How often are flights from Santiago to Mexico City delayed?

About 12% of weekly flights between Santiago and Mexico City have experienced delays in the past year, with the average delay time being 138 minutes.

Which airline has the best punctuality record on Santiago to Mexico City flights?

Over the last year, Aeromexico have had the lowest number of delays on this route, with just 3% of flights being delayed.

What is the most punctual flight time for Santiago to Mexico City flights?

Historically, flights departing at night are less likely to be delayed, whereas flights leaving in the morning tend to experience delays more often.

What day of the week experiences the fewest flight delays on this route?

Tuesday tends to have the lowest number of delays on this route, whereas Thursday has historically faced a higher average of delays compared to other days of the week.

How popular is this Santiago to Mexico City flight route?

The Santiago Arturo Merino Benitez to Mexico City Benito Juarez flight path was viewed by 7 users in the past month. Keep an eye out for changes in search interest prior to high and low season.

How long is the flight from Santiago to Mexico City?

Departing from Santiago to Mexico City will take you 8h 50m. There are 4096 mi between Santiago and Mexico City. When browsing for deals, the options you’ll see will be for both nonstop flights and flights with stops.

What are the cheapest airlines flying from Santiago to Mexico City round-trip?

Flying on Copa Airlines is currently your cheapest option to Mexico City, with prices starting at $256. Additional round-trip tickets that might be worth considering are offered by Aeromexico and Avianca, with the lowest prices starting at $344 and $487, respectively. Copa Airlines is 57% cheaper than the average price of flights available within the next 90 days to this destination.

What are the cheapest airlines to fly from Santiago to Mexico City one-way?

To fly one-way, consider booking your trip with Arajet, which is currently one of the cheapest options available, starting at $180. Avianca flights start at $233 while deals on Copa Airlines start at $241 one-way.

Weekly flight availability from Santiago to Mexico City

The most flights from SCL to MEX are scheduled on a Friday (4 on average). You will have fewer flight options on Tuesday, which is when the least amount of flights are scheduled (1 on average).

In terms of precipitation, rainfall in Mexico City ranges from 0.0 - 4.7 inches per month. July is typically the wettest month, when rainfall can reach 4.7 in. January is typically the driest time to visit Mexico City when rainfall is around 0.0 in.

If weather is an important factor for your trip to Mexico City, use this chart to help with planning. For those seeking warmer temperatures, May is the ideal time of year to visit, when temperatures reach an average of 66.2 F. Travelers looking to avoid the cold should look outside of January, when temperatures are typically at their lowest (around 55.4 F).

What are the cheapest flights from Santiago to Mexico City?

Looking for the cheapest flight from Santiago to Mexico City? While on average our users pay $1,009, our data indicates the cheapest price to be $258. The most popular route (Santiago Arturo Merino Benitez - Mexico City Benito Juarez), is priced around $469.

What are the most reliable airlines from Santiago to Mexico City?

Looking for the most reliable airlines to get you to your destination on time? Our data shows these are most likely to get you from Santiago to Mexico City on time: WestJet (88%), Aeromexico (88%), LATAM Airlines (47%).

What are the most popular airlines that fly from Santiago to Mexico City?

Consider LATAM Airlines, Copa Airlines or Avianca when booking your flight. These represent the most popular airlines when flying from Santiago to Mexico City.

Most accurate provider : When it comes to deals on Santiago-Mexico City flights, users find the pricing of Gotogate to be most consistent on Cheapflights vs. Gotogate Users can find the same prices on Santiago-Mexico City flight deals on Cheapflights vs. Gotogate >95% of the time. Price accuracy is based on data collected from Santiago-Mexico City flight searches over the past month and is updated monthly.

Most trusted provider : When it comes to deals on Santiago-Mexico City flights, Cheapflights users trust Gotogate the most. Gotogate has received a user feedback score of 3 out of 3 stars (3 being the best), meaning they have been trusted the most by Cheapflights users looking for Santiago-Mexico City flight deals. Provider user feedback score is based on Cheapflights searches over the past month and is updated monthly.

What airports do I use to fly from Santiago to Mexico City?

