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Medellín

$203+ Cheap flights from Greenville (GSP) to Medellín

This is the cheapest one-way flight price found by a Cheapflights user in the last 72 hours by searching for a flight departing on 9/6. Fares are subject to change and may not be available on all flights or dates of travel.
GSP — MDE
Aug 26 — Sep 21
Wed 8/26
Wed 9/2
1 adult, Economy
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Cheap flight deals from Greenville to Medellín

Cheapest flights from Greenville to Medellín
Explore the most affordable flight options available from Greenville to Medellín. Find the lowest fares from popular airlines and budget airlines, with prices last updated on July 27, 2026.

This United Airlines deal was found by Cheapflights users on 7/23. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 10/236:20 am
GSP
-
MDE
2 stops15h 50m
United Airlines
Mon 11/2310:40 am
MDE
-
GSP
2 stops23h 11m
United Airlines
Deal found 7/23$590
This United Airlines deal was found by Cheapflights users on 7/26. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 9/96:10 pm
GSP
-
MDE
2 stops28h 00m
United Airlines
Wed 9/169:45 am
MDE
-
GSP
1 stop11h 13m
United Airlines
Deal found 7/26$605
This United Airlines deal was found by Cheapflights users on 7/23. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 10/316:30 am
GSP
-
MDE
2 stops15h 45m
United Airlines
Tue 11/310:40 am
MDE
-
GSP
2 stops26h 59m
United Airlines
Deal found 7/23$614
This United Airlines deal was found by Cheapflights users on 7/23. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 10/147:35 pm
GSP
-
MDE
2 stops26h 35m
United Airlines
Mon 10/199:45 am
MDE
-
GSP
2 stops26h 50m
United Airlines
Deal found 7/23$617
This American Airlines deal was found by Cheapflights users on 7/23. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 11/711:42 am
GSP
-
MDE
1 stop11h 52m
American Airlines
Sun 11/157:30 am
MDE
-
GSP
1 stop11h 42m
American Airlines
Deal found 7/23$630
This United Airlines deal was found by Cheapflights users on 7/23. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 10/296:30 am
GSP
-
MDE
2 stops39h 45m
United Airlines
Tue 11/310:40 am
MDE
-
GSP
1 stop11h 14m
United Airlines
Deal found 7/23$632
This American Airlines deal was found by Cheapflights users on 7/23. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 10/298:00 am
GSP
-
MDE
2 stops13h 15m
American Airlines
Thu 11/53:12 pm
MDE
-
GSP
1 stop8h 40m
American Airlines
Deal found 7/23$635
This American Airlines deal was found by Cheapflights users on 7/23. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 10/238:08 pm
GSP
-
MDE
1 stop25h 07m
American Airlines
Mon 11/237:30 am
MDE
-
GSP
1 stop17h 25m
American Airlines
Deal found 7/23$641
This American Airlines deal was found by Cheapflights users on 7/23. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 10/308:08 pm
GSP
-
MDE
1 stop25h 07m
American Airlines
Thu 11/57:30 am
MDE
-
GSP
1 stop11h 42m
American Airlines
Deal found 7/23$645
This American Airlines deal was found by Cheapflights users on 7/25. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 12/35:15 am
GSP
-
MDE
1 stop18h 24m
American Airlines
Thu 12/107:00 am
MDE
-
GSP
2 stops12h 23m
American Airlines
Deal found 7/25$646
This American Airlines deal was found by Cheapflights users on 7/22. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 12/1512:28 pm
GSP
-
MDE
2 stops11h 11m
American Airlines
Fri 3/121:20 am
MDE
-
GSP
2 stops12h 35m
American Airlines
Deal found 7/22$650

Find flight deals from Greenville to Medellín

Discover tips and strategies to find the most affordable flight options for your journey from Greenville (GSP) to Medellín (CO1). Learn about various techniques such as flexible date searches, comparing prices across and setting up price alerts. Use these methods to find the cheapest flights available for your travel needs. Data last updated July 27, 2026.

