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$322+ Cheap flights from Knoxville to Lafayette (TYS - LFT)

This is the cheapest one-way flight price found by a Cheapflights user in the last 72 hours by searching for a flight departing on 8/9. Fares are subject to change and may not be available on all flights or dates of travel.
TYS — LFT
Aug 3 — Aug 101
Sun 8/3
Sun 8/10
1 adult, Economy
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Cheap flight deals from Knoxville to Lafayette

Discover tips and strategies to find the most affordable flight options for your journey from Knoxville (TYS) to Lafayette (LFT). Learn about various techniques such as flexible date searches, comparing prices across and setting up price alerts. Use these methods to find the cheapest flights available for your travel needs. Data last updated July 29, 2025.

Round-trip from

$428
(American Airlines)

One-way from

$322
(American Airlines)
From Knoxville McGhee Tyson to Lafayette Regional
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One-way flight from Knoxville McGhee Tyson to Lafayette Regional
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Find flight deals from Knoxville to Lafayette

Cheapest flights from Knoxville to Lafayette
Explore the most affordable flight options available from Knoxville to Lafayette. Find the lowest fares from popular airlines and budget airlines, with prices last updated on July 29, 2025.

This American Airlines deal was found by Cheapflights users on 7/26. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 10/106:00 amTYS - LFT
1 stop4h 35mAmerican Airlines
Sun 10/1910:05 amLFT - TYS
1 stop6h 27mAmerican Airlines
Deal found 7/26$428

Cheapflights Fare Finder

 
Customize your flight search to find flights from Knoxville to Lafayette that fit within your specific budget. Explore options based on user searches and filter the results based on your desired price range. Find flights that match your budget for a cost-effective journey. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated July 29, 2025.
Use the filters below to find and compare flights from Knoxville to Lafayette that are best for you.

Fly from

Knoxville

Fly to

Lafayette

Route

Depart

Return

Price

KnoxvilleLafayette

TYS - LFT

TYSLFT

Knoxville McGhee Tyson

Fri 10/10

6:00 am-9:35 am

1 stop4h 35m

Lafayette Regional

Sun 10/19

10:05 am-5:32 pm

1 stop6h 27m

$428

KnoxvilleLafayette

TYS - LFT

TYSLFT

Knoxville McGhee Tyson

Sat 8/9

6:04 pm-9:52 pm

1 stop4h 48m

$322

KnoxvilleLafayette

TYS - LFT

TYSLFT

Knoxville McGhee Tyson

Sat 8/9

12:03 pm-4:59 pm

1 stop5h 56m

$329

KnoxvilleLafayette

TYS - LFT

TYSLFT

Knoxville McGhee Tyson

Sat 8/9

7:00 am-1:21 pm

3 stops31h 21m

$357

Flights are sorted by cheapest round-trip flights first.

Deals found on 7/26

Best time to book a flight from Knoxville to Lafayette

Have a flexible travel schedule? Discover the best time to fly to Lafayette from Knoxville with our price prediction graph.
Estimated round-trip price
Rates are based on past data. Find the cheapest month and day to book your flight based on your travel requirements, then search for cheap deals.

Cheapflights Insights

Everything you need to know about your flight from Knoxville to Lafayette

What is the cheapest month to book a flight from Knoxville to Lafayette?

Currently, November is the cheapest month in which you can book a flight from Knoxville to Lafayette (average of $323). Flying from Knoxville to Lafayette in March is currently the most expensive (average of $436). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.

What is the cheapest time of day to fly from TYS to LFT?

Find hourly flight availability from Knoxville to Lafayette. Discover flight options and departure times throughout the day, allowing you to choose a departure time that suits your schedule. Data last updated July 29, 2025.

When flying from Knoxville to Lafayette, the time of day you fly usually plays a role in the price. Save by searching for a flight in the afternoon, which can drop the price by up to 27% versus a flight in the morning.

