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La Crosse

$382+ Cheap flights from Detroit Metropolitan Wayne County Airport to La Crosse (DTW - LSE)

This is the cheapest one-way flight price found by a Cheapflights user in the last 72 hours by searching for a flight departing on 3/3. Fares are subject to change and may not be available on all flights or dates of travel.
DTW — LSE
Feb 25 — Mar 41
Wed 2/25
Wed 3/4
1 adult, Economy
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Cheap flight deals from Detroit to La Crosse

Cheapest flights from Detroit to La Crosse
Explore the most affordable flight options available from Detroit to La Crosse. Find the lowest fares from popular airlines and budget airlines, with prices last updated on January 26, 2026.

This American Airlines deal was found by Cheapflights users on 1/24. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 2/121:02 pm
DTW
-
LSE
1 stop5h 57m
American Airlines
Sat 2/145:20 am
LSE
-
DTW
1 stop3h 36m
American Airlines
Deal found 1/24$537
This American Airlines deal was found by Cheapflights users on 1/24. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 6/212:52 pm
DTW
-
LSE
1 stop5h 03m
American Airlines
Thu 6/46:00 am
LSE
-
DTW
1 stop5h 21m
American Airlines
Deal found 1/24$811
This American Airlines deal was found by Cheapflights users on 1/23. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 2/231:02 pm
DTW
-
LSE
1 stop5h 57m
American Airlines
Thu 2/265:20 am
LSE
-
DTW
1 stop6h 12m
American Airlines
Deal found 1/23$858

Find flight deals from Detroit to La Crosse

Discover tips and strategies to find the most affordable flight options for your journey from Detroit (DTW) to La Crosse (LSE). Learn about various techniques such as flexible date searches, comparing prices across and setting up price alerts. Use these methods to find the cheapest flights available for your travel needs. Data last updated January 26, 2026.

Most accurate provider

FlightHub
3 stars

Most trusted provider

Expedia
3 stars

Round-trip from

$537
(American Airlines)

One-way from

$382
(American Airlines)
Provider with most accurate pricing for Detroit Metropolitan Wayne County-La Crosse flight deals.
Search Deals
Provider most trusted by Cheapflights users for Detroit Metropolitan Wayne County-La Crosse flights.
Search Deals
From Detroit Metropolitan Wayne County to La Crosse
Search Deals
One-way flight from Detroit Metropolitan Wayne County to La Crosse
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Cheapflights Fare Finder

 
Customize your flight search to find flights from Detroit to La Crosse that fit within your specific budget. Explore options based on user searches and filter the results based on your desired price range. Find flights that match your budget for a cost-effective journey. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated January 26, 2026.
Use the filters below to find and compare flights from Detroit Metropolitan Wayne County Airport to La Crosse that are best for you.

Fly from

Detroit

Fly to

La Crosse

Route

Depart

Return

Price

DetroitLa Crosse

DTW - LSE

DTWLSE

Detroit Metropolitan Wayne County

Thu 2/12

1:02 pm-5:59 pm

1 stop5h 57m

La Crosse

Sat 2/14

5:20 am-9:56 am

1 stop3h 36m

$537

DetroitLa Crosse

DTW - LSE

DTWLSE

Detroit Metropolitan Wayne County

Mon 2/23

1:02 pm-5:59 pm

1 stop5h 57m

La Crosse

Thu 2/26

5:20 am-12:32 pm

1 stop6h 12m

$858

DetroitLa Crosse

DTW - LSE

DTWLSE

Detroit Metropolitan Wayne County

Tue 3/3

2:11 pm-5:59 pm

1 stop4h 48m

$382

DetroitLa Crosse

DTW - LSE

DTWLSE

Detroit Metropolitan Wayne County

Tue 3/10

2:06 pm-5:59 pm

1 stop4h 53m

$382

DetroitLa Crosse

DTW - LSE

DTWLSE

Detroit Metropolitan Wayne County

Mon 3/2

8:18 am-11:01 am

1 stop3h 43m

$429

Flights are sorted by cheapest round-trip flights first.

Deals found on 1/25

Compare providers for flights from Detroit to La Crosse

Provider information is updated monthly. Please note that these providers often have deals for this flight, but the availability may vary on a day-by-day basis on Cheapflights.
Use the table below to compare price accuracy, trust ratings, and cancellation policies for each provider offering flight deals from Detroit to La Crosse in January.
ProviderPrice AccuracyTrust Score*
ExpediaPrice Accuracy2 starsTrust Score*3 stars
FlightHubPrice Accuracy3 starsTrust Score*1 star

*The Trust Score is based on feedback from users after their booking experience. It measures overall satisfaction, helping us identify issues like hidden fees, problems during the ticketing process, and the quality of customer service. This score is our best indicator of the provider's quality and reliability.

