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$316+ Cheap flights from Des Moines (DSM) to Luxembourg

This is the cheapest one-way flight price found by a Cheapflights user in the last 72 hours by searching for a flight departing on 11/3. Fares are subject to change and may not be available on all flights or dates of travel.
DSM — LUX
juin 17 — juin 241
mar. 6/17
mar. 6/24
1 adult, Economy
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Cheap flight deals from Des Moines to Luxembourg

Keep the following information in mind while searching for Des Moines to Luxembourg flight deals. Data was last updated juin 12, 2025.

Round-trip from

$672
(American Airlines)

One-way from

$316
(Kiwi.com)
From Des Moines to Luxembourg
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One-way flight from Des Moines to Luxembourg
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Find flight deals from Des Moines to Luxembourg

Cheapest flights from Des Moines to Luxembourg
Explore the most affordable flight options available from Des Moines to Luxembourg. Find the lowest fares from popular airlines and budget airlines, with prices last updated on juin 12, 2025.

This American Airlines deal was found by Cheapflights users on 6/9. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
lun. 9/16:12 pmDSM - LUX
2 stops20h 08mAmerican Airlines
mar. 9/910:05 pmLUX - DSM
2 stops29h 15mAmerican Airlines
Deal found 6/9$672
This lastminute.com deal was found by Cheapflights users on 6/10. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure lastminute.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
mer. 7/2311:24 amDSM - LUX
2 stops16h 11mMultiple Airlines
mer. 7/306:10 amLUX - DSM
2 stops21h 47mMultiple Airlines
Deal found 6/10$924
This Gotogate deal was found by Cheapflights users on 6/11. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Gotogate is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
jeu. 7/246:50 pmDSM - LUX
2 stops17h 45mLufthansa
jeu. 7/316:15 amLUX - DSM
2 stops23h 45mLufthansa
Deal found 6/11$961
This Booking.com deal was found by Cheapflights users on 6/9. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Booking.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
lun. 9/18:00 amDSM - LUX
3 stops19h 00mAir Canada
mar. 9/92:30 pmLUX - DSM
3 stops28h 53mAir Canada
Deal found 6/9$1,125
This United Airlines deal was found by Cheapflights users on 6/10. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
sam. 7/266:50 pmDSM - LUX
2 stops31h 25mUnited Airlines
sam. 8/29:50 amLUX - DSM
2 stops42h 57mUnited Airlines
Deal found 6/10$1,146
This Delta deal was found by Cheapflights users on 6/10. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
ven. 7/256:05 amDSM - LUX
2 stops20h 55mDelta
ven. 8/16:05 amLUX - DSM
2 stops17h 35mDelta
Deal found 6/10$1,179

Cheapflights Fare Finder

Customize your flight search to find flights from Des Moines to Luxembourg that fit within your specific budget. Explore options based on user searches and filter the results based on your desired price range. Find flights that match your budget for a cost-effective journey. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated juin 12, 2025.
Use the filters below to find and compare flights from Des Moines to Luxembourg that are best for you.

Fly from

Des Moines

Fly to

Luxembourg

Route

Depart

Return

Price

Des MoinesLuxembourg

DSM - LUX

DSMLUX

Des Moines

lun. 9/1

6:12 pm-9:20 pm

2 stops20h 08m

Luxembourg

mar. 9/9

10:05 pm-8:20 pm

2 stops29h 15m

$672

Des MoinesLuxembourg

DSM - LUX

DSMLUX

Des Moines

mer. 7/23

11:24 am-10:35 am

2 stops16h 11m

Luxembourg

mer. 7/30

6:10 am-8:57 pm

2 stops21h 47m

$924

Des MoinesLuxembourg

DSM - LUX

DSMLUX

Des Moines

jeu. 7/24

6:50 pm-7:35 pm

2 stops17h 45m

Luxembourg

jeu. 7/31

6:15 am-11:00 pm

2 stops23h 45m

$961

Des MoinesLuxembourg

DSM - LUX

DSMLUX

Des Moines

lun. 9/1

8:00 am-10:00 am

3 stops19h 00m

Luxembourg

mar. 9/9

2:30 pm-12:23 pm

3 stops28h 53m

$1,125

Des MoinesLuxembourg

DSM - LUX

DSMLUX

Des Moines

sam. 7/26

6:50 pm-9:15 am

2 stops31h 25m

Luxembourg

sam. 8/2

9:50 am-9:47 pm

2 stops42h 57m

$1,146

Des MoinesLuxembourg

DSM - LUX

DSMLUX

Des Moines

ven. 7/25

6:05 am-10:00 am

2 stops20h 55m

Luxembourg

ven. 8/1

6:05 am-4:40 pm

2 stops17h 35m

$1,179

Des MoinesLuxembourg

DSM - LUX

DSMLUX

Des Moines

lun. 11/3

8:30 am-3:55 pm

2 stops24h 25m

$316

Des MoinesLuxembourg

DSM - LUX

DSMLUX

Des Moines

dim. 11/2

5:52 pm-4:20 pm

2 stops15h 28m

$450

Des MoinesLuxembourg

DSM - LUX

DSMLUX

Des Moines

mar. 11/4

5:25 pm-1:50 pm

2 stops13h 25m

$464

Des MoinesLuxembourg

DSM - LUX

DSMLUX

Des Moines

mer. 11/5

6:50 pm-4:10 pm

2 stops14h 20m

$468

Flights are sorted by cheapest round-trip flights first.

