HomeSearch by dateVacation packagesHotelsFlight dealsCar rentalTravel tips & news
Louisville

$354+ Cheap flights from Medford to Louisville (MFR - SDF)

This is the cheapest round-trip flight price found by a Cheapflights user in the last 72 hours by searching for a flight departing on 11/14. Fares are subject to change and may not be available on all flights or dates of travel.
MFR — SDF
Aug 25 — Sep 11
Mon 8/25
Mon 9/1
1 adult, Economy
We work with more than 300 partners to bring you better travel deals

Find cheap flights from Medford to Louisville with Cheapflights

1. Tell us where you want to go

Enter your travel information like dates, passengers, trip type (one-way or round trip), and preferred cabin class then click “Find deals”

2. Select your favorite providers

We find the providers serving your travel needs. Choose up to four travel providers to compare side-by-side for flights, hotels, or car rentals.

3. Compare prices and book

Review each provider’s pricing and select the best option for you! Book through your favorite provider’s website for a seamless experience.

Cheap flight deals from Medford to Louisville

Discover tips and strategies to find the most affordable flight options for your journey from Medford (MFR) to Louisville (SDF). Learn about various techniques such as flexible date searches, comparing prices across and setting up price alerts. Use these methods to find the cheapest flights available for your travel needs. Data last updated August 20, 2025.

Round-trip from

$354
(Delta)

Popular in

September

Cheapest in

January

Average price

$416
From Medford to Louisville Intl
Search Deals
Highest demand for flights based on searches. 7% potential increase in price ($49 potential increase over avg. RT price).
Search Deals
Cheapest flight prices on average. 8% potential price decrease ($49 potential savings vs. average RT price).
Search Deals
Average for round-trip flights in August 2025
Search Deals

Find flight deals from Medford to Louisville

Cheapest flights from Medford to Louisville
Explore the most affordable flight options available from Medford to Louisville. Find the lowest fares from popular airlines and budget airlines, with prices last updated on August 20, 2025.

This Delta deal was found by Cheapflights users on 8/20. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 11/1411:23 amMFR - SDF
2 stops9h 33mDelta
Mon 11/171:20 pmSDF - MFR
2 stops13h 24mDelta
Deal found 8/20$354
This United Airlines deal was found by Cheapflights users on 8/18. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 10/226:37 pmMFR - SDF
2 stops12h 24mUnited Airlines
Fri 10/313:20 pmSDF - MFR
1 stop8h 54mUnited Airlines
Deal found 8/18$384
This United Airlines deal was found by Cheapflights users on 8/18. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 9/51:03 pmMFR - SDF
1 stop6h 27mUnited Airlines
Tue 9/93:30 pmSDF - MFR
1 stop8h 34mUnited Airlines
Deal found 8/18$404
This United Airlines deal was found by Cheapflights users on 8/18. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 9/31:03 pmMFR - SDF
1 stop6h 27mUnited Airlines
Sat 9/1310:55 amSDF - MFR
2 stops14h 24mUnited Airlines
Deal found 8/18$409
This United Airlines deal was found by Cheapflights users on 8/20. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 9/45:00 amMFR - SDF
2 stops10h 58mUnited Airlines
Mon 9/81:00 pmSDF - MFR
2 stops11h 04mUnited Airlines
Deal found 8/20$416
This Alaska Airlines deal was found by Cheapflights users on 8/18. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Alaska Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 9/45:14 amMFR - SDF
2 stops11h 10mAlaska Airlines
Mon 9/812:25 pmSDF - MFR
2 stops13h 36mAlaska Airlines
Deal found 8/18$439
This United Airlines deal was found by Cheapflights users on 8/20. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 11/146:36 pmMFR - SDF
2 stops14h 53mUnited Airlines
Mon 11/179:00 amSDF - MFR
3 stops16h 30mUnited Airlines
Deal found 8/20$459

Cheapflights Fare Finder

 
Customize your flight search to find flights from Medford to Louisville that fit within your specific budget. Explore options based on user searches and filter the results based on your desired price range. Find flights that match your budget for a cost-effective journey. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated August 20, 2025.
Use the filters below to find and compare flights from Medford to Louisville that are best for you.

