Question 1

What are the cheapest airlines flying from Des Moines to Medellín round-trip?

Accepted Answer

Our cheapest airline available from Des Moines to Medellín is United Airlines. Our recent data shows that you can find tickets from as low as $585 on this airline. An additional option worth looking into is American Airlines, starting at $591.

Question 2

What is the cheapest month to book a flight from Des Moines to Medellín?

Accepted Answer

Currently, January is the cheapest month in which you can book a flight from Des Moines to Medellín (average of $378). Flying from Des Moines to Medellín in December is currently the most expensive (average of $625). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.

Question 3

What is the cheapest day to fly from Des Moines to Medellín?

Accepted Answer

Travelers seeking maximum savings on their Des Moines to Medellín flight should consider departing on Saturday mornings when fares are most often at their lowest. Saturday mornings flights should be avoided if possible as fares are typically the most expensive at this time.

Question 4

E

Accepted Answer

In terms of precipitation, rainfall in Medellín ranges from 2.0 - 7.9 inches per month. October is typically the wettest month, when rainfall can reach 7.9 in. January is typically the driest time to visit Medellín when rainfall is around 2.0 in.

Question 5

E

Accepted Answer

If weather is an important factor for your trip to Medellín, use this chart to help with planning. For those seeking warmer temperatures, January is the ideal time of year to visit, when temperatures reach an average of 71.6 F. Travelers looking to avoid the cold should look outside of October, when temperatures are typically at their lowest (around 69.8 F).

Question 6

What is the cheapest time of day to fly from DSM to MDE?

Accepted Answer

A simple way to save on the total cost of your ticket is to fly from Des Moines to Medellín at noon. If you’re flexible enough to do this you can expect to save up to 31% on your trip compared to booking a flight in the morning.

Question 7

What airport do you fly from for flights from Des Moines to Medellín?

Accepted Answer

If you book a flight to Medellín from Des Moines, you will be flying from Des Moines, which is the city’s only airport. Des Moines (DSM) is located 3.6 mi from the center of Des Moines. There are 0 flights from Des Moines to Medellín per day from 2 different airlines.

Question 8

Can I find deals for flights from Des Moines to Medellín that include hotel bookings?

Accepted Answer

Yes. In addition to deals on Des Moines to Medellín flights, Cheapflights offers vacation packages that include both flights and hotel.

Question 9

How can I find direct flights from Des Moines to Medellín?

Accepted Answer

After entering your origin and destination, apply the non-stop filter on the search result page to find direct flights from Des Moines to Medellín.

Question 10

Can I find deals for business class flights from Des Moines to Medellín?

Accepted Answer

Yes. Cheapflights offers flight deals from Des Moines to Medellín by cabin class. In addition to browsing deals, you can also filter by cabin class on the search results page after making a search.

Airline	Cheapest	Average	Flexibility	On-time
United Airlines	Cheapest$585	Average$706	FlexibilityNo cancel fee	On-time69%
American Airlines	Cheapest$591	Average$769	FlexibilityNo cancel fee	On-time71%

Find cheap flights from Des Moines to Medellín with Cheapflights

1. Tell us where you want to go

2. Select your favorite providers

3. Compare prices and book

Best time to book a flight from Des Moines to Medellín

Have a flexible travel schedule? Discover the best time to fly to Medellín from Des Moines with our price prediction graph.

Cheapflights Insights

Everything you need to know about your flight from Des Moines to Medellín

What is the cheapest time of day to fly from DSM to MDE?

Reviews of airlines servicing Medellín

Read through reviews of airlines operating flights from Des Moines to Medellín, such as United Airlines and American Airlines. You can also see how each airline stacks up in terms of entertainment options, comfort, food, crew/service, and boarding process.

Related info for your journey

Find useful and relevant information for your journey from Des Moines to Medellín. Access travel guides, tips, and recommendations to enhance your travel experience. Get information about local attractions, weather, transportation options, and more.

What airport do you fly from for flights from Des Moines to Medellín?

What are the cheapest airlines flying from Des Moines to Medellín round-trip?

Can I find deals for flights from Des Moines to Medellín that include hotel bookings?

How can I find direct flights from Des Moines to Medellín?

Can I find deals for business class flights from Des Moines to Medellín?

What is the cheapest month to book a flight from Des Moines to Medellín?

Browse thousands of different options on Cheapflights for your next trip

Toggle through the tabs below to find thousands of options on Cheapflights for your next trip.

Alternative routes for Des Moines to Medellín

See prices for flight routes from nearby airports that may be better suited for you.

Complete your trip

Complete your trip to Medellín by adding a car rental and/or hotel reservation to your travel itinerary.

Search flights from Des Moines to Medellín by cabin class

Find flights from Des Moines to Medellín, based on your preferred cabin class, be it economy, premium economy, business, or first class.

Des Moines and Medellín flights

Browse other Des Moines and Medellín flight options. Last updated on August 26, 2025.

Other flights from Des Moines

Browse through other flights departing from Des Moines. Flights are based on user searches made on Cheapflights and were last updated on August 26, 2025.

Popular flight searches

Check out other popular destinations found by fellow travelers in 2025

Top 2 airlines flying from Des Moines to Medellín

100% Free

Book with Flexibility

Travel Smart

Cheap flights from Des Moines (DSM) to Medellín

Find cheap flights from Des Moines to Medellín with Cheapflights

1. Tell us where you want to go

2. Select your favorite providers

3. Compare prices and book

Best time to book a flight from Des Moines to Medellín

Have a flexible travel schedule? Discover the best time to fly to Medellín from Des Moines with our price prediction graph.

Cheapflights Insights

Everything you need to know about your flight from Des Moines to Medellín

What is the cheapest time of day to fly from DSM to MDE?

Reviews of airlines servicing Medellín

Read through reviews of airlines operating flights from Des Moines to Medellín, such as United Airlines and American Airlines. You can also see how each airline stacks up in terms of entertainment options, comfort, food, crew/service, and boarding process.

Related info for your journey

Find useful and relevant information for your journey from Des Moines to Medellín. Access travel guides, tips, and recommendations to enhance your travel experience. Get information about local attractions, weather, transportation options, and more.

What airport do you fly from for flights from Des Moines to Medellín?

What are the cheapest airlines flying from Des Moines to Medellín round-trip?

Can I find deals for flights from Des Moines to Medellín that include hotel bookings?

How can I find direct flights from Des Moines to Medellín?

Can I find deals for business class flights from Des Moines to Medellín?

What is the cheapest month to book a flight from Des Moines to Medellín?

Browse thousands of different options on Cheapflights for your next trip

Toggle through the tabs below to find thousands of options on Cheapflights for your next trip.

Alternative routes for Des Moines to Medellín

See prices for flight routes from nearby airports that may be better suited for you.

Top 2 airlines flying from Des Moines to Medellín

100% Free

Book with Flexibility

Travel Smart