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Cayman Islands

$595+ Cheap flights from Des Moines (DSM) to the Cayman Islands

This is the cheapest round-trip flight price found by a Cheapflights user in the last 72 hours by searching for a flight departing on 8/23. Fares are subject to change and may not be available on all flights or dates of travel.
DSM — GCM
May 28 — Jun 41
Wed 5/28
Wed 6/4
1 adult, Economy
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Cheap flight deals from Des Moines to Cayman Islands

Keep the following information in mind while searching for Des Moines to Cayman Islands flight deals. Data was last updated May 23, 2025.

Most accurate provider

AranGrant
3 stars

Most trusted provider

AranGrant
3 stars

Round-trip from

$595
(American Airlines)

Popular in

December

Cheapest in

August

Average price

$679
Provider with most accurate pricing for Des Moines-George Town Owen Roberts Intl flight deals.
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Provider most trusted by Cheapflights users for Des Moines-George Town Owen Roberts Intl flights.
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From Des Moines to Cayman Islands
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Highest demand for flights based on searches. 7% potential increase in price ($55 potential increase over avg. RT price).
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Cheapest flight prices on average. 3% potential price decrease ($25 potential savings vs. average RT price).
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Average for round-trip flights in May 2025
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Find flight deals from Des Moines to Cayman Islands

Cheapest flights from Des Moines to Cayman Islands
Explore the most affordable flight options available from Des Moines to Cayman Islands. Find the lowest fares from popular airlines and budget airlines, with prices last updated on May 23, 2025.

This American Airlines deal was found by Cheapflights users on 5/22. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 8/233:49 pmDSM - GCM
2 stops21h 21mAmerican Airlines
Sat 8/303:15 pmGCM - DSM
2 stops8h 30mAmerican Airlines
Deal found 5/22$595
This Delta deal was found by Cheapflights users on 5/22. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 8/235:44 amDSM - GCM
1 stop5h 53mDelta
Sat 8/3012:52 pmGCM - DSM
1 stop9h 51mDelta
Deal found 5/22$616
This Mytrip deal was found by Cheapflights users on 5/22. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Mytrip is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 7/610:31 pmDSM - GCM
3 stops22h 49mMultiple Airlines
Sun 7/1312:40 pmGCM - DSM
2 stops25h 09mMultiple Airlines
Deal found 5/22$868

Cheapflights Fare Finder

Customize your flight search to find flights from Des Moines to Cayman Islands that fit within your specific budget. Explore options based on user searches and filter the results based on your desired price range. Find flights that match your budget for a cost-effective journey. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated May 23, 2025.
Use the filters below to find and compare flights from Des Moines to the Cayman Islands that are best for you.

Fly from

Des Moines

Fly to

Cayman Islands

Route

Depart

Return

Price

Des MoinesGeorge Town

DSM - GCM

DSMGCM

Des Moines

Sat 8/23

3:49 pm-1:10 pm

2 stops21h 21m

George Town Owen Roberts Intl

Sat 8/30

3:15 pm-11:45 pm

2 stops8h 30m

$595

Des MoinesGeorge Town

DSM - GCM

DSMGCM

Des Moines

Sat 8/23

5:44 am-11:37 am

1 stop5h 53m

George Town Owen Roberts Intl

Sat 8/30

12:52 pm-10:43 pm

1 stop9h 51m

$616

Des MoinesGeorge Town

DSM - GCM

DSMGCM

Des Moines

Sun 7/6

10:31 pm-9:20 pm

3 stops22h 49m

George Town Owen Roberts Intl

Sun 7/13

12:40 pm-1:49 pm

2 stops25h 09m

$868

Flights are sorted by cheapest round-trip flights first.

Deals found on 5/22

Best time to book a flight from Des Moines to Cayman Islands

Have a flexible travel schedule? Discover the best time to fly to Cayman Islands from Des Moines with our price prediction graph.
Estimated round-trip price
Rates are based on past data. Find the cheapest month and day to book your flight based on your travel requirements, then search for cheap deals.