Fly from

Medford

Fly to

Louisville

Route

Depart

Return

Price

MedfordLouisville

MFR - SDF

MFRSDF

Medford

Fri 11/14

11:23 am-11:56 pm

2 stops9h 33m

Louisville Intl

Mon 11/17

1:20 pm-11:44 pm

2 stops13h 24m

$354

MedfordLouisville

MFR - SDF

MFRSDF

Medford

Fri 11/14

6:36 pm-9:58 am

2 stops12h 22m

Louisville Intl

Mon 11/17

3:20 pm-9:14 pm

1 stop8h 54m

$384

MedfordLouisville

MFR - SDF

MFRSDF

Medford

Wed 10/22

6:37 pm-10:01 am

2 stops12h 24m

Louisville Intl

Fri 10/31

3:20 pm-9:14 pm

1 stop8h 54m

$384

MedfordLouisville

MFR - SDF

MFRSDF

Medford

Thu 9/4

5:00 am-6:58 pm

2 stops10h 58m

Louisville Intl

Mon 9/8

3:30 pm-9:04 pm

1 stop8h 34m

$384

MedfordLouisville

MFR - SDF

MFRSDF

Medford

Fri 9/5

1:03 pm-10:30 pm

1 stop6h 27m

Louisville Intl

Tue 9/9

3:30 pm-9:04 pm

1 stop8h 34m

$404

MedfordLouisville

MFR - SDF

MFRSDF

Medford

Wed 9/3

5:15 am-6:40 pm

2 stops10h 25m

Louisville Intl

Sat 9/13

6:00 am-3:34 pm

2 stops12h 34m

$409

MedfordLouisville

MFR - SDF

MFRSDF

Medford

Wed 9/3

1:03 pm-10:30 pm

1 stop6h 27m

Louisville Intl

Sat 9/13

10:55 am-10:19 pm

2 stops14h 24m

$409

Flights are sorted by cheapest round-trip flights first.

Deals found on 8/20

Best time to book a flight from Medford to Louisville

Have a flexible travel schedule? Discover the best time to fly to Louisville from Medford with our price prediction graph.
Estimated round-trip price
Rates are based on past data. Find the cheapest month and day to book your flight based on your travel requirements, then search for cheap deals.

Cheapflights Insights

Everything you need to know about your flight from Medford to Louisville

What is the cheapest month to book a flight from Medford to Louisville?

Currently, January is the cheapest month in which you can book a flight from Medford to Louisville (average of $299). Flying from Medford to Louisville in April is currently the most expensive (average of $369). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.

Reviews of airlines servicing Louisville

Get insights into the airlines that provide service to Louisville. Read reviews, discover amenities, and learn about the overall travel experience offered by airlines. Use this information to make informed decisions when choosing an airline for your flight to Louisville. Reviews last updated August 20, 2025.
See what other customers who have flown with United Airlines from Medford to Louisville have to say. You can also see how each airline compares in terms of entertainment options, comfort, food, crew/service, and boarding process.
United Airlines
7.4
Good
8,928 reviews

Entertainment

7.1

Crew

8.1

Boarding

7.7

Overall

7.4

Comfort

7.3

Food

6.6

Reviews

1 / 20
2.0
Mediocre

Deb,Jan 2025

MKE - ORD

It was terrible! So much to say, but in a nutshell we used vouchers from United because our last trip with them was awful with many mishaps and errors made. Unfortunately, this trip was even worse!
United Airlines
7.4
Good
8,928 reviews
United Airlines
7.4
Good
8,928 reviews

Entertainment

7.1

Crew

8.1

Boarding

7.7

Overall

7.4

Comfort

7.3

Food

6.6

Reviews

1 / 20
2.0
Mediocre

Deb,Jan 2025

MKE - ORD

It was terrible! So much to say, but in a nutshell we used vouchers from United because our last trip with them was awful with many mishaps and errors made. Unfortunately, this trip was even worse!

