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Lyon

$240+ Cheap flights from South Carolina to Lyon (LYS)

This is the cheapest one-way flight price found by a Cheapflights user in the last 72 hours by searching for a flight departing on 10/16. Fares are subject to change and may not be available on all flights or dates of travel.
CHS — LYS
Oct 15 — Oct 221
Wed 10/15
Wed 10/22
1 adult, Economy
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Cheap flight deals from South Carolina to Lyon

Keep the following information in mind while searching for South Carolina to Lyon flight deals. Data was last updated September 15, 2025.

Round-trip from

$556
(FlightHub)

One-way from

$240
(Kiwi.com)
From South Carolina to Lyon-Saint Exupéry
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One-way flight from South Carolina to Lyon-Saint Exupéry
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Find flight deals from South Carolina to Lyon

Cheapest flights from South Carolina to Lyon
Explore the most affordable flight options available from South Carolina to Lyon. Find the lowest fares from popular airlines and budget airlines, with prices last updated on September 15, 2025.

This Mytrip deal was found by Cheapflights users on 9/14. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Mytrip is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 10/296:00 amCLT - LYS
3 stops24h 10mMultiple Airlines
Wed 11/57:00 amLYS - CLT
3 stops17h 47mMultiple Airlines
Deal found 9/14$565
This Gotogate deal was found by Cheapflights users on 9/15. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Gotogate is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 10/193:15 pmCLT - LYS
2 stops37h 20mAir Canada
Tue 11/410:45 amLYS - CLT
2 stops16h 12mAir Canada
Deal found 9/15$572
This Flightnetwork deal was found by Cheapflights users on 9/15. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Flightnetwork is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 10/193:15 pmCLT - LYS
2 stops37h 20mMultiple Airlines
Tue 11/48:55 amLYS - CLT
1 stop14h 00mMultiple Airlines
Deal found 9/15$584
This Expedia deal was found by Cheapflights users on 9/14. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Expedia is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 10/295:36 pmGSP - LYS
2 stops20h 49mScandinavian Airlines
Wed 11/58:10 pmLYS - GSP
2 stops33h 45mScandinavian Airlines
Deal found 9/14$590
This Kiwi.com deal was found by Cheapflights users on 9/15. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 10/196:40 pmCLT - LYS
1 stop11h 40mLufthansa
Tue 11/48:55 amLYS - CLT
1 stop14h 00mLufthansa
Deal found 9/15$591
This FlightHub deal was found by Cheapflights users on 9/14. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure FlightHub is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 12/410:00 amCLT - LYS
2 stops27h 25mScandinavian Airlines
Mon 12/810:50 amLYS - CLT
2 stops41h 56mScandinavian Airlines
Deal found 9/14$616
This Air Canada deal was found by Cheapflights users on 9/13. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Air Canada is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 11/266:40 amCLT - LYS
2 stops22h 25mAir Canada
Tue 1/610:45 amLYS - CLT
2 stops40h 12mAir Canada
Deal found 9/13$651
This Expedia deal was found by Cheapflights users on 9/15. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Expedia is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 10/193:45 pmCLT - LYS
1 stop26h 00mIberia
Tue 11/412:25 pmLYS - CLT
2 stops31h 06mIberia
Deal found 9/15$658
This Booking.com deal was found by Cheapflights users on 9/12. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Booking.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 12/42:52 pmGSP - LYS
2 stops38h 13mMultiple Airlines
Mon 12/83:05 pmLYS - GSP
2 stops38h 54mMultiple Airlines
Deal found 9/12$680
This United Airlines deal was found by Cheapflights users on 9/15. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 10/157:00 amGSP - LYS
2 stops27h 40mUnited Airlines
Wed 10/226:50 amLYS - GSP
2 stops21h 49mUnited Airlines
Deal found 9/15$687

Cheapflights Fare Finder

 
Customize your flight search to find flights from South Carolina to Lyon that fit within your specific budget. Explore options based on user searches and filter the results based on your desired price range. Find flights that match your budget for a cost-effective journey. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated September 15, 2025.
Use the filters below to find and compare flights from South Carolina to Lyon that are best for you.

