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$228+ Cheap flights from Panama to Louisville (SDF)

This is the cheapest one-way flight price found by a Cheapflights user in the last 72 hours by searching for a flight departing on 8/24. Fares are subject to change and may not be available on all flights or dates of travel.
PTY — SDF
Aug 23 — Aug 301
Sat 8/23
Sat 8/30
1 adult, Economy
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Cheap flight deals from Panama to Louisville

Keep the following information in mind while searching for Panama to Louisville flight deals. Data was last updated August 18, 2025.

Round-trip from

$405
(Avianca Connect)

One-way from

$228
(Avianca Connect)

Popular in

January

Cheapest in

February

Average price

$500
From Panama to Louisville Intl
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One-way flight from Panama to Louisville Intl
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Highest demand for flights based on searches. 15% potential increase in price ($107 potential increase over avg. RT price).
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Cheapest flight prices on average. 8% potential price decrease ($45 potential savings vs. average RT price).
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Average for round-trip flights in August 2025
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Find flight deals from Panama to Louisville

Cheapest flights from Panama to Louisville
Explore the most affordable flight options available from Panama to Louisville. Find the lowest fares from popular airlines and budget airlines, with prices last updated on August 18, 2025.

This Avianca Connect deal was found by Cheapflights users on 8/17. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Avianca Connect is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 9/123:25 amPTY - SDF
2 stops17h 39mMultiple Airlines
Sun 9/288:23 amSDF - PTY
2 stops13h 47mMultiple Airlines
Deal found 8/17$405
This American Airlines deal was found by Cheapflights users on 8/17. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 10/203:15 pmPTY - SDF
1 stop8h 21mAmerican Airlines
Sun 11/27:31 pmSDF - PTY
2 stops18h 05mAmerican Airlines
Deal found 8/17$463
This Delta deal was found by Cheapflights users on 8/17. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 10/22:10 pmPTY - SDF
1 stop8h 42mDelta
Tue 10/287:09 amSDF - PTY
1 stop6h 47mDelta
Deal found 8/17$498
This American Airlines deal was found by Cheapflights users on 8/17. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 10/23:31 pmPTY - SDF
2 stops22h 05mAmerican Airlines
Tue 10/286:48 pmSDF - PTY
2 stops20h 15mAmerican Airlines
Deal found 8/17$512
This Avianca Connect deal was found by Cheapflights users on 8/17. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Avianca Connect is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 9/113:20 amPTY - SDF
2 stops17h 44mMultiple Airlines
Sun 9/288:23 amSDF - PTY
2 stops13h 47mMultiple Airlines
Deal found 8/17$524
This Delta deal was found by Cheapflights users on 8/17. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 9/122:10 pmPTY - SDF
1 stop7h 41mDelta
Sun 9/287:10 amSDF - PTY
1 stop6h 45mDelta
Deal found 8/17$543
This United Airlines deal was found by Cheapflights users on 8/16. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 9/153:30 pmPTY - SDF
2 stops17h 32mUnited Airlines
Mon 9/227:36 pmSDF - PTY
2 stops24h 01mUnited Airlines
Deal found 8/16$547
This United Airlines deal was found by Cheapflights users on 8/17. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 9/83:30 pmPTY - SDF
2 stops20h 47mUnited Airlines
Tue 9/239:05 amSDF - PTY
2 stops10h 32mUnited Airlines
Deal found 8/17$569
This Mytrip deal was found by Cheapflights users on 8/17. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Mytrip is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 8/218:10 pmPTY - SDF
3 stops21h 43mMultiple Airlines
Sat 8/237:58 pmSDF - PTY
3 stops29h 12mMultiple Airlines
Deal found 8/17$581
This United Airlines deal was found by Cheapflights users on 8/17. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 9/123:30 pmPTY - SDF
2 stops17h 30mUnited Airlines
Sun 9/287:20 pmSDF - PTY
2 stops19h 54mUnited Airlines
Deal found 8/17$590

Cheapflights Fare Finder

 
Customize your flight search to find flights from Panama to Louisville that fit within your specific budget. Explore options based on user searches and filter the results based on your desired price range. Find flights that match your budget for a cost-effective journey. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated August 18, 2025.
Use the filters below to find and compare flights from Panama to Louisville that are best for you.

Fly from

Panama

Fly to

Louisville

Route

Depart

Return

Price

Panama CityLouisville

PTY - SDF

PTYSDF

Panama City Tocumen Intl

Sun 9/14

3:20 am-10:04 pm

2 stops17h 44m

Louisville Intl

Mon 9/22

8:23 am-12:45 am

2 stops17h 22m

$405

Panama CityLouisville

PTY - SDF

PTYSDF

Panama City Tocumen Intl

Fri 9/12

3:25 am-10:04 pm

2 stops17h 39m

Louisville Intl

Sun 9/28

8:23 am-9:10 pm

2 stops13h 47m

$405

Panama CityLouisville

PTY - SDF

PTYSDF

Panama City Tocumen Intl

Mon 10/20

3:15 pm-12:36 am

1 stop8h 21m

Louisville Intl

Sun 11/2

7:31 pm-1:36 pm

2 stops18h 05m

$463

Panama CityLouisville

PTY - SDF

PTYSDF

Panama City Tocumen Intl

Thu 10/2

2:10 pm-10:46 pm

1 stop7h 36m

Louisville Intl

Tue 10/28

6:00 am-12:56 pm

1 stop7h 56m

$498

Panama CityLouisville

PTY - SDF

PTYSDF

Panama City Tocumen Intl

Thu 10/2

3:31 pm-12:20 pm

2 stops19h 49m

Louisville Intl

Tue 10/28

7:02 pm-2:03 pm

2 stops20h 01m

$512

Panama CityLouisville

PTY - SDF

PTYSDF

Panama City Tocumen Intl

Sun 8/24

3:20 am-6:53 pm

2 stops14h 33m

$228

Panama CityLouisville

PTY - SDF

PTYSDF

Panama City Tocumen Intl

Mon 8/25

3:30 pm-1:30 pm

1 stop21h 00m

$351

Flights are sorted by cheapest round-trip flights first.

