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$217+ Cheap flights from Greenville (GSP) to Medellín

This is the cheapest one-way flight price found by a Cheapflights user in the last 72 hours by searching for a flight departing on 6/22. Fares are subject to change and may not be available on all flights or dates of travel.
GSP — MDE
May 28 — Jun 41
Thu 5/28
Thu 6/4
1 adult, Economy
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Cheap flight deals from Greenville to Medellín

Cheapest flights from Greenville to Medellín
Explore the most affordable flight options available from Greenville to Medellín. Find the lowest fares from popular airlines and budget airlines, with prices last updated on April 28, 2026.

This American Airlines deal was found by Cheapflights users on 4/24. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 8/106:00 am
GSP
-
MDE
1 stop15h 15m
American Airlines
Sun 8/1612:30 am
MDE
-
GSP
1 stop16h 40m
American Airlines
Deal found 4/24$560
This American Airlines deal was found by Cheapflights users on 4/25. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 8/27:43 pm
GSP
-
MDE
1 stop18h 06m
American Airlines
Mon 8/176:00 am
MDE
-
GSP
1 stop11h 10m
American Airlines
Deal found 4/25$574
This American Airlines deal was found by Cheapflights users on 4/23. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 7/308:00 pm
GSP
-
MDE
1 stop17h 51m
American Airlines
Mon 8/176:00 am
MDE
-
GSP
1 stop11h 10m
American Airlines
Deal found 4/23$582
This American Airlines deal was found by Cheapflights users on 4/25. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 10/256:21 am
GSP
-
MDE
2 stops14h 34m
American Airlines
Sat 10/315:45 am
MDE
-
GSP
2 stops12h 17m
American Airlines
Deal found 4/25$589
This American Airlines deal was found by Cheapflights users on 4/23. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 6/128:15 pm
GSP
-
MDE
1 stop17h 36m
American Airlines
Fri 6/191:53 pm
MDE
-
GSP
1 stop20h 49m
American Airlines
Deal found 4/23$601
This Kiwi.com deal was found by Cheapflights users on 4/27. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 6/112:04 pm
GSP
-
MDE
2 stops47h 59m
Multiple Airlines
Thu 6/182:26 pm
MDE
-
GSP
1 stop29h 35m
Multiple Airlines
Deal found 4/27$610
This KAYAK deal was found by Cheapflights users on 4/25. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure KAYAK is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 8/27:40 pm
GSP
-
MDE
2 stops26h 30m
Multiple Airlines
Mon 8/179:45 am
MDE
-
GSP
2 stops22h 58m
Multiple Airlines
Deal found 4/25$615
This American Airlines deal was found by Cheapflights users on 4/27. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 7/2910:45 am
GSP
-
MDE
2 stops14h 03m
American Airlines
Tue 8/1112:30 am
MDE
-
GSP
1 stop16h 40m
American Airlines
Deal found 4/27$618

Find flight deals from Greenville to Medellín

Discover tips and strategies to find the most affordable flight options for your journey from Greenville (GSP) to Medellín (CO1). Learn about various techniques such as flexible date searches, comparing prices across and setting up price alerts. Use these methods to find the cheapest flights available for your travel needs. Data last updated April 28, 2026.

Round-trip from

$560
(American Airlines)

One-way from

$217
(Kiwi.com)

Popular in

October

Cheapest in

August

Average price

$883
From Greenville to Medellín
Search Deals
One-way flight from Greenville to Medellín
Search Deals
Highest demand for flights based on searches. 7% potential increase in price ($64 potential increase over avg. RT price).
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Cheapest flight prices on average. 1% potential price decrease ($13 potential savings vs. average RT price).
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Average for round-trip flights in April 2026
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Cheapflights Fare Finder

 
Customize your flight search to find flights from Greenville to Medellín that fit within your specific budget. Explore options based on user searches and filter the results based on your desired price range. Find flights that match your budget for a cost-effective journey. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated April 28, 2026.
Use the filters below to find and compare flights from Greenville to Medellín that are best for you.

