$228+ Cheap flights from Charlotte (CLT) to Medellín
This is the cheapest round-trip flight price found by a Cheapflights user in the last 72 hours by searching for a flight departing on 1/16. Fares are subject to change and may not be available on all flights or dates of travel.
CLT — MDE
Nov 29 — Dec 61
Round-trip
1 adult, Economy
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Find cheap flights from Charlotte to Medellín with Cheapflights
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Enter your travel information like dates, passengers, trip type (one-way or round trip), and preferred cabin class then click “Find deals”2. Select your favorite providers
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Cheapest flights from Charlotte to MedellínExplore the most affordable flight options available from Charlotte to Medellín. Find the lowest fares from popular airlines and budget airlines, with prices last updated on October 30, 2026.
Explore the most affordable flight options available from Charlotte to Medellín. Find the lowest fares from popular airlines and budget airlines, with prices last updated on October 30, 2026.
This Frontier deal was found by Cheapflights users on 10/27. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Frontier is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 12/114:02 pm -
1 stop19h 58m
Sat 12/191:10 pm -
1 stop11h 33m
Deal found 10/27![Frontier logo]()
$505
This Mytrip deal was found by Cheapflights users on 10/27. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Mytrip is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 11/139:41 pm -
1 stop10h 44m
Wed 11/185:50 pm -
2 stops27h 43m
Deal found 10/27![Multiple Airlines logo]()
$513
This Mytrip deal was found by Cheapflights users on 10/29. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Mytrip is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 11/99:41 pm -
2 stops16h 09m
Sun 11/158:40 pm -
2 stops24h 06m
Deal found 10/29![Multiple Airlines logo]()
$524
This FlightHub deal was found by Cheapflights users on 10/28. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure FlightHub is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 12/93:34 pm -
1 stop20h 26m
Tue 12/151:10 pm -
1 stop10h 39m
Deal found 10/28![Frontier logo]()
$545
This Mytrip deal was found by Cheapflights users on 10/25. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Mytrip is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 11/110:18 pm -
2 stops34h 07m
Wed 11/49:05 pm -
2 stops24h 28m
Deal found 10/25![Multiple Airlines logo]()
$555
This FlightHub deal was found by Cheapflights users on 10/27. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure FlightHub is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 12/93:34 pm -
1 stop20h 26m
Sun 12/131:10 pm -
1 stop26h 10m
Deal found 10/27![Frontier logo]()
$575
This FlightHub deal was found by Cheapflights users on 10/28. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure FlightHub is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 12/104:22 pm -
1 stop19h 38m
Mon 12/211:10 pm -
1 stop11h 33m
Deal found 10/28![Frontier logo]()
$576
This Justfly.com deal was found by Cheapflights users on 10/26. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Justfly.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 12/301:28 pm -
1 stop22h 32m
Tue 2/231:10 pm -
1 stop11h 11m
Deal found 10/26![Frontier logo]()
$591
This Priceline deal was found by Cheapflights users on 10/29. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Priceline is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 12/134:22 pm -
1 stop19h 38m
Sun 12/201:10 pm -
1 stop25h 22m
Deal found 10/29![Frontier logo]()
$594
Best flights from Charlotte to MedellínDiscover carefully curated flight deals from Charlotte to Medellín that have cost, travel time, and layovers in mind to ensure you get the best travel experience. Data last updated October 30, 2026.
Discover carefully curated flight deals from Charlotte to Medellín that have cost, travel time, and layovers in mind to ensure you get the best travel experience. Data last updated October 30, 2026.
