HomeSearch by dateVacation packagesHotelsFlight dealsCar rentalTravel tips & news
Madrid

$321+ Cheap flights from Des Moines (DSM) to Madrid, Spain (MAD)

This is the cheapest one-way flight price found by a Cheapflights user in the last 72 hours by searching for a flight departing on 4/15. Fares are subject to change and may not be available on all flights or dates of travel.
DSM — MAD
Mar 20 — Mar 271
Fri 3/20
Fri 3/27
1 adult, Economy
We work with more than 300 partners to bring you better travel deals

Find cheap flights from Des Moines to Madrid with Cheapflights

1. Tell us where you want to go

Enter your travel information like dates, passengers, trip type (one-way or round trip), and preferred cabin class then click “Find deals”

2. Select your favorite providers

We find the providers serving your travel needs. Choose up to four travel providers to compare side-by-side for flights, hotels, or car rentals.

3. Compare prices and book

Review each provider’s pricing and select the best option for you! Book through your favorite provider’s website for a seamless experience.

Cheap flight deals from Des Moines to Madrid

Cheapest flights from Des Moines to Madrid
Explore the most affordable flight options available from Des Moines to Madrid. Find the lowest fares from popular airlines and budget airlines, with prices last updated on February 18, 2026.

This United Airlines deal was found by Cheapflights users on 2/15. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 4/138:04 am
DSM
-
MAD
2 stops17h 01m
United Airlines
Fri 4/2412:45 pm
MAD
-
DSM
2 stops28h 59m
United Airlines
Deal found 2/15$471
This United Airlines deal was found by Cheapflights users on 2/17. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 4/1211:25 am
DSM
-
MAD
2 stops13h 40m
United Airlines
Tue 4/2810:50 am
MAD
-
DSM
2 stops17h 37m
United Airlines
Deal found 2/17$482
This oojo deal was found by Cheapflights users on 2/14. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure oojo is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 4/218:03 pm
DSM
-
MAD
2 stops17h 02m
British Airways
Tue 4/2810:35 am
MAD
-
DSM
2 stops20h 14m
British Airways
Deal found 2/14$484
This United Airlines deal was found by Cheapflights users on 2/17. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 11/255:00 am
DSM
-
MAD
2 stops28h 40m
United Airlines
Fri 12/41:35 pm
MAD
-
DSM
2 stops34h 58m
United Airlines
Deal found 2/17$489
This American Airlines deal was found by Cheapflights users on 2/15. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 4/138:03 pm
DSM
-
MAD
1 stop10h 27m
American Airlines
Fri 4/243:55 pm
MAD
-
DSM
1 stop15h 04m
American Airlines
Deal found 2/15$491
This United Airlines deal was found by Cheapflights users on 2/15. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 4/128:04 am
DSM
-
MAD
2 stops17h 01m
United Airlines
Fri 4/248:25 am
MAD
-
DSM
2 stops21h 18m
United Airlines
Deal found 2/15$492
This Delta deal was found by Cheapflights users on 2/14. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 4/192:44 pm
DSM
-
MAD
1 stop14h 31m
Delta
Wed 4/296:00 am
MAD
-
DSM
2 stops18h 02m
Delta
Deal found 2/14$493
This United Airlines deal was found by Cheapflights users on 2/14. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 4/198:04 am
DSM
-
MAD
3 stops17h 56m
United Airlines
Tue 4/2811:15 am
MAD
-
DSM
2 stops17h 12m
United Airlines
Deal found 2/14$496
This Delta deal was found by Cheapflights users on 2/17. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 4/129:22 am
DSM
-
MAD
1 stop17h 33m
Delta
Fri 4/242:35 pm
MAD
-
DSM
1 stop27h 42m
Delta
Deal found 2/17$497
This Delta deal was found by Cheapflights users on 2/17. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 11/235:45 am
DSM
-
MAD
1 stop20h 30m
Delta
Fri 12/411:15 am
MAD
-
DSM
1 stop18h 14m
Delta
Deal found 2/17$500

Find flight deals from Des Moines to Madrid

Discover tips and strategies to find the most affordable flight options for your journey from Des Moines (DSM) to Madrid (MAD). Learn about various techniques such as flexible date searches, comparing prices across and setting up price alerts. Use these methods to find the cheapest flights available for your travel needs. Data last updated February 18, 2026.

