$299+ Cheap flights from Charleston to La Crosse (CHS - LSE)
This is the cheapest round-trip flight price found by a Cheapflights user in the last 72 hours by searching for a flight departing on 5/13. Fares are subject to change and may not be available on all flights or dates of travel.
CHS — LSE
May 23 — May 301
Round-trip
1 adult, Economy
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Cheapest
Best
Last-minute
Cheapest flights from Charleston to La CrosseExplore the most affordable flight options available from Charleston to La Crosse. Find the lowest fares from popular airlines and budget airlines, with prices last updated on April 23, 2026.
Explore the most affordable flight options available from Charleston to La Crosse. Find the lowest fares from popular airlines and budget airlines, with prices last updated on April 23, 2026.
This American Airlines deal was found by Cheapflights users on 4/19. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 5/1312:13 pm
CHS
- LSE
1 stop6h 53m
American Airlines
Tue 5/195:40 am
LSE
- CHS
1 stop5h 09m
American Airlines
Deal found 4/19![American Airlines logo]()
$299
This American Airlines deal was found by Cheapflights users on 4/19. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 5/196:32 pm
CHS
- LSE
1 stop6h 22m
American Airlines
Sat 5/2311:44 am
LSE
- CHS
2 stops11h 15m
American Airlines
Deal found 4/19![American Airlines logo]()
$329
Best flights from Charleston to La CrosseDiscover carefully curated flight deals from Charleston to La Crosse that have cost, travel time, and layovers in mind to ensure you get the best travel experience. Data last updated April 23, 2026.
Discover carefully curated flight deals from Charleston to La Crosse that have cost, travel time, and layovers in mind to ensure you get the best travel experience. Data last updated April 23, 2026.
This American Airlines deal was found by Cheapflights users on 4/19. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 5/1312:13 pm
CHS
- LSE
1 stop6h 53m
American Airlines
Tue 5/195:40 am
LSE
- CHS
1 stop5h 09m
American Airlines
Deal found 4/19![American Airlines logo]()
$299
This American Airlines deal was found by Cheapflights users on 4/19. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 5/196:32 pm
CHS
- LSE
1 stop6h 22m
American Airlines
Sat 5/2311:44 am
LSE
- CHS
2 stops11h 15m
American Airlines
Deal found 4/19![American Airlines logo]()
$329
This American Airlines deal was found by Cheapflights users on 4/18. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 5/812:29 pm
CHS
- LSE
1 stop6h 37m
American Airlines
Sat 5/165:40 am
LSE
- CHS
2 stops7h 19m
American Airlines
Deal found 4/18![American Airlines logo]()
$392
Last-minute flights from Charleston to La CrosseDiscover last-minute flight deals from Charleston to La Crosse. Data last updated April 23, 2026 and is based on user searches.
Discover last-minute flight deals from Charleston to La Crosse. Data last updated April 23, 2026 and is based on user searches.
This American Airlines deal was found by Cheapflights users on 4/19. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 5/1312:13 pm
CHS
- LSE
1 stop6h 53m
American Airlines
Tue 5/195:40 am
LSE
- CHS
1 stop5h 09m
American Airlines
Deal found 4/19![American Airlines logo]()
$299
This American Airlines deal was found by Cheapflights users on 4/19. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 5/196:32 pm
CHS
- LSE
1 stop6h 22m
American Airlines
Sat 5/2311:44 am
LSE
- CHS
2 stops11h 15m
American Airlines
Deal found 4/19![American Airlines logo]()
$329
Find flight deals from Charleston to La Crosse
Discover tips and strategies to find the most affordable flight options for your journey from Charleston (CHS) to La Crosse (LSE). Learn about various techniques such as flexible date searches, comparing prices across and setting up price alerts. Use these methods to find the cheapest flights available for your travel needs. Data last updated April 23, 2026.
Most accurate provider | FlightHub 3 stars |
|---|---|
Most trusted provider | FlightHub 3 stars |
Round-trip from | $299 (American Airlines) |
Cheapflights Fare Finder
Customize your flight search to find flights from Charleston to La Crosse that fit within your specific budget. Explore options based on user searches and filter the results based on your desired price range. Find flights that match your budget for a cost-effective journey. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated April 23, 2026.
