HomeSearch by dateVacation packagesHotelsFlight dealsCar rentalTravel tips & news
Medellín

$274+ Cheap flights from Greenville (GSP) to Medellín

This is the cheapest one-way flight price found by a Cheapflights user in the last 72 hours by searching for a flight departing on 10/1. Fares are subject to change and may not be available on all flights or dates of travel.
GSP — MDE
May 4 — May 111
Sun 5/4
Sun 5/11
1 adult, Economy
We work with more than 300 partners to bring you better travel deals

Find cheap flights from Greenville to Medellín with Cheapflights

1. Tell us where you want to go

Enter your travel information like dates, passengers, trip type (one-way or round trip), and preferred cabin class then click “Find deals”

2. Select your favorite providers

We find the providers serving your travel needs. Choose up to four travel providers to compare side-by-side for flights, hotels, or car rentals.

3. Compare prices and book

Review each provider’s pricing and select the best option for you! Book through your favorite provider’s website for a seamless experience.

Cheapflights Tip: The best prices from Greenville to Medellín are usually found in March or January, booked 57 days in advance, depart on a Wednesday or Monday and return on a Tuesday

Cheap flight deals from Greenville to Medellín

Discover tips and strategies to find the most affordable flight options for your journey from Greenville (GSP) to Medellín (CO1). Learn about various techniques such as flexible date searches, comparing prices across and setting up price alerts. Use these methods to find the cheapest flights available for your travel needs. Data last updated April 29, 2025.

Round-trip from

$510
(American Airlines)

One-way from

$274
(Copa Airlines)

Popular in

December

Cheapest in

March

Average price

$641
From Greenville to Medellín
Search Deals
One-way flight from Greenville to Medellín
Search Deals
Highest demand for flights based on searches. 4% potential increase in price ($34 potential increase over avg. RT price).
Search Deals
Cheapest flight prices on average. 2% potential price decrease ($19 potential savings vs. average RT price).
Search Deals
Average for round-trip flights in April 2025
Search Deals

Find flight deals from Greenville to Medellín

Cheapest flights from Greenville to Medellín
Explore the most affordable flight options available from Greenville to Medellín. Find the lowest fares from popular airlines and budget airlines, with prices last updated on April 29, 2025.

This American Airlines deal was found by Cheapflights users on 4/28. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 10/205:31 amGSP - MDE
2 stops15h 24mAmerican Airlines
Tue 10/285:50 amMDE - GSP
2 stops14h 32mAmerican Airlines
Deal found 4/28$510
This Mytrip deal was found by Cheapflights users on 4/27. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Mytrip is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 5/23:55 pmGSP - MDE
1 stop22h 20mMultiple Airlines
Sat 5/242:13 pmMDE - GSP
2 stops30h 07mMultiple Airlines
Deal found 4/27$525
This United Airlines deal was found by Cheapflights users on 4/28. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 6/135:18 pmGSP - MDE
1 stop12h 24mUnited Airlines
Sat 6/289:45 amMDE - GSP
1 stop30h 05mUnited Airlines
Deal found 4/28$555
This LATAM Airlines deal was found by Cheapflights users on 4/28. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure LATAM Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 5/37:25 amGSP - MDE
2 stops9h 57mLATAM Airlines
Mon 5/268:47 amMDE - GSP
2 stops14h 05mLATAM Airlines
Deal found 4/28$882

Cheapflights Fare Finder

Customize your flight search to find flights from Greenville to Medellín that fit within your specific budget. Explore options based on user searches and filter the results based on your desired price range. Find flights that match your budget for a cost-effective journey. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated April 29, 2025.
Use the filters below to find and compare flights from Greenville to Medellín that are best for you.

Fly from

Greenville

Fly to

Medellín

Route

Depart

Return

Price

GreenvilleMedellín

GSP - MDE

GSPMDE

Greenville

Mon 10/20

5:31 am-7:55 pm

2 stops15h 24m

Medellín Jose Maria Cordova Intl

Tue 10/28

5:50 am-7:26 pm

1 stop12h 36m

$510

GreenvilleMedellín

GSP - MDE

GSPMDE

Greenville

Fri 6/13

5:18 pm-4:42 am

1 stop12h 24m

Medellín Jose Maria Cordova Intl

Sat 6/28

9:45 am-4:50 pm

1 stop30h 05m

$555

GreenvilleMedellín

GSP - MDE

GSPMDE

Greenville

Mon 10/20

7:45 am-7:55 pm

2 stops13h 10m

Medellín Jose Maria Cordova Intl

Tue 10/28

6:03 pm-6:49 pm

3 stops23h 46m

$1,332

GreenvilleMedellín

GSP - MDE

GSPMDE

Greenville

Wed 10/1

10:10 am-9:37 am

2 stops24h 27m

$274

GreenvilleMedellín

GSP - MDE

GSPMDE

Greenville

Wed 10/1

5:57 am-12:42 pm

1 stop7h 45m

$310

GreenvilleMedellín

GSP - MDE

GSPMDE

Greenville

Sat 5/31

5:30 am-5:58 pm

2 stops13h 28m

$672

GreenvilleMedellín

GSP - MDE

GSPMDE

Greenville

Sat 5/10

11:21 am-12:22 pm

3 stops26h 01m

$863

Flights are sorted by cheapest round-trip flights first.

