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$458+ Cheap flights from Panama to Louisville (SDF)

This is the cheapest round-trip flight price found by a Cheapflights user in the last 72 hours by searching for a flight departing on 3/6. Fares are subject to change and may not be available on all flights or dates of travel.
PTY — SDF
Nov 29 — Dec 61
Sat 11/29
Sat 12/6
1 adult, Economy
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Cheap flight deals from Panama to Louisville

Keep the following information in mind while searching for Panama to Louisville flight deals. Data was last updated October 30, 2025.

Most accurate provider

eDreams
3 stars

Most trusted provider

eDreams
3 stars

Round-trip from

$783
(American Airlines)

Popular in

January

Cheapest in

October

Average price

$468
Provider with most accurate pricing for Panama City Tocumen Intl-Louisville Intl flight deals.
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Provider most trusted by Cheapflights users for Panama City Tocumen Intl-Louisville Intl flights.
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From Panama to Louisville Intl
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Highest demand for flights based on searches. 15% potential increase in price ($104 potential increase over avg. RT price).
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Cheapest flight prices on average. 7% potential price decrease ($43 potential savings vs. average RT price).
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Average for round-trip flights in October 2025
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Find flight deals from Panama to Louisville

Cheapest flights from Panama to Louisville
Explore the most affordable flight options available from Panama to Louisville. Find the lowest fares from popular airlines and budget airlines, with prices last updated on October 30, 2025.

This Delta deal was found by Cheapflights users on 10/28. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 11/53:21 pmPTY - SDF
1 stop7h 13mDelta
Sat 11/298:35 amSDF - PTY
1 stop11h 24mDelta
Deal found 10/28$545
This American Airlines deal was found by Cheapflights users on 10/28. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 11/172:49 pmPTY - SDF
2 stops19h 22mAmerican Airlines
Sun 11/307:31 pmSDF - PTY
2 stops18h 12mAmerican Airlines
Deal found 10/28$625
This United Airlines deal was found by Cheapflights users on 10/29. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 10/313:41 pmPTY - SDF
1 stop20h 44mUnited Airlines
Mon 11/39:00 amSDF - PTY
2 stops10h 38mUnited Airlines
Deal found 10/29$657
This United Airlines deal was found by Cheapflights users on 10/28. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 11/58:55 amPTY - SDF
2 stops13h 34mUnited Airlines
Sat 11/297:10 amSDF - PTY
1 stop12h 28mUnited Airlines
Deal found 10/28$686
This American Airlines deal was found by Cheapflights users on 10/28. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 11/52:49 pmPTY - SDF
2 stops25h 40mAmerican Airlines
Sat 11/2912:43 pmSDF - PTY
2 stops25h 00mAmerican Airlines
Deal found 10/28$714
This Mytrip deal was found by Cheapflights users on 10/28. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Mytrip is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 11/162:55 amPTY - SDF
2 stops16h 01mMultiple Airlines
Sun 11/308:31 pmSDF - PTY
3 stops28h 09mMultiple Airlines
Deal found 10/28$831
This United Airlines deal was found by Cheapflights users on 10/29. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 10/319:30 amPTY - SDF
2 stops23h 28mUnited Airlines
Sat 11/13:35 pmSDF - PTY
1 stop24h 10mUnited Airlines
Deal found 10/29$1,149
This Mytrip deal was found by Cheapflights users on 10/29. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Mytrip is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 10/302:55 amPTY - SDF
3 stops29h 39mMultiple Airlines
Mon 11/312:21 pmSDF - PTY
3 stops25h 39mMultiple Airlines
Deal found 10/29$1,173
This Mytrip deal was found by Cheapflights users on 10/28. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Mytrip is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 11/55:50 pmPTY - SDF
2 stops26h 13mMultiple Airlines
Sat 11/297:50 amSDF - PTY
3 stops35h 05mMultiple Airlines
Deal found 10/28$1,239

Cheapflights Fare Finder

 
Customize your flight search to find flights from Panama to Louisville that fit within your specific budget. Explore options based on user searches and filter the results based on your desired price range. Find flights that match your budget for a cost-effective journey. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated October 30, 2025.
Use the filters below to find and compare flights from Panama to Louisville that are best for you.

Fly from

Panama

Fly to

Louisville

Route

Depart

Return

Price

Panama CityLouisville

PTY - SDF

PTYSDF

Panama City Tocumen Intl

Fri 3/6

8:55 am-9:30 pm

1 stop12h 35m

Louisville Intl

Tue 3/10

6:00 am-4:07 pm

1 stop11h 07m

$458

Panama CityLouisville

PTY - SDF

PTYSDF

Panama City Tocumen Intl

Mon 11/17

2:49 pm-10:11 am

2 stops19h 22m

Louisville Intl

Sun 11/30

7:31 pm-1:43 pm

2 stops18h 12m

$625

Panama CityLouisville

PTY - SDF

PTYSDF

Panama City Tocumen Intl

Mon 1/5

4:55 pm-2:48 pm

2 stops21h 53m

Louisville Intl

Thu 1/22

6:00 am-1:27 pm

1 stop7h 27m

$783

Panama CityLouisville

PTY - SDF

PTYSDF

Panama City Tocumen Intl

Sun 11/16

2:55 am-6:56 pm

2 stops16h 01m

Louisville Intl

Sun 11/30

8:31 pm-12:40 am

3 stops28h 09m

$831

Panama CityLouisville

PTY - SDF

PTYSDF

Panama City Tocumen Intl

Mon 1/5

3:50 pm-10:49 pm

3 stops30h 59m

Louisville Intl

Thu 1/22

6:00 am-1:00 am

2 stops19h 00m

$891

Panama CityLouisville

PTY - SDF

PTYSDF

Panama City Tocumen Intl

Mon 1/5

3:20 pm-11:55 pm

1 stop8h 35m

Louisville Intl

Thu 1/22

5:35 am-1:55 pm

1 stop8h 20m

$906

Flights are sorted by cheapest round-trip flights first.