To fly from Santiago to Mexico City, you need to book a flight from Arturo Merino Benitez (SCL) to Benito Juarez (MEX). Nonstop flights to Mexico City Benito Juarez from Santiago Arturo Merino Benitez take 8h 40m on average. When it comes time to book airfare, you have a few options: there are 2 outbound flights from Arturo Merino Benitez to Benito Juarez offered by 4 different airlines.

Can I find deals for flights from Santiago to Mexico City that include hotel bookings?

Yes. In addition to deals on Santiago to Mexico City flights, Cheapflights offers vacation packages that include both flights and hotel.

How can I find direct flights from Santiago to Mexico City?

After entering your origin and destination, apply the non-stop filter on the search result page to find direct flights from Santiago to Mexico City.

Can I find deals for business class flights from Santiago to Mexico City?

Yes. Cheapflights offers flight deals from Santiago to Mexico City by cabin class. In addition to browsing deals, you can also filter by cabin class on the search results page after making a search.

$273+ Flights from Santiago to Mexico City

Q: How much does it cost to fly round-trip from Santiago to Mexico City?

Airfare is typical for this route at the moment. Santiago to Mexico City flights typically cost between $532 and $736 in March. The cheapest round-trip price found within the last 3 days was $555 on Copa Airlines (Mar 10-Mar 24).

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Enter your travel information like dates, passengers, trip type (one-way or round trip), and preferred cabin class then click “Find deals”

2. Select your favorite providers

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Cheapflights Tip: The best prices from Santiago Arturo Merino Benitez to Mexico City Benito Juarez are usually found in March or November, booked 83 days in advance, depart on a Tuesday or Thursday and return on a Thursday

Cheap flight deals from Santiago to Mexico City

Cheapest flights from Santiago to Mexico City
Explore the most affordable flight options available from Santiago to Mexico City. Find the lowest fares from popular airlines and budget airlines, with prices last updated on December 23, 2025.

Wed 12/2412:20 pmSCL - MEX

1 stop12h 45mCopa Airlines

Thu 1/151:10 pmMEX - SCL

1 stop12h 04mCopa Airlines

Deal found 12/22

$528

Tue 12/231:08 amSCL - MEX

1 stop14h 02mCopa Airlines

Fri 1/95:55 amMEX - SCL

1 stop19h 19mCopa Airlines

Deal found 12/22

$628

Mon 12/225:12 amSCL - MEX

1 stop17h 08mCopa Airlines

Tue 1/65:55 amMEX - SCL

1 stop11h 25mCopa Airlines

Deal found 12/21

$644

Wed 12/245:44 amSCL - MEX

1 stop19h 21mCopa Airlines

Thu 1/152:00 amMEX - SCL

1 stop15h 20mCopa Airlines

Deal found 12/21

$648

Fri 12/2612:20 pmSCL - MEX

1 stop12h 45mCopa Airlines

Sun 12/285:55 amMEX - SCL

1 stop14h 46mCopa Airlines

Deal found 12/22

$696

Fri 12/2612:20 pmSCL - MEX

1 stop15h 40mCopa Airlines

Thu 1/153:30 pmMEX - SCL

1 stop11h 30mCopa Airlines

Deal found 12/22

$716

Wed 12/2412:20 pmSCL - MEX

1 stop12h 45mCopa Airlines

Thu 3/125:55 amMEX - SCL

1 stop14h 54mCopa Airlines

Deal found 12/23

$748

Wed 12/245:44 amSCL - MEX

1 stop21h 31mMultiple Airlines

Fri 12/2611:10 pmMEX - SCL

1 stop13h 10mMultiple Airlines

Deal found 12/20

$749

Fri 12/2612:20 pmSCL - MEX

1 stop14h 55mCopa Airlines

Tue 1/65:55 amMEX - SCL

1 stop19h 19mCopa Airlines

Deal found 12/22

$753

Tue 12/301:35 amSCL - MEX

2 stops21h 05mMultiple Airlines

Sun 1/411:10 pmMEX - SCL

1 stop13h 10mMultiple Airlines

Deal found 12/22

$759

Mon 12/229:10 amSCL - MEX

Nonstop8h 50mLATAM Airlines

Tue 1/67:50 pmMEX - SCL

Nonstop8h 40mLATAM Airlines

Deal found 12/21

$763

Sat 12/2712:20 pmSCL - MEX

1 stop14h 55mCopa Airlines

Fri 1/161:20 amMEX - SCL

1 stop16h 00mCopa Airlines

Deal found 12/22

$768

Best flights from Santiago to Mexico City
Discover carefully curated flight deals from Santiago to Mexico City that have cost, travel time, and layovers in mind to ensure you get the best travel experience. Data last updated December 23, 2025.

