$290+ Cheap flights from La Crosse (LSE) to Mesa, AZ
This is the cheapest one-way flight price found by a Cheapflights user in the last 72 hours by searching for a flight departing on 4/10. Fares are subject to change and may not be available on all flights or dates of travel.
LSE — PHX
Apr 10 — Apr 171
Round-trip
1 adult, Economy
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Find cheap flights from La Crosse to Mesa with Cheapflights
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Enter your travel information like dates, passengers, trip type (one-way or round trip), and preferred cabin class then click “Find deals”2. Select your favorite providers
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Cheapest flights from La Crosse to MesaExplore the most affordable flight options available from La Crosse to Mesa. Find the lowest fares from popular airlines and budget airlines, with prices last updated on March 11, 2026.
Explore the most affordable flight options available from La Crosse to Mesa. Find the lowest fares from popular airlines and budget airlines, with prices last updated on March 11, 2026.
This American Airlines deal was found by Cheapflights users on 3/9. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 4/246:37 pm
LSE
- PHX
1 stop7h 22m
American Airlines
Fri 5/111:59 pm
PHX
- LSE
1 stop7h 36m
American Airlines
Deal found 3/9![American Airlines logo]()
$298
This American Airlines deal was found by Cheapflights users on 3/8. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 4/176:37 pm
LSE
- PHX
1 stop7h 22m
American Airlines
Fri 4/243:35 pm
PHX
- LSE
1 stop6h 19m
American Airlines
Deal found 3/8![American Airlines logo]()
$300
This American Airlines deal was found by Cheapflights users on 3/9. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 4/1110:05 am
LSE
- PHX
2 stops9h 13m
American Airlines
Tue 4/1411:59 pm
PHX
- LSE
1 stop7h 36m
American Airlines
Deal found 3/9![American Airlines logo]()
$304
This American Airlines deal was found by Cheapflights users on 3/9. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 11/26:02 pm
LSE
- PHX
1 stop6h 50m
American Airlines
Wed 11/114:30 pm
PHX
- LSE
1 stop6h 19m
American Airlines
Deal found 3/9![American Airlines logo]()
$348
This American Airlines deal was found by Cheapflights users on 3/9. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 4/106:37 pm
LSE
- PHX
1 stop7h 22m
American Airlines
Mon 4/138:34 pm
PHX
- LSE
2 stops11h 01m
American Airlines
Deal found 3/9![American Airlines logo]()
$384
This American Airlines deal was found by Cheapflights users on 3/10. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 3/236:29 pm
LSE
- PHX
1 stop6h 21m
American Airlines
Mon 3/3011:51 pm
PHX
- LSE
1 stop7h 27m
American Airlines
Deal found 3/10![American Airlines logo]()
$403
This American Airlines deal was found by Cheapflights users on 3/8. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 4/166:37 pm
LSE
- PHX
1 stop7h 22m
American Airlines
Wed 5/62:30 pm
PHX
- LSE
1 stop7h 24m
American Airlines
Deal found 3/8![American Airlines logo]()
$419
Best flights from La Crosse to MesaDiscover carefully curated flight deals from La Crosse to Mesa that have cost, travel time, and layovers in mind to ensure you get the best travel experience. Data last updated March 11, 2026.
Discover carefully curated flight deals from La Crosse to Mesa that have cost, travel time, and layovers in mind to ensure you get the best travel experience. Data last updated March 11, 2026.