Most accurate provider

FlightHub
3 stars

Most trusted provider

FlightHub
3 stars

Round-trip from

$471
(United Airlines)

One-way from

$321
(Trip.com)

Popular in

December

Cheapest in

January

Average price

$624
Provider with most accurate pricing for Des Moines-Madrid Barajas flight deals.
Search Deals
Provider most trusted by Cheapflights users for Des Moines-Madrid Barajas flights.
Search Deals
From Des Moines to Madrid Barajas
Search Deals
One-way flight from Des Moines to Madrid Barajas
Search Deals
Highest demand for flights based on searches. 1% potential increase in price ($16 potential increase over avg. RT price).
Search Deals
Cheapest flight prices on average. 8% potential price decrease ($75 potential savings vs. average RT price).
Search Deals
Average for round-trip flights in February 2026
Search Deals

Cheapflights Fare Finder

 
Customize your flight search to find flights from Des Moines to Madrid that fit within your specific budget. Explore options based on user searches and filter the results based on your desired price range. Find flights that match your budget for a cost-effective journey. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated February 18, 2026.
Use the filters below to find and compare flights from Des Moines to Madrid that are best for you.

Fly from

Des Moines

Fly to

Madrid

Route

Depart

Return

Price

Des MoinesMadrid

DSM - MAD

DSMMAD

Des Moines

Sun 4/12

12:00 pm-8:20 am

1 stop13h 20m

Madrid Barajas

Tue 4/28

12:20 pm-11:49 pm

2 stops18h 29m

$482

Des MoinesMadrid

DSM - MAD

DSMMAD

Des Moines

Sun 4/12

11:25 am-8:05 am

2 stops13h 40m

Madrid Barajas

Tue 4/28

10:50 am-9:27 pm

2 stops17h 37m

$482

Des MoinesMadrid

DSM - MAD

DSMMAD

Des Moines

Tue 4/14

8:04 am-8:05 am

2 stops17h 01m

Madrid Barajas

Fri 4/24

8:25 am-10:43 pm

2 stops21h 18m

$492

Des MoinesMadrid

DSM - MAD

DSMMAD

Des Moines

Sun 4/12

8:04 am-8:05 am

2 stops17h 01m

Madrid Barajas

Thu 4/23

6:05 am-8:34 pm

2 stops21h 29m

$492

Des MoinesMadrid

DSM - MAD

DSMMAD

Des Moines

Sun 4/19

11:51 am-12:15 pm

1 stop17h 24m

Madrid Barajas

Tue 4/28

6:00 am-8:39 pm

2 stops21h 39m

$493

Des MoinesMadrid

DSM - MAD

DSMMAD

Des Moines

Mon 4/20

2:44 pm-12:15 pm

1 stop14h 31m

Madrid Barajas

Tue 4/28

6:00 am-8:39 pm

2 stops21h 39m

$493

Des MoinesMadrid

DSM - MAD

DSMMAD

Des Moines

Sun 4/19

2:44 pm-12:15 pm

1 stop14h 31m

Madrid Barajas

Wed 4/29

6:00 am-5:02 pm

2 stops18h 02m

$493

Des MoinesMadrid

DSM - MAD

DSMMAD

Des Moines

Mon 4/13

7:28 am-9:55 am

1 stop19h 27m

Madrid Barajas

Wed 4/22

6:00 am-5:02 pm

2 stops18h 02m

$493

Des MoinesMadrid

DSM - MAD

DSMMAD

Des Moines

Mon 4/13

8:04 am-9:00 am

3 stops17h 56m

Madrid Barajas

Fri 4/24

11:15 am-9:27 pm

2 stops17h 12m

$496

Des MoinesMadrid

DSM - MAD

DSMMAD

Des Moines

Wed 4/15

6:00 am-10:00 am

2 stops21h 00m

$321

Flights are sorted by cheapest round-trip flights first.