Fly from

Fly to

Route

Depart

Return

Price

Cheapest round-trip

GreenvilleMedellín

GSP - MDE

GSPMDE

Greenville

Thu 7/30

8:00 pm-12:51 pm

1 stop17h 51m

Medellín Jose Maria Cordova Intl

Mon 8/17

6:00 am-6:10 pm

1 stop11h 10m

$582
Quickest round-trip

GreenvilleMedellín

GSP - MDE

GSPMDE

Greenville

Sun 10/25

5:52 am-12:35 pm

1 stop7h 43m

Medellín Jose Maria Cordova Intl

Sat 10/31

5:45 am-3:26 pm

1 stop8h 41m

$584

GreenvilleMedellín

GSP - MDE

GSPMDE

Greenville

Mon 8/24

7:00 am-9:10 pm

1 stop15h 10m

Medellín Jose Maria Cordova Intl

Thu 8/27

9:45 am-9:53 pm

1 stop11h 08m

$624

GreenvilleMedellín

GSP - MDE

GSPMDE

Greenville

Wed 7/29

6:00 am-11:48 pm

1 stop18h 48m

Medellín Jose Maria Cordova Intl

Wed 8/12

6:00 am-6:10 pm

1 stop11h 10m

$625
Cheapest one-way

GreenvilleMedellín

GSP - MDE

GSPMDE

Greenville

Mon 6/22

8:29 am-8:15 am

2 stops24h 46m

$217

GreenvilleMedellín

GSP - MDE

GSPMDE

Greenville

Thu 5/14

3:28 pm-8:15 am

3 stops41h 47m

$246

GreenvilleMedellín

GSP - MDE

GSPMDE

Greenville

Fri 5/15

5:43 pm-8:15 am

3 stops39h 32m

$247

GreenvilleMedellín

GSP - MDE

GSPMDE

Greenville

Mon 10/5

8:32 pm-2:15 pm

2 stops18h 43m

$252

GreenvilleMedellín

GSP - MDE

GSPMDE

Greenville

Mon 10/5

5:52 am-7:55 pm

1 stop15h 03m

$335

GreenvilleMedellín

GSP - MDE

GSPMDE

Greenville

Thu 5/14

6:00 am-8:15 pm

1 stop15h 15m

$386

Flights are sorted by cheapest round-trip flights first.

Deals found on 4/26

Showing 1-10 of 12 resultsSorted by cheapest first
1
2

Best time to book a flight from Greenville to Medellín

Have a flexible travel schedule? Discover the best time to fly to Medellín from Greenville with our price prediction graph.
Estimated round-trip price
Rates are based on past data. Find the cheapest month and day to book your flight based on your travel requirements, then search for cheap deals.

Cheapflights Insights

Everything you need to know about your flight from Greenville to Medellín

How far ahead should I book a flight from Greenville to Medellín?

The best time to book flights from Greenville to Medellín is 39 days before your desired departure date. The cost of your flight will likely increase significantly if you book two weeks in advance of your flight.

What is the cheapest month to book a flight from Greenville to Medellín?

Currently, April is the cheapest month in which you can book a flight from Greenville to Medellín (average of $81). Flying from Greenville to Medellín in January is currently the most expensive (average of $660). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.

How much does it cost to fly round-trip from Greenville to Medellín?

Reviews of airlines servicing Medellín

Get insights into the airlines that provide service to Medellín. Read reviews, discover amenities, and learn about the overall travel experience offered by airlines. Use this information to make informed decisions when choosing an airline for your flight to Medellín. Reviews last updated April 28, 2026.
Get a feel of what it's like to fly with American Airlines from Greenville to Medellín by reading reviews from past customers. Users have also rated airlines in terms of entertainment options, comfort, food, crew/service, and boarding process.
American Airlines
7.1
Good
11,674 reviews

Crew

7.9

Entertainment

6.9

Overall

7.1

Food

6.4

Comfort

7.2

Boarding

7.5

Reviews

1 / 20
2.0
Mediocre

Anonymous,Apr 2026

DFW - BDL

They keep changing the gate, delaying the hours and then finally canceled it. No accomodation, no food, nothing!
American Airlines
7.1
Good
11,674 reviews
American Airlines
7.1
Good
11,674 reviews

Crew

7.9

Entertainment

6.9

Overall

7.1

Food

6.4

Comfort

7.2

Boarding

7.5

Reviews

1 / 20
2.0
Mediocre

Anonymous,Apr 2026

DFW - BDL

They keep changing the gate, delaying the hours and then finally canceled it. No accomodation, no food, nothing!

Related info for your journey

Find useful and relevant information for your journey from Greenville to Medellín. Access travel guides, tips, and recommendations to enhance your travel experience. Get information about local attractions, weather, transportation options, and more.

  • What airport do you fly from for flights from Greenville to Medellín?

    If you book a flight to Medellín from Greenville, you will be flying from Greenville, which is the city’s only airport. Greenville (GSP) is located 10.4 mi from the center of Greenville. There are 0 flights from Greenville to Medellín per day from 1 airline.

  • How long is the flight from Greenville to Medellín?

    American Airlines and United Airlines can get you from Greenville to Medellín in just under 15h 10m. Your travel time can differ by up to 2h 41m. Airlines will cover a distance of 2030 mi. This flight may include one or multiple stops.

  • What is the cheapest airline to fly from Greenville to Medellín round-trip?

    American Airlines, at $515, was found to be the cheapest airline from Greenville to Medellín.. Users have found that American Airlines is 33% cheaper than the other options available to this destination.

  • Can I find deals for flights from Greenville to Medellín that include hotel bookings?

    Yes. In addition to deals on Greenville to Medellín flights, Cheapflights offers vacation packages that include both flights and hotel.

  • How can I find direct flights from Greenville to Medellín?

    After entering your origin and destination, apply the non-stop filter on the search result page to find direct flights from Greenville to Medellín.

  • Can I find deals for business class flights from Greenville to Medellín?

    Yes. Cheapflights offers flight deals from Greenville to Medellín by cabin class. In addition to browsing deals, you can also filter by cabin class on the search results page after making a search.

  • What is the cheapest month to book a flight from Greenville to Medellín?

    Currently, April is the cheapest month in which you can book a flight from Greenville to Medellín (average of $81). Flying from Greenville to Medellín in January is currently the most expensive (average of $660). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.

See more FAQs

Browse thousands of different options on Cheapflights for your next trip

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Top airline flying from Greenville to Medellín

Discover the top airline that operate flights from Greenville to Medellín. Compare their services, reliability, and customer satisfaction ratings to choose the airline that best suits your travel preferences and needs. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated April 28, 2026.
AirlineCheapestAverageFlexibilityOn-time
American AirlinesCheapest$515Average$747FlexibilityNo cancel feeOn-time71%

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