
Most accurate provider | FlightHub 3 stars |
|---|---|
Most trusted provider | FlightHub 3 stars |
Round-trip from | $545 (Kiwi.com) |
One-way from | $302 (Copa Airlines) |
Popular in | April |
Cheapest in | November |
Average price | $574 |
Good round-trip deal | $703 or less |
Good one-way deal | $282 or less |
Fly from
Fly to
Route
Depart
Return
SantiagoMexico City
SCL - MEX
SCLMEX
Santiago Arturo Merino Benitez
Sun 5/31
2:22 am-10:05 pm
1 stop21h 43m
Mexico City Benito Juarez
Fri 6/5
1:20 am-10:43 pm
1 stop19h 23m
SantiagoMexico City
SCL - MEX
SCLMEX
Santiago Arturo Merino Benitez
Tue 5/5
2:22 am-12:10 pm
1 stop11h 48m
Mexico City Benito Juarez
Sat 5/16
1:20 am-11:26 pm
1 stop20h 06m
SantiagoMexico City
SCL - MEX
SCLMEX
Santiago Arturo Merino Benitez
Tue 4/28
4:49 am-2:30 pm
1 stop11h 41m
Mexico City Benito Juarez
Fri 5/8
9:50 am-2:20 am
1 stop14h 30m
SantiagoMexico City
SCL - MEX
SCLMEX
Santiago Arturo Merino Benitez
Sat 5/16
11:17 am-12:15 am
1 stop14h 58m
Mexico City Benito Juarez
Mon 5/25
2:10 am-7:23 pm
1 stop15h 13m
SantiagoMexico City
SCL - MEX
SCLMEX
Santiago Arturo Merino Benitez
Tue 4/21
12:09 am-12:10 pm
1 stop14h 01m
Mexico City Benito Juarez
Tue 5/5
1:20 am-7:23 pm
1 stop16h 03m
SantiagoMexico City
SCL - MEX
SCLMEX
Santiago Arturo Merino Benitez
Fri 5/22
11:17 am-10:05 pm
1 stop12h 48m
Mexico City Benito Juarez
Fri 5/29
9:50 am-3:00 am
1 stop15h 10m
SantiagoMexico City
SCL - MEX
SCLMEX
Santiago Arturo Merino Benitez
Tue 4/28
4:17 am-2:30 pm
1 stop12h 13m
Mexico City Benito Juarez
Sat 5/9
2:10 am-10:43 pm
1 stop18h 33m
SantiagoMexico City
SCL - MEX
SCLMEX
Santiago Arturo Merino Benitez
Wed 5/6
2:22 am-7:05 pm
1 stop18h 43m
Mexico City Benito Juarez
Thu 5/28
5:50 am-10:43 pm
1 stop14h 53m
SantiagoMexico City
SCL - MEX
SCLMEX
Santiago Arturo Merino Benitez
Wed 4/15
4:49 am-7:05 pm
1 stop16h 16m
Mexico City Benito Juarez
Tue 5/5
5:50 am-10:43 pm
1 stop14h 53m
SantiagoMexico City
SCL - MEX
SCLMEX
Santiago Arturo Merino Benitez
Fri 5/1
11:17 am-12:15 am
1 stop14h 58m
Mexico City Benito Juarez
Thu 5/14
1:10 pm-3:00 am
1 stop11h 50m
| Provider | Price Accuracy | Trust Score* |
|---|---|---|
| Price Accuracy3 stars | Trust Score*3 stars | |
| Price Accuracy2 stars | Trust Score*3 stars | |
| Price Accuracy2 stars | Trust Score*2 stars |
The best time to book flights from Santiago to Mexico City is 83 days before your desired departure date. The cost of your flight will likely increase significantly if you book two weeks in advance of your flight.
Currently, June is the cheapest month in which you can book a flight from Santiago to Mexico City (average of $314). Flying from Santiago to Mexico City in January is currently the most expensive (average of $475). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.
Regardless of the time of day you decide to fly, the ticket price will remain around the same. Book flights from Santiago to Mexico City as you normally would.
About 14% of weekly flights between Santiago and Mexico City have experienced delays in the past year, with the average delay time being 183 minutes.
Historically, flights departing at night are less likely to be delayed, whereas flights leaving in the morning tend to experience delays more often.
Tuesday tends to have the lowest number of delays on this route, whereas Monday has historically faced a higher average of delays compared to other days of the week.
Over the last year, LATAM Airlines have had the lowest number of delays on this route, with just 7% of flights being delayed.
Boarding
Overall
Comfort
Entertainment
Food
Crew
Reviews
Maria,Dec 2025
PTY - SLA
Boarding
Overall
Comfort
Entertainment
Food
Crew
Reviews
Maria,Dec 2025
PTY - SLA
Boarding
Overall
Comfort
Entertainment
Food
Crew
Reviews
Maria,Dec 2025
PTY - SLA
Boarding
Overall
Comfort
Entertainment
Food
Crew
Reviews
Maria,Dec 2025
PTY - SLA
Boarding
Overall
Comfort
Entertainment
Food
Crew
Reviews
Maria,Dec 2025
PTY - SLA
| Airline | Cheapest | Average | Flexibility | On-time |
|---|---|---|---|---|
| Cheapest$344 | Average$588 | FlexibilityNo cancel fee | On-timeN/A | |
| Cheapest$371 | Average$638 | FlexibilityNo cancel fee | On-time70% | |
| Cheapest$487 | Average$576 | FlexibilityNo cancel fee | On-time71% | |
| Cheapest$508 | Average$713 | FlexibilityNo cancel fee | On-time81% |