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Santo Domingo

$179+ Cheap flights from Portland, ME (PWM) to Santo Domingo (SDQ)

This is the cheapest one-way flight price found by a Cheapflights user in the last 72 hours by searching for a flight departing on 9/9. Fares are subject to change and may not be available on all flights or dates of travel.
PWM — SDQ
Jun 21 — Jun 281
Sun 6/21
Sun 6/28
1 adult, Economy
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Cheap flight deals from Portland to Santo Domingo

Cheapest flights from Portland to Santo Domingo
Explore the most affordable flight options available from Portland to Santo Domingo. Find the lowest fares from popular airlines and budget airlines, with prices last updated on May 22, 2026.

This Delta deal was found by Cheapflights users on 5/22. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 6/56:25 am
PWM
-
SDQ
1 stop11h 36m
Delta
Tue 6/96:06 am
SDQ
-
PWM
1 stop8h 13m
Delta
Deal found 5/22$376
This American Airlines deal was found by Cheapflights users on 5/22. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 6/56:54 pm
PWM
-
SDQ
2 stops18h 21m
American Airlines
Tue 6/97:35 pm
SDQ
-
PWM
2 stops17h 04m
American Airlines
Deal found 5/22$381
This United Airlines deal was found by Cheapflights users on 5/17. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 11/26:00 am
PWM
-
SDQ
1 stop16h 46m
United Airlines
Fri 11/64:18 pm
SDQ
-
PWM
1 stop7h 39m
United Airlines
Deal found 5/17$496
This Delta deal was found by Cheapflights users on 5/18. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 6/266:00 am
PWM
-
SDQ
1 stop7h 16m
Delta
Thu 7/22:05 pm
SDQ
-
PWM
1 stop10h 47m
Delta
Deal found 5/18$534
This JetBlue deal was found by Cheapflights users on 5/19. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure JetBlue is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 10/36:00 am
PWM
-
SDQ
1 stop11h 55m
JetBlue
Tue 10/63:35 pm
SDQ
-
PWM
1 stop8h 17m
JetBlue
Deal found 5/19$600
This American Airlines deal was found by Cheapflights users on 5/18. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 6/266:54 pm
PWM
-
SDQ
1 stop17h 51m
American Airlines
Thu 7/210:27 am
SDQ
-
PWM
2 stops12h 06m
American Airlines
Deal found 5/18$630

Find flight deals from Portland to Santo Domingo

Discover tips and strategies to find the most affordable flight options for your journey from Portland (PWM) to Santo Domingo (SDQ). Learn about various techniques such as flexible date searches, comparing prices across and setting up price alerts. Use these methods to find the cheapest flights available for your travel needs. Data last updated May 22, 2026.

Most accurate provider

FlightHub
3 stars

Most trusted provider

FlightHub
3 stars

Round-trip from

$435
(Delta)

One-way from

$179
(American Airlines)
Provider with most accurate pricing for Portland-Santo Domingo Las Americas flight deals.
Search Deals
Provider most trusted by Cheapflights users for Portland-Santo Domingo Las Americas flights.
Search Deals
From Portland to Santo Domingo Las Americas
Search Deals
One-way flight from Portland to Santo Domingo Las Americas
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Cheapflights Fare Finder

 
Customize your flight search to find flights from Portland to Santo Domingo that fit within your specific budget. Explore options based on user searches and filter the results based on your desired price range. Find flights that match your budget for a cost-effective journey. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated May 22, 2026.
Use the filters below to find and compare flights from Portland to Santo Domingo that are best for you.

