Louisville

$325+ Cheap flights from Portland, ME to Louisville (PWM - SDF)

PWM — SDF
Dec 10 — Dec 171
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1. Tell us where you want to go

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2. Select your favorite providers

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Cheap flight deals from Portland to Louisville

Cheapest flights from Portland to Louisville

Thu 11/268:08 am -
1 stop5h 10m
Fri 11/276:00 am -
1 stop4h 07m
Deal found 11/5$325
Fri 12/44:53 pm -
1 stop4h 24m
Sun 12/65:58 pm -
1 stop5h 22m
Deal found 11/5$359
Fri 11/274:50 pm -
1 stop4h 23m
Wed 12/27:41 am -
1 stop4h 16m
Deal found 11/5$396
Thu 11/265:50 am -
1 stop7h 13m
Tue 12/19:55 am -
1 stop4h 42m
Deal found 11/5$425
Thu 11/268:08 am -
1 stop5h 10m
Wed 12/29:55 am -
2 stops9h 30m
Deal found 11/5$430
Fri 11/278:49 am -
2 stops10h 41m
Tue 12/12:25 pm -
2 stops8h 59m
Deal found 11/5$435
Sun 11/226:27 am -
1 stop7h 36m
Wed 12/25:58 pm -
1 stop5h 22m
Deal found 11/5$436
Wed 12/26:00 am -
1 stop7h 23m
Sat 12/52:05 pm -
1 stop5h 20m
Deal found 11/7$447
Fri 12/410:25 am -
2 stops10h 10m
Sun 12/65:40 am -
1 stop4h 50m
Deal found 11/5$453

Find flight deals from Portland to Louisville

Most accurate provider

FlightHub
3 stars

Most trusted provider

FlightHub
3 stars

Round-trip from

$287
(Kiwi.com)

Popular in

October

Cheapest in

September

Average price

$451
Provider with most accurate pricing for Portland-Louisville Intl flight deals.
Provider most trusted by Cheapflights users for Portland-Louisville Intl flights.
From Portland to Louisville Intl
Highest demand for flights based on searches. 0% potential increase in price ($1 potential increase over avg. RT price).
Cheapest flight prices on average. 1% potential price decrease ($6 potential savings vs. average RT price).
Average for round-trip flights in November 2026

Cheapflights Fare Finder

 
Use the filters below to find and compare flights from Portland to Louisville that are best for you.

Fly from

Fly to

Route

Depart

Return

Price

Cheapest round-trip

PortlandLouisville

PWM Portland - SDF Louisville Intl

PWMSDF

Portland

Fri 12/4

4:53 pm-9:17 pm

1 stop4h 24m

Louisville Intl

Sun 12/6

5:58 pm-11:20 pm

1 stop5h 22m

$359

PortlandLouisville

PWM Portland - SDF Louisville Intl

PWMSDF

Portland

Sun 1/24

7:30 am-2:44 pm

2 stops7h 14m

Louisville Intl

Mon 2/1

7:00 am-2:33 pm

2 stops7h 33m

$369

PortlandLouisville

PWM Portland - SDF Louisville Intl

PWMSDF

Portland

Sun 11/29

12:55 pm-10:45 pm

2 stops9h 50m

Louisville Intl

Wed 12/31

12:00 am-12:00 am

Nonstop0h 00m

$377
Quickest round-trip

PortlandLouisville

PWM Portland - SDF Louisville Intl

PWMSDF

Portland

Sun 11/29

5:08 pm-10:30 pm

1 stop5h 22m

Louisville Intl

Wed 12/31

12:00 am-12:00 am

Nonstop0h 00m

$419

PortlandLouisville

PWM Portland - SDF Louisville Intl

PWMSDF

Portland

Wed 4/28

4:50 pm-9:41 pm

1 stop4h 51m

Louisville Intl

Wed 5/5

10:15 am-4:13 pm

1 stop5h 58m

$421

PortlandLouisville

PWM Portland - SDF Louisville Intl

PWMSDF

Portland

Wed 12/2

7:00 am-6:17 pm

2 stops11h 17m

Louisville Intl

Sat 12/5

9:00 am-3:38 pm

1 stop6h 38m

$430

PortlandLouisville

PWM Portland - SDF Louisville Intl

PWMSDF

Portland

Sat 12/19

1:00 pm-11:40 pm

2 stops10h 40m

Louisville Intl

Tue 12/29

5:40 am-9:50 am

1 stop4h 10m

$490

PortlandLouisville

PWM Portland - SDF Louisville Intl

PWMSDF

Portland

Sun 12/20

5:20 pm-12:30 am

1 stop7h 10m

Louisville Intl

Sat 12/26

5:40 am-9:25 am

1 stop3h 45m

$505

PortlandLouisville

PWM Portland - SDF Louisville Intl

PWMSDF

Portland

Sun 11/29

3:24 pm-10:30 pm

1 stop7h 06m

Louisville Intl

Wed 12/31

12:00 am-12:00 am

Nonstop0h 00m

$507

PortlandLouisville

PWM Portland - SDF Louisville Intl

PWMSDF

Portland

Fri 11/27

5:20 am-3:25 pm

2 stops10h 05m

Louisville Intl

Thu 12/3

12:55 pm-9:50 pm

2 stops8h 55m

$512

Flights are sorted by cheapest round-trip flights first.

