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$503+ Cheap flights from Des Moines (DSM) to Madrid, Spain (MAD)

This is the cheapest one-way flight price found by a Cheapflights user in the last 72 hours by searching for a flight departing on 10/30. Fares are subject to change and may not be available on all flights or dates of travel.
DSM — MAD
Oct 15 — Oct 221
Wed 10/15
Wed 10/22
1 adult, Economy
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Cheap flight deals from Des Moines to Madrid

Discover tips and strategies to find the most affordable flight options for your journey from Des Moines (DSM) to Madrid (MAD). Learn about various techniques such as flexible date searches, comparing prices across and setting up price alerts. Use these methods to find the cheapest flights available for your travel needs. Data last updated September 15, 2025.

Round-trip from

$596
(KLM)

One-way from

$503
(Iberia)

Popular in

June

Cheapest in

February

Average price

$915
From Des Moines to Madrid Barajas
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One-way flight from Des Moines to Madrid Barajas
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Highest demand for flights based on searches. 31% potential increase in price ($440 potential increase over avg. RT price).
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Cheapest flight prices on average. 6% potential price decrease ($58 potential savings vs. average RT price).
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Average for round-trip flights in September 2025
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Find flight deals from Des Moines to Madrid

Cheapest flights from Des Moines to Madrid
Explore the most affordable flight options available from Des Moines to Madrid. Find the lowest fares from popular airlines and budget airlines, with prices last updated on September 15, 2025.

This lastminute.com deal was found by Cheapflights users on 9/13. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure lastminute.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 10/282:13 pmDSM - MAD
1 stop11h 52mVirgin Atlantic
Tue 11/411:15 amMAD - DSM
2 stops16h 20mVirgin Atlantic
Deal found 9/13$588
This KLM deal was found by Cheapflights users on 9/15. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure KLM is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 10/54:14 pmDSM - MAD
1 stop34h 21mKLM
Tue 10/217:05 amMAD - DSM
2 stops16h 46mKLM
Deal found 9/15$596
This American Airlines deal was found by Cheapflights users on 9/15. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 10/56:00 amDSM - MAD
1 stop20h 35mAmerican Airlines
Tue 10/211:00 pmMAD - DSM
1 stop17h 08mAmerican Airlines
Deal found 9/15$599
This Finnair deal was found by Cheapflights users on 9/14. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Finnair is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 10/2911:15 amDSM - MAD
1 stop12h 30mMultiple Airlines
Wed 11/51:00 pmMAD - DSM
1 stop17h 30mMultiple Airlines
Deal found 9/14$603
This Trip.com deal was found by Cheapflights users on 9/14. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Trip.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 10/2910:50 amDSM - MAD
1 stop15h 15mVirgin Atlantic
Wed 11/511:15 amMAD - DSM
1 stop18h 15mVirgin Atlantic
Deal found 9/14$604
This Delta deal was found by Cheapflights users on 9/14. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 10/295:47 amDSM - MAD
2 stops19h 13mDelta
Wed 11/511:15 amMAD - DSM
1 stop18h 15mDelta
Deal found 9/14$607
This American Airlines deal was found by Cheapflights users on 9/15. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 10/309:30 amDSM - MAD
1 stop17h 55mAmerican Airlines
Thu 11/611:35 amMAD - DSM
1 stop19h 15mAmerican Airlines
Deal found 9/15$609

Cheapflights Fare Finder

 
Customize your flight search to find flights from Des Moines to Madrid that fit within your specific budget. Explore options based on user searches and filter the results based on your desired price range. Find flights that match your budget for a cost-effective journey. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated September 15, 2025.
Use the filters below to find and compare flights from Des Moines to Madrid that are best for you.

