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Medellín

$196+ Cheap flights from Missouri to Medellín

This is the cheapest one-way flight price found by a Cheapflights user in the last 72 hours by searching for a flight departing on 5/22. Fares are subject to change and may not be available on all flights or dates of travel.
STL — MDE
May 5 — May 121
Mon 5/5
Mon 5/12
1 adult, Economy
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Cheap flight deals from Missouri to Medellín

Keep the following information in mind while searching for Missouri to Medellín flight deals. Data was last updated April 30, 2025.

Round-trip from

$391
(Kiwi.com)

One-way from

$196
(Kiwi.com)

Popular in

December

Cheapest in

June

Average price

$621
From Missouri to Medellín
Search Deals
One-way flight from Missouri to Medellín
Search Deals
Highest demand for flights based on searches. 6% potential increase in price ($43 potential increase over avg. RT price).
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Cheapest flight prices on average. 2% potential price decrease ($15 potential savings vs. average RT price).
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Average for round-trip flights in April 2025
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Find flight deals from Missouri to Medellín

Cheapest flights from Missouri to Medellín
Explore the most affordable flight options available from Missouri to Medellín. Find the lowest fares from popular airlines and budget airlines, with prices last updated on April 30, 2025.

This Kiwi.com deal was found by Cheapflights users on 4/28. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 5/2510:10 amSTL - MDE
1 stop27h 05mSpirit Airlines
Wed 6/42:13 pmMDE - STL
1 stop19h 02mSpirit Airlines
Deal found 4/28$391
This Orbitz deal was found by Cheapflights users on 4/29. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Orbitz is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 5/295:46 amMCI - MDE
1 stop7h 12mSpirit Airlines
Tue 6/101:53 pmMDE - MCI
1 stop8h 48mSpirit Airlines
Deal found 4/29$417
This Mytrip deal was found by Cheapflights users on 4/28. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Mytrip is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 5/2510:10 amSTL - MDE
2 stops38h 14mMultiple Airlines
Wed 6/49:12 amMDE - STL
2 stops24h 03mMultiple Airlines
Deal found 4/28$418
This Kiwi.com deal was found by Cheapflights users on 4/28. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 5/265:46 amMCI - MDE
1 stop31h 12mMultiple Airlines
Wed 6/117:58 pmMDE - MCI
2 stops38h 12mMultiple Airlines
Deal found 4/28$446
This United Airlines deal was found by Cheapflights users on 4/28. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 8/143:28 pmMCI - MDE
2 stops13h 14mUnited Airlines
Thu 8/289:45 amMDE - MCI
2 stops24h 52mUnited Airlines
Deal found 4/28$594
This American Airlines deal was found by Cheapflights users on 4/28. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 7/235:03 amMCI - MDE
1 stop15h 12mAmerican Airlines
Sat 8/236:00 amMDE - MCI
1 stop18h 29mAmerican Airlines
Deal found 4/28$600
This United Airlines deal was found by Cheapflights users on 4/28. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 6/108:25 amSTL - MDE
1 stop12h 45mUnited Airlines
Fri 7/1112:15 amMDE - STL
1 stop9h 19mUnited Airlines
Deal found 4/28$600
This American Airlines deal was found by Cheapflights users on 4/28. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 7/110:08 amSTL - MDE
2 stops13h 27mAmerican Airlines
Fri 7/412:45 amMDE - STL
2 stops14h 28mAmerican Airlines
Deal found 4/28$653
This Delta deal was found by Cheapflights users on 4/29. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 5/2710:30 amMCI - MDE
2 stops32h 59mDelta
Tue 6/1010:50 amMDE - MCI
2 stops13h 16mDelta
Deal found 4/29$656
This Delta deal was found by Cheapflights users on 4/28. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 5/46:00 amSTL - MDE
2 stops36h 28mDelta
Wed 5/215:31 amMDE - STL
2 stops18h 07mDelta
Deal found 4/28$674
This LATAM Airlines deal was found by Cheapflights users on 4/28. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure LATAM Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 5/57:01 pmSTL - MDE
2 stops26h 16mLATAM Airlines
Fri 5/2311:54 pmMDE - STL
2 stops20h 45mLATAM Airlines
Deal found 4/28$683
This KAYAK deal was found by Cheapflights users on 4/29. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure KAYAK is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 5/267:56 pmMCI - MDE
2 stops25h 21mLATAM Airlines
Sat 6/74:22 amMDE - MCI
2 stops18h 19mLATAM Airlines
Deal found 4/29$686

Cheapflights Fare Finder

Customize your flight search to find flights from Missouri to Medellín that fit within your specific budget. Explore options based on user searches and filter the results based on your desired price range. Find flights that match your budget for a cost-effective journey. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated April 30, 2025.
Use the filters below to find and compare flights from Missouri to Medellín that are best for you.

