually found in March or May, booked 83 days in advance, depart on a Thursday or Tuesday and return on a Thursday

Cheap flight deals from Santiago to Mexico City

Discover tips and strategies to find the most affordable flight options for your journey from Santiago (SCL) to Mexico City (MEX). Learn about various techniques such as flexible date searches, comparing prices across and setting up price alerts. Use these methods to find the cheapest flights available for your travel needs. Data last updated August 14, 2025.

Round-trip from

$534
(SmartFares)

One-way from

$272
(Kiwi.com)

Popular in

January

Cheapest in

March

Average price

$567

Good round-trip deal

$695 or less

Good one-way deal

$663 or less
From Santiago Arturo Merino Benitez to Mexico City Benito Juarez
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One-way flight from Santiago Arturo Merino Benitez to Mexico City Benito Juarez
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Highest demand for flights based on searches. 9% potential increase in price ($66 potential increase over avg. RT price).
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Cheapest flight prices on average. 1% potential price decrease ($10 potential savings vs. average RT price).
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Average for round-trip flights in August 2025
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Price to beat on a round-trip flight from Santiago Arturo Merino Benitez to Mexico City Benito Juarez.
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Price to beat on a one-way flight from Santiago Arturo Merino Benitez to Mexico City Benito Juarez.
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Find flight deals from Santiago to Mexico City

Cheapest flights from Santiago to Mexico City
Explore the most affordable flight options available from Santiago to Mexico City. Find the lowest fares from popular airlines and budget airlines, with prices last updated on August 14, 2025.

This SmartFares deal was found by Cheapflights users on 8/13. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure SmartFares is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 8/298:20 amSCL - MEX
Nonstop8h 35mLATAM Airlines
Tue 9/27:55 pmMEX - SCL
2 stops38h 25mLATAM Airlines
Deal found 8/13$534
This Cheapflightsfares deal was found by Cheapflights users on 8/14. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Cheapflightsfares is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 11/167:35 amSCL - MEX
1 stop18h 20mAvianca
Mon 12/112:40 amMEX - SCL
1 stop20h 00mAvianca
Deal found 8/14$543
This Cheapflightsfares deal was found by Cheapflights users on 8/14. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Cheapflightsfares is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 8/282:30 pmSCL - MEX
1 stop14h 35mAvianca
Wed 9/312:40 amMEX - SCL
1 stop19h 50mAvianca
Deal found 8/14$544
This Booking.com deal was found by Cheapflights users on 8/14. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Booking.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 10/319:30 amSCL - MEX
1 stop17h 05mLATAM Airlines
Tue 11/47:50 pmMEX - SCL
Nonstop8h 05mLATAM Airlines
Deal found 8/14$550
This Mytrip deal was found by Cheapflights users on 8/13. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Mytrip is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 9/279:40 amSCL - MEX
Nonstop8h 55mLATAM Airlines
Sat 10/49:40 pmMEX - SCL
1 stop20h 30mLATAM Airlines
Deal found 8/13$554
This Trip.com deal was found by Cheapflights users on 8/13. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Trip.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 9/229:15 pmSCL - MEX
2 stops16h 40mMultiple Airlines
Fri 9/264:50 pmMEX - SCL
2 stops18h 55mMultiple Airlines
Deal found 8/13$559
This FlightHub deal was found by Cheapflights users on 8/14. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure FlightHub is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 10/289:15 amSCL - MEX
Nonstop8h 40mLATAM Airlines
Tue 11/45:15 pmMEX - SCL
1 stop25h 44mLATAM Airlines
Deal found 8/14$564
This Priceline deal was found by Cheapflights users on 8/14. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Priceline is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 9/223:30 pmSCL - MEX
1 stop14h 35mAvianca
Thu 9/2512:40 amMEX - SCL
1 stop19h 50mAvianca
Deal found 8/14$568
This Mytrip deal was found by Cheapflights users on 8/14. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Mytrip is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 9/221:45 amSCL - MEX
3 stops24h 35mMultiple Airlines
Fri 9/264:55 amMEX - SCL
1 stop21h 20mMultiple Airlines
Deal found 8/14$571

Cheapflights Fare Finder

 
Customize your flight search to find flights from Santiago to Mexico City that fit within your specific budget. Explore options based on user searches and filter the results based on your desired price range. Find flights that match your budget for a cost-effective journey. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated August 14, 2025.
Use the filters below to find and compare flights from Santiago to Mexico City that are best for you.