Sun 3/291:12 amSCL - MEX

1 stop20h 53mCopa Airlines

Sat 4/112:10 amMEX - SCL

1 stop22h 10mCopa Airlines

Deal found 12/22

$623

Tue 1/209:05 pmSCL - MEX

1 stop17h 05mMultiple Airlines

Tue 1/277:50 pmMEX - SCL

Nonstop8h 40mMultiple Airlines

Deal found 12/23

$643

Tue 5/124:09 amSCL - MEX

1 stop22h 06mCopa Airlines

Fri 5/295:50 amMEX - SCL

1 stop15h 36mCopa Airlines

Deal found 12/20

$651

Wed 4/154:17 amSCL - MEX

1 stop16h 48mCopa Airlines

Wed 4/225:50 amMEX - SCL

1 stop15h 36mCopa Airlines

Deal found 12/21

$651

Wed 5/64:09 amSCL - MEX

1 stop22h 06mCopa Airlines

Sat 5/301:20 amMEX - SCL

1 stop19h 23mCopa Airlines

Deal found 12/21

$651

Mon 5/2511:17 amSCL - MEX

1 stop14h 58mCopa Airlines

Fri 5/295:50 amMEX - SCL

1 stop15h 36mCopa Airlines

Deal found 12/21

$651

Wed 5/612:38 amSCL - MEX

1 stop20h 27mCopa Airlines

Sat 5/161:20 amMEX - SCL

1 stop20h 06mCopa Airlines

Deal found 12/21

$651

Fri 5/84:09 amSCL - MEX

1 stop22h 06mCopa Airlines

Tue 5/121:10 pmMEX - SCL

1 stop11h 10mCopa Airlines

Deal found 12/21

$651

Wed 4/224:17 amSCL - MEX

1 stop16h 48mCopa Airlines

Wed 5/69:50 amMEX - SCL

1 stop11h 36mCopa Airlines

Deal found 12/21

$651

Last-minute flights from Santiago to Mexico City
Discover last-minute flight deals from Santiago to Mexico City. Data last updated December 23, 2025 and is based on user searches.

