HomeSearch by dateVacation packagesHotelsFlight dealsCar rentalTravel tips & news
Louisville

$269+ Cheap flights from Panama to Louisville (SDF)

This is the cheapest one-way flight price found by a Cheapflights user in the last 72 hours by searching for a flight departing on 4/7. Fares are subject to change and may not be available on all flights or dates of travel.
PTY — SDF
Feb 28 — Mar 71
Sat 2/28
Sat 3/7
1 adult, Economy
We work with more than 300 partners to bring you better travel deals

Find cheap flights from Panama to Louisville with Cheapflights

1. Tell us where you want to go

Enter your travel information like dates, passengers, trip type (one-way or round trip), and preferred cabin class then click “Find deals”

2. Select your favorite providers

We find the providers serving your travel needs. Choose up to four travel providers to compare side-by-side for flights, hotels, or car rentals.

3. Compare prices and book

Review each provider’s pricing and select the best option for you! Book through your favorite provider’s website for a seamless experience.

Cheap flight deals from Panama to Louisville

Cheapest flights from Panama to Louisville
Explore the most affordable flight options available from Panama to Louisville. Find the lowest fares from popular airlines and budget airlines, with prices last updated on January 29, 2026.

This United Airlines deal was found by Cheapflights users on 1/27. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 5/13:30 pm
PTY
-
SDF
2 stops17h 11m
United Airlines
Mon 5/116:00 am
SDF
-
PTY
1 stop13h 37m
United Airlines
Deal found 1/27$472
This United Airlines deal was found by Cheapflights users on 1/27. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 2/274:41 pm
PTY
-
SDF
2 stops20h 42m
United Airlines
Wed 3/257:05 am
SDF
-
PTY
2 stops12h 33m
United Airlines
Deal found 1/27$474
This United Airlines deal was found by Cheapflights users on 1/28. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 5/267:55 am
PTY
-
SDF
1 stop13h 20m
United Airlines
Thu 5/286:14 am
SDF
-
PTY
1 stop10h 58m
United Airlines
Deal found 1/28$481
This United Airlines deal was found by Cheapflights users on 1/27. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 5/169:45 am
PTY
-
SDF
1 stop11h 37m
United Airlines
Sun 5/245:45 am
SDF
-
PTY
2 stops13h 52m
United Airlines
Deal found 1/27$485
This American Airlines deal was found by Cheapflights users on 1/27. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 5/211:10 pm
PTY
-
SDF
2 stops23h 47m
American Airlines
Mon 5/258:15 pm
SDF
-
PTY
2 stops16h 55m
American Airlines
Deal found 1/27$498
This United Airlines deal was found by Cheapflights users on 1/27. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 5/43:30 pm
PTY
-
SDF
2 stops24h 31m
United Airlines
Sun 5/107:20 pm
SDF
-
PTY
2 stops19h 54m
United Airlines
Deal found 1/27$500
This United Airlines deal was found by Cheapflights users on 1/27. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 2/244:41 pm
PTY
-
SDF
2 stops20h 42m
United Airlines
Wed 3/257:05 am
SDF
-
PTY
2 stops12h 33m
United Airlines
Deal found 1/27$521
This United Airlines deal was found by Cheapflights users on 1/28. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 2/254:41 pm
PTY
-
SDF
2 stops20h 42m
United Airlines
Wed 3/187:05 am
SDF
-
PTY
2 stops12h 33m
United Airlines
Deal found 1/28$570
This United Airlines deal was found by Cheapflights users on 1/27. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 5/2110:00 am
PTY
-
SDF
1 stop10h 30m
United Airlines
Mon 5/257:05 am
SDF
-
PTY
1 stop10h 07m
United Airlines
Deal found 1/27$581
This American Airlines deal was found by Cheapflights users on 1/28. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 3/81:40 pm
PTY
-
SDF
2 stops18h 10m
American Airlines
Thu 3/126:12 pm
SDF
-
PTY
2 stops19h 28m
American Airlines
Deal found 1/28$586
This American Airlines deal was found by Cheapflights users on 1/27. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 2/272:40 pm
PTY
-
SDF
2 stops20h 02m
American Airlines
Thu 3/267:57 pm
SDF
-
PTY
2 stops19h 23m
American Airlines
Deal found 1/27$588

Find flight deals from Panama to Louisville

Keep the following information in mind while searching for Panama to Louisville flight deals. Data was last updated January 29, 2026.

