HomeSearch by dateVacation packagesHotelsFlight dealsCar rentalTravel tips & news
Los Cabos

$259+ Cheap flights from Des Moines (DSM) to Los Cabos

This is the cheapest one-way flight price found by a Cheapflights user in the last 72 hours by searching for a flight departing on 5/27. Fares are subject to change and may not be available on all flights or dates of travel.
DSM — SJD
Mar 5 — Mar 121
Thu 3/5
Thu 3/12
1 adult, Economy
We work with more than 300 partners to bring you better travel deals

Find cheap flights from Des Moines to Los Cabos with Cheapflights

1. Tell us where you want to go

Enter your travel information like dates, passengers, trip type (one-way or round trip), and preferred cabin class then click “Find deals”

2. Select your favorite providers

We find the providers serving your travel needs. Choose up to four travel providers to compare side-by-side for flights, hotels, or car rentals.

3. Compare prices and book

Review each provider’s pricing and select the best option for you! Book through your favorite provider’s website for a seamless experience.

Cheap flight deals from Des Moines to Los Cabos

Cheapest flights from Des Moines to Los Cabos
Explore the most affordable flight options available from Des Moines to Los Cabos. Find the lowest fares from popular airlines and budget airlines, with prices last updated on February 3, 2026.

This Delta deal was found by Cheapflights users on 1/31. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 3/35:24 am
DSM
-
SJD
2 stops13h 13m
Delta
Fri 3/66:05 am
SJD
-
DSM
2 stops15h 23m
Delta
Deal found 1/31$463
This American Airlines deal was found by Cheapflights users on 2/1. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 2/286:08 pm
DSM
-
SJD
1 stop17h 28m
American Airlines
Wed 3/412:48 pm
SJD
-
DSM
1 stop9h 52m
American Airlines
Deal found 2/1$481
This United Airlines deal was found by Cheapflights users on 2/2. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 3/166:49 pm
DSM
-
SJD
2 stops16h 16m
United Airlines
Fri 3/2711:49 am
SJD
-
DSM
1 stop8h 55m
United Airlines
Deal found 2/2$497
This American Airlines deal was found by Cheapflights users on 2/1. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 4/25:00 am
DSM
-
SJD
1 stop8h 01m
American Airlines
Wed 4/811:32 am
SJD
-
DSM
1 stop10h 17m
American Airlines
Deal found 2/1$509
This American Airlines deal was found by Cheapflights users on 2/2. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 3/197:27 pm
DSM
-
SJD
1 stop16h 09m
American Airlines
Thu 3/261:36 pm
SJD
-
DSM
1 stop17h 25m
American Airlines
Deal found 2/2$511
This United Airlines deal was found by Cheapflights users on 2/1. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 2/279:04 am
DSM
-
SJD
1 stop6h 38m
United Airlines
Tue 3/32:22 pm
SJD
-
DSM
1 stop8h 21m
United Airlines
Deal found 2/1$514
This American Airlines deal was found by Cheapflights users on 2/2. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 2/277:27 pm
DSM
-
SJD
1 stop16h 14m
American Airlines
Tue 3/33:53 pm
SJD
-
DSM
1 stop6h 55m
American Airlines
Deal found 2/2$527
This Delta deal was found by Cheapflights users on 2/2. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 4/26:55 am
DSM
-
SJD
2 stops13h 40m
Delta
Wed 4/88:35 am
SJD
-
DSM
2 stops12h 03m
Delta
Deal found 2/2$547
This Aeromexico deal was found by Cheapflights users on 2/1. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Aeromexico is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 5/87:06 am
DSM
-
SJD
2 stops12h 44m
Aeromexico
Tue 5/126:55 pm
SJD
-
DSM
2 stops20h 58m
Aeromexico
Deal found 2/1$550
This Aeromexico deal was found by Cheapflights users on 2/3. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Aeromexico is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 5/67:00 am
DSM
-
SJD
2 stops17h 25m
Aeromexico
Sun 5/106:40 pm
SJD
-
DSM
2 stops25h 52m
Aeromexico
Deal found 2/3$555
This Delta deal was found by Cheapflights users on 2/1. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 9/167:00 am
DSM
-
SJD
2 stops12h 41m
Delta
Wed 9/2312:15 pm
SJD
-
DSM
1 stop8h 11m
Delta
Deal found 2/1$562

Find flight deals from Des Moines to Los Cabos

Keep the following information in mind while searching for Des Moines to Los Cabos flight deals. Data was last updated February 3, 2026.

