$771+ Cheap flights from Knoxville (TYS) to Manchester (MAN)
This is the cheapest round-trip flight price found by a Cheapflights user in the last 72 hours by searching for a flight departing on 9/28. Fares are subject to change and may not be available on all flights or dates of travel.
TYS — MAN
Oct 11 — Oct 181
Round-trip
1 adult, Economy
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Find cheap flights from Knoxville to Manchester with Cheapflights
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Enter your travel information like dates, passengers, trip type (one-way or round trip), and preferred cabin class then click “Find deals”2. Select your favorite providers
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Best
Last-minute
Cheapest flights from Knoxville to ManchesterExplore the most affordable flight options available from Knoxville to Manchester. Find the lowest fares from popular airlines and budget airlines, with prices last updated on September 11, 2026.
Explore the most affordable flight options available from Knoxville to Manchester. Find the lowest fares from popular airlines and budget airlines, with prices last updated on September 11, 2026.
This Delta deal was found by Cheapflights users on 9/10. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 9/287:50 am -
1 stop20h 00m
Thu 10/151:00 pm -
1 stop14h 08m
Deal found 9/10![Delta logo]()
$771
This Delta deal was found by Cheapflights users on 9/10. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 9/298:55 am -
2 stops19h 45m
Wed 10/1412:10 pm -
2 stops15h 12m
Deal found 9/10![Delta logo]()
$775
This Delta deal was found by Cheapflights users on 9/10. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 9/287:50 am -
1 stop20h 00m
Wed 10/1410:40 am -
1 stop27h 54m
Deal found 9/10![Delta logo]()
$776
This Air France deal was found by Cheapflights users on 9/10. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Air France is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 9/286:13 pm -
2 stops14h 47m
Fri 10/161:00 pm -
1 stop15h 59m
Deal found 9/10![Multiple Airlines logo]()
$790
This Delta deal was found by Cheapflights users on 9/10. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 9/2812:23 pm -
2 stops16h 37m
Tue 10/1312:10 pm -
2 stops15h 12m
Deal found 9/10![Delta logo]()
$795
This Delta deal was found by Cheapflights users on 9/10. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 10/2512:06 pm -
1 stop14h 34m
Sun 11/111:00 am -
1 stop14h 08m
Deal found 9/10![Delta logo]()
$808
This Delta deal was found by Cheapflights users on 9/10. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 9/287:50 am -
1 stop20h 00m
Sun 10/1811:15 am -
1 stop17h 44m
Deal found 9/10![Delta logo]()
$821
This Delta deal was found by Cheapflights users on 9/10. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 9/292:08 pm -
2 stops14h 32m
Mon 10/1212:10 pm -
2 stops16h 49m
Deal found 9/10![Delta logo]()
$825
This Delta deal was found by Cheapflights users on 9/10. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 9/2812:23 pm -
1 stop15h 27m
Sat 10/171:15 pm -
1 stop31h 57m
Deal found 9/10![Delta logo]()
$826
This Delta deal was found by Cheapflights users on 9/10. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 9/2912:23 pm -
2 stops16h 17m
Sat 10/171:15 pm -
1 stop31h 57m
Deal found 9/10![Delta logo]()
$831
Best flights from Knoxville to ManchesterDiscover carefully curated flight deals from Knoxville to Manchester that have cost, travel time, and layovers in mind to ensure you get the best travel experience. Data last updated September 11, 2026.
Discover carefully curated flight deals from Knoxville to Manchester that have cost, travel time, and layovers in mind to ensure you get the best travel experience. Data last updated September 11, 2026.