This Copa Airlines deal was found by Cheapflights users on 10/27. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Copa Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 12/47:50 pm -
2 stops21h 10m
Wed 12/912:40 pm -
2 stops21h 42m
Deal found 10/27![Copa Airlines logo]()
$661
This United Airlines deal was found by Cheapflights users on 10/25. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 11/177:55 pm -
2 stops26h 15m
Mon 11/2310:40 am -
1 stop11h 19m
Deal found 10/25![United Airlines logo]()
$713
This JetBlue deal was found by Cheapflights users on 10/26. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure JetBlue is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 12/59:00 am -
1 stop6h 55m
Thu 12/172:25 pm -
1 stop8h 34m
Deal found 10/26![JetBlue logo]()
$731
This Copa Airlines deal was found by Cheapflights users on 10/26. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Copa Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 12/97:50 pm -
2 stops27h 00m
Tue 12/159:15 am -
2 stops25h 07m
Deal found 10/26![Copa Airlines logo]()
$667
This United Airlines deal was found by Cheapflights users on 10/29. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 2/16:30 am -
1 stop15h 40m
Fri 2/510:40 am -
1 stop11h 28m
Deal found 10/29![United Airlines logo]()
$724
This Copa Airlines deal was found by Cheapflights users on 10/25. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Copa Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 11/176:00 am -
2 stops26h 15m
Mon 11/2310:45 am -
2 stops23h 57m
Deal found 10/25![Copa Airlines logo]()
$671
This United Airlines deal was found by Cheapflights users on 10/28. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 1/245:08 pm -
2 stops29h 02m
Sun 2/710:40 am -
1 stop11h 28m
Deal found 10/28![United Airlines logo]()
$728
This Copa Airlines deal was found by Cheapflights users on 10/30. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Copa Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 2/197:55 pm -
2 stops18h 50m
Sat 2/276:20 pm -
2 stops16h 16m
Deal found 10/30![Copa Airlines logo]()
$691
This Copa Airlines deal was found by Cheapflights users on 10/27. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Copa Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 11/196:00 am -
2 stops26h 15m
Mon 11/236:25 pm -
2 stops16h 17m
Deal found 10/27![Copa Airlines logo]()
$762
Last-minute flights from Charlotte to MedellínDiscover last-minute flight deals from Charlotte to Medellín. Data last updated October 30, 2026 and is based on user searches.
Discover last-minute flight deals from Charlotte to Medellín. Data last updated October 30, 2026 and is based on user searches.
This Mytrip deal was found by Cheapflights users on 10/25. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Mytrip is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 11/110:18 pm -
2 stops34h 07m
Wed 11/49:05 pm -
2 stops24h 28m
Deal found 10/25![Multiple Airlines logo]()
$555
This Mytrip deal was found by Cheapflights users on 10/27. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Mytrip is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 11/29:41 pm -
2 stops21h 44m
Sat 11/78:40 pm -
2 stops24h 53m
Deal found 10/27![Multiple Airlines logo]()
$625
This Mytrip deal was found by Cheapflights users on 10/25. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Mytrip is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 11/25:38 pm -
3 stops29h 42m
Fri 11/611:25 am -
2 stops23h 15m
Deal found 10/25![Multiple Airlines logo]()
$633
This Mytrip deal was found by Cheapflights users on 10/28. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Mytrip is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 11/711:37 am -
2 stops20h 48m
Sun 11/158:40 pm -
2 stops24h 06m
Deal found 10/28![Multiple Airlines logo]()
$624
This Mytrip deal was found by Cheapflights users on 10/26. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Mytrip is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 11/711:37 am -
2 stops20h 48m
Fri 11/2012:10 am -
1 stop16h 55m
Deal found 10/26![Multiple Airlines logo]()
$661
This Mytrip deal was found by Cheapflights users on 10/29. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Mytrip is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 11/99:41 pm -
2 stops16h 09m
Sun 11/158:40 pm -
2 stops24h 06m
Deal found 10/29![Multiple Airlines logo]()
$524
This Kiwi.com deal was found by Cheapflights users on 10/27. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 11/116:05 am -
1 stop17h 05m
Wed 12/26:25 pm -
2 stops28h 47m
Deal found 10/27![Multiple Airlines logo]()
$644
This Mytrip deal was found by Cheapflights users on 10/27. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Mytrip is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 11/139:41 pm -
1 stop10h 44m
Wed 11/185:50 pm -
2 stops27h 43m
Deal found 10/27![Multiple Airlines logo]()
$513
This Kiwi.com deal was found by Cheapflights users on 10/25. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 11/236:01 pm -
1 stop14h 24m
Wed 12/26:25 pm -
2 stops28h 47m
Deal found 10/25![Multiple Airlines logo]()
$618
One-way flights from Charlotte to MedellínSearch for one-way flight options from Charlotte to Medellín. Find affordable one-way fares based on user searches. Data last updated October 30, 2026.