This American Airlines deal was found by Cheapflights users on 3/8. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 5/16:37 pm
LSE
- PHX
1 stop7h 22m
American Airlines
Tue 5/512:29 pm
PHX
- LSE
2 stops9h 25m
American Airlines
Deal found 3/8![American Airlines logo]()
$304
This United Airlines deal was found by Cheapflights users on 3/9. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 6/139:43 am
LSE
- PHX
1 stop10h 10m
United Airlines
Sun 6/1411:50 pm
PHX
- LSE
1 stop16h 20m
United Airlines
Deal found 3/9![United Airlines logo]()
$654
This American Airlines deal was found by Cheapflights users on 3/7. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 4/2410:05 am
LSE
- PHX
2 stops9h 13m
American Airlines
Mon 4/2711:59 pm
PHX
- LSE
1 stop7h 36m
American Airlines
Deal found 3/7![American Airlines logo]()
$424
This American Airlines deal was found by Cheapflights users on 3/8. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 4/1710:05 am
LSE
- PHX
2 stops9h 13m
American Airlines
Fri 4/243:35 pm
PHX
- LSE
1 stop6h 19m
American Airlines
Deal found 3/8![American Airlines logo]()
$426
This American Airlines deal was found by Cheapflights users on 3/8. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 3/246:29 pm
LSE
- PHX
1 stop6h 21m
American Airlines
Tue 3/315:05 am
PHX
- LSE
1 stop16h 31m
American Airlines
Deal found 3/8![American Airlines logo]()
$440
This American Airlines deal was found by Cheapflights users on 3/10. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 4/66:29 pm
LSE
- PHX
1 stop14h 23m
American Airlines
Fri 4/1011:50 am
PHX
- LSE
2 stops10h 04m
American Airlines
Deal found 3/10![American Airlines logo]()
$588
This American Airlines deal was found by Cheapflights users on 3/6. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 3/245:09 am
LSE
- PHX
1 stop8h 38m
American Airlines
Sun 4/55:05 am
PHX
- LSE
1 stop10h 54m
American Airlines
Deal found 3/6![American Airlines logo]()
$660
This American Airlines deal was found by Cheapflights users on 3/6. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 3/236:29 pm
LSE
- PHX
1 stop6h 21m
American Airlines
Sun 4/55:05 am
PHX
- LSE
1 stop10h 54m
American Airlines
Deal found 3/6![American Airlines logo]()
$660
Last-minute flights from La Crosse to MesaDiscover last-minute flight deals from La Crosse to Mesa. Data last updated March 11, 2026 and is based on user searches.
Discover last-minute flight deals from La Crosse to Mesa. Data last updated March 11, 2026 and is based on user searches.
This American Airlines deal was found by Cheapflights users on 3/10. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 3/236:29 pm
LSE
- PHX
1 stop6h 21m
American Airlines
Mon 3/3011:51 pm
PHX
- LSE
1 stop7h 27m
American Airlines
Deal found 3/10![American Airlines logo]()
$403
This American Airlines deal was found by Cheapflights users on 3/9. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 3/246:29 pm
LSE
- PHX
1 stop6h 21m
American Airlines
Tue 3/3111:51 pm
PHX
- LSE
1 stop9h 10m
American Airlines
Deal found 3/9![American Airlines logo]()
$428
This American Airlines deal was found by Cheapflights users on 3/9. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 4/106:37 pm
LSE
- PHX
1 stop7h 22m
American Airlines
Mon 4/138:34 pm
PHX
- LSE
2 stops11h 01m
American Airlines
Deal found 3/9![American Airlines logo]()
$384
This American Airlines deal was found by Cheapflights users on 3/9. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 4/1110:05 am
LSE
- PHX
2 stops9h 13m
American Airlines
Tue 4/1411:59 pm
PHX
- LSE
1 stop7h 36m
American Airlines
Deal found 3/9![American Airlines logo]()
$304
This American Airlines deal was found by Cheapflights users on 3/8. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 4/166:37 pm
LSE
- PHX
1 stop7h 22m
American Airlines
Wed 5/62:30 pm
PHX
- LSE
1 stop7h 24m
American Airlines
Deal found 3/8![American Airlines logo]()
$419
This American Airlines deal was found by Cheapflights users on 3/8. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 4/176:37 pm
LSE
- PHX
1 stop7h 22m
American Airlines
Fri 4/243:35 pm
PHX
- LSE
1 stop6h 19m
American Airlines
Deal found 3/8![American Airlines logo]()
$300
This American Airlines deal was found by Cheapflights users on 3/9. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 4/246:37 pm
LSE
- PHX
1 stop7h 22m
American Airlines
Fri 5/111:59 pm
PHX
- LSE
1 stop7h 36m
American Airlines
Deal found 3/9![American Airlines logo]()
$298
One-way flights from La Crosse to MesaSearch for one-way flight options from La Crosse to Mesa. Find affordable one-way fares based on user searches. Data last updated March 11, 2026.
