$181+ Cheap flights from Portland, ME (PWM) to Santo Domingo (SDQ)
This is the cheapest one-way flight price found by a Cheapflights user in the last 72 hours by searching for a flight departing on 6/1. Fares are subject to change and may not be available on all flights or dates of travel.
PWM — SDQ
Jun 9 — Jun 161
Round-trip
1 adult, Economy
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Find cheap flights from Portland to Santo Domingo with Cheapflights
1. Tell us where you want to go
Enter your travel information like dates, passengers, trip type (one-way or round trip), and preferred cabin class then click “Find deals”2. Select your favorite providers
We find the providers serving your travel needs. Choose up to four travel providers to compare side-by-side for flights, hotels, or car rentals.3. Compare prices and book
Review each provider’s pricing and select the best option for you! Book through your favorite provider’s website for a seamless experience.Cheap flight deals from Portland to Santo Domingo
Cheapest
Best
Last-minute
One-way
Cheapest flights from Portland to Santo DomingoExplore the most affordable flight options available from Portland to Santo Domingo. Find the lowest fares from popular airlines and budget airlines, with prices last updated on May 10, 2026.
Explore the most affordable flight options available from Portland to Santo Domingo. Find the lowest fares from popular airlines and budget airlines, with prices last updated on May 10, 2026.
This Delta deal was found by Cheapflights users on 5/8. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 5/222:38 pm
PWM
- SDQ
1 stop10h 03m
Delta
Mon 5/256:05 am
SDQ
- PWM
1 stop7h 53m
Delta
Deal found 5/8![Delta logo]()
$386
This American Airlines deal was found by Cheapflights users on 5/7. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 5/226:54 pm
PWM
- SDQ
1 stop17h 51m
American Airlines
Tue 5/261:45 pm
SDQ
- PWM
1 stop10h 06m
American Airlines
Deal found 5/7![American Airlines logo]()
$411
This American Airlines deal was found by Cheapflights users on 5/8. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 6/36:00 am
PWM
- SDQ
2 stops16h 55m
American Airlines
Mon 6/81:45 pm
SDQ
- PWM
1 stop8h 01m
American Airlines
Deal found 5/8![American Airlines logo]()
$465
This American Airlines deal was found by Cheapflights users on 5/8. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 5/226:00 am
PWM
- SDQ
2 stops16h 55m
American Airlines
Mon 5/251:45 pm
SDQ
- PWM
1 stop10h 06m
American Airlines
Deal found 5/8![American Airlines logo]()
$466
This United Airlines deal was found by Cheapflights users on 5/7. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 10/266:00 am
PWM
- SDQ
1 stop6h 41m
United Airlines
Thu 10/295:00 am
SDQ
- PWM
1 stop8h 38m
United Airlines
Deal found 5/7![United Airlines logo]()
$506
This Faresmojo deal was found by Cheapflights users on 5/6. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Faresmojo is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 6/266:00 am
PWM
- SDQ
1 stop7h 16m
JetBlue
Thu 7/26:06 am
SDQ
- PWM
1 stop8h 13m
JetBlue
Deal found 5/6![JetBlue logo]()
$527
Best flights from Portland to Santo DomingoDiscover carefully curated flight deals from Portland to Santo Domingo that have cost, travel time, and layovers in mind to ensure you get the best travel experience. Data last updated May 10, 2026.
Discover carefully curated flight deals from Portland to Santo Domingo that have cost, travel time, and layovers in mind to ensure you get the best travel experience. Data last updated May 10, 2026.