Fly from

Santiago

Fly to

Mexico City

Route

Depart

Return

Price

SantiagoMexico City

SCL - MEX

SCLMEX

Santiago Arturo Merino Benitez

Fri 8/29

8:20 am-2:55 pm

Nonstop8h 35m

Mexico City Benito Juarez

Tue 9/2

7:55 pm-12:20 pm

2 stops38h 25m

$534

SantiagoMexico City

SCL - MEX

SCLMEX

Santiago Arturo Merino Benitez

Sun 11/16

4:25 pm-12:10 pm

1 stop22h 45m

Mexico City Benito Juarez

Mon 12/1

12:40 am-11:40 pm

1 stop20h 00m

$543

SantiagoMexico City

SCL - MEX

SCLMEX

Santiago Arturo Merino Benitez

Mon 10/6

12:55 am-12:05 pm

1 stop14h 10m

Mexico City Benito Juarez

Tue 10/14

12:40 am-11:30 pm

1 stop19h 50m

$544

SantiagoMexico City

SCL - MEX

SCLMEX

Santiago Arturo Merino Benitez

Mon 9/22

12:55 am-11:00 pm

1 stop25h 05m

Mexico City Benito Juarez

Fri 9/26

2:00 pm-5:15 am

1 stop12h 15m

$544

SantiagoMexico City

SCL - MEX

SCLMEX

Santiago Arturo Merino Benitez

Mon 12/1

7:25 am-6:10 pm

1 stop13h 45m

Mexico City Benito Juarez

Sat 12/13

1:50 pm-5:35 am

1 stop12h 45m

$544

SantiagoMexico City

SCL - MEX

SCLMEX

Santiago Arturo Merino Benitez

Wed 9/3

11:55 pm-12:05 pm

1 stop14h 10m

Mexico City Benito Juarez

Mon 9/15

2:00 pm-5:15 am

1 stop12h 15m

$544

SantiagoMexico City

SCL - MEX

SCLMEX

Santiago Arturo Merino Benitez

Mon 10/20

3:30 pm-5:45 am

2 stops41h 15m

$272

SantiagoMexico City

SCL - MEX

SCLMEX

Santiago Arturo Merino Benitez

Mon 10/27

1:30 am-5:45 am

3 stops31h 15m

$276

SantiagoMexico City

SCL - MEX

SCLMEX

Santiago Arturo Merino Benitez

Sun 11/9

9:10 pm-11:20 am

2 stops17h 10m

$276

SantiagoMexico City

SCL - MEX

SCLMEX

Santiago Arturo Merino Benitez

Wed 10/29

1:30 am-5:45 am

3 stops31h 15m

$277

Flights are sorted by cheapest round-trip flights first.

Deals found on 8/13

Showing 1-10 of 15 results
1
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Best time to book a flight from Santiago to Mexico City

Have a flexible travel schedule? Discover the best time to fly to Mexico City from Santiago with our price prediction graph.
Estimated round-trip price
Rates are based on past data. Find the cheapest month and day to book your flight based on your travel requirements, then search for cheap deals.

Cheapflights Insights

Everything you need to know about your flight from Santiago to Mexico City

How far ahead should I book a flight from Santiago to Mexico City?

Use this chart to determine the optimal time to book a round-trip flight from Santiago to Mexico City. Price data was last updated on August 8, 2025.

The best time to book flights from Santiago to Mexico City is 83 days before your desired departure date. The cost of your flight will likely increase significantly if you book two weeks in advance of your flight.

What is the cheapest month to book a flight from Santiago to Mexico City?

Currently, May is the cheapest month in which you can book a flight from Santiago to Mexico City (average of $387). Flying from Santiago to Mexico City in December is currently the most expensive (average of $615). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.

What is the cheapest time of day to fly from SCL to MEX?

Find hourly flight availability from Santiago to Mexico City. Discover flight options and departure times throughout the day, allowing you to choose a departure time that suits your schedule. Data last updated August 14, 2025.

One of the essential ways to save on airfare from Santiago to Mexico City is to remain as flexible as possible. Flights that are in the morning tend to be the most expensive. A flight at noon could potentially save you up to 38% on airfare.

How much does it cost to fly round-trip from Santiago to Mexico City?

Reviews of airlines servicing Mexico City

Get insights into the airlines that provide service to Mexico City. Read reviews, discover amenities, and learn about the overall travel experience offered by airlines. Use this information to make informed decisions when choosing an airline for your flight to Mexico City. Reviews last updated August 14, 2025.
Read reviews from past customers who have flown LATAM Airlines, Copa Airlines, and Aeromexico from Santiago to Mexico City. Users can see the overall rating for each airline as well as how each is rated in terms of entertainment options, comfort, food, crew/service, and boarding process.
LATAM Airlines
7.5
Good
1,840 reviews

Boarding

7.6

Entertainment

7.0

Food

6.7

Crew

8.0

Comfort

7.4

Overall

7.5

Reviews

1 / 20
4.0
Okay

Duane,Jun 2025

GRU - MAD

The flight crew were accommodating and friendly. However, it was annoying that I did not receive the seat I had reserved when I originally booked my flight and was not able to get much help before takeoff.
LATAM Airlines
7.5
Good
1,840 reviews
LATAM Airlines
7.5
Good
1,840 reviews

