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Lyon

$525+ Cheap flights from South Carolina to Lyon (LYS)

This is the cheapest round-trip flight price found by a Cheapflights user in the last 72 hours by searching for a flight departing on 1/30. Fares are subject to change and may not be available on all flights or dates of travel.
CHS — LYS
Jan 17 — Jan 241
Sat 1/17
Sat 1/24
1 adult, Economy
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Cheap flight deals from South Carolina to Lyon

Cheapest flights from South Carolina to Lyon
Explore the most affordable flight options available from South Carolina to Lyon. Find the lowest fares from popular airlines and budget airlines, with prices last updated on December 18, 2025.

This Gotogate deal was found by Cheapflights users on 12/17. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Gotogate is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 12/312:50 pmGSP - LYS
2 stops14h 15mMultiple Airlines
Sun 1/46:10 amLYS - GSP
2 stops20h 37mMultiple Airlines
Deal found 12/17$1,656
This Ovago deal was found by Cheapflights users on 12/16. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Ovago is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 12/256:25 pmCLT - LYS
1 stop12h 00mMultiple Airlines
Sun 1/411:20 pmLYS - CLT
2 stops22h 40mMultiple Airlines
Deal found 12/16$1,919
This Ovago deal was found by Cheapflights users on 12/16. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Ovago is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 12/252:52 pmCLT - LYS
2 stops15h 03mIberia
Sun 1/411:20 pmLYS - CLT
2 stops22h 40mIberia
Deal found 12/16$1,939
This Mytrip deal was found by Cheapflights users on 12/16. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Mytrip is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 12/166:50 pmCLT - LYS
2 stops20h 35mMultiple Airlines
Sat 12/203:40 pmLYS - CLT
3 stops31h 15mMultiple Airlines
Deal found 12/16$2,112
This KAYAK deal was found by Cheapflights users on 12/15. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure KAYAK is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 12/1711:00 pmCLT - LYS
1 stop13h 05mMultiple Airlines
Sun 1/411:20 pmLYS - CLT
2 stops25h 40mMultiple Airlines
Deal found 12/15$2,154
This United Airlines deal was found by Cheapflights users on 12/14. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 12/1710:43 amCLT - LYS
2 stops18h 27mUnited Airlines
Sun 1/46:10 amLYS - CLT
2 stops21h 10mUnited Airlines
Deal found 12/14$2,379
This American Airlines deal was found by Cheapflights users on 12/15. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 12/1711:00 pmCLT - LYS
1 stop13h 05mAmerican Airlines
Sun 1/410:30 amLYS - CLT
1 stop33h 40mAmerican Airlines
Deal found 12/15$2,506
This Lufthansa deal was found by Cheapflights users on 12/16. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Lufthansa is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 12/166:50 pmCLT - LYS
1 stop16h 50mLufthansa
Sat 12/206:25 pmLYS - CLT
1 stop28h 30mLufthansa
Deal found 12/16$2,560
This Air Canada deal was found by Cheapflights users on 12/17. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Air Canada is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 12/318:34 amGSP - LYS
3 stops20h 31mAir Canada
Sun 1/41:55 pmLYS - GSP
3 stops27h 01mAir Canada
Deal found 12/17$6,483

Find flight deals from South Carolina to Lyon

Keep the following information in mind while searching for South Carolina to Lyon flight deals. Data was last updated December 18, 2025.

Round-trip from

$525
(Air Canada)
From South Carolina to Lyon-Saint Exupéry
Search Deals

Cheapflights Fare Finder

 
Customize your flight search to find flights from South Carolina to Lyon that fit within your specific budget. Explore options based on user searches and filter the results based on your desired price range. Find flights that match your budget for a cost-effective journey. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated December 18, 2025.
Use the filters below to find and compare flights from South Carolina to Lyon that are best for you.

