Louisiana

$102+ Cheap flights from Knoxville (TYS) to Louisiana

This is the cheapest one-way flight price found by a Cheapflights user in the last 72 hours by searching for a flight departing on 4/12. Fares are subject to change and may not be available on all flights or dates of travel.
TYS — MSY
apr 17 — apr 241
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Cheap flight deals from Knoxville to Louisiana

Cheapest flights from Knoxville to Louisiana
Explore the most affordable flight options available from Knoxville to Louisiana. Find the lowest fares from popular airlines and budget airlines, with prices last updated on marzo 18, 2026.

This Kiwi.com deal was found by Cheapflights users on 3/16. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
sab 4/410:00 am
TYS
-
MSY
1 stop9h 55m
Multiple Airlines
mar 4/77:18 pm
MSY
-
TYS
1 stop14h 18m
Multiple Airlines
Deal found 3/16$206
This Kiwi.com deal was found by Cheapflights users on 3/14. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
sab 4/119:00 am
TYS
-
MSY
1 stop10h 55m
Multiple Airlines
lun 4/134:38 pm
MSY
-
TYS
1 stop21h 20m
Multiple Airlines
Deal found 3/14$211
This Kiwi.com deal was found by Cheapflights users on 3/16. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
ven 4/175:39 pm
TYS
-
MSY
1 stop26h 16m
Multiple Airlines
gio 4/236:32 pm
MSY
-
TYS
2 stops26h 16m
Multiple Airlines
Deal found 3/16$215
This Kiwi.com deal was found by Cheapflights users on 3/17. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
dom 4/199:12 pm
TYS
-
MSY
1 stop19h 37m
Multiple Airlines
gio 4/235:15 am
MSY
-
TYS
1 stop14h 27m
Multiple Airlines
Deal found 3/17$216
This Kiwi.com deal was found by Cheapflights users on 3/13. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
sab 4/119:00 am
TYS
-
MSY
1 stop10h 23m
Multiple Airlines
sab 4/185:15 am
MSY
-
TYS
1 stop5h 51m
Multiple Airlines
Deal found 3/13$236
This Kiwi.com deal was found by Cheapflights users on 3/16. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
lun 3/306:20 am
TYS
-
MSY
1 stop11h 06m
Multiple Airlines
mar 3/317:10 pm
MSY
-
TYS
1 stop14h 26m
Multiple Airlines
Deal found 3/16$237
This Kiwi.com deal was found by Cheapflights users on 3/13. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
ven 4/175:39 pm
TYS
-
MSY
1 stop26h 16m
Multiple Airlines
mar 4/213:39 pm
MSY
-
TYS
1 stop17h 57m
Multiple Airlines
Deal found 3/13$242
This Kiwi.com deal was found by Cheapflights users on 3/13. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
gio 3/267:50 pm
TYS
-
MSY
1 stop21h 36m
Multiple Airlines
sab 3/286:00 am
MSY
-
TYS
1 stop13h 51m
Multiple Airlines
Deal found 3/13$247
This Kiwi.com deal was found by Cheapflights users on 3/15. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
mer 4/18:30 am
TYS
-
MSY
1 stop27h 59m
Multiple Airlines
sab 4/47:18 pm
MSY
-
TYS
1 stop27h 21m
Multiple Airlines
Deal found 3/15$252
This American Airlines deal was found by Cheapflights users on 3/13. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
ven 4/34:15 pm
TYS
-
BTR
1 stop6h 21m
American Airlines
ven 4/104:33 pm
BTR
-
TYS
1 stop4h 51m
American Airlines
Deal found 3/13$309
This American Airlines deal was found by Cheapflights users on 3/16. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
mar 3/316:31 pm
TYS
-
LFT
1 stop5h 27m
American Airlines
sab 4/46:16 pm
LFT
-
TYS
1 stop4h 35m
American Airlines
Deal found 3/16$319
This American Airlines deal was found by Cheapflights users on 3/13. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
sab 3/289:25 am
TYS
-
BTR
1 stop7h 36m
American Airlines
mer 4/15:57 pm
BTR
-
TYS
1 stop4h 54m
American Airlines
Deal found 3/13$319

Find flight deals from Knoxville to Louisiana

Keep the following information in mind while searching for Knoxville to Louisiana flight deals. Data was last updated marzo 18, 2026.

