$102+ Cheap flights from Knoxville (TYS) to Louisiana
This is the cheapest one-way flight price found by a Cheapflights user in the last 72 hours by searching for a flight departing on 4/12. Fares are subject to change and may not be available on all flights or dates of travel.
TYS — MSY
apr 17 — apr 241
Round-trip
1 adult, Economy
We work with more than 300 partners to bring you better travel deals
Find cheap flights from Knoxville to Louisiana with Cheapflights
1. Tell us where you want to go
Enter your travel information like dates, passengers, trip type (one-way or round trip), and preferred cabin class then click “Find deals”2. Select your favorite providers
We find the providers serving your travel needs. Choose up to four travel providers to compare side-by-side for flights, hotels, or car rentals.3. Compare prices and book
Review each provider’s pricing and select the best option for you! Book through your favorite provider’s website for a seamless experience.Cheap flight deals from Knoxville to Louisiana
Cheapest
Best
Last-minute
One-way
Cheapest flights from Knoxville to LouisianaExplore the most affordable flight options available from Knoxville to Louisiana. Find the lowest fares from popular airlines and budget airlines, with prices last updated on marzo 18, 2026.
Explore the most affordable flight options available from Knoxville to Louisiana. Find the lowest fares from popular airlines and budget airlines, with prices last updated on marzo 18, 2026.
This Kiwi.com deal was found by Cheapflights users on 3/16. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
sab 4/410:00 am
TYS
- MSY
1 stop9h 55m
Multiple Airlines
mar 4/77:18 pm
MSY
- TYS
1 stop14h 18m
Multiple Airlines
Deal found 3/16![Multiple Airlines logo]()
$206
This Kiwi.com deal was found by Cheapflights users on 3/14. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
sab 4/119:00 am
TYS
- MSY
1 stop10h 55m
Multiple Airlines
lun 4/134:38 pm
MSY
- TYS
1 stop21h 20m
Multiple Airlines
Deal found 3/14![Multiple Airlines logo]()
$211
This Kiwi.com deal was found by Cheapflights users on 3/16. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
ven 4/175:39 pm
TYS
- MSY
1 stop26h 16m
Multiple Airlines
gio 4/236:32 pm
MSY
- TYS
2 stops26h 16m
Multiple Airlines
Deal found 3/16![Multiple Airlines logo]()
$215
This Kiwi.com deal was found by Cheapflights users on 3/17. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
dom 4/199:12 pm
TYS
- MSY
1 stop19h 37m
Multiple Airlines
gio 4/235:15 am
MSY
- TYS
1 stop14h 27m
Multiple Airlines
Deal found 3/17![Multiple Airlines logo]()
$216
This Kiwi.com deal was found by Cheapflights users on 3/13. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
sab 4/119:00 am
TYS
- MSY
1 stop10h 23m
Multiple Airlines
sab 4/185:15 am
MSY
- TYS
1 stop5h 51m
Multiple Airlines
Deal found 3/13![Multiple Airlines logo]()
$236
This Kiwi.com deal was found by Cheapflights users on 3/16. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
lun 3/306:20 am
TYS
- MSY
1 stop11h 06m
Multiple Airlines
mar 3/317:10 pm
MSY
- TYS
1 stop14h 26m
Multiple Airlines
Deal found 3/16![Multiple Airlines logo]()
$237
This Kiwi.com deal was found by Cheapflights users on 3/13. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
ven 4/175:39 pm
TYS
- MSY
1 stop26h 16m
Multiple Airlines
mar 4/213:39 pm
MSY
- TYS
1 stop17h 57m
Multiple Airlines
Deal found 3/13![Multiple Airlines logo]()
$242
This Kiwi.com deal was found by Cheapflights users on 3/13. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
gio 3/267:50 pm
TYS
- MSY
1 stop21h 36m
Multiple Airlines
sab 3/286:00 am
MSY
- TYS
1 stop13h 51m
Multiple Airlines
Deal found 3/13![Multiple Airlines logo]()
$247
This Kiwi.com deal was found by Cheapflights users on 3/15. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
mer 4/18:30 am
TYS
- MSY
1 stop27h 59m
Multiple Airlines
sab 4/47:18 pm
MSY
- TYS
1 stop27h 21m
Multiple Airlines
Deal found 3/15![Multiple Airlines logo]()
$252
This American Airlines deal was found by Cheapflights users on 3/13. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