Fly from

South Carolina

Fly to

Lyon

Route

Depart

Return

Price

GreenvilleLyon

GSP - LYS

GSPLYS

Greenville

Fri 1/30

6:20 am-11:05 am

2 stops22h 45m

Lyon-Saint Exupéry

Tue 2/3

1:40 pm-11:48 pm

2 stops40h 08m

$525

CharlotteLyon

CLT - LYS

CLTLYS

Charlotte Douglas

Thu 1/22

4:37 pm-8:20 pm

2 stops21h 43m

Lyon-Saint Exupéry

Wed 1/28

7:00 pm-6:26 pm

2 stops29h 26m

$690

CharlotteLyon

CLT - LYS

CLTLYS

Charlotte Douglas

Sun 1/11

11:38 am-10:05 am

2 stops16h 27m

Lyon-Saint Exupéry

Sun 1/18

8:10 pm-11:08 pm

2 stops32h 58m

$721

CharlotteLyon

CLT - LYS

CLTLYS

Charlotte Douglas

Thu 1/22

11:12 am-10:30 pm

2 stops29h 18m

Lyon-Saint Exupéry

Wed 1/28

7:55 pm-11:59 pm

3 stops34h 04m

$754

CharlotteLyon

CLT - LYS

CLTLYS

Charlotte Douglas

Sun 1/11

5:35 pm-11:05 am

2 stops35h 30m

Lyon-Saint Exupéry

Sun 1/18

1:05 pm-4:55 pm

1 stop33h 50m

$811

CharlotteLyon

CLT - LYS

CLTLYS

Charlotte Douglas

Wed 1/7

7:01 am-11:05 am

2 stops22h 04m

Lyon-Saint Exupéry

Thu 5/7

1:55 pm-12:33 pm

2 stops28h 38m

$868

CharlotteLyon

CLT - LYS

CLTLYS

Charlotte Douglas

Wed 1/7

7:50 am-11:05 am

2 stops21h 15m

Lyon-Saint Exupéry

Thu 5/7

1:55 pm-5:23 pm

2 stops33h 28m

$872

CharlotteLyon

CLT - LYS

CLTLYS

Charlotte Douglas

Wed 1/7

7:50 am-11:05 am

2 stops21h 15m

Lyon-Saint Exupéry

Thu 5/7

9:25 am-4:45 pm

1 stop13h 20m

$885

GreenvilleLyon

GSP - LYS

GSPLYS

Greenville

Wed 12/31

2:50 pm-11:05 am

2 stops14h 15m

Lyon-Saint Exupéry

Sun 1/4

6:10 am-8:47 pm

2 stops20h 37m

$1,656

GreenvilleLyon

GSP - LYS

GSPLYS

Greenville

Wed 12/31

8:34 am-11:05 am

3 stops20h 31m

Lyon-Saint Exupéry

Sun 1/4

1:55 pm-10:56 am

3 stops27h 01m

$6,483

Flights are sorted by cheapest round-trip flights first.

Deals found on 12/15

Best time to book a flight from South Carolina to Lyon

Have a flexible travel schedule? Discover the best time to fly to Lyon from South Carolina with our price prediction graph.
Estimated round-trip price
Rates are based on past data. Find the cheapest month and day to book your flight based on your travel requirements, then search for cheap deals.

Cheapflights Insights

Everything you need to know about your flight from South Carolina to Lyon

What is the cheapest time of day to fly from SC to LYS?

Find hourly flight availability from South Carolina to Lyon. Discover flight options and departure times throughout the day, allowing you to choose a departure time that suits your schedule. Data last updated December 18, 2025.

A simple way to save on the total cost of your ticket is to fly from South Carolina to Lyon in the morning. If you’re flexible enough to do this you can expect to save up to 22% on your trip compared to booking a flight at noon.

Related info for your journey

Find useful and relevant information for your journey from South Carolina to Lyon. Access travel guides, tips, and recommendations to enhance your travel experience. Get information about local attractions, weather, transportation options, and more.

  • What airport do you fly into for flights to Lyon from South Carolina?

    For a flight from South Carolina to Lyon, you will be flying into Lyon-Saint Exupéry. Lyon-Saint Exupéry (LYS) is just 12.5 mi from the center of the city.

  • How long is the flight from South Carolina to Lyon?

    Air Canada, British Airways, and Scandinavian Airlines can get you from South Carolina to Lyon in just under 16h 27m. Your travel time can differ by up to 6h 18m. The distance between South Carolina and Lyon is about 4357 mi. This flight may include one or multiple stops.

  • Can I find deals for flights from South Carolina to Lyon that include hotel bookings?

    Yes. In addition to deals on South Carolina to Lyon flights, Cheapflights offers vacation packages that include both flights and hotel.

  • How can I find direct flights from South Carolina to Lyon?

    After entering your origin and destination, apply the non-stop filter on the search result page to find direct flights from South Carolina to Lyon.

  • Can I find deals for business class flights from South Carolina to Lyon?

    Yes. Cheapflights offers flight deals from South Carolina to Lyon by cabin class. In addition to browsing deals, you can also filter by cabin class on the search results page after making a search.

See more FAQs

Traveling to a place near Lyon?

Book flights to Lyon if you plan to visit one of these locations
Annemasse
Huez

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Top airline flying from South Carolina to Lyon

Discover the top airline that operate flights from South Carolina to Lyon. Compare their services, reliability, and customer satisfaction ratings to choose the airline that best suits your travel preferences and needs. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated December 18, 2025.
AirlineCheapestAverageFlexibilityOn-time
United AirlinesCheapest$826Average$1,126FlexibilityNo cancel feeOn-time69%

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