Deals found on 4/28

Best time to book a flight from Greenville to Medellín

Have a flexible travel schedule? Discover the best time to fly to Medellín from Greenville with our price prediction graph.
Estimated round-trip price
Rates are based on past data. Find the cheapest month and day to book your flight based on your travel requirements, then search for cheap deals.

Cheapflights Insights

Everything you need to know about your flight from Greenville to Medellín

How far ahead should I book a flight from Greenville to Medellín?

Use this chart to determine the optimal time to book a round-trip flight from Greenville to Medellín. Price data was last updated on April 25, 2025.

The best time to book flights from Greenville to Medellín is 57 days before your desired departure date. The cost of your flight will likely increase significantly if you book two weeks in advance of your flight.

What is the cheapest month to book a flight from Greenville to Medellín?

Currently, January is the cheapest month in which you can book a flight from Greenville to Medellín (average of $378). Flying from Greenville to Medellín in December is currently the most expensive (average of $625). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.

What is the cheapest time of day to fly from GSP to MDE?

Find hourly flight availability from Greenville to Medellín. Discover flight options and departure times throughout the day, allowing you to choose a departure time that suits your schedule. Data last updated April 29, 2025.

One of the essential ways to save on airfare from Greenville to Medellín is to remain as flexible as possible. Flights that are in the morning tend to be the most expensive. A flight in the evening could potentially save you up to 24% on airfare.

Rainfall in Medellín by month

Plan your trip to Medellín by taking into account the average rainfall totals by month.

In terms of precipitation, rainfall in Medellín ranges from 2.0 - 7.9 inches per month. October is typically the wettest month, when rainfall can reach 7.9 in. January is typically the driest time to visit Medellín when rainfall is around 2.0 in.

Temperature in Medellín by month

Plan your trip to Medellín by taking into account the average temperature totals by month.

If weather is an important factor for your trip to Medellín, use this chart to help with planning. For those seeking warmer temperatures, January is the ideal time of year to visit, when temperatures reach an average of 71.6 F. Travelers looking to avoid the cold should look outside of October, when temperatures are typically at their lowest (around 69.8 F).

Reviews of airlines servicing Medellín

Get insights into the airlines that provide service to Medellín. Read reviews, discover amenities, and learn about the overall travel experience offered by airlines. Use this information to make informed decisions when choosing an airline for your flight to Medellín. Reviews last updated April 29, 2025.
Delta
8.0
Very good
7,936 reviews

Comfort

7.9

Food

7.3

Entertainment

7.9

Crew

8.5

Boarding

8.2

Overall

8.0

Reviews

1 / 20
10.0
Excellent

Aaron,Oct 2024

LAX - LHR

This was a flight operated by Virgin Atlantic in their Upper Class cabin. Overall, an outstanding experience.
Delta
8.0
Very good
7,936 reviews
Delta
8.0
Very good
7,936 reviews

Comfort

7.9

Food

7.3

Entertainment

7.9

Crew

8.5

Boarding

8.2

Overall

8.0

Reviews

1 / 20
10.0
Excellent

Aaron,Oct 2024

LAX - LHR

This was a flight operated by Virgin Atlantic in their Upper Class cabin. Overall, an outstanding experience.
LATAM Airlines
7.5
Good
1,767 reviews
Delta
8.0
Very good
7,936 reviews

Comfort

7.9

Food

7.3

Entertainment

7.9

Crew

8.5

Boarding

8.2

Overall

8.0

Reviews

1 / 20
10.0
Excellent

Aaron,Oct 2024

LAX - LHR

This was a flight operated by Virgin Atlantic in their Upper Class cabin. Overall, an outstanding experience.
Copa Airlines
7.5
Good
1,411 reviews
Delta
8.0
Very good
7,936 reviews

Comfort

7.9

Food

7.3

Entertainment

7.9

Crew

8.5

Boarding

8.2

Overall

8.0

Reviews

1 / 20
10.0
Excellent

Aaron,Oct 2024

LAX - LHR

This was a flight operated by Virgin Atlantic in their Upper Class cabin. Overall, an outstanding experience.
United Airlines
7.4
Good
8,696 reviews
Delta
8.0
Very good
7,936 reviews

Comfort

7.9

Food

7.3

Entertainment

7.9

Crew

8.5

Boarding

8.2

Overall

8.0

Reviews

1 / 20
10.0
Excellent

Aaron,Oct 2024

LAX - LHR

This was a flight operated by Virgin Atlantic in their Upper Class cabin. Overall, an outstanding experience.
American Airlines
7.2
Good
10,000 reviews
Delta
8.0
Very good
7,936 reviews

Comfort

7.9

Food

7.3

Entertainment

7.9

Crew

8.5

Boarding

8.2

Overall

8.0

Reviews

1 / 20
10.0
Excellent

Aaron,Oct 2024

LAX - LHR

This was a flight operated by Virgin Atlantic in their Upper Class cabin. Overall, an outstanding experience.

