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$99+ Cheap flights from Knoxville (TYS) to Louisiana

This is the cheapest one-way flight price found by a Cheapflights user in the last 72 hours by searching for a flight departing on 7/21. Fares are subject to change and may not be available on all flights or dates of travel.
TYS — MSY
Jun 17 — Jun 241
Tue 6/17
Tue 6/24
1 adult, Economy
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Cheap flight deals from Knoxville to Louisiana

Keep the following information in mind while searching for Knoxville to Louisiana flight deals. Data was last updated June 12, 2025.

Round-trip from

$198
(Mytrip)

One-way from

$99
(Mytrip)

Popular in

November

Cheapest in

September

Average price

$343
From Knoxville McGhee Tyson to Louisiana
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One-way flight from Knoxville McGhee Tyson to Louisiana
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Highest demand for flights based on searches. 9% potential increase in price ($40 potential increase over avg. RT price).
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Cheapest flight prices on average. 2% potential price decrease ($9 potential savings vs. average RT price).
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Average for round-trip flights in June 2025
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Find flight deals from Knoxville to Louisiana

Cheapest flights from Knoxville to Louisiana
Explore the most affordable flight options available from Knoxville to Louisiana. Find the lowest fares from popular airlines and budget airlines, with prices last updated on June 12, 2025.

This Mytrip deal was found by Cheapflights users on 6/11. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Mytrip is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 8/156:00 amTYS - MSY
1 stop26h 02mMultiple Airlines
Thu 8/211:40 pmMSY - TYS
1 stop26h 58mMultiple Airlines
Deal found 6/11$198
This American Airlines deal was found by Cheapflights users on 6/11. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 7/22:16 pmTYS - MSY
1 stop5h 45mAmerican Airlines
Sat 7/126:16 pmMSY - TYS
1 stop4h 36mAmerican Airlines
Deal found 6/11$224
This American Airlines deal was found by Cheapflights users on 6/12. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 7/185:19 pmTYS - BTR
1 stop5h 47mAmerican Airlines
Tue 7/224:13 pmBTR - TYS
1 stop6h 39mAmerican Airlines
Deal found 6/12$249
This Delta deal was found by Cheapflights users on 6/11. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 7/112:36 pmTYS - MSY
1 stop4h 40mDelta
Tue 7/151:05 pmMSY - TYS
1 stop3h 07mDelta
Deal found 6/11$249
This United Airlines deal was found by Cheapflights users on 6/11. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 6/265:45 amTYS - MSY
1 stop5h 28mUnited Airlines
Mon 6/308:00 amMSY - TYS
1 stop5h 58mUnited Airlines
Deal found 6/11$284
This Delta deal was found by Cheapflights users on 6/10. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 7/1010:59 amTYS - LFT
1 stop4h 55mDelta
Thu 7/175:39 pmLFT - TYS
1 stop5h 20mDelta
Deal found 6/10$339
This American Airlines deal was found by Cheapflights users on 6/11. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 6/265:15 amTYS - LFT
1 stop5h 56mAmerican Airlines
Mon 6/306:54 amLFT - TYS
1 stop6h 26mAmerican Airlines
Deal found 6/11$377
This Delta deal was found by Cheapflights users on 6/12. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 6/155:45 amTYS - BTR
1 stop4h 12mDelta
Mon 6/167:03 pmBTR - TYS
1 stop3h 56mDelta
Deal found 6/12$399
This American Airlines deal was found by Cheapflights users on 6/10. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 10/236:31 pmTYS - AEX
1 stop4h 36mAmerican Airlines
Mon 10/276:23 pmAEX - TYS
1 stop4h 24mAmerican Airlines
Deal found 6/10$404
This United Airlines deal was found by Cheapflights users on 6/12. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 7/185:46 pmTYS - BTR
2 stops16h 13mUnited Airlines
Mon 7/214:02 pmBTR - TYS
1 stop6h 25mUnited Airlines
Deal found 6/12$458
This United Airlines deal was found by Cheapflights users on 6/10. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 7/105:46 pmTYS - LFT
2 stops24h 55mUnited Airlines
Thu 7/174:10 pmLFT - TYS
2 stops29h 27mUnited Airlines
Deal found 6/10$674

Cheapflights Fare Finder

Customize your flight search to find flights from Knoxville to Louisiana that fit within your specific budget. Explore options based on user searches and filter the results based on your desired price range. Find flights that match your budget for a cost-effective journey. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated June 12, 2025.
Use the filters below to find and compare flights from Knoxville to Louisiana that are best for you.