Fly from

South Carolina

Fly to

Lyon

Route

Depart

Return

Price

CharlotteLyon

CLT - LYS

CLTLYS

Charlotte Douglas

Sun 10/19

3:15 pm-10:35 am

2 stops37h 20m

Lyon-Saint Exupéry

Tue 11/4

10:45 am-8:57 pm

2 stops16h 12m

$572

CharlotteLyon

CLT - LYS

CLTLYS

Charlotte Douglas

Sun 10/19

3:15 pm-10:35 am

2 stops37h 20m

Lyon-Saint Exupéry

Tue 11/4

8:55 am-4:55 pm

1 stop14h 00m

$584

CharlotteLyon

CLT - LYS

CLTLYS

Charlotte Douglas

Wed 10/29

8:52 am-12:05 pm

2 stops22h 13m

Lyon-Saint Exupéry

Wed 11/5

12:50 pm-6:36 pm

2 stops35h 46m

$585

GreenvilleLyon

GSP - LYS

GSPLYS

Greenville

Wed 10/29

5:36 pm-7:25 pm

2 stops20h 49m

Lyon-Saint Exupéry

Wed 11/5

8:10 pm-11:55 pm

2 stops33h 45m

$590

CharlotteLyon

CLT - LYS

CLTLYS

Charlotte Douglas

Sun 10/19

6:40 pm-12:20 pm

1 stop11h 40m

Lyon-Saint Exupéry

Tue 11/4

8:55 am-4:55 pm

1 stop14h 00m

$591

CharlotteLyon

CLT - LYS

CLTLYS

Charlotte Douglas

Thu 12/4

10:00 am-7:25 pm

2 stops27h 25m

Lyon-Saint Exupéry

Mon 12/8

10:50 am-10:46 pm

2 stops41h 56m

$616

CharlotteLyon

CLT - LYS

CLTLYS

Charlotte Douglas

Wed 11/26

6:40 am-11:05 am

2 stops22h 25m

Lyon-Saint Exupéry

Tue 1/6

10:45 am-8:57 pm

2 stops16h 12m

$652

CharlotteLyon

CLT - LYS

CLTLYS

Charlotte Douglas

Sun 10/19

3:45 pm-11:45 pm

1 stop26h 00m

Lyon-Saint Exupéry

Tue 11/4

12:25 pm-1:31 pm

2 stops31h 06m

$658

CharlotteLyon

CLT - LYS

CLTLYS

Charlotte Douglas

Thu 12/4

2:52 pm-11:05 am

2 stops38h 13m

Lyon-Saint Exupéry

Mon 12/8

1:05 pm-4:55 pm

1 stop33h 50m

$671

GreenvilleLyon

GSP - LYS

GSPLYS

Greenville

Thu 12/4

2:52 pm-11:05 am

2 stops38h 13m

Lyon-Saint Exupéry

Mon 12/8

3:05 pm-11:59 pm

2 stops38h 54m

$680

Flights are sorted by cheapest round-trip flights first.

Deals found on 9/13

Showing 1-10 of 15 results
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Best time to book a flight from South Carolina to Lyon

Have a flexible travel schedule? Discover the best time to fly to Lyon from South Carolina with our price prediction graph.
Estimated round-trip price
Rates are based on past data. Find the cheapest month and day to book your flight based on your travel requirements, then search for cheap deals.

Cheapflights Insights

Everything you need to know about your flight from South Carolina to Lyon

What is the cheapest time of day to fly from SC to LYS?

Find hourly flight availability from South Carolina to Lyon. Discover flight options and departure times throughout the day, allowing you to choose a departure time that suits your schedule. Data last updated September 15, 2025.

When flying from South Carolina to Lyon, the time of day you decide to fly out makes little to no difference towards the overall price you’ll pay on tickets.

Related info for your journey

Find useful and relevant information for your journey from South Carolina to Lyon. Access travel guides, tips, and recommendations to enhance your travel experience. Get information about local attractions, weather, transportation options, and more.

  • What airport do you fly into for flights to Lyon from South Carolina?

    For a flight from South Carolina to Lyon, you will be flying into Lyon-Saint Exupéry. Lyon-Saint Exupéry (LYS) is just 12.5 mi from the center of the city.

  • How long is the flight from South Carolina to Lyon?

    Air Canada, Scandinavian Airlines, and Lufthansa can get you from South Carolina to Lyon in just under 11h 40m. Your travel time can differ by up to 25h 40m. The distance between South Carolina and Lyon is about 4357 mi. This flight may include one or multiple stops.

  • Can I find deals for flights from South Carolina to Lyon that include hotel bookings?

    Yes. In addition to deals on South Carolina to Lyon flights, Cheapflights offers vacation packages that include both flights and hotel.

  • How can I find direct flights from South Carolina to Lyon?

    After entering your origin and destination, apply the non-stop filter on the search result page to find direct flights from South Carolina to Lyon.

  • Can I find deals for business class flights from South Carolina to Lyon?

    Yes. Cheapflights offers flight deals from South Carolina to Lyon by cabin class. In addition to browsing deals, you can also filter by cabin class on the search results page after making a search.

  • What is the cheapest month to book a flight from South Carolina to Lyon?

    Currently, November is the cheapest month in which you can book a flight from South Carolina to Lyon (average of $703). Flying from South Carolina to Lyon in June is currently the most expensive (average of $1,199). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.

See more FAQs

Traveling to a place near Lyon?

Book flights to Lyon if you plan to visit one of these locations
Annemasse
Huez

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Alternative routes for South Carolina to Lyon

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Top airline flying from South Carolina to Lyon

Discover the top airline that operate flights from South Carolina to Lyon. Compare their services, reliability, and customer satisfaction ratings to choose the airline that best suits your travel preferences and needs. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated September 15, 2025.
AirlineCheapestAverageFlexibilityOn-time
DeltaCheapest$720Average$1,313FlexibilityNo cancel feeOn-timeN/A

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