This Delta deal was found by Cheapflights users on 5/8. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 5/222:38 pm
PWM
- SDQ
1 stop10h 03m
Delta
Mon 5/256:05 am
SDQ
- PWM
1 stop7h 53m
Delta
Deal found 5/8![Delta logo]()
$386
This United Airlines deal was found by Cheapflights users on 5/8. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 10/266:00 am
PWM
- SDQ
1 stop6h 41m
United Airlines
Thu 10/291:53 pm
SDQ
- PWM
1 stop9h 04m
United Airlines
Deal found 5/8![United Airlines logo]()
$506
This American Airlines deal was found by Cheapflights users on 5/9. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 6/2611:02 am
PWM
- SDQ
2 stops11h 53m
American Airlines
Thu 7/21:57 pm
SDQ
- PWM
1 stop8h 36m
American Airlines
Deal found 5/9![American Airlines logo]()
$718
This Delta deal was found by Cheapflights users on 5/8. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 6/32:38 pm
PWM
- SDQ
1 stop10h 03m
Delta
Mon 6/86:06 am
SDQ
- PWM
1 stop8h 13m
Delta
Deal found 5/8![Delta logo]()
$420
This Delta deal was found by Cheapflights users on 5/7. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 6/272:59 pm
PWM
- SDQ
1 stop9h 43m
Delta
Sun 7/52:05 pm
SDQ
- PWM
1 stop10h 47m
Delta
Deal found 5/7![Delta logo]()
$684
Last-minute flights from Portland to Santo DomingoDiscover last-minute flight deals from Portland to Santo Domingo. Data last updated May 10, 2026 and is based on user searches.
Discover last-minute flight deals from Portland to Santo Domingo. Data last updated May 10, 2026 and is based on user searches.
This Delta deal was found by Cheapflights users on 5/8. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 5/222:38 pm
PWM
- SDQ
1 stop10h 03m
Delta
Mon 5/256:05 am
SDQ
- PWM
1 stop7h 53m
Delta
Deal found 5/8![Delta logo]()
$386
This American Airlines deal was found by Cheapflights users on 5/7. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 5/226:54 pm
PWM
- SDQ
1 stop17h 51m
American Airlines
Tue 5/261:45 pm
SDQ
- PWM
1 stop10h 06m
American Airlines
Deal found 5/7![American Airlines logo]()
$411
This American Airlines deal was found by Cheapflights users on 5/8. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 5/226:00 am
PWM
- SDQ
2 stops16h 55m
American Airlines
Mon 5/251:45 pm
SDQ
- PWM
1 stop10h 06m
American Airlines
Deal found 5/8![American Airlines logo]()
$466
This American Airlines deal was found by Cheapflights users on 5/8. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 6/36:00 am
PWM
- SDQ
2 stops16h 55m
American Airlines
Mon 6/81:45 pm
SDQ
- PWM
1 stop8h 01m
American Airlines
Deal found 5/8![American Airlines logo]()
$465
This Faresmojo deal was found by Cheapflights users on 5/6. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Faresmojo is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 6/266:00 am
PWM
- SDQ
1 stop7h 16m
JetBlue
Thu 7/26:06 am
SDQ
- PWM
1 stop8h 13m
JetBlue
Deal found 5/6![JetBlue logo]()
$527
This American Airlines deal was found by Cheapflights users on 5/7. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 6/275:26 am
PWM
- SDQ
2 stops17h 29m
American Airlines
Sun 7/51:57 pm
SDQ
- PWM
1 stop8h 36m
American Airlines
Deal found 5/7![American Airlines logo]()
$571
One-way flights from Portland to Santo DomingoSearch for one-way flight options from Portland to Santo Domingo. Find affordable one-way fares based on user searches. Data last updated May 10, 2026.
Search for one-way flight options from Portland to Santo Domingo. Find affordable one-way fares based on user searches. Data last updated May 10, 2026.
