HomeSearch by dateVacation packagesHotelsFlight dealsCar rentalTravel tips & news
Medellín

$211+ Cheap flights from Missouri to Medellín

This is the cheapest one-way flight price found by a Cheapflights user in the last 72 hours by searching for a flight departing on 11/29. Fares are subject to change and may not be available on all flights or dates of travel.
STL — MDE
Nov 29 — Dec 61
Sat 11/29
Sat 12/6
1 adult, Economy
We work with more than 300 partners to bring you better travel deals

Find cheap flights from Missouri to Medellín with Cheapflights

1. Tell us where you want to go

Enter your travel information like dates, passengers, trip type (one-way or round trip), and preferred cabin class then click “Find deals”

2. Select your favorite providers

We find the providers serving your travel needs. Choose up to four travel providers to compare side-by-side for flights, hotels, or car rentals.

3. Compare prices and book

Review each provider’s pricing and select the best option for you! Book through your favorite provider’s website for a seamless experience.

Find flight deals from Missouri to Medellín

Cheapest flights from Missouri to Medellín
Explore the most affordable flight options available from Missouri to Medellín. Find the lowest fares from popular airlines and budget airlines, with prices last updated on October 30, 2025.

This CheapOair deal was found by Cheapflights users on 10/30. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure CheapOair is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 12/73:47 pmMCI - MDE
1 stop18h 08mSpirit Airlines
Sun 12/142:05 amMDE - MCI
1 stop16h 51mSpirit Airlines
Deal found 10/30$316
This Expedia deal was found by Cheapflights users on 10/30. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Expedia is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 12/43:47 pmMCI - MDE
1 stop18h 08mSpirit Airlines
Sun 12/72:05 amMDE - MCI
1 stop16h 51mSpirit Airlines
Deal found 10/30$373
This Orbitz deal was found by Cheapflights users on 10/30. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Orbitz is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 11/247:31 pmMCI - MDE
1 stop17h 32mSpirit Airlines
Fri 11/281:51 amMDE - MCI
1 stop14h 28mSpirit Airlines
Deal found 10/30$409
This Kiwi.com deal was found by Cheapflights users on 10/29. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 12/113:30 pmSTL - MDE
1 stop18h 25mMultiple Airlines
Sun 12/142:54 pmMDE - STL
1 stop19h 05mMultiple Airlines
Deal found 10/29$418
This CheapOair deal was found by Cheapflights users on 10/28. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure CheapOair is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 12/2811:51 amSTL - MDE
1 stop12h 37mSpirit Airlines
Wed 1/281:51 amMDE - STL
1 stop10h 10mSpirit Airlines
Deal found 10/28$447
This Priceline deal was found by Cheapflights users on 10/30. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Priceline is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 11/37:33 pmMCI - MDE
1 stop17h 30mSpirit Airlines
Thu 11/203:14 pmMDE - MCI
2 stops21h 49mSpirit Airlines
Deal found 10/30$467
This Kiwi.com deal was found by Cheapflights users on 10/28. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 11/144:56 pmSTL - MDE
2 stops15h 04mMultiple Airlines
Wed 11/191:00 pmMDE - STL
1 stop21h 58mMultiple Airlines
Deal found 10/28$470
This CheapOair deal was found by Cheapflights users on 10/28. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure CheapOair is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 11/67:02 pmSTL - MDE
1 stop18h 01mSpirit Airlines
Sat 11/81:52 amMDE - STL
1 stop16h 24mSpirit Airlines
Deal found 10/28$517
This CheapOair deal was found by Cheapflights users on 10/30. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure CheapOair is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 12/112:47 pmSTL - MDE
1 stop9h 22mSpirit Airlines
Sat 12/132:05 amMDE - STL
1 stop12h 47mSpirit Airlines
Deal found 10/30$566
This Kiwi.com deal was found by Cheapflights users on 10/28. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 11/244:13 pmSTL - MDE
2 stops23h 28mMultiple Airlines
Fri 11/281:51 amMDE - STL
1 stop8h 06mMultiple Airlines
Deal found 10/28$574
This Kiwi.com deal was found by Cheapflights users on 10/29. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 12/23:30 pmSTL - MDE
1 stop21h 31mMultiple Airlines
Tue 12/92:54 pmMDE - STL
1 stop8h 39mMultiple Airlines
Deal found 10/29$576
This United Airlines deal was found by Cheapflights users on 10/28. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 12/286:00 amSTL - MDE
1 stop22h 42mUnited Airlines
Thu 1/2910:45 amMDE - STL
1 stop12h 15mUnited Airlines
Deal found 10/28$585

Cheap flight deals from Missouri to Medellín

Keep the following information in mind while searching for Missouri to Medellín flight deals. Data was last updated October 30, 2025.