Most accurate provider

FlightHub
3 stars

Most trusted provider

FlightHub
3 stars

Round-trip from

$206
(Kiwi.com)

One-way from

$102
(Kiwi.com)

Popular in

February

Cheapest in

August

Average price

$424
Provider with most accurate pricing for Knoxville McGhee Tyson-New Orleans Louis Armstrong flight deals.
Provider most trusted by Cheapflights users for Knoxville McGhee Tyson-New Orleans Louis Armstrong flights.
From Knoxville McGhee Tyson to Louisiana
One-way flight from Knoxville McGhee Tyson to Louisiana
Highest demand for flights based on searches. 16% potential increase in price ($73 potential increase over avg. RT price).
Cheapest flight prices on average. 5% potential price decrease ($19 potential savings vs. average RT price).
Average for round-trip flights in March 2026

Cheapflights Fare Finder

 
Customize your flight search to find flights from Knoxville to Louisiana that fit within your specific budget. Explore options based on user searches and filter the results based on your desired price range. Find flights that match your budget for a cost-effective journey. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated marzo 18, 2026.
Use the filters below to find and compare flights from Knoxville to Louisiana that are best for you.

Fly from

Fly to

Route

Depart

Return

Price

Cheapest round-trip

KnoxvilleBaton Rouge

TYS - BTR

TYSBTR

Knoxville McGhee Tyson

ven 4/3

4:15 pm-9:36 pm

1 stop6h 21m

Baton Rouge Ryan

ven 4/10

4:33 pm-10:24 pm

1 stop4h 51m

$309

KnoxvilleNew Orleans

TYS - MSY

TYSMSY

Knoxville McGhee Tyson

sab 4/11

6:40 am-9:15 am

1 stop3h 35m

New Orleans Louis Armstrong

mar 4/14

8:25 am-2:20 pm

1 stop4h 55m

$309

KnoxvilleBaton Rouge

TYS - BTR

TYSBTR

Knoxville McGhee Tyson

ven 5/1

4:09 pm-10:46 pm

1 stop7h 37m

Baton Rouge Ryan

dom 5/3

5:40 am-12:30 pm

1 stop5h 50m

$309

KnoxvilleBaton Rouge

TYS - BTR

TYSBTR

Knoxville McGhee Tyson

mar 3/31

8:50 am-12:51 pm

1 stop5h 01m

Baton Rouge Ryan

sab 4/4

5:00 am-11:30 am

1 stop5h 30m

$319

KnoxvilleNew Orleans

TYS - MSY

TYSMSY

Knoxville McGhee Tyson

sab 4/11

7:45 am-6:55 pm

2 stops12h 10m

New Orleans Louis Armstrong

sab 4/18

8:30 am-6:30 pm

2 stops9h 00m

$325

KnoxvilleBaton Rouge

TYS - BTR

TYSBTR

Knoxville McGhee Tyson

mer 4/22

7:05 am-1:25 pm

1 stop7h 20m

Baton Rouge Ryan

sab 4/25

12:00 pm-7:56 pm

1 stop6h 56m

$329

KnoxvilleNew Orleans

TYS - MSY

TYSMSY

Knoxville McGhee Tyson

ven 4/17

6:45 pm-11:35 pm

2 stops5h 50m

New Orleans Louis Armstrong

mar 4/21

10:35 am-7:40 pm

2 stops8h 05m

$337
Quickest round-trip

KnoxvilleAlexandria

TYS - AEX

TYSAEX

Knoxville McGhee Tyson

ven 4/24

7:00 pm-9:43 pm

1 stop3h 43m

Alexandria

dom 4/26

6:08 am-11:17 am

1 stop4h 09m

$338

KnoxvilleNew Orleans

TYS - MSY

TYSMSY

Knoxville McGhee Tyson

gio 5/7

6:35 am-2:10 pm

2 stops8h 35m

New Orleans Louis Armstrong

dom 5/10

5:20 am-3:15 pm

1 stop8h 55m

$354

KnoxvilleAlexandria

TYS - AEX

TYSAEX

Knoxville McGhee Tyson

mar 8/25

3:25 pm-7:38 pm

1 stop5h 13m

Alexandria

sab 8/29

4:05 pm-9:30 pm

1 stop4h 25m

$358

Flights are sorted by cheapest round-trip flights first.

Deals found on 3/13

Showing 1-10 of 41 resultsSorted by cheapest first
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Best time to book a flight from Knoxville to Louisiana

Have a flexible travel schedule? Discover the best time to fly to Louisiana from Knoxville with our price prediction graph.
Estimated round-trip price
Rates are based on past data. Find the cheapest month and day to book your flight based on your travel requirements, then search for cheap deals.

Cheapflights Insights

Everything you need to know about your flight from Knoxville to Louisiana

What is the cheapest month to book a flight from Knoxville to Louisiana?

