$556+ Cheap flights from South Carolina to Lyon (LYS)
This is the cheapest round-trip flight price found by a Cheapflights user in the last 72 hours by searching for a flight departing on 11/29. Fares are subject to change and may not be available on all flights or dates of travel.
CHS — LYS
Mar 5 — Mar 121
1 adult, Economy
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Find cheap flights from South Carolina to Lyon with Cheapflights
1. Tell us where you want to go
Enter your travel information like dates, passengers, trip type (one-way or round trip), and preferred cabin class then click “Find deals”2. Select your favorite providers
We find the providers serving your travel needs. Choose up to four travel providers to compare side-by-side for flights, hotels, or car rentals.3. Compare prices and book
Review each provider’s pricing and select the best option for you! Book through your favorite provider’s website for a seamless experience.Cheap flight deals from South Carolina to Lyon
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Best
Last-minute
Cheapest flights from South Carolina to LyonExplore the most affordable flight options available from South Carolina to Lyon. Find the lowest fares from popular airlines and budget airlines, with prices last updated on February 3, 2026.
Explore the most affordable flight options available from South Carolina to Lyon. Find the lowest fares from popular airlines and budget airlines, with prices last updated on February 3, 2026.
This United Airlines deal was found by Cheapflights users on 2/3. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 11/296:50 pm
CLT
- LYS
1 stop16h 50m
United Airlines
Tue 12/11:55 pm
LYS
- CLT
2 stops33h 12m
United Airlines
Deal found 2/3![United Airlines logo]()
$556
This Gotogate deal was found by Cheapflights users on 2/3. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Gotogate is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 3/87:50 am
CLT
- LYS
2 stops45h 15m
Air Canada
Tue 3/2412:55 pm
LYS
- CLT
2 stops32h 22m
Air Canada
Deal found 2/3![Air Canada logo]()
$596
This Gotogate deal was found by Cheapflights users on 2/3. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Gotogate is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 3/87:50 pm
CLT
- LYS
1 stop11h 35m
Lufthansa
Tue 3/248:55 am
LYS
- CLT
1 stop14h 00m
Lufthansa
Deal found 2/3![Lufthansa logo]()
$605
This FlightHub deal was found by Cheapflights users on 2/1. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure FlightHub is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 11/296:50 pm
CLT
- LYS
2 stops13h 30m
Multiple Airlines
Tue 12/110:45 am
LYS
- CLT
2 stops16h 14m
Multiple Airlines
Deal found 2/1![Multiple Airlines logo]()
$606
This Flightnetwork deal was found by Cheapflights users on 2/3. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Flightnetwork is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 3/87:50 am
CLT
- LYS
2 stops45h 15m
Multiple Airlines
Tue 3/248:55 am
LYS
- CLT
1 stop14h 00m
Multiple Airlines
Deal found 2/3![Multiple Airlines logo]()
$609
This FlightHub deal was found by Cheapflights users on 2/3. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure FlightHub is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 11/296:50 pm
CLT
- LYS
1 stop11h 35m
Lufthansa
Tue 12/18:55 am
LYS
- CLT
1 stop14h 00m
Lufthansa
Deal found 2/3![Lufthansa logo]()
$617
This United Airlines deal was found by Cheapflights users on 2/3. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 3/87:50 pm
CLT
- LYS
1 stop11h 35m
United Airlines
Tue 3/248:55 am
LYS
- CLT
1 stop14h 00m
United Airlines
Deal found 2/3![United Airlines logo]()
$619
This Delta deal was found by Cheapflights users on 2/3. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 3/210:32 am
CLT
- LYS
2 stops16h 58m
Delta
Wed 3/186:40 am
LYS
- CLT
2 stops20h 53m
Delta
Deal found 2/3![Delta logo]()
$632
This Gotogate deal was found by Cheapflights users on 2/2. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Gotogate is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 12/49:20 am
CLT
- LYS
2 stops19h 45m
Multiple Airlines
Sun 12/1310:45 am
LYS
- CLT
2 stops16h 14m
Multiple Airlines
Deal found 2/2![Multiple Airlines logo]()
$641
This Cheapflightsfares deal was found by Cheapflights users on 2/1. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Cheapflightsfares is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 2/22:55 pm
GSP
- LYS
2 stops13h 10m
Lufthansa
Sat 2/146:20 am
LYS
- GSP
2 stops23h 39m
Lufthansa
Deal found 2/1![Lufthansa logo]()
$728
This United Airlines deal was found by Cheapflights users on 1/31. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 2/256:12 am
GSP
- LYS
2 stops22h 53m
United Airlines
Sun 3/16:10 am
LYS
- GSP
2 stops19h 14m
United Airlines
Deal found 1/31![United Airlines logo]()
$752
This Air Canada deal was found by Cheapflights users on 2/1. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Air Canada is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 2/26:35 am
GSP
- LYS
2 stops22h 30m
Multiple Airlines
Sat 2/141:40 pm
LYS
- GSP
3 stops27h 41m
Multiple Airlines
Deal found 2/1![Multiple Airlines logo]()
$2,472
Best flights from South Carolina to LyonDiscover carefully curated flight deals from South Carolina to Lyon that have cost, travel time, and layovers in mind to ensure you get the best travel experience. Data last updated February 3, 2026.
