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$91+ Cheap flights from Knoxville (TYS) to Louisiana

This is the cheapest one-way flight price found by a Cheapflights user in the last 72 hours by searching for a flight departing on 8/25. Fares are subject to change and may not be available on all flights or dates of travel.
TYS — MSY
Aug 3 — Aug 101
Sun 8/3
Sun 8/10
1 adult, Economy
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Cheap flight deals from Knoxville to Louisiana

Keep the following information in mind while searching for Knoxville to Louisiana flight deals. Data was last updated July 29, 2025.

Round-trip from

$189
(Mytrip)

One-way from

$91
(Mytrip)

Popular in

March

Cheapest in

August

Average price

$373
From Knoxville McGhee Tyson to Louisiana
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One-way flight from Knoxville McGhee Tyson to Louisiana
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Highest demand for flights based on searches. 16% potential increase in price ($74 potential increase over avg. RT price).
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Cheapest flight prices on average. 2% potential price decrease ($9 potential savings vs. average RT price).
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Average for round-trip flights in July 2025
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Find flight deals from Knoxville to Louisiana

Cheapest flights from Knoxville to Louisiana
Explore the most affordable flight options available from Knoxville to Louisiana. Find the lowest fares from popular airlines and budget airlines, with prices last updated on July 29, 2025.

This Mytrip deal was found by Cheapflights users on 7/28. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Mytrip is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 8/221:22 pmTYS - MSY
1 stop10h 06mMultiple Airlines
Mon 8/255:20 amMSY - TYS
1 stop11h 18mMultiple Airlines
Deal found 7/28$189
This American Airlines deal was found by Cheapflights users on 7/28. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 8/3012:20 pmTYS - MSY
1 stop6h 03mAmerican Airlines
Sat 9/65:18 pmMSY - TYS
1 stop5h 32mAmerican Airlines
Deal found 7/28$224
This Delta deal was found by Cheapflights users on 7/28. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 9/267:11 pmTYS - BTR
1 stop4h 01mDelta
Tue 9/306:20 amBTR - TYS
1 stop5h 47mDelta
Deal found 7/28$249
This Delta deal was found by Cheapflights users on 7/29. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 9/126:08 pmTYS - MSY
1 stop5h 05mDelta
Tue 9/163:10 pmMSY - TYS
1 stop3h 52mDelta
Deal found 7/29$249
This United Airlines deal was found by Cheapflights users on 7/29. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 7/305:00 pmTYS - BTR
1 stop7h 24mUnited Airlines
Sun 8/315:00 amBTR - TYS
1 stop7h 38mUnited Airlines
Deal found 7/29$294
This American Airlines deal was found by Cheapflights users on 7/27. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 9/266:00 amTYS - BTR
1 stop4h 38mAmerican Airlines
Tue 9/3010:08 amBTR - TYS
2 stops7h 42mAmerican Airlines
Deal found 7/27$298
This United Airlines deal was found by Cheapflights users on 7/28. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 7/317:00 amTYS - MSY
1 stop7h 20mUnited Airlines
Sat 8/212:42 pmMSY - TYS
1 stop7h 15mUnited Airlines
Deal found 7/28$339
This American Airlines deal was found by Cheapflights users on 7/29. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 7/306:00 amTYS - AEX
1 stop5h 31mAmerican Airlines
Sat 8/25:52 amAEX - TYS
1 stop4h 49mAmerican Airlines
Deal found 7/29$384
This American Airlines deal was found by Cheapflights users on 7/26. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 10/106:00 amTYS - LFT
1 stop4h 35mAmerican Airlines
Sun 10/1910:05 amLFT - TYS
1 stop6h 27mAmerican Airlines
Deal found 7/26$428

Cheapflights Fare Finder

 
Customize your flight search to find flights from Knoxville to Louisiana that fit within your specific budget. Explore options based on user searches and filter the results based on your desired price range. Find flights that match your budget for a cost-effective journey. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated July 29, 2025.
Use the filters below to find and compare flights from Knoxville to Louisiana that are best for you.