Fly from

Fly to

Route

Depart

Return

Price

Cheapest round-trip

PortlandSanto Domingo

PWM - SDQ

PWMSDQ

Portland

Fri 6/5

6:25 am-6:01 pm

1 stop11h 36m

Santo Domingo Las Americas

Tue 6/9

6:06 am-2:19 pm

1 stop8h 13m

$376

PortlandSanto Domingo

PWM - SDQ

PWMSDQ

Portland

Fri 6/5

6:54 pm-1:15 pm

2 stops18h 21m

Santo Domingo Las Americas

Tue 6/9

7:35 pm-12:39 pm

2 stops17h 04m

$381

PortlandSanto Domingo

PWM - SDQ

PWMSDQ

Portland

Mon 11/2

6:00 am-11:46 pm

1 stop16h 46m

Santo Domingo Las Americas

Fri 11/6

4:18 pm-10:57 pm

1 stop7h 39m

$496

PortlandSanto Domingo

PWM - SDQ

PWMSDQ

Portland

Fri 6/26

6:00 am-1:16 pm

1 stop7h 16m

Santo Domingo Las Americas

Thu 7/2

2:05 pm-12:52 am

1 stop10h 47m

$534

PortlandSanto Domingo

PWM - SDQ

PWMSDQ

Portland

Sat 10/3

6:00 am-5:55 pm

1 stop11h 55m

Santo Domingo Las Americas

Tue 10/6

3:35 pm-11:52 pm

1 stop8h 17m

$600
Quickest round-trip

PortlandSanto Domingo

PWM - SDQ

PWMSDQ

Portland

Thu 10/22

6:00 am-1:18 pm

1 stop7h 18m

Santo Domingo Las Americas

Tue 10/27

3:30 pm-11:43 pm

1 stop8h 13m

$600
Cheapest one-way

PortlandSanto Domingo

PWM - SDQ

PWMSDQ

Portland

Wed 9/9

6:00 am-7:55 pm

2 stops13h 55m

$179
Quickest one-way

PortlandSanto Domingo

PWM - SDQ

PWMSDQ

Portland

Wed 9/9

6:00 am-1:12 pm

1 stop7h 12m

$233

PortlandSanto Domingo

PWM - SDQ

PWMSDQ

Portland

Sun 6/14

6:25 am-6:04 pm

1 stop11h 39m

$277

PortlandSanto Domingo

PWM - SDQ

PWMSDQ

Portland

Sun 6/14

5:15 am-10:46 pm

2 stops41h 31m

$337

Flights are sorted by cheapest round-trip flights first.

Deals found on 5/18

Sorted by cheapest first
  • Most accurate provider: When it comes to deals on Portland, Maine-Santo Domingo flights, users find the pricing of FlightHub to be most consistent on Cheapflights vs. FlightHub Users can find the same prices on Portland, Maine-Santo Domingo flight deals on Cheapflights vs. FlightHub >95% of the time. Price accuracy is based on data collected from Portland, Maine-Santo Domingo flight searches over the past month and is updated monthly.
  • Most trusted provider: When it comes to deals on Portland, Maine-Santo Domingo flights, Cheapflights users trust FlightHub the most. FlightHub has received a user feedback score of 3 out of 3 stars (3 being the best), meaning they have been trusted the most by Cheapflights users looking for Portland, Maine-Santo Domingo flight deals. Provider user feedback score is based on Cheapflights searches over the past month and is updated monthly.

Best time to book a flight from Portland to Santo Domingo

Have a flexible travel schedule? Discover the best time to fly to Santo Domingo from Portland with our price prediction graph.
Estimated round-trip price
Rates are based on past data. Find the cheapest month and day to book your flight based on your travel requirements, then search for cheap deals.

Reviews of airlines servicing Santo Domingo

Get insights into the airlines that provide service to Santo Domingo. Read reviews, discover amenities, and learn about the overall travel experience offered by airlines. Use this information to make informed decisions when choosing an airline for your flight to Santo Domingo. Reviews last updated May 22, 2026.
See what other customers who have flown with United Airlines from Portland to Santo Domingo have to say. You can also see how each airline compares in terms of entertainment options, comfort, food, crew/service, and boarding process.
United Airlines
7.4
Good
9,751 reviews

Boarding

7.7

Crew

8.1

Overall

7.4

Entertainment

7.1

Comfort

7.3

Food

6.6

Reviews

1 / 20
4.0
Okay

Dynasty,May 2026

LAX - EWR

The food wasn’t nice - Hosts were not that kind.
United Airlines
7.4
Good
9,751 reviews
United Airlines
7.4
Good
9,751 reviews

Boarding

7.7

Crew

8.1

Overall

7.4

Entertainment

7.1

Comfort

7.3

Food

6.6

Reviews

1 / 20
4.0
Okay

Dynasty,May 2026

LAX - EWR

The food wasn’t nice - Hosts were not that kind.

Related info for your journey

Find useful and relevant information for your journey from Portland to Santo Domingo. Access travel guides, tips, and recommendations to enhance your travel experience. Get information about local attractions, weather, transportation options, and more.

  • How long is the flight from Portland, Maine to Santo Domingo?

    Airlines like Delta, American Airlines, and United Airlines fly from Portland, Maine to Santo Domingo in about 11h 36m. The time it takes to get you to your destination can typically vary by up to 6h 45m. The distance from Portland, Maine to Santo Domingo is about 1742 mi. This flight may include one or multiple stops.

  • What is the cheapest airline to fly from Portland, Maine to Santo Domingo round-trip?

    Cheapflights users have booked flights from Portland, Maine to Santo Domingo round-trip from $416.

  • Can I find deals for flights from Portland to Santo Domingo that include hotel bookings?

    Yes. In addition to deals on Portland to Santo Domingo flights, Cheapflights offers vacation packages that include both flights and hotel.

  • How can I find direct flights from Portland to Santo Domingo?

    After entering your origin and destination, apply the non-stop filter on the search result page to find direct flights from Portland to Santo Domingo.

  • Can I find deals for business class flights from Portland to Santo Domingo?

    Yes. Cheapflights offers flight deals from Portland to Santo Domingo by cabin class. In addition to browsing deals, you can also filter by cabin class on the search results page after making a search.

See more FAQs

Traveling to a place near Santo Domingo?

Book flights to Santo Domingo if you plan to visit one of these locations
Juan Dolio

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Top airline flying from Portland to Santo Domingo

Discover the top airline that operate flights from Portland to Santo Domingo. Compare their services, reliability, and customer satisfaction ratings to choose the airline that best suits your travel preferences and needs. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated May 22, 2026.
AirlineCheapestAverageFlexibilityOn-time
United AirlinesCheapest$416Average$683FlexibilityNo cancel feeOn-time69%

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