Most accurate provider

FlightHub
3 stars

Most trusted provider

FlightHub
3 stars

Round-trip from

$472
(United Airlines)

One-way from

$269
(United Airlines)

Popular in

December

Cheapest in

November

Average price

$627
Provider with most accurate pricing for Panama City Tocumen Intl-Louisville Intl flight deals.
Search Deals
Provider most trusted by Cheapflights users for Panama City Tocumen Intl-Louisville Intl flights.
Search Deals
From Panama to Louisville Intl
Search Deals
One-way flight from Panama to Louisville Intl
Search Deals
Highest demand for flights based on searches. 9% potential increase in price ($54 potential increase over avg. RT price).
Search Deals
Cheapest flight prices on average. 3% potential price decrease ($18 potential savings vs. average RT price).
Search Deals
Average for round-trip flights in January 2026
Search Deals

Cheapflights Fare Finder

 
Customize your flight search to find flights from Panama to Louisville that fit within your specific budget. Explore options based on user searches and filter the results based on your desired price range. Find flights that match your budget for a cost-effective journey. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated January 29, 2026.
Use the filters below to find and compare flights from Panama to Louisville that are best for you.

Fly from

Panama

Fly to

Louisville

Route

Depart

Return

Price

Panama CityLouisville

PTY - SDF

PTYSDF

Panama City Tocumen Intl

Thu 4/23

2:27 pm-10:50 pm

1 stop7h 23m

Louisville Intl

Sun 4/26

7:05 am-1:02 pm

1 stop6h 57m

$472

Panama CityLouisville

PTY - SDF

PTYSDF

Panama City Tocumen Intl

Fri 5/1

10:55 pm-1:22 pm

2 stops13h 27m

Louisville Intl

Mon 5/11

7:20 pm-2:14 pm

2 stops19h 54m

$472

Panama CityLouisville

PTY - SDF

PTYSDF

Panama City Tocumen Intl

Thu 4/23

2:27 pm-10:50 pm

1 stop7h 23m

Louisville Intl

Mon 4/27

7:05 am-1:02 pm

1 stop6h 57m

$472

Panama CityLouisville

PTY - SDF

PTYSDF

Panama City Tocumen Intl

Fri 4/24

7:55 am-9:59 pm

1 stop13h 04m

Louisville Intl

Mon 4/27

6:00 am-4:12 pm

1 stop11h 12m

$472

Panama CityLouisville

PTY - SDF

PTYSDF

Panama City Tocumen Intl

Thu 4/23

3:30 pm-9:59 pm

1 stop29h 29m

Louisville Intl

Mon 4/27

5:43 pm-2:14 pm

2 stops21h 31m

$472

Panama CityLouisville

PTY - SDF

PTYSDF

Panama City Tocumen Intl

Fri 2/27

4:41 pm-9:46 pm

1 stop29h 05m

Louisville Intl

Wed 3/25

6:00 am-6:38 pm

1 stop13h 38m

$474

Panama CityLouisville

PTY - SDF

PTYSDF

Panama City Tocumen Intl

Wed 4/1

7:55 am-8:00 pm

1 stop11h 05m

$269

Panama CityLouisville

PTY - SDF

PTYSDF

Panama City Tocumen Intl

Sun 4/5

3:30 pm-9:59 pm

1 stop29h 29m

$269

Panama CityLouisville

PTY - SDF

PTYSDF

Panama City Tocumen Intl

Thu 4/2

10:00 am-9:59 pm

1 stop10h 59m

$269

Panama CityLouisville

PTY - SDF

PTYSDF

Panama City Tocumen Intl

Tue 4/7

3:30 pm-1:36 pm

1 stop21h 06m

$269

Flights are sorted by cheapest round-trip flights first.

Deals found on 1/28

Showing 1-10 of 15 results
1
2

Best time to book a flight from Panama to Louisville

Have a flexible travel schedule? Discover the best time to fly to Louisville from Panama with our price prediction graph.
Estimated round-trip price
Rates are based on past data. Find the cheapest month and day to book your flight based on your travel requirements, then search for cheap deals.

Cheapflights Insights

Everything you need to know about your flight from Panama to Louisville

What is the cheapest month to book a flight from Panama to Louisville?

Currently, August is the cheapest month in which you can book a flight from Panama to Louisville (average of $217). Flying from Panama to Louisville in January is currently the most expensive (average of $521). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.