Most accurate provider

FlightHub
3 stars

Most trusted provider

FlightHub
3 stars

Round-trip from

$463
(Delta)

One-way from

$259
(American Airlines)

Popular in

December

Cheapest in

October

Average price

$640
Provider with most accurate pricing for Des Moines-San José del Cabo Los Cabos flight deals.
Search Deals
Provider most trusted by Cheapflights users for Des Moines-San José del Cabo Los Cabos flights.
Search Deals
From Des Moines to Los Cabos
Search Deals
One-way flight from Des Moines to Los Cabos
Search Deals
Highest demand for flights based on searches. 10% potential increase in price ($73 potential increase over avg. RT price).
Search Deals
Cheapest flight prices on average. 3% potential price decrease ($24 potential savings vs. average RT price).
Search Deals
Average for round-trip flights in February 2026
Search Deals

Cheapflights Fare Finder

 
Customize your flight search to find flights from Des Moines to Los Cabos that fit within your specific budget. Explore options based on user searches and filter the results based on your desired price range. Find flights that match your budget for a cost-effective journey. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated February 3, 2026.
Use the filters below to find and compare flights from Des Moines to Los Cabos that are best for you.

Fly from

Des Moines

Fly to

Los Cabos

Route

Depart

Return

Price

Des MoinesSan José del Cabo

DSM - SJD

DSMSJD

Des Moines

Tue 3/3

5:24 am-12:40 pm

1 stop8h 16m

San José del Cabo Los Cabos

Fri 3/6

6:05 am-10:28 pm

2 stops15h 23m

$463

Des MoinesSan José del Cabo

DSM - SJD

DSMSJD

Des Moines

Tue 3/17

5:00 am-12:36 pm

1 stop9h 36m

San José del Cabo Los Cabos

Fri 3/27

2:48 pm-11:42 pm

1 stop6h 54m

$464

Des MoinesSan José del Cabo

DSM - SJD

DSMSJD

Des Moines

Tue 4/7

6:55 am-10:25 pm

2 stops17h 30m

San José del Cabo Los Cabos

Tue 4/14

6:55 pm-5:45 pm

2 stops20h 50m

$464

Des MoinesSan José del Cabo

DSM - SJD

DSMSJD

Des Moines

Wed 3/25

5:35 am-11:30 am

1 stop7h 55m

San José del Cabo Los Cabos

Wed 4/1

12:35 pm-10:38 pm

1 stop8h 03m

$464

Des MoinesSan José del Cabo

DSM - SJD

DSMSJD

Des Moines

Mon 3/16

7:44 pm-11:03 am

1 stop17h 19m

San José del Cabo Los Cabos

Fri 3/27

4:34 pm-10:44 am

1 stop16h 10m

$464

Des MoinesSan José del Cabo

DSM - SJD

DSMSJD

Des Moines

Wed 5/27

6:00 am-11:30 am

1 stop7h 30m

$259

Des MoinesSan José del Cabo

DSM - SJD

DSMSJD

Des Moines

Wed 5/27

5:29 am-10:25 pm

2 stops18h 56m

$299

Des MoinesSan José del Cabo

DSM - SJD

DSMSJD

Des Moines

Thu 5/28

7:05 pm-8:10 am

2 stops15h 05m

$299

Des MoinesSan José del Cabo

DSM - SJD

DSMSJD

Des Moines

Tue 2/17

5:00 am-3:28 pm

1 stop11h 28m

$304

Des MoinesSan José del Cabo

DSM - SJD

DSMSJD

Des Moines

Tue 2/17

12:02 pm-9:31 am

2 stops22h 29m

$364

Flights are sorted by cheapest round-trip flights first.

Deals found on 2/1

Best time to book a flight from Des Moines to Los Cabos

Have a flexible travel schedule? Discover the best time to fly to Los Cabos from Des Moines with our price prediction graph.
Estimated round-trip price
Rates are based on past data. Find the cheapest month and day to book your flight based on your travel requirements, then search for cheap deals.

Cheapflights Insights

Everything you need to know about your flight from Des Moines to Los Cabos

What is the cheapest month to book a flight from Des Moines to Los Cabos?

Currently, November is the cheapest month in which you can book a flight from Des Moines to Los Cabos (average of $351). Flying from Des Moines to Los Cabos in December is currently the most expensive (average of $601). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.

