HomeSearch by dateVacation packagesHotelsFlight dealsCar rentalTravel tips & news
Medellín

$133+ Cheap flights from Greenville (GSP) to Medellín

This is the cheapest one-way flight price found by a Cheapflights user in the last 72 hours by searching for a flight departing on 3/23. Fares are subject to change and may not be available on all flights or dates of travel.
GSP — MDE
Feb 26 — Mar 51
Thu 2/26
Thu 3/5
1 adult, Economy
We work with more than 300 partners to bring you better travel deals

Find cheap flights from Greenville to Medellín with Cheapflights

1. Tell us where you want to go

Enter your travel information like dates, passengers, trip type (one-way or round trip), and preferred cabin class then click “Find deals”

2. Select your favorite providers

We find the providers serving your travel needs. Choose up to four travel providers to compare side-by-side for flights, hotels, or car rentals.

3. Compare prices and book

Review each provider’s pricing and select the best option for you! Book through your favorite provider’s website for a seamless experience.

Cheap flight deals from Greenville to Medellín

Cheapest flights from Greenville to Medellín
Explore the most affordable flight options available from Greenville to Medellín. Find the lowest fares from popular airlines and budget airlines, with prices last updated on January 27, 2026.

This American Airlines deal was found by Cheapflights users on 1/26. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 3/214:30 pm
GSP
-
MDE
1 stop7h 09m
American Airlines
Sat 3/287:00 am
MDE
-
GSP
1 stop10h 56m
American Airlines
Deal found 1/26$519
This American Airlines deal was found by Cheapflights users on 1/24. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 8/76:44 pm
GSP
-
MDE
1 stop19h 06m
American Airlines
Fri 8/146:00 am
MDE
-
GSP
1 stop11h 14m
American Airlines
Deal found 1/24$529
This FlightHub deal was found by Cheapflights users on 1/24. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure FlightHub is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 8/76:46 am
GSP
-
MDE
2 stops17h 16m
Avianca
Fri 8/144:28 am
MDE
-
GSP
2 stops15h 43m
Avianca
Deal found 1/24$532
This American Airlines deal was found by Cheapflights users on 1/27. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 4/26:40 am
GSP
-
MDE
1 stop14h 35m
American Airlines
Mon 4/66:00 am
MDE
-
GSP
1 stop17h 21m
American Airlines
Deal found 1/27$543
This United Airlines deal was found by Cheapflights users on 1/27. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 4/210:33 am
GSP
-
MDE
2 stops35h 37m
United Airlines
Mon 4/69:45 am
MDE
-
GSP
2 stops23h 11m
United Airlines
Deal found 1/27$575
This Kiwi.com deal was found by Cheapflights users on 1/27. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 3/136:05 pm
GSP
-
MDE
2 stops27h 26m
Multiple Airlines
Thu 3/191:17 am
MDE
-
GSP
1 stop12h 24m
Multiple Airlines
Deal found 1/27$577
This United Airlines deal was found by Cheapflights users on 1/24. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 6/67:45 pm
GSP
-
MDE
2 stops26h 25m
United Airlines
Fri 6/129:45 am
MDE
-
GSP
2 stops30h 10m
United Airlines
Deal found 1/24$585
This American Airlines deal was found by Cheapflights users on 1/24. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 9/46:44 pm
GSP
-
MDE
1 stop19h 06m
American Airlines
Sat 9/123:05 pm
MDE
-
GSP
1 stop19h 50m
American Airlines
Deal found 1/24$601
This United Airlines deal was found by Cheapflights users on 1/24. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 2/224:36 pm
GSP
-
MDE
1 stop29h 29m
United Airlines
Thu 2/2610:45 am
MDE
-
GSP
2 stops33h 56m
United Airlines
Deal found 1/24$606

Find flight deals from Greenville to Medellín

Discover tips and strategies to find the most affordable flight options for your journey from Greenville (GSP) to Medellín (CO1). Learn about various techniques such as flexible date searches, comparing prices across and setting up price alerts. Use these methods to find the cheapest flights available for your travel needs. Data last updated January 27, 2026.

Round-trip from

$519
(American Airlines)

One-way from

$133
(Kiwi.com)

Popular in

September

Cheapest in

March

Average price

$848
From Greenville to Medellín
Search Deals
One-way flight from Greenville to Medellín
Search Deals
Highest demand for flights based on searches. 9% potential increase in price ($78 potential increase over avg. RT price).
Search Deals
Cheapest flight prices on average. 2% potential price decrease ($16 potential savings vs. average RT price).
Search Deals
Average for round-trip flights in January 2026
Search Deals

Cheapflights Fare Finder

 
Customize your flight search to find flights from Greenville to Medellín that fit within your specific budget. Explore options based on user searches and filter the results based on your desired price range. Find flights that match your budget for a cost-effective journey. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated January 27, 2026.
Use the filters below to find and compare flights from Greenville to Medellín that are best for you.