Discover carefully curated flight deals from South Carolina to Lyon that have cost, travel time, and layovers in mind to ensure you get the best travel experience. Data last updated February 3, 2026.
This Gotogate deal was found by Cheapflights users on 2/3. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Gotogate is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 3/87:50 am
CLT
- LYS
2 stops45h 15m
Air Canada
Tue 3/2412:55 pm
LYS
- CLT
2 stops32h 22m
Air Canada
Deal found 2/3![Air Canada logo]()
$596
This Gotogate deal was found by Cheapflights users on 2/3. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Gotogate is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 3/87:50 pm
CLT
- LYS
1 stop11h 35m
Lufthansa
Tue 3/248:55 am
LYS
- CLT
1 stop14h 00m
Lufthansa
Deal found 2/3![Lufthansa logo]()
$605
This Flightnetwork deal was found by Cheapflights users on 2/3. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Flightnetwork is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 3/87:50 am
CLT
- LYS
2 stops45h 15m
Multiple Airlines
Tue 3/248:55 am
LYS
- CLT
1 stop14h 00m
Multiple Airlines
Deal found 2/3![Multiple Airlines logo]()
$609
This United Airlines deal was found by Cheapflights users on 2/3. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 3/87:50 pm
CLT
- LYS
1 stop11h 35m
United Airlines
Tue 3/248:55 am
LYS
- CLT
1 stop14h 00m
United Airlines
Deal found 2/3![United Airlines logo]()
$619
This Delta deal was found by Cheapflights users on 2/3. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 3/210:32 am
CLT
- LYS
2 stops16h 58m
Delta
Wed 3/186:40 am
LYS
- CLT
2 stops20h 53m
Delta
Deal found 2/3![Delta logo]()
$632
This oojo deal was found by Cheapflights users on 2/2. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure oojo is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 3/167:55 pm
CLT
- LYS
2 stops16h 40m
British Airways
Sat 3/289:45 pm
LYS
- CLT
2 stops42h 14m
British Airways
Deal found 2/2![British Airways logo]()
$728
This Mytrip deal was found by Cheapflights users on 2/2. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Mytrip is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 3/199:40 am
CLT
- LYS
2 stops43h 25m
Multiple Airlines
Thu 3/266:20 am
LYS
- CLT
2 stops22h 37m
Multiple Airlines
Deal found 2/2![Multiple Airlines logo]()
$670
This United Airlines deal was found by Cheapflights users on 2/2. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 3/197:50 pm
CLT
- LYS
1 stop16h 50m
United Airlines
Thu 3/268:55 am
LYS
- CLT
1 stop14h 00m
United Airlines
Deal found 2/2![United Airlines logo]()
$671
This Lufthansa deal was found by Cheapflights users on 2/3. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Lufthansa is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 3/26:50 pm
CLT
- LYS
1 stop16h 50m
Lufthansa
Wed 3/186:25 am
LYS
- CLT
2 stops22h 32m
Lufthansa
Deal found 2/3![Lufthansa logo]()
$722
This United Airlines deal was found by Cheapflights users on 1/31. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 2/256:12 am
GSP
- LYS
2 stops22h 53m
United Airlines
Sun 3/16:10 am
LYS
- GSP
2 stops19h 14m
United Airlines
Deal found 1/31![United Airlines logo]()
$752
This Mytrip deal was found by Cheapflights users on 2/3. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Mytrip is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 3/29:21 am
CLT
- LYS
3 stops26h 44m
Multiple Airlines
Wed 3/188:15 am
LYS
- CLT
3 stops44h 38m
Multiple Airlines
Deal found 2/3![Multiple Airlines logo]()
$837
Last-minute flights from South Carolina to LyonDiscover last-minute flight deals from South Carolina to Lyon. Data last updated February 3, 2026 and is based on user searches.