Fly from

Knoxville

Fly to

Louisiana

Route

Depart

Return

Price

KnoxvilleNew Orleans

TYS - MSY

TYSMSY

Knoxville McGhee Tyson

Fri 8/15

6:00 am-7:02 am

1 stop26h 02m

New Orleans Louis Armstrong

Thu 8/21

1:40 pm-5:38 pm

1 stop26h 58m

$198

KnoxvilleNew Orleans

TYS - MSY

TYSMSY

Knoxville McGhee Tyson

Wed 7/2

2:16 pm-7:01 pm

1 stop5h 45m

New Orleans Louis Armstrong

Sat 7/12

6:16 pm-11:52 pm

1 stop4h 36m

$224

KnoxvilleNew Orleans

TYS - MSY

TYSMSY

Knoxville McGhee Tyson

Fri 7/11

2:36 pm-6:16 pm

1 stop4h 40m

New Orleans Louis Armstrong

Tue 7/15

1:05 pm-5:12 pm

1 stop3h 07m

$249

KnoxvilleBaton Rouge

TYS - BTR

TYSBTR

Knoxville McGhee Tyson

Fri 7/18

5:19 pm-10:06 pm

1 stop5h 47m

Baton Rouge Ryan

Tue 7/22

4:13 pm-11:52 pm

1 stop6h 39m

$249

KnoxvilleNew Orleans

TYS - MSY

TYSMSY

Knoxville McGhee Tyson

Thu 6/26

5:45 am-10:13 am

1 stop5h 28m

New Orleans Louis Armstrong

Mon 6/30

8:00 am-2:58 pm

1 stop5h 58m

$284

KnoxvilleLafayette

TYS - LFT

TYSLFT

Knoxville McGhee Tyson

Thu 7/10

10:59 am-2:54 pm

1 stop4h 55m

Lafayette Regional

Thu 7/17

5:39 pm-11:59 pm

1 stop5h 20m

$339

KnoxvilleLafayette

TYS - LFT

TYSLFT

Knoxville McGhee Tyson

Thu 6/26

5:15 am-10:11 am

1 stop5h 56m

Lafayette Regional

Mon 6/30

6:54 am-2:20 pm

1 stop6h 26m

$377

KnoxvilleAlexandria

TYS - AEX

TYSAEX

Knoxville McGhee Tyson

Thu 10/23

6:31 pm-10:07 pm

1 stop4h 36m

Alexandria

Mon 10/27

6:23 pm-11:47 pm

1 stop4h 24m

$404

KnoxvilleBaton Rouge

TYS - BTR

TYSBTR

Knoxville McGhee Tyson

Thu 10/23

7:15 pm-10:00 pm

1 stop3h 45m

Baton Rouge Ryan

Sun 10/26

10:30 am-5:17 pm

1 stop5h 47m

$414

KnoxvilleBaton Rouge

TYS - BTR

TYSBTR

Knoxville McGhee Tyson

Fri 7/18

5:46 pm-8:59 am

2 stops16h 13m

Baton Rouge Ryan

Mon 7/21

4:02 pm-11:27 pm

1 stop6h 25m

$458

Flights are sorted by cheapest round-trip flights first.

Deals found on 6/10

Showing 1-10 of 20 results
1
2

Best time to book a flight from Knoxville to Louisiana

Have a flexible travel schedule? Discover the best time to fly to Louisiana from Knoxville with our price prediction graph.
Estimated round-trip price
Rates are based on past data. Find the cheapest month and day to book your flight based on your travel requirements, then search for cheap deals.

Cheapflights Insights

Everything you need to know about your flight from Knoxville to Louisiana

What is the cheapest month to book a flight from Knoxville to Louisiana?

Currently, August is the cheapest month in which you can book a flight from Knoxville to Louisiana (average of $256). Flying from Knoxville to Louisiana in April is currently the most expensive (average of $343). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.

What is the cheapest time of day to fly from TYS to LA?

Find hourly flight availability from Knoxville to Louisiana. Discover flight options and departure times throughout the day, allowing you to choose a departure time that suits your schedule. Data last updated June 12, 2025.

When flying from Knoxville to Louisiana, the time of day you decide to fly out makes little to no difference towards the overall price you’ll pay on tickets.

Rainfall in Louisiana by month

Plan your trip to Louisiana by taking into account the average rainfall totals by month.

In terms of precipitation, rainfall in Louisiana ranges from 3.3 - 6.4 inches per month. June is typically the wettest month, when rainfall can reach 6.4 in. October is typically the driest time to visit Louisiana when rainfall is around 3.3 in.

Temperature in Louisiana by month

Plan your trip to Louisiana by taking into account the average temperature totals by month.

If weather is an important factor for your trip to Louisiana, use this chart to help with planning. For those seeking warmer temperatures, July is the ideal time of year to visit, when temperatures reach an average of 82.4 F. Travelers looking to avoid the cold should look outside of January, when temperatures are typically at their lowest (around 51.8 F).