Round-trip from

$590
(United Airlines)

One-way from

$203
(Kiwi.com)

Popular in

September

Cheapest in

August

Average price

$777
From Greenville to Medellín
Search Deals
One-way flight from Greenville to Medellín
Search Deals
Highest demand for flights based on searches. 6% potential increase in price ($52 potential increase over avg. RT price).
Search Deals
Cheapest flight prices on average. 1% potential price decrease ($14 potential savings vs. average RT price).
Search Deals
Average for round-trip flights in July 2026
Search Deals

Cheapflights Fare Finder

 
Customize your flight search to find flights from Greenville to Medellín that fit within your specific budget. Explore options based on user searches and filter the results based on your desired price range. Find flights that match your budget for a cost-effective journey. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated July 27, 2026.
Use the filters below to find and compare flights from Greenville to Medellín that are best for you.

Fly from

Fly to

Route

Depart

Return

Price

Cheapest round-trip

GreenvilleMedellín

GSP - MDE

GSPMDE

Greenville

Fri 10/23

6:20 am-9:10 pm

2 stops15h 50m

Medellín Jose Maria Cordova Intl

Mon 11/23

10:40 am-9:51 am

2 stops23h 11m

$590

GreenvilleMedellín

GSP - MDE

GSPMDE

Greenville

Fri 10/30

6:30 am-9:15 pm

2 stops39h 45m

Medellín Jose Maria Cordova Intl

Thu 11/5

10:40 am-9:46 am

2 stops23h 06m

$632

GreenvilleMedellín

GSP - MDE

GSPMDE

Greenville

Sat 11/7

5:40 am-10:05 pm

2 stops16h 25m

Medellín Jose Maria Cordova Intl

Sun 11/15

5:35 am-9:21 pm

2 stops15h 46m

$645

GreenvilleMedellín

GSP - MDE

GSPMDE

Greenville

Fri 10/23

6:06 am-8:15 pm

2 stops15h 09m

Medellín Jose Maria Cordova Intl

Mon 11/23

7:30 am-7:11 pm

1 stop11h 41m

$655

GreenvilleMedellín

GSP - MDE

GSPMDE

Greenville

Sat 1/2

9:02 am-11:39 pm

2 stops14h 37m

Medellín Jose Maria Cordova Intl

Sat 1/23

7:00 am-10:19 pm

2 stops15h 19m

$676

GreenvilleMedellín

GSP - MDE

GSPMDE

Greenville

Mon 8/17

10:33 am-9:10 pm

2 stops35h 37m

Medellín Jose Maria Cordova Intl

Mon 9/14

9:45 am-9:35 am

2 stops22h 50m

$677

GreenvilleMedellín

GSP - MDE

GSPMDE

Greenville

Sun 9/6

1:28 pm-11:05 pm

2 stops10h 37m

Medellín Jose Maria Cordova Intl

Sun 9/13

7:50 am-12:50 pm

2 stops28h 00m

$680
Quickest round-trip

GreenvilleMedellín

GSP - MDE

GSPMDE

Greenville

Tue 12/15

12:28 pm-11:39 pm

2 stops11h 11m

Medellín Jose Maria Cordova Intl

Fri 3/12

1:20 am-1:55 pm

2 stops12h 35m

$690

GreenvilleMedellín

GSP - MDE

GSPMDE

Greenville

Fri 8/14

6:30 am-9:10 pm

2 stops15h 40m

Medellín Jose Maria Cordova Intl

Mon 9/14

9:45 am-9:35 am

2 stops22h 50m

$701

GreenvilleMedellín

GSP - MDE

GSPMDE

Greenville

Wed 8/12

5:43 pm-9:10 pm

2 stops28h 27m

Medellín Jose Maria Cordova Intl

Tue 8/18

9:45 am-1:32 pm

2 stops26h 47m

$720

Flights are sorted by cheapest round-trip flights first.

Deals found on 7/26

Showing 1-10 of 23 resultsSorted by cheapest first
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Best time to book a flight from Greenville to Medellín

Have a flexible travel schedule? Discover the best time to fly to Medellín from Greenville with our price prediction graph.
Estimated round-trip price
Rates are based on past data. Find the cheapest month and day to book your flight based on your travel requirements, then search for cheap deals.

Cheapflights Insights

Everything you need to know about your flight from Greenville to Medellín

What is the cheapest month to book a flight from Greenville to Medellín?

