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Medellín

$135+ Cheap flights from Missouri to Medellín

This is the cheapest one-way flight price found by a Cheapflights user in the last 72 hours by searching for a flight departing on 1/18. Fares are subject to change and may not be available on all flights or dates of travel.
MCI — MDE
Jan 17 — Jan 241
Sat 1/17
Sat 1/24
1 adult, Economy
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Cheap flight deals from Missouri to Medellín

Cheapest flights from Missouri to Medellín
Explore the most affordable flight options available from Missouri to Medellín. Find the lowest fares from popular airlines and budget airlines, with prices last updated on December 18, 2025.

This Kiwi.com deal was found by Cheapflights users on 12/17. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 12/246:15 pmMCI - MDE
1 stop26h 25mMultiple Airlines
Tue 12/302:25 amMDE - MCI
1 stop15h 45mMultiple Airlines
Deal found 12/17$495
This KAYAK deal was found by Cheapflights users on 12/16. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure KAYAK is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 12/263:47 pmMCI - MDE
1 stop18h 08mSpirit Airlines
Tue 12/302:25 amMDE - MCI
1 stop15h 45mSpirit Airlines
Deal found 12/16$614
This KAYAK deal was found by Cheapflights users on 12/17. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure KAYAK is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 12/246:15 pmMCI - MDE
2 stops18h 42mSpirit Airlines
Tue 12/302:25 amMDE - MCI
2 stops21h 34mSpirit Airlines
Deal found 12/17$622
This KAYAK deal was found by Cheapflights users on 12/16. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure KAYAK is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 12/1811:51 amSTL - MDE
2 stops22h 04mSpirit Airlines
Sat 12/202:25 amMDE - STL
1 stop9h 31mSpirit Airlines
Deal found 12/16$711
This American Airlines deal was found by Cheapflights users on 12/16. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 12/285:40 amSTL - MDE
2 stops14h 30mAmerican Airlines
Thu 1/297:00 amMDE - STL
2 stops17h 12mAmerican Airlines
Deal found 12/16$791
This Mytrip deal was found by Cheapflights users on 12/16. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Mytrip is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 12/189:50 amSTL - MDE
3 stops24h 05mMultiple Airlines
Sat 12/202:25 amMDE - STL
1 stop9h 31mMultiple Airlines
Deal found 12/16$813
This Kiwi.com deal was found by Cheapflights users on 12/18. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 12/2210:40 amSTL - MDE
1 stop23h 15mMultiple Airlines
Wed 1/72:54 pmMDE - STL
1 stop8h 39mMultiple Airlines
Deal found 12/18$816
This Copa Airlines deal was found by Cheapflights users on 12/17. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Copa Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 12/288:05 amSTL - MDE
2 stops23h 13mCopa Airlines
Thu 1/295:00 amMDE - STL
2 stops15h 27mCopa Airlines
Deal found 12/17$823
This United Airlines deal was found by Cheapflights users on 12/16. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 12/286:00 amSTL - MDE
1 stop15h 05mUnited Airlines
Thu 1/2910:45 amMDE - STL
1 stop12h 15mUnited Airlines
Deal found 12/16$911
This United Airlines deal was found by Cheapflights users on 12/18. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 12/225:02 pmSTL - MDE
2 stops11h 40mUnited Airlines
Wed 1/710:45 amMDE - STL
2 stops26h 44mUnited Airlines
Deal found 12/18$1,262
This United Airlines deal was found by Cheapflights users on 12/17. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 12/203:00 pmSGF - MDE
1 stop30h 05mUnited Airlines
Fri 1/210:45 amMDE - SGF
1 stop8h 42mUnited Airlines
Deal found 12/17$1,368

Find flight deals from Missouri to Medellín

Keep the following information in mind while searching for Missouri to Medellín flight deals. Data was last updated December 18, 2025.

Round-trip from

$332
(Kiwi.com)

One-way from

$135
(Kiwi.com)

Popular in

December

Cheapest in

April

Average price

$950
From Missouri to Medellín
Search Deals
One-way flight from Missouri to Medellín
Search Deals
Highest demand for flights based on searches. 9% potential increase in price ($77 potential increase over avg. RT price).
Search Deals
Cheapest flight prices on average. 3% potential price decrease ($25 potential savings vs. average RT price).
Search Deals
Average for round-trip flights in December 2025
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Cheapflights Fare Finder

 
Customize your flight search to find flights from Missouri to Medellín that fit within your specific budget. Explore options based on user searches and filter the results based on your desired price range. Find flights that match your budget for a cost-effective journey. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated December 18, 2025.
Use the filters below to find and compare flights from Missouri to Medellín that are best for you.