This Delta deal was found by Cheapflights users on 5/6. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 6/12:38 pm
PWM
- SDQ
1 stop10h 03m
Delta
Deal found 5/6![Delta logo]()
$181
This American Airlines deal was found by Cheapflights users on 5/6. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 6/16:00 am
PWM
- SDQ
2 stops16h 55m
American Airlines
Deal found 5/6![American Airlines logo]()
$187
This American Airlines deal was found by Cheapflights users on 5/7. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 5/226:54 pm
PWM
- SDQ
1 stop17h 51m
American Airlines
Deal found 5/7![American Airlines logo]()
$206
This Delta deal was found by Cheapflights users on 5/9. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 5/222:38 pm
PWM
- SDQ
1 stop10h 03m
Delta
Deal found 5/9![Delta logo]()
$215
This United Airlines deal was found by Cheapflights users on 5/8. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 10/156:00 am
PWM
- SDQ
1 stop8h 10m
United Airlines
Deal found 5/8![United Airlines logo]()
$225
This United Airlines deal was found by Cheapflights users on 5/7. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 5/227:16 pm
PWM
- SDQ
2 stops27h 30m
United Airlines
Deal found 5/7![United Airlines logo]()
$343
This Kiwi.com deal was found by Cheapflights users on 5/6. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 6/19:52 am
PWM
- SDQ
3 stops35h 53m
Multiple Airlines
Deal found 5/6![Multiple Airlines logo]()
$403
This United Airlines deal was found by Cheapflights users on 5/6. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 6/15:15 am
PWM
- SDQ
3 stops41h 31m
United Airlines
Deal found 5/6![United Airlines logo]()
$423
This Kiwi.com deal was found by Cheapflights users on 5/7. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 5/226:13 pm
PWM
- SDQ
3 stops43h 26m
Multiple Airlines
Deal found 5/7![Multiple Airlines logo]()
$456
Find flight deals from Portland to Santo Domingo
Discover tips and strategies to find the most affordable flight options for your journey from Portland (PWM) to Santo Domingo (SDQ). Learn about various techniques such as flexible date searches, comparing prices across and setting up price alerts. Use these methods to find the cheapest flights available for your travel needs. Data last updated May 10, 2026.
Most accurate provider | FlightHub 3 stars |
|---|---|
Most trusted provider | FlightHub 3 stars |
Round-trip from | $386 (Delta) |
One-way from | $181 (Delta) |
Cheapflights Fare Finder
Customize your flight search to find flights from Portland to Santo Domingo that fit within your specific budget. Explore options based on user searches and filter the results based on your desired price range. Find flights that match your budget for a cost-effective journey. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated May 10, 2026.
Use the filters below to find and compare flights from Portland to Santo Domingo that are best for you.
Fly from
Fly to
Route
Depart
Return
Cheapest round-trip
PortlandSanto Domingo
PWM - SDQ
PWMSDQ
Portland
Fri 5/22
2:38 pm-12:41 am
1 stop10h 03m
Santo Domingo Las Americas
Mon 5/25
6:05 am-1:58 pm
1 stop7h 53m
$386
PortlandSanto Domingo
PWM - SDQ
PWMSDQ
Portland
Wed 6/3
2:38 pm-12:41 am
1 stop10h 03m
Santo Domingo Las Americas
Mon 6/8
6:06 am-2:19 pm
1 stop8h 13m
$420
Quickest round-trip
PortlandSanto Domingo
PWM - SDQ
PWMSDQ
Portland
Mon 10/26
6:00 am-12:41 pm
1 stop6h 41m
Santo Domingo Las Americas
Thu 10/29
1:53 pm-10:57 pm
1 stop9h 04m
$506
PortlandSanto Domingo
PWM - SDQ
PWMSDQ
Portland
Sat 6/27
2:59 pm-12:42 am
1 stop9h 43m
Santo Domingo Las Americas
Sun 7/5
2:05 pm-12:52 am
1 stop10h 47m
$684
PortlandSanto Domingo
PWM - SDQ
PWMSDQ
Portland
Fri 6/26
11:02 am-10:55 pm
2 stops11h 53m
Santo Domingo Las Americas
Thu 7/2
1:57 pm-10:33 pm
1 stop8h 36m
$718
Cheapest one-way
Quickest one-way
PortlandSanto Domingo
PWM - SDQ
PWMSDQ
Portland
Mon 6/1
2:38 pm-12:41 am
1 stop10h 03m
$181
PortlandSanto Domingo
PWM - SDQ
PWMSDQ
Portland
Mon 6/1
6:54 pm-12:45 pm
1 stop17h 51m
$181
PortlandSanto Domingo
PWM - SDQ
PWMSDQ
Portland
Fri 5/22
2:38 pm-12:41 am
1 stop10h 03m
$181
PortlandSanto Domingo
PWM - SDQ
PWMSDQ
Portland
Fri 5/22
6:54 pm-12:45 pm
1 stop17h 51m
$206
PortlandSanto Domingo
PWM - SDQ
PWMSDQ
Portland
Fri 5/22
7:16 pm-10:46 pm
2 stops27h 30m
$343
Showing 1-10 of 12 resultsSorted by cheapest first
- Most accurate provider: When it comes to deals on Portland, Maine-Santo Domingo flights, users find the pricing of FlightHub to be most consistent on Cheapflights vs. FlightHub Users can find the same prices on Portland, Maine-Santo Domingo flight deals on Cheapflights vs. FlightHub >95% of the time. Price accuracy is based on data collected from Portland, Maine-Santo Domingo flight searches over the past month and is updated monthly.
