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$395+ Cheap flights from Des Moines (DSM) to Lucerne, Switzerland

This is the cheapest one-way flight price found by a Cheapflights user in the last 72 hours by searching for a flight departing on 1/30. Fares are subject to change and may not be available on all flights or dates of travel.
DSM — ZRH
Jan 16 — Jan 231
Fri 1/16
Fri 1/23
1 adult, Economy
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Cheap flight deals from Des Moines to Lucerne

Cheapest flights from Des Moines to Lucerne
Explore the most affordable flight options available from Des Moines to Lucerne. Find the lowest fares from popular airlines and budget airlines, with prices last updated on December 17, 2025.

This United Airlines deal was found by Cheapflights users on 12/16. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 12/313:14 pmDSM - ZRH
2 stops13h 41mUnited Airlines
Tue 1/61:00 pmZRH - DSM
2 stops35h 47mUnited Airlines
Deal found 12/16$1,179
This Air Canada deal was found by Cheapflights users on 12/16. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Air Canada is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 12/318:00 amDSM - ZRH
2 stops19h 25mMultiple Airlines
Tue 1/67:05 amZRH - DSM
3 stops21h 45mMultiple Airlines
Deal found 12/16$1,431
This Air Canada deal was found by Cheapflights users on 12/16. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Air Canada is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 12/313:14 pmDSM - ZRH
3 stops18h 31mAir Canada
Tue 1/67:05 amZRH - DSM
3 stops21h 45mAir Canada
Deal found 12/16$3,039

Find flight deals from Des Moines to Lucerne

Keep the following information in mind while searching for Des Moines to Lucerne flight deals. Data was last updated December 17, 2025.

Most accurate provider

eDreams
3 stars

Most trusted provider

eDreams
3 stars

Round-trip from

$424
(Ticket)

One-way from

$395
(United Airlines)

Popular in

June

Cheapest in

January

Average price

$1,237
Provider with most accurate pricing for Des Moines-Zurich flight deals.
Search Deals
Provider most trusted by Cheapflights users for Des Moines-Zurich flights.
Search Deals
From Des Moines to Lucerne
Search Deals
One-way flight from Des Moines to Lucerne
Search Deals
Highest demand for flights based on searches. 26% potential increase in price ($341 potential increase over avg. RT price).
Search Deals
Cheapest flight prices on average. 7% potential price decrease ($63 potential savings vs. average RT price).
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Average for round-trip flights in December 2025
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Cheapflights Fare Finder

 
Customize your flight search to find flights from Des Moines to Lucerne that fit within your specific budget. Explore options based on user searches and filter the results based on your desired price range. Find flights that match your budget for a cost-effective journey. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated December 17, 2025.
Use the filters below to find and compare flights from Des Moines to Lucerne that are best for you.

Fly from

Des Moines

Fly to

Lucerne

Route

Depart

Return

Price

Des MoinesZurich

DSM - ZRH

DSMZRH

Des Moines

Thu 1/29

8:00 am-10:25 am

2 stops19h 25m

Zurich

Thu 2/5

1:20 pm-2:33 pm

2 stops32h 13m

$424

Des MoinesZurich

DSM - ZRH

DSMZRH

Des Moines

Fri 1/30

6:48 pm-4:30 pm

2 stops14h 42m

Zurich

Fri 2/6

8:55 am-9:50 pm

2 stops19h 55m

$464

Des MoinesZurich

DSM - ZRH

DSMZRH

Des Moines

Fri 1/30

3:04 pm-2:45 pm

2 stops16h 41m

Zurich

Fri 2/6

1:20 pm-2:33 pm

2 stops32h 13m

$484

Des MoinesZurich

DSM - ZRH

DSMZRH

Des Moines

Tue 2/17

3:24 pm-11:55 am

2 stops13h 31m

Zurich

Fri 2/27

1:20 pm-10:15 pm

2 stops39h 55m

$484

Des MoinesZurich

DSM - ZRH

DSMZRH

Des Moines

Fri 2/6

8:00 am-2:45 pm

2 stops23h 45m

Zurich

Tue 2/10

1:00 pm-2:33 pm

2 stops32h 33m

$484

Des MoinesZurich

DSM - ZRH

DSMZRH

Des Moines

Tue 1/13

3:35 pm-2:45 pm

2 stops16h 10m

Zurich

Tue 1/20

1:00 pm-2:33 pm

2 stops32h 33m

$484

Des MoinesZurich

DSM - ZRH

DSMZRH

Des Moines

Fri 1/30

1:35 pm-2:45 pm

2 stops18h 10m

$395

Des MoinesZurich

DSM - ZRH

DSMZRH

Des Moines

Fri 1/30

11:30 am-11:55 am

3 stops17h 25m

$1,299

Flights are sorted by cheapest round-trip flights first.