ven 4/34:15 pm
TYS
- BTR
1 stop6h 21m
American Airlines
ven 4/104:33 pm
BTR
- TYS
1 stop4h 51m
American Airlines
Deal found 3/13![American Airlines logo]()
$309
This American Airlines deal was found by Cheapflights users on 3/16. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
mar 3/316:31 pm
TYS
- LFT
1 stop5h 27m
American Airlines
sab 4/46:16 pm
LFT
- TYS
1 stop4h 35m
American Airlines
Deal found 3/16![American Airlines logo]()
$319
This American Airlines deal was found by Cheapflights users on 3/13. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
sab 3/289:25 am
TYS
- BTR
1 stop7h 36m
American Airlines
mer 4/15:57 pm
BTR
- TYS
1 stop4h 54m
American Airlines
Deal found 3/13![American Airlines logo]()
$319
Best flights from Knoxville to LouisianaDiscover carefully curated flight deals from Knoxville to Louisiana that have cost, travel time, and layovers in mind to ensure you get the best travel experience. Data last updated marzo 18, 2026.
Discover carefully curated flight deals from Knoxville to Louisiana that have cost, travel time, and layovers in mind to ensure you get the best travel experience. Data last updated marzo 18, 2026.
This American Airlines deal was found by Cheapflights users on 3/13. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
ven 4/34:15 pm
TYS
- BTR
1 stop6h 21m
American Airlines
ven 4/104:33 pm
BTR
- TYS
1 stop4h 51m
American Airlines
Deal found 3/13![American Airlines logo]()
$309
This Southwest deal was found by Cheapflights users on 3/16. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
sab 4/116:40 am
TYS
- MSY
1 stop3h 35m
Southwest
mar 4/148:25 am
MSY
- TYS
1 stop4h 55m
Southwest
Deal found 3/16![Southwest logo]()
$309
This United Airlines deal was found by Cheapflights users on 3/16. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
mer 4/227:05 am
TYS
- BTR
1 stop7h 20m
United Airlines
sab 4/2512:00 pm
BTR
- TYS
1 stop6h 56m
United Airlines
Deal found 3/16![United Airlines logo]()
$329
This Delta deal was found by Cheapflights users on 3/16. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
ven 4/247:00 pm
TYS
- AEX
1 stop3h 43m
Delta
dom 4/266:08 am
AEX
- TYS
1 stop4h 09m
Delta
Deal found 3/16![Delta logo]()
$338
This American Airlines deal was found by Cheapflights users on 3/14. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
ven 5/14:09 pm
TYS
- BTR
1 stop7h 37m
American Airlines
dom 5/35:40 am
BTR
- TYS
1 stop5h 50m
American Airlines
Deal found 3/14![American Airlines logo]()
$309
This Southwest deal was found by Cheapflights users on 3/13. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
sab 4/117:45 am
TYS
- MSY
2 stops12h 10m
Southwest
sab 4/188:30 am
MSY
- TYS
2 stops9h 00m
Southwest
Deal found 3/13![Southwest logo]()
$325
This American Airlines deal was found by Cheapflights users on 3/16. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
mar 3/318:50 am
TYS
- BTR
1 stop5h 01m
American Airlines
sab 4/45:00 am
BTR
- TYS
1 stop5h 30m
American Airlines
Deal found 3/16![American Airlines logo]()
$319
This United Airlines deal was found by Cheapflights users on 3/15. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
mar 8/253:25 pm
TYS
- AEX
1 stop5h 13m
United Airlines
sab 8/294:05 pm
AEX
- TYS
1 stop4h 25m
United Airlines
Deal found 3/15![United Airlines logo]()
$358
This Southwest deal was found by Cheapflights users on 3/13. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
ven 4/176:45 pm
TYS
- MSY
2 stops5h 50m
Southwest
mar 4/2110:35 am
MSY
- TYS
2 stops8h 05m
Southwest
Deal found 3/13![Southwest logo]()
$337
This United Airlines deal was found by Cheapflights users on 3/17. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
mar 8/187:15 am
TYS
- LFT
1 stop5h 00m
United Airlines
sab 8/225:25 am
LFT
- TYS
1 stop4h 52m
United Airlines
Deal found 3/17![United Airlines logo]()
$381
This Delta deal was found by Cheapflights users on 3/17. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
ven 6/125:30 am
TYS
- BTR
1 stop5h 04m
Delta
lun 6/153:20 pm