Mon 12/225:12 amSCL - MEX

1 stop17h 08mCopa Airlines

Tue 1/65:55 amMEX - SCL

1 stop11h 25mCopa Airlines

Deal found 12/21

$644

Tue 12/231:08 amSCL - MEX

1 stop14h 02mCopa Airlines

Sat 12/272:00 amMEX - SCL

1 stop18h 41mCopa Airlines

Deal found 12/22

$628

Tue 12/233:23 amSCL - MEX

1 stop14h 07mCopa Airlines

Thu 1/152:00 amMEX - SCL

1 stop15h 20mCopa Airlines

Deal found 12/22

$648

Wed 12/2412:20 pmSCL - MEX

1 stop12h 45mCopa Airlines

Thu 1/151:10 pmMEX - SCL

1 stop12h 04mCopa Airlines

Deal found 12/22

$528

Fri 12/2612:20 pmSCL - MEX

1 stop12h 45mCopa Airlines

Sun 12/285:55 amMEX - SCL

1 stop14h 46mCopa Airlines

Deal found 12/22

$696

Wed 12/313:34 amSCL - MEX

1 stop11h 36mMultiple Airlines

Sun 1/411:10 pmMEX - SCL

1 stop13h 10mMultiple Airlines

Deal found 12/22

$693

Wed 1/144:35 amSCL - MEX

1 stop12h 15mLATAM Airlines

Thu 1/227:50 pmMEX - SCL

Nonstop8h 40mLATAM Airlines

Deal found 12/22

$688

Sun 1/189:00 amSCL - MEX

Nonstop8h 50mLATAM Airlines

Sun 1/257:50 pmMEX - SCL

Nonstop8h 40mLATAM Airlines

Deal found 12/21

$708

Tue 1/209:05 pmSCL - MEX

1 stop17h 05mMultiple Airlines

Tue 1/274:00 pmMEX - SCL

1 stop19h 05mMultiple Airlines

Deal found 12/23

$643

Tue 1/209:00 amSCL - MEX

Nonstop8h 50mLATAM Airlines

Tue 1/277:50 pmMEX - SCL

Nonstop8h 40mLATAM Airlines

Deal found 12/23

$656

Wed 1/214:25 pmSCL - MEX

1 stop22h 45mAvianca

Wed 6/1011:20 pmMEX - SCL

1 stop12h 05mAvianca

Deal found 12/21

$697

One-way flights from Santiago to Mexico City
Search for one-way flight options from Santiago to Mexico City. Find affordable one-way fares based on user searches. Data last updated December 23, 2025.

Sun 2/1512:35 pmSCL - MEX

1 stop25h 35mMultiple Airlines

Deal found 12/21

$273

Thu 2/194:25 pmSCL - MEX

1 stop13h 35mAvianca

Deal found 12/22

$277

Wed 1/2811:05 pmSCL - MEX

1 stop15h 05mMultiple Airlines

Deal found 12/23

$293

Fri 1/2312:35 pmSCL - MEX

1 stop25h 35mMultiple Airlines

Deal found 12/21

$302

Tue 2/39:05 pmSCL - MEX

1 stop17h 05mMultiple Airlines

Deal found 12/21

$303

Mon 3/91:35 amSCL - MEX

3 stops31h 10mMultiple Airlines

Deal found 12/21

$310

Wed 4/154:49 amSCL - MEX

1 stop16h 16mCopa Airlines

Deal found 12/22

$326

Sat 1/319:29 pmSCL - MEX

1 stop16h 41mMultiple Airlines

Deal found 12/21

$331

Mon 1/199:05 pmSCL - MEX

1 stop17h 05mMultiple Airlines

Deal found 12/20

$333

Tue 1/2012:35 pmSCL - MEX

1 stop25h 35mMultiple Airlines

Deal found 12/21

$339

Tue 2/2410:15 pmSCL - MEX

2 stops34h 30mMultiple Airlines

Deal found 12/21

$347

Find flight deals from Santiago to Mexico City

Most accurate provider	Gotogate 3 stars
Most trusted provider	Gotogate 3 stars
Round-trip from	$555 (Copa Airlines)
One-way from	$273 (Trip.com)
Popular in	January
Cheapest in	March
Average price	$592
Good round-trip deal	$588 or less
Good one-way deal	$347 or less

Provider with most accurate pricing for Santiago Arturo Merino Benitez-Mexico City Benito Juarez flight deals.

Search Deals

Provider most trusted by Cheapflights users for Santiago Arturo Merino Benitez-Mexico City Benito Juarez flights.

Search Deals

From Santiago Arturo Merino Benitez to Mexico City Benito Juarez

Search Deals

One-way flight from Santiago Arturo Merino Benitez to Mexico City Benito Juarez

Search Deals

Highest demand for flights based on searches. 3% potential increase in price ($19 potential increase over avg. RT price).

Search Deals

Cheapest flight prices on average. 0% potential price decrease ($5 potential savings vs. average RT price).

Search Deals

Average for round-trip flights in December 2025

Search Deals

Price to beat on a round-trip flight from Santiago Arturo Merino Benitez to Mexico City Benito Juarez.

Search Deals

Price to beat on a one-way flight from Santiago Arturo Merino Benitez to Mexico City Benito Juarez.

Search Deals

Cheapflights Fare Finder

Use the filters below to find and compare flights from Santiago to Mexico City that are best for you.