Search for one-way flight options from Charlotte to Medellín. Find affordable one-way fares based on user searches. Data last updated October 30, 2026.
This FlightHub deal was found by Cheapflights users on 10/26. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure FlightHub is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 1/163:36 pm -
1 stop20h 24m
Wed 12/3112:00 am -
Nonstop0h 00m
Deal found 10/26![Frontier logo]()
$228
This Kiwi.com deal was found by Cheapflights users on 10/26. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 12/88:59 am -
3 stops47h 16m
Wed 12/3112:00 am -
Nonstop0h 00m
Deal found 10/26![Multiple Airlines logo]()
$234
This Priceline deal was found by Cheapflights users on 10/27. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Priceline is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 1/11:28 pm -
1 stop22h 32m
Wed 12/3112:00 am -
Nonstop0h 00m
Deal found 10/27![Frontier logo]()
$235
This Kiwi.com deal was found by Cheapflights users on 10/26. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 11/810:18 pm -
3 stops45h 19m
Wed 12/3112:00 am -
Nonstop0h 00m
Deal found 10/26![Multiple Airlines logo]()
$237
This Kiwi.com deal was found by Cheapflights users on 10/26. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 11/1210:18 pm -
2 stops33h 57m
Wed 12/3112:00 am -
Nonstop0h 00m
Deal found 10/26![Multiple Airlines logo]()
$238
This Kiwi.com deal was found by Cheapflights users on 10/26. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 11/510:18 pm -
2 stops21h 22m
Wed 12/3112:00 am -
Nonstop0h 00m
Deal found 10/26![Multiple Airlines logo]()
$239
This Kiwi.com deal was found by Cheapflights users on 10/29. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 11/99:41 pm -
3 stops58h 34m
Wed 12/3112:00 am -
Nonstop0h 00m
Deal found 10/29![Multiple Airlines logo]()
$251
This Kiwi.com deal was found by Cheapflights users on 10/29. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 11/106:05 am -
3 stops26h 10m
Wed 12/3112:00 am -
Nonstop0h 00m
Deal found 10/29![Multiple Airlines logo]()
$258
Find flight deals from Charlotte to Medellín
Discover tips and strategies to find the most affordable flight options for your journey from Charlotte (CLT) to Medellín (CO1). Learn about various techniques such as flexible date searches, comparing prices across and setting up price alerts. Use these methods to find the cheapest flights available for your travel needs. Data last updated October 30, 2026.
Round-trip from | $505 (Frontier) |
|---|---|
One-way from | $228 (FlightHub) |
Popular in | October |
Cheapest in | February |
Average price | $921 |
Cheapflights Fare Finder
Customize your flight search to find flights from Charlotte to Medellín that fit within your specific budget. Explore options based on user searches and filter the results based on your desired price range. Find flights that match your budget for a cost-effective journey. Over the last 7 days, Cheapflights users made 7,457,451 searches. Data last updated October 30, 2026.
Use the filters below to find and compare flights from Charlotte to Medellín that are best for you.