BTR
- TYS
1 stop5h 24m
Delta
Deal found 3/17![Delta logo]()
$424
This Southwest deal was found by Cheapflights users on 3/14. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
gio 5/76:35 am
TYS
- MSY
2 stops8h 35m
Southwest
dom 5/105:20 am
MSY
- TYS
1 stop8h 55m
Southwest
Deal found 3/14![Southwest logo]()
$354
This American Airlines deal was found by Cheapflights users on 3/13. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
sab 3/285:00 am
TYS
- BTR
2 stops9h 46m
American Airlines
mer 4/15:00 am
BTR
- TYS
1 stop5h 30m
American Airlines
Deal found 3/13![American Airlines logo]()
$402
This United Airlines deal was found by Cheapflights users on 3/17. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
sab 5/97:00 am
TYS
- MSY
1 stop7h 09m
United Airlines
mer 5/1312:13 pm
MSY
- TYS
1 stop7h 32m
United Airlines
Deal found 3/17![United Airlines logo]()
$412
This Southwest deal was found by Cheapflights users on 3/16. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
mar 6/167:10 am
TYS
- MSY
1 stop3h 30m
Southwest
ven 6/191:45 pm
MSY
- TYS
2 stops6h 25m
Southwest
Deal found 3/16![Southwest logo]()
$382
This American Airlines deal was found by Cheapflights users on 3/13. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
gio 4/304:09 pm
TYS
- LFT
1 stop7h 50m
American Airlines
lun 5/45:07 pm
LFT
- TYS
1 stop5h 49m
American Airlines
Deal found 3/13![American Airlines logo]()
$423
This Southwest deal was found by Cheapflights users on 3/17. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
ven 4/246:35 am
TYS
- MSY
2 stops8h 35m
Southwest
dom 5/35:30 am
MSY
- TYS
2 stops7h 35m
Southwest
Deal found 3/17![Southwest logo]()
$387
This American Airlines deal was found by Cheapflights users on 3/14. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
gio 4/166:00 am
TYS
- LFT
1 stop5h 12m
American Airlines
dom 4/195:42 am
LFT
- TYS
1 stop5h 48m
American Airlines
Deal found 3/14![American Airlines logo]()
$423
This Southwest deal was found by Cheapflights users on 3/15. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
ven 4/246:35 am
TYS
- MSY
2 stops8h 35m
Southwest
lun 4/275:50 am
MSY
- TYS
2 stops7h 20m
Southwest
Deal found 3/15![Southwest logo]()
$393
This American Airlines deal was found by Cheapflights users on 3/18. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
ven 5/297:01 am
TYS
- LFT
1 stop7h 21m
American Airlines
dom 5/315:30 pm
LFT
- TYS
1 stop5h 23m
American Airlines
Deal found 3/18![American Airlines logo]()
$428
This Southwest deal was found by Cheapflights users on 3/13. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
gio 5/216:35 am
TYS
- MSY
2 stops6h 10m
Southwest
lun 5/255:50 am
MSY
- TYS
2 stops7h 20m
Southwest
Deal found 3/13![Southwest logo]()
$393
This United Airlines deal was found by Cheapflights users on 3/13. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
ven 4/311:25 am
TYS
- BTR
1 stop7h 08m
United Airlines
ven 4/106:08 pm
BTR
- TYS
2 stops27h 26m
United Airlines
Deal found 3/13![United Airlines logo]()
$533
This American Airlines deal was found by Cheapflights users on 3/17. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
ven 4/36:21 pm
TYS
- AEX
1 stop5h 43m
American Airlines
dom 4/56:00 am
AEX
- TYS
1 stop4h 30m
American Airlines
Deal found 3/17![American Airlines logo]()
$456
This American Airlines deal was found by Cheapflights users on 3/14. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
ven 4/248:00 am
TYS
- AEX
2 stops10h 56m
American Airlines
dom 4/266:26 pm
AEX
- TYS
1 stop4h 30m
American Airlines
Deal found 3/14![American Airlines logo]()
$532
This American Airlines deal was found by Cheapflights users on 3/18. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
ven 7/175:36 am
TYS
- BTR
1 stop6h 22m
American Airlines
lun 7/202:19 pm
BTR
- TYS
1 stop6h 40m
American Airlines
Deal found 3/18![American Airlines logo]()
$533
Last-minute flights from Knoxville to LouisianaDiscover last-minute flight deals from Knoxville to Louisiana. Data last updated marzo 18, 2026 and is based on user searches.