Fly from

Fly to

Route

Depart

Return

Price

SantiagoMexico City

SCL - MEX

SCLMEX

Santiago Arturo Merino Benitez

Sun 3/29

1:12 am-7:05 pm

1 stop20h 53m

Mexico City Benito Juarez

Sat 4/11

2:10 am-2:20 am

1 stop22h 10m

$623

SantiagoMexico City

SCL - MEX

SCLMEX

Santiago Arturo Merino Benitez

Tue 1/20

9:05 pm-11:10 am

1 stop17h 05m

Mexico City Benito Juarez

Tue 1/27

7:50 pm-7:30 am

Nonstop8h 40m

$643

SantiagoMexico City

SCL - MEX

SCLMEX

Santiago Arturo Merino Benitez

Tue 5/12

4:09 am-12:15 am

1 stop22h 06m

Mexico City Benito Juarez

Fri 5/29

5:50 am-11:26 pm

1 stop15h 36m

$651

SantiagoMexico City

SCL - MEX

SCLMEX

Santiago Arturo Merino Benitez

Wed 4/15

4:17 am-7:05 pm

1 stop16h 48m

Mexico City Benito Juarez

Wed 4/22

5:50 am-11:26 pm

1 stop15h 36m

$651

SantiagoMexico City

SCL - MEX

SCLMEX

Santiago Arturo Merino Benitez

Wed 5/6

4:09 am-12:15 am

1 stop22h 06m

Mexico City Benito Juarez

Sat 5/30

1:20 am-10:43 pm

1 stop19h 23m

$651

SantiagoMexico City

SCL - MEX

SCLMEX

Santiago Arturo Merino Benitez

Mon 5/25

11:17 am-12:15 am

1 stop14h 58m

Mexico City Benito Juarez

Fri 5/29

5:50 am-11:26 pm

1 stop15h 36m

$651

SantiagoMexico City

SCL - MEX

SCLMEX

Santiago Arturo Merino Benitez

Wed 5/6

12:38 am-7:05 pm

1 stop20h 27m

Mexico City Benito Juarez

Sat 5/16

1:20 am-11:26 pm

1 stop20h 06m

$651

SantiagoMexico City

SCL - MEX

SCLMEX

Santiago Arturo Merino Benitez

Fri 5/8

4:09 am-12:15 am

1 stop22h 06m

Mexico City Benito Juarez

Tue 5/12

1:10 pm-2:20 am

1 stop11h 10m

$651

SantiagoMexico City

SCL - MEX

SCLMEX

Santiago Arturo Merino Benitez

Wed 4/22

4:17 am-7:05 pm

1 stop16h 48m

Mexico City Benito Juarez

Wed 5/6

9:50 am-11:26 pm

1 stop11h 36m

$651

SantiagoMexico City

SCL - MEX

SCLMEX

Santiago Arturo Merino Benitez

Sun 2/15

12:35 pm-11:10 am

1 stop25h 35m

$273

Flights are sorted by cheapest round-trip flights first.

Deals found on 12/21

Showing 1-10 of 17 results

Compare providers for flights from Santiago to Mexico City

Use the table below to compare price accuracy, trust ratings, and cancellation policies for each provider offering flight deals from Santiago to Mexico City in December.

Provider	Price Accuracy	Trust Score*
eDreams	Price Accuracy3 stars	Trust Score*3 stars
FlightHub	Price Accuracy3 stars	Trust Score*1 star
Gotogate	Price Accuracy3 stars	Trust Score*3 stars
Cheapflightsfares	Price Accuracy3 stars	Trust Score*2 stars

*The Trust Score is based on feedback from users after their booking experience. It measures overall satisfaction, helping us identify issues like hidden fees, problems during the ticketing process, and the quality of customer service. This score is our best indicator of the provider's quality and reliability.

Most accurate provider: When it comes to deals on Santiago-Mexico City flights, users find the pricing of Gotogate to be most consistent on Cheapflights vs. Gotogate Users can find the same prices on Santiago-Mexico City flight deals on Cheapflights vs. Gotogate >95% of the time. Price accuracy is based on data collected from Santiago-Mexico City flight searches over the past month and is updated monthly.
Most trusted provider: When it comes to deals on Santiago-Mexico City flights, Cheapflights users trust Gotogate the most. Gotogate has received a user feedback score of 3 out of 3 stars (3 being the best), meaning they have been trusted the most by Cheapflights users looking for Santiago-Mexico City flight deals. Provider user feedback score is based on Cheapflights searches over the past month and is updated monthly.

Best time to book a flight from Santiago to Mexico City

Have a flexible travel schedule? Discover the best time to fly to Mexico City from Santiago with our price prediction graph.

Estimated round-trip price

Rates are based on past data. Find the cheapest month and day to book your flight based on your travel requirements, then search for cheap deals.