Fly from

Greenville

Fly to

Medellín

Route

Depart

Return

Price

GreenvilleMedellín

GSP - MDE

GSPMDE

Greenville

Sat 3/21

4:30 pm-10:39 pm

1 stop7h 09m

Medellín Jose Maria Cordova Intl

Sat 3/28

7:00 am-6:56 pm

1 stop10h 56m

$519

GreenvilleMedellín

GSP - MDE

GSPMDE

Greenville

Thu 4/2

6:40 am-8:15 pm

1 stop14h 35m

Medellín Jose Maria Cordova Intl

Mon 4/6

6:00 am-12:21 am

1 stop17h 21m

$543

GreenvilleMedellín

GSP - MDE

GSPMDE

Greenville

Thu 4/2

10:33 am-9:10 pm

2 stops35h 37m

Medellín Jose Maria Cordova Intl

Mon 4/6

9:45 am-9:56 am

2 stops23h 11m

$575

GreenvilleMedellín

GSP - MDE

GSPMDE

Greenville

Fri 3/13

6:05 pm-8:31 pm

2 stops27h 26m

Medellín Jose Maria Cordova Intl

Thu 3/19

1:17 am-2:41 pm

1 stop12h 24m

$577

GreenvilleMedellín

GSP - MDE

GSPMDE

Greenville

Sun 2/22

4:36 pm-10:05 pm

1 stop29h 29m

Medellín Jose Maria Cordova Intl

Thu 2/26

10:45 am-8:41 pm

2 stops33h 56m

$606

GreenvilleMedellín

GSP - MDE

GSPMDE

Greenville

Mon 3/23

4:28 pm-12:21 am

1 stop8h 53m

$133

GreenvilleMedellín

GSP - MDE

GSPMDE

Greenville

Sun 3/22

9:46 pm-1:22 pm

1 stop16h 36m

$133

GreenvilleMedellín

GSP - MDE

GSPMDE

Greenville

Fri 3/6

8:18 pm-1:55 pm

1 stop17h 37m

$149

GreenvilleMedellín

GSP - MDE

GSPMDE

Greenville

Fri 3/20

3:31 pm-12:21 am

1 stop9h 50m

$153

GreenvilleMedellín

GSP - MDE

GSPMDE

Greenville

Thu 3/5

4:41 pm-2:13 pm

1 stop21h 32m

$201

Flights are sorted by cheapest round-trip flights first.

Deals found on 1/27

Showing 1-10 of 12 results
1
2

Best time to book a flight from Greenville to Medellín

Have a flexible travel schedule? Discover the best time to fly to Medellín from Greenville with our price prediction graph.
Estimated round-trip price
Rates are based on past data. Find the cheapest month and day to book your flight based on your travel requirements, then search for cheap deals.

Cheapflights Insights

Everything you need to know about your flight from Greenville to Medellín

How far ahead should I book a flight from Greenville to Medellín?

Use this chart to determine the optimal time to book a round-trip flight from Greenville to Medellín. Price data was last updated on January 23, 2026.

The best time to book flights from Greenville to Medellín is 57 days before your desired departure date. The cost of your flight will likely increase significantly if you book two weeks in advance of your flight.

What is the cheapest month to book a flight from Greenville to Medellín?

Currently, February is the cheapest month in which you can book a flight from Greenville to Medellín (average of $270). Flying from Greenville to Medellín in June is currently the most expensive (average of $492). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.

Reviews of airlines servicing Medellín

Get insights into the airlines that provide service to Medellín. Read reviews, discover amenities, and learn about the overall travel experience offered by airlines. Use this information to make informed decisions when choosing an airline for your flight to Medellín. Reviews last updated January 27, 2026.
Get a feel of what it's like to fly with American Airlines from Greenville to Medellín by reading reviews from past customers. Users have also rated airlines in terms of entertainment options, comfort, food, crew/service, and boarding process.
American Airlines
7.2
Good
11,197 reviews

Crew

8.0

Food

6.4

Entertainment

6.9

Overall

7.2

Boarding

7.5

Comfort

7.2

Reviews

1 / 20
2.0
Mediocre

Susie,Jan 2026

CLT - TPA

This flight was delayed 3 or 4 times. We had boarded the plane, sat on plane for a good 30 minutes, then we had to board the aircraft, walk to a different gate, wait and then board another aircraft. We arrived in Tampa 4 hours later than the original booking. I feel there should have been some sort of compensation especially for the advantage members.
American Airlines
7.2
Good
11,197 reviews
American Airlines
7.2
Good
11,197 reviews

Crew

8.0

Food

6.4

Entertainment

6.9

Overall

7.2

Boarding

7.5

Comfort

7.2

Reviews

1 / 20
2.0
Mediocre

Susie,Jan 2026

CLT - TPA

This flight was delayed 3 or 4 times. We had boarded the plane, sat on plane for a good 30 minutes, then we had to board the aircraft, walk to a different gate, wait and then board another aircraft. We arrived in Tampa 4 hours later than the original booking. I feel there should have been some sort of compensation especially for the advantage members.

