$168+ Cheap flights from La Crosse (LSE) to Mesa, AZ
This is the cheapest one-way flight price found by a Cheapflights user in the last 72 hours by searching for a flight departing on 10/11. Fares are subject to change and may not be available on all flights or dates of travel.
LSE — PHX
Sep 13 — Sep 201
Round-trip
1 adult, Economy
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Enter your travel information like dates, passengers, trip type (one-way or round trip), and preferred cabin class then click “Find deals”2. Select your favorite providers
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Cheapest flights from La Crosse to MesaExplore the most affordable flight options available from La Crosse to Mesa. Find the lowest fares from popular airlines and budget airlines, with prices last updated on August 14, 2026.
Explore the most affordable flight options available from La Crosse to Mesa. Find the lowest fares from popular airlines and budget airlines, with prices last updated on August 14, 2026.
This American Airlines deal was found by Cheapflights users on 8/12. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 9/1212:26 pm -
1 stop8h 32m
Sat 9/193:34 pm -
1 stop6h 46m
Deal found 8/12![American Airlines logo]()
$380
This American Airlines deal was found by Cheapflights users on 8/10. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 9/115:22 pm -
1 stop9h 00m
Mon 9/1412:24 am -
1 stop8h 58m
Deal found 8/10![American Airlines logo]()
$405
This American Airlines deal was found by Cheapflights users on 8/13. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 10/25:22 pm -
1 stop15h 23m
Fri 10/912:36 am -
1 stop15h 44m
Deal found 8/13![American Airlines logo]()
$410
This American Airlines deal was found by Cheapflights users on 8/11. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 9/115:22 pm -
1 stop17h 32m
Mon 9/143:34 pm -
1 stop17h 48m
Deal found 8/11![American Airlines logo]()
$422
This American Airlines deal was found by Cheapflights users on 8/11. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 12/166:53 pm -
1 stop7h 52m
Sun 12/205:03 am -
1 stop6h 16m
Deal found 8/11![American Airlines logo]()
$425
This American Airlines deal was found by Cheapflights users on 8/11. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 9/175:22 pm -
1 stop9h 00m
Sat 9/1912:24 am -
1 stop8h 58m
Deal found 8/11![American Airlines logo]()
$430
This American Airlines deal was found by Cheapflights users on 8/13. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 9/1012:26 pm -
1 stop12h 12m
Thu 9/176:56 pm -
1 stop14h 26m
Deal found 8/13![American Airlines logo]()
$434
Best flights from La Crosse to MesaDiscover carefully curated flight deals from La Crosse to Mesa that have cost, travel time, and layovers in mind to ensure you get the best travel experience. Data last updated August 14, 2026.
Discover carefully curated flight deals from La Crosse to Mesa that have cost, travel time, and layovers in mind to ensure you get the best travel experience. Data last updated August 14, 2026.
This American Airlines deal was found by Cheapflights users on 8/14. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 1/276:50 pm -
1 stop7h 44m
Wed 2/178:48 am -
1 stop8h 32m
Deal found 8/14![American Airlines logo]()
$380
This American Airlines deal was found by Cheapflights users on 8/10. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 9/115:22 pm -
1 stop9h 00m
Tue 9/1510:30 am -
2 stops11h 50m
Deal found 8/10![American Airlines logo]()
$411
This American Airlines deal was found by Cheapflights users on 8/11. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 11/56:49 pm -
1 stop7h 56m
Sun 11/85:00 am -
1 stop5h 52m
Deal found 8/11![American Airlines logo]()
$430
This American Airlines deal was found by Cheapflights users on 8/9. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 9/145:22 pm -
1 stop7h 16m
Mon 9/2112:15 pm -
2 stops10h 05m
Deal found 8/9![American Airlines logo]()
$436
This American Airlines deal was found by Cheapflights users on 8/14. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 9/115:22 pm -
1 stop17h 32m
Mon 9/143:34 pm -
1 stop17h 48m
Deal found 8/14![American Airlines logo]()
$480
This American Airlines deal was found by Cheapflights users on 8/11. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 10/136:50 pm -
1 stop7h 54m
Wed 10/213:17 pm -
1 stop6h 42m
Deal found 8/11![American Airlines logo]()
$480
This American Airlines deal was found by Cheapflights users on 8/14. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 9/145:22 pm -
1 stop17h 32m
Fri 9/186:02 pm -
1 stop15h 20m
Deal found 8/14![American Airlines logo]()
$493
Last-minute flights from La Crosse to MesaDiscover last-minute flight deals from La Crosse to Mesa. Data last updated August 14, 2026 and is based on user searches.
Discover last-minute flight deals from La Crosse to Mesa. Data last updated August 14, 2026 and is based on user searches.