Related info for your journey

Find useful and relevant information for your journey from Greenville to Medellín. Access travel guides, tips, and recommendations to enhance your travel experience. Get information about local attractions, weather, transportation options, and more.

  • What airport do you fly from for flights from Greenville to Medellín?

    If you book a flight to Medellín from Greenville, you will be flying from Greenville, which is the city’s only airport. Greenville (GSP) is located 10.4 mi from the center of Greenville. There are 0 flights from Greenville to Medellín per day from 2 different airlines.

  • What are the cheapest airlines flying from Greenville to Medellín round-trip?

    American Airlines, at $510, was found to be the cheapest airline from Greenville to Medellín.Alternate airlines to your destination round-trip include United Airlines and LATAM Airlines. Users have found that American Airlines is 24% cheaper than the other options available to this destination.

  • What are the cheapest airlines to fly from Greenville to Medellín one-way?

    $274 is the cheapest one-way deal found within the past few days, from Copa Airlines. You may also be able to find cheap deals on American Airlines and Delta, with prices starting from $310 and $672, respectively.

  • Can I find deals for flights from Greenville to Medellín that include hotel bookings?

    Yes. In addition to deals on Greenville to Medellín flights, Cheapflights offers vacation packages that include both flights and hotel.

  • How can I find direct flights from Greenville to Medellín?

    After entering your origin and destination, apply the non-stop filter on the search result page to find direct flights from Greenville to Medellín.

  • Can I find deals for business class flights from Greenville to Medellín?

    Yes. Cheapflights offers flight deals from Greenville to Medellín by cabin class. In addition to browsing deals, you can also filter by cabin class on the search results page after making a search.

  • What is the cheapest month to book a flight from Greenville to Medellín?

    Currently, January is the cheapest month in which you can book a flight from Greenville to Medellín (average of $378). Flying from Greenville to Medellín in December is currently the most expensive (average of $625). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.

See more FAQs

Browse thousands of different options on Cheapflights for your next trip

Toggle through the tabs below to find thousands of options on Cheapflights for your next trip.

Alternative routes for Greenville to Medellín

See prices for flight routes from nearby airports that may be better suited for you.
Charlotte to Jose Maria Cordova Intl flights
Charlotte to Bogotá flights
Charlotte to Cartagena flights
Greenville to Jose Maria Cordova Intl flights
Greenville to Bogotá flights
Charlotte to Barranquilla flights
Charlotte to Cali flights
Charleston to Jose Maria Cordova Intl flights
Charleston to Cartagena flights
Charlotte to San Andrés flights
Charleston to Bogotá flights
Savannah to Jose Maria Cordova Intl flights
Myrtle Beach to Jose Maria Cordova Intl flights
Myrtle Beach to Cali flights
Savannah to Bogotá flights
Charlotte to Pereira flights
Myrtle Beach to Cartagena flights
Columbia to Barranquilla flights
Columbia to Cartagena flights
Charlotte to Armenia flights
Charlotte to Cúcuta flights
Greenville to Cartagena flights
Savannah to Cartagena flights
Greenville to Santa Marta flights
Myrtle Beach to Bogotá flights
Charlotte to Santa Marta flights
Charlotte to Manizales flights
Augusta to Bogotá flights
Charleston to Cúcuta flights
Myrtle Beach to Armenia flights
Greenville to Pereira flights

Top 2 airlines flying from Greenville to Medellín

Discover the top 2 airlines that operate flights from Greenville to Medellín. Compare their services, reliability, and customer satisfaction ratings to choose the airline that best suits your travel preferences and needs. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated April 29, 2025.
AirlineCheapestAverageFlexibilityOn-time
American AirlinesCheapest$467Average$720FlexibilityNo cancel feeOn-time71%
LATAM AirlinesCheapest$565Average$799FlexibilityNo cancel feeOn-time81%

100% Free

Cheapflights is completely free to use, so you can start saving the moment you arrive.

Book with Flexibility

Our users can plan ahead with confidence and find flights with no change fees

Travel Smart

Millions of people come to us for their flight needs every year. We help make travel planning easy by providing useful insights and data-driven graphs that can inform your decisions.