Cheapflights Insights

Everything you need to know about your flight from Des Moines to the Cayman Islands

What is the cheapest time of day to fly from DSM to KY?

Find hourly flight availability from Des Moines to Cayman Islands. Discover flight options and departure times throughout the day, allowing you to choose a departure time that suits your schedule. Data last updated May 23, 2025.

Regardless of the time of day you decide to fly, the ticket price will remain around the same. Book flights from Des Moines to Cayman Islands as you normally would.

Reviews of airlines servicing Cayman Islands

Get insights into the airlines that provide service to Cayman Islands. Read reviews, discover amenities, and learn about the overall travel experience offered by airlines. Use this information to make informed decisions when choosing an airline for your flight to Cayman Islands. Reviews last updated May 23, 2025.
Delta
8.0
Very good
7,950 reviews

Comfort

7.9

Overall

8.0

Crew

8.5

Boarding

8.2

Food

7.3

Entertainment

7.9

Reviews

1 / 20
10.0
Excellent

Kim,May 2025

PIH - SLC

This trip was fine even with delay I had plenty of time to get connection flight!
Delta
8.0
Very good
7,950 reviews
Delta
8.0
Very good
7,950 reviews

Comfort

7.9

Overall

8.0

Crew

8.5

Boarding

8.2

Food

7.3

Entertainment

7.9

Reviews

1 / 20
10.0
Excellent

Kim,May 2025

PIH - SLC

This trip was fine even with delay I had plenty of time to get connection flight!
American Airlines
7.2
Good
10,000 reviews
Delta
8.0
Very good
7,950 reviews

Comfort

7.9

Overall

8.0

Crew

8.5

Boarding

8.2

Food

7.3

Entertainment

7.9

Reviews

1 / 20
10.0
Excellent

Kim,May 2025

PIH - SLC

This trip was fine even with delay I had plenty of time to get connection flight!

Related info for your journey

Find useful and relevant information for your journey from Des Moines to Cayman Islands. Access travel guides, tips, and recommendations to enhance your travel experience. Get information about local attractions, weather, transportation options, and more.

  • What airport do you fly from for flights from Des Moines to Cayman Islands?

    Most people fly from Des Moines (DSM) if they book a flight from Des Moines to Cayman Islands. Des Moines is conveniently located just 3.6 mi from Des Moines’s city center.

  • Can I find deals for flights from Des Moines to Cayman Islands that include hotel bookings?

    Yes. In addition to deals on Des Moines to Cayman Islands flights, Cheapflights offers vacation packages that include both flights and hotel.

  • How can I find direct flights from Des Moines to Cayman Islands?

    After entering your origin and destination, apply the non-stop filter on the search result page to find direct flights from Des Moines to Cayman Islands.

  • Can I find deals for business class flights from Des Moines to Cayman Islands?

    Yes. Cheapflights offers flight deals from Des Moines to Cayman Islands by cabin class. In addition to browsing deals, you can also filter by cabin class on the search results page after making a search.

  • What is the cheapest month to book a flight from Des Moines to Cayman Islands?

    Currently, January is the cheapest month in which you can book a flight from Des Moines to Cayman Islands (average of $467). Flying from Des Moines to Cayman Islands in March is currently the most expensive (average of $594). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.

See more FAQs

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Top 2 airlines flying from Des Moines to Cayman Islands

Discover the top 2 airlines that operate flights from Des Moines to Cayman Islands. Compare their services, reliability, and customer satisfaction ratings to choose the airline that best suits your travel preferences and needs. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated May 23, 2025.
AirlineCheapestAverageFlexibilityOn-time
United AirlinesCheapest$457Average$609FlexibilityNo cancel feeOn-time69%
American AirlinesCheapest$542Average$627FlexibilityNo cancel feeOn-time71%

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