Fly from

Des Moines

Fly to

Madrid

Route

Depart

Return

Price

Des MoinesMadrid

DSM - MAD

DSMMAD

Des Moines

Sun 10/5

6:00 am-9:35 am

1 stop20h 35m

Madrid Barajas

Tue 10/21

1:00 pm-11:08 pm

1 stop17h 08m

$599

Des MoinesMadrid

DSM - MAD

DSMMAD

Des Moines

Wed 10/29

11:15 am-5:45 am

1 stop12h 30m

Madrid Barajas

Wed 11/5

1:00 pm-11:30 pm

1 stop17h 30m

$603

Des MoinesMadrid

DSM - MAD

DSMMAD

Des Moines

Wed 10/29

5:47 am-7:00 am

2 stops19h 13m

Madrid Barajas

Wed 11/5

11:15 am-9:20 am

2 stops29h 05m

$607

Des MoinesMadrid

DSM - MAD

DSMMAD

Des Moines

Thu 10/30

1:48 pm-8:50 am

2 stops13h 02m

Madrid Barajas

Thu 11/6

11:35 am-6:10 pm

1 stop13h 35m

$613

Des MoinesMadrid

DSM - MAD

DSMMAD

Des Moines

Thu 10/30

5:45 am-8:05 am

2 stops20h 20m

Madrid Barajas

Thu 11/6

11:15 am-11:44 pm

2 stops19h 29m

$642

Des MoinesMadrid

DSM - MAD

DSMMAD

Des Moines

Mon 10/13

11:31 am-8:05 am

2 stops13h 34m

Madrid Barajas

Mon 10/20

11:15 am-9:50 pm

2 stops17h 35m

$642

Des MoinesMadrid

DSM - MAD

DSMMAD

Des Moines

Wed 10/29

9:30 am-5:45 am

2 stops14h 15m

Madrid Barajas

Wed 11/5

1:15 pm-10:59 pm

2 stops16h 44m

$648

Des MoinesMadrid

DSM - MAD

DSMMAD

Des Moines

Thu 10/30

1:48 pm-7:55 am

1 stop12h 07m

$503

Des MoinesMadrid

DSM - MAD

DSMMAD

Des Moines

Thu 10/30

1:48 pm-8:50 am

2 stops13h 02m

$503

Des MoinesMadrid

DSM - MAD

DSMMAD

Des Moines

Thu 10/30

8:02 am-8:00 am

3 stops17h 58m

$520

Flights are sorted by cheapest round-trip flights first.

Deals found on 9/15

Best time to book a flight from Des Moines to Madrid

Have a flexible travel schedule? Discover the best time to fly to Madrid from Des Moines with our price prediction graph.
Estimated round-trip price
Rates are based on past data. Find the cheapest month and day to book your flight based on your travel requirements, then search for cheap deals.

Cheapflights Insights

Everything you need to know about your flight from Des Moines to Madrid

What is the cheapest month to book a flight from Des Moines to Madrid?

Currently, November is the cheapest month in which you can book a flight from Des Moines to Madrid (average of $543). Flying from Des Moines to Madrid in June is currently the most expensive (average of $1,054). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.

How much does it cost to fly round-trip from Des Moines to Madrid?

Reviews of airlines servicing Madrid

Get insights into the airlines that provide service to Madrid. Read reviews, discover amenities, and learn about the overall travel experience offered by airlines. Use this information to make informed decisions when choosing an airline for your flight to Madrid. Reviews last updated September 15, 2025.
Peruse reviews from past customers who have flown with Delta, United Airlines, and American Airlines from Des Moines to Madrid to help guide your decision. You can also see how each airline stacks up in terms of entertainment options, comfort, food, crew/service, and boarding process.
Delta
8.0
Very good
7,954 reviews

Crew

8.5

Comfort

7.9

Food

7.3

Entertainment

7.9

Overall

8.0

Boarding

8.2

Reviews

1 / 20
10.0
Excellent

Kim,May 2025

PIH - SLC

This trip was fine even with delay I had plenty of time to get connection flight!
Delta
8.0
Very good
7,954 reviews
Delta
8.0
Very good
7,954 reviews

Crew

8.5

Comfort

7.9

Food

7.3

Entertainment

7.9

Overall

8.0

Boarding

8.2

Reviews

1 / 20
10.0
Excellent

Kim,May 2025

PIH - SLC

This trip was fine even with delay I had plenty of time to get connection flight!
United Airlines
7.4
Good
8,929 reviews
Delta
8.0
Very good
7,954 reviews