Deals found on 6/12

Showing 1-10 of 12 results
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Best time to book a flight from Des Moines to Luxembourg

Have a flexible travel schedule? Discover the best time to fly to Luxembourg from Des Moines with our price prediction graph.
Estimated round-trip price
Rates are based on past data. Find the cheapest month and day to book your flight based on your travel requirements, then search for cheap deals.

Cheapflights Insights

Everything you need to know about your flight from Des Moines to Luxembourg

Rainfall in Luxembourg by month

Plan your trip to Luxembourg by taking into account the average rainfall totals by month.

In terms of precipitation, rainfall in Luxembourg ranges from 2.0 - 2.8 inches per month. November is typically the wettest month, when rainfall can reach 2.8 in. February is typically the driest time to visit Luxembourg when rainfall is around 2.0 in.

Temperature in Luxembourg by month

Plan your trip to Luxembourg by taking into account the average temperature totals by month.

If weather is an important factor for your trip to Luxembourg, use this chart to help with planning. For those seeking warmer temperatures, July is the ideal time of year to visit, when temperatures reach an average of 62.6 F. Travelers looking to avoid the cold should look outside of January, when temperatures are typically at their lowest (around 32.0 F).

Reviews of airlines servicing Luxembourg

Get insights into the airlines that provide service to Luxembourg. Read reviews, discover amenities, and learn about the overall travel experience offered by airlines. Use this information to make informed decisions when choosing an airline for your flight to Luxembourg. Reviews last updated juin 12, 2025.
Delta
8.0
Very good
7,950 reviews

Food

7.3

Boarding

8.2

Entertainment

7.9

Overall

8.0

Comfort

7.9

Crew

8.5

Reviews

1 / 20
10.0
Excellent

Kim,May 2025

PIH - SLC

This trip was fine even with delay I had plenty of time to get connection flight!
Delta
8.0
Very good
7,950 reviews
Delta
8.0
Very good
7,950 reviews

Food

7.3

Boarding

8.2

Entertainment

7.9

Overall

8.0

Comfort

7.9

Crew

8.5

Reviews

1 / 20
10.0
Excellent

Kim,May 2025

PIH - SLC

This trip was fine even with delay I had plenty of time to get connection flight!
Air France
7.5
Good
1,463 reviews
Delta
8.0
Very good
7,950 reviews

Food

7.3

Boarding

8.2

Entertainment

7.9

Overall

8.0

Comfort

7.9

Crew

8.5

Reviews

1 / 20
10.0
Excellent

Kim,May 2025

PIH - SLC

This trip was fine even with delay I had plenty of time to get connection flight!
United Airlines
7.4
Good
8,790 reviews
Delta
8.0
Very good
7,950 reviews

Food

7.3

Boarding

8.2

Entertainment

7.9

Overall

8.0

Comfort

7.9

Crew

8.5

Reviews

1 / 20
10.0
Excellent

Kim,May 2025

PIH - SLC

This trip was fine even with delay I had plenty of time to get connection flight!
American Airlines
7.2
Good
10,000 reviews
Delta
8.0
Very good
7,950 reviews

Food

7.3

Boarding

8.2

Entertainment

7.9

Overall

8.0

Comfort

7.9

Crew

8.5

Reviews

1 / 20
10.0
Excellent

Kim,May 2025

PIH - SLC

This trip was fine even with delay I had plenty of time to get connection flight!
Air Canada
7.1
Good
9,531 reviews
Delta
8.0
Very good
7,950 reviews

Food

7.3

Boarding

8.2

Entertainment

7.9

Overall

8.0

Comfort

7.9

Crew

8.5

Reviews

1 / 20
10.0
Excellent

Kim,May 2025

PIH - SLC

This trip was fine even with delay I had plenty of time to get connection flight!

Related info for your journey

Find useful and relevant information for your journey from Des Moines to Luxembourg. Access travel guides, tips, and recommendations to enhance your travel experience. Get information about local attractions, weather, transportation options, and more.

  • What airport do you fly from for flights from Des Moines to Luxembourg?

    Most people fly from Des Moines (DSM) if they book a flight from Des Moines to Luxembourg. Des Moines is conveniently located just 3.6 mi from Des Moines’s city center.

  • What are the cheapest airlines to fly from Des Moines to Luxembourg one-way?

    The cheapest airlines for a one-way flight from Des Moines to Luxembourg are American Airlines ($450), Air France ($464), and Lufthansa ($468).

  • Can I find deals for flights from Des Moines to Luxembourg that include hotel bookings?

    Yes. In addition to deals on Des Moines to Luxembourg flights, Cheapflights offers vacation packages that include both flights and hotel.

  • How can I find direct flights from Des Moines to Luxembourg?

    After entering your origin and destination, apply the non-stop filter on the search result page to find direct flights from Des Moines to Luxembourg.

  • Can I find deals for business class flights from Des Moines to Luxembourg?

    Yes. Cheapflights offers flight deals from Des Moines to Luxembourg by cabin class. In addition to browsing deals, you can also filter by cabin class on the search results page after making a search.

  • What is the cheapest month to book a flight from Des Moines to Luxembourg?

    Currently, February is the cheapest month in which you can book a flight from Des Moines to Luxembourg (average of $638). Flying from Des Moines to Luxembourg in June is currently the most expensive (average of $1,187). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.

See more FAQs

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