This Delta deal was found by Cheapflights users on 9/10. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 9/2212:23 pm -
2 stops16h 17m
Wed 10/712:10 pm -
2 stops15h 12m
Deal found 9/10![Delta logo]()
$775
This United Airlines deal was found by Cheapflights users on 9/10. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 1/76:15 am -
3 stops45h 45m
Thu 1/1411:30 am -
2 stops41h 35m
Deal found 9/10![United Airlines logo]()
$866
This Delta deal was found by Cheapflights users on 9/10. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 10/259:12 am -
1 stop17h 28m
Sun 11/12:55 pm -
2 stops24h 50m
Deal found 9/10![Delta logo]()
$813
This United Airlines deal was found by Cheapflights users on 9/10. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 11/610:43 am -
2 stops18h 37m
Sat 11/146:10 am -
2 stops18h 26m
Deal found 9/10![United Airlines logo]()
$881
This Delta deal was found by Cheapflights users on 9/10. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 1/75:57 pm -
1 stop11h 53m
Thu 1/142:55 pm -
1 stop13h 51m
Deal found 9/10![Delta logo]()
$817
This Delta deal was found by Cheapflights users on 9/10. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 9/2812:23 pm -
2 stops16h 37m
Sat 10/171:15 pm -
1 stop31h 57m
Deal found 9/10![Delta logo]()
$846
This Delta deal was found by Cheapflights users on 9/9. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 11/62:38 pm -
2 stops20h 27m
Sat 11/1412:40 pm -
1 stop14h 32m
Deal found 9/9![Delta logo]()
$878
This Delta deal was found by Cheapflights users on 9/9. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 11/2012:34 pm -
1 stop16h 56m
Sun 11/292:55 pm -
2 stops24h 00m
Deal found 9/9![Delta logo]()
$1,071
Last-minute flights from Knoxville to ManchesterDiscover last-minute flight deals from Knoxville to Manchester. Data last updated September 11, 2026 and is based on user searches.
Discover last-minute flight deals from Knoxville to Manchester. Data last updated September 11, 2026 and is based on user searches.
This Delta deal was found by Cheapflights users on 9/10. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 9/287:50 am -
1 stop20h 00m
Thu 10/151:00 pm -
1 stop14h 08m
Deal found 9/10![Delta logo]()
$771
This Delta deal was found by Cheapflights users on 9/10. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 9/287:50 am -
1 stop20h 00m
Wed 10/1410:40 am -
1 stop27h 54m
Deal found 9/10![Delta logo]()
$776
This Air France deal was found by Cheapflights users on 9/10. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Air France is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 9/286:13 pm -
2 stops14h 47m
Fri 10/161:00 pm -
1 stop15h 59m
Deal found 9/10![Multiple Airlines logo]()
$790
This Delta deal was found by Cheapflights users on 9/10. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 9/2812:23 pm -
2 stops16h 37m
Tue 10/1312:10 pm -
2 stops15h 12m
Deal found 9/10![Delta logo]()
$795
This Delta deal was found by Cheapflights users on 9/10. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 9/287:50 am -
1 stop20h 00m
Sun 10/1811:15 am -
1 stop17h 44m
Deal found 9/10![Delta logo]()
$821
This Delta deal was found by Cheapflights users on 9/10. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 9/2812:23 pm -
1 stop15h 27m
Sat 10/171:15 pm -
1 stop31h 57m
Deal found 9/10![Delta logo]()
$826
This Delta deal was found by Cheapflights users on 9/10. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 9/298:55 am -
2 stops19h 45m
Wed 10/1412:10 pm -
2 stops15h 12m
Deal found 9/10![Delta logo]()
$775
This Delta deal was found by Cheapflights users on 9/10. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 9/292:08 pm -
2 stops14h 32m
Mon 10/1212:10 pm -
2 stops16h 49m
Deal found 9/10![Delta logo]()
$825
This Delta deal was found by Cheapflights users on 9/10. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 9/2912:23 pm -
2 stops16h 17m
Sat 10/171:15 pm -
1 stop31h 57m
Deal found 9/10![Delta logo]()
$831
This Delta deal was found by Cheapflights users on 9/10. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 10/2512:06 pm -
1 stop14h 34m
Sun 11/111:00 am -
1 stop14h 08m
Deal found 9/10![Delta logo]()
$808
Find flight deals from Knoxville to Manchester
Discover tips and strategies to find the most affordable flight options for your journey from Knoxville (TYS) to Manchester (MAN). Learn about various techniques such as flexible date searches, comparing prices across and setting up price alerts. Use these methods to find the cheapest flights available for your travel needs. Data last updated September 11, 2026.