Discover last-minute flight deals from Knoxville to Louisiana. Data last updated marzo 18, 2026 and is based on user searches.
This Kiwi.com deal was found by Cheapflights users on 3/13. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
gio 3/267:50 pm
TYS
- MSY
1 stop21h 36m
Multiple Airlines
sab 3/286:00 am
MSY
- TYS
1 stop13h 51m
Multiple Airlines
Deal found 3/13![Multiple Airlines logo]()
$247
This American Airlines deal was found by Cheapflights users on 3/13. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
sab 3/289:25 am
TYS
- BTR
1 stop7h 36m
American Airlines
mer 4/15:57 pm
BTR
- TYS
1 stop4h 54m
American Airlines
Deal found 3/13![American Airlines logo]()
$319
This Kiwi.com deal was found by Cheapflights users on 3/16. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
lun 3/306:20 am
TYS
- MSY
1 stop11h 06m
Multiple Airlines
mar 3/317:10 pm
MSY
- TYS
1 stop14h 26m
Multiple Airlines
Deal found 3/16![Multiple Airlines logo]()
$237
This American Airlines deal was found by Cheapflights users on 3/16. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
mar 3/316:31 pm
TYS
- LFT
1 stop5h 27m
American Airlines
sab 4/46:16 pm
LFT
- TYS
1 stop4h 35m
American Airlines
Deal found 3/16![American Airlines logo]()
$319
This Kiwi.com deal was found by Cheapflights users on 3/15. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
mer 4/18:30 am
TYS
- MSY
1 stop27h 59m
Multiple Airlines
sab 4/47:18 pm
MSY
- TYS
1 stop27h 21m
Multiple Airlines
Deal found 3/15![Multiple Airlines logo]()
$252
This American Airlines deal was found by Cheapflights users on 3/13. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
ven 4/34:15 pm
TYS
- BTR
1 stop6h 21m
American Airlines
ven 4/104:33 pm
BTR
- TYS
1 stop4h 51m
American Airlines
Deal found 3/13![American Airlines logo]()
$309
This Kiwi.com deal was found by Cheapflights users on 3/16. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
sab 4/410:00 am
TYS
- MSY
1 stop9h 55m
Multiple Airlines
mar 4/77:18 pm
MSY
- TYS
1 stop14h 18m
Multiple Airlines
Deal found 3/16![Multiple Airlines logo]()
$206
This Kiwi.com deal was found by Cheapflights users on 3/14. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
sab 4/119:00 am
TYS
- MSY
1 stop10h 55m
Multiple Airlines
lun 4/134:38 pm
MSY
- TYS
1 stop21h 20m
Multiple Airlines
Deal found 3/14![Multiple Airlines logo]()
$211
This Kiwi.com deal was found by Cheapflights users on 3/13. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
sab 4/119:00 am
TYS
- MSY
1 stop10h 23m
Multiple Airlines
sab 4/185:15 am
MSY
- TYS
1 stop5h 51m
Multiple Airlines
Deal found 3/13![Multiple Airlines logo]()
$236
This Kiwi.com deal was found by Cheapflights users on 3/16. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
ven 4/175:39 pm
TYS
- MSY
1 stop26h 16m
Multiple Airlines
gio 4/236:32 pm
MSY
- TYS
2 stops26h 16m
Multiple Airlines
Deal found 3/16![Multiple Airlines logo]()
$215
This Kiwi.com deal was found by Cheapflights users on 3/13. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
ven 4/175:39 pm
TYS
- MSY
1 stop26h 16m
Multiple Airlines
mar 4/213:39 pm
MSY
- TYS
1 stop17h 57m
Multiple Airlines
Deal found 3/13![Multiple Airlines logo]()
$242
This Kiwi.com deal was found by Cheapflights users on 3/17. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
dom 4/199:12 pm
TYS
- MSY
1 stop19h 37m