Discover last-minute flight deals from South Carolina to Lyon. Data last updated February 3, 2026 and is based on user searches.
This Cheapflightsfares deal was found by Cheapflights users on 2/1. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Cheapflightsfares is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 2/22:55 pm
GSP
- LYS
2 stops13h 10m
Lufthansa
Sat 2/146:20 am
LYS
- GSP
2 stops23h 39m
Lufthansa
Deal found 2/1![Lufthansa logo]()
$728
This Air Canada deal was found by Cheapflights users on 2/1. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Air Canada is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 2/26:35 am
GSP
- LYS
2 stops22h 30m
Multiple Airlines
Sat 2/141:40 pm
LYS
- GSP
3 stops27h 41m
Multiple Airlines
Deal found 2/1![Multiple Airlines logo]()
$2,472
This United Airlines deal was found by Cheapflights users on 1/31. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 2/256:12 am
GSP
- LYS
2 stops22h 53m
United Airlines
Sun 3/16:10 am
LYS
- GSP
2 stops19h 14m
United Airlines
Deal found 1/31![United Airlines logo]()
$752
This Delta deal was found by Cheapflights users on 2/3. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 3/210:32 am
CLT
- LYS
2 stops16h 58m
Delta
Wed 3/186:40 am
LYS
- CLT
2 stops20h 53m
Delta
Deal found 2/3![Delta logo]()
$632
This Lufthansa deal was found by Cheapflights users on 2/3. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Lufthansa is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 3/26:50 pm
CLT
- LYS
1 stop16h 50m
Lufthansa
Wed 3/186:25 am
LYS
- CLT
2 stops22h 32m
Lufthansa
Deal found 2/3![Lufthansa logo]()
$722
This Gotogate deal was found by Cheapflights users on 2/3. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Gotogate is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 3/87:50 am
CLT
- LYS
2 stops45h 15m
Air Canada
Tue 3/2412:55 pm
LYS
- CLT
2 stops32h 22m
Air Canada
Deal found 2/3![Air Canada logo]()
$596
This Gotogate deal was found by Cheapflights users on 2/3. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Gotogate is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 3/87:50 pm
CLT
- LYS
1 stop11h 35m
Lufthansa
Tue 3/248:55 am
LYS
- CLT
1 stop14h 00m
Lufthansa
Deal found 2/3![Lufthansa logo]()
$605
This Flightnetwork deal was found by Cheapflights users on 2/3. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Flightnetwork is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 3/87:50 am
CLT
- LYS
2 stops45h 15m
Multiple Airlines
Tue 3/248:55 am
LYS
- CLT
1 stop14h 00m
Multiple Airlines
Deal found 2/3![Multiple Airlines logo]()
$609
This United Airlines deal was found by Cheapflights users on 2/3. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 3/87:50 pm
CLT
- LYS
1 stop11h 35m
United Airlines
Tue 3/248:55 am
LYS
- CLT
1 stop14h 00m
United Airlines
Deal found 2/3![United Airlines logo]()
$619
This oojo deal was found by Cheapflights users on 2/2. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure oojo is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 3/167:55 pm
CLT
- LYS
2 stops16h 40m
British Airways
Sat 3/289:45 pm
LYS
- CLT
2 stops42h 14m
British Airways
Deal found 2/2![British Airways logo]()
$728
This Gotogate deal was found by Cheapflights users on 2/2. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Gotogate is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 3/195:05 pm
CLT
- LYS
2 stops14h 20m
Multiple Airlines
Thu 3/268:55 am
LYS
- CLT
1 stop14h 00m
Multiple Airlines
Deal found 2/2![Multiple Airlines logo]()
$654
This United Airlines deal was found by Cheapflights users on 2/2. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 3/197:50 pm
CLT
- LYS
1 stop16h 50m
United Airlines
Thu 3/268:55 am
LYS
- CLT
1 stop14h 00m
United Airlines
Deal found 2/2![United Airlines logo]()
$671
Find flight deals from South Carolina to Lyon
Keep the following information in mind while searching for South Carolina to Lyon flight deals. Data was last updated February 3, 2026.