Boarding

7.6

Entertainment

7.0

Food

6.7

Crew

8.0

Comfort

7.4

Overall

7.5

Reviews

1 / 20
4.0
Okay

Duane,Jun 2025

GRU - MAD

The flight crew were accommodating and friendly. However, it was annoying that I did not receive the seat I had reserved when I originally booked my flight and was not able to get much help before takeoff.
Copa Airlines
7.5
Good
1,507 reviews
LATAM Airlines
7.5
Good
1,840 reviews

Boarding

7.6

Entertainment

7.0

Food

6.7

Crew

8.0

Comfort

7.4

Overall

7.5

Reviews

1 / 20
4.0
Okay

Duane,Jun 2025

GRU - MAD

The flight crew were accommodating and friendly. However, it was annoying that I did not receive the seat I had reserved when I originally booked my flight and was not able to get much help before takeoff.
Aeromexico
7.5
Good
1,723 reviews
LATAM Airlines
7.5
Good
1,840 reviews

Boarding

7.6

Entertainment

7.0

Food

6.7

Crew

8.0

Comfort

7.4

Overall

7.5

Reviews

1 / 20
4.0
Okay

Duane,Jun 2025

GRU - MAD

The flight crew were accommodating and friendly. However, it was annoying that I did not receive the seat I had reserved when I originally booked my flight and was not able to get much help before takeoff.
Avianca
6.7
Okay
2,399 reviews
LATAM Airlines
7.5
Good
1,840 reviews

Boarding

7.6

Entertainment

7.0

Food

6.7

Crew

8.0

Comfort

7.4

Overall

7.5

Reviews

1 / 20
4.0
Okay

Duane,Jun 2025

GRU - MAD

The flight crew were accommodating and friendly. However, it was annoying that I did not receive the seat I had reserved when I originally booked my flight and was not able to get much help before takeoff.

Related info for your journey

Find useful and relevant information for your journey from Santiago to Mexico City. Access travel guides, tips, and recommendations to enhance your travel experience. Get information about local attractions, weather, transportation options, and more.

  • How popular is this Santiago to Mexico City flight route?

    The Santiago Arturo Merino Benitez to Mexico City Benito Juarez flight path was viewed by 5 users in the past month. Keep an eye out for changes in search interest prior to high and low season.

  • What are the cheapest airlines flying from Santiago to Mexico City round-trip?

    Flying on Copa Airlines is currently your cheapest option to Mexico City, with prices starting at $242. Additional round-trip tickets that might be worth considering are offered by Avianca and Aeromexico, with the lowest prices starting at $323 and $347, respectively. Copa Airlines is 60% cheaper than the average price of flights available within the next 90 days to this destination.

  • What are the cheapest flights from Santiago to Mexico City?

    Looking for the cheapest flight from Santiago to Mexico City? While on average our users pay $818, our data indicates the cheapest price to be $270. The most popular route (Santiago Arturo Merino Benitez - Mexico City Benito Juarez), is priced around $512.

  • Can I find deals for flights from Santiago to Mexico City that include hotel bookings?

    Yes. In addition to deals on Santiago to Mexico City flights, Cheapflights offers vacation packages that include both flights and hotel.

  • How can I find direct flights from Santiago to Mexico City?

    After entering your origin and destination, apply the non-stop filter on the search result page to find direct flights from Santiago to Mexico City.

  • Can I find deals for business class flights from Santiago to Mexico City?

    Yes. Cheapflights offers flight deals from Santiago to Mexico City by cabin class. In addition to browsing deals, you can also filter by cabin class on the search results page after making a search.

  • What is the cheapest month to book a flight from Santiago to Mexico City?

    Currently, May is the cheapest month in which you can book a flight from Santiago to Mexico City (average of $387). Flying from Santiago to Mexico City in December is currently the most expensive (average of $615). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.

See more FAQs

Browse thousands of different options on Cheapflights for your next trip

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Top 4 airlines flying from Santiago to Mexico City

Discover the top 4 airlines that operate flights from Santiago to Mexico City. Compare their services, reliability, and customer satisfaction ratings to choose the airline that best suits your travel preferences and needs. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated August 14, 2025.
AirlineCheapestAverageFlexibilityOn-time
Copa AirlinesCheapest$242Average$564FlexibilityNo cancel feeOn-time70%
AviancaCheapest$323Average$554FlexibilityNo cancel feeOn-time71%
AeromexicoCheapest$347Average$605FlexibilityNo cancel feeOn-timeN/A
LATAM AirlinesCheapest$492Average$705FlexibilityNo cancel feeOn-time81%

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