Reviews of airlines servicing Louisville

Get insights into the airlines that provide service to Louisville. Read reviews, discover amenities, and learn about the overall travel experience offered by airlines. Use this information to make informed decisions when choosing an airline for your flight to Louisville. Reviews last updated January 29, 2026.
Peruse reviews from past customers who have flown with United Airlines from Panama to Louisville to help guide your decision. You can also see how each airline stacks up in terms of entertainment options, comfort, food, crew/service, and boarding process.
United Airlines
7.4
Good
9,215 reviews

Crew

8.1

Boarding

7.7

Comfort

7.3

Entertainment

7.1

Food

6.6

Overall

7.4

Reviews

1 / 20
6.0
Good

Gerry,Jan 2026

YVR - DEN

Seats were uncomfortable. Second leg of my flight on United had much more comfortable seats
United Airlines
7.4
Good
9,215 reviews
United Airlines
7.4
Good
9,215 reviews

Crew

8.1

Boarding

7.7

Comfort

7.3

Entertainment

7.1

Food

6.6

Overall

7.4

Reviews

1 / 20
6.0
Good

Gerry,Jan 2026

YVR - DEN

Seats were uncomfortable. Second leg of my flight on United had much more comfortable seats

Related info for your journey

Find useful and relevant information for your journey from Panama to Louisville. Access travel guides, tips, and recommendations to enhance your travel experience. Get information about local attractions, weather, transportation options, and more.

  • What airport do you fly into for flights to Louisville from Panama?

    Located just 5.3 mi from the city center, Louisville Intl (SDF) is the airport most travelers will use when flying to Louisville from Panama.

  • How long is the flight from Panama to Louisville?

    A quick flight from Panama to Louisville can take about 7h 23m. Delta provides one of the quickest options available for as low as $472. Panama and Louisville are separated by a distance of 2048 mi. This flight may include one or multiple stops.

  • Can I find deals for flights from Panama to Louisville that include hotel bookings?

    Yes. In addition to deals on Panama to Louisville flights, Cheapflights offers vacation packages that include both flights and hotel.

  • How can I find direct flights from Panama to Louisville?

    After entering your origin and destination, apply the non-stop filter on the search result page to find direct flights from Panama to Louisville.

  • Can I find deals for business class flights from Panama to Louisville?

    Yes. Cheapflights offers flight deals from Panama to Louisville by cabin class. In addition to browsing deals, you can also filter by cabin class on the search results page after making a search.

  • What is the cheapest month to book a flight from Panama to Louisville?

    Currently, August is the cheapest month in which you can book a flight from Panama to Louisville (average of $217). Flying from Panama to Louisville in January is currently the most expensive (average of $521). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.

See more FAQs

Traveling to a place near Louisville?

Book flights to Louisville if you plan to visit one of these locations
Shepherdsville
Jeffersonville
Elizabethtown
Corydon
Bardstown

Browse thousands of different options on Cheapflights for your next trip

Toggle through the tabs below to find thousands of options on Cheapflights for your next trip.

Alternative routes for Panama to Louisville

See prices for flight routes from nearby airports that may be better suited for you.
Guatemala City to Nashville flights
San José to Nashville flights
San Pedro Sula to Nashville flights
San Salvador to Nashville flights
Panama City to Louisville flights
San José to Cincinnati flights
San José to Louisville flights
Panama City to Nashville flights
San Salvador to Knoxville flights
San José to Lexington flights
San Salvador to Cincinnati flights
Guatemala City to Louisville flights
San Pedro Sula to Louisville flights
Managua to Nashville flights
Panama City to Cincinnati flights
Guatemala City to Cincinnati flights
San José to Knoxville flights
Tegucigalpa to Nashville flights
Philip S.W.Goldson to Nashville flights
Managua to Louisville flights
Liberia to Nashville flights
Tegucigalpa to Knoxville flights
Tegucigalpa to Louisville flights
Tegucigalpa to Cincinnati flights

Top airline flying from Panama to Louisville

Discover the top airline that operate flights from Panama to Louisville. Compare their services, reliability, and customer satisfaction ratings to choose the airline that best suits your travel preferences and needs. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated January 29, 2026.
AirlineCheapestAverageFlexibilityOn-time
United AirlinesCheapest$366Average$617FlexibilityNo cancel feeOn-time69%

100% Free

Cheapflights is completely free to use, so you can start saving the moment you arrive.

Book with Flexibility

Our users can plan ahead with confidence and find flights with no change fees

Travel Smart

Millions of people come to us for their flight needs every year. We help make travel planning easy by providing useful insights and data-driven graphs that can inform your decisions.