Reviews of airlines servicing Los Cabos

Get insights into the airlines that provide service to Los Cabos. Read reviews, discover amenities, and learn about the overall travel experience offered by airlines. Use this information to make informed decisions when choosing an airline for your flight to Los Cabos. Reviews last updated February 3, 2026.
Peruse reviews from past customers who have flown with United Airlines and American Airlines from Des Moines to Los Cabos to help guide your decision. Reviews also offer insight into each airline's entertainment options, comfort, food, crew/service, and boarding process.
United Airlines
7.4
Good
9,236 reviews

Boarding

7.7

Comfort

7.3

Entertainment

7.1

Crew

8.1

Food

6.6

Overall

7.4

Reviews

1 / 20
10.0
Excellent

Dane,Jan 2026

TYS - IAD

It was a short flight, so no time for amenities. Just glad everything was quick and easy from boarding to arriving at my destination with my family
United Airlines
7.4
Good
9,236 reviews
United Airlines
7.4
Good
9,236 reviews

Boarding

7.7

Comfort

7.3

Entertainment

7.1

Crew

8.1

Food

6.6

Overall

7.4

Reviews

1 / 20
10.0
Excellent

Dane,Jan 2026

TYS - IAD

It was a short flight, so no time for amenities. Just glad everything was quick and easy from boarding to arriving at my destination with my family
American Airlines
7.2
Good
11,216 reviews
United Airlines
7.4
Good
9,236 reviews

Boarding

7.7

Comfort

7.3

Entertainment

7.1

Crew

8.1

Food

6.6

Overall

7.4

Reviews

1 / 20
10.0
Excellent

Dane,Jan 2026

TYS - IAD

It was a short flight, so no time for amenities. Just glad everything was quick and easy from boarding to arriving at my destination with my family

Related info for your journey

Find useful and relevant information for your journey from Des Moines to Los Cabos. Access travel guides, tips, and recommendations to enhance your travel experience. Get information about local attractions, weather, transportation options, and more.

  • What airport do you fly from for flights from Des Moines to Los Cabos?

    Located just 3.6 mi from the city center, Des Moines (DSM) is the airport most travelers will use when flying to Los Cabos from Des Moines.

  • How long is the flight from Des Moines to Los Cabos?

    Delta and American Airlines can get you from Des Moines to Los Cabos in just under 8h 16m. Your travel time can differ by up to 1h 20m. Des Moines and Los Cabos are separated by a distance of 1572 mi. This flight may include one or multiple stops.

  • Can I find deals for flights from Des Moines to Los Cabos that include hotel bookings?

    Yes. In addition to deals on Des Moines to Los Cabos flights, Cheapflights offers vacation packages that include both flights and hotel.

  • How can I find direct flights from Des Moines to Los Cabos?

    After entering your origin and destination, apply the non-stop filter on the search result page to find direct flights from Des Moines to Los Cabos.

  • Can I find deals for business class flights from Des Moines to Los Cabos?

    Yes. Cheapflights offers flight deals from Des Moines to Los Cabos by cabin class. In addition to browsing deals, you can also filter by cabin class on the search results page after making a search.

  • What is the cheapest month to book a flight from Des Moines to Los Cabos?

    Currently, November is the cheapest month in which you can book a flight from Des Moines to Los Cabos (average of $351). Flying from Des Moines to Los Cabos in December is currently the most expensive (average of $601). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.

See more FAQs

Browse thousands of different options on Cheapflights for your next trip

Toggle through the tabs below to find thousands of options on Cheapflights for your next trip.

Alternative routes for Des Moines to Los Cabos

See prices for flight routes from nearby airports that may be better suited for you.
Des Moines to San José del Cabo flights
Omaha to San José del Cabo flights
Cedar Rapids to San José del Cabo flights
Moline to San José del Cabo flights
Sioux City to San José del Cabo flights

Top 2 airlines flying from Des Moines to Los Cabos

Discover the top 2 airlines that operate flights from Des Moines to Los Cabos. Compare their services, reliability, and customer satisfaction ratings to choose the airline that best suits your travel preferences and needs. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated February 3, 2026.
AirlineCheapestAverageFlexibilityOn-time
American AirlinesCheapest$389Average$595FlexibilityNo cancel feeOn-time71%
United AirlinesCheapest$423Average$640FlexibilityNo cancel feeOn-time69%

100% Free

Cheapflights is completely free to use, so you can start saving the moment you arrive.

Book with Flexibility

Our users can plan ahead with confidence and find flights with no change fees

Travel Smart

Millions of people come to us for their flight needs every year. We help make travel planning easy by providing useful insights and data-driven graphs that can inform your decisions.