This American Airlines deal was found by Cheapflights users on 8/10. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 8/153:14 pm -
1 stop8h 08m
Tue 8/183:55 pm -
1 stop6h 27m
Deal found 8/10![American Airlines logo]()
$446
This American Airlines deal was found by Cheapflights users on 8/13. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 9/1012:26 pm -
1 stop12h 12m
Thu 9/176:56 pm -
1 stop14h 26m
Deal found 8/13![American Airlines logo]()
$434
This American Airlines deal was found by Cheapflights users on 8/10. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 9/115:22 pm -
1 stop9h 00m
Mon 9/1412:24 am -
1 stop8h 58m
Deal found 8/10![American Airlines logo]()
$405
This American Airlines deal was found by Cheapflights users on 8/11. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 9/115:22 pm -
1 stop17h 32m
Mon 9/143:34 pm -
1 stop17h 48m
Deal found 8/11![American Airlines logo]()
$422
This American Airlines deal was found by Cheapflights users on 8/12. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 9/1212:26 pm -
1 stop8h 32m
Sat 9/193:34 pm -
1 stop6h 46m
Deal found 8/12![American Airlines logo]()
$380
This American Airlines deal was found by Cheapflights users on 8/11. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 9/175:22 pm -
1 stop9h 00m
Sat 9/1912:24 am -
1 stop8h 58m
Deal found 8/11![American Airlines logo]()
$430
One-way flights from La Crosse to MesaSearch for one-way flight options from La Crosse to Mesa. Find affordable one-way fares based on user searches. Data last updated August 14, 2026.
Search for one-way flight options from La Crosse to Mesa. Find affordable one-way fares based on user searches. Data last updated August 14, 2026.
This Kiwi.com deal was found by Cheapflights users on 8/14. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 10/1111:41 am -
3 stops52h 01m
Deal found 8/14![Multiple Airlines logo]()
$168
This American Airlines deal was found by Cheapflights users on 8/12. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 9/45:20 pm -
1 stop15h 13m
Deal found 8/12![American Airlines logo]()
$255
This American Airlines deal was found by Cheapflights users on 8/12. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 9/145:22 pm -
1 stop15h 23m
Deal found 8/12![American Airlines logo]()
$325
This American Airlines deal was found by Cheapflights users on 8/14. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 10/116:55 pm -
1 stop13h 55m
Deal found 8/14![American Airlines logo]()
$360
This American Airlines deal was found by Cheapflights users on 8/9. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 9/85:20 pm -
1 stop7h 23m
Deal found 8/9![American Airlines logo]()
$465
This American Airlines deal was found by Cheapflights users on 8/12. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 9/1512:26 pm -
2 stops10h 19m
Deal found 8/12![American Airlines logo]()
$471
This American Airlines deal was found by Cheapflights users on 8/9. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 9/75:20 pm -
1 stop15h 13m
Deal found 8/9![American Airlines logo]()
$477
Find flight deals from La Crosse to Mesa
Keep the following information in mind while searching for La Crosse to Mesa flight deals. Data was last updated August 14, 2026.
Round-trip from | $380 (American Airlines) |
|---|---|
One-way from | $168 (Kiwi.com) |
Popular in | September |
Cheapest in | February |
Average price | $585 |
Cheapflights Fare Finder
Customize your flight search to find flights from La Crosse to Mesa that fit within your specific budget. Explore options based on user searches and filter the results based on your desired price range. Find flights that match your budget for a cost-effective journey. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated August 14, 2026.
Use the filters below to find and compare flights from La Crosse to Mesa that are best for you.