Fly from
Fly to
Route
Depart
Return
Cheapest round-trip
CharlotteMedellín
CLT Charlotte Douglas - MDE Medellín Jose Maria Cordova Intl
CLTMDE
Charlotte Douglas
Sat 1/23
3:36 pm-12:00 pm
1 stop20h 24m
Medellín Jose Maria Cordova Intl
Wed 12/31
12:00 am-12:00 am
Nonstop0h 00m
$235
CharlotteMedellín
CLT Charlotte Douglas - MDE Medellín Jose Maria Cordova Intl
CLTMDE
Charlotte Douglas
Sat 1/23
7:40 pm-8:35 pm
2 stops24h 55m
Medellín Jose Maria Cordova Intl
Wed 12/31
12:00 am-12:00 am
Nonstop0h 00m
$300
CharlotteMedellín
CLT Charlotte Douglas - MDE Medellín Jose Maria Cordova Intl
CLTMDE
Charlotte Douglas
Thu 2/18
9:55 am-2:15 pm
2 stops28h 20m
Medellín Jose Maria Cordova Intl
Wed 12/31
12:00 am-12:00 am
Nonstop0h 00m
$300
Quickest round-trip
CharlotteMedellín
CLT Charlotte Douglas - MDE Medellín Jose Maria Cordova Intl
CLTMDE
Charlotte Douglas
Tue 1/19
12:01 pm-10:50 pm
2 stops10h 49m
Medellín Jose Maria Cordova Intl
Wed 12/31
12:00 am-12:00 am
Nonstop0h 00m
$302
CharlotteMedellín
CLT Charlotte Douglas - MDE Medellín Jose Maria Cordova Intl
CLTMDE
Charlotte Douglas
Mon 12/21
7:50 pm-2:15 pm
2 stops18h 25m
Medellín Jose Maria Cordova Intl
Wed 12/31
12:00 am-12:00 am
Nonstop0h 00m
$304
CharlotteMedellín
CLT Charlotte Douglas - MDE Medellín Jose Maria Cordova Intl
CLTMDE
Charlotte Douglas
Wed 1/20
7:40 pm-10:10 pm
2 stops26h 30m
Medellín Jose Maria Cordova Intl
Wed 12/31
12:00 am-12:00 am
Nonstop0h 00m
$310
CharlotteMedellín
CLT Charlotte Douglas - MDE Medellín Jose Maria Cordova Intl
CLTMDE
Charlotte Douglas
Sun 1/31
7:02 am-9:25 pm
1 stop14h 23m
Medellín Jose Maria Cordova Intl
Wed 12/31
12:00 am-12:00 am
Nonstop0h 00m
$310
CharlotteMedellín
CLT Charlotte Douglas - MDE Medellín Jose Maria Cordova Intl
CLTMDE
Charlotte Douglas
Fri 12/4
7:50 pm-5:00 pm
2 stops21h 10m
Medellín Jose Maria Cordova Intl
Wed 12/9
12:40 pm-10:22 am
2 stops21h 42m
$661
CharlotteMedellín
CLT Charlotte Douglas - MDE Medellín Jose Maria Cordova Intl
CLTMDE
Charlotte Douglas
Wed 12/9
7:50 pm-10:50 pm
2 stops27h 00m
Medellín Jose Maria Cordova Intl
Tue 12/15
9:15 am-10:22 am
2 stops25h 07m
$667
CharlotteMedellín
CLT Charlotte Douglas - MDE Medellín Jose Maria Cordova Intl
CLTMDE
Charlotte Douglas
Tue 11/17
6:00 am-8:15 am
2 stops26h 15m
Medellín Jose Maria Cordova Intl
Mon 11/23
10:45 am-10:42 am
2 stops23h 57m
$671
Showing 1-10 of 16 resultsSorted by cheapest first
Best time to book a flight from Charlotte to Medellín
Have a flexible travel schedule? Discover the best time to fly to Medellín from Charlotte with our price prediction graph.
CLT-CO1
CLT-MDE
Estimated round-trip price
Rates are based on past data. Find the cheapest month and day to book your flight based on your travel requirements, then search for cheap deals.
Cheapflights Insights
Everything you need to know about your flight from Charlotte to Medellín
CLT-CO1
CLT-MDE
What is the cheapest month to book a flight from Charlotte to Medellín?