Deals found on 2/14

Showing 1-10 of 14 results
1
2

Compare providers for flights from Des Moines to Madrid

Provider information is updated monthly. Please note that these providers often have deals for this flight, but the availability may vary on a day-by-day basis on Cheapflights.
Use the table below to compare price accuracy, trust ratings, and cancellation policies for each provider offering flight deals from Des Moines to Madrid in February.
ProviderPrice AccuracyTrust Score*
OvagoPrice Accuracy2 starsTrust Score*3 stars
AranGrantPrice Accuracy2 starsTrust Score*2 stars
FlightHubPrice Accuracy3 starsTrust Score*3 stars

*The Trust Score is based on feedback from users after their booking experience. It measures overall satisfaction, helping us identify issues like hidden fees, problems during the ticketing process, and the quality of customer service. This score is our best indicator of the provider's quality and reliability.

  • Most accurate provider: When it comes to deals on Des Moines-Madrid flights, users find the pricing of FlightHub to be most consistent on Cheapflights vs. FlightHub Users can find the same prices on Des Moines-Madrid flight deals on Cheapflights vs. FlightHub >95% of the time. Price accuracy is based on data collected from Des Moines-Madrid flight searches over the past month and is updated monthly.
  • Most trusted provider: When it comes to deals on Des Moines-Madrid flights, Cheapflights users trust FlightHub the most. FlightHub has received a user feedback score of 3 out of 3 stars (3 being the best), meaning they have been trusted the most by Cheapflights users looking for Des Moines-Madrid flight deals. Provider user feedback score is based on Cheapflights searches over the past month and is updated monthly.

Best time to book a flight from Des Moines to Madrid

Have a flexible travel schedule? Discover the best time to fly to Madrid from Des Moines with our price prediction graph.
Estimated round-trip price
Rates are based on past data. Find the cheapest month and day to book your flight based on your travel requirements, then search for cheap deals.

Cheapflights Insights

Everything you need to know about your flight from Des Moines to Madrid

What is the cheapest month to book a flight from Des Moines to Madrid?

Currently, April is the cheapest month in which you can book a flight from Des Moines to Madrid (average of $449). Flying from Des Moines to Madrid in June is currently the most expensive (average of $1,183). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.

Reviews of airlines servicing Madrid

Get insights into the airlines that provide service to Madrid. Read reviews, discover amenities, and learn about the overall travel experience offered by airlines. Use this information to make informed decisions when choosing an airline for your flight to Madrid. Reviews last updated February 18, 2026.
Peruse reviews from past customers who have flown with Delta, American Airlines, and Iberia from Des Moines to Madrid to help guide your decision. You can also see how each airline stacks up in terms of entertainment options, comfort, food, crew/service, and boarding process.
Delta
7.9
Good
8,207 reviews

Crew

8.5

Entertainment

7.8

Comfort

7.9

Food

7.2

Overall

7.9

Boarding

8.1

Reviews

1 / 20
6.0
Good

Jim,Nov 2025

AVL - ATL

The exit row seats without a seat in front are great for leg room but don’t have a fold out entertainment console so you’re forced to use the screen several feet in front of you (there is, at least, a remote). Best to bring a tablet loaded with entertainment or a book.
Delta
7.9
Good
8,207 reviews
Delta
7.9
Good
8,207 reviews

Crew

8.5

Entertainment

7.8

Comfort

7.9

Food

7.2

Overall

7.9

Boarding

8.1

Reviews

1 / 20
6.0
Good

Jim,Nov 2025

AVL - ATL

The exit row seats without a seat in front are great for leg room but don’t have a fold out entertainment console so you’re forced to use the screen several feet in front of you (there is, at least, a remote). Best to bring a tablet loaded with entertainment or a book.
American Airlines
7.2
Good
11,305 reviews
Delta
7.9
Good
8,207 reviews