Crew

8.5

Comfort

7.9

Food

7.3

Entertainment

7.9

Overall

8.0

Boarding

8.2

Reviews

1 / 20
10.0
Excellent

Kim,May 2025

PIH - SLC

This trip was fine even with delay I had plenty of time to get connection flight!
American Airlines
7.2
Good
10,000 reviews
Delta
8.0
Very good
7,954 reviews

Crew

8.5

Comfort

7.9

Food

7.3

Entertainment

7.9

Overall

8.0

Boarding

8.2

Reviews

1 / 20
10.0
Excellent

Kim,May 2025

PIH - SLC

This trip was fine even with delay I had plenty of time to get connection flight!
Iberia
7.0
Good
2,924 reviews
Delta
8.0
Very good
7,954 reviews

Crew

8.5

Comfort

7.9

Food

7.3

Entertainment

7.9

Overall

8.0

Boarding

8.2

Reviews

1 / 20
10.0
Excellent

Kim,May 2025

PIH - SLC

This trip was fine even with delay I had plenty of time to get connection flight!

Related info for your journey

Find useful and relevant information for your journey from Des Moines to Madrid. Access travel guides, tips, and recommendations to enhance your travel experience. Get information about local attractions, weather, transportation options, and more.

  • How long is the flight from Des Moines to Madrid?

    A quick flight from Des Moines to Madrid can take about 19h 13m. American Airlines provides one of the quickest options available for as low as $607. There are 4457 mi between Des Moines and Madrid. This flight may include one or multiple stops.

  • What are the cheapest airlines flying from Des Moines to Madrid round-trip?

    Our cheapest airline available from Des Moines to Madrid is United Airlines. Our recent data shows that you can find tickets from as low as $576 on this airline. Additional options worth looking into are American Airlines and Iberia, starting at $586 and $636 round-trip. These flights start at 40% lower than the current average price 3 months from now.

  • What are the cheapest airlines to fly from Des Moines to Madrid one-way?

    One-way options have recently been found by users for as low as $503 on Iberia. Other airlines that offer cheap prices include American Airlines from $503 and Air Canada from $520 one-way.

  • Can I find deals for flights from Des Moines to Madrid that include hotel bookings?

    Yes. In addition to deals on Des Moines to Madrid flights, Cheapflights offers vacation packages that include both flights and hotel.

  • How can I find direct flights from Des Moines to Madrid?

    After entering your origin and destination, apply the non-stop filter on the search result page to find direct flights from Des Moines to Madrid.

  • Can I find deals for business class flights from Des Moines to Madrid?

    Yes. Cheapflights offers flight deals from Des Moines to Madrid by cabin class. In addition to browsing deals, you can also filter by cabin class on the search results page after making a search.

  • What is the cheapest month to book a flight from Des Moines to Madrid?

    Currently, November is the cheapest month in which you can book a flight from Des Moines to Madrid (average of $543). Flying from Des Moines to Madrid in June is currently the most expensive (average of $1,054). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.

See more FAQs

Traveling to a place near Madrid?

Book flights to Madrid if you plan to visit one of these locations
Fuenlabrada
Getafe

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Alternative routes for Des Moines to Madrid

See prices for flight routes from nearby airports that may be better suited for you.
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Top 4 airlines flying from Des Moines to Madrid

Discover the top 4 airlines that operate flights from Des Moines to Madrid. Compare their services, reliability, and customer satisfaction ratings to choose the airline that best suits your travel preferences and needs. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated September 15, 2025.
AirlineCheapestAverageFlexibilityOn-time
United AirlinesCheapest$576Average$722FlexibilityNo cancel feeOn-time69%
American AirlinesCheapest$586Average$972FlexibilityNo cancel feeOn-time71%
IberiaCheapest$636Average$1,273FlexibilityNo cancel feeOn-time77%
DeltaCheapest$644Average$735FlexibilityNo cancel feeOn-timeN/A

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