Most accurate provider | FlightHub 3 stars |
|---|---|
Most trusted provider | FlightHub 3 stars |
Round-trip from | $771 (Delta) |
Popular in | May |
Cheapest in | January |
Average price | $1,030 |
Cheapflights Fare Finder
Customize your flight search to find flights from Knoxville to Manchester that fit within your specific budget. Explore options based on user searches and filter the results based on your desired price range. Find flights that match your budget for a cost-effective journey. Over the last 7 days, Cheapflights users made 7,457,451 searches. Data last updated September 11, 2026.
Use the filters below to find and compare flights from Knoxville to Manchester that are best for you.
Fly from
Fly to
Route
Depart
Return
Cheapest round-trip
KnoxvilleManchester
TYS Knoxville McGhee Tyson - MAN Manchester
TYSMAN
Knoxville McGhee Tyson
Tue 9/22
12:23 pm-9:40 am
2 stops16h 17m
Manchester
Wed 10/7
12:10 pm-10:22 pm
2 stops15h 12m
$775
KnoxvilleManchester
TYS Knoxville McGhee Tyson - MAN Manchester
TYSMAN
Knoxville McGhee Tyson
Sun 10/25
9:12 am-6:40 am
1 stop17h 28m
Manchester
Sun 11/1
2:55 pm-10:45 am
2 stops24h 50m
$813
Quickest round-trip
KnoxvilleManchester
TYS Knoxville McGhee Tyson - MAN Manchester
TYSMAN
Knoxville McGhee Tyson
Thu 1/7
5:57 pm-10:50 am
1 stop11h 53m
Manchester
Thu 1/14
2:55 pm-11:46 pm
1 stop13h 51m
$817
KnoxvilleManchester
TYS Knoxville McGhee Tyson - MAN Manchester
TYSMAN
Knoxville McGhee Tyson
Mon 9/28
12:23 pm-10:00 am
2 stops16h 37m
Manchester
Sat 10/17
1:15 pm-4:12 pm
1 stop31h 57m
$846
KnoxvilleManchester
TYS Knoxville McGhee Tyson - MAN Manchester
TYSMAN
Knoxville McGhee Tyson
Thu 1/7
6:15 am-9:00 am
3 stops45h 45m
Manchester
Thu 1/14
11:30 am-12:05 am
2 stops41h 35m
$866
KnoxvilleManchester
TYS Knoxville McGhee Tyson - MAN Manchester
TYSMAN
Knoxville McGhee Tyson
Fri 11/6
2:38 pm-4:05 pm
2 stops20h 27m
Manchester
Sat 11/14
12:40 pm-10:12 pm
1 stop14h 32m
$878
KnoxvilleManchester
TYS Knoxville McGhee Tyson - MAN Manchester
TYSMAN
Knoxville McGhee Tyson
Fri 11/6
10:43 am-10:20 am
2 stops18h 37m
Manchester
Sat 11/14
6:10 am-7:36 pm
2 stops18h 26m
$881
KnoxvilleManchester
TYS Knoxville McGhee Tyson - MAN Manchester
TYSMAN
Knoxville McGhee Tyson
Fri 11/20
12:34 pm-10:30 am
1 stop16h 56m
Manchester
Sun 11/29
2:55 pm-9:55 am
2 stops24h 00m
$1,071
Sorted by cheapest first
Compare providers for flights from Knoxville to Manchester
Provider information is updated monthly. Please note that these providers often have deals for this flight, but the availability may vary on a day-by-day basis on Cheapflights.
Use the table below to compare price accuracy, trust ratings, and cancellation policies for each provider offering flight deals from Knoxville to Manchester in September.
| Provider | Price Accuracy | Trust Score* |
|---|---|---|
| Price Accuracy1 star | Trust Score*3 stars | |
| Price Accuracy3 stars | Trust Score*3 stars | |
| Price Accuracy3 stars | Trust Score*3 stars | |
| Price Accuracy3 stars | Trust Score*3 stars |
- Most accurate provider: When it comes to deals on Knoxville-Manchester flights, users find the pricing of FlightHub to be most consistent on Cheapflights vs. FlightHub Users can find the same prices on Knoxville-Manchester flight deals on Cheapflights vs. FlightHub >95% of the time. Price accuracy is based on data collected from Knoxville-Manchester flight searches over the past month and is updated monthly.