Fly from

Missouri

Fly to

Medellín

Route

Depart

Return

Price

St. LouisMedellín

STL - MDE

STLMDE

Lambert-St Louis

Sun 5/25

10:10 am-1:15 pm

1 stop27h 05m

Medellín Jose Maria Cordova Intl

Wed 6/4

2:13 pm-9:15 am

1 stop19h 02m

$391

Kansas CityMedellín

MCI - MDE

MCIMDE

Kansas City

Thu 5/29

5:46 am-12:58 pm

1 stop7h 12m

Medellín Jose Maria Cordova Intl

Tue 6/10

1:53 pm-10:41 pm

1 stop8h 48m

$417

St. LouisMedellín

STL - MDE

STLMDE

Lambert-St Louis

Sun 5/25

10:10 am-12:24 am

2 stops38h 14m

Medellín Jose Maria Cordova Intl

Wed 6/4

9:12 am-9:15 am

2 stops24h 03m

$418

Kansas CityMedellín

MCI - MDE

MCIMDE

Kansas City

Mon 5/26

5:46 am-12:58 pm

1 stop31h 12m

Medellín Jose Maria Cordova Intl

Wed 6/11

7:58 pm-10:10 am

2 stops38h 12m

$446

Kansas CityMedellín

MCI - MDE

MCIMDE

Kansas City

Wed 7/23

5:03 am-8:15 pm

1 stop15h 12m

Medellín Jose Maria Cordova Intl

Sat 8/23

6:00 am-12:29 am

1 stop18h 29m

$600

St. LouisMedellín

STL - MDE

STLMDE

Lambert-St Louis

Tue 6/10

8:25 am-9:10 pm

1 stop12h 45m

Medellín Jose Maria Cordova Intl

Fri 7/11

12:15 am-9:34 am

1 stop9h 19m

$600

Kansas CityMedellín

MCI - MDE

MCIMDE

Kansas City

Wed 7/23

8:25 am-9:10 pm

1 stop12h 45m

Medellín Jose Maria Cordova Intl

Sat 8/23

9:45 am-9:09 am

2 stops23h 24m

$604

St. LouisMedellín

STL - MDE

STLMDE

Lambert-St Louis

Tue 7/1

10:08 am-11:35 pm

2 stops13h 27m

Medellín Jose Maria Cordova Intl

Fri 7/4

12:45 am-3:13 pm

2 stops14h 28m

$653

Kansas CityMedellín

MCI - MDE

MCIMDE

Kansas City

Tue 5/27

10:30 am-7:29 pm

2 stops32h 59m

Medellín Jose Maria Cordova Intl

Tue 6/10

10:50 am-12:06 am

2 stops13h 16m

$656

St. LouisMedellín

STL - MDE

STLMDE

Lambert-St Louis

Sun 5/4

6:00 am-6:28 pm

2 stops36h 28m

Medellín Jose Maria Cordova Intl

Wed 5/21

5:31 am-11:38 pm

2 stops18h 07m

$674

Flights are sorted by cheapest round-trip flights first.

Deals found on 4/29

Showing 1-10 of 23 results
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Best time to book a flight from Missouri to Medellín

Have a flexible travel schedule? Discover the best time to fly to Medellín from Missouri with our price prediction graph.
Estimated round-trip price
Rates are based on past data. Find the cheapest month and day to book your flight based on your travel requirements, then search for cheap deals.

Cheapflights Insights

Everything you need to know about your flight from Missouri to Medellín

What is the cheapest month to book a flight from Missouri to Medellín?

Currently, January is the cheapest month in which you can book a flight from Missouri to Medellín (average of $378). Flying from Missouri to Medellín in December is currently the most expensive (average of $625). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.

What is the cheapest time of day to fly from MO to MDE?

Find hourly flight availability from Missouri to Medellín. Discover flight options and departure times throughout the day, allowing you to choose a departure time that suits your schedule. Data last updated April 30, 2025.

Regardless of the time of day you decide to fly, the ticket price will remain around the same. Book flights from Missouri to Medellín as you normally would.

Rainfall in Medellín by month

Plan your trip to Medellín by taking into account the average rainfall totals by month.

In terms of precipitation, rainfall in Medellín ranges from 2.0 - 7.9 inches per month. October is typically the wettest month, when rainfall can reach 7.9 in. January is typically the driest time to visit Medellín when rainfall is around 2.0 in.

Temperature in Medellín by month

Plan your trip to Medellín by taking into account the average temperature totals by month.

If weather is an important factor for your trip to Medellín, use this chart to help with planning. For those seeking warmer temperatures, January is the ideal time of year to visit, when temperatures reach an average of 71.6 F. Travelers looking to avoid the cold should look outside of October, when temperatures are typically at their lowest (around 69.8 F).