Currently, February is the cheapest month in which you can book a flight from Charlotte to Medellín (average of $364). Flying from Charlotte to Medellín in October is currently the most expensive (average of $921). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.
How much does it cost to fly round-trip from Charlotte to Medellín?
Airfare is typical for this route at the moment.
Charlotte to Medellín flights typically cost between $472 and $689 in December.The cheapest round-trip price found within the last 5 days was $505 on Frontier (Dec 11-Dec 19).
How far ahead should I book a flight from Charlotte to Medellín?
The price you pay for your flight from Charlotte to Medellín may vary depending on when you book. For the best chance of a lower fare, look to book 52 days in advance of your trip. Fares are likely to increase a fortnight or so before your departure date.
Reviews of airlines servicing Medellín
Get insights into the airlines that provide service to Medellín. Read reviews, discover amenities, and learn about the overall travel experience offered by airlines. Use this information to make informed decisions when choosing an airline for your flight to Medellín. Reviews last updated October 30, 2026.
Read through reviews of airlines operating flights from Charlotte to Medellín, such as GOL,JetBlue, andAmerican Airlines. Reviews also offer insight into each airline's entertainment options, comfort, food, crew/service, and boarding process.
Boarding
7.3
Crew
8.2
Entertainment
6.2
Food
6.0
Overall
7.3
Comfort
7.1
Reviews
1 / 11
2.0
MediocreAnonymous,Sep 2026
MIA - LAX
Boarding
7.3
Crew
8.2
Entertainment
6.2
Food
6.0
Overall
7.3
Comfort
7.1
Reviews
1 / 11
2.0
MediocreAnonymous,Sep 2026
MIA - LAX
Boarding
7.3
Crew
8.2
Entertainment
6.2
Food
6.0
Overall
7.3
Comfort
7.1
Reviews
1 / 11
2.0
MediocreAnonymous,Sep 2026
MIA - LAX
Boarding
7.3
Crew
8.2
Entertainment
6.2
Food
6.0
Overall
7.3
Comfort
7.1
Reviews
1 / 11
2.0
MediocreAnonymous,Sep 2026
MIA - LAX
Related info for your journey
Find useful and relevant information for your journey from Charlotte to Medellín. Access travel guides, tips, and recommendations to enhance your travel experience. Get information about local attractions, weather, transportation options, and more.
Browse thousands of different options on Cheapflights for your next trip
Toggle through the tabs below to find thousands of options on Cheapflights for your next trip.
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Alternative routes for Charlotte to Medellín
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Complete your trip
Complete your trip to Medellín by adding a car rental and/or hotel reservation to your travel itinerary.
Search flights from Charlotte to Medellín by cabin class
Find flights from Charlotte to Medellín, based on your preferred cabin class, be it economy, premium economy, business, or first class.
Charlotte and Medellín flights
Browse other Charlotte and Medellín flight options. Last updated on October 30, 2026.
Other flights from Charlotte
Browse through other flights departing from Charlotte. Flights are based on user searches made on Cheapflights and were last updated on October 30, 2026.
Popular flight searches
Check out other popular destinations found by fellow travelers in 2026
Top 4 airlines flying from Charlotte to Medellín
Discover the top 4 airlines that operate flights from Charlotte to Medellín. Compare their services, reliability, and customer satisfaction ratings to choose the airline that best suits your travel preferences and needs. Over the last 7 days, Cheapflights users made 7,457,451 searches. Data last updated October 30, 2026.
| Airline | Cheapest | Average | Flexibility | On-time |
|---|---|---|---|---|
| Cheapest$449 | Average$738 | FlexibilityNo cancel fee | On-time71% | |
| Cheapest$472 | Average$647 | FlexibilityNo cancel fee | On-time62% | |
| Cheapest$528 | Average$703 | FlexibilityNo cancel fee | On-time70% | |
| Cheapest$581 | Average$950 | FlexibilityNo cancel fee | On-time74% |