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$319+ Cheap flights from Des Moines (DSM) to Madrid, Spain (MAD)

This is the cheapest one-way flight price found by a Cheapflights user in the last 72 hours by searching for a flight departing on 10/31. Fares are subject to change and may not be available on all flights or dates of travel.
DSM — MAD
nov 15 — nov 221
sáb 11/15
sáb 11/22
1 adult, Economy
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Find flight deals from Des Moines to Madrid

Cheapest flights from Des Moines to Madrid
Explore the most affordable flight options available from Des Moines to Madrid. Find the lowest fares from popular airlines and budget airlines, with prices last updated on outubro 16, 2025.

This Flighttix deal was found by Cheapflights users on 10/14. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Flighttix is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
seg 10/2710:50 amDSM - MAD
1 stop15h 15mVirgin Atlantic
qua 11/1211:15 amMAD - DSM
1 stop18h 18mVirgin Atlantic
Deal found 10/14$425
This lastminute.com deal was found by Cheapflights users on 10/14. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure lastminute.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
sex 11/2811:28 amDSM - MAD
1 stop13h 32mVirgin Atlantic
sex 12/511:15 amMAD - DSM
2 stops41h 00mVirgin Atlantic
Deal found 10/14$454
This Ticket deal was found by Cheapflights users on 10/16. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Ticket is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
dom 11/305:35 amDSM - MAD
1 stop20h 40mKLM
dom 12/76:00 amMAD - DSM
2 stops18h 03mKLM
Deal found 10/16$460
This Delta deal was found by Cheapflights users on 10/14. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
dom 11/95:35 amDSM - MAD
1 stop20h 40mDelta
ter 11/186:00 amMAD - DSM
2 stops23h 33mDelta
Deal found 10/14$462
This Delta deal was found by Cheapflights users on 10/14. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
sáb 11/85:15 pmDSM - MAD
1 stop33h 00mDelta
ter 11/186:00 amMAD - DSM
2 stops23h 33mDelta
Deal found 10/14$467
This United Airlines deal was found by Cheapflights users on 10/13. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
seg 11/1011:26 amDSM - MAD
2 stops22h 14mUnited Airlines
ter 11/181:35 pmMAD - DSM
2 stops38h 57mUnited Airlines
Deal found 10/13$474
This Flighttix deal was found by Cheapflights users on 10/14. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Flighttix is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
sex 11/288:02 amDSM - MAD
2 stops16h 58mMultiple Airlines
sex 12/51:45 pmMAD - DSM
2 stops34h 39mMultiple Airlines
Deal found 10/14$479
This Delta deal was found by Cheapflights users on 10/14. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
ter 11/112:17 pmDSM - MAD
2 stops21h 53mDelta
ter 11/186:00 amMAD - DSM
2 stops23h 33mDelta
Deal found 10/14$480

Cheap flight deals from Des Moines to Madrid

Discover tips and strategies to find the most affordable flight options for your journey from Des Moines (DSM) to Madrid (MAD). Learn about various techniques such as flexible date searches, comparing prices across and setting up price alerts. Use these methods to find the cheapest flights available for your travel needs. Data last updated outubro 16, 2025.

Most accurate provider

FlightHub
3 stars

Most trusted provider

FlightHub
3 stars

Round-trip from

$425
(Flighttix)

One-way from

$319
(Mytrip)

Popular in

June

Cheapest in

January

Average price

$844
Provider with most accurate pricing for Des Moines-Madrid Barajas flight deals.
Search Deals
Provider most trusted by Cheapflights users for Des Moines-Madrid Barajas flights.
Search Deals
From Des Moines to Madrid Barajas
Search Deals
One-way flight from Des Moines to Madrid Barajas
Search Deals
Highest demand for flights based on searches. 30% potential increase in price ($436 potential increase over avg. RT price).
Search Deals
Cheapest flight prices on average. 6% potential price decrease ($57 potential savings vs. average RT price).
Search Deals
Average for round-trip flights in October 2025
Search Deals

Cheapflights Fare Finder

 
Customize your flight search to find flights from Des Moines to Madrid that fit within your specific budget. Explore options based on user searches and filter the results based on your desired price range. Find flights that match your budget for a cost-effective journey. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated outubro 16, 2025.
Use the filters below to find and compare flights from Des Moines to Madrid that are best for you.