Round-trip from

$295
(Kiwi.com)

One-way from

$211
(CheapOair)

Popular in

December

Cheapest in

April

Average price

$663
From Missouri to Medellín
Search Deals
One-way flight from Missouri to Medellín
Search Deals
Highest demand for flights based on searches. 10% potential increase in price ($81 potential increase over avg. RT price).
Search Deals
Cheapest flight prices on average. 3% potential price decrease ($24 potential savings vs. average RT price).
Search Deals
Average for round-trip flights in October 2025
Search Deals

Cheapflights Fare Finder

 
Customize your flight search to find flights from Missouri to Medellín that fit within your specific budget. Explore options based on user searches and filter the results based on your desired price range. Find flights that match your budget for a cost-effective journey. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated October 30, 2025.
Use the filters below to find and compare flights from Missouri to Medellín that are best for you.

Fly from

Missouri

Fly to

Medellín

Route

Depart

Return

Price

Kansas CityMedellín

MCI - MDE

MCIMDE

Kansas City

Sun 12/7

3:47 pm-10:55 am

1 stop18h 08m

Medellín Jose Maria Cordova Intl

Sun 12/14

2:05 am-5:56 pm

1 stop16h 51m

$316

St. LouisMedellín

STL - MDE

STLMDE

Lambert-St Louis

Sun 1/11

12:20 pm-1:55 pm

2 stops24h 35m

Medellín Jose Maria Cordova Intl

Wed 1/21

12:09 pm-10:33 pm

1 stop11h 24m

$364

Kansas CityMedellín

MCI - MDE

MCIMDE

Kansas City

Thu 12/4

3:47 pm-10:55 am

1 stop18h 08m

Medellín Jose Maria Cordova Intl

Sun 12/7

2:05 am-5:56 pm

1 stop16h 51m

$373

St. LouisMedellín

STL - MDE

STLMDE

Lambert-St Louis

Sat 1/10

5:11 pm-11:03 am

1 stop16h 52m

Medellín Jose Maria Cordova Intl

Thu 1/22

12:09 pm-10:33 pm

1 stop11h 24m

$390

St. LouisMedellín

STL - MDE

STLMDE

Lambert-St Louis

Sat 1/10

2:48 pm-12:56 am

1 stop9h 08m

Medellín Jose Maria Cordova Intl

Tue 1/20

10:45 pm-10:33 pm

2 stops24h 48m

$407

Kansas CityMedellín

MCI - MDE

MCIMDE

Kansas City

Mon 11/24

7:31 pm-2:03 pm

1 stop17h 32m

Medellín Jose Maria Cordova Intl

Fri 11/28

1:51 am-3:19 pm

1 stop14h 28m

$409

St. LouisMedellín

STL - MDE

STLMDE

Lambert-St Louis

Thu 12/11

2:47 pm-1:09 am

1 stop9h 22m

Medellín Jose Maria Cordova Intl

Sun 12/14

3:10 pm-9:52 am

2 stops19h 42m

$431

St. LouisMedellín

STL - MDE

STLMDE

Lambert-St Louis

Sun 1/11

12:20 pm-2:16 pm

1 stop24h 56m

Medellín Jose Maria Cordova Intl

Fri 1/16

6:35 am-10:37 pm

1 stop17h 02m

$438

St. LouisMedellín

STL - MDE

STLMDE

Lambert-St Louis

Sun 12/28

11:51 am-1:28 am

1 stop12h 37m

Medellín Jose Maria Cordova Intl

Wed 1/28

1:51 am-11:01 am

1 stop10h 10m

$447

St. LouisMedellín

STL - MDE

STLMDE

Lambert-St Louis

Fri 11/14

4:56 pm-9:00 am

2 stops15h 04m

Medellín Jose Maria Cordova Intl

Wed 11/19

1:00 pm-9:58 am

1 stop21h 58m

$470

Flights are sorted by cheapest round-trip flights first.

Deals found on 10/30

Showing 1-10 of 24 results
1
2
3

Best time to book a flight from Missouri to Medellín

Have a flexible travel schedule? Discover the best time to fly to Medellín from Missouri with our price prediction graph.
Estimated round-trip price
Rates are based on past data. Find the cheapest month and day to book your flight based on your travel requirements, then search for cheap deals.

Cheapflights Insights

Everything you need to know about your flight from Missouri to Medellín

What is the cheapest month to book a flight from Missouri to Medellín?

Currently, October is the cheapest month in which you can book a flight from Missouri to Medellín (average of $303). Flying from Missouri to Medellín in March is currently the most expensive (average of $571). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.

What is the cheapest time of day to fly from MO to MDE?

Find hourly flight availability from Missouri to Medellín. Discover flight options and departure times throughout the day, allowing you to choose a departure time that suits your schedule. Data last updated October 30, 2025.

It’s optimal to fly from Missouri to Medellín in the afternoon. By choosing this option you can save up to 28% on the cost of your flight, compared to a flight in the morning.

Related info for your journey

Find useful and relevant information for your journey from Missouri to Medellín. Access travel guides, tips, and recommendations to enhance your travel experience. Get information about local attractions, weather, transportation options, and more.

  • How long is the flight from Missouri to Medellín?