Search for one-way flight options from La Crosse to Mesa. Find affordable one-way fares based on user searches. Data last updated March 11, 2026.
This American Airlines deal was found by Cheapflights users on 3/8. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 4/106:37 pm
LSE
- PHX
1 stop14h 15m
American Airlines
Deal found 3/8![American Airlines logo]()
$290
This American Airlines deal was found by Cheapflights users on 3/10. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 4/96:37 pm
LSE
- PHX
1 stop7h 22m
American Airlines
Deal found 3/10![American Airlines logo]()
$318
This American Airlines deal was found by Cheapflights users on 3/10. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 5/95:40 am
LSE
- PHX
2 stops9h 25m
American Airlines
Deal found 3/10![American Airlines logo]()
$324
This American Airlines deal was found by Cheapflights users on 3/7. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 5/510:05 am
LSE
- PHX
1 stop5h 57m
American Airlines
Deal found 3/7![American Airlines logo]()
$330
This American Airlines deal was found by Cheapflights users on 3/7. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 5/710:05 am
LSE
- PHX
1 stop5h 57m
American Airlines
Deal found 3/7![American Airlines logo]()
$348
This American Airlines deal was found by Cheapflights users on 3/9. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 3/306:29 pm
LSE
- PHX
1 stop6h 21m
American Airlines
Deal found 3/9![American Airlines logo]()
$358
This American Airlines deal was found by Cheapflights users on 3/9. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 3/315:09 am
LSE
- PHX
2 stops12h 28m
American Airlines
Deal found 3/9![American Airlines logo]()
$370
This American Airlines deal was found by Cheapflights users on 3/9. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 4/36:29 pm
LSE
- PHX
2 stops22h 46m
American Airlines
Deal found 3/9![American Airlines logo]()
$377
This American Airlines deal was found by Cheapflights users on 3/8. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 3/245:09 am
LSE
- PHX
1 stop5h 58m
American Airlines
Deal found 3/8![American Airlines logo]()
$379
Find flight deals from La Crosse to Mesa
Keep the following information in mind while searching for La Crosse to Mesa flight deals. Data was last updated March 11, 2026.
Round-trip from | $298 (American Airlines) |
|---|---|
One-way from | $290 (American Airlines) |
Cheapflights Fare Finder
Customize your flight search to find flights from La Crosse to Mesa that fit within your specific budget. Explore options based on user searches and filter the results based on your desired price range. Find flights that match your budget for a cost-effective journey. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated March 11, 2026.
Use the filters below to find and compare flights from La Crosse to Mesa that are best for you.
Fly from
Fly to
Route
Depart
Return
Cheapest round-trip
La CrossePhoenix
LSE - PHX
LSEPHX
La Crosse
Fri 5/1
6:37 pm-11:59 pm
1 stop7h 22m
Phoenix Sky Harbor Intl
Tue 5/5
12:29 pm-11:54 pm
2 stops9h 25m
$304
La CrossePhoenix
LSE - PHX
LSEPHX
La Crosse
Fri 4/24
10:05 am-5:18 pm
2 stops9h 13m
Phoenix Sky Harbor Intl
Mon 4/27
11:59 pm-9:35 am
1 stop7h 36m
$424
Quickest round-trip
La CrossePhoenix
LSE - PHX
LSEPHX
La Crosse
Fri 4/17
10:05 am-5:18 pm
2 stops9h 13m
Phoenix Sky Harbor Intl
Fri 4/24
3:35 pm-11:54 pm
1 stop6h 19m
$426
La CrossePhoenix
LSE - PHX
LSEPHX
La Crosse
Tue 3/24
6:29 pm-10:50 pm
1 stop6h 21m
Phoenix Sky Harbor Intl
Tue 3/31
5:05 am-11:36 pm
1 stop16h 31m
$440
La CrossePhoenix
LSE - PHX
LSEPHX
La Crosse
Mon 4/6
6:29 pm-6:52 am
1 stop14h 23m
Phoenix Sky Harbor Intl
Fri 4/10
11:50 am-11:54 pm
2 stops10h 04m
$588
La CrossePhoenix
LSE - PHX
LSEPHX
La Crosse
Sat 6/13
9:43 am-5:53 pm
1 stop10h 10m
Phoenix Sky Harbor Intl
Sun 6/14
11:50 pm-6:10 pm
1 stop16h 20m
$654
La CrossePhoenix
LSE - PHX
LSEPHX
La Crosse
Tue 3/24
5:09 am-11:47 am
1 stop8h 38m
Phoenix Sky Harbor Intl
Sun 4/5
5:05 am-5:59 pm
1 stop10h 54m
$660
La CrossePhoenix
LSE - PHX
LSEPHX
La Crosse
Mon 3/23
6:29 pm-10:50 pm
1 stop6h 21m
Phoenix Sky Harbor Intl
Sun 4/5
5:05 am-5:59 pm
1 stop10h 54m
$660
Cheapest one-way
La CrossePhoenix
LSE - PHX
LSEPHX
La Crosse
Fri 4/10
6:37 pm-6:52 am
1 stop14h 15m
$290
La CrossePhoenix
LSE - PHX
LSEPHX
La Crosse
Thu 4/9
6:37 pm-11:59 pm
1 stop7h 22m
$318
Showing 1-10 of 18 resultsSorted by cheapest first
Best time to book a flight from La Crosse to Mesa
Have a flexible travel schedule? Discover the best time to fly to Mesa from La Crosse with our price prediction graph.