Fly from
Fly to
Route
Depart
Return
Cheapest round-trip
La CrossePhoenix
LSE La Crosse - PHX Phoenix Sky Harbor Intl
LSEPHX
La Crosse
Wed 1/27
6:50 pm-1:34 am
1 stop7h 44m
Phoenix Sky Harbor Intl
Wed 2/17
8:48 am-6:20 pm
1 stop8h 32m
$380
La CrossePhoenix
LSE La Crosse - PHX Phoenix Sky Harbor Intl
LSEPHX
La Crosse
Fri 9/11
5:22 pm-12:22 am
1 stop9h 00m
Phoenix Sky Harbor Intl
Tue 9/15
10:30 am-12:20 am
2 stops11h 50m
$411
Quickest round-trip
La CrossePhoenix
LSE La Crosse - PHX Phoenix Sky Harbor Intl
LSEPHX
La Crosse
Thu 11/5
6:49 pm-1:45 am
1 stop7h 56m
Phoenix Sky Harbor Intl
Sun 11/8
5:00 am-11:52 am
1 stop5h 52m
$430
La CrossePhoenix
LSE La Crosse - PHX Phoenix Sky Harbor Intl
LSEPHX
La Crosse
Mon 9/14
5:22 pm-10:38 pm
1 stop7h 16m
Phoenix Sky Harbor Intl
Mon 9/21
12:15 pm-12:20 am
2 stops10h 05m
$436
La CrossePhoenix
LSE La Crosse - PHX Phoenix Sky Harbor Intl
LSEPHX
La Crosse
Fri 9/11
5:22 pm-8:54 am
1 stop17h 32m
Phoenix Sky Harbor Intl
Mon 9/14
3:34 pm-11:22 am
1 stop17h 48m
$480
La CrossePhoenix
LSE La Crosse - PHX Phoenix Sky Harbor Intl
LSEPHX
La Crosse
Tue 10/13
6:50 pm-12:44 am
1 stop7h 54m
Phoenix Sky Harbor Intl
Wed 10/21
3:17 pm-11:59 pm
1 stop6h 42m
$480
La CrossePhoenix
LSE La Crosse - PHX Phoenix Sky Harbor Intl
LSEPHX
La Crosse
Mon 9/14
5:22 pm-8:54 am
1 stop17h 32m
Phoenix Sky Harbor Intl
Fri 9/18
6:02 pm-11:22 am
1 stop15h 20m
$493
Cheapest one-way
La CrossePhoenix
LSE La Crosse - PHX Phoenix Sky Harbor Intl
LSEPHX
La Crosse
Fri 9/4
5:20 pm-6:33 am
1 stop15h 13m
$255
La CrossePhoenix
LSE La Crosse - PHX Phoenix Sky Harbor Intl
LSEPHX
La Crosse
Mon 9/14
5:22 pm-6:45 am
1 stop15h 23m
$325
La CrossePhoenix
LSE La Crosse - PHX Phoenix Sky Harbor Intl
LSEPHX
La Crosse
Tue 9/15
5:53 am-3:35 pm
1 stop11h 42m
$325
Showing 1-10 of 13 resultsSorted by cheapest first
Best time to book a flight from La Crosse to Mesa
Have a flexible travel schedule? Discover the best time to fly to Mesa from La Crosse with our price prediction graph.
LSE-PHX
Estimated round-trip price
Rates are based on past data. Find the cheapest month and day to book your flight based on your travel requirements, then search for cheap deals.
Cheapflights Insights
Everything you need to know about your flight from La Crosse to Mesa
LSE-MS9
LSE-PHX
What is the cheapest time of day to fly from LSE to MS9?
Find hourly flight availability from La Crosse to Mesa. Discover flight options and departure times throughout the day, allowing you to choose a departure time that suits your schedule. Data last updated August 14, 2026.
When flying from La Crosse to Mesa, the time of day you fly usually plays a role in the price. Save by searching for a flight in the evening, which can drop the price by up to 34% versus a flight in the afternoon.
Reviews of airlines servicing Mesa
Get insights into the airlines that provide service to Mesa. Read reviews, discover amenities, and learn about the overall travel experience offered by airlines. Use this information to make informed decisions when choosing an airline for your flight to Mesa. Reviews last updated August 14, 2026.
Read through reviews of airlines operating flights from La Crosse to Mesa, such as American Airlines. Reviews also offer insight into each airline's entertainment options, comfort, food, crew/service, and boarding process.
Crew
7.9
Food
6.4
Overall
7.1
Comfort
7.2
Boarding
7.5
Entertainment
6.8
Reviews
1 / 20
6.0
GoodKristin,Jul 2026
DCA - PHX
Crew
7.9
Food
6.4
Overall
7.1
Comfort
7.2
Boarding
7.5
Entertainment
6.8
Reviews
1 / 20
6.0
GoodKristin,Jul 2026
DCA - PHX
Related info for your journey
Find useful and relevant information for your journey from La Crosse to Mesa. Access travel guides, tips, and recommendations to enhance your travel experience. Get information about local attractions, weather, transportation options, and more.
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Alternative routes for La Crosse to Mesa
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Complete your trip
Complete your trip to Mesa by adding a car rental and/or hotel reservation to your travel itinerary.
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La Crosse and Mesa flights
Browse other La Crosse and Mesa flight options. Last updated on August 14, 2026.
Other flights from La Crosse
Browse through other flights departing from La Crosse. Flights are based on user searches made on Cheapflights and were last updated on August 14, 2026.
Popular flight searches
Check out other popular destinations found by fellow travelers in 2026
La Crosse to Mesa flights
Consider these flights traveling from La Crosse to Mesa.
Top 2 airlines flying from La Crosse to Mesa
Discover the top 2 airlines that operate flights from La Crosse to Mesa. Compare their services, reliability, and customer satisfaction ratings to choose the airline that best suits your travel preferences and needs. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated August 14, 2026.
| Airline | Cheapest | Average | Flexibility | On-time |
|---|---|---|---|---|
| Cheapest$107 | Average$142 | FlexibilityNo cancel fee | On-time88% | |
| Cheapest$338 | Average$487 | FlexibilityNo cancel fee | On-time71% |