    Spirit Airlines and United Airlines can get you from Missouri to Medellín in just under 12h 20m. Your travel time can differ by up to 5h 48m. The distance between Missouri and Medellín is about 2425 mi. This flight may include one or multiple stops.

  • What are the cheapest airlines to fly from Missouri to Medellín one-way?

    To fly one-way, consider booking your trip with Spirit Airlines, which is currently one of the cheapest options available, starting at $215. United Airlines flights start at $400 while deals on American Airlines start at $403 one-way.

  • What are the most popular routes from Missouri to Medellín?

    Most travelers choose Lambert-St Louis - Medellín Jose Maria Cordova Intl, Kansas City - Medellín Jose Maria Cordova Intl or Springfield-Branson - Medellín Jose Maria Cordova Intl when deciding on the best route from Missouri to Medellín.

  • Can I find deals for flights from Missouri to Medellín that include hotel bookings?

    Yes. In addition to deals on Missouri to Medellín flights, Cheapflights offers vacation packages that include both flights and hotel.

  • How can I find direct flights from Missouri to Medellín?

    After entering your origin and destination, apply the non-stop filter on the search result page to find direct flights from Missouri to Medellín.

  • Can I find deals for business class flights from Missouri to Medellín?

    Yes. Cheapflights offers flight deals from Missouri to Medellín by cabin class. In addition to browsing deals, you can also filter by cabin class on the search results page after making a search.

  • What is the cheapest month to book a flight from Missouri to Medellín?

    Currently, October is the cheapest month in which you can book a flight from Missouri to Medellín (average of $303). Flying from Missouri to Medellín in March is currently the most expensive (average of $571). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.

See more FAQs

Browse thousands of different options on Cheapflights for your next trip

Toggle through the tabs below to find thousands of options on Cheapflights for your next trip.

Alternative routes for Missouri to Medellín

See prices for flight routes from nearby airports that may be better suited for you.
Miami to Jose Maria Cordova Intl flights
John F Kennedy Intl to Jose Maria Cordova Intl flights
Fort Lauderdale to Jose Maria Cordova Intl flights
John F Kennedy Intl to Cartagena flights
John F Kennedy Intl to Bogotá flights
Newark to Jose Maria Cordova Intl flights
LaGuardia to Jose Maria Cordova Intl flights
Newark to Bogotá flights
Dulles Intl to Jose Maria Cordova Intl flights
Fort Lauderdale to Bogotá flights
Miami to Bogotá flights
Orlando to Jose Maria Cordova Intl flights
Hobby to Jose Maria Cordova Intl flights
Dallas/Fort Worth to Jose Maria Cordova Intl flights
Boston to Jose Maria Cordova Intl flights
John F Kennedy Intl to Cali flights
Miami to Cartagena flights
Dulles Intl to Bogotá flights
George Bush Intcntl to Jose Maria Cordova Intl flights
Reagan-National to Jose Maria Cordova Intl flights
Baltimore to Jose Maria Cordova Intl flights
Miami to Cali flights
John F Kennedy Intl to Enrique Olaya flights
Miami to Enrique Olaya flights
Miami to Barranquilla flights
LaGuardia to Cartagena flights
O'Hare Intl to Jose Maria Cordova Intl flights
LaGuardia to Bogotá flights
Newark to Cartagena flights
Los Angeles to Jose Maria Cordova Intl flights
Atlanta to Bogotá flights
Fort Lauderdale to Cartagena flights
Newark to Cali flights
Hobby to Bogotá flights
LaGuardia to Cali flights
Orlando to Bogotá flights
Fort Lauderdale to Cali flights
Los Angeles to Bogotá flights
Dulles Intl to Cartagena flights
Atlanta to Jose Maria Cordova Intl flights
George Bush Intcntl to Bogotá flights
San Francisco to Jose Maria Cordova Intl flights
Tampa to Jose Maria Cordova Intl flights
Reagan-National to Bogotá flights
Baltimore to Bogotá flights
San Francisco to Bogotá flights
Fort Lauderdale to Enrique Olaya flights
Miami to Pereira flights
Orlando to Enrique Olaya flights
Reagan-National to Cartagena flights

Top 3 airlines flying from Missouri to Medellín

Discover the top 3 airlines that operate flights from Missouri to Medellín. Compare their services, reliability, and customer satisfaction ratings to choose the airline that best suits your travel preferences and needs. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated October 30, 2025.
AirlineCheapestAverageFlexibilityOn-time
Spirit AirlinesCheapest$303Average$386FlexibilityNo cancel feeOn-time65%
United AirlinesCheapest$441Average$631FlexibilityNo cancel feeOn-time69%
American AirlinesCheapest$565Average$794FlexibilityNo cancel feeOn-time71%

100% Free

Cheapflights is completely free to use, so you can start saving the moment you arrive.

Book with Flexibility

Our users can plan ahead with confidence and find flights with no change fees

Travel Smart

Millions of people come to us for their flight needs every year. We help make travel planning easy by providing useful insights and data-driven graphs that can inform your decisions.