LSE-PHX
Estimated round-trip price
Rates are based on past data. Find the cheapest month and day to book your flight based on your travel requirements, then search for cheap deals.
Cheapflights Insights
Everything you need to know about your flight from La Crosse to Mesa
LSE-MS9
LSE-PHX
What is the cheapest month to book a flight from La Crosse to Mesa?
Currently, May is the cheapest month in which you can book a flight from La Crosse to Mesa (average of $193). Flying from La Crosse to Mesa in March is currently the most expensive (average of $320). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.
What is the cheapest time of day to fly from LSE to MS9?
Find hourly flight availability from La Crosse to Mesa. Discover flight options and departure times throughout the day, allowing you to choose a departure time that suits your schedule. Data last updated March 11, 2026.
Regardless of the time of day you decide to fly, the ticket price will remain around the same. Book flights from La Crosse to Mesa as you normally would.
Reviews of airlines servicing Mesa
Get insights into the airlines that provide service to Mesa. Read reviews, discover amenities, and learn about the overall travel experience offered by airlines. Use this information to make informed decisions when choosing an airline for your flight to Mesa. Reviews last updated March 11, 2026.
Read through reviews of airlines operating flights from La Crosse to Mesa, such as American Airlines. Reviews also offer insight into each airline's entertainment options, comfort, food, crew/service, and boarding process.
Entertainment
6.9
Comfort
7.2
Food
6.4
Overall
7.1
Crew
7.9
Boarding
7.5
Reviews
1 / 20
2.0
MediocreAnonymous,Mar 2026
MIA - SFO
Entertainment
6.9
Comfort
7.2
Food
6.4
Overall
7.1
Crew
7.9
Boarding
7.5
Reviews
1 / 20
2.0
MediocreAnonymous,Mar 2026
MIA - SFO
Related info for your journey
Find useful and relevant information for your journey from La Crosse to Mesa. Access travel guides, tips, and recommendations to enhance your travel experience. Get information about local attractions, weather, transportation options, and more.
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Complete your trip
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La Crosse and Mesa flights
Browse other La Crosse and Mesa flight options. Last updated on March 11, 2026.
Other flights from La Crosse
Browse through other flights departing from La Crosse. Flights are based on user searches made on Cheapflights and were last updated on March 11, 2026.
Popular flight searches
Check out other popular destinations found by fellow travelers in 2026
La Crosse to Mesa flights
Consider these flights traveling from La Crosse to Mesa.
Top 2 airlines flying from La Crosse to Mesa
Discover the top 2 airlines that operate flights from La Crosse to Mesa. Compare their services, reliability, and customer satisfaction ratings to choose the airline that best suits your travel preferences and needs. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated March 11, 2026.
| Airline | Cheapest | Average | Flexibility | On-time |
|---|---|---|---|---|
| Cheapest$172 | Average$292 | FlexibilityNo cancel fee | On-time88% | |
| Cheapest$514 | Average$630 | FlexibilityNo cancel fee | On-time71% |