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Mesa

$504+ Cheap flights from La Crosse (LSE) to Mesa, AZ

This is the cheapest one-way flight price found by a Cheapflights user in the last 72 hours by searching for a flight departing on 11/5. Fares are subject to change and may not be available on all flights or dates of travel.
LSE — PHX
Oct 15 — Oct 221
Wed 10/15
Wed 10/22
1 adult, Economy
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Cheap flight deals from La Crosse to Mesa

Keep the following information in mind while searching for La Crosse to Mesa flight deals. Data was last updated September 15, 2025.

Round-trip from

$550
(American Airlines)

One-way from

$504
(American Airlines)
From La Crosse to Mesa
Search Deals
One-way flight from La Crosse to Mesa
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Find flight deals from La Crosse to Mesa

Cheapest flights from La Crosse to Mesa
Explore the most affordable flight options available from La Crosse to Mesa. Find the lowest fares from popular airlines and budget airlines, with prices last updated on September 15, 2025.

This American Airlines deal was found by Cheapflights users on 9/14. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 12/126:10 pmLSE - PHX
1 stop6h 42mAmerican Airlines
Sun 12/144:20 pmPHX - LSE
1 stop6h 32mAmerican Airlines
Deal found 9/14$570
This American Airlines deal was found by Cheapflights users on 9/15. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 10/86:00 amLSE - PHX
1 stop8h 35mAmerican Airlines
Sat 10/113:25 pmPHX - LSE
1 stop6h 01mAmerican Airlines
Deal found 9/15$592
This American Airlines deal was found by Cheapflights users on 9/15. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 9/306:00 amLSE - PHX
1 stop9h 06mAmerican Airlines
Sat 10/411:54 amPHX - LSE
2 stops8h 10mAmerican Airlines
Deal found 9/15$598
This American Airlines deal was found by Cheapflights users on 9/12. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 12/96:00 amLSE - PHX
1 stop15h 23mAmerican Airlines
Sat 12/135:30 amPHX - LSE
1 stop11h 02mAmerican Airlines
Deal found 9/12$605
This American Airlines deal was found by Cheapflights users on 9/13. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 12/136:00 amLSE - PHX
1 stop6h 55mAmerican Airlines
Tue 12/163:25 pmPHX - LSE
1 stop5h 38mAmerican Airlines
Deal found 9/13$610
This American Airlines deal was found by Cheapflights users on 9/14. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 9/206:00 amLSE - PHX
1 stop9h 06mAmerican Airlines
Mon 9/223:35 pmPHX - LSE
1 stop5h 42mAmerican Airlines
Deal found 9/14$611

Cheapflights Fare Finder

 
Customize your flight search to find flights from La Crosse to Mesa that fit within your specific budget. Explore options based on user searches and filter the results based on your desired price range. Find flights that match your budget for a cost-effective journey. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated September 15, 2025.
Use the filters below to find and compare flights from La Crosse to Mesa that are best for you.

Fly from

La Crosse

Fly to

Mesa

Route

Depart

Return

Price

La CrossePhoenix

LSE - PHX

LSEPHX

La Crosse

Fri 1/30

4:45 pm-9:49 pm

1 stop6h 04m

Phoenix Sky Harbor Intl

Wed 2/4

7:40 am-4:03 pm

1 stop7h 23m

$550

La CrossePhoenix

LSE - PHX

LSEPHX

La Crosse

Fri 12/12

6:10 pm-11:52 pm

1 stop6h 42m

Phoenix Sky Harbor Intl

Sun 12/14

4:20 pm-11:52 pm

1 stop6h 32m

$570

La CrossePhoenix

LSE - PHX

LSEPHX

La Crosse

Fri 2/27

6:26 pm-11:31 pm

1 stop6h 05m

Phoenix Sky Harbor Intl

Sun 3/1

5:00 am-2:18 pm

1 stop8h 18m

$570

La CrossePhoenix

LSE - PHX

LSEPHX

La Crosse

Tue 12/9

6:00 am-8:23 pm

1 stop15h 23m

Phoenix Sky Harbor Intl

Sat 12/13

5:30 am-5:32 pm

1 stop11h 02m

$605

La CrossePhoenix

LSE - PHX

LSEPHX

La Crosse

Wed 2/25

6:05 am-11:38 am

1 stop6h 33m

Phoenix Sky Harbor Intl

Tue 3/3

7:15 am-2:18 pm

1 stop6h 03m

$610

La CrossePhoenix

LSE - PHX

LSEPHX

La Crosse

Wed 11/5

9:59 am-4:34 pm

1 stop7h 35m

$504

Flights are sorted by cheapest round-trip flights first.