Deals found on 8/16

Best time to book a flight from Panama to Louisville

Have a flexible travel schedule? Discover the best time to fly to Louisville from Panama with our price prediction graph.
Estimated round-trip price
Rates are based on past data. Find the cheapest month and day to book your flight based on your travel requirements, then search for cheap deals.

Cheapflights Insights

Everything you need to know about your flight from Panama to Louisville

What is the cheapest month to book a flight from Panama to Louisville?

Currently, January is the cheapest month in which you can book a flight from Panama to Louisville (average of $299). Flying from Panama to Louisville in April is currently the most expensive (average of $369). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.

What is the cheapest time of day to fly from PA to SDF?

Find hourly flight availability from Panama to Louisville. Discover flight options and departure times throughout the day, allowing you to choose a departure time that suits your schedule. Data last updated August 18, 2025.

Regardless of the time of day you decide to fly, the ticket price will remain around the same. Book flights from Panama to Louisville as you normally would.

Reviews of airlines servicing Louisville

Get insights into the airlines that provide service to Louisville. Read reviews, discover amenities, and learn about the overall travel experience offered by airlines. Use this information to make informed decisions when choosing an airline for your flight to Louisville. Reviews last updated August 18, 2025.
Peruse reviews from past customers who have flown with Delta, United Airlines, and American Airlines from Panama to Louisville to help guide your decision. You can also see how each airline stacks up in terms of entertainment options, comfort, food, crew/service, and boarding process.
Delta
8.0
Very good
7,981 reviews

Entertainment

7.9

Food

7.3

Crew

8.5

Boarding

8.2

Overall

8.0

Comfort

7.9

Reviews

1 / 20
6.0
Good

Morgan Rae,Aug 2025

BRU - JFK

Typically I choose delta because they do a great job but this time the flight attendant in my zone was very rude and didnt offer the same treatment as she did to others
Delta
8.0
Very good
7,981 reviews
Delta
8.0
Very good
7,981 reviews

Entertainment

7.9

Food

7.3

Crew

8.5

Boarding

8.2

Overall

8.0

Comfort

7.9

Reviews

1 / 20
6.0
Good

Morgan Rae,Aug 2025

BRU - JFK

Typically I choose delta because they do a great job but this time the flight attendant in my zone was very rude and didnt offer the same treatment as she did to others
United Airlines
7.4
Good
8,925 reviews
Delta
8.0
Very good
7,981 reviews

Entertainment

7.9

Food

7.3

Crew

8.5

Boarding

8.2

Overall

8.0

Comfort

7.9

Reviews

1 / 20
6.0
Good

Morgan Rae,Aug 2025

BRU - JFK

Typically I choose delta because they do a great job but this time the flight attendant in my zone was very rude and didnt offer the same treatment as she did to others
American Airlines
7.2
Good
10,000 reviews
Delta
8.0
Very good
7,981 reviews

Entertainment

7.9

Food

7.3

Crew

8.5

Boarding

8.2

Overall

8.0

Comfort

7.9

Reviews

1 / 20
6.0
Good

Morgan Rae,Aug 2025

BRU - JFK

Typically I choose delta because they do a great job but this time the flight attendant in my zone was very rude and didnt offer the same treatment as she did to others

Related info for your journey

Find useful and relevant information for your journey from Panama to Louisville. Access travel guides, tips, and recommendations to enhance your travel experience. Get information about local attractions, weather, transportation options, and more.

  • What airport do you fly into for flights to Louisville from Panama?

    Located just 5.3 mi from the city center, Louisville Intl (SDF) is the airport most travelers will use when flying to Louisville from Panama.

  • Can I find deals for flights from Panama to Louisville that include hotel bookings?

    Yes. In addition to deals on Panama to Louisville flights, Cheapflights offers vacation packages that include both flights and hotel.

  • How can I find direct flights from Panama to Louisville?

    After entering your origin and destination, apply the non-stop filter on the search result page to find direct flights from Panama to Louisville.

  • Can I find deals for business class flights from Panama to Louisville?

    Yes. Cheapflights offers flight deals from Panama to Louisville by cabin class. In addition to browsing deals, you can also filter by cabin class on the search results page after making a search.

  • What is the cheapest month to book a flight from Panama to Louisville?

    Currently, January is the cheapest month in which you can book a flight from Panama to Louisville (average of $299). Flying from Panama to Louisville in April is currently the most expensive (average of $369). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.

See more FAQs

Traveling to a place near Louisville?

Book flights to Louisville if you plan to visit one of these locations
Shepherdsville
Jeffersonville
Elizabethtown
Corydon
Bardstown

Browse thousands of different options on Cheapflights for your next trip

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Alternative routes for Panama to Louisville

See prices for flight routes from nearby airports that may be better suited for you.
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Top 3 airlines flying from Panama to Louisville

Discover the top 3 airlines that operate flights from Panama to Louisville. Compare their services, reliability, and customer satisfaction ratings to choose the airline that best suits your travel preferences and needs. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated August 18, 2025.
AirlineCheapestAverageFlexibilityOn-time
DeltaCheapest$338Average$504FlexibilityNo cancel feeOn-timeN/A
United AirlinesCheapest$366Average$557FlexibilityNo cancel feeOn-time69%
American AirlinesCheapest$370Average$627FlexibilityNo cancel feeOn-time71%

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