Fly from

Des Moines

Fly to

Madrid

Route

Depart

Return

Price

Des MoinesMadrid

DSM - MAD

DSMMAD

Des Moines

seg 10/27

10:00 am-8:05 am

2 stops16h 05m

Madrid Barajas

qua 11/12

10:00 am-8:47 pm

2 stops17h 47m

$443

Des MoinesMadrid

DSM - MAD

DSMMAD

Des Moines

dom 11/9

6:17 am-9:15 am

2 stops19h 58m

Madrid Barajas

ter 11/18

6:00 am-10:33 pm

2 stops23h 33m

$466

Des MoinesMadrid

DSM - MAD

DSMMAD

Des Moines

seg 11/10

11:26 am-4:40 pm

2 stops22h 14m

Madrid Barajas

ter 11/18

1:35 pm-9:32 pm

2 stops38h 57m

$474

Des MoinesMadrid

DSM - MAD

DSMMAD

Des Moines

ter 11/11

1:05 pm-4:40 pm

2 stops20h 35m

Madrid Barajas

ter 11/18

1:35 pm-9:32 pm

2 stops38h 57m

$474

Des MoinesMadrid

DSM - MAD

DSMMAD

Des Moines

qua 11/12

1:05 pm-4:40 pm

2 stops20h 35m

Madrid Barajas

ter 11/18

1:35 pm-9:32 pm

2 stops38h 57m

$474

Des MoinesMadrid

DSM - MAD

DSMMAD

Des Moines

qua 11/12

10:21 am-5:40 pm

2 stops24h 19m

Madrid Barajas

ter 11/18

6:00 am-10:33 pm

2 stops23h 33m

$481

Des MoinesMadrid

DSM - MAD

DSMMAD

Des Moines

sex 11/28

5:40 am-8:00 am

1 stop19h 20m

Madrid Barajas

sex 12/5

10:00 am-9:40 am

2 stops30h 40m

$493

Des MoinesMadrid

DSM - MAD

DSMMAD

Des Moines

qui 11/6

5:47 am-9:15 am

1 stop20h 28m

Madrid Barajas

qua 11/12

10:00 am-8:47 pm

2 stops17h 47m

$493

Des MoinesMadrid

DSM - MAD

DSMMAD

Des Moines

sex 10/31

8:00 am-2:05 pm

2 stops24h 05m

$319

Des MoinesMadrid

DSM - MAD

DSMMAD

Des Moines

sáb 11/15

3:15 pm-8:00 am

2 stops33h 45m

$397

Flights are sorted by cheapest round-trip flights first.

Deals found on 10/13

Showing 1-10 of 13 results
1
2

Compare providers for flights from Des Moines to Madrid

Provider information is updated monthly. Please note that these providers often have deals for this flight, but the availability may vary on a day-by-day basis on Cheapflights.
Use the table below to compare price accuracy, trust ratings, and cancellation policies for each provider offering flight deals from Des Moines to Madrid in October.
ProviderPrice AccuracyTrust Score*
FlightHubPrice Accuracy3 starsTrust Score*3 stars
eDreamsPrice Accuracy3 starsTrust Score*3 stars
AranGrantPrice Accuracy3 starsTrust Score*3 stars
OvagoPrice Accuracy2 starsTrust Score*2 stars

*The Trust Score is based on feedback from users after their booking experience. It measures overall satisfaction, helping us identify issues like hidden fees, problems during the ticketing process, and the quality of customer service. This score is our best indicator of the provider's quality and reliability.

  • Most accurate provider: When it comes to deals on Des Moines-Madrid flights, users find the pricing of FlightHub to be most consistent on Cheapflights vs. FlightHub Users can find the same prices on Des Moines-Madrid flight deals on Cheapflights vs. FlightHub >95% of the time. Price accuracy is based on data collected from Des Moines-Madrid flight searches over the past month and is updated monthly.
  • Most trusted provider: When it comes to deals on Des Moines-Madrid flights, Cheapflights users trust FlightHub the most. FlightHub has received a user feedback score of 3 out of 3 stars (3 being the best), meaning they have been trusted the most by Cheapflights users looking for Des Moines-Madrid flight deals. Provider user feedback score is based on Cheapflights searches over the past month and is updated monthly.

Best time to book a flight from Des Moines to Madrid

Have a flexible travel schedule? Discover the best time to fly to Madrid from Des Moines with our price prediction graph.
Estimated round-trip price
Rates are based on past data. Find the cheapest month and day to book your flight based on your travel requirements, then search for cheap deals.

Cheapflights Insights

Everything you need to know about your flight from Des Moines to Madrid

What is the cheapest month to book a flight from Des Moines to Madrid?

Currently, November is the cheapest month in which you can book a flight from Des Moines to Madrid (average of $575). Flying from Des Moines to Madrid in June is currently the most expensive (average of $1,240). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.

