$398+ Cheap flights from La Crosse (LSE) to Mesa, AZ
This is the cheapest one-way flight price found by a Cheapflights user in the last 72 hours by searching for a flight departing on 12/14. Fares are subject to change and may not be available on all flights or dates of travel.
Find cheap flights from La Crosse to Mesa with Cheapflights
1. Tell us where you want to go
Enter your travel information like dates, passengers, trip type (one-way or round trip), and preferred cabin class then click “Find deals”2. Select your favorite providers
We find the providers serving your travel needs. Choose up to four travel providers to compare side-by-side for flights, hotels, or car rentals.3. Compare prices and book
Review each provider’s pricing and select the best option for you! Book through your favorite provider’s website for a seamless experience.Cheap flight deals from La Crosse to Mesa
Keep the following information in mind while searching for La Crosse to Mesa flight deals. Data was last updated December 1, 2025.
Round-trip from | $513 (American Airlines) |
|---|---|
One-way from | $398 (American Airlines) |
Find flight deals from La Crosse to Mesa
Cheapest flights from La Crosse to MesaExplore the most affordable flight options available from La Crosse to Mesa. Find the lowest fares from popular airlines and budget airlines, with prices last updated on December 1, 2025.
Explore the most affordable flight options available from La Crosse to Mesa. Find the lowest fares from popular airlines and budget airlines, with prices last updated on December 1, 2025.
This American Airlines deal was found by Cheapflights users on 11/29. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
This American Airlines deal was found by Cheapflights users on 11/30. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
This American Airlines deal was found by Cheapflights users on 11/29. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Cheapflights Fare Finder
Use the filters below to find and compare flights from La Crosse to Mesa that are best for you.
Fly from
Fly to
Route
Depart
Return
Price
La CrossePhoenix
LSE - PHX
LSEPHX
La Crosse
Fri 1/16
5:08 pm-8:04 am
1 stop15h 56m
Phoenix Sky Harbor Intl
Tue 1/20
8:00 pm-11:07 am
1 stop14h 07m
La CrossePhoenix
LSE - PHX
LSEPHX
La Crosse
Sat 4/4
10:09 am-3:29 pm
1 stop7h 20m
Phoenix Sky Harbor Intl
Sat 4/11
6:45 am-3:58 pm
1 stop7h 13m
La CrossePhoenix
LSE - PHX
LSEPHX
La Crosse
Thu 3/12
6:28 pm-10:54 pm
1 stop6h 26m
Phoenix Sky Harbor Intl
Wed 3/18
11:59 pm-9:39 am
1 stop7h 40m
La CrossePhoenix
LSE - PHX
LSEPHX
La Crosse
Fri 2/20
6:21 pm-11:51 pm
1 stop6h 30m
Phoenix Sky Harbor Intl
Sun 2/22
12:59 am-9:32 am
1 stop7h 33m
La CrossePhoenix
LSE - PHX
LSEPHX
La Crosse
Wed 2/25
10:03 am-4:33 pm
1 stop7h 30m
Phoenix Sky Harbor Intl
Sun 3/1
12:59 am-9:32 am
1 stop7h 33m
La CrossePhoenix
LSE - PHX
LSEPHX
La Crosse
Thu 3/5
6:21 pm-11:51 pm
1 stop6h 30m
Phoenix Sky Harbor Intl
Wed 3/11
11:59 pm-9:39 am
1 stop7h 40m
La CrossePhoenix
LSE - PHX
LSEPHX
La Crosse
Sun 12/14
9:54 am-3:08 pm
1 stop6h 14m
Best time to book a flight from La Crosse to Mesa
Have a flexible travel schedule? Discover the best time to fly to Mesa from La Crosse with our price prediction graph.
Cheapflights Insights
Everything you need to know about your flight from La Crosse to Mesa
What is the cheapest month to book a flight from La Crosse to Mesa?
Currently, May is the cheapest month in which you can book a flight from La Crosse to Mesa (average of $193). Flying from La Crosse to Mesa in March is currently the most expensive (average of $306). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.
What is the cheapest time of day to fly from LSE to MS9?
Find hourly flight availability from La Crosse to Mesa. Discover flight options and departure times throughout the day, allowing you to choose a departure time that suits your schedule. Data last updated December 1, 2025.
When flying from La Crosse to Mesa, the time of day you fly usually plays a role in the price. Save by searching for a flight in the evening, which can drop the price by up to 65% versus a flight at noon.
Reviews of airlines servicing Mesa
Get insights into the airlines that provide service to Mesa. Read reviews, discover amenities, and learn about the overall travel experience offered by airlines. Use this information to make informed decisions when choosing an airline for your flight to Mesa. Reviews last updated December 1, 2025.
Read through reviews of airlines operating flights from La Crosse to Mesa, such as American Airlines. Reviews also offer insight into each airline's entertainment options, comfort, food, crew/service, and boarding process.
Crew
Entertainment
Overall
Food
Comfort
Boarding
Reviews
Monica,Nov 2025
JAC - DFW
Crew
Entertainment
Overall
Food
Comfort
Boarding
Reviews
Monica,Nov 2025
JAC - DFW
Related info for your journey
Find useful and relevant information for your journey from La Crosse to Mesa. Access travel guides, tips, and recommendations to enhance your travel experience. Get information about local attractions, weather, transportation options, and more.
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Alternative routes for La Crosse to Mesa
See prices for flight routes from nearby airports that may be better suited for you.
Top airline flying from La Crosse to Mesa
Discover the top airline that operate flights from La Crosse to Mesa. Compare their services, reliability, and customer satisfaction ratings to choose the airline that best suits your travel preferences and needs. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated December 1, 2025.
| Airline | Cheapest | Average | Flexibility | On-time |
|---|---|---|---|---|
| Cheapest$565 | Average$640 | FlexibilityNo cancel fee | On-time71% |