Cheapflights Insights

Everything you need to know about your flight from Santiago to Mexico City

Prices

Airlines

Delays

How far ahead should I book a flight from Santiago to Mexico City?

The best time to book flights from Santiago to Mexico City is 83 days before your desired departure date. The cost of your flight will likely increase significantly if you book two weeks in advance of your flight.

What is the cheapest month to book a flight from Santiago to Mexico City?

Currently, October is the cheapest month in which you can book a flight from Santiago to Mexico City (average of $318). Flying from Santiago to Mexico City in January is currently the most expensive (average of $481). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.

What is the cheapest time of day to fly from SCL to MEX?

One of the essential ways to save on airfare from Santiago to Mexico City is to remain as flexible as possible. Flights that are in the morning tend to be the most expensive. A flight at noon could potentially save you up to 37% on airfare.

How much does it cost to fly round-trip from Santiago to Mexico City?

Reviews of airlines servicing Mexico City

Read reviews from past customers who have flown Copa Airlines, LATAM Airlines, and Aeromexico from Santiago to Mexico City. Users can see the overall rating for each airline as well as how each is rated in terms of entertainment options, comfort, food, crew/service, and boarding process.

Copa Airlines

7.6

Good

1,558 reviews

Reviews

1 / 20

2.0

Mediocre

Maria,Dec 2025

PTY - SLA

Old plain no entertainment , no outlet for cell or computer! And online they said you have all that! Almost 6 hrs looking to the floor..terrible expirencw and I pay a lot of money for it

Copa Airlines

7.6

Good

1,558 reviews

Copa Airlines

7.6

Good

1,558 reviews

Reviews

1 / 20

2.0

Mediocre

Maria,Dec 2025

PTY - SLA

Old plain no entertainment , no outlet for cell or computer! And online they said you have all that! Almost 6 hrs looking to the floor..terrible expirencw and I pay a lot of money for it

LATAM Airlines

7.5

Good

1,894 reviews

Copa Airlines

7.6

Good

1,558 reviews

Reviews

1 / 20

2.0

Mediocre

Maria,Dec 2025

PTY - SLA

Old plain no entertainment , no outlet for cell or computer! And online they said you have all that! Almost 6 hrs looking to the floor..terrible expirencw and I pay a lot of money for it

Aeromexico

7.4

Good

1,626 reviews

Copa Airlines

7.6

Good

1,558 reviews

Reviews

1 / 20

2.0

Mediocre

Maria,Dec 2025

PTY - SLA

Old plain no entertainment , no outlet for cell or computer! And online they said you have all that! Almost 6 hrs looking to the floor..terrible expirencw and I pay a lot of money for it

Avianca

6.6

Okay

2,492 reviews

Copa Airlines

7.6

Good

1,558 reviews

Reviews

1 / 20

2.0

Mediocre

Maria,Dec 2025

PTY - SLA

Old plain no entertainment , no outlet for cell or computer! And online they said you have all that! Almost 6 hrs looking to the floor..terrible expirencw and I pay a lot of money for it