  • Most accurate provider: When it comes to deals on Detroit Metropolitan Wayne County Airport-La Crosse flights, users find the pricing of FlightHub to be most consistent on Cheapflights vs. FlightHub Users can find the same prices on Detroit Metropolitan Wayne County Airport-La Crosse flight deals on Cheapflights vs. FlightHub >95% of the time. Price accuracy is based on data collected from Detroit Metropolitan Wayne County Airport-La Crosse flight searches over the past month and is updated monthly.
  • Most trusted provider: When it comes to deals on Detroit Metropolitan Wayne County Airport-La Crosse flights, Cheapflights users trust Expedia the most. Expedia has received a user feedback score of 3 out of 3 stars (3 being the best), meaning they have been trusted the most by Cheapflights users looking for Detroit Metropolitan Wayne County Airport-La Crosse flight deals. Provider user feedback score is based on Cheapflights searches over the past month and is updated monthly.

Best time to book a flight from Detroit to La Crosse

Have a flexible travel schedule? Discover the best time to fly to La Crosse from Detroit with our price prediction graph.
Estimated round-trip price
Rates are based on past data. Find the cheapest month and day to book your flight based on your travel requirements, then search for cheap deals.

Reviews of airlines servicing La Crosse

Get insights into the airlines that provide service to La Crosse. Read reviews, discover amenities, and learn about the overall travel experience offered by airlines. Use this information to make informed decisions when choosing an airline for your flight to La Crosse. Reviews last updated January 26, 2026.
Read reviews from past customers who have flown American Airlines from Detroit Metropolitan Wayne County Airport to La Crosse. Users can see the overall rating for each airline as well as how each is rated in terms of entertainment options, comfort, food, crew/service, and boarding process.
American Airlines
7.2
Good
11,189 reviews

Comfort

7.2

Food

6.4

Boarding

7.5

Crew

8.0

Entertainment

6.9

Overall

7.2

Reviews

1 / 20
2.0
Mediocre

Susie,Jan 2026

CLT - TPA

This flight was delayed 3 or 4 times. We had boarded the plane, sat on plane for a good 30 minutes, then we had to board the aircraft, walk to a different gate, wait and then board another aircraft. We arrived in Tampa 4 hours later than the original booking. I feel there should have been some sort of compensation especially for the advantage members.
American Airlines
7.2
Good
11,189 reviews
American Airlines
7.2
Good
11,189 reviews

Comfort

7.2

Food

6.4

Boarding

7.5

Crew

8.0

Entertainment

6.9

Overall

7.2

Reviews

1 / 20
2.0
Mediocre

Susie,Jan 2026

CLT - TPA

This flight was delayed 3 or 4 times. We had boarded the plane, sat on plane for a good 30 minutes, then we had to board the aircraft, walk to a different gate, wait and then board another aircraft. We arrived in Tampa 4 hours later than the original booking. I feel there should have been some sort of compensation especially for the advantage members.

Related info for your journey

Find useful and relevant information for your journey from Detroit to La Crosse. Access travel guides, tips, and recommendations to enhance your travel experience. Get information about local attractions, weather, transportation options, and more.

  • How long is the flight from Detroit Metropolitan Wayne County Airport to La Crosse?

    Departing from Detroit Metropolitan Wayne County Airport to La Crosse will take you 5h 57m. Airlines will cover a distance of 415 mi.

  • Can I find deals for flights from Detroit to La Crosse that include hotel bookings?

    Yes. In addition to deals on Detroit to La Crosse flights, Cheapflights offers vacation packages that include both flights and hotel.

  • How can I find direct flights from Detroit to La Crosse?

    After entering your origin and destination, apply the non-stop filter on the search result page to find direct flights from Detroit to La Crosse.

  • Can I find deals for business class flights from Detroit to La Crosse?

    Yes. Cheapflights offers flight deals from Detroit to La Crosse by cabin class. In addition to browsing deals, you can also filter by cabin class on the search results page after making a search.

See more FAQs

Traveling to a place near La Crosse?

Book flights to La Crosse if you plan to visit one of these locations
Decorah
Winona

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Top airline flying from Detroit to La Crosse

Discover the top airline that operate flights from Detroit to La Crosse. Compare their services, reliability, and customer satisfaction ratings to choose the airline that best suits your travel preferences and needs. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated January 26, 2026.
AirlineCheapestAverageFlexibilityOn-time
American AirlinesCheapest$414Average$468FlexibilityNo cancel feeOn-time71%

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