Fly from

Knoxville

Fly to

Louisiana

Route

Depart

Return

Price

KnoxvilleNew Orleans

TYS - MSY

TYSMSY

Knoxville McGhee Tyson

Fri 8/22

1:22 pm-10:28 pm

1 stop10h 06m

New Orleans Louis Armstrong

Mon 8/25

5:20 am-5:38 pm

1 stop11h 18m

$189

KnoxvilleNew Orleans

TYS - MSY

TYSMSY

Knoxville McGhee Tyson

Sat 8/30

12:20 pm-5:23 pm

1 stop6h 03m

New Orleans Louis Armstrong

Sat 9/6

5:18 pm-11:50 pm

1 stop5h 32m

$224

KnoxvilleBaton Rouge

TYS - BTR

TYSBTR

Knoxville McGhee Tyson

Fri 9/26

7:11 pm-10:12 pm

1 stop4h 01m

Baton Rouge Ryan

Tue 9/30

6:20 am-1:07 pm

1 stop5h 47m

$249

KnoxvilleNew Orleans

TYS - MSY

TYSMSY

Knoxville McGhee Tyson

Fri 9/12

6:08 pm-10:13 pm

1 stop5h 05m

New Orleans Louis Armstrong

Tue 9/16

3:10 pm-8:02 pm

1 stop3h 52m

$249

KnoxvilleBaton Rouge

TYS - BTR

TYSBTR

Knoxville McGhee Tyson

Fri 8/29

8:25 pm-11:39 pm

1 stop4h 14m

Baton Rouge Ryan

Sun 8/31

5:45 am-3:35 pm

2 stops8h 50m

$254

KnoxvilleNew Orleans

TYS - MSY

TYSMSY

Knoxville McGhee Tyson

Sat 8/23

7:00 am-7:55 pm

2 stops13h 55m

New Orleans Louis Armstrong

Wed 8/27

2:20 pm-10:37 pm

1 stop7h 17m

$377

KnoxvilleLafayette

TYS - LFT

TYSLFT

Knoxville McGhee Tyson

Fri 10/10

6:00 am-9:35 am

1 stop4h 35m

Lafayette Regional

Sun 10/19

10:05 am-5:32 pm

1 stop6h 27m

$428

KnoxvilleBaton Rouge

TYS - BTR

TYSBTR

Knoxville McGhee Tyson

Fri 9/12

7:00 am-11:11 am

2 stops29h 11m

Baton Rouge Ryan

Tue 9/16

3:52 pm-11:44 pm

1 stop6h 52m

$463

KnoxvilleNew Orleans

TYS - MSY

TYSMSY

Knoxville McGhee Tyson

Mon 8/25

1:22 pm-10:28 pm

1 stop10h 06m

$91

KnoxvilleBaton Rouge

TYS - BTR

TYSBTR

Knoxville McGhee Tyson

Fri 9/19

12:01 pm-3:52 pm

1 stop4h 51m

$155

Flights are sorted by cheapest round-trip flights first.

Deals found on 7/26

Showing 1-10 of 17 results
1
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Best time to book a flight from Knoxville to Louisiana

Have a flexible travel schedule? Discover the best time to fly to Louisiana from Knoxville with our price prediction graph.
Estimated round-trip price
Rates are based on past data. Find the cheapest month and day to book your flight based on your travel requirements, then search for cheap deals.

Cheapflights Insights

Everything you need to know about your flight from Knoxville to Louisiana

What is the cheapest month to book a flight from Knoxville to Louisiana?

Currently, August is the cheapest month in which you can book a flight from Knoxville to Louisiana (average of $256). Flying from Knoxville to Louisiana in April is currently the most expensive (average of $343). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.

What is the cheapest time of day to fly from TYS to LA?

Find hourly flight availability from Knoxville to Louisiana. Discover flight options and departure times throughout the day, allowing you to choose a departure time that suits your schedule. Data last updated July 29, 2025.

When flying from Knoxville to Louisiana, the time of day you decide to fly out makes little to no difference towards the overall price you’ll pay on tickets.