Fly from

Missouri

Fly to

Medellín

Route

Depart

Return

Price

St. LouisMedellín

STL - MDE

STLMDE

Lambert-St Louis

Sat 1/31

8:22 pm-1:55 pm

2 stops16h 33m

Medellín Jose Maria Cordova Intl

Sat 2/7

2:50 pm-11:33 pm

1 stop9h 43m

$370

Kansas CityMedellín

MCI - MDE

MCIMDE

Kansas City

Mon 1/5

6:15 pm-2:14 pm

1 stop18h 59m

Medellín Jose Maria Cordova Intl

Fri 1/16

3:15 pm-4:09 pm

2 stops25h 54m

$435

Kansas CityMedellín

MCI - MDE

MCIMDE

Kansas City

Tue 1/13

5:04 pm-1:55 pm

1 stop19h 51m

Medellín Jose Maria Cordova Intl

Tue 1/20

2:50 pm-4:09 pm

1 stop26h 19m

$449

Kansas CityMedellín

MCI - MDE

MCIMDE

Kansas City

Wed 1/7

6:15 pm-2:15 pm

1 stop19h 00m

Medellín Jose Maria Cordova Intl

Sat 1/17

3:15 pm-10:31 am

1 stop20h 16m

$455

Kansas CityMedellín

MCI - MDE

MCIMDE

Kansas City

Sun 1/11

11:26 am-9:40 pm

1 stop9h 14m

Medellín Jose Maria Cordova Intl

Thu 1/15

6:00 am-10:31 am

2 stops29h 31m

$464

St. LouisMedellín

STL - MDE

STLMDE

Lambert-St Louis

Sat 1/31

8:30 am-11:15 pm

2 stops13h 45m

Medellín Jose Maria Cordova Intl

Sat 2/7

8:10 pm-10:13 am

2 stops15h 03m

$468

Kansas CityMedellín

MCI - MDE

MCIMDE

Kansas City

Fri 1/9

11:26 am-1:55 pm

2 stops25h 29m

Medellín Jose Maria Cordova Intl

Fri 1/16

3:15 pm-4:09 pm

2 stops25h 54m

$486

Kansas CityMedellín

MCI - MDE

MCIMDE

Kansas City

Mon 1/5

6:15 pm-1:57 pm

2 stops18h 42m

Medellín Jose Maria Cordova Intl

Thu 1/15

2:50 pm-10:31 am

2 stops20h 41m

$504

Kansas CityMedellín

MCI - MDE

MCIMDE

Kansas City

Thu 1/8

5:04 pm-2:15 pm

2 stops20h 11m

Medellín Jose Maria Cordova Intl

Thu 1/15

3:15 pm-4:09 pm

2 stops25h 54m

$512

SpringfieldMedellín

SGF - MDE

SGFMDE

Springfield-Branson

Mon 2/23

9:00 am-10:05 pm

1 stop12h 05m

Medellín Jose Maria Cordova Intl

Wed 2/25

10:45 am-10:05 pm

1 stop12h 20m

$523

Flights are sorted by cheapest round-trip flights first.

Deals found on 12/17

Showing 1-10 of 23 results
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Best time to book a flight from Missouri to Medellín

Have a flexible travel schedule? Discover the best time to fly to Medellín from Missouri with our price prediction graph.
Estimated round-trip price
Rates are based on past data. Find the cheapest month and day to book your flight based on your travel requirements, then search for cheap deals.

Cheapflights Insights

Everything you need to know about your flight from Missouri to Medellín

What is the cheapest month to book a flight from Missouri to Medellín?

Currently, October is the cheapest month in which you can book a flight from Missouri to Medellín (average of $303). Flying from Missouri to Medellín in December is currently the most expensive (average of $600). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.

What is the cheapest time of day to fly from MO to MDE?

Find hourly flight availability from Missouri to Medellín. Discover flight options and departure times throughout the day, allowing you to choose a departure time that suits your schedule. Data last updated December 18, 2025.

It’s optimal to fly from Missouri to Medellín in the afternoon. By choosing this option you can save up to 36% on the cost of your flight, compared to a flight in the morning.

How much does it cost to fly round-trip from Missouri to Medellín?

Related info for your journey

Find useful and relevant information for your journey from Missouri to Medellín. Access travel guides, tips, and recommendations to enhance your travel experience. Get information about local attractions, weather, transportation options, and more.

  • How long is the flight from Missouri to Medellín?

    Spirit Airlines, Avianca, and United Airlines can get you from Missouri to Medellín in just under 12h 05m. Your travel time can differ by up to 6h 54m. The distance between Missouri and Medellín is about 2425 mi. This flight may include one or multiple stops.

  • What are the most popular routes from Missouri to Medellín?

    Most travelers choose Lambert-St Louis - Medellín Jose Maria Cordova Intl, Kansas City - Medellín Jose Maria Cordova Intl or Springfield-Branson - Medellín Jose Maria Cordova Intl when deciding on the best route from Missouri to Medellín.

  • Can I find deals for flights from Missouri to Medellín that include hotel bookings?

    Yes. In addition to deals on Missouri to Medellín flights, Cheapflights offers vacation packages that include both flights and hotel.

  • How can I find direct flights from Missouri to Medellín?

    After entering your origin and destination, apply the non-stop filter on the search result page to find direct flights from Missouri to Medellín.

  • Can I find deals for business class flights from Missouri to Medellín?

    Yes. Cheapflights offers flight deals from Missouri to Medellín by cabin class. In addition to browsing deals, you can also filter by cabin class on the search results page after making a search.

  • What is the cheapest month to book a flight from Missouri to Medellín?

    Currently, October is the cheapest month in which you can book a flight from Missouri to Medellín (average of $303). Flying from Missouri to Medellín in December is currently the most expensive (average of $600). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.

See more FAQs

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Alternative routes for Missouri to Medellín

See prices for flight routes from nearby airports that may be better suited for you.
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Top 3 airlines flying from Missouri to Medellín

Discover the top 3 airlines that operate flights from Missouri to Medellín. Compare their services, reliability, and customer satisfaction ratings to choose the airline that best suits your travel preferences and needs. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated December 18, 2025.
AirlineCheapestAverageFlexibilityOn-time
Spirit AirlinesCheapest$303Average$381FlexibilityNo cancel feeOn-time65%
United AirlinesCheapest$507Average$639FlexibilityNo cancel feeOn-time69%
American AirlinesCheapest$565Average$803FlexibilityNo cancel feeOn-time71%

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