Multiple Airlines
gio 4/235:15 am
MSY
- TYS
1 stop14h 27m
Multiple Airlines
Deal found 3/17![Multiple Airlines logo]()
$216
One-way flights from Knoxville to LouisianaSearch for one-way flight options from Knoxville to Louisiana. Find affordable one-way fares based on user searches. Data last updated marzo 18, 2026.
Search for one-way flight options from Knoxville to Louisiana. Find affordable one-way fares based on user searches. Data last updated marzo 18, 2026.
This Kiwi.com deal was found by Cheapflights users on 3/15. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
dom 4/129:12 pm
TYS
- MSY
1 stop19h 36m
Allegiant Air
Deal found 3/15![Allegiant Air logo]()
$102
This Trip.com deal was found by Cheapflights users on 3/15. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Trip.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
mer 4/154:25 pm
TYS
- MSY
1 stop8h 05m
Multiple Airlines
Deal found 3/15![Multiple Airlines logo]()
$104
This Kiwi.com deal was found by Cheapflights users on 3/13. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
ven 4/105:39 pm
TYS
- MSY
1 stop26h 16m
Multiple Airlines
Deal found 3/13![Multiple Airlines logo]()
$107
This Kiwi.com deal was found by Cheapflights users on 3/17. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
mer 4/18:30 am
TYS
- MSY
1 stop24h 16m
Multiple Airlines
Deal found 3/17![Multiple Airlines logo]()
$111
This Kiwi.com deal was found by Cheapflights users on 3/13. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
mer 4/84:25 pm
TYS
- MSY
1 stop7h 19m
Multiple Airlines
Deal found 3/13![Multiple Airlines logo]()
$112
This Trip.com deal was found by Cheapflights users on 3/13. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Trip.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
dom 3/299:13 pm
TYS
- MSY
1 stop20h 13m
Allegiant Air
Deal found 3/13![Allegiant Air logo]()
$118
This Kiwi.com deal was found by Cheapflights users on 3/17. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
lun 4/137:30 am
TYS
- MSY
1 stop25h 49m
Multiple Airlines
Deal found 3/17![Multiple Airlines logo]()
$121
This Kiwi.com deal was found by Cheapflights users on 3/17. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
ven 5/151:15 pm
TYS
- MSY
2 stops28h 06m
Multiple Airlines
Deal found 3/17![Multiple Airlines logo]()
$123
This American Airlines deal was found by Cheapflights users on 3/13. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
dom 5/36:00 am
TYS
- LFT
1 stop5h 12m
American Airlines
Deal found 3/13![American Airlines logo]()
$269
This Delta deal was found by Cheapflights users on 3/17. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
dom 9/137:20 pm
TYS
- LFT
1 stop3h 39m
Delta
Deal found 3/17![Delta logo]()
$279
This Delta deal was found by Cheapflights users on 3/13. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
dom 5/35:40 am
TYS
- BTR
1 stop5h 06m
Delta
Deal found 3/13![Delta logo]()
$280
This American Airlines deal was found by Cheapflights users on 3/15. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
dom 9/136:00 am
TYS
- LFT
1 stop5h 32m
American Airlines
Deal found 3/15![American Airlines logo]()
$289
Find flight deals from Knoxville to Louisiana
Keep the following information in mind while searching for Knoxville to Louisiana flight deals. Data was last updated marzo 18, 2026.
