$494+ Cheap flights from Portland, ME (PWM) to Santo Domingo (SDQ)
This is the cheapest round-trip flight price found by a Cheapflights user in the last 72 hours by searching for a flight departing on 10/26. Fares are subject to change and may not be available on all flights or dates of travel.
PWM — SDQ
Nov 11 — Nov 181
Round-trip
1 adult, Economy
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1. Tell us where you want to go
Enter your travel information like dates, passengers, trip type (one-way or round trip), and preferred cabin class then click “Find deals”2. Select your favorite providers
We find the providers serving your travel needs. Choose up to four travel providers to compare side-by-side for flights, hotels, or car rentals.3. Compare prices and book
Review each provider’s pricing and select the best option for you! Book through your favorite provider’s website for a seamless experience.Cheap flight deals from Portland to Santo Domingo
Cheapest
Best
Last-minute
Cheapest flights from Portland to Santo DomingoExplore the most affordable flight options available from Portland to Santo Domingo. Find the lowest fares from popular airlines and budget airlines, with prices last updated on October 12, 2026.
Explore the most affordable flight options available from Portland to Santo Domingo. Find the lowest fares from popular airlines and budget airlines, with prices last updated on October 12, 2026.
This United Airlines deal was found by Cheapflights users on 10/9. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 10/265:50 am -
1 stop6h 51m
Fri 10/305:00 am -
2 stops18h 59m
Deal found 10/9![United Airlines logo]()
$494
This American Airlines deal was found by Cheapflights users on 10/12. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 12/296:42 pm -
2 stops19h 35m
Thu 1/74:17 pm -
2 stops20h 02m
Deal found 10/12![American Airlines logo]()
$932
This American Airlines deal was found by Cheapflights users on 10/7. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 11/206:47 pm -
2 stops18h 56m
Sun 11/296:00 am -
2 stops17h 52m
Deal found 10/7![American Airlines logo]()
$1,042
This United Airlines deal was found by Cheapflights users on 10/7. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 11/205:50 am -
1 stop8h 16m
Sun 11/296:00 am -
2 stops33h 27m
Deal found 10/7![United Airlines logo]()
$1,120
This United Airlines deal was found by Cheapflights users on 10/12. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 12/296:00 am -
1 stop16h 46m
Thu 1/74:18 pm -
1 stop8h 14m
Deal found 10/12![United Airlines logo]()
$1,711
Best flights from Portland to Santo DomingoDiscover carefully curated flight deals from Portland to Santo Domingo that have cost, travel time, and layovers in mind to ensure you get the best travel experience. Data last updated October 12, 2026.
Discover carefully curated flight deals from Portland to Santo Domingo that have cost, travel time, and layovers in mind to ensure you get the best travel experience. Data last updated October 12, 2026.
This United Airlines deal was found by Cheapflights users on 10/9. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 10/265:08 pm -
2 stops19h 33m
Fri 10/305:00 am -
2 stops29h 07m
Deal found 10/9![United Airlines logo]()
$494
Last-minute flights from Portland to Santo DomingoDiscover last-minute flight deals from Portland to Santo Domingo. Data last updated October 12, 2026 and is based on user searches.
Discover last-minute flight deals from Portland to Santo Domingo. Data last updated October 12, 2026 and is based on user searches.
This United Airlines deal was found by Cheapflights users on 10/9. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 10/265:50 am -
1 stop6h 51m
Fri 10/305:00 am -
2 stops18h 59m
Deal found 10/9![United Airlines logo]()
$494
This American Airlines deal was found by Cheapflights users on 10/7. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 11/206:47 pm -
2 stops18h 56m
Sun 11/296:00 am -
2 stops17h 52m
Deal found 10/7![American Airlines logo]()
$1,042
This United Airlines deal was found by Cheapflights users on 10/7. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 11/205:50 am -
1 stop8h 16m
Sun 11/296:00 am -
2 stops33h 27m
Deal found 10/7![United Airlines logo]()
$1,120
Find flight deals from Portland to Santo Domingo
Discover tips and strategies to find the most affordable flight options for your journey from Portland (PWM) to Santo Domingo (SDQ). Learn about various techniques such as flexible date searches, comparing prices across and setting up price alerts. Use these methods to find the cheapest flights available for your travel needs. Data last updated October 12, 2026.
Round-trip from | $494 (United Airlines) |
|---|
Cheapflights Fare Finder
Customize your flight search to find flights from Portland to Santo Domingo that fit within your specific budget. Explore options based on user searches and filter the results based on your desired price range. Find flights that match your budget for a cost-effective journey. Over the last 7 days, Cheapflights users made 7,457,451 searches. Data last updated October 12, 2026.
Use the filters below to find and compare flights from Portland to Santo Domingo that are best for you.
Fly from
Fly to
Route
Depart
Return
Cheapest round-trip
Quickest round-trip
PortlandSanto Domingo
PWM Portland - SDQ Santo Domingo Las Americas
PWMSDQ
Portland
Mon 10/26
5:08 pm-12:41 pm
2 stops19h 33m
Santo Domingo Las Americas
Fri 10/30
5:00 am-10:07 am
2 stops29h 07m
$494
Sorted by cheapest first
Best time to book a flight from Portland to Santo Domingo
Have a flexible travel schedule? Discover the best time to fly to Santo Domingo from Portland with our price prediction graph.
PWM-SDQ
Estimated round-trip price
Rates are based on past data. Find the cheapest month and day to book your flight based on your travel requirements, then search for cheap deals.
Reviews of airlines servicing Santo Domingo
Get insights into the airlines that provide service to Santo Domingo. Read reviews, discover amenities, and learn about the overall travel experience offered by airlines. Use this information to make informed decisions when choosing an airline for your flight to Santo Domingo. Reviews last updated October 12, 2026.
See what other customers who have flown with United Airlines from Portland to Santo Domingo have to say. You can also see how each airline compares in terms of entertainment options, comfort, food, crew/service, and boarding process.
Comfort
7.3
Entertainment
7.1
Crew
8.1
Food
6.7
Overall
7.4
Boarding
7.7
Reviews
1 / 20
8.0
ExcellentAsha,Sep 2026
LGA - IAH
Comfort
7.3
Entertainment
7.1
Crew
8.1
Food
6.7
Overall
7.4
Boarding
7.7
Reviews
1 / 20
8.0
ExcellentAsha,Sep 2026
LGA - IAH
Related info for your journey
Find useful and relevant information for your journey from Portland to Santo Domingo. Access travel guides, tips, and recommendations to enhance your travel experience. Get information about local attractions, weather, transportation options, and more.
Traveling to a place near Santo Domingo?
Book flights to Santo Domingo if you plan to visit one of these locationsJuan Dolio
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Portland and Santo Domingo flights
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Top airline flying from Portland to Santo Domingo
Discover the top airline that operate flights from Portland to Santo Domingo. Compare their services, reliability, and customer satisfaction ratings to choose the airline that best suits your travel preferences and needs. Over the last 7 days, Cheapflights users made 7,457,451 searches. Data last updated October 12, 2026.
| Airline | Cheapest | Average | Flexibility | On-time |
|---|---|---|---|---|
| Cheapest$416 | Average$707 | FlexibilityNo cancel fee | On-time69% |