Reviews of airlines servicing Lafayette

Get insights into the airlines that provide service to Lafayette. Read reviews, discover amenities, and learn about the overall travel experience offered by airlines. Use this information to make informed decisions when choosing an airline for your flight to Lafayette. Reviews last updated July 29, 2025.
See what other customers who have flown with Delta, United Airlines, and American Airlines from Knoxville to Lafayette have to say. You can also see how each airline compares in terms of entertainment options, comfort, food, crew/service, and boarding process.
Delta
8.0
Very good
7,977 reviews

Crew

8.5

Boarding

8.2

Entertainment

7.9

Comfort

7.9

Food

7.3

Overall

8.0

Reviews

1 / 20
10.0
Excellent

Kim,May 2025

PIH - SLC

This trip was fine even with delay I had plenty of time to get connection flight!
Delta
8.0
Very good
7,977 reviews
Delta
8.0
Very good
7,977 reviews

Crew

8.5

Boarding

8.2

Entertainment

7.9

Comfort

7.9

Food

7.3

Overall

8.0

Reviews

1 / 20
10.0
Excellent

Kim,May 2025

PIH - SLC

This trip was fine even with delay I had plenty of time to get connection flight!
United Airlines
7.4
Good
8,899 reviews
Delta
8.0
Very good
7,977 reviews

Crew

8.5

Boarding

8.2

Entertainment

7.9

Comfort

7.9

Food

7.3

Overall

8.0

Reviews

1 / 20
10.0
Excellent

Kim,May 2025

PIH - SLC

This trip was fine even with delay I had plenty of time to get connection flight!
American Airlines
7.2
Good
10,000 reviews
Delta
8.0
Very good
7,977 reviews

Crew

8.5

Boarding

8.2

Entertainment

7.9

Comfort

7.9

Food

7.3

Overall

8.0

Reviews

1 / 20
10.0
Excellent

Kim,May 2025

PIH - SLC

This trip was fine even with delay I had plenty of time to get connection flight!

Related info for your journey

Find useful and relevant information for your journey from Knoxville to Lafayette. Access travel guides, tips, and recommendations to enhance your travel experience. Get information about local attractions, weather, transportation options, and more.

  • What is the cheapest airline to fly from Knoxville to Lafayette round-trip?

    Cheapflights users have booked flights from Knoxville to Lafayette round-trip from $428.

  • What are the cheapest airlines to fly from Knoxville to Lafayette one-way?

    One-way options have recently been found by users for as low as $322 on American Airlines. Other airlines that offer cheap prices include Delta from $329 and United Airlines from $357 one-way.

  • Can I find deals for flights from Knoxville to Lafayette that include hotel bookings?

    Yes. In addition to deals on Knoxville to Lafayette flights, Cheapflights offers vacation packages that include both flights and hotel.

  • How can I find direct flights from Knoxville to Lafayette?

    After entering your origin and destination, apply the non-stop filter on the search result page to find direct flights from Knoxville to Lafayette.

  • Can I find deals for business class flights from Knoxville to Lafayette?

    Yes. Cheapflights offers flight deals from Knoxville to Lafayette by cabin class. In addition to browsing deals, you can also filter by cabin class on the search results page after making a search.

  • What is the cheapest month to book a flight from Knoxville to Lafayette?

    Currently, November is the cheapest month in which you can book a flight from Knoxville to Lafayette (average of $323). Flying from Knoxville to Lafayette in March is currently the most expensive (average of $436). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.

See more FAQs

Traveling to a place near Lafayette?

Book flights to Lafayette if you plan to visit one of these locations
Opelousas

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Top airline flying from Knoxville to Lafayette

Discover the top airline that operate flights from Knoxville to Lafayette. Compare their services, reliability, and customer satisfaction ratings to choose the airline that best suits your travel preferences and needs. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated July 29, 2025.
AirlineCheapestAverageFlexibilityOn-time
American AirlinesCheapest$208Average$488FlexibilityNo cancel feeOn-time71%

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