Deals found on 12/16

Best time to book a flight from Des Moines to Lucerne

Have a flexible travel schedule? Discover the best time to fly to Lucerne from Des Moines with our price prediction graph.
Estimated round-trip price
Rates are based on past data. Find the cheapest month and day to book your flight based on your travel requirements, then search for cheap deals.

Cheapflights Insights

Everything you need to know about your flight from Des Moines to Lucerne

What is the cheapest month to book a flight from Des Moines to Lucerne?

Currently, February is the cheapest month in which you can book a flight from Des Moines to Lucerne (average of $528). Flying from Des Moines to Lucerne in June is currently the most expensive (average of $1,481). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.

How much does it cost to fly round-trip from Des Moines to Lucerne?

Reviews of airlines servicing Lucerne

Get insights into the airlines that provide service to Lucerne. Read reviews, discover amenities, and learn about the overall travel experience offered by airlines. Use this information to make informed decisions when choosing an airline for your flight to Lucerne. Reviews last updated December 17, 2025.
See what other customers who have flown with United Airlines from Des Moines to Lucerne have to say. You can also see how each airline compares in terms of entertainment options, comfort, food, crew/service, and boarding process.
United Airlines
7.4
Good
9,092 reviews

Overall

7.4

Crew

8.1

Comfort

7.3

Entertainment

7.1

Food

6.6

Boarding

7.7

Reviews

1 / 20
10.0
Excellent

Sunderesh,Dec 2025

AUS - EWR

Smooth flight from Austin to Newark. The crew was friendly.
United Airlines
7.4
Good
9,092 reviews
United Airlines
7.4
Good
9,092 reviews

Overall

7.4

Crew

8.1

Comfort

7.3

Entertainment

7.1

Food

6.6

Boarding

7.7

Reviews

1 / 20
10.0
Excellent

Sunderesh,Dec 2025

AUS - EWR

Smooth flight from Austin to Newark. The crew was friendly.

Related info for your journey

Find useful and relevant information for your journey from Des Moines to Lucerne. Access travel guides, tips, and recommendations to enhance your travel experience. Get information about local attractions, weather, transportation options, and more.

  • What airport do you fly from for flights from Des Moines to Lucerne?

    Located just 3.6 mi from the city center, Des Moines is the airport most travelers will use when flying to Lucerne from Des Moines. Booking flights from Des Moines (DSM) to Lucerne should be relatively easy as there are 0 daily outbound flights to Lucerne from 1 airline.

  • How long is the flight from Des Moines to Lucerne?

    Airlines like Air Canada and United Airlines fly from Des Moines to Lucerne in about 16h 41m. The time it takes to get you to your destination can typically vary by up to 2h 44m. The distance from Des Moines to Lucerne is about 4666 mi. When browsing for deals, the options you’ll see will be for both nonstop flights and flights with stops.

  • Can I find deals for flights from Des Moines to Lucerne that include hotel bookings?

    Yes. In addition to deals on Des Moines to Lucerne flights, Cheapflights offers vacation packages that include both flights and hotel.

  • How can I find direct flights from Des Moines to Lucerne?

    After entering your origin and destination, apply the non-stop filter on the search result page to find direct flights from Des Moines to Lucerne.

  • Can I find deals for business class flights from Des Moines to Lucerne?

    Yes. Cheapflights offers flight deals from Des Moines to Lucerne by cabin class. In addition to browsing deals, you can also filter by cabin class on the search results page after making a search.

  • What is the cheapest month to book a flight from Des Moines to Lucerne?

    Currently, February is the cheapest month in which you can book a flight from Des Moines to Lucerne (average of $528). Flying from Des Moines to Lucerne in June is currently the most expensive (average of $1,481). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.

See more FAQs

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Top airline flying from Des Moines to Lucerne

Discover the top airline that operate flights from Des Moines to Lucerne. Compare their services, reliability, and customer satisfaction ratings to choose the airline that best suits your travel preferences and needs. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated December 17, 2025.
AirlineCheapestAverageFlexibilityOn-time
United AirlinesCheapest$602Average$896FlexibilityNo cancel feeOn-time69%

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