Currently, August is the cheapest month in which you can book a flight from Knoxville to Louisiana (average of $156). Flying from Knoxville to Louisiana in February is currently the most expensive (average of $269). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.

Reviews of airlines servicing Louisiana

Get insights into the airlines that provide service to Louisiana. Read reviews, discover amenities, and learn about the overall travel experience offered by airlines. Use this information to make informed decisions when choosing an airline for your flight to Louisiana. Reviews last updated marzo 18, 2026.
See what other customers who have flown with Southwest,Delta, andAmerican Airlines from Knoxville to Louisiana have to say. Users can see the overall rating for each airline as well as how each is rated in terms of entertainment options, comfort, food, crew/service, and boarding process.

Crew

8.6

Comfort

8.0

Boarding

8.1

Entertainment

7.5

Overall

8.0

Food

7.0

Reviews

1 / 20
10.0
Excellent

Anonymous,Mar 2026

KOA - HNL

pretty smooth and fast service ever, that flight is very helpful each and everyone for price and also fright for free..

Crew

8.6

Comfort

8.0

Boarding

8.1

Entertainment

7.5

Overall

8.0

Food

7.0

Reviews

1 / 20
10.0
Excellent

Anonymous,Mar 2026

KOA - HNL

pretty smooth and fast service ever, that flight is very helpful each and everyone for price and also fright for free..

Crew

8.6

Comfort

8.0

Boarding

8.1

Entertainment

7.5

Overall

8.0

Food

7.0

Reviews

1 / 20
10.0
Excellent

Anonymous,Mar 2026

KOA - HNL

pretty smooth and fast service ever, that flight is very helpful each and everyone for price and also fright for free..

Crew

8.6

Comfort

8.0

Boarding

8.1

Entertainment

7.5

Overall

8.0

Food

7.0

Reviews

1 / 20
10.0
Excellent

Anonymous,Mar 2026

KOA - HNL

pretty smooth and fast service ever, that flight is very helpful each and everyone for price and also fright for free..

Related info for your journey

Find useful and relevant information for your journey from Knoxville to Louisiana. Access travel guides, tips, and recommendations to enhance your travel experience. Get information about local attractions, weather, transportation options, and more.
  • What airport do you fly from for flights from Knoxville to Louisiana?

    Located just 11.3 mi from the city center, Knoxville McGhee Tyson (TYS) is the airport most travelers will use when flying to Louisiana from Knoxville.

  • How long is the flight from Knoxville to Louisiana?

    There are many flights that can get you from Knoxville to Louisiana in 3h 35m. Fly via American Airlines, Southwest, or United Airlines to get the fastest option. There are 541 mi between Knoxville and Louisiana. Both multi-stop and nonstop flights can be found to your destination and back.

  • What are the cheapest airlines to fly from Knoxville to Louisiana one-way?

    $99 is the cheapest one-way deal found within the past few days, from American Airlines. You may also be able to find cheap deals on Delta and United Airlines, with prices starting from $125 and $162, respectively.

  • What are the most popular routes from Knoxville to Louisiana?

  • Can I find deals for flights from Knoxville to Louisiana that include hotel bookings?

    Yes. In addition to deals on Knoxville to Louisiana flights, Cheapflights offers vacation packages that include both flights and hotel.

  • How can I find direct flights from Knoxville to Louisiana?

    After entering your origin and destination, apply the non-stop filter on the search result page to find direct flights from Knoxville to Louisiana.

  • Can I find deals for business class flights from Knoxville to Louisiana?

    Yes. Cheapflights offers flight deals from Knoxville to Louisiana by cabin class. In addition to browsing deals, you can also filter by cabin class on the search results page after making a search.

  • What is the cheapest month to book a flight from Knoxville to Louisiana?

    Currently, August is the cheapest month in which you can book a flight from Knoxville to Louisiana (average of $156). Flying from Knoxville to Louisiana in February is currently the most expensive (average of $269). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.

See more FAQs

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Alternative routes for Knoxville to Louisiana

See prices for flight routes from nearby airports that may be better suited for you.

Top 3 airlines flying from Knoxville to Louisiana

Discover the top 3 airlines that operate flights from Knoxville to Louisiana. Compare their services, reliability, and customer satisfaction ratings to choose the airline that best suits your travel preferences and needs. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated marzo 18, 2026.
AirlineCheapestAverageFlexibilityOn-time
American AirlinesCheapest$223Average$381FlexibilityNo cancel feeOn-time71%
DeltaCheapest$248Average$428FlexibilityNo cancel feeOn-timeN/A
SouthwestCheapest$306Average$363FlexibilityNo cancel feeOn-time63%

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