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Grand Cayman

$276+ Cheap flights from Des Moines (DSM) to Grand Cayman

This is the cheapest one-way flight price found by a Cheapflights user in the last 72 hours by searching for a flight departing on 10/15. Fares are subject to change and may not be available on all flights or dates of travel.
DSM — GCM
Jul 5 — Jul 121
Sat 7/5
Sat 7/12
1 adult, Economy
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Cheap flight deals from Des Moines to Grand Cayman

Keep the following information in mind while searching for Des Moines to Grand Cayman flight deals. Data was last updated June 30, 2025.

Round-trip from

$601
(American Airlines)

One-way from

$276
(Mytrip)

Popular in

December

Cheapest in

August

Average price

$667
From Des Moines to Grand Cayman
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One-way flight from Des Moines to Grand Cayman
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Highest demand for flights based on searches. 9% potential increase in price ($77 potential increase over avg. RT price).
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Cheapest flight prices on average. 5% potential price decrease ($35 potential savings vs. average RT price).
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Average for round-trip flights in June 2025
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Find flight deals from Des Moines to Grand Cayman

Cheapest flights from Des Moines to Grand Cayman
Explore the most affordable flight options available from Des Moines to Grand Cayman. Find the lowest fares from popular airlines and budget airlines, with prices last updated on June 30, 2025.

This American Airlines deal was found by Cheapflights users on 6/30. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 10/126:10 pmDSM - GCM
1 stop17h 15mAmerican Airlines
Sat 10/183:05 pmGCM - DSM
1 stop8h 11mAmerican Airlines
Deal found 6/30$601
This United Airlines deal was found by Cheapflights users on 6/29. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 12/276:45 pmDSM - GCM
2 stops20h 45mUnited Airlines
Sat 1/176:00 pmGCM - DSM
2 stops17h 20mUnited Airlines
Deal found 6/29$847

Cheapflights Fare Finder

Customize your flight search to find flights from Des Moines to Grand Cayman that fit within your specific budget. Explore options based on user searches and filter the results based on your desired price range. Find flights that match your budget for a cost-effective journey. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated June 30, 2025.
Use the filters below to find and compare flights from Des Moines to Grand Cayman that are best for you.

Fly from

Des Moines

Fly to

Grand Cayman

Route

Depart

Return

Price

Des MoinesGeorge Town

DSM - GCM

DSMGCM

Des Moines

Sun 10/12

6:10 pm-11:25 am

1 stop17h 15m

George Town Owen Roberts Intl

Sat 10/18

3:05 pm-11:16 pm

1 stop8h 11m

$601

Des MoinesGeorge Town

DSM - GCM

DSMGCM

Des Moines

Sat 12/27

6:45 pm-4:30 pm

2 stops20h 45m

George Town Owen Roberts Intl

Sat 1/17

6:00 pm-10:20 am

2 stops17h 20m

$847

Des MoinesGeorge Town

DSM - GCM

DSMGCM

Des Moines

Wed 10/15

7:30 am-9:20 pm

3 stops37h 50m

$276

Des MoinesGeorge Town

DSM - GCM

DSMGCM

Des Moines

Wed 10/15

5:35 pm-11:42 am

2 stops18h 07m

$283

Des MoinesGeorge Town

DSM - GCM

DSMGCM

Des Moines

Sun 7/27

6:09 pm-11:22 am

2 stops17h 13m

$293

Des MoinesGeorge Town

DSM - GCM

DSMGCM

Des Moines

Sun 7/27

6:50 pm-12:30 pm

2 stops17h 40m

$655

Flights are sorted by cheapest round-trip flights first.

Deals found on 6/30

Best time to book a flight from Des Moines to Grand Cayman

Have a flexible travel schedule? Discover the best time to fly to Grand Cayman from Des Moines with our price prediction graph.
Estimated round-trip price
Rates are based on past data. Find the cheapest month and day to book your flight based on your travel requirements, then search for cheap deals.

Cheapflights Insights

Everything you need to know about your flight from Des Moines to Grand Cayman

What is the cheapest time of day to fly from DSM to LAW?

Find hourly flight availability from Des Moines to Grand Cayman. Discover flight options and departure times throughout the day, allowing you to choose a departure time that suits your schedule. Data last updated June 30, 2025.

When flying from Des Moines to Grand Cayman, the time of day you decide to fly out makes little to no difference towards the overall price you’ll pay on tickets.