Reviews of airlines servicing Madrid

Get insights into the airlines that provide service to Madrid. Read reviews, discover amenities, and learn about the overall travel experience offered by airlines. Use this information to make informed decisions when choosing an airline for your flight to Madrid. Reviews last updated outubro 16, 2025.
Peruse reviews from past customers who have flown with Delta, American Airlines, and Iberia from Des Moines to Madrid to help guide your decision. You can also see how each airline stacks up in terms of entertainment options, comfort, food, crew/service, and boarding process.
Delta
7.9
Good
7,977 reviews

Food

7.3

Boarding

8.2

Entertainment

7.9

Overall

7.9

Comfort

7.9

Crew

8.5

Reviews

1 / 20
8.0
Excellent

Matthew,Oct 2025

GSP - ATL

This is always a full flight since it is the connecting route to primary destinations through Atlanta. That said, the crew handles the full load well. Not much more to say, it is a short flight with no in-flight services due to the length.
Delta
7.9
Good
7,977 reviews
Delta
7.9
Good
7,977 reviews

Food

7.3

Boarding

8.2

Entertainment

7.9

Overall

7.9

Comfort

7.9

Crew

8.5

Reviews

1 / 20
8.0
Excellent

Matthew,Oct 2025

GSP - ATL

This is always a full flight since it is the connecting route to primary destinations through Atlanta. That said, the crew handles the full load well. Not much more to say, it is a short flight with no in-flight services due to the length.
American Airlines
7.2
Good
11,040 reviews
Delta
7.9
Good
7,977 reviews

Food

7.3

Boarding

8.2

Entertainment

7.9

Overall

7.9

Comfort

7.9

Crew

8.5

Reviews

1 / 20
8.0
Excellent

Matthew,Oct 2025

GSP - ATL

This is always a full flight since it is the connecting route to primary destinations through Atlanta. That said, the crew handles the full load well. Not much more to say, it is a short flight with no in-flight services due to the length.
Iberia
7.0
Good
2,994 reviews
Delta
7.9
Good
7,977 reviews

Food

7.3

Boarding

8.2

Entertainment

7.9

Overall

7.9

Comfort

7.9

Crew

8.5

Reviews

1 / 20
8.0
Excellent

Matthew,Oct 2025

GSP - ATL

This is always a full flight since it is the connecting route to primary destinations through Atlanta. That said, the crew handles the full load well. Not much more to say, it is a short flight with no in-flight services due to the length.

Related info for your journey

Find useful and relevant information for your journey from Des Moines to Madrid. Access travel guides, tips, and recommendations to enhance your travel experience. Get information about local attractions, weather, transportation options, and more.

  • How long is the flight from Des Moines to Madrid?

    A quick flight from Des Moines to Madrid can take about 16h 05m. Virgin Atlantic provides one of the quickest options available for as low as $443. There are 4457 mi between Des Moines and Madrid. This flight may include one or multiple stops.

  • What are the cheapest airlines flying from Des Moines to Madrid round-trip?

    Our cheapest airline available from Des Moines to Madrid is American Airlines. Our recent data shows that you can find tickets from as low as $584 on this airline. Additional options worth looking into are Delta and Iberia, starting at $644 and $686 round-trip. These flights start at 40% lower than the current average price 3 months from now.

  • What are the cheapest airlines to fly from Des Moines to Madrid one-way?

    One-way options have recently been found by users for as low as $397 on Air Canada. Other airlines that offer cheap prices include Iberia from $441 and American Airlines from $469 one-way.

  • Can I find deals for flights from Des Moines to Madrid that include hotel bookings?

    Yes. In addition to deals on Des Moines to Madrid flights, Cheapflights offers vacation packages that include both flights and hotel.

  • How can I find direct flights from Des Moines to Madrid?

    After entering your origin and destination, apply the non-stop filter on the search result page to find direct flights from Des Moines to Madrid.

  • Can I find deals for business class flights from Des Moines to Madrid?

    Yes. Cheapflights offers flight deals from Des Moines to Madrid by cabin class. In addition to browsing deals, you can also filter by cabin class on the search results page after making a search.

  • What is the cheapest month to book a flight from Des Moines to Madrid?

    Currently, November is the cheapest month in which you can book a flight from Des Moines to Madrid (average of $575). Flying from Des Moines to Madrid in June is currently the most expensive (average of $1,240). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.

See more FAQs

Traveling to a place near Madrid?

Book flights to Madrid if you plan to visit one of these locations
Fuenlabrada
Getafe

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Alternative routes for Des Moines to Madrid

See prices for flight routes from nearby airports that may be better suited for you.
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Top 3 airlines flying from Des Moines to Madrid

Discover the top 3 airlines that operate flights from Des Moines to Madrid. Compare their services, reliability, and customer satisfaction ratings to choose the airline that best suits your travel preferences and needs. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated outubro 16, 2025.
AirlineCheapestAverageFlexibilityOn-time
American AirlinesCheapest$584Average$1,006FlexibilityNo cancel feeOn-time71%
DeltaCheapest$644Average$735FlexibilityNo cancel feeOn-timeN/A
IberiaCheapest$686Average$1,340FlexibilityNo cancel feeOn-time77%

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