Most accurate provider | FlightHub 3 stars |
|---|---|
Most trusted provider | FlightHub 3 stars |
Round-trip from | $206 (Kiwi.com) |
One-way from | $102 (Kiwi.com) |
Popular in | February |
Cheapest in | August |
Average price | $424 |
Cheapflights Fare Finder
Customize your flight search to find flights from Knoxville to Louisiana that fit within your specific budget. Explore options based on user searches and filter the results based on your desired price range. Find flights that match your budget for a cost-effective journey. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated marzo 18, 2026.
Use the filters below to find and compare flights from Knoxville to Louisiana that are best for you.
Fly from
Fly to
Route
Depart
Return
Cheapest round-trip
KnoxvilleBaton Rouge
TYS - BTR
TYSBTR
Knoxville McGhee Tyson
ven 4/3
4:15 pm-9:36 pm
1 stop6h 21m
Baton Rouge Ryan
ven 4/10
4:33 pm-10:24 pm
1 stop4h 51m
$309
KnoxvilleNew Orleans
TYS - MSY
TYSMSY
Knoxville McGhee Tyson
sab 4/11
6:40 am-9:15 am
1 stop3h 35m
New Orleans Louis Armstrong
mar 4/14
8:25 am-2:20 pm
1 stop4h 55m
$309
KnoxvilleBaton Rouge
TYS - BTR
TYSBTR
Knoxville McGhee Tyson
ven 5/1
4:09 pm-10:46 pm
1 stop7h 37m
Baton Rouge Ryan
dom 5/3
5:40 am-12:30 pm
1 stop5h 50m
$309
KnoxvilleBaton Rouge
TYS - BTR
TYSBTR
Knoxville McGhee Tyson
mar 3/31
8:50 am-12:51 pm
1 stop5h 01m
Baton Rouge Ryan
sab 4/4
5:00 am-11:30 am
1 stop5h 30m
$319
KnoxvilleNew Orleans
TYS - MSY
TYSMSY
Knoxville McGhee Tyson
sab 4/11
7:45 am-6:55 pm
2 stops12h 10m
New Orleans Louis Armstrong
sab 4/18
8:30 am-6:30 pm
2 stops9h 00m
$325
KnoxvilleBaton Rouge
TYS - BTR
TYSBTR
Knoxville McGhee Tyson
mer 4/22
7:05 am-1:25 pm
1 stop7h 20m
Baton Rouge Ryan
sab 4/25
12:00 pm-7:56 pm
1 stop6h 56m
$329
KnoxvilleNew Orleans
TYS - MSY
TYSMSY
Knoxville McGhee Tyson
ven 4/17
6:45 pm-11:35 pm
2 stops5h 50m
New Orleans Louis Armstrong
mar 4/21
10:35 am-7:40 pm
2 stops8h 05m
$337
Quickest round-trip
KnoxvilleAlexandria
TYS - AEX
TYSAEX
Knoxville McGhee Tyson
ven 4/24
7:00 pm-9:43 pm
1 stop3h 43m
Alexandria
dom 4/26
6:08 am-11:17 am
1 stop4h 09m
$338
KnoxvilleNew Orleans
TYS - MSY
TYSMSY
Knoxville McGhee Tyson
gio 5/7
6:35 am-2:10 pm
2 stops8h 35m
New Orleans Louis Armstrong
dom 5/10
5:20 am-3:15 pm
1 stop8h 55m
$354
KnoxvilleAlexandria
TYS - AEX
TYSAEX
Knoxville McGhee Tyson
mar 8/25
3:25 pm-7:38 pm
1 stop5h 13m
Alexandria
sab 8/29
4:05 pm-9:30 pm
1 stop4h 25m
$358
Showing 1-10 of 41 resultsSorted by cheapest first
Best time to book a flight from Knoxville to Louisiana
Have a flexible travel schedule? Discover the best time to fly to Louisiana from Knoxville with our price prediction graph.