Use the filters below to find and compare flights from Charleston to La Crosse that are best for you.
Fly from
Fly to
Route
Depart
Return
Cheapest round-trip
Quickest round-trip
CharlestonLa Crosse
CHS - LSE
CHSLSE
Charleston
Wed 5/13
12:13 pm-6:06 pm
1 stop6h 53m
La Crosse
Tue 5/19
5:40 am-11:49 am
1 stop5h 09m
$299
CharlestonLa Crosse
CHS - LSE
CHSLSE
Charleston
Tue 5/19
6:32 pm-11:54 pm
1 stop6h 22m
La Crosse
Sat 5/23
11:44 am-11:59 pm
2 stops11h 15m
$329
CharlestonLa Crosse
CHS - LSE
CHSLSE
Charleston
Fri 5/8
12:29 pm-6:06 pm
1 stop6h 37m
La Crosse
Sat 5/16
5:40 am-1:59 pm
2 stops7h 19m
$392
Sorted by cheapest first
- Most accurate provider: When it comes to deals on Charleston-La Crosse flights, users find the pricing of FlightHub to be most consistent on Cheapflights vs. FlightHub Users can find the same prices on Charleston-La Crosse flight deals on Cheapflights vs. FlightHub >95% of the time. Price accuracy is based on data collected from Charleston-La Crosse flight searches over the past month and is updated monthly.
- Most trusted provider: When it comes to deals on Charleston-La Crosse flights, Cheapflights users trust FlightHub the most. FlightHub has received a user feedback score of 3 out of 3 stars (3 being the best), meaning they have been trusted the most by Cheapflights users looking for Charleston-La Crosse flight deals. Provider user feedback score is based on Cheapflights searches over the past month and is updated monthly.
Best time to book a flight from Charleston to La Crosse
Have a flexible travel schedule? Discover the best time to fly to La Crosse from Charleston with our price prediction graph.
CHS-LSE
Estimated round-trip price
Rates are based on past data. Find the cheapest month and day to book your flight based on your travel requirements, then search for cheap deals.
Reviews of airlines servicing La Crosse
Get insights into the airlines that provide service to La Crosse. Read reviews, discover amenities, and learn about the overall travel experience offered by airlines. Use this information to make informed decisions when choosing an airline for your flight to La Crosse. Reviews last updated April 23, 2026.
Get a feel of what it's like to fly with American Airlines from Charleston to La Crosse by reading reviews from past customers. Users have also rated airlines in terms of entertainment options, comfort, food, crew/service, and boarding process.
Crew
7.9
Overall
7.1
Entertainment
6.9
Food
6.4
Boarding
7.5
Comfort
7.2
Reviews
1 / 20
4.0
OkayElizabeth,Mar 2026
ORD - MIA
Crew
7.9
Overall
7.1
Entertainment
6.9
Food
6.4
Boarding
7.5
Comfort
7.2
Reviews
1 / 20
4.0
OkayElizabeth,Mar 2026
ORD - MIA
Related info for your journey
Find useful and relevant information for your journey from Charleston to La Crosse. Access travel guides, tips, and recommendations to enhance your travel experience. Get information about local attractions, weather, transportation options, and more.
Traveling to a place near La Crosse?
Book flights to La Crosse if you plan to visit one of these locationsDecorah
Winona
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Other flights to La Crosse
Explore flights to La Crosse departing from other origins. Flights are based on user searches made on Cheapflights and were last updated on April 23, 2026.
Charleston and La Crosse flights
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Top airline flying from Charleston to La Crosse
Discover the top airline that operate flights from Charleston to La Crosse. Compare their services, reliability, and customer satisfaction ratings to choose the airline that best suits your travel preferences and needs. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated April 23, 2026.
| Airline | Cheapest | Average | Flexibility | On-time |
|---|---|---|---|---|
| Cheapest$461 | Average$586 | FlexibilityNo cancel fee | On-time71% |