$293+ Cheap flights from Greenville (GSP) to Medellín
This is the cheapest round-trip flight price found by a Cheapflights user in the last 72 hours by searching for a flight departing on 12/13. Fares are subject to change and may not be available on all flights or dates of travel.
GSP — MDE
Dec 5 — Dec 121
Round-trip
1 adult, Economy
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Find cheap flights from Greenville to Medellín with Cheapflights
1. Tell us where you want to go
Enter your travel information like dates, passengers, trip type (one-way or round trip), and preferred cabin class then click “Find deals”2. Select your favorite providers
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Review each provider’s pricing and select the best option for you! Book through your favorite provider’s website for a seamless experience.Cheap flight deals from Greenville to Medellín
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Best
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Cheapest flights from Greenville to MedellínExplore the most affordable flight options available from Greenville to Medellín. Find the lowest fares from popular airlines and budget airlines, with prices last updated on November 5, 2026.
Explore the most affordable flight options available from Greenville to Medellín. Find the lowest fares from popular airlines and budget airlines, with prices last updated on November 5, 2026.
This Kiwi.com deal was found by Cheapflights users on 11/1. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 12/243:28 pm -
1 stop20h 32m
Sun 12/271:10 pm -
1 stop26h 37m
Deal found 11/1![Multiple Airlines logo]()
$674
This Trip.com deal was found by Cheapflights users on 10/30. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Trip.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 11/139:41 am -
2 stops22h 34m
Sat 11/219:15 am -
2 stops22h 39m
Deal found 10/30![Multiple Airlines logo]()
$682
This United Airlines deal was found by Cheapflights users on 11/3. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 11/165:37 pm -
2 stops28h 33m
Sat 12/1910:40 am -
2 stops22h 48m
Deal found 11/3![United Airlines logo]()
$719
This United Airlines deal was found by Cheapflights users on 11/3. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 11/225:12 pm -
1 stop28h 58m
Fri 12/1810:40 am -
1 stop11h 09m
Deal found 11/3![United Airlines logo]()
$727
This United Airlines deal was found by Cheapflights users on 11/3. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 11/176:20 am -
2 stops15h 50m
Fri 12/181:10 am -
1 stop20h 39m
Deal found 11/3![United Airlines logo]()
$730
This United Airlines deal was found by Cheapflights users on 11/3. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 11/225:12 pm -
1 stop28h 58m
Sat 12/1210:40 am -
2 stops22h 51m
Deal found 11/3![United Airlines logo]()
$731
This American Airlines deal was found by Cheapflights users on 10/31. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 11/218:16 pm -
1 stop25h 01m
Fri 12/41:30 am -
2 stops14h 40m
Deal found 10/31![American Airlines logo]()
$732
This United Airlines deal was found by Cheapflights users on 11/3. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 12/15:34 pm -
2 stops28h 36m
Tue 12/810:40 am -
1 stop11h 19m
Deal found 11/3![United Airlines logo]()
$743
This American Airlines deal was found by Cheapflights users on 10/31. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 11/236:00 am -
2 stops15h 17m
Fri 12/111:30 am -
2 stops14h 06m
Deal found 10/31![American Airlines logo]()
$751
This United Airlines deal was found by Cheapflights users on 10/31. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 11/175:12 pm -
1 stop28h 58m
Fri 12/410:40 am -
1 stop11h 19m
Deal found 10/31![United Airlines logo]()
$752
Best flights from Greenville to MedellínDiscover carefully curated flight deals from Greenville to Medellín that have cost, travel time, and layovers in mind to ensure you get the best travel experience. Data last updated November 5, 2026.
Discover carefully curated flight deals from Greenville to Medellín that have cost, travel time, and layovers in mind to ensure you get the best travel experience. Data last updated November 5, 2026.
