Regardless of the time of day you decide to fly, the ticket price will remain around the same. Book flights from Washington Reagan-National Airport to Lyon as you normally would.
To save up to 12% on this flight, we recommend booking at least 61 days prior to travel. The price may fluctuate and will likely increase closer to your departure date. Users on Cheapflights have found tickets from Washington Reagan-National Airport to Lyon from $903 1-2 weeks out and tickets from $903 for flights departing within the next 72 hours.