TYS-MSY
TYS-LFT
TYS-BTR
TYS-AEX
Estimated round-trip price
Rates are based on past data. Find the cheapest month and day to book your flight based on your travel requirements, then search for cheap deals.
Cheapflights Insights
Everything you need to know about your flight from Knoxville to Louisiana
TYS-USLA
TYS-MSY
TYS-LFT
TYS-BTR
TYS-AEX
What is the cheapest month to book a flight from Knoxville to Louisiana?
Currently, August is the cheapest month in which you can book a flight from Knoxville to Louisiana (average of $156). Flying from Knoxville to Louisiana in February is currently the most expensive (average of $269). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.
Reviews of airlines servicing Louisiana
Get insights into the airlines that provide service to Louisiana. Read reviews, discover amenities, and learn about the overall travel experience offered by airlines. Use this information to make informed decisions when choosing an airline for your flight to Louisiana. Reviews last updated marzo 18, 2026.
See what other customers who have flown with Southwest,Delta, andAmerican Airlines from Knoxville to Louisiana have to say. Users can see the overall rating for each airline as well as how each is rated in terms of entertainment options, comfort, food, crew/service, and boarding process.
Crew
8.6
Comfort
8.0
Boarding
8.1
Entertainment
7.5
Overall
8.0
Food
7.0
Reviews
1 / 20
10.0
ExcellentAnonymous,Mar 2026
KOA - HNL
Crew
8.6
Comfort
8.0
Boarding
8.1
Entertainment
7.5
Overall
8.0
Food
7.0
Reviews
1 / 20
10.0
ExcellentAnonymous,Mar 2026
KOA - HNL
Crew
8.6
Comfort
8.0
Boarding
8.1
Entertainment
7.5
Overall
8.0
Food
7.0
Reviews
1 / 20
10.0
ExcellentAnonymous,Mar 2026
KOA - HNL
Crew
8.6
Comfort
8.0
Boarding
8.1
Entertainment
7.5
Overall
8.0
Food
7.0
Reviews
1 / 20
10.0
ExcellentAnonymous,Mar 2026
KOA - HNL
Related info for your journey
Find useful and relevant information for your journey from Knoxville to Louisiana. Access travel guides, tips, and recommendations to enhance your travel experience. Get information about local attractions, weather, transportation options, and more.
Browse thousands of different options on Cheapflights for your next trip
Toggle through the tabs below to find thousands of options on Cheapflights for your next trip.
Alternative routes
Complete your trip
Flights by cabin class
Other flight options
Popular flights
Top destinations
Alternative routes for Knoxville to Louisiana
See prices for flight routes from nearby airports that may be better suited for you.
Complete your trip
Complete your trip to Louisiana by adding a car rental and/or hotel reservation to your travel itinerary.
Search flights from Knoxville to Louisiana by cabin class
Find flights from Knoxville to Louisiana, based on your preferred cabin class, be it economy, premium economy, business, or first class.
Knoxville and Louisiana flights
Browse other Knoxville and Louisiana flight options. Last updated on marzo 18, 2026.
Popular flight searches
Check out other popular destinations found by fellow travelers in 2026
Knoxville to Louisiana flights
Consider these flights traveling from Knoxville to Louisiana.
Top 3 airlines flying from Knoxville to Louisiana
Discover the top 3 airlines that operate flights from Knoxville to Louisiana. Compare their services, reliability, and customer satisfaction ratings to choose the airline that best suits your travel preferences and needs. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated marzo 18, 2026.
| Airline | Cheapest | Average | Flexibility | On-time |
|---|---|---|---|---|
| Cheapest$223 | Average$381 | FlexibilityNo cancel fee | On-time71% | |
| Cheapest$248 | Average$428 | FlexibilityNo cancel fee | On-timeN/A | |
| Cheapest$306 | Average$363 | FlexibilityNo cancel fee | On-time63% |