This United Airlines deal was found by Cheapflights users on 10/31. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 11/235:37 pm -
2 stops28h 33m
Fri 12/1810:40 am -
1 stop11h 09m
Deal found 10/31![United Airlines logo]()
$719
This Copa Airlines deal was found by Cheapflights users on 11/3. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Copa Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 2/47:42 pm -
2 stops12h 33m
Tue 2/95:00 am -
2 stops14h 07m
Deal found 11/3![Copa Airlines logo]()
$787
This American Airlines deal was found by Cheapflights users on 11/1. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 11/218:16 pm -
1 stop25h 01m
Mon 11/307:30 am -
1 stop17h 25m
Deal found 11/1![American Airlines logo]()
$810
This LATAM Airlines deal was found by Cheapflights users on 10/31. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure LATAM Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 4/267:45 am -
2 stops25h 05m
Fri 4/306:25 am -
2 stops26h 00m
Deal found 10/31![LATAM Airlines logo]()
$849
This United Airlines deal was found by Cheapflights users on 11/3. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 11/225:37 pm -
2 stops28h 33m
Fri 12/1110:40 am -
1 stop11h 19m
Deal found 11/3![United Airlines logo]()
$719
This United Airlines deal was found by Cheapflights users on 10/31. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 11/235:37 pm -
2 stops28h 33m
Mon 12/710:40 am -
2 stops23h 12m
Deal found 10/31![United Airlines logo]()
$719
This Copa Airlines deal was found by Cheapflights users on 10/31. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Copa Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 11/1910:26 am -
2 stops12h 24m
Sat 12/54:30 pm -
2 stops26h 43m
Deal found 10/31![Copa Airlines logo]()
$793
This American Airlines deal was found by Cheapflights users on 10/30. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 11/298:16 pm -
1 stop17h 55m
Fri 12/111:30 am -
2 stops14h 06m
Deal found 10/30![American Airlines logo]()
$847
This United Airlines deal was found by Cheapflights users on 10/31. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 11/176:20 am -
2 stops15h 50m
Thu 12/310:40 am -
2 stops47h 12m
Deal found 10/31![United Airlines logo]()
$737
This United Airlines deal was found by Cheapflights users on 11/3. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 2/46:30 am -
1 stop15h 40m
Tue 2/910:40 am -
2 stops23h 21m
Deal found 11/3![United Airlines logo]()
$795
This United Airlines deal was found by Cheapflights users on 11/2. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 4/266:30 am -
2 stops39h 40m
Fri 4/309:45 am -
2 stops23h 11m
Deal found 11/2![United Airlines logo]()
$861
Last-minute flights from Greenville to MedellínDiscover last-minute flight deals from Greenville to Medellín. Data last updated November 5, 2026 and is based on user searches.
Discover last-minute flight deals from Greenville to Medellín. Data last updated November 5, 2026 and is based on user searches.
This Trip.com deal was found by Cheapflights users on 10/30. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Trip.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 11/139:41 am -
2 stops22h 34m
Sat 11/219:15 am -
2 stops22h 39m
Deal found 10/30![Multiple Airlines logo]()
$682
This United Airlines deal was found by Cheapflights users on 11/3. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 11/165:37 pm -
2 stops28h 33m
Sat 12/1910:40 am -
2 stops22h 48m
Deal found 11/3![United Airlines logo]()
$719
This United Airlines deal was found by Cheapflights users on 11/3. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 11/176:20 am -
2 stops15h 50m
Fri 12/181:10 am -
1 stop20h 39m
Deal found 11/3![United Airlines logo]()
$730
This United Airlines deal was found by Cheapflights users on 10/31. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 11/175:12 pm -
1 stop28h 58m
Fri 12/410:40 am -
1 stop11h 19m
Deal found 10/31![United Airlines logo]()
$752
This American Airlines deal was found by Cheapflights users on 10/31. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 11/218:16 pm -
1 stop25h 01m
Fri 12/41:30 am -
2 stops14h 40m
Deal found 10/31![American Airlines logo]()
$732
This United Airlines deal was found by Cheapflights users on 11/3. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 11/225:12 pm -
1 stop28h 58m
Fri 12/1810:40 am -
1 stop11h 09m
Deal found 11/3![United Airlines logo]()
$727
This United Airlines deal was found by Cheapflights users on 11/3. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 11/225:12 pm -
1 stop28h 58m
Sat 12/1210:40 am -
2 stops22h 51m
Deal found 11/3![United Airlines logo]()
$731
This American Airlines deal was found by Cheapflights users on 10/31. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 11/236:00 am -
2 stops15h 17m
Fri 12/111:30 am -
2 stops14h 06m
Deal found 10/31![American Airlines logo]()
$751
This United Airlines deal was found by Cheapflights users on 11/3. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 12/15:34 pm -
2 stops28h 36m
Tue 12/810:40 am -
1 stop11h 19m
Deal found 11/3![United Airlines logo]()
$743
This Kiwi.com deal was found by Cheapflights users on 11/1. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 12/243:28 pm -
1 stop20h 32m
Sun 12/271:10 pm -
1 stop26h 37m
Deal found 11/1![Multiple Airlines logo]()
$674
One-way flights from Greenville to MedellínSearch for one-way flight options from Greenville to Medellín. Find affordable one-way fares based on user searches. Data last updated November 5, 2026.