Round-trip from | $654 (Gotogate) |
|---|
Cheapflights Fare Finder
Customize your flight search to find flights from South Carolina to Lyon that fit within your specific budget. Explore options based on user searches and filter the results based on your desired price range. Find flights that match your budget for a cost-effective journey. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated February 3, 2026.
Use the filters below to find and compare flights from South Carolina to Lyon that are best for you.
Fly from
South Carolina
Fly to
Lyon
Route
Depart
Return
Price
CharlotteLyon
CLT - LYS
CLTLYS
Charlotte Douglas
Sun 3/8
7:50 am-10:05 am
2 stops45h 15m
Lyon-Saint Exupéry
Tue 3/24
12:55 pm-4:17 pm
2 stops32h 22m
$596
CharlotteLyon
CLT - LYS
CLTLYS
Charlotte Douglas
Sun 3/8
7:50 pm-12:25 pm
1 stop11h 35m
Lyon-Saint Exupéry
Tue 3/24
8:55 am-5:55 pm
1 stop14h 00m
$605
CharlotteLyon
CLT - LYS
CLTLYS
Charlotte Douglas
Sun 3/8
7:50 am-10:05 am
2 stops45h 15m
Lyon-Saint Exupéry
Tue 3/24
8:55 am-5:55 pm
1 stop14h 00m
$609
CharlotteLyon
CLT - LYS
CLTLYS
Charlotte Douglas
Sun 3/8
7:50 pm-12:25 pm
1 stop11h 35m
Lyon-Saint Exupéry
Tue 3/24
8:55 am-5:55 pm
1 stop14h 00m
$619
CharlotteLyon
CLT - LYS
CLTLYS
Charlotte Douglas
Mon 3/2
10:32 am-9:30 am
2 stops16h 58m
Lyon-Saint Exupéry
Wed 3/18
6:40 am-10:33 pm
2 stops20h 53m
$632
CharlotteLyon
CLT - LYS
CLTLYS
Charlotte Douglas
Thu 3/19
9:40 am-10:05 am
2 stops43h 25m
Lyon-Saint Exupéry
Thu 3/26
6:20 am-11:57 pm
2 stops22h 37m
$670
CharlotteLyon
CLT - LYS
CLTLYS
Charlotte Douglas
Thu 3/19
7:50 pm-5:40 pm
1 stop16h 50m
Lyon-Saint Exupéry
Thu 3/26
8:55 am-5:55 pm
1 stop14h 00m
$671
CharlotteLyon
CLT - LYS
CLTLYS
Charlotte Douglas
Mon 3/2
6:50 pm-5:40 pm
1 stop16h 50m
Lyon-Saint Exupéry
Wed 3/18
6:25 am-11:57 pm
2 stops22h 32m
$722
CharlotteLyon
CLT - LYS
CLTLYS
Charlotte Douglas
Mon 3/16
7:55 pm-5:35 pm
2 stops16h 40m
Lyon-Saint Exupéry
Sat 3/28
9:45 pm-10:59 am
2 stops42h 14m
$728
GreenvilleLyon
GSP - LYS
GSPLYS
Greenville
Wed 2/25
6:12 am-11:05 am
2 stops22h 53m
Lyon-Saint Exupéry
Sun 3/1
6:10 am-7:24 pm
2 stops19h 14m
$752
Showing 1-10 of 11 results
Best time to book a flight from South Carolina to Lyon
Have a flexible travel schedule? Discover the best time to fly to Lyon from South Carolina with our price prediction graph.
CLT-LYS
GSP-LYS
Estimated round-trip price
Rates are based on past data. Find the cheapest month and day to book your flight based on your travel requirements, then search for cheap deals.
Cheapflights Insights
Everything you need to know about your flight from South Carolina to Lyon
USSC-LYS
CLT-LYS
GSP-LYS
No data available for this route at this time. Please check back soon.
Related info for your journey
Find useful and relevant information for your journey from South Carolina to Lyon. Access travel guides, tips, and recommendations to enhance your travel experience. Get information about local attractions, weather, transportation options, and more.
Traveling to a place near Lyon?
Book flights to Lyon if you plan to visit one of these locationsAnnemasse
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