Deals found on 11/9

Showing 1-10 of 13 resultsSorted by cheapest first
1
2

Compare providers for flights from Portland to Louisville

Use the table below to compare price accuracy, trust ratings, and cancellation policies for each provider offering flight deals from Portland to Louisville in November.
ProviderPrice AccuracyTrust Score*
ExpediaPrice Accuracy1 starTrust Score*3 stars
FlightHubPrice Accuracy3 starsTrust Score*3 stars
eDreamsPrice Accuracy2 starsTrust Score*3 stars

*The Trust Score is based on feedback from users after their booking experience. It measures overall satisfaction, helping us identify issues like hidden fees, problems during the ticketing process, and the quality of customer service. This score is our best indicator of the provider's quality and reliability.

  • Most accurate provider: When it comes to deals on Portland, Maine-Louisville flights, users find the pricing of FlightHub to be most consistent on Cheapflights vs. FlightHub Users can find the same prices on Portland, Maine-Louisville flight deals on Cheapflights vs. FlightHub >95% of the time. Price accuracy is based on data collected from Portland, Maine-Louisville flight searches over the past month and is updated monthly.
  • Most trusted provider: When it comes to deals on Portland, Maine-Louisville flights, Cheapflights users trust FlightHub the most. FlightHub has received a user feedback score of 3 out of 3 stars (3 being the best), meaning they have been trusted the most by Cheapflights users looking for Portland, Maine-Louisville flight deals. Provider user feedback score is based on Cheapflights searches over the past month and is updated monthly.

Best time to book a flight from Portland to Louisville

Have a flexible travel schedule? Discover the best time to fly to Louisville from Portland with our price prediction graph.
Estimated round-trip price

Cheapflights Insights

Everything you need to know about your flight from Portland to Louisville

How much does it cost to fly round-trip from Portland, Maine to Louisville?

Airfare is below average for this route at the moment.

Portland, Maine to Louisville flights typically cost between $451 and $701 in January.
The cheapest round-trip price found within the last 5 days was $287 on Multiple Airlines (Jan 24-Feb 1).

Reviews of airlines servicing Louisville

Read reviews from past customers who have flown Southwest,Delta, andUnited Airlines from Portland to Louisville. Users can see the overall rating for each airline as well as how each is rated in terms of entertainment options, comfort, food, crew/service, and boarding process.

Comfort

8.0

Entertainment

7.4

Food

7.0

Overall

8.0

Boarding

8.1

Crew

8.6

Reviews

1 / 20
8.0
Excellent

Patricia,Oct 2026

DAL - TPA

I love flying southwest, Both flights were packed full full - so not room for all carry one and bags had to be checked but still good flights.

Comfort

8.0

Entertainment

7.4

Food

7.0

Overall

8.0

Boarding

8.1

Crew

8.6

Reviews

1 / 20
8.0
Excellent

Patricia,Oct 2026

DAL - TPA

I love flying southwest, Both flights were packed full full - so not room for all carry one and bags had to be checked but still good flights.

Comfort

8.0

Entertainment

7.4

Food

7.0

Overall

8.0

Boarding

8.1

Crew

8.6

Reviews

1 / 20
8.0
Excellent

Patricia,Oct 2026

DAL - TPA

I love flying southwest, Both flights were packed full full - so not room for all carry one and bags had to be checked but still good flights.

Comfort

8.0

Entertainment

7.4

Food

7.0

Overall

8.0

Boarding

8.1

Crew

8.6

Reviews

1 / 20
8.0
Excellent

Patricia,Oct 2026

DAL - TPA

I love flying southwest, Both flights were packed full full - so not room for all carry one and bags had to be checked but still good flights.

Comfort

8.0

Entertainment

7.4

Food

7.0

Overall

8.0

Boarding

8.1

Crew

8.6

Reviews

1 / 20
8.0
Excellent

Patricia,Oct 2026

DAL - TPA

I love flying southwest, Both flights were packed full full - so not room for all carry one and bags had to be checked but still good flights.

Related info for your journey

  • How long is the flight from Portland, Maine to Louisville?

    There are many flights that can get you from Portland, Maine to Louisville in 4h 24m. Fly via Delta or United Airlines to get the fastest option. Portland, Maine and Louisville are separated by a distance of 887 mi. This flight may include one or multiple stops.

  • What are the cheapest airlines flying from Portland, Maine to Louisville round-trip?

    Cheapflights users have booked flights from Portland, Maine to Louisville round-trip from $288. Other airlines that can offer you cheap pricing are Delta, from $289, and United Airlines, from $306. Southwest is 36% cheaper than the average price of flights available within the next 90 days to this destination.

  • Can I find deals for flights from Portland to Louisville that include hotel bookings?

    Yes. In addition to deals on Portland to Louisville flights, Cheapflights offers vacation packages that include both flights and hotel.

  • How can I find direct flights from Portland to Louisville?

    After entering your origin and destination, apply the non-stop filter on the search result page to find direct flights from Portland to Louisville.

  • Can I find deals for business class flights from Portland to Louisville?

    Yes. Cheapflights offers flight deals from Portland to Louisville by cabin class. In addition to browsing deals, you can also filter by cabin class on the search results page after making a search.

See more FAQs

Traveling to a place near Louisville?

Book flights to Louisville if you plan to visit one of these locations
Shepherdsville
Elizabethtown
Jeffersonville

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Top 4 airlines flying from Portland to Louisville

AirlineCheapestAverageFlexibilityOn-time
SouthwestCheapest$288Average$469FlexibilityNo cancel feeOn-time63%
DeltaCheapest$289Average$446FlexibilityNo cancel feeOn-timeN/A
United AirlinesCheapest$306Average$451FlexibilityNo cancel feeOn-time69%
American AirlinesCheapest$316Average$450FlexibilityNo cancel feeOn-time71%

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