Related info for your journey

Find useful and relevant information for your journey from Greenville to Medellín. Access travel guides, tips, and recommendations to enhance your travel experience. Get information about local attractions, weather, transportation options, and more.

  • What airport do you fly from for flights from Greenville to Medellín?

    If you book a flight to Medellín from Greenville, you will be flying from Greenville, which is the city’s only airport. Greenville (GSP) is located 10.4 mi from the center of Greenville. There are 0 flights from Greenville to Medellín per day from 2 different airlines.

  • How long is the flight from Greenville to Medellín?

    American Airlines and United Airlines can get you from Greenville to Medellín in just under 7h 09m. Your travel time can differ by up to 28h 28m. Airlines will cover a distance of 2030 mi. This flight may include one or multiple stops.

  • What is the cheapest airline to fly from Greenville to Medellín round-trip?

    American Airlines, at $515, was found to be the cheapest airline from Greenville to Medellín.. Users have found that American Airlines is 31% cheaper than the other options available to this destination.

  • Can I find deals for flights from Greenville to Medellín that include hotel bookings?

    Yes. In addition to deals on Greenville to Medellín flights, Cheapflights offers vacation packages that include both flights and hotel.

  • How can I find direct flights from Greenville to Medellín?

    After entering your origin and destination, apply the non-stop filter on the search result page to find direct flights from Greenville to Medellín.

  • Can I find deals for business class flights from Greenville to Medellín?

    Yes. Cheapflights offers flight deals from Greenville to Medellín by cabin class. In addition to browsing deals, you can also filter by cabin class on the search results page after making a search.

  • What is the cheapest month to book a flight from Greenville to Medellín?

    Currently, February is the cheapest month in which you can book a flight from Greenville to Medellín (average of $270). Flying from Greenville to Medellín in June is currently the most expensive (average of $492). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.

See more FAQs

Browse thousands of different options on Cheapflights for your next trip

Toggle through the tabs below to find thousands of options on Cheapflights for your next trip.

Alternative routes for Greenville to Medellín

See prices for flight routes from nearby airports that may be better suited for you.
Charlotte to Jose Maria Cordova Intl flights
Charlotte to Bogotá flights
Charlotte to Cartagena flights
Charlotte to Cali flights
Charleston to Jose Maria Cordova Intl flights
Greenville to Bogotá flights
Greenville to Pereira flights
Charlotte to Barranquilla flights
Savannah to Bogotá flights
Charleston to Bogotá flights
Charlotte to San Andrés flights
Greenville to Jose Maria Cordova Intl flights
Charlotte to Pereira flights
Charleston to Cartagena flights
Charlotte to Armenia flights
Columbia to Barranquilla flights
Savannah to Jose Maria Cordova Intl flights
Savannah to Cartagena flights
Myrtle Beach to Jose Maria Cordova Intl flights
Greenville to Cartagena flights
Myrtle Beach to Bogotá flights
Charlotte to Cúcuta flights
Columbia to Cartagena flights
Myrtle Beach to Cartagena flights
Myrtle Beach to Cali flights
Augusta to Bogotá flights
Myrtle Beach to Armenia flights
Charlotte to Santa Marta flights
Greenville to Santa Marta flights
Charleston to Cúcuta flights
Charlotte to Manizales flights

Top 2 airlines flying from Greenville to Medellín

Discover the top 2 airlines that operate flights from Greenville to Medellín. Compare their services, reliability, and customer satisfaction ratings to choose the airline that best suits your travel preferences and needs. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated January 27, 2026.
AirlineCheapestAverageFlexibilityOn-time
American AirlinesCheapest$515Average$740FlexibilityNo cancel feeOn-time71%
LATAM AirlinesCheapest$670Average$776FlexibilityNo cancel feeOn-time81%

100% Free

Cheapflights is completely free to use, so you can start saving the moment you arrive.

Book with Flexibility

Our users can plan ahead with confidence and find flights with no change fees

Travel Smart

Millions of people come to us for their flight needs every year. We help make travel planning easy by providing useful insights and data-driven graphs that can inform your decisions.