- Most trusted provider: When it comes to deals on Knoxville-Manchester flights, Cheapflights users trust FlightHub the most. FlightHub has received a user feedback score of 3 out of 3 stars (3 being the best), meaning they have been trusted the most by Cheapflights users looking for Knoxville-Manchester flight deals. Provider user feedback score is based on Cheapflights searches over the past month and is updated monthly.
Best time to book a flight from Knoxville to Manchester
Have a flexible travel schedule? Discover the best time to fly to Manchester from Knoxville with our price prediction graph.
TYS-MAN
Estimated round-trip price
Rates are based on past data. Find the cheapest month and day to book your flight based on your travel requirements, then search for cheap deals.
Cheapflights Insights
Everything you need to know about your flight from Knoxville to Manchester
Reviews of airlines servicing Manchester
Get insights into the airlines that provide service to Manchester. Read reviews, discover amenities, and learn about the overall travel experience offered by airlines. Use this information to make informed decisions when choosing an airline for your flight to Manchester. Reviews last updated September 11, 2026.
See what other customers who have flown with Delta,Virgin Atlantic, andAmerican Airlines from Knoxville to Manchester have to say. You can also see how each airline compares in terms of entertainment options, comfort, food, crew/service, and boarding process.
Comfort
7.8
Boarding
8.1
Entertainment
7.8
Food
7.2
Crew
8.5
Overall
7.8
Reviews
1 / 20
4.0
OkayJennifer,Sep 2026
ORD - LGA
Comfort
7.8
Boarding
8.1
Entertainment
7.8
Food
7.2
Crew
8.5
Overall
7.8
Reviews
1 / 20
4.0
OkayJennifer,Sep 2026
ORD - LGA
Comfort
7.8
Boarding
8.1
Entertainment
7.8
Food
7.2
Crew
8.5
Overall
7.8
Reviews
1 / 20
4.0
OkayJennifer,Sep 2026
ORD - LGA
Comfort
7.8
Boarding
8.1
Entertainment
7.8
Food
7.2
Crew
8.5
Overall
7.8
Reviews
1 / 20
4.0
OkayJennifer,Sep 2026
ORD - LGA
Related info for your journey
Find useful and relevant information for your journey from Knoxville to Manchester. Access travel guides, tips, and recommendations to enhance your travel experience. Get information about local attractions, weather, transportation options, and more.
Traveling to a place near Manchester?
Book flights to Manchester if you plan to visit one of these locationsBolton
Rochdale
Huddersfield
Southport
Stockport
Salford
Bromborough
Llandudno
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Other flights to Manchester
Explore flights to Manchester departing from other origins. Flights are based on user searches made on Cheapflights and were last updated on September 11, 2026.
Knoxville and Manchester flights
Browse other Knoxville and Manchester flight options. Last updated on September 11, 2026.
Other flights from Knoxville
Browse through other flights departing from Knoxville. Flights are based on user searches made on Cheapflights and were last updated on September 11, 2026.
Popular flight searches
Check out other popular destinations found by fellow travelers in 2026
Top 3 airlines flying from Knoxville to Manchester
Discover the top 3 airlines that operate flights from Knoxville to Manchester. Compare their services, reliability, and customer satisfaction ratings to choose the airline that best suits your travel preferences and needs. Over the last 7 days, Cheapflights users made 7,457,451 searches. Data last updated September 11, 2026.
| Airline | Cheapest | Average | Flexibility | On-time |
|---|---|---|---|---|
| Cheapest$595 | Average$1,030 | FlexibilityNo cancel fee | On-timeN/A | |
| Cheapest$647 | Average$1,196 | FlexibilityNo cancel fee | On-time71% | |
| Cheapest$877 | Average$1,331 | FlexibilityNo cancel fee | On-time72% |