Currently, August is the cheapest month in which you can book a flight from Greenville to Medellín (average of $655). Flying from Greenville to Medellín in September is currently the most expensive (average of $931). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.

How much does it cost to fly round-trip from Greenville to Medellín?

Airfare is below average for this route at the moment.
Greenville to Medellín flights typically cost between $619 and $676 in October.
The cheapest round-trip price found within the last 5 days was $590 on United Airlines (Oct 23-Nov 23).

How far ahead should I book a flight from Greenville to Medellín?

The best time to book flights from Greenville to Medellín is 43 days before your desired departure date. The cost of your flight will likely increase significantly if you book two weeks in advance of your flight.

Reviews of airlines servicing Medellín

Get insights into the airlines that provide service to Medellín. Read reviews, discover amenities, and learn about the overall travel experience offered by airlines. Use this information to make informed decisions when choosing an airline for your flight to Medellín. Reviews last updated July 27, 2026.
Get a feel of what it's like to fly with American Airlines from Greenville to Medellín by reading reviews from past customers. Users have also rated airlines in terms of entertainment options, comfort, food, crew/service, and boarding process.
American Airlines
7.1
Good
11,837 reviews

Food

6.4

Overall

7.1

Boarding

7.5

Comfort

7.2

Entertainment

6.8

Crew

7.9

Reviews

1 / 20
10.0
Excellent

Linda,Jul 2026

ROA - CLT

Very helpful and friendly people who pushed me where I needed to go
American Airlines
7.1
Good
11,837 reviews
American Airlines
7.1
Good
11,837 reviews

Food

6.4

Overall

7.1

Boarding

7.5

Comfort

7.2

Entertainment

6.8

Crew

7.9

Reviews

1 / 20
10.0
Excellent

Linda,Jul 2026

ROA - CLT

Very helpful and friendly people who pushed me where I needed to go

Related info for your journey

Find useful and relevant information for your journey from Greenville to Medellín. Access travel guides, tips, and recommendations to enhance your travel experience. Get information about local attractions, weather, transportation options, and more.

  • What airport do you fly from for flights from Greenville to Medellín?

    If you book a flight to Medellín from Greenville, you will be flying from Greenville, which is the city’s only airport. Greenville (GSP) is located 10.4 mi from the center of Greenville. There are 0 flights from Greenville to Medellín per day from 1 airline.

  • How long is the flight from Greenville to Medellín?

    United Airlines, Delta, and American Airlines can get you from Greenville to Medellín in just under 15h 09m. Your travel time can differ by up to 1h 16m. Airlines will cover a distance of 2030 mi. This flight may include one or multiple stops.

  • What is the cheapest airline to fly from Greenville to Medellín round-trip?

    American Airlines, at $515, was found to be the cheapest airline from Greenville to Medellín.. Users have found that American Airlines is 33% cheaper than the other options available to this destination.

  • Can I find deals for flights from Greenville to Medellín that include hotel bookings?

    Yes. In addition to deals on Greenville to Medellín flights, Cheapflights offers vacation packages that include both flights and hotel.

  • How can I find direct flights from Greenville to Medellín?

    After entering your origin and destination, apply the non-stop filter on the search result page to find direct flights from Greenville to Medellín.

  • Can I find deals for business class flights from Greenville to Medellín?

    Yes. Cheapflights offers flight deals from Greenville to Medellín by cabin class. In addition to browsing deals, you can also filter by cabin class on the search results page after making a search.

  • What is the cheapest month to book a flight from Greenville to Medellín?

    Currently, August is the cheapest month in which you can book a flight from Greenville to Medellín (average of $655). Flying from Greenville to Medellín in September is currently the most expensive (average of $931). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.

See more FAQs

Browse thousands of different options on Cheapflights for your next trip

Toggle through the tabs below to find thousands of options on Cheapflights for your next trip.

Top airline flying from Greenville to Medellín

Discover the top airline that operate flights from Greenville to Medellín. Compare their services, reliability, and customer satisfaction ratings to choose the airline that best suits your travel preferences and needs. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated July 27, 2026.
AirlineCheapestAverageFlexibilityOn-time
American AirlinesCheapest$515Average$761FlexibilityNo cancel feeOn-time71%

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