$352+ Cheap flights from Detroit Metropolitan Wayne County Airport to La Crosse (DTW - LSE)
This is the cheapest one-way flight price found by a Cheapflights user in the last 72 hours by searching for a flight departing on 10/11. Fares are subject to change and may not be available on all flights or dates of travel.
DTW — LSE
Oct 11 — Oct 181
1 adult, Economy
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Find cheap flights from Detroit to La Crosse with Cheapflights
1. Tell us where you want to go
Enter your travel information like dates, passengers, trip type (one-way or round trip), and preferred cabin class then click “Find deals”2. Select your favorite providers
We find the providers serving your travel needs. Choose up to four travel providers to compare side-by-side for flights, hotels, or car rentals.3. Compare prices and book
Review each provider’s pricing and select the best option for you! Book through your favorite provider’s website for a seamless experience.Cheap flight deals from Detroit to La Crosse
Discover tips and strategies to find the most affordable flight options for your journey from Detroit (DTW) to La Crosse (LSE). Learn about various techniques such as flexible date searches, comparing prices across and setting up price alerts. Use these methods to find the cheapest flights available for your travel needs. Data last updated September 11, 2025.
Round-trip from | $414 (American Airlines) |
|---|---|
One-way from | $352 (American Airlines) |
Find flight deals from Detroit to La Crosse
Cheapest flights from Detroit to La CrosseExplore the most affordable flight options available from Detroit to La Crosse. Find the lowest fares from popular airlines and budget airlines, with prices last updated on September 11, 2025.
Explore the most affordable flight options available from Detroit to La Crosse. Find the lowest fares from popular airlines and budget airlines, with prices last updated on September 11, 2025.
This American Airlines deal was found by Cheapflights users on 9/10. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 11/87:03 pmDTW - LSE
1 stop5h 46mAmerican Airlines
Tue 11/114:45 pmLSE - DTW
1 stop5h 36mAmerican Airlines
Deal found 9/10![American Airlines logo]()
$414
This American Airlines deal was found by Cheapflights users on 9/9. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 9/167:18 pmDTW - LSE
1 stop3h 50mAmerican Airlines
Sat 9/206:00 amLSE - DTW
1 stop4h 54mAmerican Airlines
Deal found 9/9![American Airlines logo]()
$434
This American Airlines deal was found by Cheapflights users on 9/10. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 9/255:43 amDTW - LSE
1 stop4h 56mAmerican Airlines
Mon 9/296:39 pmLSE - DTW
1 stop3h 42mAmerican Airlines
Deal found 9/10![American Airlines logo]()
$520
This American Airlines deal was found by Cheapflights users on 9/10. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 10/311:30 amDTW - LSE
2 stops7h 21mAmerican Airlines
Sun 10/56:00 amLSE - DTW
2 stops8h 18mAmerican Airlines
Deal found 9/10![American Airlines logo]()
$626
Cheapflights Fare Finder
Customize your flight search to find flights from Detroit to La Crosse that fit within your specific budget. Explore options based on user searches and filter the results based on your desired price range. Find flights that match your budget for a cost-effective journey. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated September 11, 2025.
Use the filters below to find and compare flights from Detroit Metropolitan Wayne County Airport to La Crosse that are best for you.
Fly from
Detroit
Fly to
La Crosse
Route
Depart
Return
Price
DetroitLa Crosse
DTW - LSE
DTWLSE
Detroit Metropolitan Wayne County
Sat 11/8
7:03 pm-11:49 pm
1 stop5h 46m
La Crosse
Tue 11/11
4:45 pm-11:21 pm
1 stop5h 36m
$414
DetroitLa Crosse
DTW - LSE
DTWLSE
Detroit Metropolitan Wayne County
Fri 10/3
7:17 pm-10:08 pm
1 stop3h 51m
La Crosse
Sun 10/5
6:00 am-12:34 pm
1 stop5h 34m
$520
DetroitLa Crosse
DTW - LSE
DTWLSE
Detroit Metropolitan Wayne County
Thu 9/25
5:43 am-9:39 am
1 stop4h 56m
La Crosse
Mon 9/29
6:39 pm-11:21 pm
1 stop3h 42m
$520
DetroitLa Crosse
DTW - LSE
DTWLSE
Detroit Metropolitan Wayne County
Sat 10/11
7:00 am-10:24 am
1 stop4h 24m
$352
Best time to book a flight from Detroit to La Crosse
Have a flexible travel schedule? Discover the best time to fly to La Crosse from Detroit with our price prediction graph.
Estimated round-trip price
Rates are based on past data. Find the cheapest month and day to book your flight based on your travel requirements, then search for cheap deals.
Reviews of airlines servicing La Crosse
Get insights into the airlines that provide service to La Crosse. Read reviews, discover amenities, and learn about the overall travel experience offered by airlines. Use this information to make informed decisions when choosing an airline for your flight to La Crosse. Reviews last updated September 11, 2025.
Read reviews from past customers who have flown American Airlines from Detroit Metropolitan Wayne County Airport to La Crosse. Users can see the overall rating for each airline as well as how each is rated in terms of entertainment options, comfort, food, crew/service, and boarding process.
Entertainment
6.9
Food
6.4
Overall
7.2
Comfort
7.2
Crew
8.0
Boarding
7.5
Reviews
1 / 20
2.0
MediocreJeremy,Sep 2025
SAN - PHL
Entertainment
6.9
Food
6.4
Overall
7.2
Comfort
7.2
Crew
8.0
Boarding
7.5
Reviews
1 / 20
2.0
MediocreJeremy,Sep 2025
SAN - PHL
Related info for your journey
Find useful and relevant information for your journey from Detroit to La Crosse. Access travel guides, tips, and recommendations to enhance your travel experience. Get information about local attractions, weather, transportation options, and more.
Traveling to a place near La Crosse?
Book flights to La Crosse if you plan to visit one of these locationsWinona
Decorah
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Alternative routes for Detroit to La Crosse
See prices for flight routes from nearby airports that may be better suited for you.
Top airline flying from Detroit to La Crosse
Discover the top airline that operate flights from Detroit to La Crosse. Compare their services, reliability, and customer satisfaction ratings to choose the airline that best suits your travel preferences and needs. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated September 11, 2025.
| Airline | Cheapest | Average | Flexibility | On-time |
|---|---|---|---|---|
| Cheapest$414 | Average$468 | FlexibilityNo cancel fee | On-time71% |