$414+ Cheap flights from La Crosse to Louisville (LSE - SDF)
This is the cheapest round-trip flight price found by a Cheapflights user in the last 72 hours by searching for a flight departing on 3/7. Fares are subject to change and may not be available on all flights or dates of travel.
LSE — SDF
Dec 20 — Dec 271
1 adult, Economy
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1. Tell us where you want to go
Enter your travel information like dates, passengers, trip type (one-way or round trip), and preferred cabin class then click “Find deals”2. Select your favorite providers
We find the providers serving your travel needs. Choose up to four travel providers to compare side-by-side for flights, hotels, or car rentals.3. Compare prices and book
Review each provider’s pricing and select the best option for you! Book through your favorite provider’s website for a seamless experience.Cheap flight deals from La Crosse to Louisville
Discover tips and strategies to find the most affordable flight options for your journey from La Crosse (LSE) to Louisville (SDF). Learn about various techniques such as flexible date searches, comparing prices across and setting up price alerts. Use these methods to find the cheapest flights available for your travel needs. Data last updated November 20, 2025.
Most accurate provider | FlightHub 3 stars |
|---|---|
Most trusted provider | FlightHub 1 star |
Round-trip from | $414 (American Airlines) |
Find flight deals from La Crosse to Louisville
Cheapest flights from La Crosse to LouisvilleExplore the most affordable flight options available from La Crosse to Louisville. Find the lowest fares from popular airlines and budget airlines, with prices last updated on November 20, 2025.
Explore the most affordable flight options available from La Crosse to Louisville. Find the lowest fares from popular airlines and budget airlines, with prices last updated on November 20, 2025.
This American Airlines deal was found by Cheapflights users on 11/18. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 12/1310:00 amLSE - SDF
1 stop6h 51mAmerican Airlines
Tue 12/161:02 pmSDF - LSE
1 stop4h 10mAmerican Airlines
Deal found 11/18![American Airlines logo]()
$474
This American Airlines deal was found by Cheapflights users on 11/18. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 11/194:10 pmLSE - SDF
1 stop5h 45mAmerican Airlines
Sun 11/236:04 amSDF - LSE
1 stop4h 16mAmerican Airlines
Deal found 11/18![American Airlines logo]()
$517
This American Airlines deal was found by Cheapflights users on 11/19. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 12/46:00 amLSE - SDF
1 stop5h 30mAmerican Airlines
Mon 12/81:02 pmSDF - LSE
1 stop5h 38mAmerican Airlines
Deal found 11/19![American Airlines logo]()
$560
Cheapflights Fare Finder
Customize your flight search to find flights from La Crosse to Louisville that fit within your specific budget. Explore options based on user searches and filter the results based on your desired price range. Find flights that match your budget for a cost-effective journey. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated November 20, 2025.
Use the filters below to find and compare flights from La Crosse to Louisville that are best for you.
Fly from
La Crosse
Fly to
Louisville
Route
Depart
Return
Price
La CrosseLouisville
LSE - SDF
LSESDF
La Crosse
Sat 3/7
6:00 am-11:04 am
1 stop4h 04m
Louisville Intl
Wed 3/11
7:19 pm-9:40 pm
1 stop3h 21m
$414
La CrosseLouisville
LSE - SDF
LSESDF
La Crosse
Sat 3/7
6:00 am-11:04 am
1 stop4h 04m
Louisville Intl
Thu 3/12
7:19 pm-9:40 pm
1 stop3h 21m
$468
La CrosseLouisville
LSE - SDF
LSESDF
La Crosse
Sat 12/13
6:02 pm-10:56 pm
1 stop3h 54m
Louisville Intl
Tue 12/16
1:02 pm-4:12 pm
1 stop4h 10m
$474
La CrosseLouisville
LSE - SDF
LSESDF
La Crosse
Thu 12/4
6:00 am-12:30 pm
1 stop5h 30m
Louisville Intl
Mon 12/8
1:02 pm-5:40 pm
1 stop5h 38m
$560
- Most accurate provider: When it comes to deals on La Crosse-Louisville flights, users find the pricing of FlightHub to be most consistent on Cheapflights vs. FlightHub Users can find the same prices on La Crosse-Louisville flight deals on Cheapflights vs. FlightHub >95% of the time. Price accuracy is based on data collected from La Crosse-Louisville flight searches over the past month and is updated monthly.
- Most trusted provider: When it comes to deals on La Crosse-Louisville flights, Cheapflights users trust FlightHub the most. FlightHub has received a user feedback score of 3 out of 3 stars (3 being the best), meaning they have been trusted the most by Cheapflights users looking for La Crosse-Louisville flight deals. Provider user feedback score is based on Cheapflights searches over the past month and is updated monthly.
Best time to book a flight from La Crosse to Louisville
Have a flexible travel schedule? Discover the best time to fly to Louisville from La Crosse with our price prediction graph.
Estimated round-trip price
Rates are based on past data. Find the cheapest month and day to book your flight based on your travel requirements, then search for cheap deals.
Related info for your journey
Find useful and relevant information for your journey from La Crosse to Louisville. Access travel guides, tips, and recommendations to enhance your travel experience. Get information about local attractions, weather, transportation options, and more.
Traveling to a place near Louisville?
Book flights to Louisville if you plan to visit one of these locationsShepherdsville
Jeffersonville
Elizabethtown
Corydon
Bardstown