Deals found on 10/27

Best time to book a flight from Panama to Louisville

Have a flexible travel schedule? Discover the best time to fly to Louisville from Panama with our price prediction graph.
Estimated round-trip price
Rates are based on past data. Find the cheapest month and day to book your flight based on your travel requirements, then search for cheap deals.

Cheapflights Insights

Everything you need to know about your flight from Panama to Louisville

What is the cheapest month to book a flight from Panama to Louisville?

Currently, August is the cheapest month in which you can book a flight from Panama to Louisville (average of $221). Flying from Panama to Louisville in January is currently the most expensive (average of $563). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.

What is the cheapest time of day to fly from PA to SDF?

Find hourly flight availability from Panama to Louisville. Discover flight options and departure times throughout the day, allowing you to choose a departure time that suits your schedule. Data last updated October 30, 2025.

A simple way to save on the total cost of your ticket is to fly from Panama to Louisville in the evening. If you’re flexible enough to do this you can expect to save up to 23% on your trip compared to booking a flight in the morning.

Reviews of airlines servicing Louisville

Get insights into the airlines that provide service to Louisville. Read reviews, discover amenities, and learn about the overall travel experience offered by airlines. Use this information to make informed decisions when choosing an airline for your flight to Louisville. Reviews last updated October 30, 2025.
Peruse reviews from past customers who have flown with Delta, United Airlines, and American Airlines from Panama to Louisville to help guide your decision. You can also see how each airline stacks up in terms of entertainment options, comfort, food, crew/service, and boarding process.
Delta
7.9
Good
7,998 reviews

Crew

8.5

Comfort

7.9

Food

7.3

Entertainment

7.9

Boarding

8.2

Overall

7.9

Reviews

1 / 20
10.0
Excellent

Mary,Oct 2025

AMS - PDX

It's specail being able to fly non-stop from Amsterdam all the way home to Portland, Oregon!
Delta
7.9
Good
7,998 reviews
Delta
7.9
Good
7,998 reviews

Crew

8.5

Comfort

7.9

Food

7.3

Entertainment

7.9

Boarding

8.2

Overall

7.9

Reviews

1 / 20
10.0
Excellent

Mary,Oct 2025

AMS - PDX

It's specail being able to fly non-stop from Amsterdam all the way home to Portland, Oregon!
United Airlines
7.4
Good
8,998 reviews
Delta
7.9
Good
7,998 reviews

Crew

8.5

Comfort

7.9

Food

7.3

Entertainment

7.9

Boarding

8.2

Overall

7.9

Reviews

1 / 20
10.0
Excellent

Mary,Oct 2025

AMS - PDX

It's specail being able to fly non-stop from Amsterdam all the way home to Portland, Oregon!
American Airlines
7.2
Good
11,035 reviews
Delta
7.9
Good
7,998 reviews

Crew

8.5

Comfort

7.9

Food

7.3

Entertainment

7.9

Boarding

8.2

Overall

7.9

Reviews

1 / 20
10.0
Excellent

Mary,Oct 2025

AMS - PDX

It's specail being able to fly non-stop from Amsterdam all the way home to Portland, Oregon!

Related info for your journey

Find useful and relevant information for your journey from Panama to Louisville. Access travel guides, tips, and recommendations to enhance your travel experience. Get information about local attractions, weather, transportation options, and more.

  • What airport do you fly into for flights to Louisville from Panama?

    Located just 5.3 mi from the city center, Louisville Intl (SDF) is the airport most travelers will use when flying to Louisville from Panama.

  • How long is the flight from Panama to Louisville?

    A quick flight from Panama to Louisville can take about 12h 35m. United Airlines provides one of the quickest options available for as low as $458. Panama and Louisville are separated by a distance of 2048 mi. This flight may include one or multiple stops.

  • Can I find deals for flights from Panama to Louisville that include hotel bookings?

    Yes. In addition to deals on Panama to Louisville flights, Cheapflights offers vacation packages that include both flights and hotel.

  • How can I find direct flights from Panama to Louisville?

    After entering your origin and destination, apply the non-stop filter on the search result page to find direct flights from Panama to Louisville.

  • Can I find deals for business class flights from Panama to Louisville?

    Yes. Cheapflights offers flight deals from Panama to Louisville by cabin class. In addition to browsing deals, you can also filter by cabin class on the search results page after making a search.

  • What is the cheapest month to book a flight from Panama to Louisville?

    Currently, August is the cheapest month in which you can book a flight from Panama to Louisville (average of $221). Flying from Panama to Louisville in January is currently the most expensive (average of $563). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.

See more FAQs

Traveling to a place near Louisville?

Book flights to Louisville if you plan to visit one of these locations
Shepherdsville
Jeffersonville
Elizabethtown
Corydon
Bardstown

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Alternative routes for Panama to Louisville

See prices for flight routes from nearby airports that may be better suited for you.
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Top 3 airlines flying from Panama to Louisville

Discover the top 3 airlines that operate flights from Panama to Louisville. Compare their services, reliability, and customer satisfaction ratings to choose the airline that best suits your travel preferences and needs. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated October 30, 2025.
AirlineCheapestAverageFlexibilityOn-time
DeltaCheapest$338Average$526FlexibilityNo cancel feeOn-timeN/A
United AirlinesCheapest$366Average$557FlexibilityNo cancel feeOn-time69%
American AirlinesCheapest$370Average$627FlexibilityNo cancel feeOn-time71%

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