Reviews of airlines servicing Louisiana

Get insights into the airlines that provide service to Louisiana. Read reviews, discover amenities, and learn about the overall travel experience offered by airlines. Use this information to make informed decisions when choosing an airline for your flight to Louisiana. Reviews last updated July 29, 2025.
See what other customers who have flown with Delta, United Airlines, and American Airlines from Knoxville to Louisiana have to say. Users can see the overall rating for each airline as well as how each is rated in terms of entertainment options, comfort, food, crew/service, and boarding process.
Delta
8.0
Very good
7,977 reviews

Comfort

7.9

Crew

8.5

Boarding

8.2

Entertainment

7.9

Food

7.3

Overall

8.0

Reviews

1 / 20
10.0
Excellent

Kim,May 2025

PIH - SLC

This trip was fine even with delay I had plenty of time to get connection flight!
Delta
8.0
Very good
7,977 reviews
Delta
8.0
Very good
7,977 reviews

Comfort

7.9

Crew

8.5

Boarding

8.2

Entertainment

7.9

Food

7.3

Overall

8.0

Reviews

1 / 20
10.0
Excellent

Kim,May 2025

PIH - SLC

This trip was fine even with delay I had plenty of time to get connection flight!
United Airlines
7.4
Good
8,899 reviews
Delta
8.0
Very good
7,977 reviews

Comfort

7.9

Crew

8.5

Boarding

8.2

Entertainment

7.9

Food

7.3

Overall

8.0

Reviews

1 / 20
10.0
Excellent

Kim,May 2025

PIH - SLC

This trip was fine even with delay I had plenty of time to get connection flight!
American Airlines
7.2
Good
10,000 reviews
Delta
8.0
Very good
7,977 reviews

Comfort

7.9

Crew

8.5

Boarding

8.2

Entertainment

7.9

Food

7.3

Overall

8.0

Reviews

1 / 20
10.0
Excellent

Kim,May 2025

PIH - SLC

This trip was fine even with delay I had plenty of time to get connection flight!

Related info for your journey

Find useful and relevant information for your journey from Knoxville to Louisiana. Access travel guides, tips, and recommendations to enhance your travel experience. Get information about local attractions, weather, transportation options, and more.

  • What airport do you fly from for flights from Knoxville to Louisiana?

    Located just 11.3 mi from the city center, Knoxville McGhee Tyson (TYS) is the airport most travelers will use when flying to Louisiana from Knoxville.

  • What are the cheapest airlines to fly from Knoxville to Louisiana one-way?

    $155 is the cheapest one-way deal found within the past few days, from Delta. You may also be able to find cheap deals on American Airlines and United Airlines, with prices starting from $239 and $357, respectively.

  • What are the most popular routes from Knoxville to Louisiana?

    The most popular flight routes from Knoxville to Louisiana are Knoxville McGhee Tyson - New Orleans Louis Armstrong, Knoxville McGhee Tyson - Baton Rouge Ryan and Knoxville McGhee Tyson - Lafayette Regional.

  • Can I find deals for flights from Knoxville to Louisiana that include hotel bookings?

    Yes. In addition to deals on Knoxville to Louisiana flights, Cheapflights offers vacation packages that include both flights and hotel.

  • How can I find direct flights from Knoxville to Louisiana?

    After entering your origin and destination, apply the non-stop filter on the search result page to find direct flights from Knoxville to Louisiana.

  • Can I find deals for business class flights from Knoxville to Louisiana?

    Yes. Cheapflights offers flight deals from Knoxville to Louisiana by cabin class. In addition to browsing deals, you can also filter by cabin class on the search results page after making a search.

  • What is the cheapest month to book a flight from Knoxville to Louisiana?

    Currently, August is the cheapest month in which you can book a flight from Knoxville to Louisiana (average of $256). Flying from Knoxville to Louisiana in April is currently the most expensive (average of $343). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.

See more FAQs

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Top 3 airlines flying from Knoxville to Louisiana

Discover the top 3 airlines that operate flights from Knoxville to Louisiana. Compare their services, reliability, and customer satisfaction ratings to choose the airline that best suits your travel preferences and needs. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated July 29, 2025.
AirlineCheapestAverageFlexibilityOn-time
DeltaCheapest$171Average$339FlexibilityNo cancel feeOn-timeN/A
American AirlinesCheapest$208Average$405FlexibilityNo cancel feeOn-time71%
United AirlinesCheapest$253Average$408FlexibilityNo cancel feeOn-time69%

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