Reviews of airlines servicing Louisiana

Get insights into the airlines that provide service to Louisiana. Read reviews, discover amenities, and learn about the overall travel experience offered by airlines. Use this information to make informed decisions when choosing an airline for your flight to Louisiana. Reviews last updated June 12, 2025.
Read through reviews of airlines operating flights from Knoxville to Louisiana, such as Delta, United Airlines and American Airlines. Users can see the overall rating for each airline as well as how each is rated in terms of entertainment options, comfort, food, crew/service, and boarding process.
Delta
8.0
Very good
7,946 reviews

Food

7.3

Entertainment

7.9

Boarding

8.2

Overall

8.0

Comfort

7.9

Crew

8.5

Reviews

1 / 20
10.0
Excellent

Kim,May 2025

PIH - SLC

This trip was fine even with delay I had plenty of time to get connection flight!
Delta
8.0
Very good
7,946 reviews
Delta
8.0
Very good
7,946 reviews

Food

7.3

Entertainment

7.9

Boarding

8.2

Overall

8.0

Comfort

7.9

Crew

8.5

Reviews

1 / 20
10.0
Excellent

Kim,May 2025

PIH - SLC

This trip was fine even with delay I had plenty of time to get connection flight!
United Airlines
7.4
Good
8,790 reviews
Delta
8.0
Very good
7,946 reviews

Food

7.3

Entertainment

7.9

Boarding

8.2

Overall

8.0

Comfort

7.9

Crew

8.5

Reviews

1 / 20
10.0
Excellent

Kim,May 2025

PIH - SLC

This trip was fine even with delay I had plenty of time to get connection flight!
American Airlines
7.2
Good
10,000 reviews
Delta
8.0
Very good
7,946 reviews

Food

7.3

Entertainment

7.9

Boarding

8.2

Overall

8.0

Comfort

7.9

Crew

8.5

Reviews

1 / 20
10.0
Excellent

Kim,May 2025

PIH - SLC

This trip was fine even with delay I had plenty of time to get connection flight!

Related info for your journey

Find useful and relevant information for your journey from Knoxville to Louisiana. Access travel guides, tips, and recommendations to enhance your travel experience. Get information about local attractions, weather, transportation options, and more.

  • What airport do you fly from for flights from Knoxville to Louisiana?

    Located just 11.3 mi from the city center, Knoxville McGhee Tyson (TYS) is the airport most travelers will use when flying to Louisiana from Knoxville.

  • What are the cheapest airlines to fly from Knoxville to Louisiana one-way?

    $155 is the cheapest one-way deal found within the past few days, from Delta. You may also be able to find cheap deals on United Airlines and American Airlines, with prices starting from $220 and $275, respectively.

  • What are the most popular routes from Knoxville to Louisiana?

    The most popular flight routes from Knoxville to Louisiana are Knoxville McGhee Tyson - New Orleans Louis Armstrong, Knoxville McGhee Tyson - Baton Rouge Ryan and Knoxville McGhee Tyson - Lafayette Regional.

  • Can I find deals for flights from Knoxville to Louisiana that include hotel bookings?

    Yes. In addition to deals on Knoxville to Louisiana flights, Cheapflights offers vacation packages that include both flights and hotel.

  • How can I find direct flights from Knoxville to Louisiana?

    After entering your origin and destination, apply the non-stop filter on the search result page to find direct flights from Knoxville to Louisiana.

  • Can I find deals for business class flights from Knoxville to Louisiana?

    Yes. Cheapflights offers flight deals from Knoxville to Louisiana by cabin class. In addition to browsing deals, you can also filter by cabin class on the search results page after making a search.

  • What is the cheapest month to book a flight from Knoxville to Louisiana?

    Currently, August is the cheapest month in which you can book a flight from Knoxville to Louisiana (average of $256). Flying from Knoxville to Louisiana in April is currently the most expensive (average of $343). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.

See more FAQs

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Alternative routes for Knoxville to Louisiana

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Top 3 airlines flying from Knoxville to Louisiana

Discover the top 3 airlines that operate flights from Knoxville to Louisiana. Compare their services, reliability, and customer satisfaction ratings to choose the airline that best suits your travel preferences and needs. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated June 12, 2025.
AirlineCheapestAverageFlexibilityOn-time
DeltaCheapest$171Average$354FlexibilityNo cancel feeOn-timeN/A
American AirlinesCheapest$228Average$398FlexibilityNo cancel feeOn-time71%
United AirlinesCheapest$253Average$408FlexibilityNo cancel feeOn-time69%

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