Deals found on 9/13

Best time to book a flight from La Crosse to Mesa

Have a flexible travel schedule? Discover the best time to fly to Mesa from La Crosse with our price prediction graph.
Estimated round-trip price
Rates are based on past data. Find the cheapest month and day to book your flight based on your travel requirements, then search for cheap deals.

Cheapflights Insights

Everything you need to know about your flight from La Crosse to Mesa

What is the cheapest month to book a flight from La Crosse to Mesa?

Currently, January is the cheapest month in which you can book a flight from La Crosse to Mesa (average of $258). Flying from La Crosse to Mesa in March is currently the most expensive (average of $337). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.

Reviews of airlines servicing Mesa

Get insights into the airlines that provide service to Mesa. Read reviews, discover amenities, and learn about the overall travel experience offered by airlines. Use this information to make informed decisions when choosing an airline for your flight to Mesa. Reviews last updated September 15, 2025.
Read through reviews of airlines operating flights from La Crosse to Mesa, such as American Airlines. Reviews also offer insight into each airline's entertainment options, comfort, food, crew/service, and boarding process.
American Airlines
7.2
Good
10,000 reviews

Crew

8.0

Boarding

7.5

Entertainment

6.9

Food

6.4

Comfort

7.2

Overall

7.2

Reviews

1 / 20
2.0
Mediocre

Jeremy,Sep 2025

SAN - PHL

Terrible. Bad customer service and unacceptable delay on the tarmac
American Airlines
7.2
Good
10,000 reviews
American Airlines
7.2
Good
10,000 reviews

Crew

8.0

Boarding

7.5

Entertainment

6.9

Food

6.4

Comfort

7.2

Overall

7.2

Reviews

1 / 20
2.0
Mediocre

Jeremy,Sep 2025

SAN - PHL

Terrible. Bad customer service and unacceptable delay on the tarmac

Related info for your journey

Find useful and relevant information for your journey from La Crosse to Mesa. Access travel guides, tips, and recommendations to enhance your travel experience. Get information about local attractions, weather, transportation options, and more.

  • What airport do you fly from for flights from La Crosse to Mesa?

    Most people fly from La Crosse (LSE) if they book a flight from La Crosse to Mesa. On average, La Crosse has 0 outbound flights to Mesa per day from 1 airline. La Crosse is conveniently located just 5.4 mi from La Crosse’s city center.

  • How long is the flight from La Crosse to Mesa?

    For as low as $550, American Airlines can have you in Mesa from La Crosse in 6h 04m. There are 1325 mi between La Crosse and Mesa.

  • Can I find deals for flights from La Crosse to Mesa that include hotel bookings?

    Yes. In addition to deals on La Crosse to Mesa flights, Cheapflights offers vacation packages that include both flights and hotel.

  • How can I find direct flights from La Crosse to Mesa?

    After entering your origin and destination, apply the non-stop filter on the search result page to find direct flights from La Crosse to Mesa.

  • Can I find deals for business class flights from La Crosse to Mesa?

    Yes. Cheapflights offers flight deals from La Crosse to Mesa by cabin class. In addition to browsing deals, you can also filter by cabin class on the search results page after making a search.

  • What is the cheapest month to book a flight from La Crosse to Mesa?

    Currently, January is the cheapest month in which you can book a flight from La Crosse to Mesa (average of $258). Flying from La Crosse to Mesa in March is currently the most expensive (average of $337). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.

See more FAQs

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Top airline flying from La Crosse to Mesa

Discover the top airline that operate flights from La Crosse to Mesa. Compare their services, reliability, and customer satisfaction ratings to choose the airline that best suits your travel preferences and needs. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated September 15, 2025.
AirlineCheapestAverageFlexibilityOn-time
American AirlinesCheapest$500Average$630FlexibilityNo cancel feeOn-time71%

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