Search for one-way flight options from Greenville to Medellín. Find affordable one-way fares based on user searches. Data last updated November 5, 2026.
This Kiwi.com deal was found by Cheapflights users on 11/4. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 12/133:49 pm -
1 stop20h 11m
Wed 12/3112:00 am -
Nonstop0h 00m
Deal found 11/4![Multiple Airlines logo]()
$293
This Kiwi.com deal was found by Cheapflights users on 11/2. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 11/1910:12 am -
3 stops21h 53m
Wed 12/3112:00 am -
Nonstop0h 00m
Deal found 11/2![Multiple Airlines logo]()
$322
This Kiwi.com deal was found by Cheapflights users on 11/3. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 11/128:43 am -
1 stop14h 27m
Wed 12/3112:00 am -
Nonstop0h 00m
Deal found 11/3![Multiple Airlines logo]()
$377
This United Airlines deal was found by Cheapflights users on 11/1. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 1/35:16 pm -
1 stop12h 19m
Wed 12/3112:00 am -
Nonstop0h 00m
Deal found 11/1![United Airlines logo]()
$439
This eDestinos deal was found by Cheapflights users on 11/1. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure eDestinos is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 1/36:15 am -
2 stops13h 45m
Wed 12/3112:00 am -
Nonstop0h 00m
Deal found 11/1![LATAM Airlines logo]()
$451
Find flight deals from Greenville to Medellín
Discover tips and strategies to find the most affordable flight options for your journey from Greenville (GSP) to Medellín (CO1). Learn about various techniques such as flexible date searches, comparing prices across and setting up price alerts. Use these methods to find the cheapest flights available for your travel needs. Data last updated November 5, 2026.
Round-trip from | $639 (American Airlines) |
|---|---|
One-way from | $293 (Kiwi.com) |
Popular in | November |
Cheapest in | September |
Average price | $1,122 |
Cheapflights Fare Finder
Customize your flight search to find flights from Greenville to Medellín that fit within your specific budget. Explore options based on user searches and filter the results based on your desired price range. Find flights that match your budget for a cost-effective journey. Over the last 7 days, Cheapflights users made 7,457,451 searches. Data last updated November 5, 2026.
Use the filters below to find and compare flights from Greenville to Medellín that are best for you.
Fly from
Fly to
Route
Depart
Return
Cheapest round-trip
GreenvilleMedellín
GSP Greenville - MDE Medellín Jose Maria Cordova Intl
GSPMDE
Greenville
Sun 12/13
3:49 pm-12:00 pm
1 stop20h 11m
Medellín Jose Maria Cordova Intl
Wed 12/31
12:00 am-12:00 am
Nonstop0h 00m
$293
GreenvilleMedellín
GSP Greenville - MDE Medellín Jose Maria Cordova Intl
GSPMDE
Greenville
Thu 11/12
8:43 am-11:10 pm
1 stop14h 27m
Medellín Jose Maria Cordova Intl
Wed 12/31
12:00 am-12:00 am
Nonstop0h 00m
$377
GreenvilleMedellín
GSP Greenville - MDE Medellín Jose Maria Cordova Intl
GSPMDE
Greenville
Sun 1/3
7:37 pm-10:10 pm
2 stops26h 33m
Medellín Jose Maria Cordova Intl
Wed 12/31
12:00 am-12:00 am
Nonstop0h 00m
$429
Quickest round-trip
GreenvilleMedellín
GSP Greenville - MDE Medellín Jose Maria Cordova Intl
GSPMDE
Greenville
Sun 1/3
6:15 am-8:00 pm
2 stops13h 45m
Medellín Jose Maria Cordova Intl
Wed 12/31
12:00 am-12:00 am
Nonstop0h 00m
$455
GreenvilleMedellín
GSP Greenville - MDE Medellín Jose Maria Cordova Intl
GSPMDE
Greenville
Sun 1/3
5:30 am-9:13 pm
1 stop15h 43m
Medellín Jose Maria Cordova Intl
Wed 12/31
12:00 am-12:00 am
Nonstop0h 00m
$528
GreenvilleMedellín
GSP Greenville - MDE Medellín Jose Maria Cordova Intl
GSPMDE
Greenville
Sun 12/13
7:48 pm-8:00 pm
2 stops24h 12m
Medellín Jose Maria Cordova Intl
Wed 12/31
12:00 am-12:00 am
Nonstop0h 00m
$534
GreenvilleMedellín
GSP Greenville - MDE Medellín Jose Maria Cordova Intl
GSPMDE
Greenville
Mon 11/23
5:37 pm-10:10 pm
2 stops28h 33m
