$268+ Cheap flights from Detroit Metropolitan Wayne County Airport to La Crosse (DTW - LSE)
This is the cheapest round-trip flight price found by a Cheapflights user in the last 72 hours by searching for a flight departing on 3/24. Fares are subject to change and may not be available on all flights or dates of travel.
DTW — LSE
Apr 9 — Apr 161
Round-trip
1 adult, Economy
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Find cheap flights from Detroit to La Crosse with Cheapflights
1. Tell us where you want to go
Enter your travel information like dates, passengers, trip type (one-way or round trip), and preferred cabin class then click “Find deals”2. Select your favorite providers
We find the providers serving your travel needs. Choose up to four travel providers to compare side-by-side for flights, hotels, or car rentals.3. Compare prices and book
Review each provider’s pricing and select the best option for you! Book through your favorite provider’s website for a seamless experience.Cheap flight deals from Detroit to La Crosse
Cheapest
Best
Last-minute
One-way
Cheapest flights from Detroit to La CrosseExplore the most affordable flight options available from Detroit to La Crosse. Find the lowest fares from popular airlines and budget airlines, with prices last updated on March 10, 2026.
Explore the most affordable flight options available from Detroit to La Crosse. Find the lowest fares from popular airlines and budget airlines, with prices last updated on March 10, 2026.
This American Airlines deal was found by Cheapflights users on 3/8. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 3/245:45 am
DTW
- LSE
1 stop4h 33m
American Airlines
Sat 3/285:09 am
LSE
- DTW
1 stop3h 47m
American Airlines
Deal found 3/8![American Airlines logo]()
$268
This American Airlines deal was found by Cheapflights users on 3/10. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 3/255:45 am
DTW
- LSE
1 stop6h 16m
American Airlines
Sun 3/295:09 am
LSE
- DTW
1 stop6h 45m
American Airlines
Deal found 3/10![American Airlines logo]()
$288
This American Airlines deal was found by Cheapflights users on 3/6. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 6/28:55 pm
DTW
- LSE
1 stop4h 11m
American Airlines
Thu 6/411:46 am
LSE
- DTW
1 stop4h 13m
American Airlines
Deal found 3/6![American Airlines logo]()
$482
This American Airlines deal was found by Cheapflights users on 3/7. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 8/65:30 am
DTW
- LSE
1 stop18h 48m
American Airlines
Sun 8/96:37 pm
LSE
- DTW
1 stop3h 47m
American Airlines
Deal found 3/7![American Airlines logo]()
$550
Best flights from Detroit to La CrosseDiscover carefully curated flight deals from Detroit to La Crosse that have cost, travel time, and layovers in mind to ensure you get the best travel experience. Data last updated March 10, 2026.
Discover carefully curated flight deals from Detroit to La Crosse that have cost, travel time, and layovers in mind to ensure you get the best travel experience. Data last updated March 10, 2026.
This American Airlines deal was found by Cheapflights users on 3/8. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 3/245:45 am
DTW
- LSE
1 stop4h 33m
American Airlines
Sat 3/285:09 am
LSE
- DTW
1 stop3h 47m
American Airlines
Deal found 3/8![American Airlines logo]()
$268
This American Airlines deal was found by Cheapflights users on 3/10. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 3/255:45 am
DTW
- LSE
1 stop6h 16m
American Airlines
Sun 3/295:09 am
LSE
- DTW
1 stop6h 45m
American Airlines
Deal found 3/10![American Airlines logo]()
$288
This American Airlines deal was found by Cheapflights users on 3/6. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 6/28:55 pm
DTW
- LSE
1 stop4h 11m
American Airlines
Thu 6/411:46 am
LSE
- DTW
1 stop4h 13m
American Airlines
Deal found 3/6![American Airlines logo]()
$482
This American Airlines deal was found by Cheapflights users on 3/7. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 8/65:30 am
DTW
- LSE
1 stop18h 48m
American Airlines
Sun 8/96:37 pm
LSE
- DTW
1 stop3h 47m
American Airlines
Deal found 3/7![American Airlines logo]()
$550
Last-minute flights from Detroit to La CrosseDiscover last-minute flight deals from Detroit to La Crosse. Data last updated March 10, 2026 and is based on user searches.
Discover last-minute flight deals from Detroit to La Crosse. Data last updated March 10, 2026 and is based on user searches.
This American Airlines deal was found by Cheapflights users on 3/8. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 3/245:45 am
DTW
- LSE
1 stop4h 33m
American Airlines
Sat 3/285:09 am
LSE
- DTW
1 stop3h 47m
American Airlines
Deal found 3/8![American Airlines logo]()
$268
This American Airlines deal was found by Cheapflights users on 3/10. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 3/255:45 am
DTW
- LSE
1 stop6h 16m
American Airlines
Sun 3/295:09 am
LSE
- DTW
1 stop6h 45m
American Airlines
Deal found 3/10![American Airlines logo]()
$288
One-way flights from Detroit to La CrosseSearch for one-way flight options from Detroit to La Crosse. Find affordable one-way fares based on user searches. Data last updated March 10, 2026.
Search for one-way flight options from Detroit to La Crosse. Find affordable one-way fares based on user searches. Data last updated March 10, 2026.
This American Airlines deal was found by Cheapflights users on 3/6. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 3/175:45 am
DTW
- LSE
1 stop4h 33m
American Airlines
Deal found 3/6![American Airlines logo]()
$286
Find flight deals from Detroit to La Crosse
Discover tips and strategies to find the most affordable flight options for your journey from Detroit (DTW) to La Crosse (LSE). Learn about various techniques such as flexible date searches, comparing prices across and setting up price alerts. Use these methods to find the cheapest flights available for your travel needs. Data last updated March 10, 2026.