Crew

8.5

Entertainment

7.8

Comfort

7.9

Food

7.2

Overall

7.9

Boarding

8.1

Reviews

1 / 20
6.0
Good

Jim,Nov 2025

AVL - ATL

The exit row seats without a seat in front are great for leg room but don’t have a fold out entertainment console so you’re forced to use the screen several feet in front of you (there is, at least, a remote). Best to bring a tablet loaded with entertainment or a book.
Iberia
7.0
Good
3,117 reviews
Delta
7.9
Good
8,207 reviews

Crew

8.5

Entertainment

7.8

Comfort

7.9

Food

7.2

Overall

7.9

Boarding

8.1

Reviews

1 / 20
6.0
Good

Jim,Nov 2025

AVL - ATL

The exit row seats without a seat in front are great for leg room but don’t have a fold out entertainment console so you’re forced to use the screen several feet in front of you (there is, at least, a remote). Best to bring a tablet loaded with entertainment or a book.

Related info for your journey

Find useful and relevant information for your journey from Des Moines to Madrid. Access travel guides, tips, and recommendations to enhance your travel experience. Get information about local attractions, weather, transportation options, and more.

  • How long is the flight from Des Moines to Madrid?

    A quick flight from Des Moines to Madrid can take about 13h 40m. United Airlines provides one of the quickest options available for as low as $482. There are 4457 mi between Des Moines and Madrid.

  • What are the cheapest airlines flying from Des Moines to Madrid round-trip?

    Our cheapest airline available from Des Moines to Madrid is Delta. Our recent data shows that you can find tickets from as low as $488 on this airline. Additional options worth looking into are American Airlines and Iberia, starting at $513 and $636 round-trip. These flights start at 48% lower than the current average price 3 months from now.

  • Can I find deals for flights from Des Moines to Madrid that include hotel bookings?

    Yes. In addition to deals on Des Moines to Madrid flights, Cheapflights offers vacation packages that include both flights and hotel.

  • How can I find direct flights from Des Moines to Madrid?

    After entering your origin and destination, apply the non-stop filter on the search result page to find direct flights from Des Moines to Madrid.

  • Can I find deals for business class flights from Des Moines to Madrid?

    Yes. Cheapflights offers flight deals from Des Moines to Madrid by cabin class. In addition to browsing deals, you can also filter by cabin class on the search results page after making a search.

  • What is the cheapest month to book a flight from Des Moines to Madrid?

    Currently, April is the cheapest month in which you can book a flight from Des Moines to Madrid (average of $449). Flying from Des Moines to Madrid in June is currently the most expensive (average of $1,183). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.

See more FAQs

Traveling to a place near Madrid?

Book flights to Madrid if you plan to visit one of these locations
Getafe

Browse thousands of different options on Cheapflights for your next trip

Toggle through the tabs below to find thousands of options on Cheapflights for your next trip.

Alternative routes for Des Moines to Madrid

See prices for flight routes from nearby airports that may be better suited for you.
Cedar Rapids to Madrid flights
Omaha to Madrid flights
Waterloo to Madrid flights

Top 3 airlines flying from Des Moines to Madrid

Discover the top 3 airlines that operate flights from Des Moines to Madrid. Compare their services, reliability, and customer satisfaction ratings to choose the airline that best suits your travel preferences and needs. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated February 18, 2026.
AirlineCheapestAverageFlexibilityOn-time
DeltaCheapest$488Average$1,880FlexibilityNo cancel feeOn-timeN/A
American AirlinesCheapest$513Average$1,025FlexibilityNo cancel feeOn-time71%
IberiaCheapest$636Average$1,361FlexibilityNo cancel feeOn-time77%

100% Free

Cheapflights is completely free to use, so you can start saving the moment you arrive.

Book with Flexibility

Our users can plan ahead with confidence and find flights with no change fees

Travel Smart

Millions of people come to us for their flight needs every year. We help make travel planning easy by providing useful insights and data-driven graphs that can inform your decisions.
Site
©2026 Cheapflights