Medellín Jose Maria Cordova Intl
Fri 12/18
10:40 am-9:49 pm
1 stop11h 09m
$719
GreenvilleMedellín
GSP Greenville - MDE Medellín Jose Maria Cordova Intl
GSPMDE
Greenville
Sun 11/22
5:37 pm-10:10 pm
2 stops28h 33m
Medellín Jose Maria Cordova Intl
Fri 12/11
10:40 am-9:59 pm
1 stop11h 19m
$719
GreenvilleMedellín
GSP Greenville - MDE Medellín Jose Maria Cordova Intl
GSPMDE
Greenville
Mon 11/23
5:37 pm-10:10 pm
2 stops28h 33m
Medellín Jose Maria Cordova Intl
Mon 12/7
10:40 am-9:52 am
2 stops23h 12m
$719
GreenvilleMedellín
GSP Greenville - MDE Medellín Jose Maria Cordova Intl
GSPMDE
Greenville
Tue 11/17
6:20 am-10:10 pm
2 stops15h 50m
Medellín Jose Maria Cordova Intl
Thu 12/3
10:40 am-9:52 am
2 stops47h 12m
$737
Showing 1-10 of 17 resultsSorted by cheapest first
Best time to book a flight from Greenville to Medellín
Have a flexible travel schedule? Discover the best time to fly to Medellín from Greenville with our price prediction graph.
GSP-CO1
GSP-MDE
Estimated round-trip price
Rates are based on past data. Find the cheapest month and day to book your flight based on your travel requirements, then search for cheap deals.
Cheapflights Insights
Everything you need to know about your flight from Greenville to Medellín
GSP-CO1
GSP-MDE
What is the cheapest month to book a flight from Greenville to Medellín?
Currently, September is the cheapest month in which you can book a flight from Greenville to Medellín (average of $574). Flying from Greenville to Medellín in November is currently the most expensive (average of $1,122). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.
Reviews of airlines servicing Medellín
Get insights into the airlines that provide service to Medellín. Read reviews, discover amenities, and learn about the overall travel experience offered by airlines. Use this information to make informed decisions when choosing an airline for your flight to Medellín. Reviews last updated November 5, 2026.
Get a feel of what it's like to fly with American Airlines from Greenville to Medellín by reading reviews from past customers. Users have also rated airlines in terms of entertainment options, comfort, food, crew/service, and boarding process.
Entertainment
6.8
Food
6.4
Comfort
7.2
Crew
7.9
Boarding
7.4
Overall
7.0
Reviews
1 / 20
10.0
ExcellentLinda,Jul 2026
ROA - CLT
Entertainment
6.8
Food
6.4
Comfort
7.2
Crew
7.9
Boarding
7.4
Overall
7.0
Reviews
1 / 20
10.0
ExcellentLinda,Jul 2026
ROA - CLT
Related info for your journey
Find useful and relevant information for your journey from Greenville to Medellín. Access travel guides, tips, and recommendations to enhance your travel experience. Get information about local attractions, weather, transportation options, and more.
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Complete your trip
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Find flights from Greenville to Medellín, based on your preferred cabin class, be it economy, premium economy, business, or first class.
Greenville and Medellín flights
Browse other Greenville and Medellín flight options. Last updated on November 5, 2026.
Other flights from Greenville
Browse through other flights departing from Greenville. Flights are based on user searches made on Cheapflights and were last updated on November 5, 2026.
Popular flight searches
Check out other popular destinations found by fellow travelers in 2026
Top airline flying from Greenville to Medellín
Discover the top airline that operate flights from Greenville to Medellín. Compare their services, reliability, and customer satisfaction ratings to choose the airline that best suits your travel preferences and needs. Over the last 7 days, Cheapflights users made 7,457,451 searches. Data last updated November 5, 2026.
| Airline | Cheapest | Average | Flexibility | On-time |
|---|---|---|---|---|
| Cheapest$615 | Average$817 | FlexibilityNo cancel fee | On-time71% |