Reviews of airlines servicing Medellín

Get insights into the airlines that provide service to Medellín. Read reviews, discover amenities, and learn about the overall travel experience offered by airlines. Use this information to make informed decisions when choosing an airline for your flight to Medellín. Reviews last updated April 30, 2025.
Read reviews from past customers who have flown Delta, LATAM Airlines and Copa Airlines from Missouri to Medellín. In addition to providing an overall rating, users have also rated airlines in terms of entertainment options, comfort, food, crew/service, and boarding process.
Delta
8.0
Very good
7,936 reviews

Comfort

7.9

Food

7.3

Entertainment

7.9

Crew

8.5

Boarding

8.2

Overall

8.0

Reviews

1 / 20
10.0
Excellent

Aaron,Oct 2024

LAX - LHR

This was a flight operated by Virgin Atlantic in their Upper Class cabin. Overall, an outstanding experience.
Delta
8.0
Very good
7,936 reviews
Delta
8.0
Very good
7,936 reviews

Comfort

7.9

Food

7.3

Entertainment

7.9

Crew

8.5

Boarding

8.2

Overall

8.0

Reviews

1 / 20
10.0
Excellent

Aaron,Oct 2024

LAX - LHR

This was a flight operated by Virgin Atlantic in their Upper Class cabin. Overall, an outstanding experience.
LATAM Airlines
7.5
Good
1,767 reviews
Delta
8.0
Very good
7,936 reviews

Comfort

7.9

Food

7.3

Entertainment

7.9

Crew

8.5

Boarding

8.2

Overall

8.0

Reviews

1 / 20
10.0
Excellent

Aaron,Oct 2024

LAX - LHR

This was a flight operated by Virgin Atlantic in their Upper Class cabin. Overall, an outstanding experience.
Copa Airlines
7.5
Good
1,411 reviews
Delta
8.0
Very good
7,936 reviews

Comfort

7.9

Food

7.3

Entertainment

7.9

Crew

8.5

Boarding

8.2

Overall

8.0

Reviews

1 / 20
10.0
Excellent

Aaron,Oct 2024

LAX - LHR

This was a flight operated by Virgin Atlantic in their Upper Class cabin. Overall, an outstanding experience.
United Airlines
7.4
Good
8,696 reviews
Delta
8.0
Very good
7,936 reviews

Comfort

7.9

Food

7.3

Entertainment

7.9

Crew

8.5

Boarding

8.2

Overall

8.0

Reviews

1 / 20
10.0
Excellent

Aaron,Oct 2024

LAX - LHR

This was a flight operated by Virgin Atlantic in their Upper Class cabin. Overall, an outstanding experience.
American Airlines
7.2
Good
10,000 reviews
Delta
8.0
Very good
7,936 reviews

Comfort

7.9

Food

7.3

Entertainment

7.9

Crew

8.5

Boarding

8.2

Overall

8.0

Reviews

1 / 20
10.0
Excellent

Aaron,Oct 2024

LAX - LHR

This was a flight operated by Virgin Atlantic in their Upper Class cabin. Overall, an outstanding experience.

Related info for your journey

Find useful and relevant information for your journey from Missouri to Medellín. Access travel guides, tips, and recommendations to enhance your travel experience. Get information about local attractions, weather, transportation options, and more.

  • What are the cheapest airlines to fly from Missouri to Medellín one-way?

    To fly one-way, consider booking your trip with Spirit Airlines, which is currently one of the cheapest options available, starting at $231. Copa Airlines flights start at $274 while deals on LATAM Airlines start at $337 one-way.

  • What are the most popular routes from Missouri to Medellín?

    Most travelers choose Kansas City - Medellín Jose Maria Cordova Intl, Lambert-St Louis - Medellín Jose Maria Cordova Intl or Springfield-Branson - Medellín Jose Maria Cordova Intl when deciding on the best route from Missouri to Medellín.

  • Can I find deals for flights from Missouri to Medellín that include hotel bookings?

    Yes. In addition to deals on Missouri to Medellín flights, Cheapflights offers vacation packages that include both flights and hotel.

  • How can I find direct flights from Missouri to Medellín?

    After entering your origin and destination, apply the non-stop filter on the search result page to find direct flights from Missouri to Medellín.

  • Can I find deals for business class flights from Missouri to Medellín?

    Yes. Cheapflights offers flight deals from Missouri to Medellín by cabin class. In addition to browsing deals, you can also filter by cabin class on the search results page after making a search.

  • What is the cheapest month to book a flight from Missouri to Medellín?

    Currently, January is the cheapest month in which you can book a flight from Missouri to Medellín (average of $378). Flying from Missouri to Medellín in December is currently the most expensive (average of $625). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.

See more FAQs

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Alternative routes for Missouri to Medellín

See prices for flight routes from nearby airports that may be better suited for you.
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Top 3 airlines flying from Missouri to Medellín

Discover the top 3 airlines that operate flights from Missouri to Medellín. Compare their services, reliability, and customer satisfaction ratings to choose the airline that best suits your travel preferences and needs. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated April 30, 2025.
AirlineCheapestAverageFlexibilityOn-time
Spirit AirlinesCheapest$271Average$423FlexibilityNo cancel feeOn-time65%
United AirlinesCheapest$401Average$613FlexibilityNo cancel feeOn-time69%
American AirlinesCheapest$462Average$720FlexibilityNo cancel feeOn-time71%

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