Reviews of airlines servicing Grand Cayman

Get insights into the airlines that provide service to Grand Cayman. Read reviews, discover amenities, and learn about the overall travel experience offered by airlines. Use this information to make informed decisions when choosing an airline for your flight to Grand Cayman. Reviews last updated June 30, 2025.
Read reviews from past customers who have flown Delta, United Airlines, and American Airlines from Des Moines to Grand Cayman. You can also see how each airline compares in terms of entertainment options, comfort, food, crew/service, and boarding process.
Delta
8.0
Very good
7,973 reviews

Comfort

7.9

Boarding

8.2

Food

7.3

Crew

8.5

Entertainment

7.9

Overall

8.0

Reviews

1 / 20
10.0
Excellent

Kim,May 2025

PIH - SLC

This trip was fine even with delay I had plenty of time to get connection flight!
Delta
8.0
Very good
7,973 reviews
Delta
8.0
Very good
7,973 reviews

Comfort

7.9

Boarding

8.2

Food

7.3

Crew

8.5

Entertainment

7.9

Overall

8.0

Reviews

1 / 20
10.0
Excellent

Kim,May 2025

PIH - SLC

This trip was fine even with delay I had plenty of time to get connection flight!
United Airlines
7.4
Good
8,852 reviews
Delta
8.0
Very good
7,973 reviews

Comfort

7.9

Boarding

8.2

Food

7.3

Crew

8.5

Entertainment

7.9

Overall

8.0

Reviews

1 / 20
10.0
Excellent

Kim,May 2025

PIH - SLC

This trip was fine even with delay I had plenty of time to get connection flight!
American Airlines
7.2
Good
10,000 reviews
Delta
8.0
Very good
7,973 reviews

Comfort

7.9

Boarding

8.2

Food

7.3

Crew

8.5

Entertainment

7.9

Overall

8.0

Reviews

1 / 20
10.0
Excellent

Kim,May 2025

PIH - SLC

This trip was fine even with delay I had plenty of time to get connection flight!

Related info for your journey

Find useful and relevant information for your journey from Des Moines to Grand Cayman. Access travel guides, tips, and recommendations to enhance your travel experience. Get information about local attractions, weather, transportation options, and more.

  • What airport do you fly from for flights from Des Moines to Grand Cayman?

    If you book a flight to Grand Cayman from Des Moines, you will be flying from Des Moines, which is the city’s only airport. Des Moines (DSM) is located 3.6 mi from the center of Des Moines.

  • What are the cheapest airlines to fly from Des Moines to Grand Cayman one-way?

    The cheapest airline one-way is Delta, with whom users have recently found tickets for as low as $283. However, be on the lookout for offers from American Airlines and United Airlines, as they are both options that can get you from Des Moines to Grand Cayman for a low price.

  • Can I find deals for flights from Des Moines to Grand Cayman that include hotel bookings?

    Yes. In addition to deals on Des Moines to Grand Cayman flights, Cheapflights offers vacation packages that include both flights and hotel.

  • How can I find direct flights from Des Moines to Grand Cayman?

    After entering your origin and destination, apply the non-stop filter on the search result page to find direct flights from Des Moines to Grand Cayman.

  • Can I find deals for business class flights from Des Moines to Grand Cayman?

    Yes. Cheapflights offers flight deals from Des Moines to Grand Cayman by cabin class. In addition to browsing deals, you can also filter by cabin class on the search results page after making a search.

  • What is the cheapest month to book a flight from Des Moines to Grand Cayman?

    Currently, January is the cheapest month in which you can book a flight from Des Moines to Grand Cayman (average of $467). Flying from Des Moines to Grand Cayman in March is currently the most expensive (average of $594). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.

See more FAQs

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Alternative routes for Des Moines to Grand Cayman

See prices for flight routes from nearby airports that may be better suited for you.
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Top 2 airlines flying from Des Moines to Grand Cayman

Discover the top 2 airlines that operate flights from Des Moines to Grand Cayman. Compare their services, reliability, and customer satisfaction ratings to choose the airline that best suits your travel preferences and needs. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated June 30, 2025.
AirlineCheapestAverageFlexibilityOn-time
United AirlinesCheapest$457Average$605FlexibilityNo cancel feeOn-time69%
American AirlinesCheapest$542Average$644FlexibilityNo cancel feeOn-time71%

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