Related info for your journey

What airports do I use to fly from Santiago to Mexico City?
To fly from Santiago to Mexico City, you need to book a flight from Arturo Merino Benitez (SCL) to Benito Juarez (MEX). Nonstop flights to Mexico City Benito Juarez from Santiago Arturo Merino Benitez take 8h 40m on average. When it comes time to book airfare, you have a few options: there are 2 outbound flights from Arturo Merino Benitez to Benito Juarez offered by 4 different airlines.
How popular is this Santiago to Mexico City flight route?
The Santiago Arturo Merino Benitez to Mexico City Benito Juarez flight path was viewed by 7 users in the past month. Keep an eye out for changes in search interest prior to high and low season.
How long is the flight from Santiago to Mexico City?
Departing from Santiago to Mexico City will take you 8h 50m. There are 4096 mi between Santiago and Mexico City. When browsing for deals, the options you’ll see will be for both nonstop flights and flights with stops.
What are the cheapest airlines flying from Santiago to Mexico City round-trip?
Flying on Copa Airlines is currently your cheapest option to Mexico City, with prices starting at $256. Additional round-trip tickets that might be worth considering are offered by Aeromexico and Avianca, with the lowest prices starting at $344 and $487, respectively. Copa Airlines is 57% cheaper than the average price of flights available within the next 90 days to this destination.
What are the cheapest airlines to fly from Santiago to Mexico City one-way?
To fly one-way, consider booking your trip with Arajet, which is currently one of the cheapest options available, starting at $180. Avianca flights start at $233 while deals on Copa Airlines start at $241 one-way.
What are the most reliable airlines from Santiago to Mexico City?
Looking for the most reliable airlines to get you to your destination on time? Our data shows these are most likely to get you from Santiago to Mexico City on time: WestJet (88%), Aeromexico (88%), LATAM Airlines (47%).
What are the cheapest flights from Santiago to Mexico City?
Looking for the cheapest flight from Santiago to Mexico City? While on average our users pay $1,009, our data indicates the cheapest price to be $258. The most popular route (Santiago Arturo Merino Benitez - Mexico City Benito Juarez), is priced around $469.
Can I find deals for flights from Santiago to Mexico City that include hotel bookings?
Yes. In addition to deals on Santiago to Mexico City flights, Cheapflights offers vacation packages that include both flights and hotel.
How can I find direct flights from Santiago to Mexico City?
After entering your origin and destination, apply the non-stop filter on the search result page to find direct flights from Santiago to Mexico City.
Can I find deals for business class flights from Santiago to Mexico City?
Yes. Cheapflights offers flight deals from Santiago to Mexico City by cabin class. In addition to browsing deals, you can also filter by cabin class on the search results page after making a search.
What is the cheapest month to book a flight from Santiago to Mexico City?
Currently, October is the cheapest month in which you can book a flight from Santiago to Mexico City (average of $318). Flying from Santiago to Mexico City in January is currently the most expensive (average of $481). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.

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Other flights to Mexico City

Top 4 airlines flying from Santiago to Mexico City

Airline	Cheapest	Average	Flexibility	On-time
Copa Airlines	Cheapest$477	Average$638	FlexibilityNo cancel fee	On-time70%
Avianca	Cheapest$487	Average$570	FlexibilityNo cancel fee	On-time71%
LATAM Airlines	Cheapest$505	Average$692	FlexibilityNo cancel fee	On-time81%
Aeromexico	Cheapest$525	Average$603	FlexibilityNo cancel fee	On-timeN/A

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$273+ Cheap flights from Santiago (SCL) to Mexico City (MEX)

This is the cheapest one-way flight price found by a Cheapflights user in the last 72 hours by searching for a flight departing on 2/15. Fares are subject to change and may not be available on all flights or dates of travel.

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Cheapflights Tip: The best prices from Santiago Arturo Merino Benitez to Mexico City Benito Juarez are usually found in March or November, booked 83 days in advance, depart on a Tuesday or Thursday and return on a Thursday

Cheap flight deals from Santiago to Mexico City

Cheapest flights from Santiago to Mexico CityExplore the most affordable flight options available from Santiago to Mexico City. Find the lowest fares from popular airlines and budget airlines, with prices last updated on December 23, 2025.

Explore the most affordable flight options available from Santiago to Mexico City. Find the lowest fares from popular airlines and budget airlines, with prices last updated on December 23, 2025.

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Best time to book a flight from Santiago to Mexico City

Have a flexible travel schedule? Discover the best time to fly to Mexico City from Santiago with our price prediction graph.

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Everything you need to know about your flight from Santiago to Mexico City

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Weekly flight availability from Santiago to Mexico City

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Reviews of airlines servicing Mexico City

Read reviews from past customers who have flown Copa Airlines, LATAM Airlines, and Aeromexico from Santiago to Mexico City. Users can see the overall rating for each airline as well as how each is rated in terms of entertainment options, comfort, food, crew/service, and boarding process.

Related info for your journey

Find useful and relevant information for your journey from Santiago to Mexico City. Access travel guides, tips, and recommendations to enhance your travel experience. Get information about local attractions, weather, transportation options, and more.

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Cheapest flights from Santiago to Mexico City
Explore the most affordable flight options available from Santiago to Mexico City. Find the lowest fares from popular airlines and budget airlines, with prices last updated on December 23, 2025.