- Most trusted provider: When it comes to deals on Portland, Maine-Santo Domingo flights, Cheapflights users trust FlightHub the most. FlightHub has received a user feedback score of 3 out of 3 stars (3 being the best), meaning they have been trusted the most by Cheapflights users looking for Portland, Maine-Santo Domingo flight deals. Provider user feedback score is based on Cheapflights searches over the past month and is updated monthly.
Best time to book a flight from Portland to Santo Domingo
Have a flexible travel schedule? Discover the best time to fly to Santo Domingo from Portland with our price prediction graph.
PWM-SDQ
Estimated round-trip price
Rates are based on past data. Find the cheapest month and day to book your flight based on your travel requirements, then search for cheap deals.
Reviews of airlines servicing Santo Domingo
Get insights into the airlines that provide service to Santo Domingo. Read reviews, discover amenities, and learn about the overall travel experience offered by airlines. Use this information to make informed decisions when choosing an airline for your flight to Santo Domingo. Reviews last updated May 10, 2026.
See what other customers who have flown with United Airlines from Portland to Santo Domingo have to say. You can also see how each airline compares in terms of entertainment options, comfort, food, crew/service, and boarding process.
Food
6.6
Crew
8.1
Boarding
7.7
Comfort
7.3
Overall
7.4
Entertainment
7.1
Reviews
1 / 20
8.0
ExcellentAnonymous,Apr 2026
DFW - EWR
Food
6.6
Crew
8.1
Boarding
7.7
Comfort
7.3
Overall
7.4
Entertainment
7.1
Reviews
1 / 20
8.0
ExcellentAnonymous,Apr 2026
DFW - EWR
Related info for your journey
Find useful and relevant information for your journey from Portland to Santo Domingo. Access travel guides, tips, and recommendations to enhance your travel experience. Get information about local attractions, weather, transportation options, and more.
Traveling to a place near Santo Domingo?
Book flights to Santo Domingo if you plan to visit one of these locationsJuan Dolio
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Complete your trip
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Portland and Santo Domingo flights
Browse other Portland and Santo Domingo flight options. Last updated on May 10, 2026.
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Browse through other flights departing from Portland. Flights are based on user searches made on Cheapflights and were last updated on May 10, 2026.
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Explore flights to Santo Domingo departing from other origins. Flights are based on user searches made on Cheapflights and were last updated on May 10, 2026.
Top airline flying from Portland to Santo Domingo
Discover the top airline that operate flights from Portland to Santo Domingo. Compare their services, reliability, and customer satisfaction ratings to choose the airline that best suits your travel preferences and needs. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated May 10, 2026.
| Airline | Cheapest | Average | Flexibility | On-time |
|---|---|---|---|---|
| Cheapest$416 | Average$683 | FlexibilityNo cancel fee | On-time69% |