Most accurate provider | FlightHub 3 stars |
|---|---|
Most trusted provider | FlightHub 3 stars |
Round-trip from | $268 (American Airlines) |
Cheapflights Fare Finder
Customize your flight search to find flights from Detroit to La Crosse that fit within your specific budget. Explore options based on user searches and filter the results based on your desired price range. Find flights that match your budget for a cost-effective journey. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated March 10, 2026.
Use the filters below to find and compare flights from Detroit Metropolitan Wayne County Airport to La Crosse that are best for you.
Fly from
Fly to
Route
Depart
Return
Cheapest round-trip
Quickest round-trip
DetroitLa Crosse
DTW - LSE
DTWLSE
Detroit Metropolitan Wayne County
Tue 3/24
5:45 am-9:18 am
1 stop4h 33m
La Crosse
Sat 3/28
5:09 am-9:56 am
1 stop3h 47m
$268
DetroitLa Crosse
DTW - LSE
DTWLSE
Detroit Metropolitan Wayne County
Wed 3/25
5:45 am-11:01 am
1 stop6h 16m
La Crosse
Sun 3/29
5:09 am-12:54 pm
1 stop6h 45m
$288
DetroitLa Crosse
DTW - LSE
DTWLSE
Detroit Metropolitan Wayne County
Tue 6/2
8:55 pm-12:06 am
1 stop4h 11m
La Crosse
Thu 6/4
11:46 am-4:59 pm
1 stop4h 13m
$482
DetroitLa Crosse
DTW - LSE
DTWLSE
Detroit Metropolitan Wayne County
Thu 8/6
5:30 am-11:18 pm
1 stop18h 48m
La Crosse
Sun 8/9
6:37 pm-11:24 pm
1 stop3h 47m
$550
Cheapest one-way
Quickest one-way
DetroitLa Crosse
DTW - LSE
DTWLSE
Detroit Metropolitan Wayne County
Tue 3/17
5:45 am-9:18 am
1 stop4h 33m
$286
Sorted by cheapest first
Compare providers for flights from Detroit to La Crosse
Provider information is updated monthly. Please note that these providers often have deals for this flight, but the availability may vary on a day-by-day basis on Cheapflights.
Use the table below to compare price accuracy, trust ratings, and cancellation policies for each provider offering flight deals from Detroit to La Crosse in March.
| Provider | Price Accuracy | Trust Score* |
|---|---|---|
| Price Accuracy1 star | Trust Score*3 stars | |
| Price Accuracy3 stars | Trust Score*3 stars |
- Most accurate provider: When it comes to deals on Detroit Metropolitan Wayne County Airport-La Crosse flights, users find the pricing of FlightHub to be most consistent on Cheapflights vs. FlightHub Users can find the same prices on Detroit Metropolitan Wayne County Airport-La Crosse flight deals on Cheapflights vs. FlightHub >95% of the time. Price accuracy is based on data collected from Detroit Metropolitan Wayne County Airport-La Crosse flight searches over the past month and is updated monthly.
- Most trusted provider: When it comes to deals on Detroit Metropolitan Wayne County Airport-La Crosse flights, Cheapflights users trust FlightHub the most. FlightHub has received a user feedback score of 3 out of 3 stars (3 being the best), meaning they have been trusted the most by Cheapflights users looking for Detroit Metropolitan Wayne County Airport-La Crosse flight deals. Provider user feedback score is based on Cheapflights searches over the past month and is updated monthly.
Best time to book a flight from Detroit to La Crosse
Have a flexible travel schedule? Discover the best time to fly to La Crosse from Detroit with our price prediction graph.
DTW-LSE
Estimated round-trip price
Rates are based on past data. Find the cheapest month and day to book your flight based on your travel requirements, then search for cheap deals.
Reviews of airlines servicing La Crosse
Get insights into the airlines that provide service to La Crosse. Read reviews, discover amenities, and learn about the overall travel experience offered by airlines. Use this information to make informed decisions when choosing an airline for your flight to La Crosse. Reviews last updated March 10, 2026.
Read reviews from past customers who have flown American Airlines from Detroit Metropolitan Wayne County Airport to La Crosse. Users can see the overall rating for each airline as well as how each is rated in terms of entertainment options, comfort, food, crew/service, and boarding process.
Overall
7.1
Entertainment
6.9
Crew
7.9
Food
6.4
Boarding
7.5
Comfort
7.2
Reviews
1 / 20
2.0
MediocreAnonymous,Mar 2026
MIA - SFO
Overall
7.1
Entertainment
6.9
Crew
7.9
Food
6.4
Boarding
7.5
Comfort
7.2
Reviews
1 / 20
2.0
MediocreAnonymous,Mar 2026
MIA - SFO
Related info for your journey
Find useful and relevant information for your journey from Detroit to La Crosse. Access travel guides, tips, and recommendations to enhance your travel experience. Get information about local attractions, weather, transportation options, and more.
Traveling to a place near La Crosse?
Book flights to La Crosse if you plan to visit one of these locationsDecorah
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Top airline flying from Detroit to La Crosse
Discover the top airline that operate flights from Detroit to La Crosse. Compare their services, reliability, and customer satisfaction ratings to choose the airline that best suits your travel preferences and needs. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated March 10, 2026.
| Airline | Cheapest | Average | Flexibility | On-time |
|---|---|---|---|---|
| Cheapest$414 | Average$468 | FlexibilityNo cancel fee | On-time71% |