Related info for your journey

Find useful and relevant information for your journey from Medford to Louisville. Access travel guides, tips, and recommendations to enhance your travel experience. Get information about local attractions, weather, transportation options, and more.

  • How long is the flight from Medford to Louisville?

    A quick flight from Medford to Louisville can take about 9h 33m. Delta provides one of the quickest options available for as low as $354. Airlines will cover a distance of 1962 mi. When browsing for deals, the options you’ll see will be for both nonstop flights and flights with stops.

  • What is the cheapest airline to fly from Medford to Louisville round-trip?

    Cheapflights users have booked flights from Medford to Louisville round-trip from $313. United Airlines is currently priced 49% below the average price you’ll pay for this route.

  • Can I find deals for flights from Medford to Louisville that include hotel bookings?

    Yes. In addition to deals on Medford to Louisville flights, Cheapflights offers vacation packages that include both flights and hotel.

  • How can I find direct flights from Medford to Louisville?

    After entering your origin and destination, apply the non-stop filter on the search result page to find direct flights from Medford to Louisville.

  • Can I find deals for business class flights from Medford to Louisville?

    Yes. Cheapflights offers flight deals from Medford to Louisville by cabin class. In addition to browsing deals, you can also filter by cabin class on the search results page after making a search.

  • What is the cheapest month to book a flight from Medford to Louisville?

    Currently, January is the cheapest month in which you can book a flight from Medford to Louisville (average of $299). Flying from Medford to Louisville in April is currently the most expensive (average of $369). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.

See more FAQs

Traveling to a place near Louisville?

Book flights to Louisville if you plan to visit one of these locations
Shepherdsville
Jeffersonville
Elizabethtown
Corydon
Bardstown

Browse thousands of different options on Cheapflights for your next trip

Toggle through the tabs below to find thousands of options on Cheapflights for your next trip.

Alternative routes for Medford to Louisville

See prices for flight routes from nearby airports that may be better suited for you.
Portland to Nashville flights
Portland to Knoxville flights
Boise to Nashville flights
Portland to Louisville flights
Boise to Cincinnati flights
Eugene to Nashville flights
Boise to Knoxville flights
Portland to Cincinnati flights
Yakima to Louisville flights
Redmond to Nashville flights
Portland to Lexington flights
Medford to Nashville flights
Medford to Cincinnati flights
Boise to Louisville flights
Eugene to Knoxville flights
Medford to Knoxville flights
Redmond to Knoxville flights
Boise to Lexington flights
Redmond to Cincinnati flights
Portland to Blountville flights
Eugene to Cincinnati flights
Eugene to Lexington flights
Eugene to Louisville flights
Portland to Evansville flights
Redmond to Louisville flights
Eugene to Blountville flights
Redmond to Evansville flights
Redmond to Blountville flights
Boise to Paducah flights
Portland to Paducah flights
Portland to Huntington flights
Redmond to Huntington flights
Pendleton to Cincinnati flights
Yakima to Cincinnati flights

Top airline flying from Medford to Louisville

Discover the top airline that operate flights from Medford to Louisville. Compare their services, reliability, and customer satisfaction ratings to choose the airline that best suits your travel preferences and needs. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated August 20, 2025.
AirlineCheapestAverageFlexibilityOn-time
United AirlinesCheapest$313Average$627FlexibilityNo cancel feeOn-time69%

100% Free

Cheapflights is completely free to use, so you can start saving the moment you arrive.

Book with Flexibility

Our users can plan ahead with confidence and find flights with no change fees

Travel Smart

Millions of people come to us for their flight needs every year. We help make travel planning easy by providing useful insights and data-driven graphs that can inform your decisions.